Brain Injuries, Penetrating

Head injuries which feature compromise of the skull and dura mater. These may result from gunshot wounds (WOUNDS, GUNSHOT), stab wounds (WOUNDS, STAB), and other forms of trauma.

Synonyms(9)

Synonym
Head Trauma, Penetrating
Craniocerebral Trauma, Penetrating
Missile Injuries, Penetrating, Head
Head Injuries, Penetrating, Missile
Brain Injuries, Penetrating
Penetrating Missile Injuries, Head
Head Injuries, Penetrating
Cranial Trauma, Penetrating
Head Injury, Penetrating

Research Excerpts

Overview

Excerpt	Reference
"Although penetrating head injuries are very rare in Japan, an extremely rare case is reported in which an ivory chip, embedded in the subcutaneous tissue by a cosmetic rhinoplasty, penetrated the cranium."	( Aishima, K; Hara, T; Inoue, M; Matsubayashi, S; Miyahara, M; Ohno, H; Okamoto, K; Tamai, Y, 2016)
"Transnasal penetrating brain injuries are rare and a medical emergency, which needs to be treated promptly."	( Alataş, N; Güllüev, M; Yücel, A; Yücel, H, 2018)

Treatment

Excerpt	Reference
"We present here a case of penetrating head injury caused by stabbing a scissor in head by a local witch doctor in order to treat a psychiatric ailment."	( Kumar, A; Pandey, R; Sharma, V; Singh, K, 2011)
"Transnasal penetrating brain injuries are rare and a medical emergency, which needs to be treated promptly."	( Alataş, N; Güllüev, M; Yücel, A; Yücel, H, 2018)
"Although the immediate treatment of penetrating head injury is needed, surgical strategies are varied based on the trajectory of the penetrating objects in the cranium."	( Fujii, Y; Hanaoka, Y; Horiuchi, T; Kurokawa, T; Ogihara, N; Yako, T; Yamazaki, D, 2023)

Research

Studies (179)

Timeframe	Studies, This Condition (%)	All Conditions %
pre-1990	0 (0.00)	23.3326
1990's	2 (1.12)	12.5806
2000's	68 (37.99)	18.1394
2010's	95 (53.07)	28.8240
2020's	14 (7.82)	9.53

Drug	Relationship Strength	Studies
gamma-aminobutyric acid	low	2
hydrochloric acid	low	1
salicylic acid	low	9
lactic acid	low	1
glycerol	low	2
methanol	low	11
oxalic acid	low	1
pyruvic acid	low	1
toluene	low	1
phenytoin	low	2
aspirin	low	1
brotizolam	low	1
caffeine	low	2
chloroquine	low	1
citalopram	low	1
dimercaprol	low	1
doxylamine	low	1
ethosuximide	low	1
gabapentin	low	2
isoflurane	low	1
metronidazole	low	1
apnea	low	1
nortriptyline	low	1
phenobarbital	low	1
piracetam	low	2
succinylcholine	low	1
tranexamic acid	low	2
edetic acid	low	1
isoprene	low	4
peracetic acid	low	1
ethylbenzene	low	1
thiophenes	low	1
trinitrotoluene	low	1
congo red	low	1
acetylcysteine	low	1
titanium	low	1
barium sulfate	low	1
tetradecanoylphorbol acetate	low	1
4-methoxyamphetamine	low	3
glutamic acid	low	1
cefazolin	low	1
propiconazole	low	53
colforsin	low	2
fenoxycarb	low	1
simvastatin	low	1
fadrozole	low	1
trazodone hydrochloride	low	1
fibrinogen	low	1
glucuronic acid	low	1
glycogen	low	1
fibrin	low	2
clindamycin	low	1
tamoxifen	low	2
phenylephrine hydrochloride	low	9
levetiracetam	low	2
morphine	low	1
deamino arginine vasopressin	low	2
lead	low	2
antimony	low	2
barium	low	2
aluminum	low	1
dextromethorphan	low	2
cefotaxime	low	1
mocetinostat	low	1
n-acetylcysteinamide	low	1
nnz 2566	low	2
technetium tc 99m exametazime	low	1
indocyanine green	low	1
mefloquine	low	2
protectin d1	low	1
cytochrome c-t	low	1
ro13-9904	low	1
heme	low	1
minocycline	low	1
calca protein, human	low	1
transforming growth factor beta	low	1
agar	low	2
xjb-5-131	low	1
exudates	low	1
clozapine	low	1

Protein Targets (886)

