Page last updated: 2024-09-27

Benign Neonatal Sleep Myoclonus

Movements or behaviors associated with sleep, sleep stages, or partial arousals from sleep that may impair sleep maintenance. Parasomnias are generally divided into four groups: arousal disorders, sleep-wake transition disorders, parasomnias of REM sleep, and nonspecific parasomnias. (From Thorpy, Sleep Disorders Medicine, 1994, p191)

Synonyms(7)

Synonym
Sensory Paroxysms, Sleep
Myoclonus, Benign Neonatal Sleep
Sleep-Related Abnormal Swallowing Syndrome
Neonatal Sleep Myoclonus, Benign
Benign Neonatal Sleep Myoclonus
Parasomnias
Sleep Drunkenness

Research Excerpts

Overview

ExcerptReference
"Children with parasomnias are not systematically monitored during sleep, although past studies have suggested that patients with sleep terrors or sleepwalking have an elevated level of brief EEG arousals."( Chervin, RD; Guilleminault, C; Palombini, L; Pelayo, R, 2003)
"Parasomnias are abnormal experiences or behaviours that occur during sleep and can be subdivided into disorders of arousal, disorders of rapid eye movement (REM) sleep or other parasomnias."( Lee-Chiong, T; Matwiyoff, G, 2010)
"Non-REM parasomnias are not uncommon conditions in the general population."( d'Ancona, G; Dongol, EM; Drakatos, P; Gildeh, N; Higgins, S; Kent, BD; Leschziner, G; Lyons, E; Macavei, R; Marples, L; Muza, R; Nesbitt, A; Rosenzweig, I; Steier, J; Williams, AJ, 2019)

Treatment

ExcerptReference
"A 30-year-old man, with no history of parasomnias or related precipitating factors, developed sexual behaviour during sleep after three weeks of treatment with escitalopram 10 mg daily."( Krol, DG, 2008)
"The cornerstone of treatment for all parasomnias is adequate patient and bed partner education."( Lee-Chiong, T; Matwiyoff, G, 2010)

Research

Studies (89)

TimeframeStudies, This Condition (%)All Conditions %
pre-19901 (1.12)23.3326
1990's0 (0.00)12.5806
2000's21 (23.60)18.1394
2010's51 (57.30)28.8240
2020's16 (17.98)9.53
DrugIndicatedRelationship StrengthStudiesTrials
gamma-aminobutyric acid0low10
5-hydroxytryptophan0low10
melatonin0low140
caffeine0low10
carbamazepine0low10
cetirizine0low10
chlorpromazine0low10
citalopram0low10
clonazepam0low120
imipramine0low10
indomethacin0low10
methylphenidate0low10
mirtazapine0low10
apnea0low10
nifedipine0low10
omeprazole0low10
prazosin0low30
propofol0low10
pyrimethamine0low10
zaleplon0low10
zolpidem0low30
levodopa0low10
quinoxalines0low10
thiazoles0low20
s,n,n'-tripropylthiocarbamate0low10
sulfadoxine0low10
cetylpyridinium chloride anhydrous0low10
paroxetine0low10
duloxetine hydrochloride0low10
ziprasidone0low10
fanasil, pyrimethamine drug combination0low10
triazoles0low10
sertraline0low10
nsc-1727550low10
tadalafil0low10
pramipexole0low30
varenicline0low10
carnosine0medium11
cotinine0low10
eszopiclone0low10
D-fructopyranose0medium11
topiramate0medium11
dexmedetomidine0low10
u 628400low10
ferryl iron0low10
sodium oxybate0low50
sodium ethylxanthate0low10
suvorexant0low10
warfarin0low10
leptin0low10

Protein Targets (910)

ProteinPotency MeasurementsInhibition MeasurementsActivation MeasurementsDrugs
thioredoxin reductase100010
ATAD5 protein, partial9009
TDP1 protein180018
Microtubule-associated protein tau100010
estrogen-related nuclear receptor alpha220022
arylsulfatase A6006
euchromatic histone-lysine N-methyltransferase 2240024
Bloom syndrome protein isoform 17007
D(1A) dopamine receptor100010
lamin isoform A-delta10140014
neuropeptide S receptor isoform A3003
acetylcholinesterase110011
cytochrome P450 family 3 subfamily A polypeptide 4170017
histone acetyltransferase KAT2A isoform 15005
hypoxia-inducible factor 1 alpha subunit7007
RAR-related orphan receptor gamma190019
GLI family zinc finger 3190019
AR protein200020
aldehyde dehydrogenase 1 family, member A19009
hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)7007
nuclear receptor subfamily 1, group I, member 3170017
progesterone receptor130013
regulator of G-protein signaling 48008
retinoic acid nuclear receptor alpha variant 1200020
retinoid X nuclear receptor alpha110011
farnesoid X nuclear receptor130013
pregnane X nuclear receptor180018
estrogen nuclear receptor alpha250025
cytochrome P450 2D6130013
peroxisome proliferator activated receptor gamma120012
vitamin D (1,25- dihydroxyvitamin D3) receptor110011
cytochrome P450 2D6 isoform 1100010
cytochrome P450 2C9 precursor7007
chromobox protein homolog 19009
potassium voltage-gated channel subfamily H member 2 isoform d7007
thyroid hormone receptor beta isoform 2160016
nuclear factor erythroid 2-related factor 2 isoform 1120012
cytochrome P450 3A4 isoform 1100010
muscarinic acetylcholine receptor M18008
Gamma-aminobutyric acid receptor subunit pi109120
Solute carrier family 22 member 20404
Bile salt export pump0404
Voltage-dependent calcium channel gamma-2 subunit8008
