Cardiac Output, High

A state of elevated cardiac output due to conditions of either increased hemodynamic demand or reduced cardiac oxygen output. These conditions may include ANEMIA; ARTERIOVENOUS FISTULA; THYROTOXICOSIS; PREGNANCY; EXERCISE; FEVER; and HYPOXIA. In time, compensatory changes of the heart can lead to pathological form of high cardiac output and eventual HEART FAILURE.

Synonyms(2)

Synonym
Cardiac Output, High
High Cardiac Output

Research Excerpts

Treatment

Excerpt	Reference
"Early treatment of high cardiac output with atenolol decreases the risk for preeclampsia."	( Brateng, DA; Carr, DB; Easterling, TR; Karumanchi, SA; Kawamura, C; Shofer, JB; Tran, LT, 2009)

Research

Studies (42)

Timeframe	Studies, This Condition (%)	All Conditions %
pre-1990	0 (0.00)	23.3326
1990's	13 (30.95)	12.5806
2000's	20 (47.62)	18.1394
2010's	9 (21.43)	28.8240
2020's	0 (0.00)	9.53

Drug	Relationship Strength	Studies	Trials
salicylic acid	low	1	0
lactic acid	low	1	0
nitrates	low	1	0
thiamine	low	3	0
atenolol	medium	2	1
furosemide	low	1	0
isoflurane	low	1	0
losartan	low	1	0
propofol	low	1	0
sevoflurane	low	1	0
prednisolone	low	1	0
aldosterone	low	1	0
phenylephrine	low	2	0
methylene blue	low	2	0
methacholine chloride	medium	1	1
arginine	medium	2	1
platinum	medium	1	1
calcium oxalate	low	1	0
ng-nitroarginine methyl ester	low	3	0
captopril	low	2	0
simvastatin	low	1	0
quinapril	low	1	0
simendan	low	1	0
fibrinogen	low	1	0
omega-n-methylarginine	medium	2	1
angiotensin ii	low	2	0
lithium chloride	low	3	0
digoxin	low	1	0
alprostadil	low	1	0
pituitrin	low	2	0
atrial natriuretic factor	low	2	0
endothelin-1	medium	1	1
natriuretic peptide, brain	low	1	0
technetium tc 99m sulfur colloid	low	1	0
adrenomedullin	low	1	0
cyclic gmp	low	1	0

Protein Targets (474)

Protein	Potency Measurements	Inhibition Measurements	Activation Measurements	Drugs
AR protein	11	0	0	11
glucocorticoid receptor [Homo sapiens]	7	0	0	7
thyroid hormone receptor beta isoform a	3	0	0	3
nuclear factor erythroid 2-related factor 2 isoform 2	6	0	0	6
geminin	7	0	0	7
Sex hormone-binding globulin	0	0	1	1
Corticosteroid-binding globulin	0	2	0	2
Mineralocorticoid receptor	0	3	3	6
Androgen receptor	0	2	0	2
Mineralocorticoid receptor	0	1	0	1
Solute carrier organic anion transporter family member 1A1	0	0	0	1
Guanine nucleotide-binding protein G	2	0	0	2
TDP1 protein	7	0	0	7
estrogen nuclear receptor alpha	11	0	0	11
peroxisome proliferator activated receptor gamma	5	0	0	5
ATP-binding cassette sub-family C member 3	0	7	0	7
Multidrug resistance-associated protein 4	0	7	0	9
Bile salt export pump	0	10	0	10
Cellular tumor antigen p53	7	0	0	7
Thromboxane-A synthase	0	1	0	1
Prostaglandin E2 receptor EP3 subtype	0	1	0	1
Prostaglandin E2 receptor EP4 subtype	0	1	1	2
