Page last updated: 2024-09-28

Bloch-Siemens Syndrome

A genodermatosis occurring mostly in females and characterized by skin changes in three phases - vesiculobullous, verrucous papillomatous, and macular melanodermic. Hyperpigmentation is bizarre and irregular. Sixty percent of patients have abnormalities of eyes, teeth, central nervous system, and skin appendages.

Synonyms(4)

Synonym
Bloch-Sulzberger Syndrome
Bloch-Siemens-Sulzberger Syndrome
Bloch-Siemens Syndrome
Incontinentia Pigmenti

Research Excerpts

Overview

ExcerptReference
"Incontinentia pigmenti is a syndrome characterized by both systemic and oral manifestations."( Atasu, M; Aydin, MY; Ergeneli, S; Kargul, B; Tanboga, I, 2001)
"Incontinentia pigmenti is rare and, therefore, diagnosis is frequently delayed."( Gardiner, J; Kaczala, GW; Messer, MA; Poskitt, KJ; Prendiville, JS; Senger, C, 2008)

Treatment

ExcerptReference
"We describe a female infant with incontinentia pigmenti complicated by severe pulmonary arterial hypertension that was markedly improved by tadalafil administration."( Aso, K; Hokuto, I; Kitazawa, T; Migita, O; Mizuno, M; Tsuzuki, Y; Yamamoto, H, 2020)

Research

Studies (42)

TimeframeStudies, This Condition (%)All Conditions %
pre-199010 (23.81)23.3326
1990's9 (21.43)12.5806
2000's12 (28.57)18.1394
2010's8 (19.05)28.8240
2020's3 (7.14)9.53
DrugIndicatedRelationship StrengthStudiesTrials
dinitrochlorobenzene0low10
salicylic acid0low10
cytosine0low10
anthralin0low10
aspirin0low10
dapsone0low10
phenobarbital0low20
propranolol0low10
prednisolone0low20
prednisone0low20
lysine0low10
colchicine0low10
chlorquinaldol0low10
methylprednisolone0low10
fluorescein0low10
transferrin0low10
clarithromycin0low10
diflucortolone valerate0low10
bosentan anhydrous0low10
tadalafil0low10
methotrexate0low10
cortisone0low10
tacrolimus0low10
clindamycin0low10
isomethyleugenol0low10
isoeugenol0low10
etretinate0low10
stilbamidine0low10
diflucortolone0low10
sodium ethylxanthate0low20
minocycline0low10
transforming growth factor beta0low10
thromboplastin0low10
deoxyguanosine0low10
sildenafil citrate0low10
8-hydroxy-2'-deoxyguanosine0low10
eye0low70

Protein Targets (582)