Bile salt export pump025025
5-hydroxytryptamine receptor 1A09413
5-hydroxytryptamine receptor 2C0909
Beta-2 adrenergic receptor0202
Angiotensin-converting enzyme 0101
D(2) dopamine receptor013217
5-hydroxytryptamine receptor 2A011011
Gamma-aminobutyric acid receptor subunit beta-1109120
Alpha-1B adrenergic receptor015217
Beta-1 adrenergic receptor0202
Gamma-aminobutyric acid receptor subunit delta109120
Gamma-aminobutyric acid receptor subunit gamma-2109221
D010010
D(3) dopamine receptor0718
5-hydroxytryptamine receptor 1A0808
Alpha-2B adrenergic receptor09110
Glutamate receptor 28008
Gamma-aminobutyric acid receptor subunit alpha-5109120
Gamma-aminobutyric acid receptor subunit alpha-3109120
D(2) dopamine receptor0202
Alpha-2C adrenergic receptor09110
Alpha-2A adrenergic receptor010111
Gamma-aminobutyric acid receptor subunit gamma-1109120
Gamma-aminobutyric acid receptor subunit alpha-2109120
Alpha-1D adrenergic receptor013215
Alpha-1D adrenergic receptor011114
D(1B) dopamine receptor0606
Beta-3 adrenergic receptor0202
5-hydroxytryptamine receptor 2A012114
5-hydroxytryptamine receptor 2C014014
Gamma-aminobutyric acid receptor subunit alpha-4109120
Gamma-aminobutyric acid receptor subunit gamma-3109120
5-hydroxytryptamine receptor 1B0707
5-hydroxytryptamine receptor 1D0404
Gamma-aminobutyric acid receptor subunit alpha-6109120
D(4) dopamine receptor0606
5-hydroxytryptamine receptor 1F0404
5-hydroxytryptamine receptor 2B0707
5-hydroxytryptamine receptor 70707
D(3) dopamine receptor09213
5-hydroxytryptamine receptor 2B015015
Alpha-1A adrenergic receptor016218
5-hydroxytryptamine receptor 3A0618
Histamine H2 receptor101011
5-hydroxytryptamine receptor 60607
Spike glycoprotein141116
D(2) dopamine receptor013115
Gamma-aminobutyric acid receptor subunit alpha-1109221
Gamma-aminobutyric acid receptor subunit beta-3109120
Gamma-aminobutyric acid receptor subunit beta-2109221
Potassium voltage-gated channel subfamily H member 2020020
Alpha-2A adrenergic receptor0202
D0101
5-hydroxytryptamine receptor 2A0101
Multidrug and toxin extrusion protein 20404
GABA theta subunit109120
D0303
Multidrug and toxin extrusion protein 10606
Sigma non-opioid intracellular receptor 1013013
Gamma-aminobutyric acid receptor subunit epsilon109120
Lysosomal alpha-glucosidase0101
ATP-dependent phosphofructokinase100010
Chain A, Glycogen Phosphorylase0101
Chain A, Glycogen phosphorylase, liver form0011
Chain A, glycogen phosphorylase, liver form0011
Chain A, Glycogen phosphorylase, liver form0011
Chain A, Glycogen phosphorylase, liver form0011
Chain A, Chitinase0101
phosphopantetheinyl transferase9009
GLS protein7007
glucocorticoid receptor [Homo sapiens]170017
thyroid stimulating hormone receptor7007
v-jun sarcoma virus 17 oncogene homolog (avian)120012
atrial natriuretic peptide receptor 1 precursor2002
thyroid hormone receptor beta isoform a6006
DNA polymerase beta1001
nuclear receptor ROR-gamma isoform 18008
geminin140014
DNA polymerase kappa isoform 14004
lethal factor (plasmid)3003
ATP-binding cassette sub-family C member 3019019
Multidrug resistance-associated protein 4019019
Potassium channel subfamily K member 20123
Glycogen phosphorylase, muscle form0101
Renin0101
Carbonic anhydrase 10408
Carbonic anhydrase 20419
Cholinesterase0202
Glycogen phosphorylase, liver form0101
Glycogen phosphorylase, muscle form0101
Replicase polyprotein 1ab0213
Adenosine receptor A30303
Replicase polyprotein 1ab0213
Amine oxidase [flavin-containing] A0202
Acetylcholinesterase0303
Adenosine receptor A10305
Amine oxidase [flavin-containing] B0303
cAMP-specific 3',5'-cyclic phosphodiesterase 4A0202
Adenosine receptor A30101
Adenosine receptor A2a0315
Adenosine receptor A2b0102
Adenosine receptor A2b0203
Adenosine receptor A10316
Adenosine receptor A2a0407
Vasopressin V2 receptor0001
Serine/threonine-protein kinase mTOR0101
Adenosine receptor A2a0101
Adenosine receptor A10101
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform 0101
DNA-dependent protein kinase catalytic subunit0101
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B0101
Adenylate cyclase type 10001
Chitotriosidase-10101
Serine-protein kinase ATM0101
Serine/threonine-protein kinase ATR0101
Adenosine receptor A2b0102
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C0101
Palmitoleoyl-protein carboxylesterase NOTUM0224
Endochitinase B10101
Muscarinic acetylcholine receptor0102
Canalicular multispecific organic anion transporter 1018018
Phosphodiesterase 0101
Broad substrate specificity ATP-binding cassette transporter ABCG20304
Guanine deaminase0101
Chain A, Beta-lactamase5005
USP1 protein, partial110011
thyroid stimulating hormone receptor7007
IDH16006
cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a130013
nuclear factor erythroid 2-related factor 2 isoform 22002
mitogen-activated protein kinase 17007
