Page last updated: 2024-09-27

Brain Injuries, Penetrating

Head injuries which feature compromise of the skull and dura mater. These may result from gunshot wounds (WOUNDS, GUNSHOT), stab wounds (WOUNDS, STAB), and other forms of trauma.

Synonyms(9)

Synonym
Head Trauma, Penetrating
Craniocerebral Trauma, Penetrating
Missile Injuries, Penetrating, Head
Head Injuries, Penetrating, Missile
Brain Injuries, Penetrating
Penetrating Missile Injuries, Head
Head Injuries, Penetrating
Cranial Trauma, Penetrating
Head Injury, Penetrating

Research Excerpts

Overview

ExcerptReference
"Although penetrating head injuries are very rare in Japan, an extremely rare case is reported in which an ivory chip, embedded in the subcutaneous tissue by a cosmetic rhinoplasty, penetrated the cranium."( Aishima, K; Hara, T; Inoue, M; Matsubayashi, S; Miyahara, M; Ohno, H; Okamoto, K; Tamai, Y, 2016)
"Transnasal penetrating brain injuries are rare and a medical emergency, which needs to be treated promptly."( Alataş, N; Güllüev, M; Yücel, A; Yücel, H, 2018)

Treatment

ExcerptReference
"We present here a case of penetrating head injury caused by stabbing a scissor in head by a local witch doctor in order to treat a psychiatric ailment."( Kumar, A; Pandey, R; Sharma, V; Singh, K, 2011)
"Transnasal penetrating brain injuries are rare and a medical emergency, which needs to be treated promptly."( Alataş, N; Güllüev, M; Yücel, A; Yücel, H, 2018)
"Although the immediate treatment of penetrating head injury is needed, surgical strategies are varied based on the trajectory of the penetrating objects in the cranium."( Fujii, Y; Hanaoka, Y; Horiuchi, T; Kurokawa, T; Ogihara, N; Yako, T; Yamazaki, D, 2023)

Research

Studies (179)

TimeframeStudies, This Condition (%)All Conditions %
pre-19900 (0.00)23.3326
1990's2 (1.12)12.5806
2000's68 (37.99)18.1394
2010's95 (53.07)28.8240
2020's14 (7.82)9.53
DrugIndicatedRelationship StrengthStudiesTrials
gamma-aminobutyric acid0low20
hydrochloric acid0low10
salicylic acid0low90
lactic acid0low10
glycerol0low20
methanol0low110
oxalic acid0low10
pyruvic acid0low10
toluene0low10
phenytoin0low20
aspirin0low10
brotizolam0low10
caffeine0low20
chloroquine0low10
citalopram0low10
dimercaprol0low10
doxylamine0low10
ethosuximide0low10
gabapentin0low20
isoflurane0low10
metronidazole0low10
apnea0low10
nortriptyline0low10
phenobarbital0low10
piracetam0low20
succinylcholine0low10
tranexamic acid0low20
edetic acid0low10
isoprene0low40
peracetic acid0low10
ethylbenzene0low10
thiophenes0low10
trinitrotoluene0low10
congo red0low10
acetylcysteine0low10
titanium0low10
barium sulfate0low10
tetradecanoylphorbol acetate0low10
4-methoxyamphetamine0low30
glutamic acid0low10
cefazolin0low10
propiconazole0low530
colforsin0low20
fenoxycarb0low10
simvastatin0low10
fadrozole0low10
trazodone hydrochloride0low10
fibrinogen0low10
glucuronic acid0low10
glycogen0low10
fibrin0low20
clindamycin0low10
tamoxifen0low20
phenylephrine hydrochloride0low90
levetiracetam0low20
morphine0low10
deamino arginine vasopressin0low20
lead0low20
antimony0low20
barium0low20
aluminum0low10
dextromethorphan0low20
cefotaxime0low10
mocetinostat0low10
n-acetylcysteinamide0low10
nnz 25660low20
technetium tc 99m exametazime0low10
indocyanine green0low10
mefloquine0low20
protectin d10low10
cytochrome c-t0low10
ro13-99040low10
heme0low10
minocycline0low10
calca protein, human0low10
transforming growth factor beta0low10
agar0low20
xjb-5-1310low10
exudates0low10
clozapine0low10

Protein Targets (886)

ProteinPotency MeasurementsInhibition MeasurementsActivation MeasurementsDrugs
5-hydroxytryptamine receptor 2C0415
5-hydroxytryptamine receptor 2A0416
5-hydroxytryptamine receptor 1A010111
5-hydroxytryptamine receptor 1B0718
5-hydroxytryptamine receptor 1D0415
5-hydroxytryptamine receptor 1F0415
5-hydroxytryptamine receptor 2B0426
5-hydroxytryptamine receptor 60112
Sodium-dependent serotonin transporter010212
Sodium-dependent serotonin transporter0404
5-hydroxytryptamine receptor 7 0213
5-hydroxytryptamine receptor 5A0112
5-hydroxytryptamine receptor 5B0112
5-hydroxytryptamine receptor 3A0213
5-hydroxytryptamine receptor 4 0112
5-hydroxytryptamine receptor 3B0213
Chain A, JmjC domain-containing histone demethylation protein 3A5005
Chain A, 2-oxoglutarate Oxygenase6006
Chain A, ATP-DEPENDENT DNA HELICASE Q11001
acetylcholinesterase6006
dopamine D1 receptor2002
