Page last updated: 2024-09-27

Bone Marrow Failure Syndromes, Congenital

Inherited syndromes characterized by deficiency or absence of various blood cells due to mutations that affect HEMATOPOIETIC STEM CELLS development and proliferation.

Synonyms(10)

Synonym
IBMFS
Congenital Bone Marrow Failure Syndromes
Inherited BMF Syndrome
Congenital Bone Marrow Failure Syndrome
Inherited BMF Syndromes
Bone Marrow Failure Syndromes, Congenital
Inherited Bone Marrow Failure Syndrome
Inherited Bone Marrow Failure Syndromes
Bone Marrow Failure Syndromes, Inherited
CBMFS

Research Excerpts

Overview

ExcerptReference
"IBMFS are associated with high risk of myelodysplastic syndrome (MDS), acute myeloid leukemia (AML), and solid tumors."( Allegri, M; Api, M; Bezzerri, V; Cipolli, M; Corey, SJ; Fabrizzi, B, 2020)

Research

Studies (77)

TimeframeStudies, This Condition (%)All Conditions %
pre-19900 (0.00)23.3326
1990's0 (0.00)12.5806
2000's0 (0.00)18.1394
2010's51 (66.23)28.8240
2020's26 (33.77)9.53
DrugIndicatedRelationship StrengthStudiesTrials
acetylcarnitine0low10
benzene0low10
carnitine0medium261
3-hydroxybutyric acid0low10
lactic acid0low10
niacinamide0low10
palmitic acid0low10
pyruvic acid0low10
uric acid0low10
valproic acid0low10
apnea0low10
sevoflurane0low10
prednisolone0low20
lysine0low10
methylprednisolone0low10
thiophenes0low10
pyrazines0low10
hydrazine0medium21
fusarium0low10
acetylcysteine0low10
vidarabine0low10
tetradecanoylphorbol acetate0low10
s-adenosylmethionine0medium131
bezafibrate0medium61
silver0low10
triheptanoin0low20
valerates0low10
s-nitroso-n-acetylcysteine0low10
methotrexate0low10
2-ethylhydracrylic acid0low10
bortezomib0low10
povidone-iodine0low10
glycogen0low10
resveratrol0medium21
tacrolimus0low10
melphalan0low10
fludarabine0low20
3-methylglutaconic acid0low10
valinomycin0low10
alpha-chymotrypsin0low10
osteoprotegerin0low10
phenylephrine hydrochloride0low10
fumarates0low10
cysteine0low10
phosphocreatine0low10
etomoxir0low10
mocetinostat0low10
decanoylcarnitine0low10
oxadiazoles0low10
ptc 1240low10
calpain0low20
heme0low10
ascorbic acid0low10
guanosine triphosphate0low10
amg5310medium21
trypsinogen0low10

Protein Targets (611)

ProteinPotency MeasurementsInhibition MeasurementsActivation MeasurementsDrugs
Protein skinhead-10101
Monocarboxylate transporter 20202
Solute carrier family 22 member 200303
Solute carrier family 22 member 60303
glp-1 receptor, partial4004
TDP1 protein120012
geminin130013
Chain A, JmjC domain-containing histone demethylation protein 3A1001
Chain A, 2-oxoglutarate Oxygenase4004
Chain A, ATP-DEPENDENT DNA HELICASE Q11001
acetylcholinesterase6006
dopamine D1 receptor2002
15-lipoxygenase, partial3003
pregnane X receptor3003
phosphopantetheinyl transferase5005
RAR-related orphan receptor gamma120012
USP1 protein, partial5005
NFKB1 protein, partial1001
Microtubule-associated protein tau5005
Thrombopoietin1001
AR protein150015
regulator of G-protein signaling 42002
glucocorticoid receptor [Homo sapiens]120012
retinoic acid nuclear receptor alpha variant 1140014
retinoid X nuclear receptor alpha9009
farnesoid X nuclear receptor100010
estrogen nuclear receptor alpha190019
vitamin D (1,25- dihydroxyvitamin D3) receptor8008
arylsulfatase A3003
euchromatic histone-lysine N-methyltransferase 27007
Bloom syndrome protein isoform 15005
D(1A) dopamine receptor3003
thyroid hormone receptor beta isoform a3003
thyroid hormone receptor beta isoform 2110011
heat shock protein beta-13003
flap endonuclease 13003
peripheral myelin protein 226006
