Page last updated: 2024-09-27

Bilateral Diffuse Uveal Melanocytic Proliferation, Paraneoplastic

Ocular manifestations secondary to various NEOPLASMS in which antibodies to antigens of the primary tumor cross-react with ocular antigens. This autoimmune response often leads to visual loss and other ocular dysfunctions.

Synonyms(6)

Synonym
Cancer-Associated Retinopathy
Paraneoplastic Syndromes, Ocular
Paraneoplastic Diseases, Ocular
Melanoma-Associated Retinopathy
Bilateral Diffuse Uveal Melanocytic Proliferation, Paraneoplastic
Paraneoplastic Melanocytic Proliferation

Research

Studies (24)

TimeframeStudies, This Condition (%)All Conditions %
pre-19900 (0.00)23.3326
1990's0 (0.00)12.5806
2000's0 (0.00)18.1394
2010's19 (79.17)28.8240
2020's5 (20.83)9.53
DrugIndicatedRelationship StrengthStudiesTrials
diclofenac0low10
fluorouracil0low10
hydroxychloroquine0low10
prednisolone0low30
prednisone0low20
fluocinolone acetonide0low10
triamcinolone acetonide0low20
methylprednisolone0low10
quinazolines0low10
isoxazoles0low10
triamcinolone0low10
etoposide0low10
propiconazole0low10
fluorodeoxyglucose f180low20
methotrexate0low20
erlotinib hydrochloride0low10
inositol 3-phosphate0low10
mycophenolic acid0low10
trametinib0low10
dabrafenib0low10
levoleucovorin0low10
eye0low10
pyrimidinones0low10

Protein Targets (714)

ProteinPotency MeasurementsInhibition MeasurementsActivation MeasurementsDrugs
Fumarate hydratase2002
PPM1D protein2002
cytochrome P450 family 3 subfamily A polypeptide 45005
EWS/FLI fusion protein6006
G2002
polyprotein2002
Bone morphogenetic protein receptor type-1B0033
Membrane-associated progesterone receptor component 10033
Cell division cycle 7-related protein kinase0022
Serine/threonine-protein kinase PLK40033
ATP-dependent RNA helicase DDX3X0033
Pirin0202
Pyridoxal kinase0033
Citron Rho-interacting kinase0033
Serine/threonine-protein kinase Chk10033
Aurora kinase A0033
Cyclin-G-associated kinase0033
Ephrin type-B receptor 60033
Peroxisomal acyl-coenzyme A oxidase 30033
Receptor-interacting serine/threonine-protein kinase 20134
Mitotic checkpoint serine/threonine-protein kinase BUB10033
Dynamin-like 120 kDa protein, mitochondrial0033
Tyrosine-protein kinase JAK20033
Eukaryotic translation initiation factor 5B0022
Rho-associated protein kinase 20033
Serine/threonine-protein kinase ULK10033
Serine/threonine-protein kinase/endoribonuclease IRE10033
Nuclear receptor subfamily 1 group I member 20022
Ribosomal protein S6 kinase alpha-50033
U5 small nuclear ribonucleoprotein 200 kDa helicase0033
Ribosomal protein S6 kinase alpha-40033
Serine/threonine-protein kinase 160033
Cyclin-dependent kinase-like 50022
Serine/threonine-protein kinase 100033
Serine/threonine-protein kinase D30033
Structural maintenance of chromosomes protein 20033
Mitogen-activated protein kinase kinase kinase 60033
Mitogen-activated protein kinase kinase kinase kinase 40033
Serine/threonine-protein kinase LATS10033
Serine/threonine-protein kinase PAK 40033
Tyrosine-protein kinase ABL10145
Epidermal growth factor receptor0538
GTPase KRas0202
Interferon beta4004
HLA class I histocompatibility antigen, B alpha chain 2002
RAF proto-oncogene serine/threonine-protein kinase0215
High affinity nerve growth factor receptor0033
Guanine nucleotide-binding protein G(i) subunit alpha-20033
ADP/ATP translocase 20033
Protein kinase C beta type0033
Insulin receptor0033
Tyrosine-protein kinase Lck0033
Tyrosine-protein kinase Fyn0134
Cyclin-dependent kinase 10033
Glycogen phosphorylase, liver form0033
Tyrosine-protein kinase Fes/Fps0033
Adenine phosphoribosyltransferase0033
Tyrosine-protein kinase Yes0033