Protein	Potency Measurements	Inhibition Measurements	Activation Measurements	Drugs
5-hydroxytryptamine receptor 2C	0	4	1	5
5-hydroxytryptamine receptor 2A	0	4	1	6
5-hydroxytryptamine receptor 1A	0	10	1	11
5-hydroxytryptamine receptor 1B	0	7	1	8
5-hydroxytryptamine receptor 1D	0	4	1	5
5-hydroxytryptamine receptor 1F	0	4	1	5
5-hydroxytryptamine receptor 2B	0	4	2	6
5-hydroxytryptamine receptor 6	0	1	1	2
Sodium-dependent serotonin transporter	0	10	2	12
Sodium-dependent serotonin transporter	0	4	0	4
5-hydroxytryptamine receptor 7	0	2	1	3
5-hydroxytryptamine receptor 5A	0	1	1	2
5-hydroxytryptamine receptor 5B	0	1	1	2
5-hydroxytryptamine receptor 3A	0	2	1	3
5-hydroxytryptamine receptor 4	0	1	1	2
5-hydroxytryptamine receptor 3B	0	2	1	3
Chain A, JmjC domain-containing histone demethylation protein 3A	5	0	0	5
Chain A, 2-oxoglutarate Oxygenase	6	0	0	6
Chain A, ATP-DEPENDENT DNA HELICASE Q1	1	0	0	1
acetylcholinesterase	6	0	0	6
dopamine D1 receptor	2	0	0	2
15-lipoxygenase, partial	1	0	0	1
pregnane X receptor	4	0	0	4
phosphopantetheinyl transferase	6	0	0	6
RAR-related orphan receptor gamma	17	0	0	17
USP1 protein, partial	4	0	0	4
NFKB1 protein, partial	2	0	0	2
Microtubule-associated protein tau	6	0	0	6
Thrombopoietin	2	0	0	2
AR protein	25	0	0	25
regulator of G-protein signaling 4	7	0	0	7
glucocorticoid receptor [Homo sapiens]	19	0	0	19
retinoic acid nuclear receptor alpha variant 1	19	0	0	19
retinoid X nuclear receptor alpha	11	0	0	11
farnesoid X nuclear receptor	7	0	0	7
estrogen nuclear receptor alpha	27	0	0	27
vitamin D (1,25- dihydroxyvitamin D3) receptor	9	0	0	9
arylsulfatase A	9	0	0	9
euchromatic histone-lysine N-methyltransferase 2	21	0	0	21
Bloom syndrome protein isoform 1	9	0	0	9
D(1A) dopamine receptor	8	0	0	8
thyroid hormone receptor beta isoform a	9	0	0	9
thyroid hormone receptor beta isoform 2	16	0	0	16
heat shock protein beta-1	3	0	0	3
flap endonuclease 1	6	0	0	6
geminin	14	0	0	14
peripheral myelin protein 22	8	0	0	8
survival motor neuron protein isoform d	5	0	0	5
muscarinic acetylcholine receptor M1	8	0	0	8
Histone deacetylase 3	0	4	0	4
Solute carrier family 22 member 6	0	5	0	5
Histone deacetylase 4	0	3	0	3
Guanine nucleotide-binding protein G	3	0	0	3
Histone deacetylase 1	0	4	0	4
Histone deacetylase 7	0	3	0	3
Histone deacetylase 2	0	4	0	4
Polyamine deacetylase HDAC10	0	2	0	2
Histone deacetylase 11	0	3	0	3
Ataxin-2	12	0	0	12
Histone deacetylase 8	0	3	0	3
Histone deacetylase 6	0	3	0	3
Histone deacetylase 9	0	2	0	2
Histone deacetylase 5	0	3	0	3
ATP-dependent phosphofructokinase	5	0	0	5
thioredoxin reductase	16	0	0	16
ATAD5 protein, partial	5	0	0	5
TDP1 protein	20	0	0	20
estrogen-related nuclear receptor alpha	20	0	0	20
lamin isoform A-delta10	14	0	0	14
neuropeptide S receptor isoform A	3	0	0	3
Chain A, MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASE	3	0	0	3
Chain A, TYROSYL-DNA PHOSPHODIESTERASE	4	0	0	4
Chain A, Phospholipase A2 isoform 3	0	0	1	1
Chain A, HADH2 protein	4	0	0	4
Chain B, HADH2 protein	4	0	0	4
GTP-binding protein (rab7)	0	0	1	1
ras protein, partial	0	0	1	1
interleukin 8	2	0	0	2
GLS protein	9	0	0	9
aldehyde dehydrogenase 1 family, member A1	9	0	0	9
thyroid stimulating hormone receptor	11	0	0	11
hypothetical protein, conserved	1	0	0	1
cytochrome P450 family 3 subfamily A polypeptide 4	12	0	0	12
EWS/FLI fusion protein	12	0	0	12
cytochrome P450 2D6	10	0	0	10
glucocerebrosidase	3	0	0	3
peroxisome proliferator-activated receptor delta	9	0	0	9
Rac1 protein	0	0	1	1
IDH1	5	0	0	5
cell division cycle 42 (GTP binding protein, 25kDa), partial	0	0	1	1
15-hydroxyprostaglandin dehydrogenase [NAD(+)] isoform 1	4	0	0	4
DNA polymerase iota isoform a (long)	3	0	0	3
DNA polymerase kappa isoform 1	4	0	0	4
lethal factor (plasmid)	5	0	0	5
Prostaglandin-H2 D-isomerase	0	1	0	1
ATP-binding cassette sub-family C member 3	0	13	0	13
Multidrug resistance-associated protein 4	0	13	0	14
Prostaglandin G/H synthase 1	0	1	0	1
Prostaglandin G/H synthase 2	0	1	0	1
Bile salt export pump	0	18	0	18
Epidermal growth factor receptor	0	2	0	2
Carbonic anhydrase 1	0	6	0	7
Carbonic anhydrase 2	0	6	0	7
Fatty acid-binding protein, liver	0	1	0	1
Integrin beta-3	5	1	1	7
Myeloperoxidase	0	1	0	1
Prostaglandin G/H synthase 1	0	1	0	1
Seed linoleate 13S-lipoxygenase-1	0	1	0	1
Integrin alpha-IIb	5	1	1	7
Glutathione hydrolase 1 proenzyme	0	1	0	1
Prostaglandin G/H synthase 1	0	4	0	4
Adenosine receptor A1	0	4	0	5
Adenosine receptor A2a	0	3	0	5
Substance-P receptor	0	1	0	1
Prostaglandin G/H synthase 2	0	4	0	4
Urotensin-2 receptor	0	1	0	1
4-aminobutyrate aminotransferase, mitochondrial	0	1	0	1
Nuclear receptor ROR-gamma	1	0	0	1
Ras-related protein Rab-2A	0	0	1	1
Gamma-aminobutyric acid receptor subunit alpha-1	4	7	1	12
Prostaglandin G/H synthase 2	0	1	0	1
Rho-associated protein kinase 2	0	1	0	1
Nicotinate phosphoribosyltransferase	0	2	0	2
Solute carrier family 22 member 20	0	3	0	3
Solute carrier family 22 member 6	0	3	0	3
Canalicular multispecific organic anion transporter 1	0	12	0	12
Sigma non-opioid intracellular receptor 1	0	8	1	9
Sigma non-opioid intracellular receptor 1	0	3	1	4
cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a	13	0	0	13
Platelet-activating factor receptor	0	1	0	1
Spike glycoprotein	8	1	2	11
ATPase family AAA domain-containing protein 5	8	0	0	8
