| Protein | Potency Measurements | Inhibition Measurements | Activation Measurements | Drugs |
|---|
| estrogen nuclear receptor alpha | 4 | 0 | 0 | 4 |
| peripheral myelin protein 22 | 3 | 0 | 0 | 3 |
| histone acetyltransferase KAT2A isoform 1 | 2 | 0 | 0 | 2 |
| lamin isoform A-delta10 | 4 | 0 | 0 | 4 |
| ATP-binding cassette sub-family C member 3 | 0 | 4 | 0 | 4 |
| Multidrug resistance-associated protein 4 | 0 | 4 | 0 | 4 |
| Bile salt export pump | 0 | 4 | 0 | 4 |
| Canalicular multispecific organic anion transporter 1 | 0 | 4 | 0 | 4 |
| Aminoglycoside 3'-phosphotransferase | 0 | 0 | 0 | 1 |
| ATP-dependent phosphofructokinase | 1 | 0 | 0 | 1 |
| Chain A, JmjC domain-containing histone demethylation protein 3A | 3 | 0 | 0 | 3 |
| Chain A, BCL-2-RELATED PROTEIN A1 | 0 | 0 | 1 | 1 |
| Chain A, Cruzipain | 1 | 0 | 0 | 1 |
| Luciferase | 1 | 0 | 0 | 1 |
| acid sphingomyelinase | 1 | 0 | 0 | 1 |
| interleukin 8 | 2 | 0 | 0 | 2 |
| acetylcholinesterase | 1 | 0 | 0 | 1 |
| PAX8 | 0 | 0 | 0 | 1 |
| glp-1 receptor, partial | 2 | 0 | 0 | 2 |
| 15-lipoxygenase, partial | 1 | 0 | 0 | 1 |
| pregnane X receptor | 1 | 0 | 0 | 1 |
| phosphopantetheinyl transferase | 2 | 0 | 0 | 2 |
| hypoxia-inducible factor 1 alpha subunit | 1 | 0 | 0 | 1 |
| RAR-related orphan receptor gamma | 1 | 0 | 0 | 1 |
| SMAD family member 2 | 1 | 0 | 0 | 1 |
| USP1 protein, partial | 2 | 0 | 0 | 2 |
| SMAD family member 3 | 1 | 0 | 0 | 1 |
| TDP1 protein | 4 | 0 | 0 | 4 |
| GLI family zinc finger 3 | 2 | 0 | 0 | 2 |
| AR protein | 1 | 0 | 0 | 1 |
| caspase 7, apoptosis-related cysteine protease | 1 | 0 | 0 | 1 |
| hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 2 | 0 | 0 | 2 |
| PINK1 | 1 | 0 | 0 | 1 |
| thyroid stimulating hormone receptor | 2 | 0 | 0 | 2 |
| estrogen receptor 2 (ER beta) | 1 | 0 | 0 | 1 |
| nuclear receptor subfamily 1, group I, member 3 | 1 | 0 | 0 | 1 |
| progesterone receptor | 1 | 0 | 0 | 1 |
| cytochrome P450 family 3 subfamily A polypeptide 4 | 3 | 0 | 0 | 3 |
| glucocorticoid receptor [Homo sapiens] | 2 | 0 | 0 | 2 |
| retinoic acid nuclear receptor alpha variant 1 | 2 | 0 | 0 | 2 |
| retinoid X nuclear receptor alpha | 2 | 0 | 0 | 2 |
| estrogen-related nuclear receptor alpha | 2 | 0 | 0 | 2 |
| farnesoid X nuclear receptor | 1 | 0 | 0 | 1 |
| pregnane X nuclear receptor | 1 | 0 | 0 | 1 |
| G | 2 | 0 | 0 | 2 |
| cytochrome P450 2D6 | 2 | 0 | 0 | 2 |
| 67.9K protein | 2 | 0 | 0 | 2 |
| glucocerebrosidase | 1 | 0 | 0 | 1 |
| Parkin | 1 | 0 | 0 | 1 |
| peroxisome proliferator-activated receptor delta | 2 | 0 | 0 | 2 |
| peroxisome proliferator activated receptor gamma | 1 | 0 | 0 | 1 |
| vitamin D (1,25- dihydroxyvitamin D3) receptor | 1 | 0 | 0 | 1 |
