Page last updated: 2024-09-28

Avian Hypersensitivity Pneumonitis

A form of alveolitis or pneumonitis due to an acquired hypersensitivity to inhaled avian antigens, usually proteins in the dust of bird feathers and droppings.

Synonyms(7)

Synonym
Avian Hypersensitivity Pneumonitis
Bird Fancier's Lung
Pigeon Breeder's Lung
Pneumonitis, Hypersensitivity, Avian
Hypersensitivity Pneumonitis, Avian
Pneumonitis, Avian Hypersensitivity
Budgerigar Fancier's Lung

Research Excerpts

Overview

ExcerptReference
"Bird fancier's lung is a typical manifestation of extrinsic allergic alveolitis."( Berzon, R; Liebetrau, G; Pielesch, W; Riedel, E, 1987)

Research

Studies (74)

TimeframeStudies, This Condition (%)All Conditions %
pre-199027 (36.49)23.3326
1990's22 (29.73)12.5806
2000's15 (20.27)18.1394
2010's6 (8.11)28.8240
2020's4 (5.41)9.53
DrugIndicatedRelationship StrengthStudiesTrials
carbon monoxide0low50
citric acid, anhydrous0low10
urea0low40
acetaminophen0low10
amiodarone0low10
cimetidine0low10
pentetic acid0low20
prednisolone0low110
hydroxyproline0low10
penicillamine0low10
prednisone0low60
edetic acid0low10
egtazic acid0low10
phencyclidine0low120
methylprednisolone0low10
reticulin0low10
technetium0low10
trolamine salicylate0low10
technetium tc 99m pentetate0low10
cotinine0low10
sodium dodecyl sulfate0low20
pulmicort0low10
(dtpa-phe(1))-octreotide0low10
methylcellulose0low30
transforming growth factor beta0low10
allopurinol0low10
concanavalin a0low20

Protein Targets (453)