Chain A, Glycogen Phosphorylase	0	1	0	1
Chain A, Glycogen phosphorylase, liver form	0	0	1	1
Chain A, glycogen phosphorylase, liver form	0	0	1	1
Chain A, Glycogen phosphorylase, liver form	0	0	1	1
Chain A, Glycogen phosphorylase, liver form	0	0	1	1
Chain A, Chitinase	0	1	0	1
GLI family zinc finger 3	14	0	0	14
nuclear receptor subfamily 1, group I, member 3	13	0	0	13
pregnane X nuclear receptor	10	0	0	10
thyroid stimulating hormone receptor	6	0	0	6
v-jun sarcoma virus 17 oncogene homolog (avian)	8	0	0	8
atrial natriuretic peptide receptor 1 precursor	2	0	0	2
chromobox protein homolog 1	9	0	0	9
DNA polymerase beta	2	0	0	2
nuclear factor erythroid 2-related factor 2 isoform 1	18	0	0	18
nuclear receptor ROR-gamma isoform 1	8	0	0	8
Voltage-dependent calcium channel gamma-2 subunit	8	0	0	8
Potassium channel subfamily K member 2	0	0	1	1
Glycogen phosphorylase, muscle form	0	1	0	1
Renin	0	1	0	1
Cholinesterase	0	1	0	1
Glycogen phosphorylase, liver form	0	1	0	1
Glycogen phosphorylase, muscle form	0	1	0	1
Replicase polyprotein 1ab	0	2	2	4
Adenosine receptor A3	0	3	0	3
Replicase polyprotein 1ab	0	2	2	4
Glutamate receptor 2	8	2	1	11
Amine oxidase [flavin-containing] A	0	1	0	1
Acetylcholinesterase	0	4	0	4
Amine oxidase [flavin-containing] B	0	2	0	2
cAMP-specific 3',5'-cyclic phosphodiesterase 4A	0	1	0	1
Adenosine receptor A3	0	1	0	1
Adenosine receptor A2a	0	4	1	6
Adenosine receptor A2b	0	1	0	2
Adenosine receptor A2b	0	2	0	3
Adenosine receptor A1	0	3	1	6
Vasopressin V2 receptor	0	0	0	1
Serine/threonine-protein kinase mTOR	0	2	0	2
Adenosine receptor A2a	0	1	0	1
Adenosine receptor A1	0	1	0	1
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform	0	1	0	1
DNA-dependent protein kinase catalytic subunit	0	1	0	1
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B	0	1	0	1
Adenylate cyclase type 1	0	1	1	3
Chitotriosidase-1	0	1	0	1
Serine-protein kinase ATM	0	1	0	1
Serine/threonine-protein kinase ATR	0	1	0	1
Adenosine receptor A2b	0	1	0	2
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C	0	1	0	1
Palmitoleoyl-protein carboxylesterase NOTUM	0	1	2	3
Endochitinase B1	0	1	0	1
Muscarinic acetylcholine receptor	0	0	0	1
Phosphodiesterase	0	1	0	1
Broad substrate specificity ATP-binding cassette transporter ABCG2	0	1	0	1
Guanine deaminase	0	1	0	1
Chain A, Putative fructose-1,6-bisphosphate aldolase	2	0	0	2
Luciferase	5	0	0	5
Smad3	2	0	0	2
apical membrane antigen 1, AMA1	3	0	0	3
vitamin D3 receptor isoform VDRA	6	0	0	6
peptidyl-prolyl cis-trans isomerase NIMA-interacting 1	3	0	0	3
Solute carrier family 15 member 1	0	2	0	2
Solute carrier family 22 member 6	0	3	0	3
Solute carrier family 22 member 8	0	3	0	3
Solute carrier family 22 member 11	0	2	0	2
Solute carrier family 22 member 8	0	2	0	2
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	1	0	1
Beta-lactamase	0	0	0	1
Metallo-beta-lactamase type 2	0	0	0	1
Metallo-beta-lactamase VIM-11	0	0	0	1
Beta-lactamase	0	0	0	1
Metallo-beta-lactamase VIM-2	0	0	0	1
Beta-lactamase	0	0	0	1
Metallo-beta-lactamase VIM-19	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Metallo-beta-lactamase	0	0	0	1
Beta-lactamase	0	1	0	1
Albumin	0	1	3	4
Beta-lactamase SHV-1	0	0	0	1
Beta-lactamase SHV-1	0	0	0	1
Beta-lactamase	0	0	0	1
Kappa-type opioid receptor	0	2	0	3
B2 metallo-beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Solute carrier family 15 member 2	0	1	0	1
Metallo-beta-lactamase VIM-13	0	1	0	2
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Metallo-beta-lactamase VIM-2	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase Toho-1	0	0	0	1
Beta-lactamase	0	0	0	1
Solute carrier family 22 member 7	0	1	0	2
Metallo-beta-lactamase	0	0	0	1
Solute carrier family 15 member 2	0	1	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Metallo-b-lactamase	0	0	0	1
BlaVIM-1	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Carbapenem-hydrolyzing beta-lactamase KPC	0	0	0	1
Histamine H3 receptor	0	0	0	1
Beta-lactamase class B VIM-2	0	0	0	1
Beta-lactamase VIM-1	0	1	0	2
Solute carrier family 22 member 7	0	1	0	1
PPM1D protein	3	0	0	3
glucose-6-phosphate dehydrogenase-6-phosphogluconolactonase	0	1	0	1
Spike glycoprotein	0	1	2	3
Replicase polyprotein 1ab	0	1	2	3
glucose-6-phosphate 1-dehydrogenase isoform b	0	1	0	1
Transmembrane protease serine 2	0	1	2	3
Dihydrofolate reductase	0	2	0	2
DNA ligase	0	1	0	1
Interferon beta	9	0	0	9
Riboflavin-binding protein	0	0	1	1
Major prion protein	0	0	1	1
Amyloid-beta precursor protein	0	4	0	4
Histidine-rich protein PFHRP-II	0	1	0	2
Procathepsin L	0	1	2	3
Muscarinic acetylcholine receptor M2	0	7	1	8
Muscarinic acetylcholine receptor M4	0	7	1	8
Cytochrome P450 3A4	0	7	1	9
Muscarinic acetylcholine receptor M5	0	7	0	7
Alpha-2A adrenergic receptor	0	7	1	8
Replicase polyprotein 1a	0	1	2	3
Replicase polyprotein 1ab	0	1	2	3
Spike glycoprotein	0	1	0	1
Muscarinic acetylcholine receptor M1	0	7	1	8
Ribosyldihydronicotinamide dehydrogenase [quinone]	0	1	0	1
Alpha-2B adrenergic receptor	0	7	0	7
Alpha-2C adrenergic receptor	0	5	0	5
DNA ligase 1	0	1	0	1
Muscarinic acetylcholine receptor M3	0	7	1	8
Nuclear receptor subfamily 4 group A member 2	0	0	2	2
Beta-secretase 1	0	1	0	1
Calcium-dependent protein kinase 1	0	0	1	1
MO15-related protein kinase Pfmrk	0	1	0	1
DNA ligase A	0	1	0	1