Vpr1001
Albumin0033
Major prion protein0033
Cellular tumor antigen p53180018
Sodium channel protein type 1 subunit alpha0101
Sodium channel protein type 2 subunit alpha0202
Sodium channel protein type 3 subunit alpha0101
Cytochrome P450 2C9 0909
UDP-glucuronosyltransferase 2B70203
Cytochrome P450 2B60011
Sodium channel protein type 4 subunit alpha0405
Cytochrome P450 2J20606
Sodium channel protein type 9 subunit alpha0505
Frizzled-80011
P2X purinoceptor 40202
cytochrome P450 2C19 precursor5005
Carbonic anhydrase 40105
5-hydroxytryptamine receptor 1D0203
Solute carrier family 15 member 10101
Solute carrier family 15 member 20101
Solute carrier family 15 member 20101
Carbonic anhydrase 40203
atrial natriuretic peptide receptor 2 precursor6006
Histamine H1 receptor010112
Angiopoietin-1 receptor0011
Histamine H4 receptor0213
Chain A, Ferritin light chain4004
SMAD family member 24004
SMAD family member 34004
caspase 7, apoptosis-related cysteine protease5005
estrogen receptor 2 (ER beta)8008
67.9K protein8008
peroxisome proliferator-activated receptor delta9009
caspase-35005
heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)4004
activating transcription factor 65005
thyrotropin-releasing hormone receptor1001
vitamin D3 receptor isoform VDRA6006
heat shock protein beta-19009
survival motor neuron protein isoform d6006
Caspase-20011
Inositol monophosphatase 12002
ATPase family AAA domain-containing protein 58008
Ataxin-2120012
Chain A, TYROSYL-DNA PHOSPHODIESTERASE6006
Proteasome subunit beta type-110001
Fumarate hydratase7007
NFKB1 protein, partial2002
Thrombopoietin2002
Smad36006
NADPH oxidase 10101
G100010
polyprotein7007
Snq2p0002
Adenylate cyclase type 1 0202
Histone H2A.x5005
Caspase-72002
Spike glycoprotein0112
Replicase polyprotein 1ab0112
cellular tumor antigen p53 isoform a5005
caspase-32002
histone deacetylase 9 isoform 32002
ras-related protein Rab-9A6006
serine/threonine-protein kinase mTOR isoform 17007
peripheral myelin protein 22110011
M-phase phosphoprotein 87007
Proteasome subunit alpha type-70001
Solute carrier family 22 member 1 0808
Polyunsaturated fatty acid lipoxygenase ALOX15B5005
Transmembrane protease serine 20112
Glutamate receptor ionotropic, NMDA 2D0101
Transient receptor potential cation channel subfamily V member 10101
Glutamate receptor ionotropic, NMDA 3B0101
Voltage-dependent L-type calcium channel subunit alpha-1F0505
5-hydroxytryptamine receptor 4010010
Epidermal growth factor receptor0303
Interferon beta150015
HLA class I histocompatibility antigen, B alpha chain 100010
Albumin0145
Sarcoplasmic/endoplasmic reticulum calcium ATPase 10101
Receptor tyrosine-protein kinase erbB-20101
Major prion protein0011
Integrin beta-34105
Cytochrome P450 1A20315
Tyrosine-protein kinase Fyn0202
Procathepsin L0213
Aldo-keto reductase family 1 member B1010010
Muscarinic acetylcholine receptor M20809
Muscarinic acetylcholine receptor M40708
ATP-dependent translocase ABCB108010
Muscarinic acetylcholine receptor M10202
Muscarinic acetylcholine receptor M30202
Muscarinic acetylcholine receptor M40202
Integrin alpha-IIb4105
Muscarinic acetylcholine receptor M50202
Muscarinic acetylcholine receptor M50708
Alpha-2A adrenergic receptor011113
Replicase polyprotein 1a0112
Replicase polyprotein 1ab0112
Cys-loop ligand-gated ion channel0101
Calmodulin-10213
Cytochrome P450 2D60617
Muscarinic acetylcholine receptor M20202
Muscarinic acetylcholine receptor M10809
Polyunsaturated fatty acid lipoxygenase ALOX150404
Angiotensin-converting enzyme010010
Sphingomyelin phosphodiesterase0202
Alpha-2B adrenergic receptor09010
Alpha-2C adrenergic receptor011113
Muscarinic acetylcholine receptor M30607
Proteasome subunit beta type-10001
Substance-K receptor0202
D(1A) dopamine receptor0416
D(4) dopamine receptor0719
D(1B) dopamine receptor0203
Adenylate cyclase type 30202
UDP-glucuronosyltransferase 1A40204
Sodium-dependent noradrenaline transporter 014216
Sodium-dependent dopamine transporter011112
Histamine H2 receptor0325
Proteasome subunit alpha type-10001
Proteasome subunit alpha type-20001
Proteasome subunit alpha type-30001
Proteasome subunit alpha type-40001
Adenylate cyclase type 20202
Adenylate cyclase type 40202
Proteasome subunit beta type-80001
Proteasome subunit beta type-90001
Proteasome subunit alpha type-50001
Proteasome subunit beta type-40001
Proteasome subunit beta type-60001
Proteasome subunit beta type-50001
Trypanothione reductase0202
Histamine H1 receptor0101
Sodium-dependent serotonin transporter013316
Melanocortin receptor 40202
5-hydroxytryptamine receptor 7 0303
Melanocortin receptor 50404
Pleiotropic ABC efflux transporter of multiple drugs0204
Mu-type opioid receptor0415
Glutamate receptor ionotropic, NMDA 1 0204
Sodium channel protein type 1 subunit alpha0303
Adenylate cyclase type 80202