Tyrosine-protein kinase Lyn0033
Proto-oncogene tyrosine-protein kinase receptor Ret0033
Insulin-like growth factor 1 receptor0033
Signal recognition particle receptor subunit alpha0022
Cytochrome c1, heme protein, mitochondrial0033
Hepatocyte growth factor receptor0033
Tyrosine-protein kinase HCK0033
Platelet-derived growth factor receptor beta0033
Tyrosine-protein kinase Fgr0033
Serine/threonine-protein kinase A-Raf0235
Glycogen phosphorylase, brain form0033
Breakpoint cluster region protein0033
Serine/threonine-protein kinase pim-10033
Fibroblast growth factor receptor 10134
DNA topoisomerase 2-alpha01410
Cyclin-dependent kinase 40033
ADP/ATP translocase 30033
Inosine-5'-monophosphate dehydrogenase 20235
Proto-oncogene tyrosine-protein kinase Src0134
cAMP-dependent protein kinase type II-alpha regulatory subunit0033
Serine/threonine-protein kinase B-raf0259
Phosphorylase b kinase gamma catalytic chain, liver/testis isoform0033
Ribosyldihydronicotinamide dehydrogenase [quinone]0033
Tyrosine-protein kinase Fer0033
Protein kinase C alpha type0033
cAMP-dependent protein kinase catalytic subunit alpha0033
General transcription and DNA repair factor IIH helicase subunit XPD0033
Casein kinase II subunit alpha'0033
Ras-related protein Rab-6A0033
Ephrin type-A receptor 10033
Multifunctional protein ADE20033
cAMP-dependent protein kinase catalytic subunit gamma0022
cAMP-dependent protein kinase catalytic subunit beta0033
Ferrochelatase, mitochondrial0044
Ribosomal protein S6 kinase beta-10033
Tyrosine-protein kinase JAK10033
Cyclin-dependent kinase 20044
Beta-adrenergic receptor kinase 10033
Probable ATP-dependent RNA helicase DDX60033
Mitogen-activated protein kinase 3 0033
MAP/microtubule affinity-regulating kinase 30033
Deoxycytidine kinase0033
Mitogen-activated protein kinase 10033
Ephrin type-A receptor 20033
Ephrin type-B receptor 20033
Non-receptor tyrosine-protein kinase TYK20033
UMP-CMP kinase 0033
Phosphatidylethanolamine-binding protein 10033
Wee1-like protein kinase0033
Heme oxygenase 20033
S-adenosylmethionine synthase isoform type-20033
DnaJ homolog subfamily A member 10033
RAC-alpha serine/threonine-protein kinase0033
RAC-beta serine/threonine-protein kinase0033
Dual specificity protein kinase TTK0022
DNA replication licensing factor MCM40033
Myosin-100033
Dual specificity mitogen-activated protein kinase kinase 20336
Receptor-type tyrosine-protein kinase FLT30033
Bone morphogenetic protein receptor type-1A0033
Activin receptor type-1B0033
TGF-beta receptor type-10134
Serine/threonine-protein kinase receptor R30022
TGF-beta receptor type-20033
Electron transfer flavoprotein subunit beta0033
Tyrosine-protein kinase CSK0033
Glycine--tRNA ligase0033
Protein kinase C iota type0033
Exosome RNA helicase MTR40033
Tyrosine-protein kinase Tec0033
Tyrosine-protein kinase ABL20033
Tyrosine-protein kinase FRK0033
Tyrosine-protein kinase SYK0033
26S proteasome regulatory subunit 6B0033
Mitogen-activated protein kinase 80033
Mitogen-activated protein kinase 90033
Dual specificity mitogen-activated protein kinase kinase 40033
Dual specificity mitogen-activated protein kinase kinase 30033
Phosphatidylinositol 5-phosphate 4-kinase type-2 alpha0033
Casein kinase I isoform alpha0033
Casein kinase I isoform delta0033
MAP kinase-activated protein kinase 20033
Elongation factor Tu, mitochondrial0033
Choline-phosphate cytidylyltransferase A0022
Cysteine--tRNA ligase, cytoplasmic0033
Casein kinase I isoform epsilon0033
Very long-chain specific acyl-CoA dehydrogenase, mitochondrial0033
Dual specificity protein kinase CLK10033
Dual specificity protein kinase CLK20033