15-lipoxygenase, partial1001
pregnane X receptor4004
phosphopantetheinyl transferase6006
RAR-related orphan receptor gamma170017
USP1 protein, partial4004
NFKB1 protein, partial2002
Microtubule-associated protein tau6006
Thrombopoietin2002
AR protein250025
regulator of G-protein signaling 47007
glucocorticoid receptor [Homo sapiens]190019
retinoic acid nuclear receptor alpha variant 1190019
retinoid X nuclear receptor alpha110011
farnesoid X nuclear receptor7007
estrogen nuclear receptor alpha270027
vitamin D (1,25- dihydroxyvitamin D3) receptor9009
arylsulfatase A9009
euchromatic histone-lysine N-methyltransferase 2210021
Bloom syndrome protein isoform 19009
D(1A) dopamine receptor8008
thyroid hormone receptor beta isoform a9009
thyroid hormone receptor beta isoform 2160016
heat shock protein beta-13003
flap endonuclease 16006
geminin140014
peripheral myelin protein 228008
survival motor neuron protein isoform d5005
muscarinic acetylcholine receptor M18008
Histone deacetylase 30404
Solute carrier family 22 member 60505
Histone deacetylase 40303
Guanine nucleotide-binding protein G3003
Histone deacetylase 10404
Histone deacetylase 70303
Histone deacetylase 20404
Polyamine deacetylase HDAC100202
Histone deacetylase 11 0303
Ataxin-2120012
Histone deacetylase 80303
Histone deacetylase 60303
Histone deacetylase 90202
Histone deacetylase 50303
ATP-dependent phosphofructokinase5005
thioredoxin reductase160016
ATAD5 protein, partial5005
TDP1 protein200020
estrogen-related nuclear receptor alpha200020
lamin isoform A-delta10140014
neuropeptide S receptor isoform A3003
Chain A, MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASE3003
Chain A, TYROSYL-DNA PHOSPHODIESTERASE4004
Chain A, Phospholipase A2 isoform 30011
Chain A, HADH2 protein4004
Chain B, HADH2 protein4004
GTP-binding protein (rab7)0011
ras protein, partial0011
interleukin 82002
GLS protein9009
aldehyde dehydrogenase 1 family, member A19009
thyroid stimulating hormone receptor110011
hypothetical protein, conserved1001
cytochrome P450 family 3 subfamily A polypeptide 4120012
EWS/FLI fusion protein120012
cytochrome P450 2D6100010
glucocerebrosidase3003
peroxisome proliferator-activated receptor delta9009
Rac1 protein0011
IDH15005
cell division cycle 42 (GTP binding protein, 25kDa), partial0011
15-hydroxyprostaglandin dehydrogenase [NAD(+)] isoform 14004
DNA polymerase iota isoform a (long)3003
DNA polymerase kappa isoform 14004
lethal factor (plasmid)5005
Prostaglandin-H2 D-isomerase0101
ATP-binding cassette sub-family C member 3013013
Multidrug resistance-associated protein 4013014
Prostaglandin G/H synthase 1 0101
Prostaglandin G/H synthase 2 0101
Bile salt export pump018018
Epidermal growth factor receptor0202
Carbonic anhydrase 10607
Carbonic anhydrase 20607
Fatty acid-binding protein, liver0101
Integrin beta-35117
Myeloperoxidase0101
Prostaglandin G/H synthase 10101
Seed linoleate 13S-lipoxygenase-10101
Integrin alpha-IIb5117
Glutathione hydrolase 1 proenzyme0101
Prostaglandin G/H synthase 10404
Adenosine receptor A10405
Adenosine receptor A2a0305
Substance-P receptor0101
Prostaglandin G/H synthase 20404
Urotensin-2 receptor0101
4-aminobutyrate aminotransferase, mitochondrial0101
Nuclear receptor ROR-gamma1001
Ras-related protein Rab-2A0011
Gamma-aminobutyric acid receptor subunit alpha-147112
Prostaglandin G/H synthase 20101
Rho-associated protein kinase 20101
Nicotinate phosphoribosyltransferase0202
Solute carrier family 22 member 200303
Solute carrier family 22 member 60303
Canalicular multispecific organic anion transporter 1012012
Sigma non-opioid intracellular receptor 10819
Sigma non-opioid intracellular receptor 10314
cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a130013
Platelet-activating factor receptor0101
Spike glycoprotein81211
ATPase family AAA domain-containing protein 58008
Chain A, Glycogen Phosphorylase0101
Chain A, Glycogen phosphorylase, liver form0011
Chain A, glycogen phosphorylase, liver form0011
Chain A, Glycogen phosphorylase, liver form0011
Chain A, Glycogen phosphorylase, liver form0011
Chain A, Chitinase0101
GLI family zinc finger 3140014
nuclear receptor subfamily 1, group I, member 3130013
pregnane X nuclear receptor100010
thyroid stimulating hormone receptor6006
v-jun sarcoma virus 17 oncogene homolog (avian)8008
atrial natriuretic peptide receptor 1 precursor2002
chromobox protein homolog 19009
DNA polymerase beta2002