Potassium voltage-gated channel subfamily H member 2	0	12	0	12
Sigma intracellular receptor 2	0	1	0	1
Phosphoethanolamine N-methyltransferase	0	1	0	1
Angiotensin-converting enzyme 2	0	1	2	3
Cysteine proteinase falcipain 2a	0	1	0	1
Cysteine proteinase falcipain 2a	0	1	0	1
NPC intracellular cholesterol transporter 1 precursor	3	0	0	3
Solute carrier family 22 member 1	0	3	0	3
Sodium-dependent noradrenaline transporter	0	1	0	1
5-hydroxytryptamine receptor 4	0	8	0	8
Aldo-keto reductase family 1 member B1	0	8	0	8
Tryptophan 5-hydroxylase 1	0	1	0	1
Angiotensin-converting enzyme	0	6	0	6
Aldo-keto reductase family 1 member B1	0	2	0	2
Aromatase	0	1	0	1
Sodium-dependent noradrenaline transporter	0	8	0	8
Sodium-dependent dopamine transporter	0	3	1	4
Alpha-1D adrenergic receptor	0	8	0	8
5-hydroxytryptamine receptor 2C	0	8	1	9
Histamine H1 receptor	0	6	2	10
5-hydroxytryptamine receptor 2B	0	8	1	9
5-hydroxytryptamine receptor 7	0	2	0	2
Sodium-dependent dopamine transporter	0	6	0	6
Sigma intracellular receptor 2	0	1	0	1
Sodium-dependent serotonin transporter	0	1	0	1
Sodium-dependent dopamine transporter	0	1	0	1
Nuclear receptor subfamily 3 group C member 3	0	6	0	6
Transporter	0	3	0	3
Protein-arginine deiminase type-4	0	3	0	3
5-hydroxytryptamine receptor 3E	0	1	0	1
hypoxia-inducible factor 1 alpha subunit	7	0	0	7
Fumarate hydratase	2	0	0	2
caspase 7, apoptosis-related cysteine protease	2	0	0	2
estrogen receptor 2 (ER beta)	9	0	0	9
progesterone receptor	8	0	0	8
G	7	0	0	7
polyprotein	2	0	0	2
Beta-1 adrenergic receptor	0	1	0	1
bromodomain adjacent to zinc finger domain 2B	4	0	0	4
caspase-3	2	0	0	2
Adenylate cyclase type 1	0	1	0	1
Histone H2A.x	6	0	0	6
cytochrome P450 2D6 isoform 1	4	0	0	4
peripheral myelin protein 22 isoform 1	2	0	0	2
cytochrome P450 2C19 precursor	2	0	0	2
cytochrome P450 2C9 precursor	2	0	0	2
potassium voltage-gated channel subfamily H member 2 isoform d	2	0	0	2
mitogen-activated protein kinase 1	2	0	0	2
atrial natriuretic peptide receptor 2 precursor	2	0	0	2
short transient receptor potential channel 6 isoform 1	0	0	1	1
cytochrome P450 3A4 isoform 1	4	0	0	4
M-phase phosphoprotein 8	3	0	0	3
transient receptor potential cation channel subfamily V member 1	1	0	0	1
Gamma-aminobutyric acid receptor subunit pi	4	6	0	10
Polyunsaturated fatty acid lipoxygenase ALOX15B	5	0	0	5
Voltage-dependent L-type calcium channel subunit alpha-1F	0	3	0	3
Bile salt export pump	0	2	0	2
5-hydroxytryptamine receptor 3A	0	1	0	1
5-hydroxytryptamine receptor 3B	0	1	0	1
HLA class I histocompatibility antigen, B alpha chain	7	0	0	7
Albumin	0	0	1	1
ATP-dependent translocase ABCB1	0	5	1	7
Muscarinic acetylcholine receptor M1	0	3	0	3
Muscarinic acetylcholine receptor M3	0	3	0	3
Muscarinic acetylcholine receptor M4	0	3	0	3
5-hydroxytryptamine receptor 1A	0	3	0	3
Muscarinic acetylcholine receptor M5	0	3	0	3
Calmodulin-1	0	1	0	1
Beta-2 adrenergic receptor	0	2	0	2
Cytochrome P450 2D6	0	3	0	5
Muscarinic acetylcholine receptor M2	0	4	0	4
Cytochrome P450 2C9	0	5	0	6
D(2) dopamine receptor	0	4	0	7
Gamma-aminobutyric acid receptor subunit beta-1	4	6	0	10
Alpha-1B adrenergic receptor	0	4	1	5
Beta-1 adrenergic receptor	0	2	0	2
Gamma-aminobutyric acid receptor subunit delta	4	6	0	10
Gamma-aminobutyric acid receptor subunit gamma-2	4	6	1	11
D	0	2	0	2
D(3) dopamine receptor	0	2	0	2
Alpha-2B adrenergic receptor	0	2	1	3
Gamma-aminobutyric acid receptor subunit alpha-5	4	6	0	10
Gamma-aminobutyric acid receptor subunit alpha-3	4	6	0	10
D(2) dopamine receptor	0	2	0	2
Endothelin receptor type B	0	1	0	1
D(1A) dopamine receptor	0	6	0	7
D(4) dopamine receptor	0	4	0	6
D(1B) dopamine receptor	0	1	0	2
Adenylate cyclase type 3	0	1	0	1
Alpha-2C adrenergic receptor	0	2	1	3
UDP-glucuronosyltransferase 1A4	0	0	0	2
Alpha-2A adrenergic receptor	0	2	1	3
Gamma-aminobutyric acid receptor subunit gamma-1	4	6	0	10
Gamma-aminobutyric acid receptor subunit alpha-2	4	6	0	10
Alpha-1D adrenergic receptor	0	2	1	3
5-hydroxytryptamine receptor 3A	0	1	0	1
Endothelin receptor type B	0	1	0	1
Histamine H2 receptor	0	6	0	6
D(1B) dopamine receptor	0	2	0	2
Beta-3 adrenergic receptor	0	1	0	1
Adenylate cyclase type 2	0	1	1	2
Adenylate cyclase type 4	0	1	0	1
5-hydroxytryptamine receptor 2A	0	6	0	8
Gamma-aminobutyric acid receptor subunit alpha-4	4	6	0	10
Gamma-aminobutyric acid receptor subunit gamma-3	4	6	0	10
Gamma-aminobutyric acid receptor subunit alpha-6	4	6	0	10
D(4) dopamine receptor	0	2	0	2
Histamine H1 receptor	0	1	0	1
Histamine H1 receptor	0	3	0	3
Cytochrome P450 2C19	0	2	0	3
5-hydroxytryptamine receptor 2C	0	1	0	1
5-hydroxytryptamine receptor 7	0	1	0	1
Alpha-1A adrenergic receptor	0	1	0	1
5-hydroxytryptamine receptor 2A	0	1	0	1
Alpha-1B adrenergic receptor	0	1	0	1
D(3) dopamine receptor	0	6	0	8
Adenylate cyclase type 8	0	1	0	1
Alpha-1A adrenergic receptor	0	5	1	6
5-hydroxytryptamine receptor 3A	0	1	0	1
Histamine H2 receptor	6	1	0	8
5-hydroxytryptamine receptor 5A	0	1	0	1
5-hydroxytryptamine receptor 6	0	6	0	7
Cytochrome P450 2J2	0	3	0	4
3-hydroxy-3-methylglutaryl-coenzyme A reductase	0	2	0	2
D(2) dopamine receptor	0	1	0	1
D(3) dopamine receptor	0	1	0	1
Gastrin/cholecystokinin type B receptor	0	1	0	1
D(2) dopamine receptor	0	1	0	1
D(2) dopamine receptor	0	2	0	2
Calmodulin	0	0	1	1
Gamma-aminobutyric acid receptor subunit beta-3	4	6	0	10