ProteinPotency MeasurementsInhibition MeasurementsActivation MeasurementsDrugs
Chain A, Avidin0022
Chain A, Avidin0022
Chain B, Avidin0022
Chain E, Purine nucleoside phosphorylase0101
Chain A, HADH2 protein6006
Chain B, HADH2 protein6006
Chain A, ATP-DEPENDENT DNA HELICASE Q13003
Chain A, Ferritin light chain6006
Thymidine kinase 0101
thioredoxin reductase100010
phosphopantetheinyl transferase4004
GLS protein6006
TDP1 protein160016
Smad35005
thyroid stimulating hormone receptor5005
EWS/FLI fusion protein4004
arylsulfatase A2002
euchromatic histone-lysine N-methyltransferase 2110011
activating transcription factor 69009
Histone H2A.x4004
Bloom syndrome protein isoform 15005
hemoglobin subunit beta1001
atrial natriuretic peptide receptor 1 precursor2002
ubiquitin carboxyl-terminal hydrolase 2 isoform a2002
lamin isoform A-delta104004
Solute carrier family 22 member 1 0102
ATP-binding cassette sub-family C member 3016016
Multidrug resistance-associated protein 4016017
Solute carrier family 22 member 60203
Bile salt export pump0707
Bile salt export pump019019
Purine nucleoside phosphorylase0101
Thymidine kinase, cytosolic0103
POU domain, class 2, transcription factor 20001
Cytochrome P450 2C9 0415
Cytochrome P450 2J20404
Disintegrin and metalloproteinase domain-containing protein 172002
Purine nucleoside phosphorylase0011
Solute carrier family 22 member 60103
Thymidine kinase 0101
Solute carrier family 22 member 80103
Canalicular multispecific organic anion transporter 1015015
Thymidine kinase0101
Chain A, MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASE6006
Chain A, TYROSYL-DNA PHOSPHODIESTERASE5005
Chain A, Cruzipain2002
15-lipoxygenase, partial2002
hypoxia-inducible factor 1 alpha subunit9009
RAR-related orphan receptor gamma110011
USP1 protein, partial7007
Microtubule-associated protein tau5005
AR protein210021
aldehyde dehydrogenase 1 family, member A17007
core protein, partial0101
glucocorticoid receptor [Homo sapiens]170017
retinoic acid nuclear receptor alpha variant 1150015
estrogen-related nuclear receptor alpha180018
farnesoid X nuclear receptor8008
pregnane X nuclear receptor160016
estrogen nuclear receptor alpha220022
bromodomain adjacent to zinc finger domain 2B5005
peroxisome proliferator activated receptor gamma130013
nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105), isoform CRA_a5005
vitamin D3 receptor isoform VDRA5005
thyroid hormone receptor beta isoform a4004
microphthalmia-associated transcription factor isoform 90101
importin subunit beta-1 isoform 15005
snurportin-15005
GTP-binding nuclear protein Ran isoform 13003
lethal(3)malignant brain tumor-like protein 1 isoform I1001
DNA polymerase kappa isoform 16006
cytochrome P450 3A4 isoform 15005
histone acetyltransferase KAT2A isoform 15005
DNA dC->dU-editing enzyme APOBEC-3G isoform 10101
Gamma-aminobutyric acid receptor subunit pi5117
Cellular tumor antigen p53120012
Polyunsaturated fatty acid 5-lipoxygenase0101
Gamma-aminobutyric acid receptor subunit beta-15117
Gamma-aminobutyric acid receptor subunit delta5117
Gamma-aminobutyric acid receptor subunit gamma-25117
Gamma-aminobutyric acid receptor subunit alpha-55117
Gamma-aminobutyric acid receptor subunit alpha-35117
Gamma-aminobutyric acid receptor subunit gamma-15117
Gamma-aminobutyric acid receptor subunit alpha-25117
Gamma-aminobutyric acid receptor subunit alpha-45117
Gamma-aminobutyric acid receptor subunit gamma-35117
Gamma-aminobutyric acid receptor subunit alpha-65117
Nuclear receptor ROR-gamma5117
Gamma-aminobutyric acid receptor subunit alpha-15218
Gamma-aminobutyric acid receptor subunit beta-35117
Guanine nucleotide-binding protein G1001
Gamma-aminobutyric acid receptor subunit beta-25117
GABA theta subunit5117