survival motor neuron protein isoform d5005
muscarinic acetylcholine receptor M11001
Histone deacetylase 30606
Solute carrier family 22 member 60101
Histone deacetylase 40404
Guanine nucleotide-binding protein G1001
Histone deacetylase 10606
Histone deacetylase 70404
Histone deacetylase 20606
Polyamine deacetylase HDAC100303
Histone deacetylase 11 0404
Ataxin-2110011
Histone deacetylase 80505
Histone deacetylase 60505
Histone deacetylase 90303
Histone deacetylase 50404
ATP-dependent phosphofructokinase4004
Luciferase5005
hypoxia-inducible factor 1 alpha subunit3003
estrogen receptor 2 (ER beta)7007
progesterone receptor9009
cytochrome P450 family 3 subfamily A polypeptide 4100010
EWS/FLI fusion protein8008
G7007
cytochrome P450 2D66006
peroxisome proliferator-activated receptor delta9009
peroxisome proliferator activated receptor gamma100010
nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105), isoform CRA_a2002
v-jun sarcoma virus 17 oncogene homolog (avian)3003
Histone H2A.x5005
nuclear factor erythroid 2-related factor 2 isoform 1120012
Solute carrier family 22 member 1 0101
Solute carrier organic anion transporter family member 2B1 0101
Interferon beta9009
HLA class I histocompatibility antigen, B alpha chain 7007
Replicase polyprotein 1ab0101
Replicase polyprotein 1ab0112
Thrombopoietin receptor0011
Potassium voltage-gated channel subfamily H member 20202
Sodium channel protein type 5 subunit alpha0101
Inositol hexakisphosphate kinase 17007
Solute carrier organic anion transporter family member 1B30102
Potassium voltage-gated channel subfamily D member 30101
Broad substrate specificity ATP-binding cassette transporter ABCG20203
Solute carrier organic anion transporter family member 1B10202
cytochrome P450 2C9, partial7007
thioredoxin reductase7007
ATAD5 protein, partial3003
estrogen-related nuclear receptor alpha150015
lamin isoform A-delta106006
neuropeptide S receptor isoform A1001
Chain A, Hyaluronidase, phage associated0101
GLI family zinc finger 39009
thioredoxin glutathione reductase2002
IDH16006
chromobox protein homolog 16006
nuclear factor erythroid 2-related factor 2 isoform 26006
lethal(3)malignant brain tumor-like protein 1 isoform I1001
lethal factor (plasmid)1001
Polyphenol oxidase 20202
Pancreatic alpha-amylase0202
Albumin0101
Urease0101
Prolyl 4-hydroxylase subunit alpha-10001
Tyrosinase0202
Alpha-2B adrenergic receptor0011
Spike glycoprotein6006
Hyaluronate lyase0101
Prolyl hydroxylase EGLN20001
Egl nine homolog 10001
Prolyl hydroxylase EGLN30001
Hypoxia-inducible factor 1-alpha inhibitor0001
Solute carrier family 23 member 10101
Chain A, Integrase0101
Chain A, Integrase0101
Chain A, T4 LYSOZYME0011
Chain A, GCN4P10011
Chain B, GCN4P10011
Chain C, GCN4P10011
Chain A, T4 LYSOZYME0011
Chain A, T4 LYSOZYME0011
Chain A, Replicase polyprotein 1ab0101
Chain A, 3C-like proteinase0101
thyroid stimulating hormone receptor1001
cellular tumor antigen p53 isoform a4004
Endolysin0011
Cellular tumor antigen p53130013
Integrin beta-34004
Integrin alpha-IIb4004
aldehyde dehydrogenase 1 family, member A14004
pregnane X nuclear receptor7007
Glutamate receptor ionotropic, NMDA 2D0011
Glutamate receptor ionotropic, NMDA 3B0011
Bile salt export pump0303
5-hydroxytryptamine receptor 40011
Bile salt export pump011011
Fatty acid-binding protein, liver0202
Muscarinic acetylcholine receptor M10011
Muscarinic acetylcholine receptor M30011
Muscarinic acetylcholine receptor M40011
Muscarinic acetylcholine receptor M50011
Muscarinic acetylcholine receptor M20011
Fatty acid-binding protein, intestinal0202