Gamma-aminobutyric acid receptor subunit beta-2	4	6	1	11
Inositol monophosphatase 1	3	0	0	3
Voltage-dependent L-type calcium channel subunit alpha-1D	0	3	0	3
5-hydroxytryptamine receptor 2B	0	1	0	1
Adenylate cyclase type 6	0	1	0	1
Adenylate cyclase type 5	0	1	0	1
5-hydroxytryptamine receptor 4	0	1	0	1
Voltage-dependent L-type calcium channel subunit alpha-1S	0	3	0	3
Voltage-dependent L-type calcium channel subunit alpha-1C	0	3	0	3
Transporter	0	1	0	1
Cholecystokinin receptor type A	0	1	0	1
5-hydroxytryptamine receptor 1A	0	1	0	1
5-hydroxytryptamine receptor 3D	0	1	0	1
Adenylyl cyclase 7	0	1	0	1
5-hydroxytryptamine receptor 3C	0	1	0	1
GABA theta subunit	4	6	0	10
Inositol hexakisphosphate kinase 1	7	0	0	7
D	0	2	0	2
Gamma-aminobutyric acid receptor subunit epsilon	4	6	0	10
Histamine H4 receptor	0	1	1	2
Histamine H3 receptor	0	1	0	1
cytochrome P450 2C9, partial	7	0	0	7
glp-1 receptor, partial	4	0	0	4
peroxisome proliferator activated receptor gamma	10	0	0	10
aryl hydrocarbon receptor	6	0	0	6
nuclear receptor subfamily 1, group I, member 2	2	0	0	2
nuclear receptor subfamily 0 group B member 1	0	1	0	1
steroidogenic factor 1	0	1	0	1
histone-lysine N-methyltransferase 2A isoform 2 precursor	2	0	0	2
relaxin receptor 1 isoform 1	1	0	0	1
relaxin receptor 2 isoform 1	1	0	0	1
Nuclear receptor subfamily 1 group I member 2	0	0	3	3
Rap guanine nucleotide exchange factor 3	2	0	0	2
Cellular tumor antigen p53	15	0	0	15
Solute carrier family 2, facilitated glucose transporter member 1	0	0	1	1
Adenylate cyclase type 8	0	0	1	1
Relaxin receptor 1	0	0	1	1
Nuclear receptor subfamily 1 group I member 2	0	0	1	1
activating transcription factor 6	4	0	0	4
B2 bradykinin receptor	0	1	0	1
Dihydrofolate reductase	0	0	0	1
Dihydrofolate reductase	0	1	0	1
Chymotrypsinogen A	0	0	0	1
Beta-lactamase	0	1	0	1
Beta-lactamase	0	0	0	1
Beta-galactosidase	0	1	0	2
Choline O-acetyltransferase	0	1	0	1
Ectonucleotide pyrophosphatase/phosphodiesterase family member 2	0	2	0	2
PH domain leucine-rich repeat-containing protein phosphatase 2	0	1	0	1
Chymotrypsin-C	0	1	0	1
Vasopressin V2 receptor	0	1	1	2
Oxytocin receptor	0	0	1	1
Vasopressin V1a receptor	0	1	1	2
Vasopressin V1b receptor	0	1	1	2
Translocator protein	0	1	0	1
Vasopressin V2 receptor	0	1	1	2
Glutamate receptor ionotropic, NMDA 2D	0	2	0	2
Glutamate receptor ionotropic, NMDA 3B	0	2	0	2
Neuronal acetylcholine receptor subunit alpha-3	0	1	0	1
Sodium channel protein type 1 subunit alpha	0	1	0	1
Sodium channel protein type 2 subunit alpha	0	2	0	2
Sodium channel protein type 3 subunit alpha	0	1	0	1
Cytochrome P450 2D1	0	2	0	2
Cytochrome P450 2D26	0	2	0	2
Neuronal acetylcholine receptor subunit beta-4	0	1	0	1
Cytochrome P450 2D3	0	2	0	2
Glutamate receptor ionotropic, NMDA 1	0	3	1	4
Taste receptor type 2 member 46	0	0	1	1
Glutamate receptor ionotropic, NMDA 2A	0	3	1	4
Glutamate receptor ionotropic, NMDA 2B	0	3	1	4
Glutamate receptor ionotropic, NMDA 2C	0	3	1	4
Glutamate receptor ionotropic, NMDA 1	0	2	0	2
Glutamate receptor ionotropic, NMDA 2A	0	2	0	2
Glutamate receptor ionotropic, NMDA 2B	0	2	0	2
Glutamate receptor ionotropic, NMDA 2C	0	2	0	2
Sigma non-opioid intracellular receptor 1	0	3	0	3
Glutamate receptor ionotropic, NMDA 2D	0	3	1	4
Cytochrome P450 2D4	0	2	0	2
Glutamate receptor ionotropic, NMDA 3A	0	2	0	2
Glutamate receptor ionotropic, NMDA 3B	0	3	1	4
Glutamate receptor ionotropic, NMDA 3A	0	3	1	4
Eyes absent homolog 2	0	1	0	1
Angiotensin-converting enzyme	0	1	0	1
Beta-lactamase	0	1	0	1
Beta-lactamase	0	1	0	1
Voltage-dependent T-type calcium channel subunit alpha-1I	0	1	0	1
cellular tumor antigen p53 isoform a	5	0	0	5
Endolysin	0	0	2	2
Steroid 17-alpha-hydroxylase/17,20 lyase	0	1	0	1
Aromatase	0	2	0	2
Cytochrome P450 11B1, mitochondrial	0	1	0	1
Cytochrome P450 11B2, mitochondrial	0	1	0	1
Cytochrome P450 11B2, mitochondrial	0	1	0	1
Cytochrome P450 11B2, mitochondrial	0	1	0	1
nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105), isoform CRA_a	4	0	0	4
thioredoxin glutathione reductase	1	0	0	1
ubiquitin carboxyl-terminal hydrolase 2 isoform a	1	0	0	1
Voltage-dependent calcium channel subunit alpha-2/delta-1	0	1	0	1
Chain A, Ferritin light chain	5	0	0	5
Gamma-aminobutyric acid	0	1	1	2
Gamma-aminobutyric acid receptor subunit rho-3	0	0	1	1
Hsf1 protein	0	0	2	3
transcriptional regulator ERG isoform 3	3	0	0	3
histone acetyltransferase KAT2A isoform 1	3	0	0	3
Gamma-aminobutyric acid receptor subunit pi	0	2	0	2
Gamma-aminobutyric acid receptor subunit delta	0	2	0	2
Gamma-aminobutyric acid type B receptor subunit 2	0	0	1	1
Gamma-aminobutyric acid type B receptor subunit 2	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-1	0	3	2	5
Gamma-aminobutyric acid receptor subunit alpha-6	0	1	1	2
Gamma-aminobutyric acid receptor subunit beta-1	0	3	1	4
Gamma-aminobutyric acid receptor subunit gamma-2	0	3	2	5
Gamma-aminobutyric acid receptor subunit gamma-2	0	1	1	2
Gamma-aminobutyric acid receptor subunit delta	0	1	1	2
Sodium- and chloride-dependent GABA transporter 1	0	1	0	1
Gamma-aminobutyric acid receptor subunit rho-1	0	0	2	2
Gamma-aminobutyric acid receptor subunit alpha-2	0	1	1	2
Gamma-aminobutyric acid receptor subunit alpha-3	0	1	1	2
Gamma-aminobutyric acid receptor subunit gamma-3	0	1	1	2