ProteinPotency MeasurementsInhibition MeasurementsActivation MeasurementsDrugs
IDH14004
chromobox protein homolog 15005
geminin9009
RAR-related orphan receptor gamma120012
ATAD5 protein, partial4004
GLS protein2002
Microtubule-associated protein tau2002
Smad32002
aldehyde dehydrogenase 1 family, member A16006
thyroid stimulating hormone receptor7007
nuclear receptor subfamily 1, group I, member 37007
progesterone receptor9009
EWS/FLI fusion protein2002
retinoic acid nuclear receptor alpha variant 19009
retinoid X nuclear receptor alpha8008
estrogen-related nuclear receptor alpha120012
estrogen nuclear receptor alpha140014
peroxisome proliferator activated receptor gamma6006
aryl hydrocarbon receptor4004
thyroid hormone receptor beta isoform 28008
peripheral myelin protein 227007
cytochrome P450 3A4 isoform 15005
Gamma-aminobutyric acid receptor subunit pi5005
ATP-binding cassette sub-family C member 30808
Multidrug resistance-associated protein 40808
Solute carrier family 22 member 60303
Carbonic anhydrase 120101
UDP-glucuronosyltransferase 1A90001
Bile salt export pump0202
Voltage-dependent calcium channel gamma-2 subunit6006
Bile salt export pump0909
Cytochrome P450 2B10001
Cytochrome P450 1A10001
Carbonic anhydrase 10101
Carbonic anhydrase 20101
Myoglobin0101
Cytochrome P450 1A10012
Cytochrome P450 1A20102
Prostaglandin G/H synthase 10101
Carbonic anhydrase 30101
Cytochrome P450 3A40404
Cytochrome P450 2D60202
Cytochrome P450 2C9 0303
Polyunsaturated fatty acid lipoxygenase ALOX150101
Gamma-aminobutyric acid receptor subunit beta-15005
Sulfotransferase 1A1 0001
Gamma-aminobutyric acid receptor subunit delta5005
Gamma-aminobutyric acid receptor subunit gamma-25005
UDP-glucuronosyltransferase 1-60001
Glutamate receptor 26006
Gamma-aminobutyric acid receptor subunit alpha-55005
Gamma-aminobutyric acid receptor subunit alpha-35005
Arachidonate 5-lipoxygenase-activating protein0101
UDP-glucuronosyltransferase 1A1 0001
Carbonic anhydrase 40101
Prostaglandin G/H synthase 10101
Carbonic anhydrase 60101
Gamma-aminobutyric acid receptor subunit gamma-15005
Gamma-aminobutyric acid receptor subunit alpha-25005
Gamma-aminobutyric acid receptor subunit alpha-45005
Gamma-aminobutyric acid receptor subunit gamma-35005
Gamma-aminobutyric acid receptor subunit alpha-65005
Carbonic anhydrase 5A, mitochondrial0101
Prostaglandin G/H synthase 20102
Carbonic anhydrase 70101
Nuclear receptor ROR-gamma3003
Cytochrome P450 2J20303
Gamma-aminobutyric acid receptor subunit alpha-15005
Gamma-aminobutyric acid receptor subunit beta-35005
Gamma-aminobutyric acid receptor subunit beta-25005
Carbonic anhydrase 90101
GABA theta subunit5005
Canalicular multispecific organic anion transporter 10808
Carbonic anhydrase 150101
Carbonic anhydrase 130101
Gamma-aminobutyric acid receptor subunit epsilon5005
Carbonic anhydrase 140101
Carbonic anhydrase 5B, mitochondrial0101
toxin B0001
interleukin 84004
TDP1 protein7007
AR protein120012
estrogen receptor 2 (ER beta)6006
glucocorticoid receptor [Homo sapiens]9009
euchromatic histone-lysine N-methyltransferase 29009
Bloom syndrome protein isoform 13003
transcriptional regulator ERG isoform 31001
ras-related protein Rab-9A2002
nuclear factor erythroid 2-related factor 2 isoform 1100010
survival motor neuron protein isoform d4004
lamin isoform A-delta107007
Polyphenol oxidase 20101
Hypoxanthine-guanine phosphoribosyltransferase0001
Cellular tumor antigen p53100010
Xanthine dehydrogenase/oxidase [Includes: Xanthine dehydrogenase 0101
Adenosine receptor A2a0011
Xanthine dehydrogenase/oxidase0202
Nuclear receptor ROR-gamma0101
Xanthine dehydrogenase/oxidase0214
Purine nucleoside phosphorylase0011
TAR DNA-binding protein 431001
Shiga toxin subunit A0101
Histamine H3 receptor0101
Chain A, TYROSYL-DNA PHOSPHODIESTERASE5005
acetylcholinesterase2002
phosphopantetheinyl transferase3003
hypoxia-inducible factor 1 alpha subunit6006