Dual specificity protein kinase CLK30022
Glycogen synthase kinase-3 alpha0033
Glycogen synthase kinase-3 beta0033
Cyclin-dependent kinase 70033
Cyclin-dependent kinase 90033
Ras-related protein Rab-27A0033
Interleukin-1 receptor-associated kinase 10033
Ribosomal protein S6 kinase alpha-30033
Serine/threonine-protein kinase Nek20033
Serine/threonine-protein kinase Nek30033
Dual specificity mitogen-activated protein kinase kinase 60033
Serine/threonine-protein kinase PLK10033
LIM domain kinase 10033
LIM domain kinase 20033
Mitogen-activated protein kinase 100033
Tyrosine--tRNA ligase, cytoplasmic0033
5'-AMP-activated protein kinase subunit gamma-10033
Ephrin type-B receptor 30033
Ephrin type-A receptor 50033
Ephrin type-B receptor 40033
Ephrin type-A receptor 40033
Adenylate kinase 2, mitochondrial0033
Adenosine kinase0033
Ras-related protein Rab-100033
Actin-related protein 30033
Actin-related protein 20033
GTP-binding nuclear protein Ran0033
Casein kinase I isoform gamma-20033
Cyclin-dependent kinase 30033
Cyclin-dependent kinase 60033
Cyclin-dependent-like kinase 5 0033
Cyclin-dependent kinase 160033
Cyclin-dependent kinase 170033
Heat shock factor protein 10202
ATP-dependent 6-phosphofructokinase, platelet type0033
Dual specificity mitogen-activated protein kinase kinase 10336
DNA topoisomerase 2-beta01411
Protein kinase C theta type0033
Activin receptor type-10033
Macrophage-stimulating protein receptor0033
Focal adhesion kinase 10033
Protein kinase C zeta type0022
Protein kinase C delta type0033
Tyrosine-protein kinase BTK0033
Activated CDC42 kinase 10033
Epithelial discoidin domain-containing receptor 10033
Mitogen-activated protein kinase kinase kinase kinase 20033
Tyrosine-protein kinase Mer0123
Serine/threonine-protein kinase 40033
5'-AMP-activated protein kinase catalytic subunit alpha-10033
Dual specificity mitogen-activated protein kinase kinase 50033
Mitogen-activated protein kinase 70033
Serine/threonine-protein kinase PAK 20033
Serine/threonine-protein kinase 30033
Mitogen-activated protein kinase kinase kinase 10033
Integrin-linked protein kinase0033
Rho-associated protein kinase 10033
Non-receptor tyrosine-protein kinase TNK10033
Receptor-interacting serine/threonine-protein kinase 10101
Calcium/calmodulin-dependent protein kinase type II subunit gamma0033
Calcium/calmodulin-dependent protein kinase type II subunit delta0033
Dual specificity tyrosine-phosphorylation-regulated kinase 1A0033
Activin receptor type-2B0033
Bone morphogenetic protein receptor type-20033
Protein-tyrosine kinase 60033
cGMP-dependent protein kinase 1 0033
Cyclin-dependent kinase 130033
Inhibitor of nuclear factor kappa-B kinase subunit epsilon0033
Protein-tyrosine kinase 2-beta0033
Maternal embryonic leucine zipper kinase0033
Structural maintenance of chromosomes protein 1A0033
Chromodomain-helicase-DNA-binding protein 40033
Peroxisomal acyl-coenzyme A oxidase 10033
Cyclin-dependent kinase 100033
Ephrin type-A receptor 70022
Delta(24)-sterol reductase0033
Ribosomal protein S6 kinase alpha-10033
Dual specificity testis-specific protein kinase 10022
Myosin light chain kinase, smooth muscle0033
Mitogen-activated protein kinase 110033
Serine/threonine-protein kinase STK110033
Serine/threonine-protein kinase N10033
Serine/threonine-protein kinase N20033
Mitogen-activated protein kinase 140033
Calcium/calmodulin-dependent protein kinase type IV0033
Mitogen-activated protein kinase kinase kinase 110033
MAP kinase-activated protein kinase 30022
Discoidin domain-containing receptor 20033
AP2-associated protein kinase 10033
Myosin light chain kinase 30033