| heat shock protein 90 | 0 | 0 | 1 | 1 |
| caspase-3 | 1 | 0 | 0 | 1 |
| IDH1 | 2 | 0 | 0 | 2 |
| euchromatic histone-lysine N-methyltransferase 2 | 3 | 0 | 0 | 3 |
| calcineurin A1, putative | 0 | 0 | 1 | 1 |
| aryl hydrocarbon receptor | 1 | 0 | 0 | 1 |
| cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a | 1 | 0 | 0 | 1 |
| thyroid stimulating hormone receptor | 2 | 0 | 0 | 2 |
| activating transcription factor 6 | 1 | 0 | 0 | 1 |
| nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105), isoform CRA_a | 1 | 0 | 0 | 1 |
| v-jun sarcoma virus 17 oncogene homolog (avian) | 1 | 0 | 0 | 1 |
| Histone H2A.x | 1 | 0 | 0 | 1 |
| cytochrome P450 2D6 isoform 1 | 2 | 0 | 0 | 2 |
| hepatocyte nuclear factor 4-alpha isoform 2 | 0 | 1 | 0 | 1 |
| cellular tumor antigen p53 isoform a | 1 | 0 | 0 | 1 |
| cytochrome P450 2C19 precursor | 1 | 0 | 0 | 1 |
| cytochrome P450 2C9 precursor | 1 | 0 | 0 | 1 |
| perilipin-5 | 0 | 1 | 0 | 1 |
| thyroid hormone receptor beta isoform a | 1 | 0 | 0 | 1 |
| perilipin-1 | 0 | 1 | 0 | 1 |
| nuclear factor erythroid 2-related factor 2 isoform 2 | 1 | 0 | 0 | 1 |
| potassium voltage-gated channel subfamily H member 2 isoform d | 2 | 0 | 0 | 2 |
| transcriptional regulator ERG isoform 3 | 2 | 0 | 0 | 2 |
| thyroid hormone receptor beta isoform 2 | 3 | 0 | 0 | 3 |
| heat shock protein beta-1 | 1 | 0 | 0 | 1 |
| huntingtin isoform 2 | 1 | 0 | 0 | 1 |
| importin subunit beta-1 isoform 1 | 2 | 0 | 0 | 2 |
| mitogen-activated protein kinase 1 | 2 | 0 | 0 | 2 |
| ubiquitin-conjugating enzyme E2 N | 0 | 1 | 0 | 1 |
| nuclear factor NF-kappa-B p105 subunit isoform 1 | 1 | 0 | 0 | 1 |
| flap endonuclease 1 | 1 | 0 | 0 | 1 |
| protein AF-9 isoform a | 0 | 0 | 0 | 1 |
| snurportin-1 | 2 | 0 | 0 | 2 |
| melanocortin receptor 4 | 0 | 1 | 0 | 1 |
| nuclear factor erythroid 2-related factor 2 isoform 1 | 2 | 0 | 0 | 2 |
| CAAX prenyl protease | 0 | 0 | 0 | 1 |
| urokinase-type plasminogen activator precursor | 1 | 0 | 0 | 1 |
| plasminogen precursor | 1 | 0 | 0 | 1 |
| bcl-2-related protein A1 | 0 | 1 | 0 | 1 |
| urokinase plasminogen activator surface receptor precursor | 1 | 0 | 0 | 1 |
| nuclear receptor ROR-gamma isoform 1 | 1 | 0 | 0 | 1 |
| geminin | 4 | 0 | 0 | 4 |
| 1-acylglycerol-3-phosphate O-acyltransferase ABHD5 isoform a | 0 | 1 | 0 | 1 |
| DNA polymerase kappa isoform 1 | 1 | 0 | 0 | 1 |
| cytochrome P450 3A4 isoform 1 | 2 | 0 | 0 | 2 |
| glycogen synthase kinase-3 alpha | 0 | 0 | 0 | 1 |
| hexokinase HKDC1 | 0 | 1 | 0 | 1 |
| DNA repair protein RAD52 homolog isoform a | 0 | 0 | 0 | 1 |
| bcl-2-like protein 11 isoform 1 | 0 | 0 | 1 | 1 |
| lethal factor (plasmid) | 1 | 0 | 0 | 1 |
