| Protein | Potency Measurements | Inhibition Measurements | Activation Measurements | Drugs |
|---|
| Chain A, TYROSYL-DNA PHOSPHODIESTERASE | 1 | 0 | 0 | 1 |
| Chain A, HADH2 protein | 1 | 0 | 0 | 1 |
| Chain B, HADH2 protein | 1 | 0 | 0 | 1 |
| Chain A, JmjC domain-containing histone demethylation protein 3A | 1 | 0 | 0 | 1 |
| 5-hydroxytryptamine receptor 3E | 0 | 1 | 0 | 1 |
| Luciferase | 1 | 0 | 0 | 1 |
| acetylcholinesterase | 1 | 0 | 0 | 1 |
| thioredoxin reductase | 1 | 0 | 0 | 1 |
| hypoxia-inducible factor 1 alpha subunit | 1 | 0 | 0 | 1 |
| RAR-related orphan receptor gamma | 1 | 0 | 0 | 1 |
| ATAD5 protein, partial | 1 | 0 | 0 | 1 |
| Fumarate hydratase | 1 | 0 | 0 | 1 |
| NFKB1 protein, partial | 1 | 0 | 0 | 1 |
| GLS protein | 1 | 0 | 0 | 1 |
| TDP1 protein | 1 | 0 | 0 | 1 |
| GLI family zinc finger 3 | 1 | 0 | 0 | 1 |
| Microtubule-associated protein tau | 1 | 0 | 0 | 1 |
| AR protein | 1 | 0 | 0 | 1 |
| caspase 7, apoptosis-related cysteine protease | 1 | 0 | 0 | 1 |
| thyroid stimulating hormone receptor | 1 | 0 | 0 | 1 |
| estrogen receptor 2 (ER beta) | 1 | 0 | 0 | 1 |
| nuclear receptor subfamily 1, group I, member 3 | 1 | 0 | 0 | 1 |
| progesterone receptor | 1 | 0 | 0 | 1 |
| cytochrome P450 family 3 subfamily A polypeptide 4 | 1 | 0 | 0 | 1 |
| EWS/FLI fusion protein | 1 | 0 | 0 | 1 |
| glucocorticoid receptor [Homo sapiens] | 1 | 0 | 0 | 1 |
| retinoic acid nuclear receptor alpha variant 1 | 1 | 0 | 0 | 1 |
| estrogen-related nuclear receptor alpha | 1 | 0 | 0 | 1 |
| estrogen nuclear receptor alpha | 1 | 0 | 0 | 1 |
| G | 1 | 0 | 0 | 1 |
| cytochrome P450 2D6 | 1 | 0 | 0 | 1 |
| polyprotein | 1 | 0 | 0 | 1 |
| Beta-1 adrenergic receptor | 0 | 1 | 0 | 1 |
| glucocerebrosidase | 1 | 0 | 0 | 1 |
| bromodomain adjacent to zinc finger domain 2B | 1 | 0 | 0 | 1 |
| peroxisome proliferator-activated receptor delta | 1 | 0 | 0 | 1 |
| vitamin D (1,25- dihydroxyvitamin D3) receptor | 1 | 0 | 0 | 1 |
| caspase-3 | 1 | 0 | 0 | 1 |
| IDH1 | 1 | 0 | 0 | 1 |
| Adenylate cyclase type 1 | 0 | 1 | 0 | 1 |
| Histone H2A.x | 1 | 0 | 0 | 1 |
| Bloom syndrome protein isoform 1 | 1 | 0 | 0 | 1 |
| cytochrome P450 2D6 isoform 1 | 1 | 0 | 0 | 1 |
| peripheral myelin protein 22 isoform 1 | 1 | 0 | 0 | 1 |
| cytochrome P450 2C19 precursor | 1 | 0 | 0 | 1 |
| cytochrome P450 2C9 precursor | 1 | 0 | 0 | 1 |
| D(1A) dopamine receptor | 1 | 0 | 0 | 1 |
| chromobox protein homolog 1 | 1 | 0 | 0 | 1 |
| potassium voltage-gated channel subfamily H member 2 isoform d | 1 | 0 | 0 | 1 |
| thyroid hormone receptor beta isoform 2 | 1 | 0 | 0 | 1 |
| DNA polymerase beta | 1 | 0 | 0 | 1 |
| mitogen-activated protein kinase 1 | 1 | 0 | 0 | 1 |
| atrial natriuretic peptide receptor 2 precursor | 1 | 0 | 0 | 1 |
| nuclear factor erythroid 2-related factor 2 isoform 1 | 1 | 0 | 0 | 1 |