Uncharacterized aarF domain-containing protein kinase 50033
Putative heat shock protein HSP 90-beta 20033
Rab-like protein 30033
Serine/threonine-protein kinase MRCK alpha0033
Serine/threonine-protein kinase MRCK gamma0033
Acyl-CoA dehydrogenase family member 100033
Serine/threonine-protein kinase N30033
Serine/threonine-protein kinase ULK30033
Dual serine/threonine and tyrosine protein kinase0101
Uncharacterized protein FLJ452520033
Acyl-CoA dehydrogenase family member 110033
Serine/threonine-protein kinase/endoribonuclease IRE20033
Serine/threonine-protein kinase MARK20033
ATP-dependent RNA helicase DHX300022
Serine/threonine-protein kinase TAO10033
STE20-related kinase adapter protein alpha0033
Myosin-140033
AarF domain-containing protein kinase 10033
ATP-dependent RNA helicase DDX420033
Mitogen-activated protein kinase kinase kinase kinase 30033
MAP kinase-activated protein kinase 50033
Eukaryotic peptide chain release factor GTP-binding subunit ERF3B0033
Misshapen-like kinase 10022
Atypical kinase COQ8A, mitochondrial0033
Phosphatidylinositol 5-phosphate 4-kinase type-2 gamma0033
Mitogen-activated protein kinase 150033
Serine/threonine-protein kinase Nek90033
ATP-dependent RNA helicase DDX10033
Inositol hexakisphosphate kinase 12002
Mitogen-activated protein kinase kinase kinase kinase 10033
Aurora kinase B0033
MAP/microtubule affinity-regulating kinase 40033
Serine/threonine-protein kinase Nek10033
PAS domain-containing serine/threonine-protein kinase0022
Calcium/calmodulin-dependent protein kinase kinase 20033
EKC/KEOPS complex subunit TP53RK0033
Dual specificity testis-specific protein kinase 20033
Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase0033
Mitogen-activated protein kinase kinase kinase 50033
Mitogen-activated protein kinase kinase kinase 30033
Eukaryotic translation initiation factor 2-alpha kinase 10033
Nucleolar GTP-binding protein 10033
Serine/threonine-protein kinase D20033
NUAK family SNF1-like kinase 20033
RNA cytidine acetyltransferase0033
Serine/threonine-protein kinase SIK20033
STE20-like serine/threonine-protein kinase 0033
Serine/threonine-protein kinase TAO30033
dCTP pyrophosphatase 10033
Dual specificity protein kinase CLK40033
Casein kinase I isoform gamma-10033
Serine/threonine-protein kinase PAK 60022
Phenylalanine--tRNA ligase beta subunit0033
Isoleucine--tRNA ligase, mitochondrial0022
BMP-2-inducible protein kinase0033
Obg-like ATPase 10033
Midasin0033
Interleukin-1 receptor-associated kinase 40033
Mitogen-activated protein kinase kinase kinase 200134
Cyclin-dependent kinase 120033
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 130033
Serine/threonine-protein kinase pim-20033
Serine/threonine-protein kinase 260033
Serine/threonine-protein kinase NLK0033
5'-AMP-activated protein kinase subunit gamma-20033
Serine/threonine-protein kinase TBK10033
Septin-90033
Ribosomal protein S6 kinase alpha-60033
TRAF2 and NCK-interacting protein kinase0033
Serine/threonine-protein kinase TAO20033
Serine/threonine-protein kinase ICK0033
RAC-gamma serine/threonine-protein kinase0033
Serine/threonine-protein kinase SIK30033
Mitogen-activated protein kinase kinase kinase 20033
Thyroid hormone receptor-associated protein 30033
Dual specificity tyrosine-phosphorylation-regulated kinase 1B0033
Mitogen-activated protein kinase kinase kinase kinase 50033
Receptor-interacting serine/threonine-protein kinase 30134
Serine/threonine-protein kinase MRCK beta0033
Interleukin-1 receptor-associated kinase 30033
Serine/threonine-protein kinase 240022
Casein kinase I isoform gamma-30033
Mitogen-activated protein kinase kinase kinase 40033
