| Protein | Potency Measurements | Inhibition Measurements | Activation Measurements | Drugs |
|---|
| Chain A, TYROSYL-DNA PHOSPHODIESTERASE | 1 | 0 | 0 | 1 |
| acetylcholinesterase | 1 | 0 | 0 | 1 |
| phosphopantetheinyl transferase | 1 | 0 | 0 | 1 |
| hypoxia-inducible factor 1 alpha subunit | 2 | 0 | 0 | 2 |
| RAR-related orphan receptor gamma | 1 | 0 | 0 | 1 |
| SMAD family member 2 | 1 | 0 | 0 | 1 |
| ATAD5 protein, partial | 1 | 0 | 0 | 1 |
| Fumarate hydratase | 1 | 0 | 0 | 1 |
| USP1 protein, partial | 1 | 0 | 0 | 1 |
| NFKB1 protein, partial | 1 | 0 | 0 | 1 |
| PPM1D protein | 1 | 0 | 0 | 1 |
| SMAD family member 3 | 1 | 0 | 0 | 1 |
| TDP1 protein | 2 | 0 | 0 | 2 |
| Thrombopoietin | 1 | 0 | 0 | 1 |
| AR protein | 2 | 0 | 0 | 2 |
| caspase 7, apoptosis-related cysteine protease | 1 | 0 | 0 | 1 |
| aldehyde dehydrogenase 1 family, member A1 | 1 | 0 | 0 | 1 |
| hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 1 | 0 | 0 | 1 |
| thyroid stimulating hormone receptor | 1 | 0 | 0 | 1 |
| estrogen receptor 2 (ER beta) | 1 | 0 | 0 | 1 |
| nuclear receptor subfamily 1, group I, member 3 | 1 | 0 | 0 | 1 |
| progesterone receptor | 2 | 0 | 0 | 2 |
| EWS/FLI fusion protein | 2 | 0 | 0 | 2 |
| glucocorticoid receptor [Homo sapiens] | 1 | 0 | 0 | 1 |
| retinoic acid nuclear receptor alpha variant 1 | 1 | 0 | 0 | 1 |
| retinoid X nuclear receptor alpha | 1 | 0 | 0 | 1 |
| estrogen-related nuclear receptor alpha | 2 | 0 | 0 | 2 |
| farnesoid X nuclear receptor | 1 | 0 | 0 | 1 |
| pregnane X nuclear receptor | 2 | 0 | 0 | 2 |
| estrogen nuclear receptor alpha | 3 | 0 | 0 | 3 |
| G | 1 | 0 | 0 | 1 |
| cytochrome P450 2D6 | 2 | 0 | 0 | 2 |
| polyprotein | 1 | 0 | 0 | 1 |
| peroxisome proliferator-activated receptor delta | 1 | 0 | 0 | 1 |
| peroxisome proliferator activated receptor gamma | 2 | 0 | 0 | 2 |
| caspase-3 | 1 | 0 | 0 | 1 |
| euchromatic histone-lysine N-methyltransferase 2 | 1 | 0 | 0 | 1 |
| thyroid stimulating hormone receptor | 1 | 0 | 0 | 1 |
| v-jun sarcoma virus 17 oncogene homolog (avian) | 1 | 0 | 0 | 1 |
| Histone H2A.x | 2 | 0 | 0 | 2 |
| cytochrome P450 2D6 isoform 1 | 1 | 0 | 0 | 1 |
| cellular tumor antigen p53 isoform a | 1 | 0 | 0 | 1 |
| cytochrome P450 2C9 precursor | 1 | 0 | 0 | 1 |
| D(1A) dopamine receptor | 1 | 0 | 0 | 1 |
| chromobox protein homolog 1 | 1 | 0 | 0 | 1 |
| thyroid hormone receptor beta isoform a | 1 | 0 | 0 | 1 |
| potassium voltage-gated channel subfamily H member 2 isoform d | 2 | 0 | 0 | 2 |
| thyroid hormone receptor beta isoform 2 | 2 | 0 | 0 | 2 |
| heat shock protein beta-1 | 1 | 0 | 0 | 1 |