Prostaglandin E2 receptor EP1 subtype	0	1	0	1
Prostacyclin receptor	0	1	1	2
Nuclear receptor subfamily 4 group A member 2	0	0	2	2
Solute carrier organic anion transporter family member 2A1	0	1	0	2
Nuclear receptor subfamily 4 group A member 2	0	0	1	1
Nuclear receptor subfamily 4 group A member 2	0	0	1	1
Prostaglandin E2 receptor EP2 subtype	0	1	1	2
Canalicular multispecific organic anion transporter 1	0	6	0	6
Solute carrier organic anion transporter family member 2A1	0	0	0	1
Solute carrier organic anion transporter family member 2B1	0	1	0	1
Solute carrier organic anion transporter family member 3A1	0	0	0	1
glucocerebrosidase	1	0	0	1
DNA polymerase kappa isoform 1	1	0	0	1
histone acetyltransferase KAT2A isoform 1	3	0	0	3
Atrial natriuretic peptide receptor 3	0	2	0	2
Type-1A angiotensin II receptor	0	4	2	6
Type-1 angiotensin II receptor	0	0	1	1
Type-1B angiotensin II receptor	0	4	0	4
Type-1 angiotensin II receptor	0	4	3	9
Type-2 angiotensin II receptor	0	4	0	4
Type-2 angiotensin II receptor	0	3	0	3
Chain A, MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASE	6	0	0	6
Chain E, LYSINE, ARGININE, ORNITHINE-BINDING PROTEIN	0	0	1	1
Chain E, LYSINE, ARGININE, ORNITHINE-BINDING PROTEIN	0	0	1	1
Chain E, LYSINE, ARGININE, ORNITHINE-BINDING PROTEIN	0	0	1	1
thioredoxin reductase	5	0	0	5
phosphopantetheinyl transferase	3	0	0	3
NFKB1 protein, partial	2	0	0	2
GLS protein	3	0	0	3
thyroid stimulating hormone receptor	4	0	0	4
alpha-galactosidase	2	0	0	2
euchromatic histone-lysine N-methyltransferase 2	8	0	0	8
cytochrome P450 2C19 precursor	2	0	0	2
chromobox protein homolog 1	2	0	0	2
flap endonuclease 1	4	0	0	4
DNA polymerase iota isoform a (long)	5	0	0	5
muscarinic acetylcholine receptor M1	3	0	0	3
lethal factor (plasmid)	3	0	0	3
Cytochrome P450 3A4	0	1	0	2
Nitric oxide synthase, endothelial	0	2	0	4
Nitric oxide synthase, brain	0	3	0	4
Nitric oxide synthase, brain	0	2	0	3
Nitric oxide synthase, inducible	0	2	0	3
Nitric oxide synthase, inducible	0	3	1	6
Cationic amino acid transporter 3	0	1	0	1
ATP-dependent phosphofructokinase	6	0	0	6
Chain A, TYROSYL-DNA PHOSPHODIESTERASE	2	0	0	2
regulator of G-protein signaling 4	3	0	0	3
Beta-1 adrenergic receptor	0	0	1	1
D(1A) dopamine receptor	4	0	0	4
lamin isoform A-delta10	4	0	0	4
Gamma-aminobutyric acid receptor subunit pi	3	1	2	6
Fatty acid-binding protein, liver	0	2	0	2
Urease	0	1	0	1
Beta-2 adrenergic receptor	0	2	2	4
Beta-1 adrenergic receptor	0	2	2	4
Beta-3 adrenergic receptor	0	0	2	2
Gamma-aminobutyric acid receptor subunit beta-1	3	1	2	6
Gamma-aminobutyric acid receptor subunit delta	3	1	2	6
Gamma-aminobutyric acid receptor subunit gamma-2	3	1	2	6
5-hydroxytryptamine receptor 1A	0	2	1	3
Gamma-aminobutyric acid receptor subunit alpha-5	3	1	2	6