cytochrome P450 2C9, partial2002
Aldo-keto reductase family 1 member B100101
UDP-glucuronosyltransferase 1A90103
Prostaglandin G/H synthase 1 0101
Transient receptor potential cation channel subfamily A member 10011
Bile salt export pump0808
Dihydrofolate reductase0304
Cytochrome c oxidase subunit 20101
Carbonic anhydrase 10101
Carbonic anhydrase 20112
Fatty acid-binding protein, liver0202
Transthyretin0013
Albumin0112
Prostaglandin G/H synthase 10101
Cytochrome P450 3A40303
Interleukin-80101
Calcium/calmodulin-dependent protein kinase type II subunit alpha0101
Cytochrome P450 2C9 0405
Fatty acid-binding protein, intestinal0101
Aldo-keto reductase family 1 member B10101
UDP-glucuronosyltransferase 2B70203
UDP-glucuronosyltransferase 1-60303
UDP-glucuronosyltransferase 1A1 0305
UDP-glucuronosyltransferase 1A40202
Prostaglandin G/H synthase 10101
Sodium- and chloride-dependent GABA transporter 10101
C-X-C chemokine receptor type 10101
Sodium- and chloride-dependent GABA transporter 20101
Sodium- and chloride-dependent GABA transporter 30101
Prostaglandin G/H synthase 20202
Prostaglandin G/H synthase 2 0101
UDP-glucuronosyltransferase 1A30001
UDP-glucuronosyltransferase 2B10 0202
Sodium- and chloride-dependent betaine transporter0101
Cytochrome P450 2J20303
Prostaglandin G/H synthase 20101
Prostaglandin G/H synthase 20101
Carbonic anhydrase 90101
Solute carrier family 22 member 60102
Prostaglandin G/H synthase 1 0101
Carbonic anhydrase 40101
Multidrug and toxin extrusion protein 10101
P2Y purinoceptor 120101
UDP-glucuronosyltransferase 1A70102
UDP-glucuronosyltransferase 1A100102
Receptor tyrosine-protein kinase erbB-20202
Serine/threonine-protein kinase B-raf 0202
glp-1 receptor, partial5005
hypoxia-inducible factor 1 alpha subunit5005
RAR-related orphan receptor gamma7007
SMAD family member 27007
SMAD family member 37007
TDP1 protein100010
GLI family zinc finger 3100010
AR protein130013
caspase 7, apoptosis-related cysteine protease1001
nuclear receptor subfamily 1, group I, member 37007
progesterone receptor110011
glucocorticoid receptor [Homo sapiens]120012
retinoic acid nuclear receptor alpha variant 18008
retinoid X nuclear receptor alpha9009
estrogen-related nuclear receptor alpha120012
pregnane X nuclear receptor110011
estrogen nuclear receptor alpha130013
67.9K protein5005
peroxisome proliferator-activated receptor delta8008
peroxisome proliferator activated receptor gamma7007
vitamin D (1,25- dihydroxyvitamin D3) receptor8008
caspase-31001
LMP1 [Human herpesvirus 4]0001
thyroid stimulating hormone receptor3003
activating transcription factor 62002
nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105), isoform CRA_a3003
v-jun sarcoma virus 17 oncogene homolog (avian)4004
Histone H2A.x4004
chromobox protein homolog 16006
nuclear factor erythroid 2-related factor 2 isoform 29009
thyroid hormone receptor beta isoform 28008
heat shock protein beta-14004
nuclear receptor coactivator 1 isoform 1 [Homo sapiens]0202
nuclear factor erythroid 2-related factor 2 isoform 18008
DNA polymerase iota isoform a (long)5005
urokinase-type plasminogen activator precursor4004
plasminogen precursor4004
urokinase plasminogen activator surface receptor precursor4004
transactivating tegument protein VP16 [Human herpesvirus 1]0202
geminin9009
nuclear receptor coactivator 3 isoform a0202
ATP-binding cassette sub-family C member 30707
Multidrug resistance-associated protein 40708
Voltage-dependent calcium channel gamma-2 subunit6006
Prothrombin0001
Regulatory protein E20011
Cellular tumor antigen p53110011
ATP-dependent translocase ABCB10101