5-lipoxygenase 0101
Gamma-aminobutyric acid receptor subunit epsilon5117
NAD-dependent protein deacylase sirtuin-5, mitochondrial0101
Chain A, Phospholipase A2 isoform 30011
Chain A, 2-oxoglutarate Oxygenase4004
GTP-binding protein (rab7)0011
ras protein, partial0011
interleukin 83003
hypothetical protein, conserved2002
cytochrome P450 family 3 subfamily A polypeptide 4130013
cytochrome P450 2D64004
glucocerebrosidase2002
peroxisome proliferator-activated receptor delta100010
Rac1 protein0011
IDH16006
cell division cycle 42 (GTP binding protein, 25kDa), partial0011
15-hydroxyprostaglandin dehydrogenase [NAD(+)] isoform 13003
DNA polymerase iota isoform a (long)4004
muscarinic acetylcholine receptor M13003
lethal factor (plasmid)3003
Prostaglandin-H2 D-isomerase0101
Prostaglandin G/H synthase 1 0101
Prostaglandin G/H synthase 2 0101
Epidermal growth factor receptor0101
Carbonic anhydrase 10405
Carbonic anhydrase 20416
Fatty acid-binding protein, liver0202
Integrin beta-31102
Myeloperoxidase0202
Prostaglandin G/H synthase 10101
Seed linoleate 13S-lipoxygenase-10101
Integrin alpha-IIb1102
Glutathione hydrolase 1 proenzyme0101
Prostaglandin G/H synthase 10303
Adenosine receptor A10101
Adenosine receptor A2a0101
Substance-P receptor0101
Prostaglandin G/H synthase 20404
Urotensin-2 receptor0101
4-aminobutyrate aminotransferase, mitochondrial0101
Ras-related protein Rab-2A0011
Prostaglandin G/H synthase 20101
Rho-associated protein kinase 20101
Nicotinate phosphoribosyltransferase0202
Solute carrier family 22 member 200303
Solute carrier family 22 member 60303
Sigma non-opioid intracellular receptor 10213
Sigma non-opioid intracellular receptor 10011
GLI family zinc finger 3140014
estrogen receptor 2 (ER beta)100010
progesterone receptor120012
G9009
vitamin D (1,25- dihydroxyvitamin D3) receptor110011
v-jun sarcoma virus 17 oncogene homolog (avian)8008
heat shock protein beta-17007
nuclear factor erythroid 2-related factor 2 isoform 1110011
nuclear receptor ROR-gamma isoform 15005
Nuclear receptor subfamily 1 group I member 20033
Interferon beta110011
HLA class I histocompatibility antigen, B alpha chain 9009
Endothelin receptor type B0101
Endothelin receptor type B0213
Endothelin-1 receptor0314
Endothelin-1 receptor0213
Endothelin receptor type B0011
Deoxyhypusine synthase0101
Sodium/bile acid cotransporter0202
Endothelin-1 receptor0101
Inositol hexakisphosphate kinase 19009
cytochrome P450 2C9, partial9009
Nrf21001
glp-1 receptor, partial2002
apical membrane antigen 1, AMA12002
67.9K protein6006
LAP40011
RPL19A0011
heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)1001
cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a110011
thyroid hormone receptor beta isoform 2130013
peptidyl-prolyl cis-trans isomerase NIMA-interacting 12002
geminin140014
Vpr2002
DNA dC->dU-editing enzyme APOBEC-3F isoform a1001
Glycoprotein hormones alpha chain1001
Botulinum neurotoxin type A 0101
TAR DNA-binding protein 434004
ATPase family AAA domain-containing protein 58008
Ataxin-29009
mitogen-activated protein kinase 12002
urokinase-type plasminogen activator precursor2002
plasminogen precursor2002
urokinase plasminogen activator surface receptor precursor2002
streptokinase A precursor0011
ATP-dependent translocase ABCB10405
Cytochrome P450 3A40415
Potassium voltage-gated channel subfamily H member 20404
Solute carrier organic anion transporter family member 1B30102
Solute carrier organic anion transporter family member 1B10202
Protein-arginine deiminase type-40404
Chain A, Beta-lactamase4004
Luciferase3003
endonuclease IV2002
PAX80001
pregnane X receptor4004
ATAD5 protein, partial3003
Fumarate hydratase1001
PPM1D protein2002
Thrombopoietin1001
nuclear receptor subfamily 1, group I, member 39009