| Gamma-aminobutyric acid receptor subunit pi | 2 | 0 | 0 | 2 |
| Synaptojanin-2 | 0 | 1 | 0 | 1 |
| Solute carrier family 22 member 2 | 0 | 1 | 0 | 1 |
| Solute carrier family 22 member 1 | 0 | 1 | 0 | 1 |
| Polyunsaturated fatty acid lipoxygenase ALOX15B | 1 | 0 | 0 | 1 |
| Synaptojanin-1 | 0 | 1 | 0 | 1 |
| Solute carrier family 22 member 3 | 0 | 1 | 0 | 1 |
| Voltage-dependent calcium channel gamma-2 subunit | 1 | 0 | 0 | 1 |
| Glutathione reductase, mitochondrial | 0 | 1 | 0 | 2 |
| Interferon beta | 3 | 0 | 0 | 3 |
| HLA class I histocompatibility antigen, B alpha chain | 2 | 0 | 0 | 2 |
| Cellular tumor antigen p53 | 1 | 0 | 0 | 1 |
| Integrin beta-3 | 1 | 0 | 0 | 1 |
| 72 kDa type IV collagenase | 0 | 1 | 0 | 1 |
| Integrin alpha-IIb | 1 | 0 | 0 | 1 |
| Matrix metalloproteinase-9 | 0 | 1 | 0 | 1 |
| Gamma-aminobutyric acid receptor subunit beta-1 | 2 | 0 | 0 | 2 |
| Gamma-aminobutyric acid receptor subunit delta | 2 | 0 | 0 | 2 |
| Gamma-aminobutyric acid receptor subunit gamma-2 | 2 | 0 | 0 | 2 |
| Glutamate receptor 2 | 1 | 0 | 0 | 1 |
| Gamma-aminobutyric acid receptor subunit alpha-5 | 2 | 0 | 0 | 2 |
| Gamma-aminobutyric acid receptor subunit alpha-3 | 2 | 0 | 0 | 2 |
| Gamma-aminobutyric acid receptor subunit gamma-1 | 2 | 0 | 0 | 2 |
| Gamma-aminobutyric acid receptor subunit alpha-2 | 2 | 0 | 0 | 2 |
| Gamma-aminobutyric acid receptor subunit alpha-4 | 2 | 0 | 0 | 2 |
| Gamma-aminobutyric acid receptor subunit gamma-3 | 2 | 0 | 0 | 2 |
| Trypanothione reductase | 0 | 1 | 0 | 1 |
| Gamma-aminobutyric acid receptor subunit alpha-6 | 2 | 0 | 0 | 2 |
| Alpha-synuclein | 1 | 0 | 0 | 1 |
| Histamine H2 receptor | 1 | 0 | 0 | 1 |
| Nuclear receptor ROR-gamma | 2 | 0 | 0 | 2 |
| Spike glycoprotein | 3 | 0 | 0 | 3 |
| Gamma-aminobutyric acid receptor subunit alpha-1 | 2 | 0 | 0 | 2 |
| Gamma-aminobutyric acid receptor subunit beta-3 | 2 | 0 | 0 | 2 |
| Gamma-aminobutyric acid receptor subunit beta-2 | 2 | 0 | 0 | 2 |
| TAR DNA-binding protein 43 | 2 | 0 | 0 | 2 |
| Peroxisomal N(1)-acetyl-spermine/spermidine oxidase | 0 | 1 | 0 | 1 |
| Multidrug and toxin extrusion protein 2 | 0 | 1 | 0 | 1 |
| Rap guanine nucleotide exchange factor 4 | 1 | 0 | 0 | 1 |
| GABA theta subunit | 2 | 0 | 0 | 2 |
| Inositol hexakisphosphate kinase 1 | 2 | 0 | 0 | 2 |
| Multidrug and toxin extrusion protein 1 | 0 | 2 | 0 | 2 |
| ATPase family AAA domain-containing protein 5 | 1 | 0 | 0 | 1 |
| Ataxin-2 | 1 | 0 | 0 | 1 |
| Gamma-aminobutyric acid receptor subunit epsilon | 2 | 0 | 0 | 2 |
| Spermine oxidase | 0 | 1 | 0 | 1 |
| cytochrome P450 2C9, partial | 2 | 0 | 0 | 2 |
| vitamin D3 receptor isoform VDRA | 1 | 0 | 0 | 1 |
| chromobox protein homolog 1 | 2 | 0 | 0 | 2 |