| huntingtin isoform 2 | 1 | 0 | 0 | 1 |
| mitogen-activated protein kinase 1 | 1 | 0 | 0 | 1 |
| flap endonuclease 1 | 1 | 0 | 0 | 1 |
| serine/threonine-protein kinase mTOR isoform 1 | 1 | 0 | 0 | 1 |
| nuclear factor erythroid 2-related factor 2 isoform 1 | 2 | 0 | 0 | 2 |
| peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 | 1 | 0 | 0 | 1 |
| urokinase-type plasminogen activator precursor | 1 | 0 | 0 | 1 |
| plasminogen precursor | 1 | 0 | 0 | 1 |
| urokinase plasminogen activator surface receptor precursor | 1 | 0 | 0 | 1 |
| nuclear receptor ROR-gamma isoform 1 | 1 | 0 | 0 | 1 |
| geminin | 1 | 0 | 0 | 1 |
| peripheral myelin protein 22 | 1 | 0 | 0 | 1 |
| survival motor neuron protein isoform d | 1 | 0 | 0 | 1 |
| cytochrome P450 3A4 isoform 1 | 1 | 0 | 0 | 1 |
| muscarinic acetylcholine receptor M1 | 1 | 0 | 0 | 1 |
| lethal factor (plasmid) | 1 | 0 | 0 | 1 |
| lamin isoform A-delta10 | 2 | 0 | 0 | 2 |
| Gamma-aminobutyric acid receptor subunit pi | 1 | 0 | 0 | 1 |
| Polyunsaturated fatty acid lipoxygenase ALOX15B | 1 | 0 | 0 | 1 |
| ATP-binding cassette sub-family C member 3 | 0 | 1 | 0 | 1 |
| Multidrug resistance-associated protein 4 | 0 | 1 | 0 | 1 |
| Voltage-dependent L-type calcium channel subunit alpha-1C | 0 | 1 | 0 | 1 |
| Solute carrier organic anion transporter family member 1A4 | 0 | 1 | 0 | 1 |
| Voltage-dependent L-type calcium channel subunit alpha-1F | 0 | 2 | 0 | 2 |
| 5-hydroxytryptamine receptor 4 | 0 | 2 | 0 | 2 |
| Lysine-specific demethylase PHF2 | 0 | 1 | 0 | 1 |
| Bile salt export pump | 0 | 2 | 0 | 2 |
| Interferon beta | 1 | 0 | 0 | 1 |
| HLA class I histocompatibility antigen, B alpha chain | 1 | 0 | 0 | 1 |
| Thyroid hormone receptor alpha | 0 | 1 | 0 | 1 |
| Receptor tyrosine-protein kinase erbB-2 | 0 | 1 | 0 | 1 |
| Cellular tumor antigen p53 | 1 | 0 | 0 | 1 |
| Integrin beta-3 | 1 | 0 | 0 | 1 |
| Tyrosine-protein kinase Fyn | 0 | 1 | 0 | 1 |
| ATP-dependent translocase ABCB1 | 0 | 1 | 0 | 1 |
| Aldo-keto reductase family 1 member B1 | 0 | 2 | 0 | 2 |
| Muscarinic acetylcholine receptor M2 | 0 | 2 | 0 | 2 |
| Muscarinic acetylcholine receptor M4 | 0 | 2 | 0 | 2 |
| ATP-dependent translocase ABCB1 | 0 | 2 | 1 | 3 |
| Integrin alpha-IIb | 1 | 0 | 0 | 1 |
| Beta-1 adrenergic receptor | 0 | 2 | 0 | 2 |
| Muscarinic acetylcholine receptor M5 | 0 | 2 | 0 | 2 |
| Alpha-2A adrenergic receptor | 0 | 2 | 0 | 2 |
| Adenosine receptor A3 | 0 | 2 | 0 | 2 |
| Cytochrome P450 2C8 | 0 | 1 | 0 | 1 |
| Thyroid hormone receptor alpha | 0 | 1 | 0 | 1 |
| Thyroid hormone receptor beta | 0 | 1 | 0 | 1 |
