Bovine Digital Dermatitis

Highly contagious infectious dermatitis with lesions near the interdigital spaces usually in cattle. It causes discomfort and often severe lameness (LAMENESS, ANIMAL). Lesions can be either erosive or proliferative and wart-like with papillary growths and hypertrophied hairs. DICHELOBACTER NODOSUS and TREPONEMA are the most commonly associated causative agents for this mixed bacterial infection disease.

Synonym
Ovine Digital Dermatitis
Papillomatous Digital Dermatitis
Digital Papillomatosis
Bovine Foot Warts
Bovine Hairy Footwarts
Bovine Digital Dermatitis
Digital Dermatitis

Excerpt	Reference
"Digital dermatitis is an infectious disease that causes lameness in dairy cattle, a primary welfare concern of the dairy industry."	( Cramer, G; Cutler, JH; Kelton, DF; Millman, ST; Walter, JJ, 2013)
"Digital dermatitis is a major problem in modern dairy production because of decreased animal welfare and financial losses."	( Thomsen, PT, 2015)
"Digital Dermatitis is a localized infectious dermatitis caused by Treponema-like spirochetes."	( Manabe, H; Misawa, N; Okada, K; Takahashi, M; Yamamoto, T; Yamazaki, W, 2018)

Excerpt	Reference
"This study aimed to catalogue the digital dermatitis (DD) treatment practices used by French dairy farmers and to identify the motivators and barriers to the adoption of these treatments."	( Auzanneau, MM; Bareille, N; Guatteo, R; Relun, A, 2013)

Timeframe	Studies, This Condition (%)	All Conditions %
pre-1990	0 (0.00)	23.3326
1990's	0 (0.00)	12.5806
2000's	0 (0.00)	18.1394
2010's	44 (72.13)	28.8240
2020's	17 (27.87)	9.53

Drug	Relationship Strength	Studies	Trials
salicylic acid	medium	5	4
3-hydroxybutyric acid	low	1	0
lactic acid	medium	1	1
formaldehyde	medium	7	1
glycolic acid	medium	1	1
iodine	medium	2	2
glutaral	low	1	0
lidocaine	low	1	0
ketoprofen	medium	1	1
allyl isothiocyanate	low	3	0
methylene blue	low	2	0
isoprene	low	1	0
gold	low	1	0
zinc sulfate	medium	1	1
copper sulfate	medium	12	4
chlorine	medium	1	1
thiamphenicol	medium	2	1
amoxicillin	low	2	0
trazodone hydrochloride	low	1	0
glucuronic acid	low	1	0
lincomycin	low	1	0
cholecalciferol	low	1	0
sodium hypochlorite	low	1	0
monoperoxysulfate	low	1	0
interleukin-8	low	2	0
tilmicosin	medium	1	1
tylosin	medium	1	1
tetracycline	medium	5	3
chlortetracycline	medium	2	1
oxytetracycline, anhydrous	medium	5	3
exudates	low	1	0

Protein Targets (397)

