Autosomal Dominant Hereditary Spastic Paraplegia

Synonym
Hereditary Motor-Sensory Neuropathy with Pyramidal Signs
Peroneal Muscular Atrophy with Pyramidal Features, Autosomal Dominant
Hereditary Spastic Paraplegia
Hereditary Spastic Paraplegia, Autosomal Recessive
Hereditary X-Linked Recessive Spastic Paraplegia
Hereditary, Spastic Paraplegia, Autosomal Dominant
Hereditary, Spastic Paraplegia, X-Linked Recessive
HMSN 5
HMSN Type V
HMSN V
HMSN V (Hereditary Motor and Sensory Neuropathy Type V)
Charcot-Marie-Tooth Disease with Pyramidal Features, Autosomal Dominant
CMT with Pyramidal Features
Autosomal Dominant Hereditary Spastic Paraplegia
Autosomal Dominant Spastic Paraplegia Hereditary
Autosomal Recessive Hereditary Spastic Paraplegia
Autosomal Recessive Spastic Paraplegia, Hereditary
Paraplegia, Spastic, Hereditary
Type V Hereditary Motor and Sensory Neuropathy
Spastic Paraplegia, Autosomal Dominant, Hereditary
Spastic Paraplegia, X-Linked Recessive, Hereditary
Spastic Paraplegia, Hereditary, X-Linked Recessive
Spastic Paraplegia, Hereditary, Autosomal Recessive
Spastic Paraplegia, Hereditary, Autosomal Dominant
Spastic Paraplegia, Autosomal Recessive, Hereditary
Spastic Paraplegia-Hypertrophic Motor-Sensory Neuropathy
Spastic Paraplegia Type 2
Spastic Paraplegia 2
X Linked Recessive Hereditary Spastic Paraplegia
X-linked Recessive Hereditary Spastic Paraplegia
Hypertrophic Motor-Sensory Neuropathy-Spastic Paraplegia
X-Linked, Spastic Paraplegia, Hereditary
Hereditary Autosomal Dominant Spastic Paraplegia
Hereditary Autosomal Recessive Spastic Paraplegia
Hereditary Motor and Sensory Neuropathy 5
Hereditary Motor And Sensory Neuropathy V

Excerpt	Reference
"Hereditary spastic paraplegia is a group of clinically and genetically heterogeneous disorders consisting of pure and complicated forms."	( Auer-Grumbach, M; Fazekas, F; Hartung, HP; Irmler, A; Radner, H; Strasser-Fuchs, S, 1999)
"The hereditary spastic paraplegias are a clinically variable and genetically heterogeneous group of disorders characterized by progressive and lower limb spasticity and weakness."	( Allen, I; Crosby, AH; Hart, PE; Jeffery, S; Patel, H; Patton, MA; Phillimore, HE; Silver, JR; Warner, T; Wood, NW, 2001)
"Hereditary spastic paraplegia is a highly heterogeneous group of neurogenetic disorders with pure and complicated clinical phenotypes."	( Abramsky, O; Gal, A; Heyman, SN; Karp, N; Kohn, Y; Korman, SH; Leclerc, D; Lossos, A; Meiner, V; Milman, T; Newman, JP; Rosenblatt, DS; Rozen, R; Schwahn, BC; Shaag, A; Steiner-Birmanns, B; Teltsh, O; Watkins, D, 2014)
"Hereditary spastic paraplegia is characterized by progressive spasticity and relatively mild muscle weakness of the lower limbs."	( de Bot, ST; de Niet, M; Geurts, AC; van de Warrenburg, BP; Weerdesteyn, V, 2015)
"Hereditary spastic paraplegias are heterogeneous neurological disorders characterized by a pyramidal syndrome with symptoms predominantly affecting the lower limbs."	( Alonso, I; Brice, A; Calvas, P; Charles, P; Coutelier, M; Coutinho, P; Darios, F; Depienne, C; Dionne-Laporte, A; Durand, CM; Durr, A; Gaussen, M; Goizet, C; Habarou, F; Jacoupy, M; Janin, M; Kennerson, M; Konop, J; Loureiro, JL; Mairey, M; Matusiak, R; Mochel, F; Morais, S; Morice-Picard, F; Nicholson, G; Ottolenghi, C; Rouleau, G; Saudubray, JM; Schule, R; Stevanin, G; Stoll, M; Tallaksen, C; Tao, F; Zuchner, S, 2015)
"Hereditary spastic paraplegias are heterogeneous neurodegenerative disorders characterized by progressive spasticity of the lower limbs due to degeneration of the corticospinal motor neurons."	( Andreeva, A; Asselbergh, B; Chamova, T; Chang, DI; De Rycke, R; Estrada-Cuzcano, A; Holemans, T; Jordanova, A; Klein, C; Martin, S; Mollerup Sørensen, D; Pöppel, T; Reichbauer, J; Samuel, J; Schöls, L; Schüle, R; Synofzik, M; Timmann, D; Tournev, I; van Veen, S; Vangheluwe, P; Zuchner, S, 2017)
"The hereditary spastic paraplegias are an expanding and heterogeneous group of disorders characterized by spasticity in the lower limbs."	( Babin, PJ; Banneau, G; Benyounes, I; Castelnovo, G; Coupry, I; Debs, R; Durr, A; Ewenczyk, C; Goizet, C; Guissart, C; Hajage, D; Humbert, L; Labauge, P; Lafourcade, A; Lamari, F; Lavie, J; Lesca, G; Marelli, C; Mochel, F; Monin, ML; Odent, S; Ollagnon, E; Petit, E; Pilliod, J; Rainteau, D; Stevanin, G; Thauvin-Robinet, C; Ullmann, U; Wolf, C, 2018)
"Hereditary spastic paraplegias are characterized by lower limb spasticity resulting from degeneration of long corticospinal axons."	( Blackstone, C; Chai, E; Chen, Z; Li, XJ; Mou, Y; Roda, RH, 2022)
"For example, hereditary spastic paraplegia is associated with >80 genes, with frequently only few affected individuals described for each gene."	( Abbaszadegan, MR; Al-Sannaa, NA; Alavi, S; Bahreini, A; Bakhtiari, S; Barakat, TS; Bauer, P; Bouman, A; Boycott, KM; Calame, DG; Coban-Akdemir, Z; Donis, KC; Du, H; Ebrahimzadeh-Vesal, R; Elsea, SH; Emrick, LT; Fatih, JM; Fellig, Y; Gibbs, RA; Gijavanekar, C; Grochowski, CM; Herman, I; Hosseini, S; Houlden, H; Hunter, JV; Ito, YA; Jaddoa, AG; Jamshidi, Y; Jhangiani, SN; Jin, SC; Kalish, Y; Karimiani, EG; Kernohan, KD; Kruer, MC; Lossos, A; Lupski, JR; Marafi, D; Maroofian, R; Marshall, AE; Meiner, V; Mitani, T; Morales Saute, JA; Muirhead, K; Murphy, D; Nicita, F; Osmond, M; Pehlivan, D; Posey, JE; Prus, E; Robson, SC; Rocca, C; Ruivenkamp, C; Saadi, NW; Salehi, MM; Silva, TO; Skidmore, DL; Sousa, SB; Suerink, M; Sutton, VR; Tajsharghi, H; Travaglini, L; Vanderver, A; Zaki, MS; Zarean, E; Zifarelli, G, 2022)
"Hereditary spastic paraplegia is a neurological condition characterized by predominant axonal degeneration in long spinal tracts, leading to weakness and spasticity in the lower limbs."	( Barth, E; Evangelista, G; Langer, T; Molinié, T; Montoro-Gámez, C; Nolte, H; Popovic, M; Rugarli, EI; Trifunovic, A; Tröder, SE; Zevnik, B, 2023)

Excerpt	Reference
"Patients with hereditary spastic paraplegia (HSP) are often treated with antispastic drugs to relieve symptoms but documentation is lacking."	( Fenger, K; Jennum, P; Nielsen, JE; Rogvi-Hansen, Bá; Scheuer, KH; Svenstrup, K; Werdelin, L, 2007)
"We describe one Italian autosomal recessive hereditary spastic paraplegia with thin corpus callosum patient who unusually presented at onset, 16 years, with parkinsonism-like features, responsive to dopaminergic therapy."	( Bentivoglio, AR; Guidubaldi, A; Petracca, M; Piano, C; Santorelli, FM; Silvestri, G; Tessa, A, 2011)

Timeframe	Studies, This Condition (%)	All Conditions %
pre-1990	5 (2.51)	23.3326
1990's	19 (9.55)	12.5806
2000's	44 (22.11)	18.1394
2010's	87 (43.72)	28.8240
2020's	44 (22.11)	9.53

Drug	Relationship Strength	Studies	Trials
gamma-aminobutyric acid	medium	1	1
acetic acid	low	1	0
adenine	low	1	0
betaine	low	1	0
carnitine	low	1	0
choline	low	2	0
creatine	low	3	0
cytosine	low	1	0
glycerol	low	1	0
inositol	low	2	0
nitrous oxide	low	2	0
thymine	low	1	0
urea	low	1	0
1-anilino-8-naphthalenesulfonate	low	1	0
beta-resorcylic acid	low	1	0
meglutol	low	1	0
4-aminopyridine	medium	2	1
baclofen	medium	15	5
chlorpyrifos	low	1	0
conduritol epoxide	low	1	0
fentanyl	low	1	0
flumazenil	low	1	0
gabapentin	medium	1	1
haloperidol	low	1	0
iofetamine	low	1	0
nocodazole	low	2	0
methylphenidate	low	1	0
papaverine	low	1	0
phenazine	low	1	0
sevoflurane	low	2	0
trimebutine	low	1	0
isoflurophate	low	1	0
alanine	low	1	0
serine	low	3	0
aspartic acid	low	2	0
glutamine	low	2	0
lysine	low	1	0
tetrabenazine	low	1	0
phenylephrine	low	1	0
levodopa	low	10	0
tyrosine	low	3	0
leucine	low	3	0
cytidine diphosphate	low	1	0
ornithine	low	5	0
asparagine	low	1	0
valine	low	1	0
threonine	medium	3	1
isoleucine	low	1	0
arginine	low	4	0
mipafox	low	1	0
chenodeoxycholic acid	low	2	0
eosine yellowish-(ys)	low	1	0
3-methylglutaric acid	low	1	0
d-alpha tocopherol	low	1	0
o,o-diethyl o-3,5,6-trichloro-2-pyridyl phosphate	low	1	0
