Page last updated: 2024-09-28

Benign Infratentorial Neoplasms

Intracranial tumors originating in the region of the brain inferior to the TENTORIUM CEREBELLI, which contains the cerebellum, FOURTH VENTRICLE; CEREBELLOPONTINE ANGLE; BRAIN STEM, and related structures. Primary tumors of this region are more frequent in children, and may present with ATAXIA; CRANIAL NERVE DISEASES; vomiting; HEADACHE; HYDROCEPHALUS; or other signs of neurologic dysfunction. Relatively frequent histologic subtypes include TERATOMA; MEDULLOBLASTOMA; GLIOBLASTOMA; ASTROCYTOMA; EPENDYMOMA; CRANIOPHARYNGIOMA; and choroid plexus papilloma (PAPILLOMA, CHOROID PLEXUS).

Synonyms(11)

Synonym
Infratentorial Neoplasms, Benign
Infratentorial Neoplasms
Infratentorial Cancer
Infratentorial Neoplasms, Malignant
Malignant Infratentorial Neoplasms
Benign Infratentorial Neoplasms
Neoplasms, Infratentorial
Infratentorial Tumors
Posterior Fossa Tumors
Neoplasms, Posterior Fossa
Posterior Fossa Neoplasms

Research Excerpts

Overview

ExcerptReference
"Infratentorial tumors are relatively infrequent in dogs and a lack of data makes it difficult to offer prognostic information."( Benoit, J; Blackwood, L; Buchholz, J; Gonçalves, R; Maddox, TW; Treggiari, E, 2017)

Treatment

ExcerptReference
"Twenty-three consecutive patients with posterior fossa tumors underwent FIESTA sequence after contrast agent administration, and then displacement of the cranial nerve was evaluated."( Houkin, K; Koyanagi, I; Mikami, T; Minamida, Y; Nonaka, T; Yamaki, T, 2005)
"Twenty-two children with posterior fossa tumors who were treated surgically at Children's Hospital "Agia Sofia" were studied."( Alevizopoulos, GA; Alexiou, GA; Liakopoulou, M; Papakonstantinou, E; Pitsouni, D; Varela, M, 2014)

Research

Studies (74)

TimeframeStudies, This Condition (%)All Conditions %
pre-19902 (2.70)23.3326
1990's4 (5.41)12.5806
2000's26 (35.14)18.1394
2010's29 (39.19)28.8240
2020's13 (17.57)9.53
DrugIndicatedRelationship StrengthStudiesTrials
aminolevulinic acid0low20
choline0low50
salicylic acid0low10
creatine0low40
lactic acid0low20
dimethyl sulfoxide0low10
inositol0low20
homovanillic acid0low10
hydroxyindoleacetic acid0low10
amiodarone0low10
busulfan0low10
diazepam0low10
pentetic acid0low10
fentanyl0low10
lidocaine0low10
ifosfamide0low20
iohexol0low10
iothalamic acid0low10
isoflurane0low10
ketamine0low10
lomustine0low20
metronidazole0low10
midazolam0low10
apnea0low10
ondansetron0medium33
propofol0low30
sevoflurane0low10
temozolomide0low20
thiotepa0medium31
tranexamic acid0low10
prednisolone0low10
prednisone0low10
aspartic acid0low40
lysine0low20
carbostyril0low10
edetic acid0low10
methionine0low10
cytarabine0low10
methylprednisolone0low10
azacitidine0medium11
methoxyhydroxyphenylglycol0low10
vancomycin0low10
fluorescein0low30
mercury0low10
gadolinium0low20
camptothecin0low20
chlormerodrin0low10
bromocriptine0low10
etoposide0medium82
fomesafen0low20
topotecan0low10
temoporfin0low10
aripiprazole0low10
remifentanil0low20
irinotecan0low20
5-methylcytosine0low10
n-acetylaspartic acid0low40
5-hydroxymethylcytosine0low10
methotrexate0medium42
carboplatin0medium21
rocuronium0low10
dactinomycin0low10
melphalan0low10
isomethyleugenol0low10
phenylephrine hydrochloride0low20
morphine0medium21
talaporfin0low10
gadolinium dtpa0low20
phosphocreatine0low20
pirarubicin0low10
technetium tc 99m exametazime0low10
indocyanine green0low10
mesna0medium11
ro13-99040low10
piperidines0low20
levoleucovorin0medium11
dacarbazine0low10
eye0low10

Protein Targets (804)

ProteinPotency MeasurementsInhibition MeasurementsActivation MeasurementsDrugs
Chain A, Beta-lactamase5005
bromodomain adjacent to zinc finger domain 2B2002
geminin250025
Gamma-aminobutyric acid receptor subunit rho-10101
Glutamate receptor 10101
Glutamate receptor 20101
Glutamate receptor 30101
Glutamate receptor ionotropic, kainate 30101
Solute carrier family 15 member 10101
Glutamate receptor 40101
Solute carrier family 15 member 10101
Solute carrier family 15 member 20101
Chain A, TYROSYL-DNA PHOSPHODIESTERASE120012
acetylcholinesterase110011
phosphopantetheinyl transferase7007
hypoxia-inducible factor 1 alpha subunit130013
RAR-related orphan receptor gamma210021
SMAD family member 24004
ATAD5 protein, partial8008