Gamma-aminobutyric acid receptor subunit beta-3	0	3	1	4
Gamma-aminobutyric acid receptor subunit rho-2	0	0	1	1
Sodium- and chloride-dependent GABA transporter 1	0	1	0	1
Sodium- and chloride-dependent taurine transporter	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-5	0	3	2	5
Sodium- and chloride-dependent GABA transporter 2	0	1	0	1
Sodium- and chloride-dependent GABA transporter 3	0	1	0	1
Sodium- and chloride-dependent GABA transporter 1	0	2	0	2
Sodium- and chloride-dependent GABA transporter 2	0	2	0	2
Sodium- and chloride-dependent GABA transporter 3	0	2	0	2
Gamma-aminobutyric acid receptor subunit alpha-3	0	3	2	5
Gamma-aminobutyric acid receptor subunit alpha-2	0	3	2	5
Gamma-aminobutyric acid receptor subunit beta-2	0	3	2	5
Sodium- and chloride-dependent betaine transporter	0	1	0	1
Sodium- and chloride-dependent betaine transporter	0	1	0	1
Sodium- and chloride-dependent GABA transporter 3	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-4	0	3	1	4
Gamma-aminobutyric acid receptor subunit beta-1	0	1	1	2
Gamma-aminobutyric acid receptor subunit alpha-1	0	1	1	2
Gamma-aminobutyric acid receptor subunit beta-3	0	1	1	2
Gamma-aminobutyric acid receptor subunit epsilon	0	2	0	2
4-aminobutyrate aminotransferase, mitochondrial	0	0	0	1
4-aminobutyrate aminotransferase, mitochondrial	0	0	0	1
TAR DNA-binding protein 43	4	0	0	4
Gamma-aminobutyric acid receptor subunit alpha-6	0	3	1	4
Sterol O-acyltransferase 1	0	0	1	1
Proton-coupled amino acid transporter 1	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-5	0	1	1	2
Gamma-aminobutyric acid receptor subunit gamma-1	0	2	0	2
Gamma-aminobutyric acid receptor subunit pi	0	1	1	2
Gamma-aminobutyric acid receptor subunit gamma-3	0	2	0	2
Gamma-aminobutyric acid receptor subunit alpha-4	0	1	1	2
Platelet glycoprotein VI	0	0	1	1
Gamma-aminobutyric acid receptor subunit theta	0	1	1	2
Sodium- and chloride-dependent GABA transporter 2	0	1	0	1
Gamma-aminobutyric acid receptor subunit gamma-1	0	1	1	2
Gamma-aminobutyric acid type B receptor subunit 1	0	0	1	1
Gamma-aminobutyric acid receptor subunit theta	0	2	0	2
Gamma-aminobutyric acid type B receptor subunit 1	0	1	0	1
Chain A, GLUTAMATE RECEPTOR SUBUNIT 2	0	1	0	1
Chain A, Glutamate Receptor Subunit 2	0	1	0	1
Chain B, Glutamate Receptor Subunit 2	0	1	0	1
Chain A, Slr1257 protein	0	0	1	1
Chain A, Glucosamine--fructose-6-phosphate aminotransferase [isomerizing]	0	1	0	1
beta-2 adrenergic receptor	2	0	0	2
Metabotropic glutamate receptor 8	0	2	0	2
Metabotropic glutamate receptor 6	0	1	1	3
Excitatory amino acid transporter 4	0	1	0	1
Glutathione reductase, mitochondrial	0	2	0	2
Bifunctional aspartokinase/homoserine dehydrogenase 1	0	1	0	1
Prothrombin	0	0	1	1
ATP-citrate synthase	0	1	0	1
Glutamate receptor 1	0	2	1	3
Glutamate receptor 3	0	2	1	3
Glutamate receptor 4	0	2	1	3
Glutamate receptor ionotropic, kainate 1	0	2	1	3
Metabotropic glutamate receptor 1	0	1	1	2
Metabotropic glutamate receptor 2	0	0	1	1
Metabotropic glutamate receptor 3	0	0	1	1
Metabotropic glutamate receptor 4	0	1	1	2
Metabotropic glutamate receptor 5	0	0	1	1
Metabotropic glutamate receptor 6	0	0	1	1
Metabotropic glutamate receptor 7	0	0	1	1
Glutamate receptor ionotropic, kainate 1	0	1	1	2
Metabotropic glutamate receptor 5	0	1	1	3
Glutamate receptor ionotropic, kainate 2	0	2	1	3
Glutamate receptor 1	0	2	1	3
Glutamate receptor 2	0	2	1	3
Glutamate receptor 3	0	1	1	2
Glutamate receptor ionotropic, kainate 3	0	2	0	2
Excitatory amino acid transporter 1	0	2	0	3
Excitatory amino acid transporter 2	0	2	0	3
Excitatory amino acid transporter 3	0	2	0	3
Metabotropic glutamate receptor 8	0	0	1	1
Glutamate receptor 4	0	2	1	3
Excitatory amino acid transporter 3	0	0	0	1
Glutamate racemase	0	0	0	1
Metabotropic glutamate receptor 8	0	1	1	2
Fatty-acid amide hydrolase 1	0	1	0	1
Glutamate receptor ionotropic, kainate 4	0	2	0	2
Glutamate carboxypeptidase 2	0	1	0	1
Glutamate receptor ionotropic, kainate 2	0	1	1	2
Glutamate receptor ionotropic, kainate 3	0	1	0	1
Metabotropic glutamate receptor 1	0	1	1	3
Metabotropic glutamate receptor 2	0	1	1	3
Metabotropic glutamate receptor 7	0	1	1	3
Metabotropic glutamate receptor 3	0	1	1	3
Metabotropic glutamate receptor 4	0	1	1	3
Glutamate receptor ionotropic, kainate 5	0	1	0	1
Carbonic anhydrase-like protein, putative	0	0	0	1
Glutamate receptor ionotropic, kainate 5	0	2	0	2
Glutamate racemase	0	0	0	1
Prolyl 4-hydroxylase	0	2	0	2
Alpha-ketoglutarate-dependent dioxygenase FTO	0	2	0	2
Chain B, EUKARYOTIC TRANSLATION INITIATION FACTOR 4E	0	0	1	1
Carbonic anhydrase	0	1	0	1
Carbonic anhydrase	0	1	0	1
Carbonic anhydrase 4	0	2	0	2
Carbonic anhydrase 6	0	2	0	2
Carbonic anhydrase 5A, mitochondrial	0	2	0	2
Carbonic anhydrase	0	1	0	1
Carbonic anhydrase 7	0	2	0	2
Carbonic anhydrase 9	0	2	0	2
Carbonic anhydrase, alpha family	0	1	0	1
Carbonic anhydrase	0	1	0	1
Carbonic anhydrase 13	0	2	0	2
Carbonic anhydrase 5B, mitochondrial	0	2	0	2
Neuronal acetylcholine receptor subunit beta-2	0	1	0	1
Neuronal acetylcholine receptor subunit alpha-7	0	1	0	1
chaperonin-containing TCP-1 beta subunit homolog	2	0	0	2
Synaptic vesicle glycoprotein 2A	0	2	0	2
Thioredoxin reductase	0	1	0	1
muscleblind-like protein 1 isoform 1	1	0	0	1
Flavodoxin	0	0	0	1
Lanosterol 14-alpha demethylase	0	1	0	1
Stromelysin-1	0	1	1	2