Protein	Potency Measurements	Inhibition Measurements	Activation Measurements	Drugs
Protein skinhead-1	0	1	0	1
Monocarboxylate transporter 2	0	1	0	1
Solute carrier family 22 member 20	0	2	0	2
Solute carrier family 22 member 6	0	2	0	2
acetylcholinesterase	4	0	0	4
AR protein	11	0	0	11
thyroid stimulating hormone receptor	2	0	0	2
progesterone receptor	5	0	0	5
retinoic acid nuclear receptor alpha variant 1	6	0	0	6
estrogen-related nuclear receptor alpha	6	0	0	6
farnesoid X nuclear receptor	3	0	0	3
pregnane X nuclear receptor	7	0	0	7
estrogen nuclear receptor alpha	12	0	0	12
aryl hydrocarbon receptor	5	0	0	5
cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a	6	0	0	6
nuclear factor erythroid 2-related factor 2 isoform 1	7	0	0	7
cytochrome P450 3A4 isoform 1	4	0	0	4
histone acetyltransferase KAT2A isoform 1	3	0	0	3
Gamma-aminobutyric acid receptor subunit pi	4	0	0	4
Transient receptor potential cation channel subfamily A member 1	0	0	1	2
Macrophage migration inhibitory factor	0	1	0	1
Gamma-aminobutyric acid receptor subunit beta-1	4	0	0	4
Gamma-aminobutyric acid receptor subunit delta	4	0	0	4
Gamma-aminobutyric acid receptor subunit gamma-2	4	0	0	4
Gamma-aminobutyric acid receptor subunit alpha-5	4	0	0	4
Gamma-aminobutyric acid receptor subunit alpha-3	4	0	0	4
Tyrosine-protein kinase JAK1	0	0	1	1
Gamma-aminobutyric acid receptor subunit gamma-1	4	0	0	4
Gamma-aminobutyric acid receptor subunit alpha-2	4	0	0	4
Gamma-aminobutyric acid receptor subunit alpha-4	4	0	0	4
Gamma-aminobutyric acid receptor subunit gamma-3	4	0	0	4
Non-receptor tyrosine-protein kinase TYK2	0	0	1	1
Gamma-aminobutyric acid receptor subunit alpha-6	4	0	0	4
Gamma-aminobutyric acid receptor subunit alpha-1	4	0	0	4
Gamma-aminobutyric acid receptor subunit beta-3	4	0	0	4
Gamma-aminobutyric acid receptor subunit beta-2	4	0	0	4
Transient receptor potential cation channel subfamily A member 1	0	1	1	2
Transient receptor potential cation channel subfamily A member 1	0	0	1	1
Transient receptor potential cation channel subfamily V member 1	0	0	1	1
Transient receptor potential cation channel subfamily M member 8	0	0	1	1
GABA theta subunit	4	0	0	4
Gamma-aminobutyric acid receptor subunit epsilon	4	0	0	4
Chain A, MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASE	5	0	0	5
Chain A, Beta-lactamase	4	0	0	4
Chain A, 2-oxoglutarate Oxygenase	6	0	0	6
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
apical membrane antigen 1, AMA1	2	0	0	2
Beta-lactamase	0	0	0	1
peptidyl-prolyl cis-trans isomerase NIMA-interacting 1	3	0	0	3
DNA polymerase eta isoform 1	3	0	0	3
DNA polymerase iota isoform a (long)	3	0	0	3
urokinase-type plasminogen activator precursor	2	0	0	2
plasminogen precursor	2	0	0	2
urokinase plasminogen activator surface receptor precursor	2	0	0	2
DNA polymerase kappa isoform 1	4	0	0	4
ATP-binding cassette sub-family C member 3	0	5	0	5
Multidrug resistance-associated protein 4	0	5	0	5
Bile salt export pump	0	2	0	2
Bile salt export pump	0	6	0	6
Beta-lactamase SHV-1	0	0	0	1
Beta-lactamase SHV-1	0	0	0	1
Cytochrome P450 2C9	0	2	0	2
Beta-lactamase	0	0	0	1
Kappa-type opioid receptor	0	0	0	1
Solute carrier family 15 member 1	0	1	0	1
Solute carrier family 15 member 1	0	1	0	1
Cytochrome P450 2J2	0	2	0	2
B2 metallo-beta-lactamase	0	0	0	1