SMAD family member 23003
Fumarate hydratase2002
USP1 protein, partial4004
NFKB1 protein, partial2002
PPM1D protein3003
SMAD family member 33003
Thrombopoietin3003
caspase 7, apoptosis-related cysteine protease2002
hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)4004
farnesoid X nuclear receptor4004
pregnane X nuclear receptor8008
G4004
cytochrome P450 2D63003
polyprotein2002
peroxisome proliferator-activated receptor delta6006
caspase-32002
thyroid stimulating hormone receptor2002
v-jun sarcoma virus 17 oncogene homolog (avian)8008
Histone H2A.x3003
cytochrome P450 2D6 isoform 12002
cellular tumor antigen p53 isoform a2002
cytochrome P450 2C9 precursor2002
D(1A) dopamine receptor2002
thyroid hormone receptor beta isoform a4004
potassium voltage-gated channel subfamily H member 2 isoform d2002
heat shock protein beta-11001
huntingtin isoform 21001
mitogen-activated protein kinase 12002
flap endonuclease 14004
serine/threonine-protein kinase mTOR isoform 11001
peptidyl-prolyl cis-trans isomerase NIMA-interacting 11001
urokinase-type plasminogen activator precursor1001
plasminogen precursor1001
urokinase plasminogen activator surface receptor precursor1001
nuclear receptor ROR-gamma isoform 13003
muscarinic acetylcholine receptor M13003
lethal factor (plasmid)4004
Polyunsaturated fatty acid lipoxygenase ALOX15B3003
Voltage-dependent L-type calcium channel subunit alpha-1C0101
Solute carrier organic anion transporter family member 1A40101
Voltage-dependent L-type calcium channel subunit alpha-1F0101
5-hydroxytryptamine receptor 40202
Lysine-specific demethylase PHF20101
Interferon beta6006
HLA class I histocompatibility antigen, B alpha chain 4004
Thyroid hormone receptor alpha0101
Receptor tyrosine-protein kinase erbB-20101
Integrin beta-31001
Tyrosine-protein kinase Fyn0101
ATP-dependent translocase ABCB10303
Aldo-keto reductase family 1 member B10202
Muscarinic acetylcholine receptor M20202
Muscarinic acetylcholine receptor M40202
ATP-dependent translocase ABCB10416
Integrin alpha-IIb1001
Beta-1 adrenergic receptor0202
Muscarinic acetylcholine receptor M50202
Alpha-2A adrenergic receptor0202
Adenosine receptor A30202
Cytochrome P450 2C80101
Thyroid hormone receptor alpha0101
Thyroid hormone receptor beta0101
Muscarinic acetylcholine receptor M10202
Beta-3 adrenergic receptor0202
D(2) dopamine receptor0202
Androgen receptor0707
Alpha-1B adrenergic receptor0202
Lethal factor0101
Alpha-2B adrenergic receptor0202
Thyroid hormone receptor beta0101
Muscarinic acetylcholine receptor M30202
ATP-dependent translocase ABCB10303
Substance-K receptor0202
D(1A) dopamine receptor0202
D(4) dopamine receptor0202
Carnitine O-palmitoyltransferase 2, mitochondrial0101
Sodium-dependent noradrenaline transporter 0202
Histamine H2 receptor0404
Endothelin-1 receptor0202
5-hydroxytryptamine receptor 2A0202
5-hydroxytryptamine receptor 2C0202
Lysine-specific demethylase 5A0101
B2 bradykinin receptor0202
Sodium-dependent serotonin transporter0202
Melanocortin receptor 40202
C-8 sterol isomerase0101
Melanocortin receptor 50202
Mu-type opioid receptor0202
D(3) dopamine receptor0202
Sodium channel protein type 1 subunit alpha0101
Sodium channel protein type 4 subunit alpha0101
Squalene synthase0101
Delta-type opioid receptor0202
Kappa-type opioid receptor0202
5-hydroxytryptamine receptor 2B0202
C-C chemokine receptor type 20202
Melanocortin receptor 30202
Alpha-1A adrenergic receptor0202
Histamine H2 receptor4217
D(1A) dopamine receptor1001
5-hydroxytryptamine receptor 60202
Carnitine O-palmitoyltransferase 1, liver isoform0101
C-C chemokine receptor type 40202
Spike glycoprotein3003
Sodium channel protein type 7 subunit alpha0101
Voltage-dependent L-type calcium channel subunit alpha-1D 0101
Sodium-dependent dopamine transporter 0202
Potassium voltage-gated channel subfamily H member 20101
Voltage-dependent L-type calcium channel subunit alpha-1S0101