| Muscarinic acetylcholine receptor M1 | 0 | 2 | 0 | 2 |
| Beta-3 adrenergic receptor | 0 | 2 | 0 | 2 |
| D(2) dopamine receptor | 0 | 2 | 0 | 2 |
| Androgen receptor | 0 | 2 | 0 | 2 |
| Gamma-aminobutyric acid receptor subunit beta-1 | 1 | 0 | 0 | 1 |
| Alpha-1B adrenergic receptor | 0 | 2 | 0 | 2 |
| Lethal factor | 0 | 1 | 0 | 1 |
| Alpha-2B adrenergic receptor | 0 | 2 | 0 | 2 |
| Thyroid hormone receptor beta | 0 | 1 | 0 | 1 |
| Gamma-aminobutyric acid receptor subunit delta | 1 | 0 | 0 | 1 |
| Gamma-aminobutyric acid receptor subunit gamma-2 | 1 | 0 | 0 | 1 |
| Gamma-aminobutyric acid receptor subunit alpha-5 | 1 | 0 | 0 | 1 |
| Gamma-aminobutyric acid receptor subunit alpha-3 | 1 | 0 | 0 | 1 |
| Muscarinic acetylcholine receptor M3 | 0 | 2 | 0 | 2 |
| ATP-dependent translocase ABCB1 | 0 | 1 | 0 | 1 |
| Substance-K receptor | 0 | 2 | 0 | 2 |
| D(1A) dopamine receptor | 0 | 2 | 0 | 2 |
| D(4) dopamine receptor | 0 | 2 | 0 | 2 |
| Gamma-aminobutyric acid receptor subunit gamma-1 | 1 | 0 | 0 | 1 |
| Gamma-aminobutyric acid receptor subunit alpha-2 | 1 | 0 | 0 | 1 |
| Carnitine O-palmitoyltransferase 2, mitochondrial | 0 | 1 | 0 | 1 |
| Sodium-dependent noradrenaline transporter | 0 | 2 | 0 | 2 |
| Histamine H2 receptor | 0 | 2 | 0 | 2 |
| Endothelin-1 receptor | 0 | 2 | 0 | 2 |
| 5-hydroxytryptamine receptor 2A | 0 | 2 | 0 | 2 |
| 5-hydroxytryptamine receptor 2C | 0 | 2 | 0 | 2 |
| Gamma-aminobutyric acid receptor subunit alpha-4 | 1 | 0 | 0 | 1 |
| Gamma-aminobutyric acid receptor subunit gamma-3 | 1 | 0 | 0 | 1 |
| Lysine-specific demethylase 5A | 0 | 1 | 0 | 1 |
| Gamma-aminobutyric acid receptor subunit alpha-6 | 1 | 0 | 0 | 1 |
| B2 bradykinin receptor | 0 | 2 | 0 | 2 |
| Sodium-dependent serotonin transporter | 0 | 2 | 0 | 2 |
| Melanocortin receptor 4 | 0 | 2 | 0 | 2 |
| C-8 sterol isomerase | 0 | 1 | 0 | 1 |
| Melanocortin receptor 5 | 0 | 2 | 0 | 2 |
| Mu-type opioid receptor | 0 | 2 | 0 | 2 |
| D(3) dopamine receptor | 0 | 2 | 0 | 2 |
| Sodium channel protein type 1 subunit alpha | 0 | 1 | 0 | 1 |
| Sodium channel protein type 4 subunit alpha | 0 | 1 | 0 | 1 |
| Squalene synthase | 0 | 1 | 0 | 1 |
| Delta-type opioid receptor | 0 | 2 | 0 | 2 |
| Kappa-type opioid receptor | 0 | 2 | 0 | 2 |
| 5-hydroxytryptamine receptor 2B | 0 | 2 | 0 | 2 |
| C-C chemokine receptor type 2 | 0 | 2 | 0 | 2 |
| Melanocortin receptor 3 | 0 | 2 | 0 | 2 |
| Alpha-1A adrenergic receptor | 0 | 2 | 0 | 2 |
| Histamine H2 receptor | 1 | 0 | 0 | 1 |
| D(1A) dopamine receptor | 1 | 0 | 0 | 1 |
| 5-hydroxytryptamine receptor 6 | 0 | 2 | 0 | 2 |