retinoid X nuclear receptor alpha110011
polyprotein1001
aryl hydrocarbon receptor8008
nuclear receptor subfamily 1, group I, member 24004
cytochrome P450 2D6 isoform 11001
nuclear receptor subfamily 0 group B member 10101
cellular tumor antigen p53 isoform a2002
cytochrome P450 2C19 precursor1001
cytochrome P450 2C9 precursor2002
chromobox protein homolog 15005
nuclear factor erythroid 2-related factor 2 isoform 27007
atrial natriuretic peptide receptor 2 precursor1001
flap endonuclease 13003
ras-related protein Rab-9A1001
steroidogenic factor 10101
peripheral myelin protein 225005
muscleblind-like protein 1 isoform 14004
caspase-1 isoform alpha precursor2002
neuropeptide S receptor isoform A1001
Solute carrier family 22 member 30101
Voltage-dependent calcium channel gamma-2 subunit6006
Tubulin alpha-1A chain0213
Tubulin beta chain0213
Plasma kallikrein0001
Tubulin beta-4A chain0225
ATP-dependent translocase ABCB10101
Tubulin beta chain0225
Tubulin alpha-3C chain0225
Serine/threonine-protein kinase pim-10101
Glutamate receptor 26006
ATP-dependent translocase ABCB10101
Histamine H2 receptor2002
Tubulin alpha-1B chain0225
Tubulin alpha-4A chain0225
Tubulin beta-4B chain0225
Vesicular acetylcholine transporter0101
Tubulin beta-3 chain0225
Tubulin beta-2A chain0225
Tubulin polymerization-promoting protein0011
Tubulin beta-8 chain0225
Tubulin beta-2B chain0202
Tubulin alpha-3E chain0225
Tubulin alpha-1A chain0225
Similar to alpha-tubulin isoform 1 0101
Similar to alpha-tubulin isoform 1 0101
CREB-binding protein1001
Tubulin alpha-1C chain0225
Tubulin beta-6 chain0225
Tubulin beta-2B chain0225
Tubulin beta-1 chain0225
ATP-dependent phosphofructokinase4004
dopamine D1 receptor2002
regulator of G-protein signaling 42002
peripheral myelin protein 22 isoform 11001
survival motor neuron protein isoform d4004
M-phase phosphoprotein 83003
Glucocorticoid receptor08215
Sex hormone-binding globulin0011
Glycine receptor subunit alpha-10808
Corticosteroid-binding globulin0202
Glycine receptor subunit beta0808
Glycine receptor subunit alpha-20808
Glycine receptor subunit alpha-30808
Potassium voltage-gated channel subfamily A member 10011
Multidrug and toxin extrusion protein 10101
Deoxycytidine kinase0001
6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase 0101
Dihydrofolate reductase0303
5-hydroxytryptamine receptor 60314
Deoxycytidine kinase0001
AAA family ATPase 0001
Sterol O-acyltransferase 10101
Chain A, JmjC domain-containing histone demethylation protein 3A1001
acetylcholinesterase4004
SMAD family member 23003
SMAD family member 33003
thioredoxin glutathione reductase3003
caspase 7, apoptosis-related cysteine protease1001
caspase-31001
thyroid stimulating hormone receptor2002
parathyroid hormone/parathyroid hormone-related peptide receptor precursor1001
Rap guanine nucleotide exchange factor 31001
Glutathione S-transferase omega-10101
thyrotropin-releasing hormone receptor2002
GALC protein1001
Transient receptor potential cation channel subfamily A member 10011
Tyrosinase0101
Chain A, Ribulose-1,5 bisphosphate carboxylase/oxygenase large subunit N-methyltransferase, chloroplast0101
Chain A, Ribulose-1,5 bisphosphate carboxylase/oxygenase large subunit N-methyltransferase, chloroplast0101
potassium voltage-gated channel subfamily H member 2 isoform d2002
Glutathione reductase, mitochondrial0202
Cationic amino acid transporter 30101
Chain B, DIHYDROFOLATE REDUCTASE0011
Chain B, DIHYDROFOLATE REDUCTASE0011
Chain B, DIHYDROFOLATE REDUCTASE0011
acid sphingomyelinase1001
ClpP1001
Thymidylate synthase 0101
alpha-galactosidase1001
Thymidylate synthase 0101
polyunsaturated fatty acid lipoxygenase ALOX121001
transcriptional regulator ERG isoform 31001