ATP-dependent translocase ABCB10317
DNA topoisomerase 10102
Polyunsaturated fatty acid lipoxygenase ALOX150101
DNA topoisomerase 20001
Glutamate receptor 26107
ATP-dependent translocase ABCB10202
Serum paraoxonase/arylesterase 10202
Glutamate receptor ionotropic, NMDA 1 0001
Caspase-30101
Glutamate receptor ionotropic, NMDA 2A 0001
Glutamate receptor ionotropic, NMDA 2B0001
Glutamate receptor ionotropic, NMDA 2C0001
DNA topoisomerase 2-alpha 0001
Glutamate receptor ionotropic, NMDA 2D0001
Tubulin beta-2B chain0114
Integrase 0101
Similar to alpha-tubulin isoform 1 0114
Similar to alpha-tubulin isoform 1 0103
Glutamate receptor ionotropic, NMDA 3B0001
Canalicular multispecific organic anion transporter 10809
ATPase family AAA domain-containing protein 5100010
Ataxin-2100010
Solute carrier organic anion transporter family member 1B30405
Glutamate receptor ionotropic, NMDA 3A0001
Chain A, 2-oxoglutarate Oxygenase3003
Smad32002
hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)5005
cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a100010
nuclear receptor subfamily 1, group I, member 25005
mitogen-activated protein kinase 12002
lamin isoform A-delta108008
Glucocorticoid receptor012219
Glycine receptor subunit alpha-1012012
Glycine receptor subunit beta012012
Glycine receptor subunit alpha-2012012
Glycine receptor subunit alpha-3012012
Chain A, MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASE2002
Chain A, Uracil Phosphoribosyltransferase0101
Luciferase2002
interleukin 82002
endonuclease IV1001
acetylcholinesterase4004
Skn7p0001
thioredoxin reductase4004
pregnane X receptor5005
ATAD5 protein, partial4004
Microtubule-associated protein tau3003
Thrombopoietin1001
aldehyde dehydrogenase 1 family, member A15005
thyroid stimulating hormone receptor2002
estrogen receptor 2 (ER beta)6006
nonstructural protein 13003
farnesoid X nuclear receptor4004
arylsulfatase A2002
IDH15005
euchromatic histone-lysine N-methyltransferase 25005
peripheral myelin protein 22 isoform 12002
hemoglobin subunit beta1001
huntingtin isoform 21001
flap endonuclease 12002
serine/threonine-protein kinase mTOR isoform 11001
Vpr1001
peripheral myelin protein 225005
survival motor neuron protein isoform d3003
muscleblind-like protein 1 isoform 14004
Solute carrier family 22 member 80001
Amyloid-beta precursor protein1102
Thymidylate synthase0303
Aromatase0101
HSP40, subfamily A [Plasmodium falciparum 3D7]0001
ATP-dependent phosphofructokinase3003
Genome polyprotein 0101
Spike glycoprotein0011
Replicase polyprotein 1ab0011
Transmembrane protease serine 20011
Procathepsin L0011
Muscarinic acetylcholine receptor M20202
Muscarinic acetylcholine receptor M40101
Muscarinic acetylcholine receptor M50101
Alpha-2A adrenergic receptor0101
Replicase polyprotein 1a0011
Replicase polyprotein 1ab0011
Replicase polyprotein 1ab0112
Replicase polyprotein 1ab0112
Muscarinic acetylcholine receptor M10101
Alpha-2B adrenergic receptor0101
Alpha-2C adrenergic receptor0101
Muscarinic acetylcholine receptor M30101
Alpha-1D adrenergic receptor0202
Spike glycoprotein3014
Potassium voltage-gated channel subfamily H member 20101
Sigma intracellular receptor 20101
Cyclic GMP-AMP synthase0101
Sigma non-opioid intracellular receptor 10101
Angiotensin-converting enzyme 2 0011
Toll-like receptor 90101
Toll-like receptor 70101
Chain B, DIHYDROFOLATE REDUCTASE0011
Chain B, DIHYDROFOLATE REDUCTASE0011
Chain A, TYROSYL-DNA PHOSPHODIESTERASE2002
Chain B, DIHYDROFOLATE REDUCTASE0011
Chain A, HADH2 protein4004
Chain B, HADH2 protein4004
Chain A, Ferritin light chain2002
acid sphingomyelinase1001
dopamine D1 receptor1001