Proteasome subunit beta type-100001
Delta-type opioid receptor0505
Kappa-type opioid receptor0404
Melanocortin receptor 30202
Proteasome subunit beta type-30001
Proteasome subunit beta type-20001
D(1A) dopamine receptor5005
5-hydroxytryptamine receptor 70505
Gastrin/cholecystokinin type B receptor0101
Proteasome subunit alpha type-60012
Calmodulin 0112
Aldehyde oxidase 10101
Glutamate receptor ionotropic, NMDA 2A 0204
Glutamate receptor ionotropic, NMDA 2B0305
Glutamate receptor ionotropic, NMDA 2C0305
Sodium channel protein type 7 subunit alpha0303
Voltage-dependent L-type calcium channel subunit alpha-1D 0505
Sodium-dependent dopamine transporter 010212
Adenylate cyclase type 60202
Adenylate cyclase type 50202
Glutamate receptor ionotropic, NMDA 10101
Aldehyde oxidase0202
Glutamate receptor ionotropic, NMDA 2A0101
Glutamate receptor ionotropic, NMDA 2B0101
Voltage-dependent L-type calcium channel subunit alpha-1S0505
Voltage-dependent L-type calcium channel subunit alpha-1C0607
Sodium channel protein type 5 subunit alpha0404
Glutamate receptor ionotropic, NMDA 2C0101
Glutamate receptor ionotropic, NMDA 2D0204
Nuclear receptor subfamily 3 group C member 3 010010
Adenylyl cyclase 7 0202
Proteasome subunit alpha-type 80001
Glutamate receptor ionotropic, NMDA 3A0101
Glutamate receptor ionotropic, NMDA 3B0204
Inositol hexakisphosphate kinase 1100010
Sodium channel protein type 2 subunit alpha0303
Proteasome subunit beta type-70001
Angiotensin-converting enzyme 2 0112
Sodium channel protein type 3 subunit alpha0303
Glutamate receptor ionotropic, NMDA 3A0204
Sodium channel protein type 11 subunit alpha0303
Sodium channel protein type 8 subunit alpha0303
Histamine H3 receptor0202
Sodium channel protein type 10 subunit alpha0303
cytochrome P450 2C9, partial100010
EWS/FLI fusion protein120012
NPC intracellular cholesterol transporter 1 precursor4004
Sodium-dependent noradrenaline transporter0303
Tryptophan 5-hydroxylase 10101
Aldo-keto reductase family 1 member B10303
Aromatase0101
Sodium-dependent serotonin transporter0718
Sigma intracellular receptor 20404
Sodium-dependent serotonin transporter0303
Sodium-dependent dopamine transporter0303
Sigma non-opioid intracellular receptor 10606
Transporter0909
Gamma-aminobutyric acid receptor subunit pi0303
Gamma-aminobutyric acid receptor subunit delta0303
Gamma-aminobutyric acid receptor subunit alpha-10102
Gamma-aminobutyric acid receptor subunit beta-10102
Neuronal acetylcholine receptor subunit alpha-40628
Gamma-aminobutyric acid receptor subunit alpha-20102
Gamma-aminobutyric acid receptor subunit alpha-30102
Neuronal acetylcholine receptor subunit beta-20527
Gamma-aminobutyric acid receptor subunit alpha-106410
Gamma-aminobutyric acid receptor subunit beta-10426
Gamma-aminobutyric acid receptor subunit gamma-206410
Gamma-aminobutyric acid receptor subunit alpha-40102
Gamma-aminobutyric acid receptor subunit gamma-20102
Gamma-aminobutyric acid receptor subunit beta-30538
Translocator protein0101
Translocator protein0101
Cholecystokinin receptor type A0202
Gastrin/cholecystokinin type B receptor0202
Gamma-aminobutyric acid receptor subunit alpha-50549
Gamma-aminobutyric acid receptor subunit alpha-30549
Gamma-aminobutyric acid receptor subunit alpha-20549
Gamma-aminobutyric acid receptor subunit beta-20549
Gamma-aminobutyric acid receptor subunit alpha-40527
Gamma-aminobutyric acid receptor subunit epsilon0303
Gamma-aminobutyric acid receptor subunit alpha-60527
Gamma-aminobutyric acid receptor subunit gamma-10303
Gamma-aminobutyric acid receptor subunit gamma-30314
Gamma-aminobutyric acid receptor subunit theta0303
GALC protein2002
flap endonuclease 13003
Cytochrome P450 3A40809
Cytochrome P450 2A60101
Cytochrome P450 2A50101
Alpha-1B adrenergic receptor 0011
Alpha-1A adrenergic receptor0112
glp-1 receptor, partial4004
aryl hydrocarbon receptor100010
nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105), isoform CRA_a100010
importin subunit beta-1 isoform 13003
snurportin-13003
GTP-binding nuclear protein Ran isoform 12002
urokinase-type plasminogen activator precursor5005
plasminogen precursor5005
urokinase plasminogen activator surface receptor precursor5005
Alpha-synuclein1001
Luciferase7007
Nuclear receptor subfamily 1 group I member 20011
Delta-type opioid receptor0404
Delta-type opioid receptor0606
Mu-type opioid receptor0617
Kappa-type opioid receptor0202
Kappa-type opioid receptor0202
Mu-type opioid receptor0101
Mu-type opioid receptor0404
Sigma non-opioid intracellular receptor 10202
Gamma-aminobutyric acid 0011
Gamma-aminobutyric acid receptor subunit rho-30011
Hsf1 protein0011
bromodomain adjacent to zinc finger domain 2B6006
transcriptional regulator ERG isoform 31001
histone-lysine N-methyltransferase 2A isoform 2 precursor4004
Histone deacetylase 30101
Gamma-aminobutyric acid type B receptor subunit 20011