Gamma-aminobutyric acid receptor subunit alpha-3	3	1	2	6
Gamma-aminobutyric acid receptor subunit gamma-1	3	1	2	6
Gamma-aminobutyric acid receptor subunit alpha-2	3	1	2	6
Alpha-1D adrenergic receptor	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-4	3	1	2	6
Gamma-aminobutyric acid receptor subunit gamma-3	3	1	2	6
Gamma-aminobutyric acid receptor subunit alpha-6	3	1	2	6
Alpha-1A adrenergic receptor	0	2	1	3
Alpha-1B adrenergic receptor	0	2	1	3
Gamma-aminobutyric acid receptor subunit alpha-1	3	1	2	6
Gamma-aminobutyric acid receptor subunit beta-3	3	1	2	6
Gamma-aminobutyric acid receptor subunit beta-2	3	1	2	6
TAR DNA-binding protein 43	4	0	0	4
Beta-2 adrenergic receptor	0	0	1	1
GABA theta subunit	3	1	2	6
Gamma-aminobutyric acid receptor subunit epsilon	3	1	2	6
Atrial natriuretic peptide receptor 1	0	1	1	2
Atrial natriuretic peptide receptor 1	0	0	1	1
GLI family zinc finger 3	8	0	0	8
progesterone receptor	5	0	0	5
retinoic acid nuclear receptor alpha variant 1	9	0	0	9
estrogen-related nuclear receptor alpha	7	0	0	7
Histone H2A.x	4	0	0	4
Voltage-dependent calcium channel gamma-2 subunit	4	0	0	4
Glutamate receptor 2	4	0	0	4
Chain A, angiotensin converting enzyme	0	1	0	1
Chain A, angiotensin converting enzyme	0	1	0	1
Chain A, HADH2 protein	1	0	0	1
Chain B, HADH2 protein	1	0	0	1
Chain A, 2-oxoglutarate Oxygenase	3	0	0	3
15-lipoxygenase, partial	1	0	0	1
Microtubule-associated protein tau	3	0	0	3
Thrombopoietin	1	0	0	1
thioredoxin glutathione reductase	3	0	0	3
cytochrome P450 family 3 subfamily A polypeptide 4	11	0	0	11
Metallo-beta-lactamase type 2	0	1	1	2
peripheral myelin protein 22 isoform 1	1	0	0	1
M-phase phosphoprotein 8	1	0	0	1
transient receptor potential cation channel subfamily V member 1	1	0	0	1
Prothrombin	0	1	0	1
Renin	0	1	0	1
Neprilysin	0	1	0	1
Neprilysin	0	2	0	2
Leukotriene A-4 hydrolase	0	2	1	3
EEF1AKMT4-ECE2 readthrough transcript protein	0	1	0	1
Angiotensin-converting enzyme	0	4	1	5
Angiotensin-converting enzyme	0	3	0	4
Leukotriene A-4 hydrolase	0	1	0	1
Thymidine phosphorylase	0	0	1	1
Prostaglandin G/H synthase 1	0	3	0	3
Prostaglandin G/H synthase 2	0	4	0	4
Endothelin-converting enzyme 1	0	1	0	1
Succinyl-diaminopimelate desuccinylase	0	2	0	2
Angiotensin-converting enzyme	0	2	0	2
Solute carrier family 15 member 1	0	1	0	1
Beta-lactamase TEM	0	1	0	1
Mu-type opioid receptor	0	0	1	1
Beta-lactamase	0	2	0	3
Beta-lactamase	0	2	0	2
Angiotensin-converting enzyme 2	0	2	0	2
Beta-lactamase class B VIM-2	0	1	1	2
Phosphodiesterase	0	1	0	1
Multidrug resistance-associated protein 5	0	0	0	1
cGMP-inhibited 3',5'-cyclic phosphodiesterase B	0	2	0	2
cGMP-inhibited 3',5'-cyclic phosphodiesterase A	0	2	0	2
Chain A, Beta-lactamase	2	0	0	2
Chain A, ATP-DEPENDENT DNA HELICASE Q1	2	0	0	2