manganese	low	1	0
trolamine salicylate	low	2	0
selegiline	low	1	0
1-deoxynojirimycin	low	1	0
phenyl valerate	low	1	0
iodine	low	1	0
glutamic acid	low	5	0
s-adenosylmethionine	low	1	0
paclitaxel	low	2	0
fomesafen	low	1	0
simvastatin	low	3	0
fura-2	low	1	0
atorvastatin	medium	2	2
duloxetine hydrochloride	low	1	0
3-iodobenzylguanidine	low	1	0
n-acetylaspartic acid	low	2	0
25-hydroxycholesterol	medium	3	2
fluorodeoxyglucose f18	low	2	0
tebuconazole	low	1	0
homocysteine	low	1	0
acetoacetyl coa	low	1	0
carbidopa, levodopa drug combination	low	1	0
valerates	low	1	0
dihydrotetrabenazine	low	1	0
27-hydroxycholesterol	medium	7	2
proline	low	3	0
ezetimibe	low	2	0
ropivacaine	low	1	0
migalastat	low	1	0
cholic acid	low	1	0
deoxycholic acid	medium	1	1
leupeptins	low	1	0
inositol 1,4,5-trisphosphate	low	1	0
rocuronium	low	2	0
acetyl coenzyme a	low	1	0
resveratrol	medium	1	1
oleic acid	low	1	0
gw 3965	low	1	0
epothilone a	low	1	0
benzyloxycarbonylleucyl-leucyl-leucine aldehyde	low	1	0
crotamiton	low	1	0
benztropine	low	1	0
3-methylglutaconic acid	low	4	0
thiopental	low	1	0
3-(2,4-dichloro-5-methoxyphenyl)-2-sulfanyl-4(3h)-quinazolinone	low	1	0
myelin basic protein	low	1	0
phenylephrine hydrochloride	low	1	0
sirolimus	low	1	0
ubiquinone 7	low	2	0
casein kinase ii	low	1	0
aluminum	low	1	0
cysteine	low	4	0
staurosporine	low	1	0
arachidonoylserotonin	low	1	0
2-carbomethoxy-8-(3-fluoropropyl)-3-(4-iodophenyl)tropane	low	1	0
alpha-synuclein	low	1	0
delta-1-pyrroline-5-carboxylate	low	1	0
24-hydroxycholesterol	low	1	0
nad	low	2	0
angiotensinogen	low	1	0
oligonucleotides	low	1	0
ubiquinone	low	1	0
calpain	low	13	0
glycolipids	low	1	0
ascorbic acid	low	1	0
epidermal growth factor	low	1	0
transforming growth factor beta	low	1	0
apyrase	low	1	0
guanosine triphosphate	low	1	0
guanine	low	2	0
folic acid	low	1	0
eye	low	2	0
carbidopa	low	1	0

Protein Targets (1,403)

Protein	Potency Measurements	Inhibition Measurements	Activation Measurements	Drugs
Chain B, pheromone binding protein	0	0	1	1
Chain A, pheromone binding protein	0	0	1	1
Chain A, JmjC domain-containing histone demethylation protein 3A	7	0	0	7
Chain A, RNA-directed RNA polymerase NS5	0	1	0	1
acid sphingomyelinase	2	0	0	2
thioredoxin reductase	18	0	0	18
USP1 protein, partial	11	0	0	11
TDP1 protein	25	0	0	25
vitamin D3 receptor isoform VDRA	8	0	0	8
importin subunit beta-1 isoform 1	6	0	0	6
flap endonuclease 1	7	0	0	7
serine/threonine-protein kinase PLK1	4	0	0	4
snurportin-1	6	0	0	6
peptidyl-prolyl cis-trans isomerase NIMA-interacting 1	5	0	0	5
GTP-binding nuclear protein Ran isoform 1	4	0	0	4
DNA polymerase eta isoform 1	3	0	0	3
DNA polymerase iota isoform a (long)	9	0	0	9
urokinase-type plasminogen activator precursor	4	0	0	4
plasminogen precursor	4	0	0	4
urokinase plasminogen activator surface receptor precursor	4	0	0	4
geminin	30	0	0	30
DNA polymerase kappa isoform 1	9	0	0	9
fibroblast growth factor 22 isoform 1 precursor	0	0	0	1
Mitogen-activated protein kinase 13	0	1	0	1
Beta-lactamase	0	1	0	1
Transthyretin	0	0	2	2
Fatty acid-binding protein, intestinal	0	1	1	2
Fatty acid-binding protein, adipocyte	0	3	1	4
Cyclin-A2	0	2	0	2
Cannabinoid receptor 1	0	0	1	1
Cyclin-dependent kinase 2	0	2	2	4
Choline O-acetyltransferase	0	1	0	1
Mitogen-activated protein kinase 12	0	1	0	1
Guanine nucleotide-binding protein G	2	0	0	2
Fatty acid-binding protein 5	0	1	1	2
Fatty acid-binding protein 5	0	0	1	1
Mitogen-activated protein kinase 11	0	1	1	2
Mitogen-activated protein kinase 14	0	1	1	2
Chain A, MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASE	17	0	0	17
glucocerebrosidase	5	0	0	5
Alpha-mannosidase	0	1	0	1
alpha-galactosidase	4	0	0	4
Trehalase	0	1	0	1
lysosomal alpha-glucosidase preproprotein	7	0	0	7
Trehalase	0	1	0	1
Maltase-glucoamylase, intestinal	0	2	0	2
Trehalase	0	1	0	1
Lysosomal acid glucosylceramidase	0	2	0	2
Alpha-galactosidase A	0	2	0	2
Alpha-glucosidase MAL62	0	1	0	1
Lactase-phlorizin hydrolase	0	2	0	2
Lysosomal alpha-glucosidase	0	3	0	3
Beta-glucosidase A	0	2	0	2
Sucrase-isomaltase, intestinal	0	2	0	2
Alpha-1B adrenergic receptor	0	6	0	6
Sucrase-isomaltase, intestinal	0	2	0	2
Alpha-1D adrenergic receptor	0	6	0	6
Beta-glucosidase	0	1	0	1
Protein-lysine 6-oxidase	0	2	0	2
Alpha-mannosidase 2	0	1	0	1
Glycogen debranching enzyme	0	2	0	2
Glycogen debranching enzyme	0	1	0	1
Alpha-glucosidase MAL32	0	2	0	2
Alpha-1A adrenergic receptor	0	6	0	6
Oligo-1,6-glucosidase IMA1	0	1	0	1
Alpha-glucosidase MAL12	0	3	0	3
Oxysterols receptor LXR-beta	0	3	1	4
Spike glycoprotein	13	0	1	14
Alpha-amylase	0	1	0	1
Trehalose synthase/amylase TreS	0	1	0	1
Lactase-phlorizin hydrolase	0	2	0	2
Oxysterols receptor LXR-alpha	0	2	4	6
Neutral alpha-glucosidase AB	0	2	0	2
Ceramide glucosyltransferase	0	2	0	2
Lysosomal acid glucosylceramidase	0	1	0	1
Probable maltase-glucoamylase 2	0	1	0	1
Beta-glucosidase	0	1	0	1
Lysosomal alpha-glucosidase	0	2	0	2
Cytosolic beta-glucosidase	0	1	0	1
Non-lysosomal glucosylceramidase	0	2	0	2
Putative alpha-glucosidase	0	1	0	1
Sodium-dependent dopamine transporter	0	7	0	7
cytochrome P450 family 3 subfamily A polypeptide 4	15	0	0	15
estrogen nuclear receptor alpha	32	0	0	32
peripheral myelin protein 22	13	0	0	13
Alpha-crystallin B chain	0	0	1	1
3-hydroxy-3-methylglutaryl-coenzyme A reductase	0	7	1	8
Cellular tumor antigen p53	20	0	0	20
Integrin beta-3	1	1	2	4
Integrin alpha-V	0	1	1	2
Nuclear receptor ROR-gamma	4	0	1	5
Glutamate receptor ionotropic, NMDA 1	0	1	1	2
Sterol regulatory element-binding protein 2	0	1	0	1
Glutamate receptor ionotropic, NMDA 2A	0	1	1	2
Glutamate receptor ionotropic, NMDA 2B	0	1	1	2
Oxysterol-binding protein 2	0	0	1	1
NPC1-like intracellular cholesterol transporter 1	0	1	1	2
Chain A, Ferritin light chain	9	0	0	9
glp-1 receptor, partial	11	0	0	11
Smad3	5	0	0	5
nonstructural protein 1	3	0	0	3
67.9K protein	10	0	0	10
IDH1	12	0	0	12
euchromatic histone-lysine N-methyltransferase 2	25	0	0	25
polyunsaturated fatty acid lipoxygenase ALOX12	3	0	0	3
15-hydroxyprostaglandin dehydrogenase [NAD(+)] isoform 1	3	0	0	3
chromobox protein homolog 1	15	0	0	15
nuclear receptor ROR-gamma isoform 1	11	0	0	11
neuropeptide S receptor isoform A	5	0	0	5
TAR DNA-binding protein 43	10	0	0	10
dopamine D1 receptor	4	0	0	4
GLS protein	10	0	0	10
Thrombopoietin	5	0	0	5
hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)	8	0	0	8
cytochrome P450 2D6 isoform 1	5	0	0	5
cytochrome P450 2C19 precursor	5	0	0	5
ras-related protein Rab-9A	5	0	0	5
histone acetyltransferase KAT2A isoform 1	8	0	0	8
lethal factor (plasmid)	11	0	0	11
POU domain, class 2, transcription factor 1	0	0	0	2
ATP-dependent phosphofructokinase	13	0	0	13
Chain A, Cruzipain	3	0	0	3
RAR-related orphan receptor gamma	21	0	0	21
Microtubule-associated protein tau	9	0	0	9
aldehyde dehydrogenase 1 family, member A1	15	0	0	15
thyroid stimulating hormone receptor	12	0	0	12
estrogen receptor 2 (ER beta)	11	0	0	11
glucocorticoid receptor [Homo sapiens]	19	0	0	19
cytochrome P450 2D6	7	0	0	7
nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105), isoform CRA_a	7	0	0	7
transcriptional regulator ERG isoform 3	4	0	0	4
thyroid hormone receptor beta isoform 2	17	0	0	17
mitogen-activated protein kinase 1	6	0	0	6
survival motor neuron protein isoform d	6	0	0	6
lamin isoform A-delta10	21	0	0	21
Potassium channel subfamily K member 2	0	1	1	2
Rap guanine nucleotide exchange factor 3	5	0	0	5
Potassium voltage-gated channel subfamily A member 3	0	0	1	1
Acetylcholinesterase	0	1	0	1
Pteridine reductase 1	0	1	0	1
Potassium voltage-gated channel subfamily A member 1	0	1	0	1
Potassium voltage-gated channel subfamily H member 2	0	9	0	9
Free fatty acid receptor 3	0	0	1	1
Free fatty acid receptor 2	0	1	1	2
Tyrosine-protein kinase Lck	0	2	2	4
Tyrosine-protein kinase Fyn	0	2	2	4
Fibrinogen C domain-containing protein 1	0	1	0	1
Chain A, 2-ENOYL-COA HYDRATASE	0	1	0	1
Chain B, 2-ENOYL-COA HYDRATASE	0	1	0	1