Gamma-aminobutyric acid type B receptor subunit 20101
Gamma-aminobutyric acid receptor subunit alpha-60011
Gamma-aminobutyric acid receptor subunit gamma-20011
Gamma-aminobutyric acid receptor subunit delta0011
Sodium- and chloride-dependent GABA transporter 10303
Gamma-aminobutyric acid receptor subunit rho-10022
Gamma-aminobutyric acid receptor subunit alpha-20011
Gamma-aminobutyric acid receptor subunit alpha-30011
Gamma-aminobutyric acid receptor subunit gamma-30011
Gamma-aminobutyric acid receptor subunit rho-20011
Sodium- and chloride-dependent GABA transporter 10101
Sodium- and chloride-dependent taurine transporter0101
Sodium- and chloride-dependent GABA transporter 20303
Sodium- and chloride-dependent GABA transporter 30303
Sodium- and chloride-dependent GABA transporter 10101
Sodium- and chloride-dependent GABA transporter 20101
Sodium- and chloride-dependent GABA transporter 30101
Sodium- and chloride-dependent betaine transporter0303
Sodium- and chloride-dependent betaine transporter0101
Sodium- and chloride-dependent GABA transporter 30101
Gamma-aminobutyric acid receptor subunit beta-10011
Histone deacetylase 40101
Gamma-aminobutyric acid receptor subunit alpha-10011
Gamma-aminobutyric acid receptor subunit beta-30011
4-aminobutyrate aminotransferase, mitochondrial0001
4-aminobutyrate aminotransferase, mitochondrial0001
TAR DNA-binding protein 432002
Histone deacetylase 10101
Sterol O-acyltransferase 10011
Proton-coupled amino acid transporter 10101
Gamma-aminobutyric acid receptor subunit alpha-50011
Gamma-aminobutyric acid receptor subunit pi0011
Histone deacetylase 70101
Histone deacetylase 20101
Polyamine deacetylase HDAC100101
Histone deacetylase 11 0101
Histone deacetylase 80101
Gamma-aminobutyric acid receptor subunit alpha-40011
Platelet glycoprotein VI0011
Gamma-aminobutyric acid receptor subunit theta0011
Sodium- and chloride-dependent GABA transporter 20101
Gamma-aminobutyric acid receptor subunit gamma-10011
Histone deacetylase 60101
Gamma-aminobutyric acid type B receptor subunit 10011
Histone deacetylase 90101
Histone deacetylase 50101
Gamma-aminobutyric acid type B receptor subunit 10101
peptidyl-prolyl cis-trans isomerase NIMA-interacting 12002
Voltage-dependent L-type calcium channel subunit alpha-1C0202
Solute carrier family 22 member 30303
Prostaglandin G/H synthase 10304
5-hydroxytryptamine receptor 60202
Histamine H1 receptor0202
Cytochrome P450 2C190305
5-hydroxytryptamine receptor 2C 0101
5-hydroxytryptamine receptor 5A0202
5-hydroxytryptamine receptor 5B0202
UDP-glucuronosyltransferase 1A30001
5-hydroxytryptamine receptor 3A0314
D(2) dopamine receptor0101
Voltage-dependent N-type calcium channel subunit alpha-1B0101
Envelope glycoprotein0033
5-hydroxytryptamine receptor 4 0202
Solute carrier family 22 member 10102
5-hydroxytryptamine receptor 3B0314
Solute carrier family 22 member 20102
Chain A, MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASE4004
Chain A, membrane-associated prostaglandin E synthase-20101
Chain A, Putative fructose-1,6-bisphosphate aldolase4004
Chain A, 2-oxoglutarate Oxygenase100010
Chain A, Cruzipain1001
interleukin 82002
glucocerebrosidase2002
Parkin2002
peripheral myelin protein 22 isoform 14004
DNA polymerase iota isoform a (long)6006
Prostaglandin-H2 D-isomerase0101
Prostaglandin E synthase0101
Solute carrier family 22 member 60101
Prostaglandin G/H synthase 1 0102
Prostaglandin G/H synthase 2 0102
3',5'-cyclic-AMP phosphodiesterase 0101
Solute carrier organic anion transporter family member 2B1 0202
Cytochrome c oxidase subunit 20101
Phospholipase A2, major isoenzyme0101
Interleukin-80101
Androgen receptor0011
Polyunsaturated fatty acid 5-lipoxygenase0102
Aldo-keto reductase family 1 member B10101
Aldo-keto reductase family 1 member C40101
Prostaglandin G/H synthase 10101
Prostaglandin G/H synthase 10202
Thromboxane-A synthase 0202
Serum paraoxonase/arylesterase 10101
Indoleamine 2,3-dioxygenase 10202
Caspase-10001
Nitric oxide synthase, inducible0101
Substance-P receptor0202
Prostaglandin E2 receptor EP3 subtype0101
Prostaglandin E2 receptor EP4 subtype0101
Multidrug resistance-associated protein 1 0101
Bifunctional epoxide hydrolase 20101
Prostaglandin G/H synthase 20213
Prostaglandin G/H synthase 2 0101
Prostaglandin E2 receptor EP1 subtype0101
Peroxisome proliferator-activated receptor gamma0011
Aldo-keto reductase family 1 member C30202
C-X-C chemokine receptor type 30101
Nuclear receptor ROR-gamma4004
Aldo-keto reductase family 1 member C2 0101
Guanine nucleotide-binding protein G1001
Prostaglandin D2 receptor 0202
Solute carrier organic anion transporter family member 1A30101
Prostaglandin G/H synthase 20202
Lactoylglutathione lyase0101
Aldo-keto reductase family 1 member C10101
Prostaglandin G/H synthase 20102
Uracil nucleotide/cysteinyl leukotriene receptor0202