nuclear factor erythroid 2-related factor 2 isoform 1180018
nuclear receptor ROR-gamma isoform 18008
Voltage-dependent calcium channel gamma-2 subunit8008
Potassium channel subfamily K member 20011
Glycogen phosphorylase, muscle form0101
Renin0101
Cholinesterase0101
Glycogen phosphorylase, liver form0101
Glycogen phosphorylase, muscle form0101
Replicase polyprotein 1ab0224
Adenosine receptor A30303
Replicase polyprotein 1ab0224
Glutamate receptor 282111
Amine oxidase [flavin-containing] A0101
Acetylcholinesterase0404
Amine oxidase [flavin-containing] B0202
cAMP-specific 3',5'-cyclic phosphodiesterase 4A0101
Adenosine receptor A30101
Adenosine receptor A2a0416
Adenosine receptor A2b0102
Adenosine receptor A2b0203
Adenosine receptor A10316
Vasopressin V2 receptor0001
Serine/threonine-protein kinase mTOR0202
Adenosine receptor A2a0101
Adenosine receptor A10101
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform 0101
DNA-dependent protein kinase catalytic subunit0101
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B0101
Adenylate cyclase type 10113
Chitotriosidase-10101
Serine-protein kinase ATM0101
Serine/threonine-protein kinase ATR0101
Adenosine receptor A2b0102
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C0101
Palmitoleoyl-protein carboxylesterase NOTUM0123
Endochitinase B10101
Muscarinic acetylcholine receptor0001
Phosphodiesterase 0101
Broad substrate specificity ATP-binding cassette transporter ABCG20101
Guanine deaminase0101
Chain A, Putative fructose-1,6-bisphosphate aldolase2002
Luciferase5005
Smad32002
apical membrane antigen 1, AMA13003
vitamin D3 receptor isoform VDRA6006
peptidyl-prolyl cis-trans isomerase NIMA-interacting 13003
Solute carrier family 15 member 10202
Solute carrier family 22 member 60303
Solute carrier family 22 member 80303
Solute carrier family 22 member 110202
Solute carrier family 22 member 80202
Beta-lactamase 0001
Beta-lactamase 0001
Beta-lactamase 0001
Beta-lactamase 0001
Beta-lactamase 0001
Beta-lactamase 0101
Beta-lactamase 0001
Metallo-beta-lactamase type 20001
Metallo-beta-lactamase VIM-11 0001
Beta-lactamase 0001
Metallo-beta-lactamase VIM-20001
Beta-lactamase 0001
Metallo-beta-lactamase VIM-19 0001
Beta-lactamase 0001
Beta-lactamase 0001
Metallo-beta-lactamase0001
Beta-lactamase 0101
Albumin0134
Beta-lactamase SHV-10001
Beta-lactamase SHV-10001
Beta-lactamase0001
Kappa-type opioid receptor0203
B2 metallo-beta-lactamase 0001
Beta-lactamase 0001
Beta-lactamase 0001
Beta-lactamase 0001
Solute carrier family 15 member 20101
Metallo-beta-lactamase VIM-130102
Beta-lactamase 0001
Beta-lactamase 0001
Beta-lactamase 0001
Metallo-beta-lactamase VIM-20001
Beta-lactamase 0001
Beta-lactamase Toho-10001
Beta-lactamase 0001
Solute carrier family 22 member 70102
Metallo-beta-lactamase0001
Solute carrier family 15 member 20101
Beta-lactamase 0001
Beta-lactamase 0001
Metallo-b-lactamase 0001
BlaVIM-1 0001
Beta-lactamase 0001
Beta-lactamase 0001
Beta-lactamase 0001
Carbapenem-hydrolyzing beta-lactamase KPC0001
Histamine H3 receptor0001
Beta-lactamase class B VIM-2 0001
Beta-lactamase VIM-1 0102
Solute carrier family 22 member 70101
PPM1D protein3003
glucose-6-phosphate dehydrogenase-6-phosphogluconolactonase0101
Spike glycoprotein0123
Replicase polyprotein 1ab0123
glucose-6-phosphate 1-dehydrogenase isoform b0101
Transmembrane protease serine 20123
Dihydrofolate reductase 0202
DNA ligase0101
Interferon beta9009
Riboflavin-binding protein0011
Major prion protein0011
Amyloid-beta precursor protein0404
Histidine-rich protein PFHRP-II0102
Procathepsin L0123
Muscarinic acetylcholine receptor M20718
Muscarinic acetylcholine receptor M40718
Cytochrome P450 3A40719
Muscarinic acetylcholine receptor M50707
Alpha-2A adrenergic receptor0718
Replicase polyprotein 1a0123
Replicase polyprotein 1ab0123
Spike glycoprotein0101
Muscarinic acetylcholine receptor M10718
Ribosyldihydronicotinamide dehydrogenase [quinone]0101
Alpha-2B adrenergic receptor0707
Alpha-2C adrenergic receptor0505
DNA ligase 10101
Muscarinic acetylcholine receptor M30718
Nuclear receptor subfamily 4 group A member 20022
Beta-secretase 10101
Calcium-dependent protein kinase 10011
MO15-related protein kinase Pfmrk 0101
DNA ligase A0101
Potassium voltage-gated channel subfamily H member 2012012
Sigma intracellular receptor 20101
Phosphoethanolamine N-methyltransferase0101
Angiotensin-converting enzyme 2 0123