N-alpha-acetyltransferase 50	0	0	1	1
Chain A, MTA/SAH nucleosidase	0	1	0	1
Chain A, Ribosome-inactivating protein alpha-trichosanthin	0	0	1	1
Chain A, Ricin A chain	0	0	1	1
Chain A, Ribosome-inactivating protein 3	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
AR protein	27	0	0	27
nuclear receptor subfamily 1, group I, member 3	15	0	0	15
estrogen-related nuclear receptor alpha	22	0	0	22
pregnane X nuclear receptor	18	0	0	18
cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a	10	0	0	10
nuclear factor erythroid 2-related factor 2 isoform 2	11	0	0	11
heat shock protein beta-1	8	0	0	8
tumor susceptibility gene 101 protein	1	0	0	1
Voltage-dependent calcium channel gamma-2 subunit	9	0	0	9
Bile salt export pump	0	24	0	24
Cyclin-dependent kinase 1	0	1	1	2
Heat shock protein HSP 90-beta	0	1	0	1
Glutamate receptor 2	9	2	1	12
Xanthine dehydrogenase/oxidase	0	1	0	1
Protein mono-ADP-ribosyltransferase PARP15	0	1	0	1
Leucine-rich repeat serine/threonine-protein kinase 2	0	2	0	2
ATPase family AAA domain-containing protein 5	7	0	0	7
Ataxin-2	8	0	0	8
Chain A, TYROSYL-DNA PHOSPHODIESTERASE	7	0	0	7
Carbonic anhydrase 1	0	6	0	14
Carbonic anhydrase 2	0	6	1	15
Alanine racemase, biosynthetic	0	0	0	1
5-hydroxytryptamine receptor 1D	0	0	0	2
Glutamate receptor ionotropic, NMDA 1	0	6	2	10
Proton-coupled amino acid transporter 1	0	8	0	9
Adenosine deaminase	0	0	0	1
Carbonic anhydrase 4	0	2	0	4
Fatty-acid amide hydrolase 1	0	2	0	2
Transient receptor potential cation channel subfamily A member 1	0	1	2	3
Prostaglandin G/H synthase 2	0	4	0	4
Fatty-acid amide hydrolase 1	0	3	0	3
Transient receptor potential cation channel subfamily V member 1	0	1	0	1
Chain E, LYSINE, ARGININE, ORNITHINE-BINDING PROTEIN	0	0	2	2
Chain E, LYSINE, ARGININE, ORNITHINE-BINDING PROTEIN	0	0	2	2
Chain E, LYSINE, ARGININE, ORNITHINE-BINDING PROTEIN	0	0	2	2
phosphopantetheinyl transferase	13	0	0	13
NFKB1 protein, partial	7	0	0	7
muscarinic acetylcholine receptor M1	8	0	0	8
Cytochrome P450 3A4	0	8	0	10
Nitric oxide synthase, endothelial	0	0	0	2
Nitric oxide synthase, brain	0	0	0	1
Nitric oxide synthase, brain	0	0	0	1
Nitric oxide synthase, inducible	0	1	0	2
Nitric oxide synthase, inducible	0	0	1	3
Cationic amino acid transporter 3	0	2	0	2
5-hydroxytryptamine receptor 3E	0	2	0	2
acetylcholinesterase	7	0	0	7
hypoxia-inducible factor 1 alpha subunit	7	0	0	7
SMAD family member 2	6	0	0	6
Fumarate hydratase	6	0	0	6
PPM1D protein	5	0	0	5
SMAD family member 3	6	0	0	6
GLI family zinc finger 3	22	0	0	22
progesterone receptor	12	0	0	12
EWS/FLI fusion protein	11	0	0	11
retinoic acid nuclear receptor alpha variant 1	18	0	0	18
retinoid X nuclear receptor alpha	17	0	0	17
farnesoid X nuclear receptor	9	0	0	9
G	7	0	0	7
polyprotein	6	0	0	6
peroxisome proliferator-activated receptor delta	16	0	0	16
peroxisome proliferator activated receptor gamma	15	0	0	15
vitamin D (1,25- dihydroxyvitamin D3) receptor	16	0	0	16
heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)	2	0	0	2
thyroid stimulating hormone receptor	8	0	0	8
v-jun sarcoma virus 17 oncogene homolog (avian)	11	0	0	11
mu-type opioid receptor isoform MOR-1	0	0	2	2
potassium voltage-gated channel subfamily H member 2 isoform d	9	0	0	9
nuclear factor erythroid 2-related factor 2 isoform 1	18	0	0	18
5-hydroxytryptamine receptor 2A	0	0	2	2
Solute carrier family 22 member 2	0	1	0	2
ATP-binding cassette sub-family C member 3	0	13	0	13
Multidrug resistance-associated protein 4	0	13	0	14
5-hydroxytryptamine receptor 3A	0	1	0	1
5-hydroxytryptamine receptor 3B	0	2	0	2
Interferon beta	10	0	0	10
HLA class I histocompatibility antigen, B alpha chain	7	0	0	7
ATP-dependent translocase ABCB1	0	9	0	14
5-hydroxytryptamine receptor 1A	0	4	2	6
5-hydroxytryptamine receptor 2C	0	5	0	5
Neuronal acetylcholine receptor subunit alpha-4	2	3	0	5
Neuronal acetylcholine receptor subunit beta-2	2	3	0	5
D(2) dopamine receptor	0	7	2	11
5-hydroxytryptamine receptor 2A	0	5	0	5
Alpha-2C adrenergic receptor	0	8	3	11
D	0	4	0	4
5-hydroxytryptamine receptor 1A	0	5	0	6
Muscarinic acetylcholine receptor M3	0	6	0	6
D(1A) dopamine receptor	0	5	0	6
D(4) dopamine receptor	0	6	1	9
D(1B) dopamine receptor	0	3	0	4
Alpha-1D adrenergic receptor	0	7	0	7
5-hydroxytryptamine receptor 2A	0	9	0	9
5-hydroxytryptamine receptor 2C	0	8	0	8
D(4) dopamine receptor	0	4	0	4
Histamine H1 receptor	0	2	0	2
Sodium-dependent serotonin transporter	0	8	0	8
5-hydroxytryptamine receptor 7	0	2	0	2
5-hydroxytryptamine receptor 7	0	3	0	3
Alpha-1A adrenergic receptor	0	5	1	6
Histamine H1 receptor	0	9	1	10
Alpha-1B adrenergic receptor	0	4	1	5
D(3) dopamine receptor	0	8	2	12
5-hydroxytryptamine receptor 2B	0	9	0	9
5-hydroxytryptamine receptor 3A	0	2	0	2
5-hydroxytryptamine receptor 6	0	6	0	6
3-hydroxy-3-methylglutaryl-coenzyme A reductase	0	4	0	4
D(2) dopamine receptor	0	6	0	6
Inositol monophosphatase 1	5	0	0	5
5-hydroxytryptamine receptor 3D	0	2	0	2
Multidrug and toxin extrusion protein 2	0	1	0	1
5-hydroxytryptamine receptor 3C	0	2	0	2
Inositol hexakisphosphate kinase 1	7	0	0	7
Canalicular multispecific organic anion transporter 1	0	13	0	13
Multidrug and toxin extrusion protein 1	0	1	0	1
Histamine H3 receptor	0	1	0	1
cytochrome P450 2C9, partial	7	0	0	7
Chain A, Hyaluronidase, phage associated	0	1	0	1
thioredoxin glutathione reductase	2	0	0	2
lethal(3)malignant brain tumor-like protein 1 isoform I	2	0	0	2
Polyphenol oxidase 2	0	2	0	4
Pancreatic alpha-amylase	0	2	0	2
Albumin	0	1	0	1
Urease	0	1	0	1
Prolyl 4-hydroxylase subunit alpha-1	0	0	0	1
Tyrosinase	0	3	0	3
Alpha-2B adrenergic receptor	0	9	3	12
Hyaluronate lyase	0	1	0	1
Prolyl hydroxylase EGLN2	0	0	0	1
Egl nine homolog 1	0	0	0	1
Prolyl hydroxylase EGLN3	0	0	0	1
Hypoxia-inducible factor 1-alpha inhibitor	0	0	0	1
Solute carrier family 23 member 1	0	1	0	1
Neutral amino acid transporter A	0	4	0	4
Neutral amino acid transporter B(0)	0	4	0	4
Carbonic anhydrase-like protein, putative	0	0	0	6
Amino acid transporter	0	4	0	4
arylsulfatase A	10	0	0	10
Bloom syndrome protein isoform 1	13	0	0	13
Metabotropic glutamate receptor 6	0	1	2	4
Excitatory amino acid transporter 4	0	2	0	2
Glutamate transporter homolog	0	0	1	1
N(4)-(beta-N-acetylglucosaminyl)-L-asparaginase	0	1	0	1
Excitatory amino acid transporter 1	0	3	0	4
Excitatory amino acid transporter 2	0	3	0	4
Excitatory amino acid transporter 3	0	3	0	4
Glutamate receptor ionotropic, NMDA 2A	0	4	2	8
Glutamate receptor ionotropic, NMDA 2B	0	5	2	9
Glutamate receptor ionotropic, NMDA 2C	0	4	2	8
Metabotropic glutamate receptor 1	0	1	2	4
Metabotropic glutamate receptor 2	0	1	2	4
Glutamate receptor ionotropic, NMDA 2D	0	4	2	8
Glutamate receptor ionotropic, NMDA 3B	0	4	2	8
Glutamate receptor ionotropic, NMDA 3A	0	4	2	8
caspase 7, apoptosis-related cysteine protease	7	0	0	7
caspase-3	7	0	0	7
Caspase-7	3	0	0	3
thyroid hormone receptor beta isoform a	6	0	0	6
caspase-3	3	0	0	3
Solute carrier organic anion transporter family member 2B1	0	0	0	1
Insulin receptor	0	2	0	2
Dipeptidyl peptidase 4	0	1	0	1
Histone deacetylase 1	0	2	0	2
Histone deacetylase 2	0	2	0	2
Solute carrier organic anion transporter family member 1B3	0	2	0	3
Histone deacetylase 6	0	2	0	2
Broad substrate specificity ATP-binding cassette transporter ABCG2	0	2	0	2
Solute carrier organic anion transporter family member 1B1	0	5	0	6
ATAD5 protein, partial	9	0	0	9
regulator of G-protein signaling 4	9	0	0	9
activating transcription factor 6	8	0	0	8
D(1A) dopamine receptor	4	0	0	4
cytochrome P450 3A4 isoform 1	8	0	0	8
Gamma-aminobutyric acid receptor subunit pi	8	5	0	13
Gamma-aminobutyric acid type B receptor subunit 2	0	2	2	4
Gamma-aminobutyric acid type B receptor subunit 2	0	3	0	3
Gamma-aminobutyric acid receptor subunit beta-1	8	5	0	13
Gamma-aminobutyric acid receptor subunit delta	8	5	0	13
Gamma-aminobutyric acid receptor subunit gamma-2	8	5	2	15
Gamma-aminobutyric acid receptor subunit alpha-5	8	5	0	13
Gamma-aminobutyric acid receptor subunit alpha-3	8	5	0	13