Chain A, Cruzipain	2	0	0	2
interleukin 8	1	0	0	1
PAX8	0	0	0	1
RAR-related orphan receptor gamma	8	0	0	8
SMAD family member 2	3	0	0	3
ATAD5 protein, partial	2	0	0	2
PPM1D protein	2	0	0	2
SMAD family member 3	3	0	0	3
STAT3, partial	0	1	0	1
Smad3	3	0	0	3
estrogen receptor 2 (ER beta)	5	0	0	5
nuclear receptor subfamily 1, group I, member 3	3	0	0	3
retinoid X nuclear receptor alpha	4	0	0	4
farnesoid X nuclear receptor	5	0	0	5
pregnane X nuclear receptor	4	0	0	4
67.9K protein	1	0	0	1
peroxisome proliferator-activated receptor delta	3	0	0	3
vitamin D (1,25- dihydroxyvitamin D3) receptor	2	0	0	2
IDH1	3	0	0	3
cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a	5	0	0	5
thyroid stimulating hormone receptor	4	0	0	4
activating transcription factor 6	3	0	0	3
nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105), isoform CRA_a	4	0	0	4
v-jun sarcoma virus 17 oncogene homolog (avian)	7	0	0	7
NPC intracellular cholesterol transporter 1 precursor	1	0	0	1
cellular tumor antigen p53 isoform a	2	0	0	2
tumor necrosis factor	1	0	0	1
parathyroid hormone/parathyroid hormone-related peptide receptor precursor	2	0	0	2
thyroid hormone receptor beta isoform 2	5	0	0	5
ras-related protein Rab-9A	2	0	0	2
nuclear factor erythroid 2-related factor 2 isoform 1	4	0	0	4
signal transducer and activator of transcription 1-alpha/beta isoform alpha	0	1	0	1
nuclear receptor ROR-gamma isoform 1	1	0	0	1
Solute carrier organic anion transporter family member 1A4	0	1	0	2
Interferon beta	6	0	0	6
Sodium/potassium-transporting ATPase subunit alpha-1	0	2	0	2
Sodium/potassium-transporting ATPase subunit beta-1	0	2	0	2
Integrin beta-3	2	0	0	2
Sodium/potassium-transporting ATPase subunit alpha-2	0	1	0	1
Sodium/potassium-transporting ATPase subunit alpha-3	0	1	0	1
ATP-dependent translocase ABCB1	0	1	0	1
Sodium/potassium-transporting ATPase subunit beta-1	0	1	0	1
ATP-dependent translocase ABCB1	0	2	0	4
Integrin alpha-IIb	2	0	0	2
Replicase polyprotein 1ab	0	1	0	1
Sodium/potassium-transporting ATPase subunit alpha-3	0	1	0	1
Sodium/potassium-transporting ATPase subunit beta-2	0	1	0	1
ATP-dependent translocase ABCB1	0	1	0	1
Sodium/potassium-transporting ATPase subunit alpha-2	0	2	0	2
Sodium/potassium-transporting ATPase subunit alpha-1	0	1	0	1
Nuclear receptor ROR-gamma	1	1	1	3
Sodium/potassium-transporting ATPase subunit beta-3	0	1	0	1
Sodium/potassium-transporting ATPase subunit gamma	0	1	0	1
Sodium/potassium-transporting ATPase subunit alpha-4	0	1	0	1
Sodium/potassium-transporting ATPase subunit alpha-4	0	1	0	1
Solute carrier organic anion transporter family member 4C1	0	0	0	1
Solute carrier organic anion transporter family member 4C1	0	0	0	1
ATPase family AAA domain-containing protein 5	4	0	0	4
Ataxin-2	4	0	0	4