| Carnitine O-palmitoyltransferase 1, liver isoform | 0 | 1 | 0 | 1 |
| C-C chemokine receptor type 4 | 0 | 2 | 0 | 2 |
| Spike glycoprotein | 1 | 0 | 0 | 1 |
| Gamma-aminobutyric acid receptor subunit alpha-1 | 1 | 0 | 0 | 1 |
| Gamma-aminobutyric acid receptor subunit beta-3 | 1 | 0 | 0 | 1 |
| Gamma-aminobutyric acid receptor subunit beta-2 | 1 | 0 | 0 | 1 |
| Sodium channel protein type 7 subunit alpha | 0 | 1 | 0 | 1 |
| Voltage-dependent L-type calcium channel subunit alpha-1D | 0 | 2 | 0 | 2 |
| Sodium-dependent dopamine transporter | 0 | 2 | 0 | 2 |
| Potassium voltage-gated channel subfamily H member 2 | 0 | 2 | 0 | 2 |
| Voltage-dependent L-type calcium channel subunit alpha-1S | 0 | 2 | 0 | 2 |
| Voltage-dependent L-type calcium channel subunit alpha-1C | 0 | 2 | 0 | 2 |
| Sodium channel protein type 5 subunit alpha | 0 | 2 | 0 | 2 |
| Squalene monooxygenase | 0 | 1 | 0 | 1 |
| 3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase | 0 | 1 | 0 | 1 |
| Sodium channel protein type 9 subunit alpha | 0 | 1 | 0 | 1 |
| Lysine-specific demethylase 7A | 0 | 1 | 0 | 1 |
| GABA theta subunit | 1 | 0 | 0 | 1 |
| Carnitine O-palmitoyltransferase 1, muscle isoform | 0 | 1 | 0 | 1 |
| Inositol hexakisphosphate kinase 1 | 1 | 0 | 0 | 1 |
| Canalicular multispecific organic anion transporter 1 | 0 | 1 | 0 | 1 |
| Sodium channel protein type 2 subunit alpha | 0 | 1 | 0 | 1 |
| Ataxin-2 | 1 | 0 | 0 | 1 |
| Sigma non-opioid intracellular receptor 1 | 0 | 2 | 0 | 2 |
| Gamma-aminobutyric acid receptor subunit epsilon | 1 | 0 | 0 | 1 |
| NAD-dependent protein deacetylase sirtuin-3, mitochondrial | 0 | 0 | 1 | 1 |
| Sodium channel protein type 3 subunit alpha | 0 | 1 | 0 | 1 |
| Sodium channel protein type 11 subunit alpha | 0 | 1 | 0 | 1 |
| Histone lysine demethylase PHF8 | 0 | 1 | 0 | 1 |
| Sodium channel protein type 8 subunit alpha | 0 | 1 | 0 | 1 |
| Sodium channel protein type 10 subunit alpha | 0 | 1 | 0 | 1 |
| cytochrome P450 2C9, partial | 1 | 0 | 0 | 1 |
| ATP-dependent phosphofructokinase | 1 | 0 | 0 | 1 |
| cytochrome P450 family 3 subfamily A polypeptide 4 | 1 | 0 | 0 | 1 |
| Cytochrome P450 2C9 | 0 | 1 | 0 | 1 |
| Potassium voltage-gated channel subfamily A member 5 | 0 | 1 | 0 | 1 |
| Cytochrome P450 2J2 | 0 | 1 | 0 | 1 |
| Potassium voltage-gated channel subfamily A member 1 | 0 | 1 | 0 | 1 |
| Potassium voltage-gated channel subfamily D member 2 | 0 | 1 | 0 | 1 |
| Luciferase | 1 | 0 | 0 | 1 |
| vitamin D (1,25- dihydroxyvitamin D3) receptor | 1 | 0 | 0 | 1 |
| [prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023] |