Fumarate hydratase120012
USP1 protein, partial100010
NFKB1 protein, partial5005
PPM1D protein6006
SMAD family member 34004
TDP1 protein290029
Thrombopoietin3003
AR protein260026
caspase 7, apoptosis-related cysteine protease6006
aldehyde dehydrogenase 1 family, member A1160016
hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)8008
thyroid stimulating hormone receptor9009
estrogen receptor 2 (ER beta)140014
nuclear receptor subfamily 1, group I, member 3160016
progesterone receptor190019
EWS/FLI fusion protein170017
glucocorticoid receptor [Homo sapiens]190019
retinoic acid nuclear receptor alpha variant 1200020
retinoid X nuclear receptor alpha170017
estrogen-related nuclear receptor alpha280028
farnesoid X nuclear receptor110011
pregnane X nuclear receptor230023
estrogen nuclear receptor alpha290029
G120012
cytochrome P450 2D69009
polyprotein120012
peroxisome proliferator-activated receptor delta130013
peroxisome proliferator activated receptor gamma170017
caspase-36006
euchromatic histone-lysine N-methyltransferase 2240024
thyroid stimulating hormone receptor110011
v-jun sarcoma virus 17 oncogene homolog (avian)130013
Histone H2A.x130013
cytochrome P450 2D6 isoform 11001
cellular tumor antigen p53 isoform a5005
cytochrome P450 2C9 precursor2002
D(1A) dopamine receptor5005
chromobox protein homolog 1140014
thyroid hormone receptor beta isoform a4004
potassium voltage-gated channel subfamily H member 2 isoform d6006
thyroid hormone receptor beta isoform 2200020
heat shock protein beta-17007
huntingtin isoform 24004
mitogen-activated protein kinase 13003
flap endonuclease 14004
serine/threonine-protein kinase mTOR isoform 15005
nuclear factor erythroid 2-related factor 2 isoform 1190019
peptidyl-prolyl cis-trans isomerase NIMA-interacting 15005
urokinase-type plasminogen activator precursor5005
plasminogen precursor5005
urokinase plasminogen activator surface receptor precursor5005
nuclear receptor ROR-gamma isoform 16006
peripheral myelin protein 22120012
survival motor neuron protein isoform d8008
cytochrome P450 3A4 isoform 17007
muscarinic acetylcholine receptor M16006
lethal factor (plasmid)4004
lamin isoform A-delta10220022
Gamma-aminobutyric acid receptor subunit pi76215
Polyunsaturated fatty acid lipoxygenase ALOX15B3003
ATP-binding cassette sub-family C member 3023023
Multidrug resistance-associated protein 4023024
Voltage-dependent L-type calcium channel subunit alpha-1C0101
Solute carrier organic anion transporter family member 1A40101
Voltage-dependent L-type calcium channel subunit alpha-1F0303
5-hydroxytryptamine receptor 40606
Lysine-specific demethylase PHF20101
Bile salt export pump026026
Interferon beta170017
HLA class I histocompatibility antigen, B alpha chain 120012
Thyroid hormone receptor alpha0101
Receptor tyrosine-protein kinase erbB-20202
Cellular tumor antigen p53240024
Integrin beta-35207
Tyrosine-protein kinase Fyn0202
ATP-dependent translocase ABCB10505
Aldo-keto reductase family 1 member B10404
Muscarinic acetylcholine receptor M20202
Muscarinic acetylcholine receptor M40404
ATP-dependent translocase ABCB1010116
Integrin alpha-IIb5106
Beta-1 adrenergic receptor0404
Muscarinic acetylcholine receptor M50202
Alpha-2A adrenergic receptor0516
Adenosine receptor A30303
Cytochrome P450 2C80101
Thyroid hormone receptor alpha0101
Thyroid hormone receptor beta0101
Muscarinic acetylcholine receptor M10202
Beta-3 adrenergic receptor0202
D(2) dopamine receptor08210
Androgen receptor0707
Gamma-aminobutyric acid receptor subunit beta-176215
Alpha-1B adrenergic receptor0505
Lethal factor0101
Alpha-2B adrenergic receptor0404
Thyroid hormone receptor beta0101
Gamma-aminobutyric acid receptor subunit delta76215
Gamma-aminobutyric acid receptor subunit gamma-276215
Gamma-aminobutyric acid receptor subunit alpha-576215
Gamma-aminobutyric acid receptor subunit alpha-376215
Muscarinic acetylcholine receptor M30303
ATP-dependent translocase ABCB10606
Substance-K receptor0404
D(1A) dopamine receptor0505
D(4) dopamine receptor0404
Gamma-aminobutyric acid receptor subunit gamma-176215
Gamma-aminobutyric acid receptor subunit alpha-276215
Carnitine O-palmitoyltransferase 2, mitochondrial0101
Sodium-dependent noradrenaline transporter 0404