Solute carrier organic anion transporter family member 1A4	0	0	0	1
Solute carrier organic anion transporter family member 1B3	0	3	0	3
Solute carrier organic anion transporter family member 1B1	0	4	0	4
Endothelin-1 receptor	0	1	0	1
aldehyde dehydrogenase 1 family, member A1	3	0	0	3
EWS/FLI fusion protein	4	0	0	4
aryl hydrocarbon receptor	3	0	0	3
thyrotropin-releasing hormone receptor	2	0	0	2
Solute carrier family 22 member 6	0	2	0	2
Carbonic anhydrase 12	0	2	0	3
Bile salt export pump	0	2	0	2
Carbonic anhydrase 1	0	6	0	7
Carbonic anhydrase 2	0	6	0	7
Albumin	0	2	0	2
Carbonic anhydrase 3	0	2	0	2
Glucose-6-phosphate 1-dehydrogenase	0	1	0	1
Cytochrome P450 2C9	0	3	0	3
Carbonic anhydrase 4	0	3	0	4
Carbonic anhydrase 6	0	3	0	4
Serum paraoxonase/arylesterase 1	0	1	0	1
Corticosteroid 11-beta-dehydrogenase isozyme 1	0	1	0	1
Carbonic anhydrase 5A, mitochondrial	0	2	0	3
Carbonic anhydrase 7	0	2	0	3
Adenosine receptor A1	0	1	0	1
Corticosteroid 11-beta-dehydrogenase isozyme 1	0	1	0	1
Cytochrome P450 2J2	0	2	0	2
6-phosphogluconate dehydrogenase, decarboxylating	0	1	0	1
Spike glycoprotein	5	0	0	5
Holo-[acyl-carrier-protein] synthase	0	1	0	1
Sodium/bile acid cotransporter	0	1	0	1
Carbonic anhydrase 9	0	2	0	3
Multidrug and toxin extrusion protein 1	0	2	0	2
Carbonic anhydrase 13	0	2	0	3
G-protein coupled receptor 35	0	1	1	2
CDGSH iron-sulfur domain-containing protein 1	0	2	0	2
Carbonic anhydrase 14	0	2	0	3
Broad substrate specificity ATP-binding cassette transporter ABCG2	0	2	0	2
Carbonic anhydrase 5B, mitochondrial	0	2	0	3
Neuronal acetylcholine receptor subunit beta-2	0	1	0	1
Neuronal acetylcholine receptor subunit alpha-7	0	1	0	1
acetylcholinesterase	2	0	0	2
cytochrome P450 2D6	4	0	0	4
arylsulfatase A	2	0	0	2
potassium voltage-gated channel subfamily H member 2 isoform d	1	0	0	1
cytochrome P450 3A4 isoform 1	3	0	0	3
inositol monophosphatase 1	1	0	0	1
Cholecystokinin receptor type A	1	0	0	1
Gastrin/cholecystokinin type B receptor	1	0	0	1
Glycogen synthase kinase-3 beta	0	1	1	2
G	4	0	0	4
HLA class I histocompatibility antigen, B alpha chain	4	0	0	4
Thromboxane A2 receptor	0	1	0	2
cAMP-specific 3',5'-cyclic phosphodiesterase 4A	0	1	0	1
Adenosine receptor A2a	0	1	0	1
Type-1 angiotensin II receptor	0	1	1	2
Squalene synthase	0	1	0	1
cAMP-specific 3',5'-cyclic phosphodiesterase 4B	0	1	0	1
cAMP-specific 3',5'-cyclic phosphodiesterase 4C	0	1	0	1
cAMP-specific 3',5'-cyclic phosphodiesterase 4D	0	1	0	1
Inositol hexakisphosphate kinase 1	4	0	0	4
Platelet glycoprotein VI	0	1	1	3
Type-1 angiotensin II receptor	0	1	1	2
cytochrome P450 2C9, partial	4	0	0	4
glp-1 receptor, partial	3	0	0	3
GALC protein	1	0	0	1
Bloom syndrome protein isoform 1	3	0	0	3
galanin receptor type 3	0	1	0	1
survival motor neuron protein isoform d	3	0	0	3