| DNA polymerase iota isoform a (long) | 1 | 0 | 0 | 1 |
| nuclear receptor ROR-gamma isoform 1 | 1 | 0 | 0 | 1 |
| short transient receptor potential channel 6 isoform 1 | 0 | 0 | 1 | 1 |
| peripheral myelin protein 22 | 1 | 0 | 0 | 1 |
| survival motor neuron protein isoform d | 1 | 0 | 0 | 1 |
| cytochrome P450 3A4 isoform 1 | 1 | 0 | 0 | 1 |
| M-phase phosphoprotein 8 | 1 | 0 | 0 | 1 |
| transient receptor potential cation channel subfamily V member 1 | 1 | 0 | 0 | 1 |
| muscarinic acetylcholine receptor M1 | 1 | 0 | 0 | 1 |
| lethal factor (plasmid) | 1 | 0 | 0 | 1 |
| lamin isoform A-delta10 | 1 | 0 | 0 | 1 |
| Gamma-aminobutyric acid receptor subunit pi | 1 | 1 | 0 | 2 |
| Polyunsaturated fatty acid lipoxygenase ALOX15B | 1 | 0 | 0 | 1 |
| ATP-binding cassette sub-family C member 3 | 0 | 1 | 0 | 1 |
| Multidrug resistance-associated protein 4 | 0 | 1 | 0 | 1 |
| Voltage-dependent L-type calcium channel subunit alpha-1F | 0 | 1 | 0 | 1 |
| Bile salt export pump | 0 | 1 | 0 | 1 |
| 5-hydroxytryptamine receptor 3A | 0 | 1 | 0 | 1 |
| 5-hydroxytryptamine receptor 4 | 0 | 2 | 0 | 2 |
| Voltage-dependent calcium channel gamma-2 subunit | 1 | 0 | 0 | 1 |
| 5-hydroxytryptamine receptor 3B | 0 | 1 | 0 | 1 |
| Bile salt export pump | 0 | 1 | 0 | 1 |
| Interferon beta | 1 | 0 | 0 | 1 |
| HLA class I histocompatibility antigen, B alpha chain | 1 | 0 | 0 | 1 |
| Albumin | 0 | 0 | 1 | 1 |
| Aldo-keto reductase family 1 member B1 | 0 | 2 | 0 | 2 |
| Muscarinic acetylcholine receptor M2 | 0 | 2 | 1 | 3 |
| Muscarinic acetylcholine receptor M4 | 0 | 2 | 1 | 3 |
| ATP-dependent translocase ABCB1 | 0 | 0 | 0 | 1 |
| Muscarinic acetylcholine receptor M1 | 0 | 2 | 0 | 2 |
| Muscarinic acetylcholine receptor M3 | 0 | 2 | 0 | 2 |
| Muscarinic acetylcholine receptor M4 | 0 | 2 | 0 | 2 |
| Cytochrome P450 3A4 | 0 | 1 | 0 | 2 |
| 5-hydroxytryptamine receptor 1A | 0 | 2 | 0 | 2 |
| 5-hydroxytryptamine receptor 2C | 0 | 2 | 0 | 2 |
| Muscarinic acetylcholine receptor M5 | 0 | 2 | 0 | 2 |
| Muscarinic acetylcholine receptor M5 | 0 | 2 | 0 | 2 |
| Alpha-2A adrenergic receptor | 0 | 2 | 0 | 2 |
| Calmodulin-1 | 0 | 1 | 0 | 1 |
| Beta-2 adrenergic receptor | 0 | 2 | 0 | 2 |
| Cytochrome P450 2D6 | 0 | 0 | 0 | 1 |
| Muscarinic acetylcholine receptor M2 | 0 | 2 | 0 | 2 |
| Muscarinic acetylcholine receptor M1 | 0 | 2 | 1 | 3 |
| Cytochrome P450 2C9 | 0 | 1 | 0 | 2 |
| Angiotensin-converting enzyme | 0 | 2 | 0 | 2 |
| D(2) dopamine receptor | 0 | 2 | 0 | 5 |
| 5-hydroxytryptamine receptor 2A | 0 | 2 | 0 | 2 |
| Gamma-aminobutyric acid receptor subunit beta-1 | 1 | 1 | 0 | 2 |
| Alpha-1B adrenergic receptor | 0 | 2 | 1 | 3 |
| Alpha-2B adrenergic receptor | 0 | 2 | 0 | 2 |
| Beta-1 adrenergic receptor | 0 | 1 | 0 | 1 |
| Gamma-aminobutyric acid receptor subunit delta | 1 | 1 | 0 | 2 |