Solute carrier family 15 member 2	0	1	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Solute carrier family 15 member 2	0	1	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Canalicular multispecific organic anion transporter 1	0	4	0	4
cAMP-specific 3',5'-cyclic phosphodiesterase 4A	0	1	0	1
P2Y purinoceptor 12	0	2	0	2
Protein-arginine deiminase type-4	0	3	0	3
Chain A, HADH2 protein	3	0	0	3
Chain B, HADH2 protein	3	0	0	3
Chain A, Ferritin light chain	3	0	0	3
Chain A, Cruzipain	1	0	0	1
Luciferase	4	0	0	4
interleukin 8	3	0	0	3
15-lipoxygenase, partial	1	0	0	1
USP1 protein, partial	3	0	0	3
Microtubule-associated protein tau	5	0	0	5
aldehyde dehydrogenase 1 family, member A1	7	0	0	7
glucocorticoid receptor [Homo sapiens]	5	0	0	5
retinoid X nuclear receptor alpha	6	0	0	6
peroxisome proliferator-activated receptor delta	3	0	0	3
peroxisome proliferator activated receptor gamma	6	0	0	6
vitamin D (1,25- dihydroxyvitamin D3) receptor	3	0	0	3
euchromatic histone-lysine N-methyltransferase 2	6	0	0	6
15-hydroxyprostaglandin dehydrogenase [NAD(+)] isoform 1	5	0	0	5
vitamin D3 receptor isoform VDRA	2	0	0	2
thyroid hormone receptor beta isoform a	3	0	0	3
nuclear receptor ROR-gamma isoform 1	1	0	0	1
geminin	7	0	0	7
survival motor neuron protein isoform d	4	0	0	4
Cellular tumor antigen p53	3	0	0	3
60 kDa chaperonin	0	1	0	1
60 kDa heat shock protein, mitochondrial	0	1	0	1
Vitamin D3 receptor	0	1	1	4
Glycine receptor subunit alpha-1	0	0	1	1
Vitamin D3 receptor	0	0	1	1
Nuclear receptor ROR-gamma	3	0	0	3
10 kDa heat shock protein, mitochondrial	0	1	0	1
Thiosulfate sulfurtransferase	0	1	0	1
60 kDa chaperonin	0	1	0	1
10 kDa chaperonin	0	1	0	1
Spike glycoprotein	3	0	0	3
hypoxia-inducible factor 1 alpha subunit	3	0	0	3
RAR-related orphan receptor gamma	6	0	0	6
hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)	2	0	0	2
activating transcription factor 6	4	0	0	4
v-jun sarcoma virus 17 oncogene homolog (avian)	5	0	0	5
potassium voltage-gated channel subfamily H member 2 isoform d	2	0	0	2
thyroid hormone receptor beta isoform 2	2	0	0	2
ATPase family AAA domain-containing protein 5	2	0	0	2
Ataxin-2	2	0	0	2
histone deacetylase 9 isoform 3	2	0	0	2
Voltage-dependent calcium channel gamma-2 subunit	2	0	0	2
Glutamate receptor 2	2	0	0	2
cellular tumor antigen p53 isoform a	2	0	0	2
Integrin beta-3	2	0	0	2
Integrin alpha-IIb	2	0	0	2
GTP-binding protein (rab7)	0	0	1	1
ras protein, partial	0	0	1	1
SMAD family member 2	2	0	0	2
ATAD5 protein, partial	2	0	0	2
SMAD family member 3	2	0	0	2
GLI family zinc finger 3	3	0	0	3
nuclear receptor subfamily 1, group I, member 3	3	0	0	3
regulator of G-protein signaling 4	2	0	0	2
cytochrome P450 family 3 subfamily A polypeptide 4	5	0	0	5
EWS/FLI fusion protein	3	0	0	3
G	2	0	0	2
cytochrome P450 2D6	6	0	0	6
Rac1 protein	0	0	1	1
cell division cycle 42 (GTP binding protein, 25kDa), partial	0	0	1	1
peripheral myelin protein 22 isoform 1	1	0	0	1
mitogen-activated protein kinase 1	4	0	0	4
flap endonuclease 1	4	0	0	4
lamin isoform A-delta10	2	0	0	2
Solute carrier family 22 member 6	0	2	0	2
Epidermal growth factor receptor	0	1	0	1
Carbonic anhydrase 1	0	3	0	3
Carbonic anhydrase 2	0	3	0	3
Interferon beta	2	0	0	2
HLA class I histocompatibility antigen, B alpha chain	2	0	0	2
Albumin	0	2	1	3