Gamma-aminobutyric acid receptor subunit gamma-1	8	5	0	13
Gamma-aminobutyric acid receptor subunit alpha-2	8	5	0	13
Gamma-aminobutyric acid receptor subunit alpha-4	8	5	0	13
Gamma-aminobutyric acid receptor subunit gamma-3	8	5	0	13
Gamma-aminobutyric acid receptor subunit alpha-6	8	5	0	13
Gamma-aminobutyric acid receptor subunit alpha-1	8	5	2	15
Gamma-aminobutyric acid receptor subunit beta-3	8	5	0	13
Gamma-aminobutyric acid receptor subunit beta-2	8	5	2	15
GABA theta subunit	8	5	0	13
Gamma-aminobutyric acid receptor subunit epsilon	8	5	0	13
Gamma-aminobutyric acid type B receptor subunit 1	0	2	2	4
Gamma-aminobutyric acid type B receptor subunit 1	0	2	0	2
Spike glycoprotein	0	0	1	1
Replicase polyprotein 1ab	0	0	1	1
Polyunsaturated fatty acid lipoxygenase ALOX15B	4	0	0	4
Transmembrane protease serine 2	0	0	1	1
5-hydroxytryptamine receptor 4	0	6	0	6
Procathepsin L	0	0	1	1
Aldo-keto reductase family 1 member B1	0	6	0	6
Muscarinic acetylcholine receptor M2	0	4	0	4
Muscarinic acetylcholine receptor M4	0	5	0	5
Muscarinic acetylcholine receptor M1	0	4	0	4
Muscarinic acetylcholine receptor M5	0	6	0	6
Alpha-2A adrenergic receptor	0	9	3	12
Replicase polyprotein 1a	0	0	1	1
Replicase polyprotein 1ab	0	0	1	1
Replicase polyprotein 1ab	0	2	1	3
Replicase polyprotein 1ab	0	2	2	4
Muscarinic acetylcholine receptor M2	0	4	0	4
Muscarinic acetylcholine receptor M1	0	5	1	6
Sodium-dependent noradrenaline transporter	0	9	1	10
Sodium-dependent dopamine transporter	0	3	0	3
Histamine H2 receptor	0	4	0	4
Sodium-dependent serotonin transporter	0	2	0	2
Histamine H2 receptor	6	0	0	7
Sigma non-opioid intracellular receptor 1	0	6	0	6
Angiotensin-converting enzyme 2	0	0	1	1
Proteasome subunit beta type-11	0	1	0	1
Calpain-9	0	1	0	1
Proteasome subunit alpha type-7	0	1	0	1
Cathepsin B	0	1	0	1
Aromatase	0	4	0	4
Indoleamine 2,3-dioxygenase 1	0	1	0	1
Calpain-2 catalytic subunit	0	1	0	1
Proteasome subunit beta type-1	0	2	0	2
Proteasome subunit alpha type-1	0	1	0	1
Proteasome subunit alpha type-2	0	1	0	1
Proteasome subunit alpha type-3	0	1	0	1
Proteasome subunit alpha type-4	0	1	0	1
NF-kappa-B inhibitor alpha	0	0	1	1
Proteasome subunit beta type-8	0	1	0	1
Proteasome subunit beta type-9	0	1	0	1
Proteasome subunit alpha type-5	0	1	0	1
Proteasome subunit beta type-4	0	1	0	1
Proteasome subunit beta type-6	0	1	0	1
Proteasome subunit beta type-5	0	2	0	2
Proteasome subunit beta type-10	0	1	0	1
Cathepsin K	0	1	0	1
Proteasome subunit beta type-3	0	1	0	1
Proteasome subunit beta type-2	0	2	0	2
Proteasome subunit alpha type-6	0	1	0	1
Proteasome subunit alpha-type 8	0	1	0	1
Proteasome subunit beta type-7	0	1	0	1
Gamma-secretase subunit PEN-2	0	1	0	1
Carbonic anhydrase 12	0	4	0	7
72 kDa type IV collagenase	0	1	0	1
Matrilysin	0	1	0	1
Prolyl 4-hydroxylase subunit alpha-1	0	1	0	1
Carbonic anhydrase 7	0	4	0	7
4-galactosyl-N-acetylglucosaminide 3-alpha-L-fucosyltransferase FUT6	0	1	0	1
Alpha-(1,3)-fucosyltransferase 7	0	1	0	1
CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 1	0	1	0	1
Carbonic anhydrase 9	0	4	0	7
Carbonic anhydrase 14	0	4	0	7
ORF73	0	0	2	2
Chain A, Betaine ABC transporter permease and substrate binding protein	0	0	1	1
Chain A, Osmoprotection protein (ProX)	0	0	1	1
Chain A, Glycine betaine/carnitine/choline-binding protein	0	0	2	2
Chain A, Glycine betaine/carnitine/choline-binding protein	0	0	2	2
Chain A, Glycine betaine/carnitine/choline-binding protein	0	0	2	2
Chain A, Glycine betaine/carnitine/choline-binding protein	0	0	2	2
Bile salt export pump	0	2	0	2
Chain A, Putative fructose-1,6-bisphosphate aldolase	2	0	0	2
Chain A, serum paraoxonase	0	1	0	1
Carbonic anhydrase 3	0	3	0	5
Neutrophil cytosol factor 1	0	1	0	1
Carbonic anhydrase 4	0	4	0	7
Carbonic anhydrase 6	0	3	0	6
Carbonic anhydrase 5A, mitochondrial	0	3	1	7
Carbonic anhydrase 13	0	3	0	3
Poly [ADP-ribose] polymerase tankyrase-2	0	1	0	1
Carbonic anhydrase 5B, mitochondrial	0	3	0	6
Solute carrier family 22 member 5	0	0	0	1
Solute carrier family 22 member 5	0	0	0	1
Solute carrier family 22 member 16	0	0	0	1
Solute carrier family 22 member 21	0	0	0	1
Solute carrier family 22 member 5	0	0	0	1
Chain A, Protein kinase CK2, alpha Subunit	0	1	0	1
Chain A, PROTEIN KINASE CK2, alpha SUBUNIT	0	1	0	1
Chain A, Protein Kinase Ck2, Alpha Subunit	0	1	0	1
endonuclease IV	2	0	0	2
Parkin	4	0	0	4
NPC intracellular cholesterol transporter 1 precursor	4	0	0	4
peripheral myelin protein 22 isoform 1	5	0	0	5
serine/threonine-protein kinase mTOR isoform 1	5	0	0	5
Serine/threonine-protein kinase Sgk1	0	1	0	1
Ribosyldihydronicotinamide dehydrogenase [quinone]	0	3	3	6
Casein kinase II subunit alpha	0	1	0	1
Casein kinase II subunit alpha'	0	2	1	3
D(1A) dopamine receptor	3	1	0	4
Casein kinase II subunit beta	0	2	0	2
Casein kinase II subunit beta	0	1	0	1
Casein kinase II subunit alpha	0	2	0	2
Cyclin-A1	0	1	0	1
Dual specificity mitogen-activated protein kinase kinase 1	0	1	1	2
Dual specificity tyrosine-phosphorylation-regulated kinase 1A	0	1	1	2
Ribosomal protein S6 kinase alpha-1	0	1	1	2
Casein kinase II subunit alpha 3	0	2	0	2
Single-stranded DNA cytosine deaminase	1	0	0	1
Luciferase	8	0	0	8
Vitamin D3 receptor	0	3	3	6
Retinoic acid receptor RXR-alpha	0	0	1	1
Ileal sodium/bile acid cotransporter	0	2	0	2
Bile acid receptor	0	0	1	1
G-protein coupled bile acid receptor 1	0	1	3	4
Bile acid receptor	0	0	3	3
Chain A, HADH2 protein	5	0	0	5
Chain B, HADH2 protein	5	0	0	5
15-lipoxygenase, partial	6	0	0	6
PINK1	2	0	0	2
bromodomain adjacent to zinc finger domain 2B	4	0	0	4
aryl hydrocarbon receptor	7	0	0	7
Histone H2A.x	6	0	0	6
serine-protein kinase ATM isoform a	2	0	0	2
prostaglandin E2 receptor EP2 subtype	0	0	0	1
Acetylcholinesterase	0	1	0	1
Carboxylic ester hydrolase	0	1	0	1
Rap guanine nucleotide exchange factor 4	4	0	0	4
Ubiquitin carboxyl-terminal hydrolase 2	0	1	0	1
Phospholipase A2	0	0	1	1
G-protein coupled bile acid receptor 1	0	1	0	1
Chain A, Acetylcholinesterase	0	0	1	1
Chain A, Acetylcholinesterase	0	0	1	1
Chain A, Acetylcholinesterase	0	0	1	1
Chain A, Acetylcholinesterase	0	0	1	1
Chain A, Acetylcholinesterase	0	0	1	1
Chain A, Acetylcholinesterase	0	0	1	1
Chain A, Acetylcholinesterase	0	0	1	1
Chain A, Putative Glycine Betaine-binding Abc Transporter Protein	0	0	1	1
Chain A, PUTATIVE GLYCINE BETAINE-BINDING ABC TRANSPORTER PROTEIN	0	0	1	1
Chain A, Choline-binding protein	0	0	1	1
Solute carrier family 22 member 1	0	1	0	2
Solute carrier family 22 member 1	0	2	0	3
Solute carrier family 22 member 2	0	1	0	1
Neuronal acetylcholine receptor subunit alpha-3	0	1	0	1
Neuronal acetylcholine receptor subunit alpha-2	0	1	0	1
Neuronal acetylcholine receptor subunit beta-3	0	1	0	1
Neuronal acetylcholine receptor subunit beta-4	0	1	0	1
Neuronal acetylcholine receptor subunit alpha-5	0	1	0	1
Acetylcholinesterase	0	6	1	7
Sodium- and chloride-dependent creatine transporter 1	0	1	0	1
Choline O-acetyltransferase	0	0	0	1
Neuronal acetylcholine receptor subunit alpha-6	0	1	0	1
Neuronal acetylcholine receptor subunit alpha-9	0	1	0	1
Neuronal acetylcholine receptor subunit alpha-7	0	3	0	3
Solute carrier family 22 member 1	0	1	0	2
High affinity choline transporter 1	0	1	0	1
Neuronal acetylcholine receptor subunit alpha-10	0	1	0	1
Solute carrier family 22 member 2	0	1	0	2
Sodium- and chloride-dependent creatine transporter 1	0	1	0	1
Ribonucleoside-diphosphate reductase large subunit	0	0	0	1
Ribonucleoside-diphosphate reductase subunit M2	0	0	0	1
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase	0	1	0	1
P2Y purinoceptor 6	0	0	1	1
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase	0	0	1	1
Ribonucleoside-diphosphate reductase subunit M2 B	0	0	0	1
Deoxycytidine kinase	0	0	0	1
Glutathione S-transferase P	0	1	0	1
Alpha-tocopherol transfer protein	0	0	1	1
Chain A, STEROID DELTA-ISOMERASE	0	0	1	1
Steroid Delta-isomerase	0	0	1	1
Synaptic vesicular amine transporter	0	3	1	4
Alpha-synuclein	3	1	0	4