Solute carrier family 22 member 60101
Solute carrier family 22 member 70001
Prostaglandin E2 receptor EP2 subtype0101
Rho-associated protein kinase 20101
Prostaglandin G/H synthase 1 0101
Nicotinate phosphoribosyltransferase0101
Solute carrier family 22 member 80101
Dehydrogenase/reductase SDR family member 90101
P2Y purinoceptor 120101
Solute carrier organic anion transporter family member 1B30202
Cytosolic phospholipase A2 gamma0101
Prostaglandin D2 receptor 20112
Solute carrier organic anion transporter family member 1B10202
Neuronal acetylcholine receptor subunit beta-20516
Neuronal acetylcholine receptor subunit alpha-70202
Chain A, HADH2 protein7007
Chain B, HADH2 protein7007
Chain A, JmjC domain-containing histone demethylation protein 3A3003
Chain A, ATP-DEPENDENT DNA HELICASE Q11001
dopamine D1 receptor1001
15-lipoxygenase, partial1001
WRN1001
integrase, partial0101
lens epithelium-derived growth factor p750101
apical membrane antigen 1, AMA12002
pyruvate kinase1001
hexokinase-4 isoform 11001
glucokinase regulatory protein1001
ubiquitin carboxyl-terminal hydrolase 2 isoform a1001
DNA polymerase eta isoform 11001
Polyphenol oxidase 20001
Carbonic anhydrase 120104
Plasma kallikrein0002
Tyrosine-protein kinase Lck0101
Carbonic anhydrase 30103
Tyrosinase0101
Carbonic anhydrase 60104
Carbonic anhydrase 5A, mitochondrial0115
Carbonic anhydrase0103
Carbonic anhydrase 70104
Solute carrier family 15 member 10101
Carbonic anhydrase0103
Large neutral amino acids transporter small subunit 10202
SLC16A10 protein0002
Carbonic anhydrase 90104
Carbonic anhydrase 0103
Carbonic anhydrase-like protein, putative0002
Carbonic anhydrase0103
Carbonic anhydrase0103
Carbonic anhydrase 0103
Monocarboxylate transporter 100002
Carbonic anhydrase 150103
Carbonic anhydrase 130104
Carbonic anhydrase 140104
Carbonic anhydrase 5B, mitochondrial0104
phosphoglycerate kinase1001
ClpP2002
15-hydroxyprostaglandin dehydrogenase [NAD(+)] isoform 16006
Cytochrome P450 1A10101
Cytochrome P450 1A2 0101
Myeloperoxidase0303
Cytochrome P450 2C11 0101
Aromatase0101
Ribosyldihydronicotinamide dehydrogenase [quinone]0303
Metabotropic glutamate receptor 10101
Acetylcholinesterase 0101
Nociceptin receptor0101
Melatonin receptor type 1A0213
Melatonin receptor type 1C0011
Melatonin receptor type 1A0112
Melatonin receptor type 1B0213
Melatonin receptor type 1C0112
Melatonin receptor type 1B0112
Nuclear factor erythroid 2-related factor 20001
Cytochrome P450 1B10101
Carboxylic ester hydrolase 0101
ATP-dependent translocase ABCB10101
Translocator protein0202
UDP-glucuronosyltransferase 1-60202
ATP-dependent translocase ABCB10101
UDP-glucuronosyltransferase 1A1 0202
UDP-glucuronosyltransferase 2B10 0202
Alpha-1A adrenergic receptor06111
Type-2 angiotensin II receptor0101
Angiotensin-converting enzyme0101
pregnane X receptor2002
hypothetical protein, conserved1001
nonstructural protein 12002
beta-2 adrenergic receptor1001
tumor necrosis factor1001
polyunsaturated fatty acid lipoxygenase ALOX121001
perilipin-50101
perilipin-10101
serine/threonine-protein kinase PLK12002
eyes absent homolog 2 isoform a1001
1-acylglycerol-3-phosphate O-acyltransferase ABHD5 isoform a0101
muscleblind-like protein 1 isoform 11001
Glutathione reductase, mitochondrial0202
Phospholipase A2, membrane associated0001
Voltage-dependent L-type calcium channel subunit alpha-1C0303
Potassium voltage-gated channel subfamily A member 50101
3-oxo-5-alpha-steroid 4-dehydrogenase 1 0101
Platelet-activating factor receptor0001
Voltage-dependent L-type calcium channel subunit alpha-1D0202
3-oxo-5-alpha-steroid 4-dehydrogenase 20101
C-C chemokine receptor type 20202
Voltage-dependent L-type calcium channel subunit alpha-1C0101
Voltage-dependent L-type calcium channel subunit alpha-1S0202
Voltage-dependent L-type calcium channel subunit alpha-1S0101
Potassium voltage-gated channel subfamily A member 10101
C-terminal-binding protein 11001
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C0202
Leukotriene B4 receptor 10001
Myosin light chain kinase, smooth muscle0101
Transient receptor potential cation channel subfamily A member 10011
Potassium channel subfamily K member 2 0101
Beta-2 adrenergic receptor0001
Indoleamine 2,3-dioxygenase 20101
Voltage-dependent L-type calcium channel subunit alpha-1D0101
Voltage-dependent L-type calcium channel subunit alpha-1F0101
Leukotriene B4 receptor 20001
Mcl-10101
huntingtin isoform 21001
pyruvate kinase PKM isoform a1001
cGMP-specific 3',5'-cyclic phosphodiesterase0314
N(G),N(G)-dimethylarginine dimethylaminohydrolase 10101
Sodium/potassium-transporting ATPase subunit alpha-1 0101
Sodium/potassium-transporting ATPase subunit beta-10101
Sodium/potassium-transporting ATPase subunit alpha-30101
Sodium/potassium-transporting ATPase subunit beta-20101