Cysteine proteinase falcipain 2a 0101
Cysteine proteinase falcipain 2a 0101
NPC intracellular cholesterol transporter 1 precursor3003
Solute carrier family 22 member 1 0303
Sodium-dependent noradrenaline transporter0101
5-hydroxytryptamine receptor 40808
Aldo-keto reductase family 1 member B10808
Tryptophan 5-hydroxylase 10101
Angiotensin-converting enzyme0606
Aldo-keto reductase family 1 member B10202
Aromatase0101
Sodium-dependent noradrenaline transporter 0808
Sodium-dependent dopamine transporter0314
Alpha-1D adrenergic receptor0808
5-hydroxytryptamine receptor 2C0819
Histamine H1 receptor06210
5-hydroxytryptamine receptor 2B0819
5-hydroxytryptamine receptor 70202
Sodium-dependent dopamine transporter 0606
Sigma intracellular receptor 20101
Sodium-dependent serotonin transporter0101
Sodium-dependent dopamine transporter0101
Nuclear receptor subfamily 3 group C member 3 0606
Transporter0303
Protein-arginine deiminase type-40303
5-hydroxytryptamine receptor 3E0101
hypoxia-inducible factor 1 alpha subunit7007
Fumarate hydratase2002
caspase 7, apoptosis-related cysteine protease2002
estrogen receptor 2 (ER beta)9009
progesterone receptor8008
G7007
polyprotein2002
Beta-1 adrenergic receptor 0101
bromodomain adjacent to zinc finger domain 2B4004
caspase-32002
Adenylate cyclase type 1 0101
Histone H2A.x6006
cytochrome P450 2D6 isoform 14004
peripheral myelin protein 22 isoform 12002
cytochrome P450 2C19 precursor2002
cytochrome P450 2C9 precursor2002
potassium voltage-gated channel subfamily H member 2 isoform d2002
mitogen-activated protein kinase 12002
atrial natriuretic peptide receptor 2 precursor2002
short transient receptor potential channel 6 isoform 10011
cytochrome P450 3A4 isoform 14004
M-phase phosphoprotein 83003
transient receptor potential cation channel subfamily V member 11001
Gamma-aminobutyric acid receptor subunit pi46010
Polyunsaturated fatty acid lipoxygenase ALOX15B5005
Voltage-dependent L-type calcium channel subunit alpha-1F0303
Bile salt export pump0202
5-hydroxytryptamine receptor 3A0101
5-hydroxytryptamine receptor 3B0101
HLA class I histocompatibility antigen, B alpha chain 7007
Albumin0011
ATP-dependent translocase ABCB10517
Muscarinic acetylcholine receptor M10303
Muscarinic acetylcholine receptor M30303
Muscarinic acetylcholine receptor M40303
5-hydroxytryptamine receptor 1A0303
Muscarinic acetylcholine receptor M50303
Calmodulin-10101
Beta-2 adrenergic receptor0202
Cytochrome P450 2D60305
Muscarinic acetylcholine receptor M20404
Cytochrome P450 2C9 0506
D(2) dopamine receptor0407
Gamma-aminobutyric acid receptor subunit beta-146010
Alpha-1B adrenergic receptor0415
Beta-1 adrenergic receptor0202
Gamma-aminobutyric acid receptor subunit delta46010
Gamma-aminobutyric acid receptor subunit gamma-246111
D0202
D(3) dopamine receptor0202
Alpha-2B adrenergic receptor0213
Gamma-aminobutyric acid receptor subunit alpha-546010
Gamma-aminobutyric acid receptor subunit alpha-346010
D(2) dopamine receptor0202
Endothelin receptor type B0101
D(1A) dopamine receptor0607
D(4) dopamine receptor0406
D(1B) dopamine receptor0102
Adenylate cyclase type 30101
Alpha-2C adrenergic receptor0213
UDP-glucuronosyltransferase 1A40002
Alpha-2A adrenergic receptor0213
Gamma-aminobutyric acid receptor subunit gamma-146010
Gamma-aminobutyric acid receptor subunit alpha-246010
Alpha-1D adrenergic receptor0213
5-hydroxytryptamine receptor 3A0101
Endothelin receptor type B0101
Histamine H2 receptor0606
D(1B) dopamine receptor0202
Beta-3 adrenergic receptor0101
Adenylate cyclase type 20112
Adenylate cyclase type 40101
5-hydroxytryptamine receptor 2A0608
Gamma-aminobutyric acid receptor subunit alpha-446010
Gamma-aminobutyric acid receptor subunit gamma-346010
Gamma-aminobutyric acid receptor subunit alpha-646010
D(4) dopamine receptor0202
Histamine H1 receptor0101
Histamine H1 receptor0303
Cytochrome P450 2C190203
5-hydroxytryptamine receptor 2C 0101
5-hydroxytryptamine receptor 70101
Alpha-1A adrenergic receptor0101
5-hydroxytryptamine receptor 2A0101
Alpha-1B adrenergic receptor0101
D(3) dopamine receptor0608
Adenylate cyclase type 80101
Alpha-1A adrenergic receptor0516
5-hydroxytryptamine receptor 3A0101
Histamine H2 receptor6108
5-hydroxytryptamine receptor 5A0101
5-hydroxytryptamine receptor 60607
Cytochrome P450 2J20304
3-hydroxy-3-methylglutaryl-coenzyme A reductase 0202
D(2) dopamine receptor0101
D(3) dopamine receptor0101