ClpP1001
15-lipoxygenase, partial2002
phosphopantetheinyl transferase4004
USP1 protein, partial2002
Thymidylate synthase 0101
alpha-galactosidase1001
Thymidylate synthase 0101
Bloom syndrome protein isoform 12002
cellular tumor antigen p53 isoform a1001
polyunsaturated fatty acid lipoxygenase ALOX121001
15-hydroxyprostaglandin dehydrogenase [NAD(+)] isoform 12002
vitamin D3 receptor isoform VDRA4004
transcriptional regulator ERG isoform 31001
importin subunit beta-1 isoform 11001
DNA polymerase beta1001
snurportin-11001
peptidyl-prolyl cis-trans isomerase NIMA-interacting 11001
DNA polymerase eta isoform 11001
DNA polymerase kappa isoform 11001
M-phase phosphoprotein 81001
histone acetyltransferase KAT2A isoform 11001
caspase-1 isoform alpha precursor1001
Toll-like receptor 40101
Fatty-acid amide hydrolase 10101
Bile salt export pump0101
ATP-binding cassette sub-family C member 30102
Dihydrofolate reductase0203
Dihydrofolate reductase 0101
Dihydrofolate reductase0101
Dihydrofolate reductase0101
Dihydrofolate reductase0203
Thymidylate synthase0101
Thymidylate synthase0202
Integrin beta-31102
Bifunctional dihydrofolate reductase-thymidylate synthase0101
Integrin alpha-IIb1001
5-hydroxytryptamine receptor 2C0102
High mobility group protein B10011
Dihydrofolate reductase0101
Thymidylate synthase0101
Dihydrofolate reductase0224
Glucose-6-phosphate 1-dehydrogenase0101
Bifunctional dihydrofolate reductase-thymidylate synthase0101
Folate receptor beta0101
5-hydroxytryptamine receptor 2A0101
Cytochrome P450 11B1, mitochondrial 0101
Folate receptor alpha0101
Dihydrofolate reductase0202
Histidine decarboxylase0101
Trifunctional purine biosynthetic protein adenosine-30101
Bifunctional purine biosynthesis protein ATIC0202
Multidrug resistance-associated protein 1 0001
Delta-type opioid receptor0101
Mu-type opioid receptor0101
Kappa-type opioid receptor0101
Reduced folate transporter0202
Folylpolyglutamate synthase, mitochondrial0103
6-phosphogluconate dehydrogenase, decarboxylating0101
Caspase-71001
Solute carrier organic anion transporter family member 1A30001
Dihydrofolate reductase0101
Pteridine reductase 10101
Folylpolyglutamate synthase, mitochondrial0103
Bifunctional dihydrofolate reductase-thymidylate synthase0101
TAR DNA-binding protein 434004
Bifunctional dihydrofolate reductase-thymidylate synthase0101
Canalicular multispecific organic anion transporter 10102
Trifunctional purine biosynthetic protein adenosine-30101
Solute carrier family 22 member 200101
Dihydrofolate reductase 0101
Solute carrier family 22 member 80001
Solute carrier family 22 member 60101
Dihydrofolate reductase0101
ATP-binding cassette sub-family C member 110001
Proton-coupled folate transporter0101
Multidrug resistance associated protein0102
Solute carrier family 22 member 110001
Protein-arginine deiminase type-40101
Broad substrate specificity ATP-binding cassette transporter ABCG20001
bromodomain adjacent to zinc finger domain 2B1001
Androgen receptor0303
Nuclear receptor subfamily 1 group I member 20011
Chain A, Inosine-5'-Monophosphate Dehydrogenase 20101
aryl hydrocarbon receptor4004
cytochrome P450 3A4 isoform 13003
lethal factor (plasmid)1001
Gamma-aminobutyric acid receptor subunit pi3003
Gamma-aminobutyric acid receptor subunit beta-13003
Gamma-aminobutyric acid receptor subunit delta3003
Gamma-aminobutyric acid receptor subunit gamma-23003
Glutamate receptor 10101
Glutamate receptor 30101
Glutamate receptor 40101
Gamma-aminobutyric acid receptor subunit alpha-53003
Gamma-aminobutyric acid receptor subunit alpha-33003
Inosine-5'-monophosphate dehydrogenase 1 0202