| mitogen-activated protein kinase kinase kinase kinase 2 isoform 1 | 0 | 0 | 1 | 1 |
| eyes absent homolog 2 isoform a | 1 | 0 | 0 | 1 |
| GTP-binding nuclear protein Ran isoform 1 | 1 | 0 | 0 | 1 |
| streptokinase A precursor | 0 | 0 | 3 | 3 |
| mitogen-activated protein kinase kinase kinase 3 isoform 1 | 0 | 0 | 1 | 1 |
| Estrogen receptor | 0 | 0 | 1 | 1 |
| ATP-dependent translocase ABCB1 | 0 | 1 | 0 | 2 |
| Spike glycoprotein | 0 | 0 | 1 | 1 |
| 5-hydroxytryptamine receptor 1A | 0 | 0 | 1 | 1 |
| Cruzipain | 0 | 1 | 0 | 1 |
| C-terminal-binding protein 1 | 1 | 0 | 0 | 1 |
| Estrogen receptor beta | 0 | 0 | 1 | 1 |
| Broad substrate specificity ATP-binding cassette transporter ABCG2 | 0 | 1 | 0 | 1 |
| Chain A, 2-oxoglutarate Oxygenase | 1 | 0 | 0 | 1 |
| thioredoxin reductase | 1 | 0 | 0 | 1 |
| EWS/FLI fusion protein | 1 | 0 | 0 | 1 |
| Replicase polyprotein 1ab | 0 | 1 | 0 | 1 |
| CAAX prenyl protease 2 isoform 2 | 0 | 0 | 0 | 1 |
| DNA polymerase beta | 1 | 0 | 0 | 1 |
| Bile salt export pump | 0 | 1 | 0 | 1 |
| Tubulin beta-4A chain | 0 | 1 | 0 | 1 |
| Tubulin beta chain | 0 | 1 | 0 | 1 |
| Tubulin alpha-3C chain | 0 | 1 | 0 | 1 |
| Tubulin alpha-1B chain | 0 | 1 | 0 | 1 |
| Tubulin alpha-4A chain | 0 | 1 | 0 | 1 |
| Tubulin beta-4B chain | 0 | 1 | 0 | 1 |
| Fatty-acid amide hydrolase 1 | 0 | 1 | 0 | 1 |
| DNA gyrase subunit A | 0 | 1 | 0 | 1 |
| DNA primase | 0 | 1 | 0 | 1 |
| Potassium voltage-gated channel subfamily H member 2 | 0 | 2 | 0 | 2 |
| Tubulin beta-3 chain | 0 | 1 | 0 | 1 |
| Tubulin beta-2A chain | 0 | 1 | 0 | 1 |
| Tubulin beta-8 chain | 0 | 1 | 0 | 1 |
| Tubulin alpha-3E chain | 0 | 1 | 0 | 1 |
| Tubulin alpha-1A chain | 0 | 1 | 0 | 1 |
| Tubulin alpha-1C chain | 0 | 1 | 0 | 1 |
| Tubulin beta-6 chain | 0 | 1 | 0 | 1 |
| Tubulin beta-2B chain | 0 | 1 | 0 | 1 |
| Tubulin beta-1 chain | 0 | 1 | 0 | 1 |
| Solute carrier family 22 member 3 | 0 | 1 | 0 | 1 |
| Amine oxidase [flavin-containing] B | 0 | 1 | 0 | 1 |
| Sodium-dependent noradrenaline transporter | 0 | 0 | 1 | 1 |
| Sodium-dependent serotonin transporter | 0 | 0 | 1 | 1 |
| Amine oxidase [flavin-containing] B | 0 | 1 | 0 | 1 |
| Synaptic vesicular amine transporter | 0 | 1 | 0 | 1 |
| Trace amine-associated receptor 1 | 0 | 0 | 1 | 1 |
| Trace amine-associated receptor 1 | 0 | 0 | 1 | 1 |
| Trace amine-associated receptor 1 | 0 | 0 | 1 | 1 |
| Trace amine-associated receptor 1 | 0 | 0 | 1 | 1 |
| Sigma non-opioid intracellular receptor 1 | 0 | 1 | 0 | 1 |
| PPM1D protein | 1 | 0 | 0 | 1 |
| nuclear receptor subfamily 1, group I, member 2 | 1 | 0 | 0 | 1 |
| twin arginine protein translocation system - TatA protein | 0 | 0 | 0 | 1 |