Prostaglandin G/H synthase 1	0	1	0	1
Seed linoleate 13S-lipoxygenase-1	0	1	0	1
Fatty acid-binding protein, intestinal	0	1	0	1
Aldo-keto reductase family 1 member B1	0	2	0	2
UDP-glucuronosyltransferase 2B7	0	0	0	1
Prostaglandin G/H synthase 1	0	2	0	2
Serum paraoxonase/arylesterase 1	0	3	0	3
Caspase-1	0	1	0	1
Prostaglandin G/H synthase 2	0	2	0	2
UDP-glucuronosyltransferase 1A3	0	0	0	1
Caspase-3	0	1	0	1
Caspase-4	0	1	0	1
Caspase-5	0	1	0	1
Caspase-9	0	1	0	1
Ras-related protein Rab-2A	0	0	1	1
Guanine nucleotide-binding protein G	2	0	0	2
Solute carrier organic anion transporter family member 1A3	0	1	0	1
Prostaglandin G/H synthase 2	0	1	0	1
Lactoylglutathione lyase	0	1	0	1
Solute carrier family 22 member 6	0	2	0	2
Solute carrier family 22 member 7	0	1	0	2
Solute carrier family 22 member 8	0	2	0	3
Inositol hexakisphosphate kinase 1	2	0	0	2
Sigma non-opioid intracellular receptor 1	0	0	1	1
Sigma non-opioid intracellular receptor 1	0	0	1	1
cytochrome P450 2C9, partial	2	0	0	2
ATP-dependent phosphofructokinase	2	0	0	2
estrogen receptor 2 (ER beta)	2	0	0	2
thyroid stimulating hormone receptor	3	0	0	3
thioredoxin reductase	4	0	0	4
GLS protein	2	0	0	2
TDP1 protein	4	0	0	4
IDH1	2	0	0	2
chromobox protein homolog 1	4	0	0	4
muscarinic acetylcholine receptor M1	1	0	0	1
Potassium channel subfamily K member 3	0	1	0	1
Potassium channel subfamily K member 2	0	1	0	1
Sodium channel protein type 1 subunit alpha	0	1	0	1
Sodium channel protein type 2 subunit alpha	0	1	0	1
Sodium channel protein type 3 subunit alpha	0	1	0	1
Potassium voltage-gated channel subfamily A member 5	0	1	0	1
Sodium channel protein type 4 subunit alpha	0	1	0	1
Potassium voltage-gated channel subfamily H member 2	0	1	0	1
Sodium channel protein type 5 subunit alpha	0	1	0	1
Sodium channel protein type 9 subunit alpha	0	1	0	1
Potassium voltage-gated channel subfamily D member 2	0	1	0	1
Potassium channel subfamily K member 18	0	1	0	1
Multidrug and toxin extrusion protein 1	0	1	0	1
Sodium channel protein type 3 subunit alpha	0	1	0	1
Chain A, TYROSYL-DNA PHOSPHODIESTERASE	2	0	0	2
Chain E, Fibrin beta chain	0	1	0	1
Chain A, Putative fructose-1,6-bisphosphate aldolase	2	0	0	2
Chain A, JmjC domain-containing histone demethylation protein 3A	2	0	0	2
Chain A, ATP-DEPENDENT DNA HELICASE Q1	2	0	0	2
T cell receptor, partial	1	0	0	1
luteinizing hormone receptor	1	0	0	1
glp-1 receptor, partial	1	0	0	1
integrase, partial	0	1	0	1
chaperonin-containing TCP-1 beta subunit homolog	2	0	0	2
lens epithelium-derived growth factor p75	0	1	0	1
phosphopantetheinyl transferase	2	0	0	2
Caspase 6, apoptosis-related cysteine peptidase	0	0	0	1
Fumarate hydratase	1	0	0	1
PPM1D protein	1	0	0	1
TSHR protein	1	0	0	1
Apoptotic peptidase activating factor 1	0	1	0	1
thioredoxin glutathione reductase	2	0	0	2
Smad3	1	0	0	1
caspase 7, apoptosis-related cysteine protease	1	0	0	1
hypothetical protein, conserved	1	0	0	1
isocitrate dehydrogenase 1, partial	1	0	0	1
polyprotein	1	0	0	1
luciferase	1	0	0	1
bromodomain adjacent to zinc finger domain 2B	2	0	0	2
caspase-3	1	0	0	1
nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105), isoform CRA_a	1	0	0	1
Histone H2A.x	3	0	0	3
serine-protein kinase ATM isoform a	1	0	0	1
Bloom syndrome protein isoform 1	1	0	0	1
neutrophil cytosol factor 1	0	1	0	1