Peroxisome proliferator-activated receptor alpha0011
Peroxisome proliferator-activated receptor delta0011
Peroxisome proliferator-activated receptor gamma0011
Peroxisome proliferator-activated receptor gamma0011
Peroxisome proliferator-activated receptor delta0011
Glutamate receptor ionotropic, NMDA 10011
Peroxisome proliferator-activated receptor alpha1023
Glutamate receptor ionotropic, NMDA 2A0011
Glutamate receptor ionotropic, NMDA 2B0011
Glutamate receptor ionotropic, NMDA 2C0011
Glutamate receptor ionotropic, NMDA 3A0011
Chain H, Proteasome component PUP10101
Chain I, Proteasome component PUP30101
Chain K, Proteasome component PRE20101
Chain L, Proteasome component C50101
Chain K, Proteasome component PRE20101
Chain L, Proteasome component C50101
Proteasome subunit beta type-110101
Fumarate hydratase3003
PPM1D protein3003
caspase 7, apoptosis-related cysteine protease3003
nuclear receptor subfamily 1, group I, member 37007
polyprotein3003
caspase-33003
cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a100010
nuclear receptor subfamily 1, group I, member 25005
Caspase-73003
caspase-33003
26S proteasome non-ATPase regulatory subunit 110101
26S proteasome non-ATPase regulatory subunit 120101
26S proteasome non-ATPase regulatory subunit 140101
Proteasome subunit alpha type-70101
ATP-binding cassette sub-family C member 30707
Multidrug resistance-associated protein 40708
26S proteasome non-ATPase regulatory subunit 30101
Carbonic anhydrase 120202
Voltage-dependent calcium channel gamma-2 subunit6006
Prothrombin0101
Chymotrypsinogen A0101
Carbonic anhydrase 10202
Carbonic anhydrase 20213
Carbonic anhydrase 30202
Cathepsin B0101
Neutrophil elastase0101
Cathepsin G0202
Lysosomal protective protein0101
Chymotrypsinogen B0101
26S proteasome regulatory subunit 6A0101
Glutamate receptor 26006
Nuclear factor NF-kappa-B p105 subunit0202
Proteasome subunit beta type-10102
Carbonic anhydrase 40202
Carbonic anhydrase 60202
Chymase0101
Proteasome subunit alpha type-10101
Proteasome subunit alpha type-20101
Proteasome subunit alpha type-30101
Proteasome subunit alpha type-40101
Proteasome subunit beta type-80101
Proteasome subunit beta type-80101
Proteasome subunit beta type-90101
Proteasome subunit alpha type-50101
Proteasome subunit beta type-40101
Proteasome subunit beta type-60101
Proteasome subunit beta type-50203
Carbonic anhydrase 5A, mitochondrial0202
26S proteasome regulatory subunit 70101
Lon protease homolog, mitochondrial0101
Proteasome subunit beta type-100101
Carbonic anhydrase 70202
26S proteasome regulatory subunit 6B0101
26S proteasome non-ATPase regulatory subunit 80101
Proteasome subunit beta type-30101
Proteasome subunit beta type-20102
26S proteasome non-ATPase regulatory subunit 70101
26S proteasome non-ATPase regulatory subunit 40101
26S proteasome complex subunit SEM10101
Proteasome subunit alpha type-60101
26S proteasome regulatory subunit 40101
26S proteasome regulatory subunit 80101
26S proteasome regulatory subunit 10B0101
Beta-carbonic anhydrase 10101
Nuclear factor NF-kappa-B p100 subunit 0202
Transcription factor p650202
26S proteasome non-ATPase regulatory subunit 20101
26S proteasome non-ATPase regulatory subunit 60101
Proteasomal ubiquitin receptor ADRM10101
Carbonic anhydrase 90202
ATP-dependent Clp protease proteolytic subunit0112
Carbonic anhydrase 130202
NACHT, LRR and PYD domains-containing protein 3 0101
Proteasome subunit alpha-type 80101
Canalicular multispecific organic anion transporter 10707
ATPase family AAA domain-containing protein 5100010