Histamine H2 receptor0202
Endothelin-1 receptor0202
5-hydroxytryptamine receptor 2A0718
5-hydroxytryptamine receptor 2C0819
Gamma-aminobutyric acid receptor subunit alpha-476215
Gamma-aminobutyric acid receptor subunit gamma-376215
Lysine-specific demethylase 5A0101
Gamma-aminobutyric acid receptor subunit alpha-676215
B2 bradykinin receptor0202
Sodium-dependent serotonin transporter0303
Melanocortin receptor 40202
C-8 sterol isomerase0101
Melanocortin receptor 50404
Mu-type opioid receptor0629
D(3) dopamine receptor0617
Sodium channel protein type 1 subunit alpha0101
Sodium channel protein type 4 subunit alpha0303
Squalene synthase0101
Delta-type opioid receptor08110
Kappa-type opioid receptor0618
5-hydroxytryptamine receptor 2B011011
C-C chemokine receptor type 20202
Melanocortin receptor 30202
Alpha-1A adrenergic receptor0505
Histamine H2 receptor4004
D(1A) dopamine receptor4004
5-hydroxytryptamine receptor 60506
Carnitine O-palmitoyltransferase 1, liver isoform0101
C-C chemokine receptor type 40202
Spike glycoprotein120012
Gamma-aminobutyric acid receptor subunit alpha-176215
Gamma-aminobutyric acid receptor subunit beta-376215
Gamma-aminobutyric acid receptor subunit beta-276215
Sodium channel protein type 7 subunit alpha0101
Voltage-dependent L-type calcium channel subunit alpha-1D 0303
Sodium-dependent dopamine transporter 0202
Potassium voltage-gated channel subfamily H member 20707
Voltage-dependent L-type calcium channel subunit alpha-1S0303
Voltage-dependent L-type calcium channel subunit alpha-1C0303
Sodium channel protein type 5 subunit alpha0202
Squalene monooxygenase0101
3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase0101
Sodium channel protein type 9 subunit alpha0202
Lysine-specific demethylase 7A0101
GABA theta subunit76215
Carnitine O-palmitoyltransferase 1, muscle isoform0101
Inositol hexakisphosphate kinase 1120012
Canalicular multispecific organic anion transporter 1023024
Sodium channel protein type 2 subunit alpha0101
Ataxin-2140014
Sigma non-opioid intracellular receptor 10505
Gamma-aminobutyric acid receptor subunit epsilon76215
NAD-dependent protein deacetylase sirtuin-3, mitochondrial0011
Sodium channel protein type 3 subunit alpha0202
Sodium channel protein type 11 subunit alpha0101
Histone lysine demethylase PHF80101
Sodium channel protein type 8 subunit alpha0101
Sodium channel protein type 10 subunit alpha0101
cytochrome P450 2C9, partial120012
ATP-dependent phosphofructokinase110011
thioredoxin reductase140014
Microtubule-associated protein tau7007
arylsulfatase A6006
Bloom syndrome protein isoform 1100010
neuropeptide S receptor isoform A3003
Chain A, JmjC domain-containing histone demethylation protein 3A2002
5-hydroxytryptamine receptor 3E0214
GLI family zinc finger 3180018
67.9K protein9009
vitamin D (1,25- dihydroxyvitamin D3) receptor150015
heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)2002
nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105), isoform CRA_a8008
lysosomal alpha-glucosidase preproprotein4004
mu-type opioid receptor isoform MOR-10022
nuclear factor erythroid 2-related factor 2 isoform 29009
transcriptional regulator ERG isoform 33003
histone acetyltransferase KAT2A isoform 18008
5-hydroxytryptamine receptor 2A0022
Solute carrier family 22 member 20405
5-hydroxytryptamine receptor 3A0112
Voltage-dependent calcium channel gamma-2 subunit110011
5-hydroxytryptamine receptor 3B0214
Cytochrome P450 3A409110
5-hydroxytryptamine receptor 1A0314
5-hydroxytryptamine receptor 2C0304
Neuronal acetylcholine receptor subunit alpha-42305
Neuronal acetylcholine receptor subunit beta-22204
5-hydroxytryptamine receptor 2A0303
Alpha-2C adrenergic receptor0505
D0303
5-hydroxytryptamine receptor 1A0617
Glutamate receptor 2110011
D(1B) dopamine receptor0101
Alpha-1D adrenergic receptor0303
Alpha-1D adrenergic receptor0303
D(4) dopamine receptor0303
Histamine H1 receptor0112
5-hydroxytryptamine receptor 7 0202
5-hydroxytryptamine receptor 70202
Alpha-1A adrenergic receptor0202
Histamine H1 receptor0303
Alpha-1B adrenergic receptor0101
5-hydroxytryptamine receptor 3A0315
3-hydroxy-3-methylglutaryl-coenzyme A reductase 0101
D(2) dopamine receptor0314
Inositol monophosphatase 13003
5-hydroxytryptamine receptor 3D0214