UDP-glucuronosyltransferase 2B7	0	2	0	4
UDP-glucuronosyltransferase 1A1	0	1	0	2
UDP-glucuronosyltransferase 1A3	0	0	0	1
Sodium/bile acid cotransporter	0	1	0	1
NPC1-like intracellular cholesterol transporter 1	0	1	0	1
Nuclear receptor subfamily 1 group I member 2	0	1	3	4
Amine oxidase [flavin-containing] A	0	5	0	5
Amine oxidase [flavin-containing] B	0	4	1	5
Delta-type opioid receptor	0	3	0	3
Delta-type opioid receptor	0	4	0	4
Mu-type opioid receptor	0	4	1	5
Kappa-type opioid receptor	0	2	0	2
Mu-type opioid receptor	0	4	2	6
Delta-type opioid receptor	0	4	0	4
Kappa-type opioid receptor	0	3	0	3
Kappa-type opioid receptor	0	2	0	2
Mu-type opioid receptor	0	1	0	1
Mu-type opioid receptor	0	3	0	3
Sigma non-opioid intracellular receptor 1	0	5	0	5
Sigma non-opioid intracellular receptor 1	0	3	0	3
muscleblind-like protein 1 isoform 1	4	0	0	4
Gamma-aminobutyric acid receptor subunit pi	0	2	0	2
Gamma-aminobutyric acid receptor subunit delta	0	2	0	2
Gamma-aminobutyric acid receptor subunit alpha-1	0	2	0	3
Gamma-aminobutyric acid receptor subunit beta-1	0	2	0	3
Gamma-aminobutyric acid receptor subunit alpha-2	0	2	0	3
Gamma-aminobutyric acid receptor subunit alpha-3	0	2	0	3
Gamma-aminobutyric acid receptor subunit alpha-1	0	2	2	4
Gamma-aminobutyric acid receptor subunit beta-1	0	2	1	3
Gamma-aminobutyric acid receptor subunit gamma-2	0	2	2	4
Gamma-aminobutyric acid receptor subunit alpha-4	0	2	0	3
Gamma-aminobutyric acid receptor subunit gamma-2	0	2	0	3
Gamma-aminobutyric acid receptor subunit beta-3	0	2	2	4
Gamma-aminobutyric acid receptor subunit alpha-5	0	2	2	4
Gamma-aminobutyric acid receptor subunit alpha-3	0	2	2	4
Gamma-aminobutyric acid receptor subunit alpha-2	0	2	1	3
Gamma-aminobutyric acid receptor subunit beta-2	0	2	1	3
Gamma-aminobutyric acid receptor subunit alpha-4	0	2	1	3
Gamma-aminobutyric acid receptor subunit epsilon	0	2	0	2
Gamma-aminobutyric acid receptor subunit alpha-6	0	2	1	3
Gamma-aminobutyric acid receptor subunit gamma-1	0	2	0	2
Gamma-aminobutyric acid receptor subunit gamma-3	0	2	0	2
Gamma-aminobutyric acid receptor subunit theta	0	2	0	2
Chain A, Dihydrofolate reductase	0	0	1	1
Chain A, 2-oxoglutarate Oxygenase	5	0	0	5
DNA polymerase beta	3	0	0	3
Thymidylate synthase	0	2	0	2
Thymidylate synthase	0	1	0	1
Dihydrofolate reductase	0	0	1	1
Aldo-keto reductase family 1 member B1	0	1	0	1
Folylpolyglutamate synthase, mitochondrial	0	0	0	1
Solute carrier organic anion transporter family member 1A3	0	1	0	1
Folylpolyglutamate synthase, mitochondrial	0	0	0	1
Multidrug resistance associated protein	0	0	0	1
ubiquitin carboxyl-terminal hydrolase 2 isoform a	4	0	0	4
Voltage-dependent calcium channel subunit alpha-2/delta-1	0	1	0	1
Gamma-aminobutyric acid	0	0	1	1
Gamma-aminobutyric acid receptor subunit rho-3	0	0	1	1
Hsf1 protein	0	0	1	1
histone-lysine N-methyltransferase 2A isoform 2 precursor	3	0	0	3
Histone deacetylase 3	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-6	0	0	1	1
Gamma-aminobutyric acid receptor subunit gamma-2	0	0	1	1
Gamma-aminobutyric acid receptor subunit delta	0	0	1	1
Sodium- and chloride-dependent GABA transporter 1	0	2	0	2
Gamma-aminobutyric acid receptor subunit rho-1	0	0	2	2
Gamma-aminobutyric acid receptor subunit alpha-2	0	0	1	1
Gamma-aminobutyric acid receptor subunit alpha-3	0	0	1	1
Gamma-aminobutyric acid receptor subunit gamma-3	0	0	1	1
Gamma-aminobutyric acid receptor subunit rho-2	0	0	1	1
Sodium- and chloride-dependent GABA transporter 1	0	1	0	1
Sodium- and chloride-dependent taurine transporter	0	1	0	1
Sodium- and chloride-dependent GABA transporter 2	0	2	0	2
Sodium- and chloride-dependent GABA transporter 3	0	2	0	2
Sodium- and chloride-dependent GABA transporter 1	0	1	0	1
Sodium- and chloride-dependent GABA transporter 2	0	1	0	1
Sodium- and chloride-dependent GABA transporter 3	0	1	0	1
Sodium- and chloride-dependent betaine transporter	0	2	0	2
Sodium- and chloride-dependent betaine transporter	0	1	0	1
Sodium- and chloride-dependent GABA transporter 3	0	1	0	1
Gamma-aminobutyric acid receptor subunit beta-1	0	0	1	1
Histone deacetylase 4	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-1	0	0	1	1
Gamma-aminobutyric acid receptor subunit beta-3	0	0	1	1
4-aminobutyrate aminotransferase, mitochondrial	0	0	0	1
4-aminobutyrate aminotransferase, mitochondrial	0	0	0	1
Sterol O-acyltransferase 1	0	0	1	1
Gamma-aminobutyric acid receptor subunit alpha-5	0	0	1	1
Gamma-aminobutyric acid receptor subunit pi	0	0	1	1
Histone deacetylase 7	0	1	0	1
Polyamine deacetylase HDAC10	0	1	0	1
Histone deacetylase 11	0	1	0	1
Histone deacetylase 8	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-4	0	0	1	1
Platelet glycoprotein VI	0	0	1	1
Gamma-aminobutyric acid receptor subunit theta	0	0	1	1
Sodium- and chloride-dependent GABA transporter 2	0	1	0	1
Gamma-aminobutyric acid receptor subunit gamma-1	0	0	1	1
Histone deacetylase 9	0	1	0	1
Histone deacetylase 5	0	1	0	1
Chain A, GLUTAMATE RECEPTOR SUBUNIT 2	0	1	0	1
Chain A, Glutamate Receptor Subunit 2	0	1	0	1
Chain B, Glutamate Receptor Subunit 2	0	1	0	1
Chain A, Slr1257 protein	0	0	1	1
Chain A, Glucosamine--fructose-6-phosphate aminotransferase [isomerizing]	0	1	0	1
beta-2 adrenergic receptor	2	0	0	2
Metabotropic glutamate receptor 8	0	2	0	2
Glutamate receptor ionotropic, NMDA 2D	0	1	0	1
Glutamate receptor ionotropic, NMDA 3B	0	1	0	1
Glutathione reductase, mitochondrial	0	4	0	4
Bifunctional aspartokinase/homoserine dehydrogenase 1	0	1	0	1
Prothrombin	0	0	1	1
Integrin alpha-IIb	1	0	1	2
ATP-citrate synthase	0	1	0	1
Glutamate receptor 1	0	2	1	3
Glutamate receptor 3	0	2	1	3
Glutamate receptor 4	0	2	1	3
Glutamate receptor ionotropic, kainate 1	0	2	1	3
Metabotropic glutamate receptor 1	0	1	1	2
Metabotropic glutamate receptor 2	0	0	1	1
Metabotropic glutamate receptor 3	0	0	1	1
Metabotropic glutamate receptor 4	0	1	1	2
Metabotropic glutamate receptor 5	0	0	1	1
Metabotropic glutamate receptor 6	0	0	1	1
Metabotropic glutamate receptor 7	0	0	1	1
Glutamate receptor ionotropic, kainate 1	0	1	1	2
Metabotropic glutamate receptor 5	0	1	1	3
Glutamate receptor ionotropic, kainate 2	0	2	1	3
Glutamate receptor 1	0	2	1	3
Glutamate receptor 2	0	2	1	3
Glutamate receptor 3	0	1	1	2
Glutamate receptor ionotropic, kainate 3	0	2	0	2
Metabotropic glutamate receptor 8	0	0	1	1
Glutamate receptor 4	0	2	1	3
Excitatory amino acid transporter 3	0	0	0	1
Glutamate racemase	0	0	0	1
Metabotropic glutamate receptor 8	0	1	1	2
Glutamate receptor ionotropic, kainate 4	0	2	0	2
Glutamate carboxypeptidase 2	0	1	0	1
Glutamate receptor ionotropic, kainate 2	0	1	1	2
Glutamate receptor ionotropic, kainate 3	0	1	0	1
Metabotropic glutamate receptor 7	0	1	1	3
Metabotropic glutamate receptor 3	0	1	1	3
Metabotropic glutamate receptor 4	0	1	1	3
Glutamate receptor ionotropic, NMDA 2C	0	1	0	1
Glutamate receptor ionotropic, kainate 5	0	1	0	1
Glutamate receptor ionotropic, kainate 5	0	2	0	2
Glutamate racemase	0	0	0	1
Prolyl 4-hydroxylase	0	1	0	1
Glutamate receptor ionotropic, NMDA 3A	0	1	0	1
Alpha-ketoglutarate-dependent dioxygenase FTO	0	1	0	1
Chain A, Glutamine Binding Protein	0	0	1	1
Asc-type amino acid transporter 1	0	1	0	1
Chain B, EUKARYOTIC TRANSLATION INITIATION FACTOR 4E	0	0	1	1
Purine nucleoside phosphorylase	0	2	0	2
Hypoxanthine-guanine phosphoribosyltransferase	0	0	0	1
Ricin	0	1	0	1
2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase	0	0	1	1
Purine nucleoside phosphorylase	0	0	1	2
Shiga toxin subunit A	0	1	0	1
Guanine deaminase	0	0	0	1
Chain A, Uracil Phosphoribosyltransferase	0	0	1	1
Chain B, Uracil Phosphoribosyltransferase	0	0	1	1
Chain C, Uracil Phosphoribosyltransferase	0	0	1	1
2-dehydropantoate 2-reductase	0	0	1	1
Ras-related protein Rab-7a	0	0	1	1
4-galactosyl-N-acetylglucosaminide 3-alpha-L-fucosyltransferase 9	0	2	0	2
Chain A, ATP-DEPENDENT DNA HELICASE Q1	2	0	0	2
tyrosine-protein kinase Yes	1	0	0	1
Plasma kallikrein	0	0	1	3
Retinoic acid receptor RXR-alpha	0	0	1	1