Proteasome subunit beta type-70101
26S proteasome non-ATPase regulatory subunit 10101
Carbonic anhydrase 150202
Carbonic anhydrase 140202
26S proteasome non-ATPase regulatory subunit 130101
Carbonic anhydrase 5B, mitochondrial0202
Solute carrier family 22 member 50001
Solute carrier family 22 member 50001
Solute carrier family 22 member 160001
Solute carrier family 22 member 210001
Solute carrier family 22 member 50001
Chain A, Beta-lactamase2002
Smad32002
hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)5005
corticotropin-releasing hormone receptor 20112
67.9K protein5005
corticotropin releasing factor-binding protein0112
glycogen synthase kinase-3 beta isoform 10022
urokinase-type plasminogen activator precursor4004
plasminogen precursor4004
urokinase plasminogen activator surface receptor precursor4004
5'-nucleotidase0101
Adenosine receptor A30101
Adenosine deaminase 0002
Chain A, Uracil Phosphoribosyltransferase0011
Chain B, Uracil Phosphoribosyltransferase0011
Chain C, Uracil Phosphoribosyltransferase0011
2-dehydropantoate 2-reductase0011
Ras-related protein Rab-7a0011
4-galactosyl-N-acetylglucosaminide 3-alpha-L-fucosyltransferase 90202
thyroid stimulating hormone receptor3003
Chain A, Ribulose-1,5 bisphosphate carboxylase/oxygenase large subunit N-methyltransferase, chloroplast0101
Chain A, Ribulose-1,5 bisphosphate carboxylase/oxygenase large subunit N-methyltransferase, chloroplast0101
potassium voltage-gated channel subfamily H member 2 isoform d3003
Glutathione reductase, mitochondrial0202
Cationic amino acid transporter 30101
Chain A, TYROSYL-DNA PHOSPHODIESTERASE4004
GLS protein2002
glucocerebrosidase1001
aryl hydrocarbon receptor5005
importin subunit beta-1 isoform 12002
snurportin-12002
cytochrome P450 3A4 isoform 12002
Gamma-aminobutyric acid receptor subunit pi2002
Gamma-aminobutyric acid receptor subunit beta-12002
Gamma-aminobutyric acid receptor subunit delta2002
Gamma-aminobutyric acid receptor subunit gamma-22002
Gamma-aminobutyric acid receptor subunit alpha-52002
Gamma-aminobutyric acid receptor subunit alpha-32002
Gamma-aminobutyric acid receptor subunit gamma-12002
Gamma-aminobutyric acid receptor subunit alpha-22002
Gamma-aminobutyric acid receptor subunit alpha-42002
Gamma-aminobutyric acid receptor subunit gamma-32002
Gamma-aminobutyric acid receptor subunit alpha-62002
Nuclear receptor ROR-gamma3003
Gamma-aminobutyric acid receptor subunit alpha-12002
Gamma-aminobutyric acid receptor subunit beta-32002
Gamma-aminobutyric acid receptor subunit beta-22002
TAR DNA-binding protein 432002
Large neutral amino acids transporter small subunit 1 0101
GABA theta subunit2002
Gamma-aminobutyric acid receptor subunit epsilon2002
Chain A, MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASE4004
Chain B, DIHYDROFOLATE REDUCTASE0011
Chain B, DIHYDROFOLATE REDUCTASE0011
Chain B, DIHYDROFOLATE REDUCTASE0011
Chain A, HADH2 protein2002
Chain B, HADH2 protein2002
Chain A, Ferritin light chain2002
acid sphingomyelinase1001
ClpP2002
Thymidylate synthase 0101
alpha-galactosidase1001
Thymidylate synthase 0101
polyunsaturated fatty acid lipoxygenase ALOX121001
15-hydroxyprostaglandin dehydrogenase [NAD(+)] isoform 12002
vitamin D3 receptor isoform VDRA1001
transcriptional regulator ERG isoform 31001
DNA polymerase beta2002
nuclear receptor coactivator 1 isoform 1 [Homo sapiens]0101
peptidyl-prolyl cis-trans isomerase NIMA-interacting 11001
DNA polymerase eta isoform 11001
DNA polymerase iota isoform a (long)2002