| Gamma-aminobutyric acid receptor subunit gamma-2 | 1 | 1 | 0 | 2 |
| Alpha-2C adrenergic receptor | 0 | 2 | 0 | 2 |
| D | 0 | 2 | 0 | 2 |
| D(3) dopamine receptor | 0 | 2 | 0 | 2 |
| 5-hydroxytryptamine receptor 1A | 0 | 2 | 0 | 2 |
| Alpha-2B adrenergic receptor | 0 | 2 | 1 | 3 |
| Glutamate receptor 2 | 1 | 0 | 0 | 1 |
| Gamma-aminobutyric acid receptor subunit alpha-5 | 1 | 1 | 0 | 2 |
| Gamma-aminobutyric acid receptor subunit alpha-3 | 1 | 1 | 0 | 2 |
| D(2) dopamine receptor | 0 | 2 | 0 | 2 |
| Muscarinic acetylcholine receptor M3 | 0 | 2 | 1 | 3 |
| Endothelin receptor type B | 0 | 1 | 0 | 1 |
| D(1A) dopamine receptor | 0 | 2 | 0 | 3 |
| D(4) dopamine receptor | 0 | 2 | 0 | 4 |
| D(1B) dopamine receptor | 0 | 1 | 0 | 2 |
| Adenylate cyclase type 3 | 0 | 1 | 0 | 1 |
| Alpha-2C adrenergic receptor | 0 | 2 | 1 | 3 |
| UDP-glucuronosyltransferase 1A4 | 0 | 0 | 0 | 1 |
| Alpha-2A adrenergic receptor | 0 | 2 | 1 | 3 |
| Gamma-aminobutyric acid receptor subunit gamma-1 | 1 | 1 | 0 | 2 |
| Gamma-aminobutyric acid receptor subunit alpha-2 | 1 | 1 | 0 | 2 |
| Alpha-1D adrenergic receptor | 0 | 2 | 1 | 3 |
| Sodium-dependent noradrenaline transporter | 0 | 2 | 0 | 2 |
| Sodium-dependent dopamine transporter | 0 | 2 | 0 | 2 |
| 5-hydroxytryptamine receptor 3A | 0 | 1 | 0 | 1 |
| Endothelin receptor type B | 0 | 1 | 0 | 1 |
| Histamine H2 receptor | 0 | 2 | 0 | 2 |
| Adenosine receptor A1 | 0 | 1 | 0 | 1 |
| Alpha-1D adrenergic receptor | 0 | 2 | 0 | 2 |
| D(1B) dopamine receptor | 0 | 2 | 0 | 2 |
| Beta-3 adrenergic receptor | 0 | 1 | 0 | 1 |
| Adenylate cyclase type 2 | 0 | 1 | 0 | 1 |
| Adenylate cyclase type 4 | 0 | 1 | 0 | 1 |
| 5-hydroxytryptamine receptor 2A | 0 | 2 | 0 | 4 |
| 5-hydroxytryptamine receptor 2C | 0 | 2 | 1 | 3 |
| Gamma-aminobutyric acid receptor subunit alpha-4 | 1 | 1 | 0 | 2 |
| Gamma-aminobutyric acid receptor subunit gamma-3 | 1 | 1 | 0 | 2 |
| 5-hydroxytryptamine receptor 1B | 0 | 2 | 0 | 2 |
| 5-hydroxytryptamine receptor 1D | 0 | 2 | 0 | 2 |
| Gamma-aminobutyric acid receptor subunit alpha-6 | 1 | 1 | 0 | 2 |
| D(4) dopamine receptor | 0 | 2 | 0 | 2 |
| 5-hydroxytryptamine receptor 1F | 0 | 2 | 0 | 2 |
| 5-hydroxytryptamine receptor 2B | 0 | 2 | 1 | 3 |
| Histamine H1 receptor | 0 | 1 | 0 | 1 |
| Histamine H1 receptor | 0 | 2 | 0 | 2 |
| Sodium-dependent serotonin transporter | 0 | 2 | 0 | 2 |
| Sodium-dependent serotonin transporter | 0 | 1 | 0 | 1 |
| 5-hydroxytryptamine receptor 7 | 0 | 1 | 0 | 1 |
| Cytochrome P450 2C19 | 0 | 0 | 0 | 1 |
| 5-hydroxytryptamine receptor 2C | 0 | 1 | 0 | 1 |
| 5-hydroxytryptamine receptor 7 | 0 | 1 | 0 | 1 |
| Alpha-1A adrenergic receptor | 0 | 1 | 0 | 1 |
| 5-hydroxytryptamine receptor 2A | 0 | 1 | 0 | 1 |
| Histamine H1 receptor | 0 | 2 | 2 | 6 |