Multidrug and toxin extrusion protein 20404
5-hydroxytryptamine receptor 3C0214
Multidrug and toxin extrusion protein 10606
Histamine H3 receptor0101
Chain A, MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASE110011
Chain A, Ferritin light chain6006
cytochrome P450 2C19 precursor4004
Metabotropic glutamate receptor 60011
Excitatory amino acid transporter 40101
Glutamate transporter homolog0011
Carbonic anhydrase 10506
Carbonic anhydrase 20517
N(4)-(beta-N-acetylglucosaminyl)-L-asparaginase0101
5-hydroxytryptamine receptor 1D0001
Glutamate receptor ionotropic, NMDA 1 0304
Excitatory amino acid transporter 10101
Excitatory amino acid transporter 20101
Excitatory amino acid transporter 30101
Glutamate receptor ionotropic, NMDA 2A 0304
Glutamate receptor ionotropic, NMDA 2B0304
Glutamate receptor ionotropic, NMDA 2C0405
Metabotropic glutamate receptor 10011
Metabotropic glutamate receptor 20011
Carbonic anhydrase-like protein, putative0001
Glutamate receptor ionotropic, NMDA 2D0304
Glutamate receptor ionotropic, NMDA 3B0304
Carbonic anhydrase 40001
Glutamate receptor ionotropic, NMDA 3A0304
interleukin 83003
glp-1 receptor, partial6006
pregnane X receptor3003
Smad33003
cytochrome P450 family 3 subfamily A polypeptide 4190019
Parkin1001
IDH17007
aryl hydrocarbon receptor8008
cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a120012
activating transcription factor 68008
peripheral myelin protein 22 isoform 14004
hemoglobin subunit beta3003
ras-related protein Rab-9A2002
DNA (cytosine-5)-methyltransferase 10101
Adenosine receptor A2a0101
Adenosine receptor A10101
Nuclear receptor ROR-gamma4004
Histone-lysine N-methyltransferase EHMT20101
ATPase family AAA domain-containing protein 5120012
Genome polyprotein 0112
dopamine D1 receptor2002
GLS protein8008
regulator of G-protein signaling 45005
vitamin D3 receptor isoform VDRA8008
D(3) dopamine receptor0202
Alpha-2B adrenergic receptor0202
Alpha-2C adrenergic receptor0202
Alpha-2A adrenergic receptor0303
D(1B) dopamine receptor0202
5-hydroxytryptamine receptor 1B0303
Alpha-synuclein0101
Chain A, 2-oxoglutarate Oxygenase8008
15-lipoxygenase, partial8008
apical membrane antigen 1, AMA11001
ubiquitin carboxyl-terminal hydrolase 2 isoform a1001
Matrix metalloproteinase-90202
Disintegrin and metalloproteinase domain-containing protein 171001
Chain A, HADH2 protein4004
Chain B, HADH2 protein4004
Chain A, Cruzipain2002
DNA topoisomerase 0101
glucocerebrosidase2002
putative alpha-glucosidase1001
alpha-galactosidase3003
15-hydroxyprostaglandin dehydrogenase [NAD(+)] isoform 16006
eukaryotic translation initiation factor 2-alpha kinase 3 isoform 1 precursor0011
DNA polymerase iota isoform a (long)7007
M-phase phosphoprotein 85005
muscleblind-like protein 1 isoform 15005
relaxin receptor 1 isoform 11001
Telomerase reverse transcriptase0101
Serine/threonine-protein kinase Chk10011
Histone deacetylase 30101
Type-2 restriction enzyme ScaI0101
Deoxyribonuclease-2-alpha0101
Tyrosyl-DNA phosphodiesterase 20101
Deoxyribonuclease-10101
Type-2 restriction enzyme PstI0101
Type-2 restriction enzyme EcoRI0101
Prothrombin0002
DNA ligase0101
Heterogeneous nuclear ribonucleoprotein A10011
DNA topoisomerase 103313
DNA topoisomerase 2-alpha0319
Type-2 restriction enzyme BamHI0101
Somatostatin receptor type 10101
Somatostatin receptor type 20101
Somatostatin receptor type 40101
Somatostatin receptor type 30101
Somatostatin receptor type 50101
Type-2 restriction enzyme HindIII0101
Histone deacetylase 40101
Ribonuclease pancreatic0101
DNA topoisomerase 2-beta02110
DNA topoisomerase 10203
Histone deacetylase 10101
DNA topoisomerase 10101
Integrase 0202
Histone deacetylase 70101
Histone deacetylase 20101
DNA topoisomerase type IB small subunit 0011
Polyamine deacetylase HDAC100101
Histone deacetylase 11 0101
Histone deacetylase 80101
Tyrosyl-DNA phosphodiesterase 10101
Histone deacetylase 60101
Histone deacetylase 90101
Histone deacetylase 50101
Chain A, Putative fructose-1,6-bisphosphate aldolase4004
histone-lysine N-methyltransferase 2A isoform 2 precursor2002
DNA polymerase kappa isoform 16006
Chain A, serum paraoxonase0101
Carbonic anhydrase 120303
Carbonic anhydrase 30202
Neutrophil cytosol factor 10101
Carbonic anhydrase 40202
Carbonic anhydrase 60202