Voltage-dependent L-type calcium channel subunit alpha-1C0101
Sodium channel protein type 5 subunit alpha0101
Squalene monooxygenase0101
3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase0101
Sodium channel protein type 9 subunit alpha0101
Lysine-specific demethylase 7A0101
Carnitine O-palmitoyltransferase 1, muscle isoform0101
Inositol hexakisphosphate kinase 14004
Sodium channel protein type 2 subunit alpha0101
Ataxin-26006
Sigma non-opioid intracellular receptor 10303
NAD-dependent protein deacetylase sirtuin-3, mitochondrial0011
Sodium channel protein type 3 subunit alpha0101
Sodium channel protein type 11 subunit alpha0101
Histone lysine demethylase PHF80101
Sodium channel protein type 8 subunit alpha0101
Sodium channel protein type 10 subunit alpha0101
cytochrome P450 2C9, partial4004
ATP-dependent phosphofructokinase6006
Chain A, MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASE3003
vitamin D (1,25- dihydroxyvitamin D3) receptor6006
arylsulfatase A3003
alpha-galactosidase2002
cytochrome P450 2C19 precursor3003
DNA polymerase kappa isoform 11001
M-phase phosphoprotein 82002
Solute carrier family 22 member 10101
Solute carrier family 22 member 20203
Solute carrier family 22 member 1 0202
Solute carrier family 22 member 20101
cGMP-specific 3',5'-cyclic phosphodiesterase0101
Potassium-transporting ATPase alpha chain 10101
Histamine H1 receptor0022
Potassium-transporting ATPase subunit beta0101
Aldehyde oxidase0101
Solute carrier family 22 member 60101
Solute carrier family 22 member 10202
Multidrug and toxin extrusion protein 20101
Solute carrier family 22 member 80203
Multidrug and toxin extrusion protein 10101
Histamine H4 receptor0101
Solute carrier family 22 member 110101
Solute carrier family 22 member 20202
Solute carrier family 22 member 40101
Solute carrier family 22 member 80202
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, N5-carboxyaminoimidazole ribonucleotide mutase0011
Chain B, N5-carboxyaminoimidazole ribonucleotide mutase0011
Chain A, N5-carboxyaminoimidazole ribonucleotide mutase0011
Chain B, N5-carboxyaminoimidazole ribonucleotide mutase0011
Chain A, JmjC domain-containing histone demethylation protein 3A1001
GLI family zinc finger 39009
hepatocyte nuclear factor 4-alpha isoform 20101
perilipin-50101
perilipin-10101
1-acylglycerol-3-phosphate O-acyltransferase ABHD5 isoform a0101
Beta-lactamase0101
Proto-oncogene tyrosine-protein kinase Src0101
3-dehydroquinate dehydratase0011
ATP-citrate synthase 0001
Ribonuclease T0001
Cell death-related nuclease 40001
3-dehydroquinate dehydratase0011
Prolyl 4-hydroxylase0101
Alpha-ketoglutarate-dependent dioxygenase FTO0101
Chain A, Beta-lactamase2002
Chain A, Ferritin light chain1001
Luciferase2002
endonuclease IV3003
PAX80001
thioredoxin reductase1001
pregnane X receptor2002
cytochrome P450 family 3 subfamily A polypeptide 44004
67.9K protein1001
glucocerebrosidase2002
cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a6006
activating transcription factor 62002
nuclear receptor subfamily 1, group I, member 24004
nuclear receptor subfamily 0 group B member 10101
nuclear factor erythroid 2-related factor 2 isoform 24004
atrial natriuretic peptide receptor 2 precursor1001
steroidogenic factor 10101
muscleblind-like protein 1 isoform 12002
caspase-1 isoform alpha precursor1001
neuropeptide S receptor isoform A1001
Solute carrier family 22 member 30101
Tubulin alpha-1A chain0213
Tubulin beta chain0213
Plasma kallikrein0001
Tubulin beta-4A chain0225
Tubulin beta chain0225
Tubulin alpha-3C chain0225
Serine/threonine-protein kinase pim-10101
Tubulin alpha-1B chain0225
Tubulin alpha-4A chain0225
Tubulin beta-4B chain0225
Vesicular acetylcholine transporter0101
Tubulin beta-3 chain0225
Tubulin beta-2A chain0225
Tubulin polymerization-promoting protein0011
Tubulin beta-8 chain0225
Tubulin beta-2B chain0202
Tubulin alpha-3E chain0225
Tubulin alpha-1A chain0225