Chain E, Fibrin beta chain	0	1	0	1
Chain A, Putative fructose-1,6-bisphosphate aldolase	1	0	0	1
Chain A, JmjC domain-containing histone demethylation protein 3A	2	0	0	2
Chain A, Ferritin light chain	3	0	0	3
Luciferase	2	0	0	2
T cell receptor, partial	1	0	0	1
luteinizing hormone receptor	1	0	0	1
integrase, partial	0	1	0	1
chaperonin-containing TCP-1 beta subunit homolog	2	0	0	2
lens epithelium-derived growth factor p75	0	1	0	1
hypoxia-inducible factor 1 alpha subunit	3	0	0	3
Caspase 6, apoptosis-related cysteine peptidase	0	0	0	1
Fumarate hydratase	1	0	0	1
TSHR protein	1	0	0	1
Apoptotic peptidase activating factor 1	0	1	0	1
caspase 7, apoptosis-related cysteine protease	2	0	0	2
hypothetical protein, conserved	1	0	0	1
isocitrate dehydrogenase 1, partial	1	0	0	1
polyprotein	1	0	0	1
luciferase	1	0	0	1
bromodomain adjacent to zinc finger domain 2B	2	0	0	2
caspase-3	2	0	0	2
serine-protein kinase ATM isoform a	1	0	0	1
neutrophil cytosol factor 1	0	1	0	1
caspase-9 isoform alpha precursor	0	1	0	1
histone deacetylase 9 isoform 3	1	0	0	1
heat shock protein beta-1	3	0	0	3
huntingtin isoform 2	1	0	0	1
pyruvate kinase PKM isoform a	1	0	0	1
DNA polymerase beta	1	0	0	1
mitogen-activated protein kinase 1	1	0	0	1
caspase-3 isoform a preproprotein	0	1	0	1
protein AF-9 isoform a	0	0	0	1
histone-lysine N-methyltransferase 2A isoform 2 precursor	1	0	0	1
peptidyl-prolyl cis-trans isomerase NIMA-interacting 1	1	0	0	1
DNA polymerase eta isoform 1	1	0	0	1
urokinase-type plasminogen activator precursor	2	0	0	2
plasminogen precursor	2	0	0	2
urokinase plasminogen activator surface receptor precursor	2	0	0	2
Vpr	1	0	0	1
muscleblind-like protein 1 isoform 1	1	0	0	1
replicative DNA helicase	0	0	0	1
recombinase A	0	0	1	1
POsterior Segregation	0	0	1	1
DNA repair protein RAD52 homolog isoform a	0	0	0	1
neuropeptide S receptor isoform A	1	0	0	1
Glutathione reductase	0	1	0	1
Glutathione reductase, mitochondrial	0	1	0	2
Glycoprotein hormones alpha chain	1	0	0	1
Albumin	0	0	0	1
Amyloid-beta precursor protein	0	1	0	1
Dihydrolipoyl dehydrogenase, mitochondrial	0	1	0	2
Microtubule-associated protein tau	0	1	1	2
Alpha-1B adrenergic receptor	0	2	0	2
Amine oxidase [flavin-containing] A	0	1	0	1
Alpha-1D adrenergic receptor	0	2	0	2
Sodium-dependent noradrenaline transporter	0	2	1	3
Cruzipain	0	1	0	1
Alpha-synuclein	1	0	0	1
Alpha-1A adrenergic receptor	0	2	0	2
Inositol monophosphatase 1	1	0	0	1
Thioredoxin reductase 1, cytoplasmic	0	1	0	2
Dihydrolipoyl dehydrogenase	0	1	0	2
Zinc finger protein mex-5	0	0	1	1
phosphoglycerate kinase	1	0	0	1
Neutrophil elastase	0	2	0	2
Nitric oxide synthase, endothelial	0	3	0	3
Collagenase 3	0	2	0	2
Carbonic anhydrase	0	1	0	1
Sodium/iodide cotransporter	0	1	0	1
Carbonic anhydrase 15	0	2	0	2