Gastrin/cholecystokinin type B receptor0101
D(2) dopamine receptor0101
D(2) dopamine receptor0202
Calmodulin 0011
Gamma-aminobutyric acid receptor subunit beta-346010
Gamma-aminobutyric acid receptor subunit beta-246111
Inositol monophosphatase 13003
Voltage-dependent L-type calcium channel subunit alpha-1D 0303
5-hydroxytryptamine receptor 2B0101
Adenylate cyclase type 60101
Adenylate cyclase type 50101
5-hydroxytryptamine receptor 40101
Voltage-dependent L-type calcium channel subunit alpha-1S0303
Voltage-dependent L-type calcium channel subunit alpha-1C0303
Transporter0101
Cholecystokinin receptor type A0101
5-hydroxytryptamine receptor 1A0101
5-hydroxytryptamine receptor 3D0101
Adenylyl cyclase 7 0101
5-hydroxytryptamine receptor 3C0101
GABA theta subunit46010
Inositol hexakisphosphate kinase 17007
D0202
Gamma-aminobutyric acid receptor subunit epsilon46010
Histamine H4 receptor0112
Histamine H3 receptor0101
cytochrome P450 2C9, partial7007
glp-1 receptor, partial4004
peroxisome proliferator activated receptor gamma100010
aryl hydrocarbon receptor6006
nuclear receptor subfamily 1, group I, member 22002
nuclear receptor subfamily 0 group B member 10101
steroidogenic factor 10101
histone-lysine N-methyltransferase 2A isoform 2 precursor2002
relaxin receptor 1 isoform 11001
relaxin receptor 2 isoform 11001
Nuclear receptor subfamily 1 group I member 20033
Rap guanine nucleotide exchange factor 32002
Cellular tumor antigen p53150015
Solute carrier family 2, facilitated glucose transporter member 10011
Adenylate cyclase type 80011
Relaxin receptor 10011
Nuclear receptor subfamily 1 group I member 20011
activating transcription factor 64004
B2 bradykinin receptor0101
Dihydrofolate reductase0001
Dihydrofolate reductase0101
Chymotrypsinogen A0001
Beta-lactamase0101
Beta-lactamase0001
Beta-galactosidase0102
Choline O-acetyltransferase0101
Ectonucleotide pyrophosphatase/phosphodiesterase family member 20202
PH domain leucine-rich repeat-containing protein phosphatase 20101
Chymotrypsin-C0101
Vasopressin V2 receptor0112
Oxytocin receptor0011
Vasopressin V1a receptor0112
Vasopressin V1b receptor0112
Translocator protein0101
Vasopressin V2 receptor 0112
Glutamate receptor ionotropic, NMDA 2D0202
Glutamate receptor ionotropic, NMDA 3B0202
Neuronal acetylcholine receptor subunit alpha-30101
Sodium channel protein type 1 subunit alpha0101
Sodium channel protein type 2 subunit alpha0202
Sodium channel protein type 3 subunit alpha0101
Cytochrome P450 2D10202
Cytochrome P450 2D260202
Neuronal acetylcholine receptor subunit beta-40101
Cytochrome P450 2D30202
Glutamate receptor ionotropic, NMDA 1 0314
Taste receptor type 2 member 460011
Glutamate receptor ionotropic, NMDA 2A 0314
Glutamate receptor ionotropic, NMDA 2B0314
Glutamate receptor ionotropic, NMDA 2C0314
Glutamate receptor ionotropic, NMDA 10202
Glutamate receptor ionotropic, NMDA 2A0202
Glutamate receptor ionotropic, NMDA 2B0202
Glutamate receptor ionotropic, NMDA 2C0202
Sigma non-opioid intracellular receptor 10303
Glutamate receptor ionotropic, NMDA 2D0314
Cytochrome P450 2D40202
Glutamate receptor ionotropic, NMDA 3A0202
Glutamate receptor ionotropic, NMDA 3B0314
Glutamate receptor ionotropic, NMDA 3A0314
Eyes absent homolog 20101
Angiotensin-converting enzyme 0101
Beta-lactamase 0101
Beta-lactamase 0101
Voltage-dependent T-type calcium channel subunit alpha-1I0101
cellular tumor antigen p53 isoform a5005
Endolysin0022
Steroid 17-alpha-hydroxylase/17,20 lyase0101
Aromatase0202
Cytochrome P450 11B1, mitochondrial0101
Cytochrome P450 11B2, mitochondrial0101
Cytochrome P450 11B2, mitochondrial0101
Cytochrome P450 11B2, mitochondrial0101
nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105), isoform CRA_a4004
thioredoxin glutathione reductase1001
ubiquitin carboxyl-terminal hydrolase 2 isoform a1001
Voltage-dependent calcium channel subunit alpha-2/delta-10101
Chain A, Ferritin light chain5005
Gamma-aminobutyric acid 0112
Gamma-aminobutyric acid receptor subunit rho-30011
Hsf1 protein0023
transcriptional regulator ERG isoform 33003
histone acetyltransferase KAT2A isoform 13003
Gamma-aminobutyric acid receptor subunit pi0202
Gamma-aminobutyric acid receptor subunit delta0202
Gamma-aminobutyric acid type B receptor subunit 20011
Gamma-aminobutyric acid type B receptor subunit 20101
Gamma-aminobutyric acid receptor subunit alpha-10325