transactivating tegument protein VP16 [Human herpesvirus 1]0101
DNA polymerase kappa isoform 14004
M-phase phosphoprotein 82002
muscleblind-like protein 1 isoform 13003
histone acetyltransferase KAT2A isoform 12002
caspase-1 isoform alpha precursor1001
nuclear receptor coactivator 3 isoform a0101
Toll-like receptor 40101
Fatty-acid amide hydrolase 10101
ATP-binding cassette sub-family C member 30102
Dihydrofolate reductase0203
Dihydrofolate reductase0203
Dihydrofolate reductase 0101
Dihydrofolate reductase0101
Dihydrofolate reductase0101
Dihydrofolate reductase0203
Thymidylate synthase0101
Tyrosine-protein kinase ABL10113
Thymidylate synthase0202
Bifunctional dihydrofolate reductase-thymidylate synthase0101
Thymidylate synthase0202
5-hydroxytryptamine receptor 2C0102
High mobility group protein B10011
Dihydrofolate reductase0101
Thymidylate synthase0101
Dihydrofolate reductase0224
Glucose-6-phosphate 1-dehydrogenase0101
Bifunctional dihydrofolate reductase-thymidylate synthase0101
Folate receptor beta0101
5-hydroxytryptamine receptor 2A0101
Cytochrome P450 11B1, mitochondrial 0101
Folate receptor alpha0101
Dihydrofolate reductase0202
Histidine decarboxylase0101
Trifunctional purine biosynthetic protein adenosine-30101
Cyclin-dependent kinase 20011
Bifunctional purine biosynthesis protein ATIC0202
Multidrug resistance-associated protein 1 0001
Delta-type opioid receptor0101
Mu-type opioid receptor0101
Kappa-type opioid receptor0101
Reduced folate transporter0202
Folylpolyglutamate synthase, mitochondrial0103
6-phosphogluconate dehydrogenase, decarboxylating0101
Caspase-71001
Solute carrier organic anion transporter family member 1A30001
Dihydrofolate reductase0101
Pteridine reductase 10101
Folylpolyglutamate synthase, mitochondrial0103
Bifunctional dihydrofolate reductase-thymidylate synthase0101
Bifunctional dihydrofolate reductase-thymidylate synthase0101
Solute carrier family 22 member 60002
Canalicular multispecific organic anion transporter 10102
Trifunctional purine biosynthetic protein adenosine-30101
Dihydrofolate reductase 0101
Solute carrier family 22 member 80102
Dihydrofolate reductase0101
ATP-binding cassette sub-family C member 110001
Proton-coupled folate transporter0101
Multidrug resistance associated protein0102
Solute carrier family 22 member 110001
Protein-arginine deiminase type-40101
nonstructural protein 11001
bromodomain adjacent to zinc finger domain 2B1001
Nuclear receptor subfamily 1 group I member 20022
Glucocorticoid receptor04110
Glycine receptor subunit alpha-10404
Androgen receptor0303
Glycine receptor subunit beta0404
Glycine receptor subunit alpha-20404
Glycine receptor subunit alpha-30404
Nuclear receptor subfamily 1 group I member 20011
Nuclear receptor corepressor 10101
Integrin beta-10101
Cytochrome P450 3A40404
Leukotriene A-4 hydrolase0202
Cytochrome P450 2D60101
Integrin alpha-40101
Cytochrome P450 2C190202
Nuclear receptor corepressor 20101
Chain A, NAD-dependent deacetylase0101
activating transcription factor 61001
Poly [ADP-ribose] polymerase 20101
NAD-dependent histone deacetylase SIR20101
Coagulation factor VII0101
Poly [ADP-ribose] polymerase 10101
Tissue factor0202
Cytochrome P450 3A50202
NAD-dependent protein deacetylase HST20101
Fatty-acid amide hydrolase 10101
Protein mono-ADP-ribosyltransferase PARP150101
NAD(+) hydrolase SARM10101
NAD-dependent protein deacetylase sirtuin-20112
NAD-dependent protein deacetylase sirtuin-60101
NAD-dependent protein deacetylase sirtuin-10114
NAD-dependent protein deacetylase sirtuin-3, mitochondrial0112
