Conditions > Bullous Type of Ichthyosis
Page last updated: 2024-09-27

Bullous Type of Ichthyosis

An autosomal dominant form of ichthyosis characterized by generalized reddening of the skin (ERYTHEMA) and widespread blistering. The disease shows similar, but somewhat milder, clinical and histopathological findings to those in HYPERKERATOSIS, EPIDERMOLYTIC and is associated with the gene that encodes KERATIN-2A.

Synonyms(4)

Synonym
Ichthyosis Bullosa of Siemens
Bullous Type of Ichthyosis
Ichthyosis, Bullous Type
Ichthyosis, Bullous Type of Siemens

Research

Studies (2)

TimeframeStudies, This Condition (%)All Conditions %
pre-19900 (0.00)23.3326
1990's0 (0.00)12.5806
2000's0 (0.00)18.1394
2010's1 (50.00)28.8240
2020's1 (50.00)9.53
DrugIndicatedRelationship StrengthStudiesTrials
bromochloroacetic acid0low20

Protein Targets (9)

ProteinPotency MeasurementsInhibition MeasurementsActivation MeasurementsDrugs
RAR-related orphan receptor gamma1001
AR protein1001
aldehyde dehydrogenase 1 family, member A11001
nuclear receptor subfamily 1, group I, member 31001
retinoic acid nuclear receptor alpha variant 11001
thyroid stimulating hormone receptor1001
nuclear factor erythroid 2-related factor 2 isoform 11001
Cellular tumor antigen p531001
Nuclear receptor ROR-gamma1001
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]