Gamma-aminobutyric acid receptor subunit alpha-60112
Gamma-aminobutyric acid receptor subunit beta-10314
Gamma-aminobutyric acid receptor subunit gamma-20325
Gamma-aminobutyric acid receptor subunit gamma-20112
Gamma-aminobutyric acid receptor subunit delta0112
Sodium- and chloride-dependent GABA transporter 10101
Gamma-aminobutyric acid receptor subunit rho-10022
Gamma-aminobutyric acid receptor subunit alpha-20112
Gamma-aminobutyric acid receptor subunit alpha-30112
Gamma-aminobutyric acid receptor subunit gamma-30112
Gamma-aminobutyric acid receptor subunit beta-30314
Gamma-aminobutyric acid receptor subunit rho-20011
Sodium- and chloride-dependent GABA transporter 10101
Sodium- and chloride-dependent taurine transporter0101
Gamma-aminobutyric acid receptor subunit alpha-50325
Sodium- and chloride-dependent GABA transporter 20101
Sodium- and chloride-dependent GABA transporter 30101
Sodium- and chloride-dependent GABA transporter 10202
Sodium- and chloride-dependent GABA transporter 20202
Sodium- and chloride-dependent GABA transporter 30202
Gamma-aminobutyric acid receptor subunit alpha-30325
Gamma-aminobutyric acid receptor subunit alpha-20325
Gamma-aminobutyric acid receptor subunit beta-20325
Sodium- and chloride-dependent betaine transporter0101
Sodium- and chloride-dependent betaine transporter0101
Sodium- and chloride-dependent GABA transporter 30101
Gamma-aminobutyric acid receptor subunit alpha-40314
Gamma-aminobutyric acid receptor subunit beta-10112
Gamma-aminobutyric acid receptor subunit alpha-10112
Gamma-aminobutyric acid receptor subunit beta-30112
Gamma-aminobutyric acid receptor subunit epsilon0202
4-aminobutyrate aminotransferase, mitochondrial0001
4-aminobutyrate aminotransferase, mitochondrial0001
TAR DNA-binding protein 434004
Gamma-aminobutyric acid receptor subunit alpha-60314
Sterol O-acyltransferase 10011
Proton-coupled amino acid transporter 10101
Gamma-aminobutyric acid receptor subunit alpha-50112
Gamma-aminobutyric acid receptor subunit gamma-10202
Gamma-aminobutyric acid receptor subunit pi0112
Gamma-aminobutyric acid receptor subunit gamma-30202
Gamma-aminobutyric acid receptor subunit alpha-40112
Platelet glycoprotein VI0011
Gamma-aminobutyric acid receptor subunit theta0112
Sodium- and chloride-dependent GABA transporter 20101
Gamma-aminobutyric acid receptor subunit gamma-10112
Gamma-aminobutyric acid type B receptor subunit 10011
Gamma-aminobutyric acid receptor subunit theta0202
Gamma-aminobutyric acid type B receptor subunit 10101
Chain A, GLUTAMATE RECEPTOR SUBUNIT 20101
Chain A, Glutamate Receptor Subunit 20101
Chain B, Glutamate Receptor Subunit 20101
Chain A, Slr1257 protein0011
Chain A, Glucosamine--fructose-6-phosphate aminotransferase [isomerizing]0101
beta-2 adrenergic receptor2002
Metabotropic glutamate receptor 80202
Metabotropic glutamate receptor 60113
Excitatory amino acid transporter 40101
Glutathione reductase, mitochondrial0202
Bifunctional aspartokinase/homoserine dehydrogenase 10101
Prothrombin0011
ATP-citrate synthase 0101
Glutamate receptor 10213
Glutamate receptor 30213
Glutamate receptor 40213
Glutamate receptor ionotropic, kainate 10213
Metabotropic glutamate receptor 10112
Metabotropic glutamate receptor 20011
Metabotropic glutamate receptor 30011
Metabotropic glutamate receptor 40112
Metabotropic glutamate receptor 50011
Metabotropic glutamate receptor 60011
Metabotropic glutamate receptor 70011
Glutamate receptor ionotropic, kainate 10112
Metabotropic glutamate receptor 50113
Glutamate receptor ionotropic, kainate 20213
Glutamate receptor 10213
Glutamate receptor 20213
Glutamate receptor 30112
Glutamate receptor ionotropic, kainate 30202
Excitatory amino acid transporter 10203
Excitatory amino acid transporter 20203
Excitatory amino acid transporter 30203
Metabotropic glutamate receptor 80011
Glutamate receptor 40213
Excitatory amino acid transporter 3 0001
Glutamate racemase0001
Metabotropic glutamate receptor 80112
Fatty-acid amide hydrolase 10101
Glutamate receptor ionotropic, kainate 40202
Glutamate carboxypeptidase 20101
Glutamate receptor ionotropic, kainate 20112
Glutamate receptor ionotropic, kainate 30101
Metabotropic glutamate receptor 10113
Metabotropic glutamate receptor 20113
Metabotropic glutamate receptor 70113
Metabotropic glutamate receptor 30113
Metabotropic glutamate receptor 40113
Glutamate receptor ionotropic, kainate 50101