Similar to alpha-tubulin isoform 1 0101
Similar to alpha-tubulin isoform 1 0101
CREB-binding protein1001
ATPase family AAA domain-containing protein 55005
Tubulin alpha-1C chain0225
Tubulin beta-6 chain0225
Tubulin beta-2B chain0225
Tubulin beta-1 chain0225
GALC protein2002
regulator of G-protein signaling 41001
Neuronal acetylcholine receptor subunit alpha-40112
Cytochrome P450 2A60101
Neuronal acetylcholine receptor subunit beta-20112
Cytochrome P450 2A50101
Eyes absent homolog 20101
Amyloid-beta precursor protein0101
Angiotensin-converting enzyme 0101
Metallo-beta-lactamase VIM-130101
Beta-lactamase 0101
Beta-lactamase 0101
Beta-lactamase VIM-1 0101
Chain A, Putative fructose-1,6-bisphosphate aldolase3003
Chain A, HADH2 protein3003
Chain B, HADH2 protein3003
peripheral myelin protein 22 isoform 12002
Neutral amino acid transporter A0101
Asc-type amino acid transporter 10101
Neutral amino acid transporter B(0)0101
Proton-coupled amino acid transporter 10101
Amino acid transporter0101
nonstructural protein 12002
bromodomain adjacent to zinc finger domain 2B1001
Nuclear receptor subfamily 1 group I member 20011
Glucocorticoid receptor08316
Glycine receptor subunit alpha-10808
Glycine receptor subunit beta0808
Glycine receptor subunit alpha-20808
Glycine receptor subunit alpha-30808
Nuclear receptor subfamily 1 group I member 20011
vitamin D3 receptor isoform VDRA3003
Cystathionine gamma-lyase0101
Succinyl-diaminopimelate desuccinylase0101
Chain A, 2-oxoglutarate Oxygenase1001
15-lipoxygenase, partial1001
Chain A, Immunoglobulin0011
Chain B, Immunoglobulin0011
Glutamate receptor ionotropic, NMDA 2D0101
Glutamate receptor ionotropic, NMDA 3B0101
Muscarinic acetylcholine receptor M10011
Muscarinic acetylcholine receptor M30011
Muscarinic acetylcholine receptor M40011
Muscarinic acetylcholine receptor M50011
Muscarinic acetylcholine receptor M20011
Muscarinic acetylcholine receptor M10012
Cytochrome P450 2B60101
Sodium-dependent serotonin transporter0202
Muscarinic acetylcholine receptor M40012
Delta-type opioid receptor0001
Kappa-type opioid receptor0001
Glutamate receptor ionotropic, NMDA 1 0202
Lysosomal Pro-X carboxypeptidase0101
Mu-type opioid receptor0001
Glutamate receptor ionotropic, NMDA 2A 0202
Glutamate receptor ionotropic, NMDA 2B0202
Glutamate receptor ionotropic, NMDA 2C0203
Cholinesterase0101
Glutamate receptor ionotropic, NMDA 10202
Glutamate receptor ionotropic, NMDA 2A0202
Glutamate receptor ionotropic, NMDA 2B0202
Glutamate receptor ionotropic, NMDA 2C0101
Glutamate receptor ionotropic, NMDA 2D0202
Glutamate receptor ionotropic, NMDA 3A0101
Glutamate receptor ionotropic, NMDA 3B0202
Muscarinic acetylcholine receptor M50012
Muscarinic acetylcholine receptor M30012
Muscarinic acetylcholine receptor M20012
Sigma non-opioid intracellular receptor 10202
Glutamate receptor ionotropic, NMDA 3A0202
luciferase0001
Fatty acid-binding protein, liver0101
Estrogen receptor0303
Progesterone receptor0304
Glucocorticoid receptor0213
Glucocorticoid receptor0011
Corticosteroid-binding globulin0101
Mineralocorticoid receptor 0325
Androgen receptor0202
Glutamine synthetase0011
Nociceptin receptor0011
Estrogen receptor beta0303
thioredoxin glutathione reductase1001
glp-1 receptor, partial1001
nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105), isoform CRA_a2002
Interleukin-50101
Interleukin-50101
Matrix metalloproteinase-90101
Interleukin-5 receptor subunit alpha0101
Chain A, ATP-DEPENDENT DNA HELICASE Q11001
Chain A, Cruzipain1001
15-hydroxyprostaglandin dehydrogenase [NAD(+)] isoform 11001
histone acetyltransferase KAT2A isoform 11001
Bifunctional epoxide hydrolase 20101
Peroxisome proliferator-activated receptor alpha1001
DNA polymerase iota isoform a (long)1001
Rap guanine nucleotide exchange factor 31001
Urease subunit alpha0101
Urease subunit beta0101
Olfactory receptor 51E20011
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]