Carbonic anhydrase 5A, mitochondrial0202
Carbonic anhydrase 70202
Carbonic anhydrase 90303
Carbonic anhydrase 130101
Poly [ADP-ribose] polymerase tankyrase-20101
Carbonic anhydrase 140202
Carbonic anhydrase 5B, mitochondrial0202
Chain A, Acetylcholinesterase0011
Chain A, Acetylcholinesterase0011
Chain A, Acetylcholinesterase0011
Chain A, Acetylcholinesterase0011
Chain A, Acetylcholinesterase0011
Chain A, Acetylcholinesterase0011
Chain A, Acetylcholinesterase0011
Chain A, Putative Glycine Betaine-binding Abc Transporter Protein0011
Chain A, PUTATIVE GLYCINE BETAINE-BINDING ABC TRANSPORTER PROTEIN0011
Chain A, Glycine betaine/carnitine/choline-binding protein0011
Chain A, Glycine betaine/carnitine/choline-binding protein0011
Chain A, Glycine betaine/carnitine/choline-binding protein0011
Chain A, Glycine betaine/carnitine/choline-binding protein0011
Chain A, Choline-binding protein0011
Solute carrier family 22 member 10102
Solute carrier family 22 member 1 0506
Solute carrier family 22 member 20101
Neuronal acetylcholine receptor subunit alpha-30101
Neuronal acetylcholine receptor subunit alpha-20101
Neuronal acetylcholine receptor subunit beta-30101
Neuronal acetylcholine receptor subunit beta-40101
Neuronal acetylcholine receptor subunit alpha-50101
Acetylcholinesterase0404
Sodium- and chloride-dependent creatine transporter 10101
Choline O-acetyltransferase 0102
Neuronal acetylcholine receptor subunit alpha-60101
Neuronal acetylcholine receptor subunit alpha-90101
Neuronal acetylcholine receptor subunit alpha-70303
Solute carrier family 22 member 10102
High affinity choline transporter 10101
Neuronal acetylcholine receptor subunit alpha-100101
Solute carrier family 22 member 20102
Sodium- and chloride-dependent creatine transporter 10101
Proton-coupled amino acid transporter 10101
endonuclease IV3003
LMP1 [Human herpesvirus 4]0003
nuclear receptor coactivator 1 isoform 1 [Homo sapiens]0303
transactivating tegument protein VP16 [Human herpesvirus 1]0303
nuclear receptor coactivator 3 isoform a0303
Thymidine kinase 2, mitochondrial0101
Thymidine kinase, cytosolic0101
Thymidine kinase0101
Thymidylate synthase0203
Thymidine kinase0101
Deoxycytidine kinase0001
Probable deoxycytidylate deaminase0001
Cytidine deaminase0102
E3 ubiquitin-protein ligase Mdm20101
Enoyl-[acyl-carrier-protein] reductase [NADH] 0101
Thymidine kinase0101
Deoxynucleoside kinase0101
Isocitrate lyase0101
Chain A, ATP-DEPENDENT DNA HELICASE Q12002
RAD510101
Caspase-72002
caspase-32002
caspase-1 isoform alpha precursor2002
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 10101
Caspase-72002
Growth factor receptor-bound protein 20101
Pantothenate synthetase0101
Discoidin domain-containing receptor 20101
Growth factor receptor-bound protein 2 0101
Reverse transcriptase/RNaseH 0101
Peptide-N(4)-(N-acetyl-beta-glucosaminyl)asparagine amidase0011
Gamma-aminobutyric acid 0101
Gamma-aminobutyric acid receptor subunit pi0202
Gamma-aminobutyric acid receptor subunit delta0202
Fatty acid-binding protein, liver0202
Alpha-1-acid glycoprotein 10001
Albumin0124
Albumin0011
Gamma-aminobutyric acid receptor subunit alpha-10203
Gamma-aminobutyric acid receptor subunit beta-10203
Gamma-aminobutyric acid receptor subunit alpha-20203
Gamma-aminobutyric acid receptor subunit alpha-30203
Gamma-aminobutyric acid receptor subunit alpha-10336
Translocator protein0225
Gamma-aminobutyric acid receptor subunit alpha-60101
Gamma-aminobutyric acid receptor subunit beta-10213
Gamma-aminobutyric acid receptor subunit gamma-20325
Gamma-aminobutyric acid receptor subunit alpha-40203
Gamma-aminobutyric acid receptor subunit gamma-20203
Gamma-aminobutyric acid receptor subunit gamma-20101
Gamma-aminobutyric acid receptor subunit delta0101
Gamma-aminobutyric acid receptor subunit alpha-20101
Gamma-aminobutyric acid receptor subunit alpha-30101
Gamma-aminobutyric acid receptor subunit gamma-30101
Gamma-aminobutyric acid receptor subunit beta-30325
Translocator protein0101
Translocator protein0101
Cholecystokinin receptor type A0202
Gastrin/cholecystokinin type B receptor0202
Gamma-aminobutyric acid receptor subunit alpha-50235
Gamma-aminobutyric acid receptor subunit alpha-30224
Gamma-aminobutyric acid receptor subunit alpha-20224