Adenylate cyclase type 1	0	1	0	1
cytochrome P450 2C9 precursor	3	0	0	3
transient receptor potential cation channel subfamily V member 1	1	0	0	1
Cocaine esterase	0	1	0	1
Transient receptor potential cation channel subfamily V member 1	0	1	0	1
Voltage-dependent L-type calcium channel subunit alpha-1C	0	1	0	1
UDP-glucuronosyltransferase 1A9	0	1	0	2
Voltage-dependent L-type calcium channel subunit alpha-1F	0	1	0	1
Albumin	0	0	1	1
Major prion protein	0	0	2	2
Vitamin D-binding protein	0	1	0	1
HLA class I histocompatibility antigen, A alpha chain	0	0	1	1
Integrin beta-1	0	1	0	1
Muscarinic acetylcholine receptor M3	0	3	0	3
Muscarinic acetylcholine receptor M4	0	3	0	3
Muscarinic acetylcholine receptor M5	0	3	0	3
Beta-2 adrenergic receptor	0	2	0	2
Cytochrome P450 2C9	0	3	0	3
Angiotensin-converting enzyme	0	2	0	2
Integrin alpha-4	0	1	0	1
Carbonyl reductase [NADPH] 1	0	0	0	1
Beta-1 adrenergic receptor	0	2	0	2
D(3) dopamine receptor	0	3	0	3
Alpha-2B adrenergic receptor	0	3	0	3
D(2) dopamine receptor	0	2	0	2
Adenylate cyclase type 3	0	1	0	1
Alpha-2C adrenergic receptor	0	3	0	3
UDP-glucuronosyltransferase 1A4	0	1	0	3
Alpha-2A adrenergic receptor	0	3	0	3
5-hydroxytryptamine receptor 3A	0	1	0	1
Adenosine receptor A1	0	3	0	5
D(1B) dopamine receptor	0	2	0	2
Beta-3 adrenergic receptor	0	1	0	1
Adenylate cyclase type 2	0	1	0	1
Adenylate cyclase type 4	0	1	0	1
5-hydroxytryptamine receptor 1B	0	1	0	1
5-hydroxytryptamine receptor 1D	0	1	0	1
5-hydroxytryptamine receptor 1F	0	1	0	1
5-hydroxytryptamine receptor 2B	0	4	0	4
Histamine H1 receptor	0	2	0	2
C-8 sterol isomerase	0	1	0	1
5-hydroxytryptamine receptor 2C	0	1	0	1
5-hydroxytryptamine receptor 2A	0	1	0	1
Sodium channel protein type 1 subunit alpha	0	1	0	1
Sodium channel protein type 4 subunit alpha	0	1	0	1
Adenylate cyclase type 8	0	1	0	1
5-hydroxytryptamine receptor 2A	0	1	0	1
5-hydroxytryptamine receptor 7	0	1	0	1
Cytochrome P450 2J2	0	1	0	1
D(2) dopamine receptor	0	1	0	1
D(3) dopamine receptor	0	1	0	1
Gastrin/cholecystokinin type B receptor	0	1	0	1
AP-2 complex subunit sigma	0	1	0	1
N-acetyltransferase Eis	0	2	0	2
Sodium channel protein type 7 subunit alpha	0	1	0	1
Voltage-dependent L-type calcium channel subunit alpha-1D	0	1	0	1
5-hydroxytryptamine receptor 2B	0	1	0	1
Adenylate cyclase type 6	0	1	0	1
Adenylate cyclase type 5	0	1	0	1
5-hydroxytryptamine receptor 4	0	1	0	1
Voltage-dependent L-type calcium channel subunit alpha-1S	0	1	0	1
Voltage-dependent L-type calcium channel subunit alpha-1C	0	1	0	1
Sodium channel protein type 5 subunit alpha	0	1	0	1
3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase	0	1	0	1
Sodium channel protein type 9 subunit alpha	0	1	0	1
Calcitonin gene-related peptide type 1 receptor	0	1	0	1
Genome polyprotein	0	2	0	2
Sigma intracellular receptor 2	0	1	0	1
Sigma intracellular receptor 2	0	2	0	2
Zinc finger protein 664	0	1	0	1
Vesicular acetylcholine transporter	0	1	0	1
Transporter	0	2	0	2
Cholecystokinin receptor type A	0	1	0	1
Protease	0	2	0	2
Adenylyl cyclase 7	0	1	0	1
D	0	1	0	1
Sodium channel protein type 2 subunit alpha	0	1	0	1
Transient receptor potential cation channel subfamily V member 4	0	1	0	1
Sodium channel protein type 3 subunit alpha	0	1	0	1
Sodium channel protein type 11 subunit alpha	0	1	0	1
Sodium channel protein type 8 subunit alpha	0	1	0	1
Transient receptor potential cation channel subfamily V member 2	0	2	0	2
Sodium channel protein type 10 subunit alpha	0	1	0	1
N(G),N(G)-dimethylarginine dimethylaminohydrolase 1	0	1	0	1
Chain B, Pulmonary surfactant-associated protein D	0	1	0	1
Chain A, Pulmonary surfactant-associated protein D	0	1	0	1
parathyroid hormone/parathyroid hormone-related peptide receptor precursor	3	0	0	3
Amyloid-beta precursor protein	0	2	1	3
Sodium/myo-inositol cotransporter 2	0	1	0	1
Chain A, BETA-SPECTRIN	0	0	1	1
Chain A, Phospholipase C Delta-1	0	0	1	1
Chain A, Inositol 1,4,5-trisphosphate receptor type 1	0	0	1	1
Inositol-trisphosphate 3-kinase A	0	1	0	1
Inositol 1,4,5-trisphosphate receptor type 1	0	0	2	2
Inositol 1,4,5-trisphosphate receptor type 2	0	1	0	1
Inositol 1,4,5-trisphosphate receptor type 3	0	1	1	2
Inositol polyphosphate-5-phosphatase A	0	1	0	1
Inositol 1,4,5-trisphosphate receptor type 1	0	1	1	2
Carbonic anhydrase	0	2	0	4
Carbonic anhydrase 15	0	3	0	5
atrial natriuretic peptide receptor 1 precursor	3	0	0	3
Acetylcholinesterase	0	4	0	4
Acetylcholinesterase	0	0	1	1
Lysosomal protective protein	0	1	0	1
Fatty acid synthase	0	1	0	1
Liver carboxylesterase	0	1	0	1
Large neutral amino acids transporter small subunit 1	0	5	0	5
Chain A, AMINOPEPTIDASE	0	1	0	1
Chain A, AMINOPEPTIDASE	0	1	0	1
Chain A, Leucine Aminopeptidase	0	1	0	1
Alkaline phosphatase, tissue-nonspecific isozyme	0	1	0	1
Intestinal-type alkaline phosphatase	0	1	0	1
Phospholipase A-2-activating protein	0	1	0	1
WRN	1	0	0	1
integrase, partial	0	1	0	1
lens epithelium-derived growth factor p75	0	1	0	1
apical membrane antigen 1, AMA1	1	0	0	1
pyruvate kinase	2	0	0	2
hexokinase-4 isoform 1	3	0	0	3
glucokinase regulatory protein	3	0	0	3
M-phase phosphoprotein 8	2	0	0	2
Epidermal growth factor receptor	0	2	1	3
Polyunsaturated fatty acid lipoxygenase ALOX15	0	2	0	2
Adenosine receptor A2a	0	0	0	2
Solute carrier family 15 member 1	0	1	0	1
Carbonic anhydrase	0	1	0	3
SLC16A10 protein	0	0	0	2
Carbonic anhydrase	0	1	0	3
Carbonic anhydrase	0	1	0	3
Carbonic anhydrase	0	1	0	3
Carbonic anhydrase	0	1	0	3
Monocarboxylate transporter 10	0	0	0	2
Carbonic anhydrase 13	0	1	0	3
phosphoglycerate kinase	1	0	0	1
Chain A, Ribulose-1,5 bisphosphate carboxylase/oxygenase large subunit N-methyltransferase, chloroplast	0	1	0	1
Chain A, Ribulose-1,5 bisphosphate carboxylase/oxygenase large subunit N-methyltransferase, chloroplast	0	1	0	1
nuclear receptor subfamily 1, group I, member 2	3	0	0	3
Glucocorticoid receptor	0	2	0	2
Glycine receptor subunit alpha-1	0	2	0	2
Androgen receptor	0	2	0	2
Glycine receptor subunit beta	0	2	0	2
Glycine receptor subunit alpha-2	0	2	0	2
Glycine receptor subunit alpha-3	0	2	0	2
Nuclear receptor subfamily 1 group I member 2	0	0	1	1
Beta-galactosidase	0	1	0	1
Beta-galactosidase	0	2	0	2
Alpha-galactosidase	0	2	0	2
Beta-galactosidase	0	1	0	1
Beta-galactosidase	0	1	0	1
Alpha-galactosidase C	0	1	0	1
Solute carrier family 22 member 20	0	1	0	1
Solute carrier family 22 member 6	0	1	0	1
Chain B, Exotoxin A	0	0	1	1
Chain B, Exotoxin A	0	0	1	1
Chain B, Exotoxin A	0	0	1	1
Chain A, Glutathione-requiring prostaglandin D synthase	0	1	0	1
nuclear receptor subfamily 0 group B member 1	0	1	0	1
cellular tumor antigen p53 isoform a	2	0	0	2
histone deacetylase 9 isoform 3	3	0	0	3
huntingtin isoform 2	2	0	0	2
atrial natriuretic peptide receptor 2 precursor	3	0	0	3
steroidogenic factor 1	0	1	0	1
Tyrosine-protein kinase ABL1	0	3	1	5
Tubulin alpha-1A chain	0	1	1	3
Tubulin beta chain	0	1	1	2
Tubulin beta-4A chain	0	2	2	5
Tubulin beta chain	0	2	2	5
Tubulin alpha-3C chain	0	2	2	5
Adenosine receptor A2a	0	2	0	2
Adenosine receptor A1	0	2	0	2
Tubulin alpha-1B chain	0	2	2	5
Tubulin alpha-4A chain	0	2	2	5
Tubulin beta-4B chain	0	2	2	5
Tubulin beta-3 chain	0	3	2	6
Tubulin beta-2A chain	0	2	2	5
Tubulin beta-8 chain	0	2	2	5
Tubulin beta-2B chain	0	2	1	6
Tubulin alpha-3E chain	0	2	2	5
Tubulin alpha-1A chain	0	2	2	5
Similar to alpha-tubulin isoform 1	0	2	1	6
Similar to alpha-tubulin isoform 1	0	2	0	5
CREB-binding protein	2	0	0	2
Tubulin alpha-1C chain	0	2	2	5
Tubulin beta-6 chain	0	2	2	5
Tubulin beta-2B chain	0	2	2	5
Tubulin beta-1 chain	0	2	2	5
Fatty-acid amide hydrolase 1	0	1	0	1
Muscarinic acetylcholine receptor DM1	0	1	0	1
Acetylcholinesterase	0	1	0	1
Cannabinoid receptor 1	0	2	0	2
FAD-linked sulfhydryl oxidase ALR	0	0	0	2
Glucose-6-phosphate 1-dehydrogenase	0	1	0	1
Disintegrin and metalloproteinase domain-containing protein 17	2	0	0	2
Nuclear receptor subfamily 3 group C member 3	0	1	0	1
Transporter	0	1	0	1
Chain A, Adipocyte Lipid-binding Protein	0	0	1	1
Chain A, SERUM ALBUMIN	0	0	1	1