Carbonic anhydrase-like protein, putative0001
Glutamate receptor ionotropic, kainate 50202
Glutamate racemase0001
Prolyl 4-hydroxylase0202
Alpha-ketoglutarate-dependent dioxygenase FTO0202
Chain B, EUKARYOTIC TRANSLATION INITIATION FACTOR 4E0011
Carbonic anhydrase 0101
Carbonic anhydrase0101
Carbonic anhydrase 40202
Carbonic anhydrase 60202
Carbonic anhydrase 5A, mitochondrial0202
Carbonic anhydrase0101
Carbonic anhydrase 70202
Carbonic anhydrase 90202
Carbonic anhydrase, alpha family 0101
Carbonic anhydrase0101
Carbonic anhydrase 130202
Carbonic anhydrase 5B, mitochondrial0202
Neuronal acetylcholine receptor subunit beta-20101
Neuronal acetylcholine receptor subunit alpha-70101
chaperonin-containing TCP-1 beta subunit homolog2002
Synaptic vesicle glycoprotein 2A0202
Thioredoxin reductase 0101
muscleblind-like protein 1 isoform 11001
Flavodoxin0001
Lanosterol 14-alpha demethylase0101
Stromelysin-10112
Matrilysin0101
Multidrug transporter MdfA0101
Matrix metalloproteinase-90101
Protein mono-ADP-ribosyltransferase PARP150101
Nuclear receptor corepressor 10101
Integrin beta-10101
Leukotriene A-4 hydrolase0101
Integrin alpha-40101
Nuclear receptor corepressor 20101
Opioid receptor, delta 1b 0101
Acetylcholinesterase0101
Opioid receptor homologue0101
ATP-dependent translocase ABCB10101
Acyl-CoA desaturase 10101
Translocator protein0112
Histidine decarboxylase0011
ATP-dependent translocase ABCB10101
Proteinase-activated receptor 10112
Delta-type opioid receptor0102
Delta-type opioid receptor0214
Kappa-type opioid receptor0214
Mu-type opioid receptor0216
Kappa-type opioid receptor0214
Mu-type opioid receptor0416
UDP-glucuronosyltransferase 1A30001
Delta-type opioid receptor0416
Kappa-type opioid receptor0416
Mu-type opioid receptor0215
Nociceptin receptor0101
Mu-type opioid receptor0101
Mu-type opioid receptor0202
Beta-2 adrenergic receptor0101
Mas-related G-protein coupled receptor member X20011
Mu-type opioid receptor0101
67.9K protein3003
heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)3003
huntingtin isoform 21001
ras-related protein Rab-9A2002
serine/threonine-protein kinase mTOR isoform 12002
Cytochrome P450 2C80101
Sodium- and chloride-dependent betaine transporter0101
D(1A) dopamine receptor2002
Voltage-dependent N-type calcium channel subunit alpha-1B0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Pyruvate kinase, M2 isozyme0101
Chain A, Phosphonopyruvate hydrolase0101
Chain A, Phosphoenolpyruvate-protein phosphotransferase0101
Proto-oncogene tyrosine-protein kinase Src0101
Tyrosine-protein phosphatase non-receptor type 10204
Sodium channel protein type 1 subunit alpha0202
Sodium channel protein type 2 subunit alpha0202
Sodium channel protein type 3 subunit alpha0202
GALC protein1001
hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)1001
lysosomal alpha-glucosidase preproprotein1001
mu-type opioid receptor isoform MOR-10011
Vpr1001
5-hydroxytryptamine receptor 2A0011
Neuronal acetylcholine receptor subunit alpha-41001
Neuronal acetylcholine receptor subunit beta-21001
endonuclease IV1001
parathyroid hormone/parathyroid hormone-related peptide receptor precursor1001
Voltage-dependent L-type calcium channel subunit alpha-1C0101
Sodium channel protein type 4 subunit alpha0102
Sodium channel protein type 5 subunit alpha0101
Sodium channel protein type 9 subunit alpha0101
Chain A, Beta-lactamase4004
SMAD family member 23003
SMAD family member 33003
nonstructural protein 11001
heat shock protein HSP 90-alpha isoform 20001
heat shock protein 90, putative0001
Monocarboxylate transporter 40001
Monocarboxylate transporter 20001
Monocarboxylate transporter 10001
C-terminal-binding protein 20101
Monocarboxylate transporter 20101
Solute carrier organic anion transporter family member 2A10101
Estrogen receptor beta0001
Inhibitor of nuclear factor kappa-B kinase subunit beta0001
Polyphenol oxidase 20102
Carbonic anhydrase 120101
5'-AMP-activated protein kinase subunit beta-20001
Polymerase acidic protein0011
Carbonic anhydrase 30101
Tyrosine-protein phosphatase YopH0101
High mobility group protein B10011
Aldo-keto reductase family 1 member B10101
Prolyl 4-hydroxylase subunit alpha-10101
Estrogen receptor0001
Cystathionine gamma-lyase0101
5'-AMP-activated protein kinase subunit gamma-10001
5'-AMP-activated protein kinase catalytic subunit alpha-20001
Xanthine dehydrogenase/oxidase0101