| 30S ribosomal protein S6 | 0 | 1 | 0 | 1 |
| 30S ribosomal protein S7 | 0 | 1 | 0 | 1 |
| 50S ribosomal protein L15 | 0 | 1 | 0 | 1 |
| Cytochrome P450 3A4 | 0 | 1 | 0 | 1 |
| 50S ribosomal protein L10 | 0 | 1 | 0 | 1 |
| 50S ribosomal protein L11 | 0 | 1 | 0 | 1 |
| 50S ribosomal protein L7/L12 | 0 | 1 | 0 | 1 |
| 50S ribosomal protein L19 | 0 | 1 | 0 | 1 |
| 50S ribosomal protein L1 | 0 | 1 | 0 | 1 |
| 50S ribosomal protein L20 | 0 | 1 | 0 | 1 |
| 50S ribosomal protein L27 | 0 | 1 | 0 | 1 |
| 50S ribosomal protein L28 | 0 | 1 | 0 | 1 |
| 50S ribosomal protein L29 | 0 | 1 | 0 | 1 |
| 50S ribosomal protein L31 | 0 | 1 | 0 | 1 |
| 50S ribosomal protein L31 type B | 0 | 1 | 0 | 1 |
| 50S ribosomal protein L32 | 0 | 1 | 0 | 1 |
| 50S ribosomal protein L33 | 0 | 1 | 0 | 1 |
| 50S ribosomal protein L34 | 0 | 1 | 0 | 1 |
| 50S ribosomal protein L35 | 0 | 1 | 0 | 1 |
| 50S ribosomal protein L36 | 0 | 1 | 0 | 1 |
| 30S ribosomal protein S10 | 0 | 1 | 0 | 1 |
| 30S ribosomal protein S11 | 0 | 1 | 0 | 1 |
| 30S ribosomal protein S12 | 0 | 1 | 0 | 1 |
| 30S ribosomal protein S13 | 0 | 1 | 0 | 1 |
| 30S ribosomal protein S16 | 0 | 1 | 0 | 1 |
| 30S ribosomal protein S18 | 0 | 1 | 0 | 1 |
| 30S ribosomal protein S19 | 0 | 1 | 0 | 1 |
| 30S ribosomal protein S20 | 0 | 1 | 0 | 1 |
| 30S ribosomal protein S2 | 0 | 1 | 0 | 1 |
| 30S ribosomal protein S3 | 0 | 1 | 0 | 1 |
| 30S ribosomal protein S4 | 0 | 1 | 0 | 1 |
| 30S ribosomal protein S5 | 0 | 1 | 0 | 1 |
| 30S ribosomal protein S8 | 0 | 1 | 0 | 1 |
| 30S ribosomal protein S9 | 0 | 1 | 0 | 1 |
| 50S ribosomal protein L13 | 0 | 1 | 0 | 1 |
| 50S ribosomal protein L14 | 0 | 1 | 0 | 1 |
| 50S ribosomal protein L16 | 0 | 1 | 0 | 1 |
| 50S ribosomal protein L23 | 0 | 1 | 0 | 1 |
| 30S ribosomal protein S15 | 0 | 1 | 0 | 1 |
| 50S ribosomal protein L17 | 0 | 1 | 0 | 1 |
| 50S ribosomal protein L21 | 0 | 1 | 0 | 1 |
| 50S ribosomal protein L30 | 0 | 1 | 0 | 1 |
| 50S ribosomal protein L6 | 0 | 1 | 0 | 1 |
| 30S ribosomal protein S14 | 0 | 1 | 0 | 1 |
| 30S ribosomal protein S17 | 0 | 1 | 0 | 1 |
| 30S ribosomal protein S1 | 0 | 1 | 0 | 1 |
| 50S ribosomal protein L18 | 0 | 1 | 0 | 1 |
| 50S ribosomal protein L2 | 0 | 1 | 0 | 1 |
| 50S ribosomal protein L3 | 0 | 1 | 0 | 1 |
| 50S ribosomal protein L24 | 0 | 1 | 0 | 1 |
| 50S ribosomal protein L4 | 0 | 1 | 0 | 1 |
| 50S ribosomal protein L22 | 0 | 1 | 0 | 1 |
| 50S ribosomal protein L5 | 0 | 1 | 0 | 1 |
| 30S ribosomal protein S21 | 0 | 1 | 0 | 1 |
| 50S ribosomal protein L25 | 0 | 1 | 0 | 1 |
| 50S ribosomal protein L36 2 | 0 | 1 | 0 | 1 |
| Protein-arginine deiminase type-4 | 0 | 1 | 0 | 1 |
| [prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023] |