Matrilysin	0	1	0	1
Multidrug transporter MdfA	0	1	0	1
Matrix metalloproteinase-9	0	1	0	1
Protein mono-ADP-ribosyltransferase PARP15	0	1	0	1
Nuclear receptor corepressor 1	0	1	0	1
Integrin beta-1	0	1	0	1
Leukotriene A-4 hydrolase	0	1	0	1
Integrin alpha-4	0	1	0	1
Nuclear receptor corepressor 2	0	1	0	1
Opioid receptor, delta 1b	0	1	0	1
Acetylcholinesterase	0	1	0	1
Opioid receptor homologue	0	1	0	1
ATP-dependent translocase ABCB1	0	1	0	1
Acyl-CoA desaturase 1	0	1	0	1
Translocator protein	0	1	1	2
Histidine decarboxylase	0	0	1	1
ATP-dependent translocase ABCB1	0	1	0	1
Proteinase-activated receptor 1	0	1	1	2
Delta-type opioid receptor	0	1	0	2
Delta-type opioid receptor	0	2	1	4
Kappa-type opioid receptor	0	2	1	4
Mu-type opioid receptor	0	2	1	6
Kappa-type opioid receptor	0	2	1	4
Mu-type opioid receptor	0	4	1	6
UDP-glucuronosyltransferase 1A3	0	0	0	1
Delta-type opioid receptor	0	4	1	6
Kappa-type opioid receptor	0	4	1	6
Mu-type opioid receptor	0	2	1	5
Nociceptin receptor	0	1	0	1
Mu-type opioid receptor	0	1	0	1
Mu-type opioid receptor	0	2	0	2
Beta-2 adrenergic receptor	0	1	0	1
Mas-related G-protein coupled receptor member X2	0	0	1	1
Mu-type opioid receptor	0	1	0	1
67.9K protein	3	0	0	3
heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)	3	0	0	3
huntingtin isoform 2	1	0	0	1
ras-related protein Rab-9A	2	0	0	2
serine/threonine-protein kinase mTOR isoform 1	2	0	0	2
Cytochrome P450 2C8	0	1	0	1
Sodium- and chloride-dependent betaine transporter	0	1	0	1
D(1A) dopamine receptor	2	0	0	2
Voltage-dependent N-type calcium channel subunit alpha-1B	0	1	0	1
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	1	0	1
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	1	0	1
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	1	0	1
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	1	0	1
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	1	0	1
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	1	0	1
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	1	0	1
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	1	0	1
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	1	0	1
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	1	0	1
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	1	0	1
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	1	0	1
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	1	0	1
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	1	0	1
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	1	0	1
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	1	0	1
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	1	0	1
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	1	0	1
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	1	0	1
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	1	0	1
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	1	0	1
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	1	0	1
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	1	0	1
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	1	0	1
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	1	0	1
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	1	0	1
Chain A, Pyruvate kinase, M2 isozyme	0	1	0	1
Chain A, Phosphonopyruvate hydrolase	0	1	0	1
Chain A, Phosphoenolpyruvate-protein phosphotransferase	0	1	0	1
Proto-oncogene tyrosine-protein kinase Src	0	1	0	1
Tyrosine-protein phosphatase non-receptor type 1	0	2	0	4
Sodium channel protein type 1 subunit alpha	0	2	0	2
Sodium channel protein type 2 subunit alpha	0	2	0	2
Sodium channel protein type 3 subunit alpha	0	2	0	2
GALC protein	1	0	0	1
hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)	1	0	0	1
lysosomal alpha-glucosidase preproprotein	1	0	0	1
mu-type opioid receptor isoform MOR-1	0	0	1	1
Vpr	1	0	0	1
5-hydroxytryptamine receptor 2A	0	0	1	1
Neuronal acetylcholine receptor subunit alpha-4	1	0	0	1
Neuronal acetylcholine receptor subunit beta-2	1	0	0	1
endonuclease IV	1	0	0	1
parathyroid hormone/parathyroid hormone-related peptide receptor precursor	1	0	0	1
Voltage-dependent L-type calcium channel subunit alpha-1C	0	1	0	1
Sodium channel protein type 4 subunit alpha	0	1	0	2
Sodium channel protein type 5 subunit alpha	0	1	0	1
Sodium channel protein type 9 subunit alpha	0	1	0	1
Chain A, Beta-lactamase	4	0	0	4
SMAD family member 2	3	0	0	3
SMAD family member 3	3	0	0	3
nonstructural protein 1	1	0	0	1
heat shock protein HSP 90-alpha isoform 2	0	0	0	1
heat shock protein 90, putative	0	0	0	1
Monocarboxylate transporter 4	0	0	0	1
Monocarboxylate transporter 2	0	0	0	1
Monocarboxylate transporter 1	0	0	0	1
C-terminal-binding protein 2	0	1	0	1
Monocarboxylate transporter 2	0	1	0	1
Solute carrier organic anion transporter family member 2A1	0	1	0	1
Estrogen receptor beta	0	0	0	1
Inhibitor of nuclear factor kappa-B kinase subunit beta	0	0	0	1
Polyphenol oxidase 2	0	1	0	2
Carbonic anhydrase 12	0	1	0	1
5'-AMP-activated protein kinase subunit beta-2	0	0	0	1
Polymerase acidic protein	0	0	1	1
Carbonic anhydrase 3	0	1	0	1
Tyrosine-protein phosphatase YopH	0	1	0	1
High mobility group protein B1	0	0	1	1
Aldo-keto reductase family 1 member B1	0	1	0	1
Prolyl 4-hydroxylase subunit alpha-1	0	1	0	1
Estrogen receptor	0	0	0	1
Cystathionine gamma-lyase	0	1	0	1
5'-AMP-activated protein kinase subunit gamma-1	0	0	0	1