5'-AMP-activated protein kinase catalytic subunit alpha-10001
Carbonic anhydrase0101
Ubiquitin-like domain-containing CTD phosphatase 10101
Carbonic anhydrase 150101
5'-AMP-activated protein kinase subunit gamma-30001
5'-AMP-activated protein kinase subunit gamma-20001
Carbonic anhydrase 140101
5'-AMP-activated protein kinase subunit beta-10001
PINK11001
Parkin1001
photoreceptor-specific nuclear receptor0101
nuclear factor erythroid 2-related factor 2 isoform 21001
serine/threonine-protein kinase PLK12002
urokinase-type plasminogen activator precursor1001
plasminogen precursor1001
urokinase plasminogen activator surface receptor precursor1001
transactivating tegument protein VP16 [Human herpesvirus 1]0101
DNA dC->dU-editing enzyme APOBEC-3G isoform 11001
3-hydroxy-3-methylglutaryl-coenzyme A reductase0202
Insulin receptor 0101
3-hydroxy-3-methylglutaryl-coenzyme A reductase0101
Solute carrier organic anion transporter family member 1B10102
Chain A, Acetylcholinesterase0011
Chain A, Acetylcholinesterase0011
Chain A, Acetylcholinesterase0011
Chain A, Acetylcholinesterase0011
Chain A, Acetylcholinesterase0011
Chain A, Acetylcholinesterase0011
Chain A, Acetylcholinesterase0011
Acetylcholinesterase0101
Chain A, CES1 protein0101
DNA polymerase III, partial1001
thyrotropin-releasing hormone receptor1001
Caspase-71001
interferon gamma precursor0001
caspase-31001
ubiquitin-conjugating enzyme E2 N0101
streptokinase A precursor0011
Serine/threonine-protein kinase D30112
Estrogen receptor0214
Lysosomal acid glucosylceramidase0011
Receptor tyrosine-protein kinase erbB-20101
Protein kinase C gamma type0213
Protein kinase C alpha type0101
Protein kinase C beta type0213
Estrogen receptor0012
Tyrosine-protein kinase Lck0101
Tyrosine-protein kinase Fyn0101
Progesterone receptor0101
Beta-1 adrenergic receptor0202
Protein kinase C delta type0101
Protein kinase C epsilon type0101
Protein kinase C zeta type0101
Polyunsaturated fatty acid 5-lipoxygenase0101
Steroid hormone receptor ERR10101
Transcriptional activator protein LuxR0101
Beta-3 adrenergic receptor0202
Androgen receptor0202
Protein kinase C alpha type0213
Cytochrome P450 2B60101
Substance-K receptor0202
Thromboxane-A synthase 0101
Protein kinase C eta type0112
Substance-P receptor0202
B2 bradykinin receptor0202
Melanocortin receptor 40202
C-8 sterol isomerase0101
Melanocortin receptor 50202
Alpha-synuclein1001
Protein kinase C iota type0112
Melanocortin receptor 30202
Estrogen-related receptor gamma0101
Protein kinase C gamma type0101
Protein kinase C beta type0101
Phospholipase D1 0101
Protein kinase C epsilon type0213
Protein kinase C theta type0112
Protein kinase C zeta type0112
Protein kinase C delta type0213
Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform0101
Platelet-activating factor acetylhydrolase0101
Phospholipase D10101
3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase0213
Serine/threonine-protein kinase D10112
Estrogen receptor beta0012
Protein kinase C eta type0101
Estrogen receptor beta0213
Emopamil-binding protein-like0101
7-dehydrocholesterol reductase0112
Protein kinase C theta type0101
Luciferin 4-monooxygenase0011
Ras guanyl-releasing protein 30011
Chain X, Thyroid hormone receptor beta-10011
Chain X, Thyroid hormone receptor beta-10011
DNA polymerase eta isoform 11001
Solute carrier organic anion transporter family member 1A40001
Solute carrier organic anion transporter family member 1A50001
Transthyretin0102
Thyroid hormone receptor alpha0011
Thyroid hormone receptor beta0011
Proliferating cell nuclear antigen0101
Retinoic acid receptor RXR-alpha0022
UDP-glucuronosyltransferase 1A1 0101
Peroxisome proliferator-activated receptor gamma0022
Malate dehydrogenase, mitochondrial0101
Solute carrier organic anion transporter family member 1A20001
Solute carrier organic anion transporter family member 1A30001
Solute carrier organic anion transporter family member 4C10101
Monocarboxylate transporter 80001
Bile acid receptor0101
Solute carrier organic anion transporter family member 1C10001
polyunsaturated fatty acid lipoxygenase ALOX121001
Chain A, PLASMINOGEN0011
Chain A, PLASMINOGEN0011
Plasminogen0213
Urokinase-type plasminogen activator0101
acid sphingomyelinase1001
HLA class I histocompatibility antigen, A alpha chain 0011
Neuronal acetylcholine receptor subunit alpha-70101
Sphingosine-1-phosphate lyase 10101
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]