vitamin D3 receptor isoform VDRA	2	0	0	2
N(G),N(G)-dimethylarginine dimethylaminohydrolase 1	0	0	0	1
N(G),N(G)-dimethylarginine dimethylaminohydrolase 1	0	1	0	2
Proteinase-activated receptor 1	0	1	0	1
Nitric oxide synthase, brain	0	1	0	1
dopamine D1 receptor	1	0	0	1
hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)	2	0	0	2
Alpha-1B adrenergic receptor	0	0	1	1
Alpha-2A adrenergic receptor	0	1	1	2
POU domain, class 2, transcription factor 1	0	0	0	1
Alpha-2B adrenergic receptor	0	1	0	1
Beta-1 adrenergic receptor	0	1	0	1
Alpha-1A adrenergic receptor	0	1	1	2
Alpha-2C adrenergic receptor	0	1	1	2
Alpha-1B adrenergic receptor	0	1	0	1
Alpha-2B adrenergic receptor	0	1	0	1
Alpha-2C adrenergic receptor	0	1	0	1
Alpha-2A adrenergic receptor	0	1	0	1
Alpha-2B adrenergic receptor	0	0	0	1
Alpha-2C adrenergic receptor	0	0	0	1
Alpha-2A adrenergic receptor	0	0	0	1
luciferase	0	0	0	1
nuclear receptor subfamily 1, group I, member 2	2	0	0	2
Estrogen receptor	0	2	0	2
Glucocorticoid receptor	0	2	1	8
Progesterone receptor	0	2	0	3
Glucocorticoid receptor	0	1	1	2
Glucocorticoid receptor	0	0	1	1
Glycine receptor subunit alpha-1	0	2	0	2
Androgen receptor	0	2	0	2
Glutamine synthetase	0	0	1	1
Glycine receptor subunit beta	0	2	0	2
Glycine receptor subunit alpha-2	0	2	0	2
Glycine receptor subunit alpha-3	0	2	0	2
Histamine H1 receptor	0	0	1	1
Nociceptin receptor	0	0	1	1
Estrogen receptor beta	0	2	0	2
Chain A, Ferritin light chain	0	0	1	1
Chain A, Ferritin light chain	0	0	1	1
Chain A, Ferritin light chain	0	0	1	1
Chain A, Ferritin light chain	0	0	1	1
Chain A, Ferritin light chain	0	0	1	1
Chain A, Ferritin light chain	0	0	1	1
Chain A, Ferritin light chain	0	0	1	1
USP1 protein, partial	1	0	0	1
15-hydroxyprostaglandin dehydrogenase [NAD(+)] isoform 1	2	0	0	2
Fatty-acid amide hydrolase 1	0	1	0	1
UDP-glucuronosyltransferase 1A9	0	0	0	1
5-hydroxytryptamine receptor 4	0	2	0	2
Aldo-keto reductase family 1 member B1	0	2	0	2
Gamma-aminobutyric acid receptor subunit alpha-1	0	0	0	1
Gamma-aminobutyric acid receptor subunit beta-1	0	0	0	1
Gamma-aminobutyric acid receptor subunit alpha-2	0	0	0	1
Gamma-aminobutyric acid receptor subunit alpha-3	0	0	0	1
Polyunsaturated fatty acid lipoxygenase ALOX15	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-1	0	1	1	2
Gamma-aminobutyric acid receptor subunit beta-1	0	0	1	1
Gamma-aminobutyric acid receptor subunit gamma-2	0	1	1	2
Gamma-aminobutyric acid receptor subunit alpha-4	0	0	0	1
Gamma-aminobutyric acid receptor subunit gamma-2	0	0	0	1
Sodium- and chloride-dependent GABA transporter 1	0	1	0	1
5-hydroxytryptamine receptor 2C	0	2	0	2
Gamma-aminobutyric acid receptor subunit beta-3	0	1	1	2
Gamma-aminobutyric acid receptor subunit alpha-5	0	0	1	1
Sodium- and chloride-dependent GABA transporter 2	0	1	0	1