nuclear factor erythroid 2-related factor 2 isoform 2	1	0	0	1
parathyroid hormone/parathyroid hormone-related peptide receptor precursor	1	0	0	1
caspase-9 isoform alpha precursor	0	1	0	1
heat shock protein beta-1	1	0	0	1
huntingtin isoform 2	1	0	0	1
pyruvate kinase PKM isoform a	1	0	0	1
DNA polymerase beta	2	0	0	2
caspase-3 isoform a preproprotein	0	1	0	1
protein AF-9 isoform a	0	0	0	1
histone-lysine N-methyltransferase 2A isoform 2 precursor	1	0	0	1
Vpr	1	0	0	1
muscleblind-like protein 1 isoform 1	2	0	0	2
replicative DNA helicase	0	0	0	1
recombinase A	0	0	1	1
POsterior Segregation	0	0	1	1
DNA repair protein RAD52 homolog isoform a	0	0	0	1
neuropeptide S receptor isoform A	1	0	0	1
Glutathione reductase	0	1	0	1
Glutathione reductase, mitochondrial	0	1	0	2
Glycoprotein hormones alpha chain	1	0	0	1
Albumin	0	0	0	1
Amyloid-beta precursor protein	0	1	0	1
Dihydrolipoyl dehydrogenase, mitochondrial	0	1	0	2
Microtubule-associated protein tau	0	1	1	2
Alpha-1B adrenergic receptor	0	2	0	2
Amine oxidase [flavin-containing] A	0	1	0	1
Alpha-1D adrenergic receptor	0	2	0	2
Sodium-dependent noradrenaline transporter	0	0	1	1
Cruzipain	0	1	0	1
Alpha-synuclein	1	1	0	2
Alpha-1A adrenergic receptor	0	2	0	2
Inositol monophosphatase 1	1	0	0	1
TAR DNA-binding protein 43	1	0	0	1
Thioredoxin reductase 1, cytoplasmic	0	1	0	2
Dihydrolipoyl dehydrogenase	0	1	0	2
Zinc finger protein mex-5	0	0	1	1
phosphoglycerate kinase	2	0	0	2
WRN	1	0	0	1
Valosin-containing protein	0	1	0	1
lysosomal alpha-glucosidase preproprotein	1	0	0	1
transcriptional regulator ERG isoform 3	1	0	0	1
microphthalmia-associated transcription factor isoform 9	0	1	0	1
importin subunit beta-1 isoform 1	1	0	0	1
ubiquitin carboxyl-terminal hydrolase 2 isoform a	1	0	0	1
eukaryotic translation initiation factor 4 gamma 1 isoform 4	0	1	0	1
serine/threonine-protein kinase PLK1	1	0	0	1
snurportin-1	1	0	0	1
eukaryotic translation initiation factor 4E isoform 1	0	1	0	1
DNA dC->dU-editing enzyme APOBEC-3G isoform 1	1	0	0	1
Rap guanine nucleotide exchange factor 3	1	0	0	1
Neuronal acetylcholine receptor subunit alpha-4	1	0	0	1
Neuronal acetylcholine receptor subunit beta-2	1	0	0	1
Estrogen receptor beta	0	0	0	1
Inhibitor of nuclear factor kappa-B kinase subunit beta	0	0	0	1
Polyphenol oxidase 2	0	1	0	2
Carbonic anhydrase 12	0	1	0	1
5'-AMP-activated protein kinase subunit beta-2	0	0	0	1
Polymerase acidic protein	0	0	1	1
Carbonic anhydrase 3	0	1	0	1
Stromelysin-1	0	1	1	2
Tyrosine-protein phosphatase YopH	0	1	0	1
High mobility group protein B1	0	0	1	1
Prolyl 4-hydroxylase subunit alpha-1	0	1	0	1
Tyrosine-protein phosphatase non-receptor type 1	0	1	0	3
Estrogen receptor	0	0	0	1
Acetylcholinesterase	0	1	0	1
Carbonic anhydrase 4	0	1	0	1
Carbonic anhydrase 6	0	1	0	1
Cystathionine gamma-lyase	0	1	0	1
Carbonic anhydrase 5A, mitochondrial	0	1	0	1
Carbonic anhydrase 7	0	1	0	1
5'-AMP-activated protein kinase subunit gamma-1	0	0	0	1
5'-AMP-activated protein kinase catalytic subunit alpha-2	0	0	0	1
Xanthine dehydrogenase/oxidase	0	1	0	1
5'-AMP-activated protein kinase catalytic subunit alpha-1	0	0	0	1
Carbonic anhydrase 9	0	1	0	1
Carbonic anhydrase	0	1	0	1
Nicotinate phosphoribosyltransferase	0	1	0	1
Ubiquitin-like domain-containing CTD phosphatase 1	0	1	0	1
Carbonic anhydrase 15	0	1	0	1