| Alpha-1B adrenergic receptor | 0 | 1 | 0 | 1 |
| D(3) dopamine receptor | 0 | 2 | 0 | 4 |
| 5-hydroxytryptamine receptor 3A | 0 | 1 | 0 | 1 |
| Adenylate cyclase type 8 | 0 | 1 | 0 | 1 |
| 5-hydroxytryptamine receptor 2B | 0 | 2 | 1 | 3 |
| Alpha-1A adrenergic receptor | 0 | 2 | 1 | 3 |
| 5-hydroxytryptamine receptor 3A | 0 | 1 | 0 | 1 |
| Histamine H2 receptor | 1 | 0 | 0 | 1 |
| 5-hydroxytryptamine receptor 5A | 0 | 1 | 0 | 1 |
| 5-hydroxytryptamine receptor 6 | 0 | 2 | 0 | 3 |
| Cytochrome P450 2J2 | 0 | 1 | 0 | 2 |
| 3-hydroxy-3-methylglutaryl-coenzyme A reductase | 0 | 1 | 0 | 1 |
| D(2) dopamine receptor | 0 | 1 | 0 | 1 |
| D(3) dopamine receptor | 0 | 1 | 0 | 1 |
| Gastrin/cholecystokinin type B receptor | 0 | 1 | 0 | 1 |
| Spike glycoprotein | 1 | 0 | 0 | 1 |
| D(2) dopamine receptor | 0 | 1 | 0 | 1 |
| D(2) dopamine receptor | 0 | 2 | 0 | 2 |
| Calmodulin | 0 | 0 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit alpha-1 | 1 | 1 | 0 | 2 |
| Gamma-aminobutyric acid receptor subunit beta-3 | 1 | 1 | 0 | 2 |
| Gamma-aminobutyric acid receptor subunit beta-2 | 1 | 1 | 0 | 2 |
| Inositol monophosphatase 1 | 1 | 0 | 0 | 1 |
| Voltage-dependent L-type calcium channel subunit alpha-1D | 0 | 1 | 0 | 1 |
| Sodium-dependent dopamine transporter | 0 | 1 | 0 | 1 |
| 5-hydroxytryptamine receptor 2B | 0 | 1 | 0 | 1 |
| Adenylate cyclase type 6 | 0 | 1 | 0 | 1 |
| Adenylate cyclase type 5 | 0 | 1 | 0 | 1 |
| Potassium voltage-gated channel subfamily H member 2 | 0 | 2 | 0 | 2 |
| 5-hydroxytryptamine receptor 4 | 0 | 1 | 0 | 1 |
| Voltage-dependent L-type calcium channel subunit alpha-1S | 0 | 1 | 0 | 1 |
| Voltage-dependent L-type calcium channel subunit alpha-1C | 0 | 1 | 0 | 1 |
| Transporter | 0 | 1 | 0 | 1 |
| Cholecystokinin receptor type A | 0 | 1 | 0 | 1 |
| 5-hydroxytryptamine receptor 1A | 0 | 1 | 0 | 1 |
| Nuclear receptor subfamily 3 group C member 3 | 0 | 2 | 0 | 2 |
| 5-hydroxytryptamine receptor 3D | 0 | 1 | 0 | 1 |
| Adenylyl cyclase 7 | 0 | 1 | 0 | 1 |
| 5-hydroxytryptamine receptor 3C | 0 | 1 | 0 | 1 |
| GABA theta subunit | 1 | 1 | 0 | 2 |
| Inositol hexakisphosphate kinase 1 | 1 | 0 | 0 | 1 |
| Canalicular multispecific organic anion transporter 1 | 0 | 1 | 0 | 1 |
| D | 0 | 2 | 0 | 2 |
| ATPase family AAA domain-containing protein 5 | 1 | 0 | 0 | 1 |
| Ataxin-2 | 1 | 0 | 0 | 1 |
| Sigma non-opioid intracellular receptor 1 | 0 | 1 | 0 | 1 |
| Gamma-aminobutyric acid receptor subunit epsilon | 1 | 1 | 0 | 2 |
| Histamine H4 receptor | 0 | 1 | 1 | 2 |
| 5-hydroxytryptamine receptor 3B | 0 | 1 | 0 | 1 |
| Sigma non-opioid intracellular receptor 1 | 0 | 1 | 0 | 1 |
| Transporter | 0 | 1 | 0 | 1 |
| Histamine H3 receptor | 0 | 1 | 0 | 1 |
| cytochrome P450 2C9, partial | 1 | 0 | 0 | 1 |
| [prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023] |