Gamma-aminobutyric acid receptor subunit beta-20224
Gamma-aminobutyric acid receptor subunit alpha-40213
Gamma-aminobutyric acid receptor subunit beta-10101
Gamma-aminobutyric acid receptor subunit alpha-10101
Gamma-aminobutyric acid receptor subunit beta-30101
Gamma-aminobutyric acid receptor subunit epsilon0202
Gamma-aminobutyric acid receptor subunit alpha-60213
Gamma-aminobutyric acid receptor subunit alpha-50101
Gamma-aminobutyric acid receptor subunit gamma-10202
Gamma-aminobutyric acid receptor subunit pi0101
Sphingosine-1-phosphate lyase 10101
Gamma-aminobutyric acid receptor subunit gamma-30202
Gamma-aminobutyric acid receptor subunit alpha-40101
Gamma-aminobutyric acid receptor subunit theta0101
Gamma-aminobutyric acid receptor subunit gamma-10101
Gamma-aminobutyric acid receptor subunit theta0202
Cereblon isoform 40202
Insulin-like growth factor-binding protein 50011
Protein cereblon0202
Eyes absent homolog 20101
Amyloid-beta precursor protein0202
Angiotensin-converting enzyme 0101
Metallo-beta-lactamase VIM-130101
Beta-lactamase 0101
Beta-lactamase 0101
Beta-lactamase VIM-1 0101
Regulatory protein E20011
Cytochrome P450 2C9 0202
Polyunsaturated fatty acid lipoxygenase ALOX150202
DNA topoisomerase 20001
UDP-glucuronosyltransferase 1A1 0203
Serum paraoxonase/arylesterase 10303
Caspase-30101
DNA topoisomerase 2-alpha 0001
Tubulin beta-2B chain0114
Similar to alpha-tubulin isoform 1 0114
Similar to alpha-tubulin isoform 1 0103
Solute carrier organic anion transporter family member 1B30405
Luciferase7007
Nuclear receptor subfamily 1 group I member 20022
Amine oxidase [flavin-containing] A0101
Amine oxidase [flavin-containing] B0101
Delta-type opioid receptor0304
Delta-type opioid receptor0618
Mu-type opioid receptor07212
Kappa-type opioid receptor0517
Kappa-type opioid receptor0404
Mu-type opioid receptor0316
Mu-type opioid receptor0404
Sigma non-opioid intracellular receptor 10303
Sigma non-opioid intracellular receptor 10202
thyrotropin-releasing hormone receptor1001
ClpP2002
Solute carrier family 22 member 80001
hypothetical protein, conserved1001
Uracil nucleotide/cysteinyl leukotriene receptor0101
GALC protein4004
Chain B, Pulmonary surfactant-associated protein D0101
Chain A, Pulmonary surfactant-associated protein D0101
parathyroid hormone/parathyroid hormone-related peptide receptor precursor1001
TAR DNA-binding protein 434004
Sodium/myo-inositol cotransporter 20101
Chain A, Acetylcholinesterase0101
interferon gamma precursor0001
Solute carrier family 22 member 30202
Interstitial collagenase0101
Acetylcholinesterase0101
Liver carboxylesterase 10001
Neuronal acetylcholine receptor subunit beta-20303
Neuronal acetylcholine receptor subunit alpha-70101
Glutamate receptor ionotropic, NMDA 2D0101
Acetylcholinesterase0202
Glutamate receptor ionotropic, NMDA 3B0101
Rap guanine nucleotide exchange factor 31001
Cholinesterase0101
Glutamate receptor ionotropic, NMDA 10202
Glutamate receptor ionotropic, NMDA 2A0202
Glutamate receptor ionotropic, NMDA 2B0202
Glutamate receptor ionotropic, NMDA 2C0101
Glutamate receptor ionotropic, NMDA 3A0101
Potassium channel subfamily K member 30101
Potassium channel subfamily K member 20101
Sodium channel protein type 1 subunit alpha0101
Sodium channel protein type 2 subunit alpha0101
Sodium channel protein type 3 subunit alpha0101
Potassium voltage-gated channel subfamily A member 50101
Potassium voltage-gated channel subfamily D member 20101
Potassium channel subfamily K member 180101
Chain A, Ribulose-1,5 bisphosphate carboxylase/oxygenase large subunit N-methyltransferase, chloroplast0101
Chain A, Ribulose-1,5 bisphosphate carboxylase/oxygenase large subunit N-methyltransferase, chloroplast0101
Glutathione reductase, mitochondrial0202
Cationic amino acid transporter 30101
thioredoxin glutathione reductase2002
importin subunit beta-1 isoform 12002
snurportin-12002
Large neutral amino acids transporter small subunit 1 0101
Chain A, Methionyl-tRNA synthetase0011
Chain A, Methionyl-tRNA synthetase0011
Chain A, Aminopeptidase0101
Chain A, Methionine aminopeptidase0101
S-ribosylhomocysteine lyase0101
Adenylate cyclase type 50001
S-adenosylmethionine synthase isoform type-10001
S-adenosylmethionine synthase isoform type-20001
Fatty acid synthase0101