Sodium- and chloride-dependent GABA transporter 3	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-3	0	0	1	1
5-hydroxytryptamine receptor 2B	0	2	0	2
Gamma-aminobutyric acid receptor subunit alpha-2	0	0	1	1
Gamma-aminobutyric acid receptor subunit beta-2	0	0	1	1
Sodium- and chloride-dependent betaine transporter	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-4	0	0	1	1
Fatty-acid amide hydrolase 1	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-6	0	0	1	1
UDP-glucuronosyltransferase 1A8	0	0	0	1
Liver carboxylesterase 1	0	0	0	1
Estrogen receptor beta	0	0	0	1
Inhibitor of nuclear factor kappa-B kinase subunit beta	0	0	0	1
Polyphenol oxidase 2	0	1	0	2
5'-AMP-activated protein kinase subunit beta-2	0	0	0	1
Polymerase acidic protein	0	0	1	1
Stromelysin-1	0	0	1	1
Tyrosine-protein phosphatase YopH	0	1	0	1
High mobility group protein B1	0	0	1	1
Aldo-keto reductase family 1 member B1	0	1	0	1
Prolyl 4-hydroxylase subunit alpha-1	0	1	0	1
Tyrosine-protein phosphatase non-receptor type 1	0	1	0	3
Estrogen receptor	0	0	0	1
Acetylcholinesterase	0	1	0	1
Cystathionine gamma-lyase	0	1	0	1
5'-AMP-activated protein kinase subunit gamma-1	0	0	0	1
5'-AMP-activated protein kinase catalytic subunit alpha-2	0	0	0	1
Xanthine dehydrogenase/oxidase	0	1	0	1
5'-AMP-activated protein kinase catalytic subunit alpha-1	0	0	0	1
Carbonic anhydrase	0	1	0	1
Solute carrier family 22 member 6	0	1	0	1
Solute carrier family 22 member 7	0	0	0	1
Nicotinate phosphoribosyltransferase	0	1	0	1
Solute carrier family 22 member 20	0	1	0	1
Solute carrier family 22 member 8	0	1	0	1
Solute carrier family 22 member 6	0	1	0	1
Ubiquitin-like domain-containing CTD phosphatase 1	0	1	0	1
5'-AMP-activated protein kinase subunit gamma-3	0	0	0	1
5'-AMP-activated protein kinase subunit gamma-2	0	0	0	1
5'-AMP-activated protein kinase subunit beta-1	0	0	0	1
PINK1	1	0	0	1
Parkin	1	0	0	1
photoreceptor-specific nuclear receptor	0	1	0	1
serine/threonine-protein kinase PLK1	1	0	0	1
transactivating tegument protein VP16 [Human herpesvirus 1]	0	1	0	1
DNA dC->dU-editing enzyme APOBEC-3G isoform 1	1	0	0	1
3-hydroxy-3-methylglutaryl-coenzyme A reductase	0	2	0	2
Insulin receptor	0	1	0	1
3-hydroxy-3-methylglutaryl-coenzyme A reductase	0	1	0	1
3-hydroxy-3-methylglutaryl-coenzyme A reductase	0	1	0	1
Sigma non-opioid intracellular receptor 1	0	1	0	1
Chain A, ykoF	0	0	1	1
Chain B, ykoF	0	0	1	1
Chain A, ThiT	0	0	1	1
Thiamine transporter ThiT	0	0	1	1
Solute carrier family 22 member 1	0	1	0	2
Transketolase	0	0	1	1
Thiamine-binding periplasmic protein	0	0	1	1
Solute carrier family 22 member 1	0	1	0	1
Solute carrier family 22 member 2	0	1	0	1
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]

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