Chain A, SERUM ALBUMIN	0	0	1	1
Chain A, MUSCLE FATTY ACID BINDING PROTEIN	0	0	1	1
Chain A, MUSCLE FATTY ACID BINDING PROTEIN	0	0	1	1
Chain A, MUSCLE FATTY ACID BINDING PROTEIN	0	0	1	1
Chain A, BCL-2-RELATED PROTEIN A1	0	0	1	1
putative potassium channel subunit	0	0	1	1
bcl-2-like protein 11 isoform 1	0	0	1	1
Prostaglandin G/H synthase 1	0	1	0	1
Sterol O-acyltransferase 1	0	1	0	1
Trypsin	0	1	0	1
Fatty acid-binding protein, liver	0	1	0	1
Fatty acid-binding protein, liver	0	0	1	1
Seed linoleate 13S-lipoxygenase-1	0	1	0	1
Coagulation factor VII	0	1	0	1
DNA topoisomerase 1	0	1	0	1
Tissue factor	0	1	0	1
Protein kinase C alpha type	0	0	2	3
Tyrosine-protein phosphatase non-receptor type 1	0	2	0	2
Sterol O-acyltransferase 1	0	1	0	1
Nuclear receptor subfamily 4 group A member 2	0	0	2	2
Prostaglandin G/H synthase 2	0	2	0	2
Peroxisome proliferator-activated receptor delta	0	0	0	1
Peroxisome proliferator-activated receptor alpha	1	0	1	2
Chain A, ARGINASE 1	0	1	0	1
Chain A, Arginase 1	0	1	0	1
Chain A, ARGINASE 1	0	1	0	1
Chain A, L-ARGININE\\:GLYCINE AMIDINOTRANSFERASE	0	1	0	1
Chain A, Beta-lactamase	4	0	0	4
Genome polyprotein	0	1	0	1
pregnane X receptor	2	0	0	2
Receptor tyrosine-protein kinase erbB-2	0	1	0	1
60 kDa chaperonin	0	1	0	1
Botulinum neurotoxin type A	0	1	0	1
Apoptosis regulator Bcl-2	0	1	0	1
60 kDa heat shock protein, mitochondrial	0	1	0	1
Fibroblast growth factor receptor 1	0	1	1	2
Proto-oncogene tyrosine-protein kinase Src	0	1	1	2
UDP-glucuronosyltransferase 1-6	0	1	0	1
ATP-dependent translocase ABCB1	0	1	0	1
Substance-K receptor	0	2	0	2
Serum paraoxonase/arylesterase 1	0	1	0	1
Cholecystokinin receptor type A	0	2	0	2
Melanocortin receptor 5	0	2	0	2
UDP-glucuronosyltransferase 2B10	0	1	0	1
10 kDa heat shock protein, mitochondrial	0	1	0	1
Bcl-2-like protein 1	0	2	0	2
Tyrosine-protein kinase Mer	0	1	1	2
Thiosulfate sulfurtransferase	0	1	0	1
Beta-tubulin	0	1	0	1
60 kDa chaperonin	0	1	0	1
10 kDa chaperonin	0	1	0	1
Nucleotide-binding oligomerization domain-containing protein 2	0	1	0	1
Chain A, cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A	0	1	0	1
cGMP-dependent 3',5'-cyclic phosphodiesterase	0	1	0	1
High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8A	0	1	0	1
cGMP-specific 3',5'-cyclic phosphodiesterase	0	1	0	1
3',5'-cyclic-AMP phosphodiesterase	0	1	0	1
Vascular endothelial growth factor receptor 1	0	1	0	1
cAMP-specific 3',5'-cyclic phosphodiesterase 4A	0	1	0	1
Cytochrome P450 2C19	0	4	0	4
Serine hydroxymethyltransferase, mitochondrial	0	1	0	1
Vascular endothelial growth factor receptor 3	0	1	0	1
Vascular endothelial growth factor receptor 2	0	1	0	1
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A	0	1	0	1
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B	0	1	0	1
cAMP-specific 3',5'-cyclic phosphodiesterase 4D	0	1	0	1
cGMP-inhibited 3',5'-cyclic phosphodiesterase B	0	2	0	2
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C	0	1	0	1
cGMP-inhibited 3',5'-cyclic phosphodiesterase A	0	2	0	2
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A	0	2	0	2
Phosphodiesterase	0	1	0	1
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A	0	1	0	2
Mcl-1	0	1	0	1
Alpha-1B adrenergic receptor	0	0	1	1
Beta-2 adrenergic receptor	0	0	1	1
Beta-1 adrenergic receptor	0	0	1	1
Beta-3 adrenergic receptor	0	0	1	1
Alpha-1A adrenergic receptor	0	1	1	2
Alpha-1B adrenergic receptor	0	1	0	1
Alpha-2B adrenergic receptor	0	0	0	1
Alpha-2C adrenergic receptor	0	0	0	1
Alpha-2A adrenergic receptor	0	0	0	1
GALC protein	1	0	0	1
Vpr	1	0	0	1
Glutamate 5-kinase	0	0	0	1
Angiotensin-converting enzyme	0	1	0	1
Chain A, Troponin C, slow skeletal and cardiac muscles	0	0	1	1
Chain A, Leukotriene A-4 hydrolase	0	1	0	1
Chain A, Leukotriene A-4 hydrolase	0	1	0	1
Chain A, Leukotriene A-4 hydrolase	0	1	0	1
Chain A, Leukotriene A-4 hydrolase	0	1	0	1
Chain A, Leukotriene A-4 hydrolase	0	1	0	1
Chain A, Leukotriene A-4 hydrolase	0	1	0	1
Chain A, Leukotriene A-4 hydrolase	0	1	0	1
Chain A, Leukotriene A-4 hydrolase	0	1	0	1
Chain A, Leukotriene A-4 hydrolase	0	1	0	1
Chain A, Leukotriene A-4 hydrolase	0	1	0	1
Chain A, Leukotriene A-4 hydrolase	0	1	0	1
Chain A, Leukotriene A-4 hydrolase	0	1	0	1
Chain A, Leukotriene A-4 hydrolase	0	1	0	1
Chain A, Leukotriene A-4 hydrolase	0	1	0	1
Chain A, Leukotriene A-4 hydrolase	0	1	0	1
Chain A, Leukotriene A-4 hydrolase	0	1	0	1
Chain A, Leukotriene A-4 hydrolase	0	1	0	1
BRCA1	1	0	0	1
ClpP	1	0	0	1
P53	1	0	0	1
M18 aspartyl aminopeptidase	0	1	0	1
cathepsin L1	0	1	0	1
nuclear factor NF-kappa-B p105 subunit isoform 1	0	0	1	1
Vif	0	1	0	1
DNA dC->dU-editing enzyme APOBEC-3G isoform 1	1	1	0	2
transcription factor p65 isoform 1	0	0	1	1
serine/threonine-protein kinase 33 isoform a	0	0	1	1
POsterior Segregation	0	0	1	1
Aryl hydrocarbon receptor	0	1	0	1
Estrogen receptor beta	0	0	1	1
Lysine-specific histone demethylase 1A	0	1	0	1
Myc proto-oncogene protein	0	1	0	2
Estrogen receptor	0	1	0	1
Cytochrome P450 1A1	0	1	0	1
Cytochrome P450 1A2	0	1	0	1
Prostaglandin G/H synthase 1	0	1	1	2
Cholinesterase	0	2	0	2
Cathepsin D	0	1	0	1
Luciferin 4-monooxygenase	0	1	0	1
DNA polymerase alpha catalytic subunit	0	1	0	1
Polyunsaturated fatty acid 5-lipoxygenase	0	2	0	2
Leukotriene A-4 hydrolase	0	1	0	1
Breakpoint cluster region protein	0	1	1	3
Tyrosinase	0	2	0	2
Ornithine decarboxylase	0	1	0	1
Estrogen receptor	0	0	1	1
Nuclear factor NF-kappa-B p105 subunit	0	1	0	1
Endothelin receptor type B	1	0	0	1
Prostaglandin G/H synthase 1	0	1	0	1
Endothelin-1 receptor	1	0	0	1
Dipeptidyl peptidase 4	0	1	0	1
ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1	0	1	0	1
Cholinesterase	0	2	0	2
Nuclear factor NF-kappa-B p100 subunit	0	1	0	1
Squalene synthase	0	1	0	1
Transcription factor p65	0	1	0	1
cAMP-specific 3',5'-cyclic phosphodiesterase 4B	0	0	0	1
Serine/threonine-protein kinase PAK 1	0	1	0	1
Nuclear factor erythroid 2-related factor 2	0	0	1	2
Cytochrome P450 1B1	0	2	0	2
N1L	0	1	0	1
NAD(P)H dehydrogenase [quinone] 1	0	0	0	2
Transient receptor potential cation channel subfamily A member 1	0	1	0	1
NAD-dependent protein deacetylase sirtuin-2	0	0	1	1
NAD-dependent protein deacetylase sirtuin-1	0	0	1	3
Prenyltransferase homolog	0	0	0	1
NAD-dependent protein deacetylase sirtuin-3, mitochondrial	0	0	1	1
Zinc finger protein mex-5	0	0	1	1
large T antigen	0	1	0	1
Potassium channel subfamily K member 3	0	1	0	1
Met repressor	0	0	2	2
Protein arginine N-methyltransferase 5	0	0	1	1
Histone H3K27 methylase	0	0	0	1
Phenylethanolamine N-methyltransferase	0	0	1	2
S-adenosylmethionine decarboxylase proenzyme	0	1	0	2
Protein-L-isoaspartate(D-aspartate) O-methyltransferase	0	1	0	1
Catechol O-methyltransferase	0	0	0	1
Protein arginine N-methyltransferase 1	0	1	0	1
Methylosome protein 50	0	0	1	1
Cytochrome P450 2B1	0	1	0	1
Amine oxidase [flavin-containing] B	0	2	0	3
Amine oxidase [flavin-containing] A	0	2	0	3
Amine oxidase [flavin-containing] A	0	2	0	2
Type-1 angiotensin II receptor	0	1	0	1
C-X-C chemokine receptor type 3	0	1	0	1
Amine oxidase [flavin-containing] B	0	2	0	2
Amine oxidase [flavin-containing] A	0	0	0	1
Amine oxidase [flavin-containing] B	0	0	0	1
Pyruvate kinase PKM	0	0	1	1
photoreceptor-specific nuclear receptor	0	1	0	1
transactivating tegument protein VP16 [Human herpesvirus 1]	0	1	0	1
3-hydroxy-3-methylglutaryl-coenzyme A reductase	0	1	0	1
Bone morphogenetic protein receptor type-1B	0	0	1	1
Cell division cycle 7-related protein kinase	0	0	1	1
Serine/threonine-protein kinase PLK4	0	0	1	1
ATP-dependent RNA helicase DDX3X	0	0	1	1
Pyridoxal kinase	0	0	1	1
Citron Rho-interacting kinase	0	0	1	1
Serine/threonine-protein kinase Chk1	0	0	1	1
Aurora kinase A	0	0	1	1
Cyclin-G-associated kinase	0	0	1	1
Ephrin type-B receptor 6	0	0	1	1
Peroxisomal acyl-coenzyme A oxidase 3	0	0	1	1
Receptor-interacting serine/threonine-protein kinase 2	0	0	1	1
Mitotic checkpoint serine/threonine-protein kinase BUB1	0	0	1	1
Dynamin-like 120 kDa protein, mitochondrial	0	0	1	1