DNA polymerase beta1001
nuclear receptor coactivator 1 isoform 1 [Homo sapiens]0101
DNA polymerase eta isoform 11001
transactivating tegument protein VP16 [Human herpesvirus 1]0101
nuclear receptor coactivator 3 isoform a0101
Toll-like receptor 40101
Fatty-acid amide hydrolase 10101
ATP-binding cassette sub-family C member 30102
Dihydrofolate reductase0203
Dihydrofolate reductase0203
Dihydrofolate reductase 0101
Dihydrofolate reductase0101
Dihydrofolate reductase0101
Dihydrofolate reductase0203
Thymidylate synthase0101
Tyrosine-protein kinase ABL10011
Thymidylate synthase0202
Bifunctional dihydrofolate reductase-thymidylate synthase0101
Thymidylate synthase0202
5-hydroxytryptamine receptor 2C0102
High mobility group protein B10022
Dihydrofolate reductase0101
Thymidylate synthase0101
Dihydrofolate reductase0224
Glucose-6-phosphate 1-dehydrogenase0101
Bifunctional dihydrofolate reductase-thymidylate synthase0101
Folate receptor beta0101
5-hydroxytryptamine receptor 2A0101
Cytochrome P450 11B1, mitochondrial 0101
Folate receptor alpha0101
Histidine decarboxylase0101
Trifunctional purine biosynthetic protein adenosine-30101
Cyclin-dependent kinase 20011
Bifunctional purine biosynthesis protein ATIC0202
Multidrug resistance-associated protein 1 0001
Delta-type opioid receptor0101
Mu-type opioid receptor0101
Kappa-type opioid receptor0101
Reduced folate transporter0202
Folylpolyglutamate synthase, mitochondrial0103
6-phosphogluconate dehydrogenase, decarboxylating0101
Caspase-71001
Spike glycoprotein3003
Solute carrier organic anion transporter family member 1A30001
Dihydrofolate reductase0101
Pteridine reductase 10101
Folylpolyglutamate synthase, mitochondrial0103
Bifunctional dihydrofolate reductase-thymidylate synthase0101
Bifunctional dihydrofolate reductase-thymidylate synthase0101
Canalicular multispecific organic anion transporter 10102
Trifunctional purine biosynthetic protein adenosine-30101
Dihydrofolate reductase 0101
Dihydrofolate reductase0101
ATP-binding cassette sub-family C member 110001
Proton-coupled folate transporter0101
Multidrug resistance associated protein0102
Solute carrier family 22 member 110001
Broad substrate specificity ATP-binding cassette transporter ABCG20102
hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)3003
nonstructural protein 12002
Androgen receptor0303
Nuclear receptor subfamily 1 group I member 20011
Albumin0123
Stromelysin-10112
Matrilysin0101
Multidrug transporter MdfA0101
Matrix metalloproteinase-90101
Protein mono-ADP-ribosyltransferase PARP150101
Sodium channel protein type 1 subunit alpha0101
Sodium channel protein type 2 subunit alpha0101
Sodium channel protein type 3 subunit alpha0101
luciferase0001
Estrogen receptor0202
Progesterone receptor0203
Glucocorticoid receptor0112
Glucocorticoid receptor0011
Mineralocorticoid receptor 0213
Androgen receptor0202
Glutamine synthetase0011
Histamine H1 receptor0011
Nociceptin receptor0011
Estrogen receptor beta0202
Beta-1 adrenergic receptor 0113
D(1A) dopamine receptor1001
Voltage-dependent L-type calcium channel subunit alpha-1C0101
5-hydroxytryptamine receptor 40202
Cytochrome P450 1A20112
Beta-2 adrenergic receptor0213
Muscarinic acetylcholine receptor M20112
Beta-1 adrenergic receptor0213
5-hydroxytryptamine receptor 1A0101
Alpha-2A adrenergic receptor0124
Adenosine receptor A30314
Beta-2 adrenergic receptor0203
Cytochrome P450 2C80101
Cytochrome P450 2D60112
Muscarinic acetylcholine receptor M10112
Beta-3 adrenergic receptor0213
D(2) dopamine receptor0112
Alpha-1B adrenergic receptor0314
Alpha-2B adrenergic receptor0012
Beta-1 adrenergic receptor0214
Alpha-2C adrenergic receptor0124
D(3) dopamine receptor0101
5-hydroxytryptamine receptor 1A0315
Alpha-2B adrenergic receptor0011