Bifunctional cytochrome P450/NADPH--P450 reductase0011
Potassium-transporting ATPase subunit beta0101
Potassium-transporting ATPase alpha chain 10101
Potassium-transporting ATPase alpha chain 10101
Bombesin receptor subtype-30011
Fatty acid synthase0202
Sodium/potassium-transporting ATPase subunit alpha-20101
Potassium-transporting ATPase subunit beta0101
Potassium-transporting ATPase alpha chain 20001
Sodium/potassium-transporting ATPase subunit beta-30101
Sodium/potassium-transporting ATPase subunit gamma0101
WD repeat-containing protein 50101
Glutathione S-transferase omega-10101
Histone-lysine N-methyltransferase 2A0101
Sodium/potassium-transporting ATPase subunit alpha-40101
Cytosolic endo-beta-N-acetylglucosaminidase0101
5-hydroxytryptamine receptor 3E0214
5-hydroxytryptamine receptor 3A0011
5-hydroxytryptamine receptor 3B0214
Interleukin-6 receptor subunit alpha0101
5-hydroxytryptamine receptor 3A0101
Neuronal acetylcholine receptor subunit beta-40314
Neuronal acetylcholine receptor subunit alpha-30314
Neuronal acetylcholine receptor subunit alpha-40415
Neuronal acetylcholine receptor subunit alpha-70101
Thyrotropin-releasing hormone receptor0101
Neuronal acetylcholine receptor subunit alpha-70415
Glycine receptor subunit alpha-40101
5-hydroxytryptamine receptor 3D0214
5-hydroxytryptamine receptor 3C0214
5-hydroxytryptamine receptor 3B0101
Histamine H3 receptor0101
Leukotriene B4 receptor 10101
Nischarin0101
Quinolone resistance protein NorA0101
Beta-adrenergic receptor kinase 10101
Potassium voltage-gated channel subfamily A member 30101
Beta-adrenergic receptor kinase 10112
Substance-P receptor0101
Rhodopsin kinase GRK10101
G protein-coupled receptor kinase 50101
G protein-coupled receptor kinase 50101
P2X purinoceptor 40101
Rhodopsin kinase GRK10101
Beta-adrenergic receptor kinase 10001
Beta-2 adrenergic receptor0101
Beta-3 adrenergic receptor0101
5-hydroxytryptamine receptor 1B0202
5-hydroxytryptamine receptor 1E0101
5-hydroxytryptamine receptor 5A0101
alpha-galactosidase1001
lysosomal alpha-glucosidase preproprotein1001
interferon gamma precursor0001
Alpha-1A adrenergic receptor0112
Beta-casein0101
Interstitial collagenase0101
Matrix metalloproteinase-90101
Alpha-1B adrenergic receptor0101
Alpha-2A adrenergic receptor0101
Alpha-mannosidase 2C10011
Bromodomain-containing protein 20202
Alpha-2B adrenergic receptor0101
3-oxo-5-alpha-steroid 4-dehydrogenase 20202
Type-1 angiotensin II receptor0101
Alpha-1B adrenergic receptor0417
Alpha-2C adrenergic receptor0101
Alpha-2A adrenergic receptor0101
Chain A, Ferritin light chain0011
Chain A, Ferritin light chain0011
Chain A, Ferritin light chain0011
Chain A, Ferritin light chain0011
Chain A, Ferritin light chain0011
Chain A, Ferritin light chain0011
Chain A, Ferritin light chain0011
Fatty-acid amide hydrolase 10101
UDP-glucuronosyltransferase 1A90001
Fatty-acid amide hydrolase 10101
UDP-glucuronosyltransferase 1A80001
dual specificity protein phosphatase 30101
low molecular weight phosphotyrosine protein phosphatase isoform c0101
tyrosine-protein phosphatase non-receptor type 22 isoform 10101
streptokinase A precursor0011
cGMP-dependent 3',5'-cyclic phosphodiesterase0202
Bifunctional dihydrofolate reductase-thymidylate synthase0101
Solute carrier family 22 member 10101
Dihydrofolate reductase0404
Dihydrofolate reductase 0101
Estrogen receptor0011
Beta-hexosaminidase subunit alpha0102
Beta-hexosaminidase subunit beta0101
Dihydrofolate reductase0214
Bifunctional dihydrofolate reductase-thymidylate synthase0202
Dihydrofolate reductase0202
Substance-K receptor0101
Dihydrofolate reductase0101
Low molecular weight phosphotyrosine protein phosphatase0101
Dipeptidyl peptidase 40101
Pteridine reductase 10101
Bifunctional dihydrofolate reductase-thymidylate synthase0101
Bifunctional dihydrofolate reductase-thymidylate synthase0101
Trace amine-associated receptor 50011
Estrogen receptor beta0011
Bifunctional dihydrofolate reductase-thymidylate synthase0202
Multidrug and toxin extrusion protein 10101
Dihydrofolate reductase0101
PPM1D protein2002
Rap guanine nucleotide exchange factor 31001
Transcriptional activator protein LuxR0101
Free fatty acid receptor 30011
Orexin receptor type 10202
Orexin receptor type 20202
Orexin receptor type 10101
Orexin receptor type 20101
Substance-K receptor0101
Chain A, cAMP-specific 3',5'-cyclic phosphodiesterase 4B0101
Chain A, cAMP-specific 3',5'-cyclic phosphodiesterase 4B0101
Chain A, cAMP-specific 3',5'-cyclic phosphodiesterase 4B0101
Chain A, cAMP-specific 3',5'-cyclic phosphodiesterase 4B0101
Chain A, cAMP-specific 3',5'-cyclic phosphodiesterase 4B0101
Chain A, cAMP-specific 3',5'-cyclic phosphodiesterase 4B0101
Chain A, cAMP-specific 3',5'-cyclic phosphodiesterase 4D0101
Chain A, cAMP-specific 3',5'-cyclic phosphodiesterase 4D0101
Chain A, cAMP-specific 3',5'-cyclic phosphodiesterase 4D0101