Gamma-aminobutyric acid receptor subunit gamma-13003
Gamma-aminobutyric acid receptor subunit alpha-23003
Gamma-aminobutyric acid receptor subunit alpha-43003
Gamma-aminobutyric acid receptor subunit gamma-33003
Gamma-aminobutyric acid receptor subunit alpha-63003
Sodium-dependent serotonin transporter0101
Peroxisome proliferator-activated receptor gamma0011
Alpha-synuclein1102
Gamma-aminobutyric acid receptor subunit alpha-13003
Gamma-aminobutyric acid receptor subunit beta-33003
Gamma-aminobutyric acid receptor subunit beta-23003
Inosine-5'-monophosphate dehydrogenase0102
GABA theta subunit3003
Gamma-aminobutyric acid receptor subunit epsilon3003
UDP-glucuronosyltransferase 1A80001
Chain A, Beta-lactamase3003
Genome polyprotein 0101
NPC intracellular cholesterol transporter 1 precursor1001
Tubulin alpha-1A chain0012
Tubulin beta chain0011
Tubulin beta-4A chain0113
Integrin alpha-V 0101
Tubulin beta chain0113
60 kDa chaperonin0101
Tubulin alpha-3C chain0113
Botulinum neurotoxin type A 0101
Apoptosis regulator Bcl-20101
60 kDa heat shock protein, mitochondrial0101
Substance-K receptor0202
Cholecystokinin receptor type A0202
Melanocortin receptor 50202
Delta-type opioid receptor0202
10 kDa heat shock protein, mitochondrial0101
Tubulin alpha-1B chain0113
Tubulin alpha-4A chain0113
Tubulin beta-4B chain0113
Bcl-2-like protein 10101
Tubulin beta-3 chain0214
Tubulin beta-2A chain0113
Thiosulfate sulfurtransferase0101
Beta-tubulin 0101
Tubulin beta-8 chain0113
60 kDa chaperonin 0101
Tubulin alpha-3E chain0113
Tubulin alpha-1A chain0113
10 kDa chaperonin 0101
Tubulin alpha-1C chain0113
Tubulin beta-6 chain0113
Tubulin beta-2B chain0113
Tubulin beta-1 chain0113
Nucleotide-binding oligomerization domain-containing protein 20101
Solute carrier organic anion transporter family member 1B10202
Chain A, AKAP9-BRAF fusion protein0101
tyrosine-protein kinase Yes1001
Vascular endothelial growth factor receptor 20101
G protein-coupled receptor kinase 60022
Dual specificity mitogen-activated protein kinase kinase 40011
Aspartyl/asparaginyl beta-hydroxylase0101
Serine/threonine-protein kinase ATR0011
Serine/threonine-protein kinase Nek70011
Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial0022
Long-chain-fatty-acid--CoA ligase 50011
Serine/threonine-protein kinase 38-like0011
luciferase0001
Estrogen receptor0202
Progesterone receptor0203
Glucocorticoid receptor0112
Glucocorticoid receptor0011
Corticosteroid-binding globulin0101
Mineralocorticoid receptor 0213
Androgen receptor0202
Glutamine synthetase0011
Histamine H1 receptor0011
Nociceptin receptor0011
Estrogen receptor beta0202
thioredoxin glutathione reductase2002
nuclear receptor ROR-gamma isoform 14004
Nuclear receptor ROR-gamma2002
heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)1001
thyroid hormone receptor beta isoform a1001
heat shock protein HSP 90-alpha isoform 20001
Polyunsaturated fatty acid lipoxygenase ALOX15B1001
Histamine H2 receptor1001
Guanine nucleotide-binding protein G1001
heat shock protein 90, putative0001
Chain A, PLASMA RETINOL-BINDING PROTEIN PRECURSOR0011
Chain A, Cruzipain1001
parathyroid hormone/parathyroid hormone-related peptide receptor precursor1001
potassium voltage-gated channel subfamily H member 2 isoform d1001
ubiquitin carboxyl-terminal hydrolase 2 isoform a1001
Retinol-binding protein 40011
Beta-lactoglobulin0011
Disintegrin and metalloproteinase domain-containing protein 171001
Cyclin-dependent kinase 180011
NFKB1 protein, partial1001
procathepsin L isoform 1 preproprotein0101
cytochrome P450 2D61001
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]