Muscarinic acetylcholine receptor M30112
D(1A) dopamine receptor0112
Voltage-dependent L-type calcium channel subunit alpha-1C0101
Alpha-2C adrenergic receptor0011
Alpha-2A adrenergic receptor0011
Alpha-1D adrenergic receptor0213
Alpha-1D adrenergic receptor0012
Beta-3 adrenergic receptor0202
5-hydroxytryptamine receptor 1B0213
5-hydroxytryptamine receptor 2A0213
5-hydroxytryptamine receptor 2C0213
5-hydroxytryptamine receptor 1B0202
Adenosine receptor A2a0112
Neuromedin-K receptor0011
Type-1 angiotensin II receptor0112
Sodium-dependent serotonin transporter0202
Cholecystokinin receptor type A0112
Cytochrome P450 2C190112
5-hydroxytryptamine receptor 70112
Beta-1 adrenergic receptor0101
Alpha-1A adrenergic receptor0124
Alpha-1B adrenergic receptor0012
Mu-type opioid receptor0112
Vasopressin V1a receptor0112
Delta-type opioid receptor0112
Kappa-type opioid receptor0112
5-hydroxytryptamine receptor 2B0415
Alpha-1A adrenergic receptor0314
5-hydroxytryptamine receptor 70101
Beta-2 adrenergic receptor0101
Voltage-dependent L-type calcium channel subunit alpha-1C0202
Sodium channel protein type 5 subunit alpha0202
Beta-2 adrenergic receptor0113
Nuclear receptor subfamily 2 group E member 10033
chaperonin-containing TCP-1 beta subunit homolog1001
Estrogen receptor beta0001
Inhibitor of nuclear factor kappa-B kinase subunit beta0001
Polyphenol oxidase 20102
Carbonic anhydrase 120102
5'-AMP-activated protein kinase subunit beta-20001
Polymerase acidic protein0011
Carbonic anhydrase 30102
Tyrosine-protein phosphatase YopH0101
Aldo-keto reductase family 1 member B10101
Prolyl 4-hydroxylase subunit alpha-10101
Tyrosine-protein phosphatase non-receptor type 10103
Estrogen receptor0001
Acetylcholinesterase0101
Carbonic anhydrase 40102
Carbonic anhydrase 60102
Cystathionine gamma-lyase0101
Carbonic anhydrase 5A, mitochondrial0102
Carbonic anhydrase 70102
5'-AMP-activated protein kinase subunit gamma-10001
5'-AMP-activated protein kinase catalytic subunit alpha-20001
Xanthine dehydrogenase/oxidase0101
5'-AMP-activated protein kinase catalytic subunit alpha-10001
Carbonic anhydrase 90102
Carbonic anhydrase0101
Solute carrier family 22 member 70001
Ubiquitin-like domain-containing CTD phosphatase 10101
Carbonic anhydrase 150101
Carbonic anhydrase 130102
5'-AMP-activated protein kinase subunit gamma-30001
5'-AMP-activated protein kinase subunit gamma-20001
Carbonic anhydrase 140102
Carbonic anhydrase 5B, mitochondrial0102
5'-AMP-activated protein kinase subunit beta-10001
cGMP-specific 3',5'-cyclic phosphodiesterase0314
Caspase-72002
caspase-32002
Protein arginine N-methyltransferase 50101
RmtA0101
Histone-arginine methyltransferase CARM10101
Protein arginine N-methyltransferase 60101
Protein arginine N-methyltransferase 10202
UDP-glucuronosyltransferase 2B70001
Cytochrome P450 3A50101
UDP-glucuronosyltransferase 1A40001
Serine/threonine-protein kinase mTOR0101
Peptidyl-prolyl cis-trans isomerase FKBP1A0213
Peptidyl-prolyl cis-trans isomerase FKBP1B0011
Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform0101
Peptidyl-prolyl cis-trans isomerase FKBP50101
Splicing factor 3B subunit 30101
Chain A, cAMP-specific 3',5'-cyclic phosphodiesterase 4B0101
Chain A, cAMP-specific 3',5'-cyclic phosphodiesterase 4B0101
Chain A, cAMP-specific 3',5'-cyclic phosphodiesterase 4B0101
Chain A, cAMP-specific 3',5'-cyclic phosphodiesterase 4B0101
Chain A, cAMP-specific 3',5'-cyclic phosphodiesterase 4B0101
Chain A, cAMP-specific 3',5'-cyclic phosphodiesterase 4B0101
Chain A, cAMP-specific 3',5'-cyclic phosphodiesterase 4D0101
Chain A, cAMP-specific 3',5'-cyclic phosphodiesterase 4D0101
Chain A, cAMP-specific 3',5'-cyclic phosphodiesterase 4D0101
Chain A, cAMP-specific 3',5'-cyclic phosphodiesterase 4D0101