Chain A, cAMP-specific 3',5'-cyclic phosphodiesterase 4D0101
Chain A, cAMP-specific 3',5'-cyclic phosphodiesterase 4B0101
Chain B, cAMP-specific 3',5'-cyclic phosphodiesterase 4B0101
Chain A, cGMP-specific 3',5'-cyclic phosphodiesterase0101
Chain A, cGMP-specific 3',5'-cyclic phosphodiesterase0101
Phosphodiesterase 0101
Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta0101
cGMP-specific 3',5'-cyclic phosphodiesterase0112
High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8A0101
High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A0101
High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8B0101
Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gamma0101
Rod cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha0101
Cystic fibrosis transmembrane conductance regulator0011
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A 0101
Potassium voltage-gated channel subfamily E member 10101
Rod cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha0101
Cone cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha'0101
Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gamma0101
Retinal cone rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gamma0101
Rod cGMP-specific 3',5'-cyclic phosphodiesterase subunit beta0101
Rod cGMP-specific 3',5'-cyclic phosphodiesterase subunit beta0101
Acetylcholinesterase0101
Cone cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha'0101
Potassium voltage-gated channel subfamily KQT member 10101
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A0101
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B0101
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B0101
Synaptic vesicular amine transporter0101
cAMP-specific 3',5'-cyclic phosphodiesterase 4B0101
cAMP-specific 3',5'-cyclic phosphodiesterase 4C0101
cAMP-specific 3',5'-cyclic phosphodiesterase 4D0101
cGMP-inhibited 3',5'-cyclic phosphodiesterase B0101
High affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A0101
Retinal cone rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gamma0101
cGMP-inhibited 3',5'-cyclic phosphodiesterase A0101
cGMP-specific 3',5'-cyclic phosphodiesterase0101
Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta0101
Dual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A0101
cAMP-specific 3',5'-cyclic phosphodiesterase 7B0101
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A0101
Nuclear receptor subfamily 2 group E member 10011
Chain A, Carbonic anhydrase 10101
Carbonic anhydrase 0001
Carbonic anhydrase 0101
Carbonic anhydrase 0101
Carbonic anhydrase 0101
Carbonic anhydrase0101
Carbonic anhydrase0101
Prolyl endopeptidase0101
Carbonic anhydrase-related protein 110001
Polyunsaturated fatty acid 5-lipoxygenase0101
Cytochrome P450 2C80101
Arachidonate 5-lipoxygenase-activating protein0101
Carbonic anhydrase 5A, mitochondrial0101
Carbonic anhydrase 20101
Carbonic anhydrase 0101
Beta-carbonic anhydrase 10101
Carbonic anhydrase 20101
Carbonic anhydrase, alpha family 0101
Carbonic anhydrase 0101
Delta carbonic anhydrase0101
Carbonic anhydrase 130101
Chain A, Trp Rna-binding Attenuation Protein0011
Chain K, Trp Rna-binding Attenuation Protein0011
Chain B, tryptophanyl-tRNA synthetase0011
Chain C, Tryptophanyl-tRNA synthetase II0011
thioredoxin glutathione reductase2002
Alkaline phosphatase, tissue-nonspecific isozyme0101
Stromelysin-10101
Intestinal-type alkaline phosphatase0101
Indoleamine 2,3-dioxygenase 10102
Tryptophan 2,3-dioxygenase0102
Tryprostatin B synthase0001
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase0011
Phospholipase A-2-activating protein0101
Prostaglandin E2 receptor EP1 subtype0011
Prostaglandin E2 receptor EP2 subtype0011
Prostacyclin receptor0011
Prostaglandin D2 receptor0011
Acetylcholine receptor subunit alpha0213
Neuronal acetylcholine receptor subunit alpha-30213
Acetylcholine receptor subunit gamma0213
Acetylcholine receptor subunit beta0213
Neuronal acetylcholine receptor subunit alpha-20101
Neuronal acetylcholine receptor subunit beta-30011
Neuronal acetylcholine receptor subunit beta-40213
Neuronal acetylcholine receptor subunit alpha-50011
Muscarinic acetylcholine receptor M40101
Neuronal acetylcholine receptor subunit alpha-60011
Acetylcholine receptor subunit delta0213
parathyroid hormone/parathyroid hormone-related peptide receptor precursor1001
Proprotein convertase subtilisin/kexin type 70101
Vitamin K epoxide reductase complex subunit 1-like protein 10101
Vitamin K epoxide reductase complex subunit 10101
Protease 0101
Vitamin K epoxide reductase complex subunit 1-like protein 10101
Vitamin K epoxide reductase complex subunit 1 0202
Aspartate aminotransferase, cytoplasmic0101
3-hydroxy-3-methylglutaryl-coenzyme A reductase 0101
Transporter0101
Sphingosine-1-phosphate lyase 10101
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]