NAD-dependent protein deacylase sirtuin-5, mitochondrial0202
NAD-dependent protein deacetylase 0101
Chain A, Fatty acid-binding protein, adipocyte0101
Acetylcholinesterase0202
Toll-like receptor 20101
Prostaglandin G/H synthase 1 0101
Fatty acid-binding protein, adipocyte0213
Tyrosine-protein phosphatase non-receptor type 10202
Prostaglandin G/H synthase 20202
Fatty acid-binding protein 50213
Olfactory receptor 51E20011
Transient receptor potential cation channel subfamily V member 20101
GALC protein1001
beta-2 adrenergic receptor1001
lysosomal alpha-glucosidase preproprotein2002
mu-type opioid receptor isoform MOR-10011
Vpr1001
5-hydroxytryptamine receptor 2A0011
Neuronal acetylcholine receptor subunit alpha-41102
Neuronal acetylcholine receptor subunit beta-21102
luciferase0001
Estrogen receptor0303
Progesterone receptor0203
Glucocorticoid receptor0112
Glucocorticoid receptor0011
Corticosteroid-binding globulin0101
Mineralocorticoid receptor 0213
Androgen receptor0202
Cytochrome P450 2C9 0202
Glutamine synthetase0011
Histamine H1 receptor0022
Prostaglandin G/H synthase 20202
Nociceptin receptor0011
Cytochrome P450 2J20101
Estrogen receptor beta0202
SMAD family member 22002
SMAD family member 32002
histone deacetylase 9 isoform 32002
nuclear receptor ROR-gamma isoform 14004
Flavin reductase (NADPH)0011
Monocarboxylate transporter 40001
Monocarboxylate transporter 20001
Monocarboxylate transporter 10001
C-terminal-binding protein 20101
Prolyl 4-hydroxylase0101
Solute carrier organic anion transporter family member 2A10101
Alpha-ketoglutarate-dependent dioxygenase FTO0101
Chain A, Troponin C, slow skeletal and cardiac muscles0011
Chain A, Leukotriene A-4 hydrolase0101
Chain A, Leukotriene A-4 hydrolase0101
Chain A, Leukotriene A-4 hydrolase0101
Chain A, Leukotriene A-4 hydrolase0101
Chain A, Leukotriene A-4 hydrolase0101
Chain A, Leukotriene A-4 hydrolase0101
Chain A, Leukotriene A-4 hydrolase0101
Chain A, Leukotriene A-4 hydrolase0101
Chain A, Leukotriene A-4 hydrolase0101
Chain A, Leukotriene A-4 hydrolase0101
Chain A, Leukotriene A-4 hydrolase0101
Chain A, Leukotriene A-4 hydrolase0101
Chain A, Leukotriene A-4 hydrolase0101
Chain A, Leukotriene A-4 hydrolase0101
Chain A, Leukotriene A-4 hydrolase0101
Chain A, Leukotriene A-4 hydrolase0101
Chain A, Leukotriene A-4 hydrolase0101
BRCA11001
Parkin1001
P531001
pyruvate kinase1001
M18 aspartyl aminopeptidase0101
cathepsin L10101
heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)2002
hexokinase-4 isoform 11001
NPC intracellular cholesterol transporter 1 precursor1001
peripheral myelin protein 22 isoform 11001
parathyroid hormone/parathyroid hormone-related peptide receptor precursor1001
glucokinase regulatory protein1001
huntingtin isoform 21001
atrial natriuretic peptide receptor 2 precursor1001
nuclear factor NF-kappa-B p105 subunit isoform 10011
ras-related protein Rab-9A1001
serine/threonine-protein kinase mTOR isoform 11001
FAD-linked sulfhydryl oxidase ALR0001
Vif0101
DNA dC->dU-editing enzyme APOBEC-3G isoform 10101
transcription factor p65 isoform 10011
serine/threonine-protein kinase 33 isoform a0011
POsterior Segregation0011
Aryl hydrocarbon receptor0101
Estrogen receptor beta0011
Polyunsaturated fatty acid lipoxygenase ALOX15B1001
Lysine-specific histone demethylase 1A0101
Transient receptor potential cation channel subfamily A member 10112
Myc proto-oncogene protein0102
Transthyretin0011
Cytochrome P450 1A10101
Amyloid-beta precursor protein0112
Cytochrome P450 1A20101
Prostaglandin G/H synthase 10112
Tyrosine-protein kinase Lck0101