5'-AMP-activated protein kinase catalytic subunit alpha-2	0	0	0	1
Xanthine dehydrogenase/oxidase	0	1	0	1
5'-AMP-activated protein kinase catalytic subunit alpha-1	0	0	0	1
Carbonic anhydrase	0	1	0	1
Ubiquitin-like domain-containing CTD phosphatase 1	0	1	0	1
Carbonic anhydrase 15	0	1	0	1
5'-AMP-activated protein kinase subunit gamma-3	0	0	0	1
5'-AMP-activated protein kinase subunit gamma-2	0	0	0	1
Carbonic anhydrase 14	0	1	0	1
5'-AMP-activated protein kinase subunit beta-1	0	0	0	1
PINK1	1	0	0	1
Parkin	1	0	0	1
photoreceptor-specific nuclear receptor	0	1	0	1
nuclear factor erythroid 2-related factor 2 isoform 2	1	0	0	1
serine/threonine-protein kinase PLK1	2	0	0	2
urokinase-type plasminogen activator precursor	1	0	0	1
plasminogen precursor	1	0	0	1
urokinase plasminogen activator surface receptor precursor	1	0	0	1
transactivating tegument protein VP16 [Human herpesvirus 1]	0	1	0	1
DNA dC->dU-editing enzyme APOBEC-3G isoform 1	1	0	0	1
3-hydroxy-3-methylglutaryl-coenzyme A reductase	0	2	0	2
Insulin receptor	0	1	0	1
3-hydroxy-3-methylglutaryl-coenzyme A reductase	0	1	0	1
Solute carrier organic anion transporter family member 1B1	0	1	0	2
Chain A, Acetylcholinesterase	0	0	1	1
Chain A, Acetylcholinesterase	0	0	1	1
Chain A, Acetylcholinesterase	0	0	1	1
Chain A, Acetylcholinesterase	0	0	1	1
Chain A, Acetylcholinesterase	0	0	1	1
Chain A, Acetylcholinesterase	0	0	1	1
Chain A, Acetylcholinesterase	0	0	1	1
Acetylcholinesterase	0	1	0	1
Chain A, CES1 protein	0	1	0	1
DNA polymerase III, partial	1	0	0	1
thyrotropin-releasing hormone receptor	1	0	0	1
Caspase-7	1	0	0	1
interferon gamma precursor	0	0	0	1
caspase-3	1	0	0	1
ubiquitin-conjugating enzyme E2 N	0	1	0	1
streptokinase A precursor	0	0	1	1
Serine/threonine-protein kinase D3	0	1	1	2
Estrogen receptor	0	2	1	4
Lysosomal acid glucosylceramidase	0	0	1	1
Receptor tyrosine-protein kinase erbB-2	0	1	0	1
Protein kinase C gamma type	0	2	1	3
Protein kinase C alpha type	0	1	0	1
Protein kinase C beta type	0	2	1	3
Estrogen receptor	0	0	1	2
Tyrosine-protein kinase Lck	0	1	0	1
Tyrosine-protein kinase Fyn	0	1	0	1
Progesterone receptor	0	1	0	1
Beta-1 adrenergic receptor	0	2	0	2
Protein kinase C delta type	0	1	0	1
Protein kinase C epsilon type	0	1	0	1
Protein kinase C zeta type	0	1	0	1
Polyunsaturated fatty acid 5-lipoxygenase	0	1	0	1
Steroid hormone receptor ERR1	0	1	0	1
Transcriptional activator protein LuxR	0	1	0	1
Beta-3 adrenergic receptor	0	2	0	2
Androgen receptor	0	2	0	2
Protein kinase C alpha type	0	2	1	3
Cytochrome P450 2B6	0	1	0	1
Substance-K receptor	0	2	0	2
Thromboxane-A synthase	0	1	0	1
Protein kinase C eta type	0	1	1	2
Substance-P receptor	0	2	0	2
B2 bradykinin receptor	0	2	0	2
Melanocortin receptor 4	0	2	0	2
C-8 sterol isomerase	0	1	0	1
Melanocortin receptor 5	0	2	0	2
Alpha-synuclein	1	0	0	1
Protein kinase C iota type	0	1	1	2
Melanocortin receptor 3	0	2	0	2
Estrogen-related receptor gamma	0	1	0	1
Protein kinase C gamma type	0	1	0	1
Protein kinase C beta type	0	1	0	1
Phospholipase D1	0	1	0	1
Protein kinase C epsilon type	0	2	1	3
Protein kinase C theta type	0	1	1	2
Protein kinase C zeta type	0	1	1	2
Protein kinase C delta type	0	2	1	3
Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform	0	1	0	1
Platelet-activating factor acetylhydrolase	0	1	0	1
Phospholipase D1	0	1	0	1
3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase	0	2	1	3
Serine/threonine-protein kinase D1	0	1	1	2
Estrogen receptor beta	0	0	1	2
Protein kinase C eta type	0	1	0	1
Estrogen receptor beta	0	2	1	3
Emopamil-binding protein-like	0	1	0	1
7-dehydrocholesterol reductase	0	1	1	2
Protein kinase C theta type	0	1	0	1
Luciferin 4-monooxygenase	0	0	1	1
Ras guanyl-releasing protein 3	0	0	1	1
Chain X, Thyroid hormone receptor beta-1	0	0	1	1
Chain X, Thyroid hormone receptor beta-1	0	0	1	1
DNA polymerase eta isoform 1	1	0	0	1
Solute carrier organic anion transporter family member 1A4	0	0	0	1
Solute carrier organic anion transporter family member 1A5	0	0	0	1
Transthyretin	0	1	0	2
Thyroid hormone receptor alpha	0	0	1	1
Thyroid hormone receptor beta	0	0	1	1
Proliferating cell nuclear antigen	0	1	0	1
Retinoic acid receptor RXR-alpha	0	0	2	2
UDP-glucuronosyltransferase 1A1	0	1	0	1
Peroxisome proliferator-activated receptor gamma	0	0	2	2
Malate dehydrogenase, mitochondrial	0	1	0	1
Solute carrier organic anion transporter family member 1A2	0	0	0	1
Solute carrier organic anion transporter family member 1A3	0	0	0	1
Solute carrier organic anion transporter family member 4C1	0	1	0	1
Monocarboxylate transporter 8	0	0	0	1
Bile acid receptor	0	1	0	1
Solute carrier organic anion transporter family member 1C1	0	0	0	1
polyunsaturated fatty acid lipoxygenase ALOX12	1	0	0	1
Chain A, PLASMINOGEN	0	0	1	1
Chain A, PLASMINOGEN	0	0	1	1
Plasminogen	0	2	1	3
Urokinase-type plasminogen activator	0	1	0	1
acid sphingomyelinase	1	0	0	1
HLA class I histocompatibility antigen, A alpha chain	0	0	1	1
Neuronal acetylcholine receptor subunit alpha-7	0	1	0	1
Sphingosine-1-phosphate lyase 1	0	1	0	1
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]

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Brain Injuries, Penetrating

Synonyms(9)

Research Excerpts

Overview

Treatment

Research

Studies (179)

Drugs Studied (96)

Protein Targets (886)