Large neutral amino acids transporter small subunit 10101
Chain B, DIHYDROFOLATE REDUCTASE0011
Chain B, DIHYDROFOLATE REDUCTASE0011
Chain B, DIHYDROFOLATE REDUCTASE0011
acid sphingomyelinase1001
Thymidylate synthase 0101
Thymidylate synthase 0101
polyunsaturated fatty acid lipoxygenase ALOX121001
DNA polymerase beta1001
DNA polymerase eta isoform 11001
Toll-like receptor 40101
Fatty-acid amide hydrolase 10101
Bile salt export pump0202
ATP-binding cassette sub-family C member 30102
Dihydrofolate reductase0203
Dihydrofolate reductase0203
Dihydrofolate reductase 0101
Dihydrofolate reductase0101
Dihydrofolate reductase0101
Dihydrofolate reductase0203
Thymidylate synthase0101
Tyrosine-protein kinase ABL10213
Thymidylate synthase0202
Bifunctional dihydrofolate reductase-thymidylate synthase0101
High mobility group protein B10022
Dihydrofolate reductase0101
Thymidylate synthase0101
Dihydrofolate reductase0224
Glucose-6-phosphate 1-dehydrogenase0101
Bifunctional dihydrofolate reductase-thymidylate synthase0101
Folate receptor beta0101
Cytochrome P450 11B1, mitochondrial 0101
Folate receptor alpha0101
Dihydrofolate reductase0202
Histidine decarboxylase0112
Trifunctional purine biosynthetic protein adenosine-30101
Cyclin-dependent kinase 20011
Bifunctional purine biosynthesis protein ATIC0202
Multidrug resistance-associated protein 1 0001
Reduced folate transporter0202
Folylpolyglutamate synthase, mitochondrial0103
6-phosphogluconate dehydrogenase, decarboxylating0101
Solute carrier organic anion transporter family member 1A30001
Dihydrofolate reductase0101
Pteridine reductase 10101
Folylpolyglutamate synthase, mitochondrial0103
Bifunctional dihydrofolate reductase-thymidylate synthase0101
Bifunctional dihydrofolate reductase-thymidylate synthase0101
Solute carrier family 22 member 60102
Canalicular multispecific organic anion transporter 10102
Trifunctional purine biosynthetic protein adenosine-30101
Solute carrier family 22 member 200303
Dihydrofolate reductase 0101
Solute carrier family 22 member 80102
Solute carrier family 22 member 60303
Dihydrofolate reductase0101
ATP-binding cassette sub-family C member 110001
Proton-coupled folate transporter0101
Multidrug resistance associated protein0102
Solute carrier family 22 member 110001
Protein-arginine deiminase type-40101
Broad substrate specificity ATP-binding cassette transporter ABCG20102
nonstructural protein 12002
nuclear receptor subfamily 1, group I, member 24004
Glucocorticoid receptor06213
Glycine receptor subunit alpha-10606
Glycine receptor subunit beta0606
Glycine receptor subunit alpha-20606
Glycine receptor subunit alpha-30606
Nuclear receptor subfamily 1 group I member 20011
Thioredoxin reductase 0101
Flavodoxin0001
Lanosterol 14-alpha demethylase0101
UDP-glucuronosyltransferase 2B70202
UDP-glucuronosyltransferase 1-60202
UDP-glucuronosyltransferase 1A40202
UDP-glucuronosyltransferase 2B10 0202
Opioid receptor, delta 1b 0101
Opioid receptor homologue0101
Acyl-CoA desaturase 10101
Muscarinic acetylcholine receptor M10202
Muscarinic acetylcholine receptor M30202
Muscarinic acetylcholine receptor M40101
Muscarinic acetylcholine receptor M50101
Muscarinic acetylcholine receptor M20202
Proteinase-activated receptor 10112
Sodium-dependent serotonin transporter0202
Kappa-type opioid receptor0214
UDP-glucuronosyltransferase 1A30001
Nociceptin receptor0101
5-hydroxytryptamine receptor 70202
Mu-type opioid receptor0101
Beta-2 adrenergic receptor0101
Mas-related G-protein coupled receptor member X20011
Mu-type opioid receptor0101
Rap guanine nucleotide exchange factor 41001
Beta-2 adrenergic receptor0101
Beta-1 adrenergic receptor0101
Voltage-dependent L-type calcium channel subunit alpha-1C0101
Interleukin-6 receptor subunit alpha0101
5-hydroxytryptamine receptor 3A0101
Beta-3 adrenergic receptor0101
Voltage-dependent L-type calcium channel subunit alpha-1D0101
5-hydroxytryptamine receptor 1D0101
Neuronal acetylcholine receptor subunit beta-40101
5-hydroxytryptamine receptor 1F0101
5-hydroxytryptamine receptor 2B0101
5-hydroxytryptamine receptor 60101
Histamine H1 receptor0101
Neuronal acetylcholine receptor subunit alpha-30101
5-hydroxytryptamine receptor 5A0101
5-hydroxytryptamine receptor 5B0101
5-hydroxytryptamine receptor 3A0213