Carbonic anhydrase 13	0	1	0	1
5'-AMP-activated protein kinase subunit gamma-3	0	0	0	1
5'-AMP-activated protein kinase subunit gamma-2	0	0	0	1
Carbonic anhydrase 14	0	1	0	1
Carbonic anhydrase 5B, mitochondrial	0	1	0	1
5'-AMP-activated protein kinase subunit beta-1	0	0	0	1
90-kda heat shock protein beta HSP90 beta, partial	0	1	0	1
estrogen receptor beta isoform 1	0	1	0	1
heat shock protein HSP 90-alpha isoform 2	0	1	0	1
tyrosine-protein phosphatase non-receptor type 7 isoform 2	0	1	0	1
Dihydroxyacetone phosphate acyltransferase	0	0	0	1
30S ribosomal protein S6	0	1	0	1
30S ribosomal protein S7	0	1	0	1
50S ribosomal protein L15	0	1	0	1
Tetracycline resistance protein, class B	0	0	0	1
Muscarinic acetylcholine receptor M2	0	1	0	1
72 kDa type IV collagenase	0	1	0	1
50S ribosomal protein L10	0	1	0	1
50S ribosomal protein L11	0	1	0	1
50S ribosomal protein L7/L12	0	1	0	1
50S ribosomal protein L19	0	1	0	1
50S ribosomal protein L1	0	1	0	1
50S ribosomal protein L20	0	1	0	1
50S ribosomal protein L27	0	1	0	1
50S ribosomal protein L28	0	1	0	1
50S ribosomal protein L29	0	1	0	1
50S ribosomal protein L31	0	1	0	1
50S ribosomal protein L31 type B	0	1	0	1
50S ribosomal protein L32	0	1	0	1
50S ribosomal protein L33	0	1	0	1
50S ribosomal protein L34	0	1	0	1
50S ribosomal protein L35	0	1	0	1
50S ribosomal protein L36	0	1	0	1
30S ribosomal protein S10	0	1	0	1
30S ribosomal protein S11	0	1	0	1
30S ribosomal protein S12	0	1	0	1
30S ribosomal protein S13	0	1	0	1
30S ribosomal protein S16	0	1	0	1
30S ribosomal protein S18	0	1	0	1
30S ribosomal protein S19	0	1	0	1
30S ribosomal protein S20	0	1	0	1
30S ribosomal protein S2	0	1	0	1
30S ribosomal protein S3	0	1	0	1
30S ribosomal protein S4	0	1	0	1
30S ribosomal protein S5	0	1	0	1
30S ribosomal protein S8	0	1	0	1
30S ribosomal protein S9	0	1	0	1
50S ribosomal protein L13	0	1	0	1
50S ribosomal protein L14	0	1	0	1
50S ribosomal protein L16	0	1	0	1
50S ribosomal protein L23	0	1	0	1
30S ribosomal protein S15	0	1	0	1
Multidrug transporter MdfA	0	1	0	1
50S ribosomal protein L17	0	1	0	1
50S ribosomal protein L21	0	1	0	1
50S ribosomal protein L30	0	1	0	1
50S ribosomal protein L6	0	1	0	1
30S ribosomal protein S14	0	1	0	1
30S ribosomal protein S17	0	1	0	1
30S ribosomal protein S1	0	1	0	1
50S ribosomal protein L18	0	1	0	1
Neutrophil collagenase	0	1	0	1
Collagenase 3	0	1	0	1
Cannabinoid receptor 1	0	1	0	1
50S ribosomal protein L2	0	1	0	1
50S ribosomal protein L3	0	1	0	1
50S ribosomal protein L24	0	1	0	1
50S ribosomal protein L4	0	1	0	1
50S ribosomal protein L22	0	1	0	1
50S ribosomal protein L5	0	1	0	1
30S ribosomal protein S21	0	1	0	1
50S ribosomal protein L25	0	1	0	1
50S ribosomal protein L36 2	0	1	0	1
Integrase	0	1	0	1
Solute carrier family 22 member 11	0	0	0	1
Solute carrier family 22 member 7	0	0	0	1
streptokinase A precursor	0	0	1	1
Estrogen receptor	0	0	1	1
Estrogen receptor beta	0	0	1	1
acid sphingomyelinase	1	0	0	1
67.9K protein	1	0	0	1
HLA class I histocompatibility antigen, A alpha chain	0	0	1	1
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]

Synonyms(7)

Research Excerpts

Overview

Treatment

Research

Studies (61)

Protein Targets (397)

Bovine Digital Dermatitis

Synonyms(7)

Research Excerpts

Overview

Treatment

Research

Studies (61)

Drugs Studied (37)

Protein Targets (397)