Cholinesterase0101
Cathepsin D0101
Aldo-keto reductase family 1 member B10303
ATP-dependent translocase ABCB10204
Luciferin 4-monooxygenase0112
DNA polymerase alpha catalytic subunit0101
Polyunsaturated fatty acid 5-lipoxygenase0101
Breakpoint cluster region protein0102
Tyrosinase0202
Aromatase0202
Ornithine decarboxylase0101
Ribosyldihydronicotinamide dehydrogenase [quinone]0213
Protein kinase C alpha type0123
5-hydroxytryptamine receptor 1A0001
Estrogen receptor0011
Amine oxidase [flavin-containing] A0101
Endothelin receptor type B1001
Acetylcholinesterase0101
Prostaglandin G/H synthase 10101
Sucrase-isomaltase, intestinal0101
Sodium-dependent noradrenaline transporter 0213
Endothelin-1 receptor1001
Amine oxidase [flavin-containing] B0101
Dipeptidyl peptidase 40202
ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 10101
Nitric oxide synthase, inducible0101
Cannabinoid receptor 10101
Histamine H2 receptor1001
D(1A) dopamine receptor1001
Alpha-glucosidase MAL120101
Cholinesterase0101
Inositol monophosphatase 11001
Squalene synthase0101
cAMP-specific 3',5'-cyclic phosphodiesterase 4B0001
Bcl-2-like protein 10101
Serine/threonine-protein kinase PAK 10101
Nuclear factor erythroid 2-related factor 20012
Cytochrome P450 1B10202
N1L 0101
NAD(P)H dehydrogenase [quinone] 10002
Tubulin beta-2B chain0101
Lysosomal alpha-glucosidase0101
Transient receptor potential cation channel subfamily A member 10101
Similar to alpha-tubulin isoform 1 0101
Similar to alpha-tubulin isoform 1 0101
Rap guanine nucleotide exchange factor 41001
Prenyltransferase homolog0001
Zinc finger protein mex-50011
large T antigen0101
Met repressor 0022
Protein arginine N-methyltransferase 50011
Histone H3K27 methylase0001
Phenylethanolamine N-methyltransferase0012
S-adenosylmethionine decarboxylase proenzyme0102
Protein-L-isoaspartate(D-aspartate) O-methyltransferase0101
Catechol O-methyltransferase0001
Protein arginine N-methyltransferase 10101
Methylosome protein 500011
UDP-glucuronosyltransferase 2B70103
UDP-glucuronosyltransferase 1A40001
Serine/threonine-protein kinase mTOR0101
Peptidyl-prolyl cis-trans isomerase FKBP1A0213
Peptidyl-prolyl cis-trans isomerase FKBP1B0011
Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform0101
Peptidyl-prolyl cis-trans isomerase FKBP50101
Splicing factor 3B subunit 30101
Serine/threonine-protein kinase D30011
Protein kinase C gamma type0112
Protein kinase C beta type0112
Beta-1 adrenergic receptor0101
Protein kinase C eta type0011
Protein kinase C iota type0011
Protein kinase C epsilon type0112
Protein kinase C theta type0011
Protein kinase C zeta type0011
Protein kinase C delta type0112
Serine/threonine-protein kinase D10011
Ras guanyl-releasing protein 30011
Chain A, Glycogen phosphorylase, liver form0011
Chain A, glycogen phosphorylase, liver form0011
Chain A, Glycogen phosphorylase, liver form0011
Chain A, Glycogen phosphorylase, liver form0011
Solute carrier family 2, facilitated glucose transporter member 90112
Guanine deaminase0101
Carbonic anhydrase0101
Cocaine esterase0101
UDP-glucuronosyltransferase 1A90001
Cytochrome P450 2A60101
Aldo-keto reductase family 1 member A10101
UDP-glucuronosyltransferase 1-60001
Liver carboxylesterase 10101
Aldo-keto reductase family 1 member A10101
Aldo-keto reductase family 1 member A10101
Aldo-keto reductase family 1 member B70101
Sigma non-opioid intracellular receptor 10101
Thymidine kinase, cytosolic0001
Adenosylhomocysteinase0101
RNA-directed RNA polymerase 0112
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]