Neuronal acetylcholine receptor subunit alpha-40202
Neuronal acetylcholine receptor subunit alpha-70101
Thyrotropin-releasing hormone receptor0101
Voltage-dependent L-type calcium channel subunit alpha-1S0101
Glycine receptor subunit alpha-40101
5-hydroxytryptamine receptor 4 0101
5-hydroxytryptamine receptor 3B0101
5-hydroxytryptamine receptor 3B0213
Histamine H3 receptor0101
Leukotriene B4 receptor 10101
Nischarin0101
Genome polyprotein 0101
NPC intracellular cholesterol transporter 1 precursor1001
Epidermal growth factor receptor0101
Tubulin alpha-1A chain0012
Tubulin beta chain0011
Tubulin beta-4A chain0113
Integrin alpha-V 0101
Tubulin beta chain0113
60 kDa chaperonin0101
Tubulin alpha-3C chain0113
Botulinum neurotoxin type A 0101
Apoptosis regulator Bcl-20101
60 kDa heat shock protein, mitochondrial0202
Fibroblast growth factor receptor 10101
Proto-oncogene tyrosine-protein kinase Src0101
Cholecystokinin receptor type A0202
10 kDa heat shock protein, mitochondrial0202
Tubulin alpha-1B chain0113
Tubulin alpha-4A chain0113
Tubulin beta-4B chain0113
Bcl-2-like protein 10101
Tyrosine-protein kinase Mer0101
Tubulin beta-3 chain0214
Tubulin beta-2A chain0113
Thiosulfate sulfurtransferase0202
Beta-tubulin 0101
Tubulin beta-8 chain0113
60 kDa chaperonin 0202
Tubulin alpha-3E chain0113
Tubulin alpha-1A chain0113
10 kDa chaperonin 0202
Tubulin alpha-1C chain0113
Tubulin beta-6 chain0113
Tubulin beta-2B chain0113
Tubulin beta-1 chain0113
Nucleotide-binding oligomerization domain-containing protein 20101
Solute carrier organic anion transporter family member 1B10202
beta-2 adrenergic receptor1001
Vpr1001
histone deacetylase 9 isoform 32002
luciferase0001
Estrogen receptor0202
Progesterone receptor0203
Glucocorticoid receptor0112
Glucocorticoid receptor0011
Corticosteroid-binding globulin0101
Mineralocorticoid receptor 0213
Androgen receptor0202
Glutamine synthetase0011
Prostaglandin G/H synthase 20202
Nociceptin receptor0011
Cytochrome P450 2J20101
Estrogen receptor beta0202
Chain A, Ferritin light chain0011
Chain A, Ferritin light chain0011
Chain A, Ferritin light chain0011
Chain A, Ferritin light chain0011
Chain A, Ferritin light chain0011
Chain A, Ferritin light chain0011
Chain A, Ferritin light chain0011
Fatty-acid amide hydrolase 10101
UDP-glucuronosyltransferase 1A90001
Prostaglandin G/H synthase 10202
Sodium- and chloride-dependent GABA transporter 10101
Sodium- and chloride-dependent GABA transporter 20101
Sodium- and chloride-dependent GABA transporter 30101
Sodium- and chloride-dependent betaine transporter0101
Fatty-acid amide hydrolase 10101
UDP-glucuronosyltransferase 1A80001
chaperonin-containing TCP-1 beta subunit homolog1001
Estrogen receptor beta0001
Inhibitor of nuclear factor kappa-B kinase subunit beta0001
Solute carrier family 22 member 60101
Polyphenol oxidase 20102
5'-AMP-activated protein kinase subunit beta-20001
Polymerase acidic protein0011
Stromelysin-10011
Tyrosine-protein phosphatase YopH0101
Aldo-keto reductase family 1 member B10101
Prolyl 4-hydroxylase subunit alpha-10101
Tyrosine-protein phosphatase non-receptor type 10103
Estrogen receptor0001
Cystathionine gamma-lyase0101
5'-AMP-activated protein kinase subunit gamma-10001
5'-AMP-activated protein kinase catalytic subunit alpha-20001
Xanthine dehydrogenase/oxidase0101
5'-AMP-activated protein kinase catalytic subunit alpha-10001
Carbonic anhydrase0101
Solute carrier family 22 member 70001
Nicotinate phosphoribosyltransferase0101
Ubiquitin-like domain-containing CTD phosphatase 10101
Carbonic anhydrase 150101
Carbonic anhydrase 130101
5'-AMP-activated protein kinase subunit gamma-30001
5'-AMP-activated protein kinase subunit gamma-20001
5'-AMP-activated protein kinase subunit beta-10001
polyadenylate-binding protein 10101
Tyrosine-protein kinase ABL20101
serine/threonine-protein kinase PLK11001
Cytochrome P450 2B10101
Cytochrome P450 2B60101
NPYLR7B0011
tyrosine-protein kinase Yes1001
Hypoxia-inducible factor 1-alpha0112
Endothelial PAS domain-containing protein 10011
Chain A, PLASMINOGEN0011
Chain A, PLASMINOGEN0011
Plasminogen0213
Urokinase-type plasminogen activator0101
D-alanyl-D-alanine dipeptidase0101
Transporter0101
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]