Chain A, cAMP-specific 3',5'-cyclic phosphodiesterase 4B0101
Chain B, cAMP-specific 3',5'-cyclic phosphodiesterase 4B0101
Chain A, cGMP-specific 3',5'-cyclic phosphodiesterase0101
Chain A, cGMP-specific 3',5'-cyclic phosphodiesterase0101
Phosphodiesterase 0101
cGMP-dependent 3',5'-cyclic phosphodiesterase0101
Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta0101
cGMP-specific 3',5'-cyclic phosphodiesterase0112
High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8A0101
High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A0101
High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8B0101
Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gamma0101
Rod cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha0101
Cystic fibrosis transmembrane conductance regulator0011
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A 0101
Potassium voltage-gated channel subfamily E member 10101
Rod cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha0101
Cone cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha'0101
Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gamma0101
Retinal cone rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gamma0101
Rod cGMP-specific 3',5'-cyclic phosphodiesterase subunit beta0101
cAMP-specific 3',5'-cyclic phosphodiesterase 4A0101
Rod cGMP-specific 3',5'-cyclic phosphodiesterase subunit beta0101
Acetylcholinesterase0101
Cone cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha'0101
Potassium voltage-gated channel subfamily KQT member 10101
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A0101
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B0101
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B0101
Synaptic vesicular amine transporter0101
cAMP-specific 3',5'-cyclic phosphodiesterase 4B0101
cAMP-specific 3',5'-cyclic phosphodiesterase 4C0101
cAMP-specific 3',5'-cyclic phosphodiesterase 4D0101
cGMP-inhibited 3',5'-cyclic phosphodiesterase B0101
High affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A0101
Retinal cone rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gamma0101
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C0101
cGMP-inhibited 3',5'-cyclic phosphodiesterase A0101
cGMP-specific 3',5'-cyclic phosphodiesterase0101
Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta0101
Dual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A0101
cAMP-specific 3',5'-cyclic phosphodiesterase 7B0101
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A0101
Chain A, Nuclear Receptor ROR-beta0101
Parkin1001
Ornithine decarboxylase0001
Amyloid-beta precursor protein0101
Ornithine decarboxylase0001
60 kDa chaperonin0101
Retinoic acid receptor alpha0227
60 kDa heat shock protein, mitochondrial0101
Retinoic acid receptor beta0227
Retinoic acid receptor alpha0123
Retinoic acid receptor gamma 0227
Alpha-1A adrenergic receptor0101
Retinoic acid receptor gamma0123
Retinoic acid receptor RXR-alpha0224
Retinoic acid receptor beta0123
Cellular retinoic acid-binding protein 20011
Mitogen-activated protein kinase 10101
Retinoic acid receptor RXR-alpha0123
Retinoic acid receptor RXR-beta0224
Retinoic acid receptor RXR-beta0123
Retinoic acid receptor RXR-gamma0123
Indoleamine 2,3-dioxygenase 10101
Nuclear receptor ROR-alpha0101
Alpha-synuclein0101
Cellular retinoic acid-binding protein 10102
Retinoic acid receptor RXR-gamma0224
10 kDa heat shock protein, mitochondrial0101
Cellular retinoic acid-binding protein 10011
Peptidyl-prolyl cis-trans isomerase NIMA-interacting 10213
Thiosulfate sulfurtransferase0101
60 kDa chaperonin 0101
10 kDa chaperonin 0101
Indoleamine 2,3-dioxygenase 20101
Nuclear receptor ROR-beta0101
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]