Tyrosine-protein kinase JAK2	0	0	1	1
Eukaryotic translation initiation factor 5B	0	0	1	1
Rho-associated protein kinase 2	0	0	1	1
Serine/threonine-protein kinase ULK1	0	0	1	1
Serine/threonine-protein kinase/endoribonuclease IRE1	0	0	1	1
Ribosomal protein S6 kinase alpha-5	0	0	1	1
U5 small nuclear ribonucleoprotein 200 kDa helicase	0	0	1	1
Ribosomal protein S6 kinase alpha-4	0	0	1	1
Serine/threonine-protein kinase 16	0	0	1	1
Cyclin-dependent kinase-like 5	0	0	1	1
Serine/threonine-protein kinase 10	0	0	1	1
Serine/threonine-protein kinase D3	0	0	1	1
Structural maintenance of chromosomes protein 2	0	0	1	1
Mitogen-activated protein kinase kinase kinase 6	0	0	1	1
Mitogen-activated protein kinase kinase kinase kinase 4	0	0	1	1
Serine/threonine-protein kinase LATS1	0	0	1	1
Serine/threonine-protein kinase PAK 4	0	0	1	1
Sarcoplasmic/endoplasmic reticulum calcium ATPase 1	0	1	0	1
High affinity nerve growth factor receptor	0	0	1	1
ADP/ATP translocase 2	0	0	1	1
Protein kinase C beta type	0	0	1	1
Insulin receptor	0	0	1	1
Eukaryotic translation initiation factor 4E	0	0	1	1
Glycogen phosphorylase, liver form	0	0	1	1
Tyrosine-protein kinase Fes/Fps	0	0	1	1
Adenine phosphoribosyltransferase	0	0	1	1
Tyrosine-protein kinase Yes	0	0	1	1
Tyrosine-protein kinase Lyn	0	0	1	1
Proto-oncogene tyrosine-protein kinase receptor Ret	0	0	1	1
Insulin-like growth factor 1 receptor	0	0	1	1
Signal recognition particle receptor subunit alpha	0	0	1	1
Cytochrome c1, heme protein, mitochondrial	0	0	1	1
Hepatocyte growth factor receptor	0	0	1	1
Tyrosine-protein kinase HCK	0	0	1	1
Platelet-derived growth factor receptor beta	0	0	1	1
Tyrosine-protein kinase Fgr	0	0	1	1
Serine/threonine-protein kinase A-Raf	0	0	1	1
Glycogen phosphorylase, brain form	0	0	1	1
Serine/threonine-protein kinase pim-1	0	0	1	1
DNA topoisomerase 2-alpha	0	0	1	1
Cyclin-dependent kinase 4	0	0	1	1
ADP/ATP translocase 3	0	0	1	1
Inosine-5'-monophosphate dehydrogenase 2	0	0	1	1
cAMP-dependent protein kinase type II-alpha regulatory subunit	0	0	1	1
Serine/threonine-protein kinase B-raf	0	0	1	1
Phosphorylase b kinase gamma catalytic chain, liver/testis isoform	0	0	1	1
Tyrosine-protein kinase Fer	0	0	1	1
cAMP-dependent protein kinase catalytic subunit alpha	0	0	1	1
General transcription and DNA repair factor IIH helicase subunit XPD	0	0	1	1
Ras-related protein Rab-6A	0	0	1	1
Ephrin type-A receptor 1	0	0	1	1
Multifunctional protein ADE2	0	0	1	1
cAMP-dependent protein kinase catalytic subunit beta	0	0	1	1
Ferrochelatase, mitochondrial	0	0	1	1
Ribosomal protein S6 kinase beta-1	0	0	1	1
Tyrosine-protein kinase JAK1	0	0	1	1
Beta-adrenergic receptor kinase 1	0	0	1	1
Probable ATP-dependent RNA helicase DDX6	0	0	1	1
Peptidyl-prolyl cis-trans isomerase FKBP1A	0	1	0	1
Mitogen-activated protein kinase 3	0	0	1	1
MAP/microtubule affinity-regulating kinase 3	0	0	1	1
Deoxycytidine kinase	0	0	1	1
Mitogen-activated protein kinase 1	0	0	1	1
Ephrin type-A receptor 2	0	0	1	1
Ephrin type-B receptor 2	0	0	1	1
Non-receptor tyrosine-protein kinase TYK2	0	0	1	1
UMP-CMP kinase	0	0	1	1
Phosphatidylethanolamine-binding protein 1	0	0	1	1
Wee1-like protein kinase	0	0	1	1
Heme oxygenase 2	0	0	1	1
S-adenosylmethionine synthase isoform type-2	0	0	1	1
DnaJ homolog subfamily A member 1	0	0	1	1
RAC-alpha serine/threonine-protein kinase	0	0	1	1
RAC-beta serine/threonine-protein kinase	0	0	1	1
Dual specificity protein kinase TTK	0	0	1	1
DNA replication licensing factor MCM4	0	0	1	1
Myosin-10	0	0	1	1
Dual specificity mitogen-activated protein kinase kinase 2	0	0	1	1
Receptor-type tyrosine-protein kinase FLT3	0	0	1	1
Bone morphogenetic protein receptor type-1A	0	0	1	1
Activin receptor type-1B	0	0	1	1
TGF-beta receptor type-1	0	0	1	1
Serine/threonine-protein kinase receptor R3	0	0	1	1
TGF-beta receptor type-2	0	0	1	1
Electron transfer flavoprotein subunit beta	0	0	1	1
Tyrosine-protein kinase CSK	0	0	1	1
Glycine--tRNA ligase	0	0	1	1
Protein kinase C iota type	0	0	1	1
Exosome RNA helicase MTR4	0	0	1	1
Serine/threonine-protein kinase mTOR	0	1	1	2
Tyrosine-protein kinase Tec	0	0	1	1
Tyrosine-protein kinase ABL2	0	0	1	1
Tyrosine-protein kinase FRK	0	0	1	1
G protein-coupled receptor kinase 6	0	0	1	1
Tyrosine-protein kinase SYK	0	0	1	1
26S proteasome regulatory subunit 6B	0	0	1	1
Mitogen-activated protein kinase 8	0	0	1	1
Mitogen-activated protein kinase 9	0	0	1	1
Dual specificity mitogen-activated protein kinase kinase 3	0	0	1	1
Phosphatidylinositol 5-phosphate 4-kinase type-2 alpha	0	0	1	1
Casein kinase I isoform alpha	0	0	1	1
Casein kinase I isoform delta	0	0	1	1
MAP kinase-activated protein kinase 2	0	0	1	1
Elongation factor Tu, mitochondrial	0	0	1	1
Choline-phosphate cytidylyltransferase A	0	0	1	1
Cysteine--tRNA ligase, cytoplasmic	0	0	1	1
Casein kinase I isoform epsilon	0	0	1	1
Very long-chain specific acyl-CoA dehydrogenase, mitochondrial	0	0	1	1
Dual specificity protein kinase CLK1	0	0	1	1
Dual specificity protein kinase CLK2	0	0	1	1
Dual specificity protein kinase CLK3	0	0	1	1
Glycogen synthase kinase-3 alpha	0	0	1	1
Glycogen synthase kinase-3 beta	0	0	1	1
Cyclin-dependent kinase 7	0	0	1	1
Cyclin-dependent kinase 9	0	0	1	1
Ras-related protein Rab-27A	0	0	1	1
Interleukin-1 receptor-associated kinase 1	0	0	1	1
Ribosomal protein S6 kinase alpha-3	0	0	1	1
Serine/threonine-protein kinase Nek2	0	0	1	1
Serine/threonine-protein kinase Nek3	0	0	1	1
Dual specificity mitogen-activated protein kinase kinase 6	0	0	1	1
Serine/threonine-protein kinase PLK1	0	0	1	1
LIM domain kinase 1	0	0	1	1
LIM domain kinase 2	0	0	1	1
Mitogen-activated protein kinase 10	0	0	1	1
Tyrosine--tRNA ligase, cytoplasmic	0	0	1	1
5'-AMP-activated protein kinase subunit gamma-1	0	0	1	1
Ephrin type-B receptor 3	0	0	1	1
Ephrin type-A receptor 5	0	0	1	1
Ephrin type-B receptor 4	0	0	1	1
Ephrin type-A receptor 4	0	0	1	1
Adenylate kinase 2, mitochondrial	0	0	1	1
Adenosine kinase	0	0	1	1
Ras-related protein Rab-10	0	0	1	1
Actin-related protein 3	0	0	1	1
Actin-related protein 2	0	0	1	1
GTP-binding nuclear protein Ran	0	0	1	1
Peptidyl-prolyl cis-trans isomerase FKBP1A	0	2	1	3
Peptidyl-prolyl cis-trans isomerase FKBP1B	0	0	1	1
Casein kinase I isoform gamma-2	0	0	1	1
Cyclin-dependent kinase 6	0	0	1	1
Cyclin-dependent-like kinase 5	0	0	1	1
Cyclin-dependent kinase 16	0	0	1	1
Cyclin-dependent kinase 17	0	0	1	1
ATP-dependent 6-phosphofructokinase, platelet type	0	0	1	1
DNA topoisomerase 2-beta	0	0	1	1
Protein kinase C theta type	0	0	1	1
Activin receptor type-1	0	0	1	1
Macrophage-stimulating protein receptor	0	0	1	1
Focal adhesion kinase 1	0	0	1	1
Protein kinase C zeta type	0	0	1	1
Protein kinase C delta type	0	0	1	1
Tyrosine-protein kinase BTK	0	0	1	1
Cyclin-dependent kinase 18	0	0	1	1
Activated CDC42 kinase 1	0	0	1	1
Epithelial discoidin domain-containing receptor 1	0	0	1	1
Mitogen-activated protein kinase kinase kinase kinase 2	0	0	1	1
Serine/threonine-protein kinase 4	0	0	1	1
5'-AMP-activated protein kinase catalytic subunit alpha-1	0	0	1	1
Dual specificity mitogen-activated protein kinase kinase 5	0	0	1	1
Mitogen-activated protein kinase 7	0	0	1	1
Serine/threonine-protein kinase PAK 2	0	0	1	1
Serine/threonine-protein kinase 3	0	0	1	1
Mitogen-activated protein kinase kinase kinase 1	0	0	1	1
Integrin-linked protein kinase	0	0	1	1
Peptidyl-prolyl cis-trans isomerase FKBP5	0	1	0	1
Rho-associated protein kinase 1	0	0	1	1
Non-receptor tyrosine-protein kinase TNK1	0	0	1	1
Calcium/calmodulin-dependent protein kinase type II subunit gamma	0	0	1	1
Calcium/calmodulin-dependent protein kinase type II subunit delta	0	0	1	1
Activin receptor type-2B	0	0	1	1
Bone morphogenetic protein receptor type-2	0	0	1	1
Protein-tyrosine kinase 6	0	0	1	1
cGMP-dependent protein kinase 1	0	0	1	1
Cyclin-dependent kinase 13	0	0	1	1
Inhibitor of nuclear factor kappa-B kinase subunit epsilon	0	0	1	1
Protein-tyrosine kinase 2-beta	0	0	1	1
Maternal embryonic leucine zipper kinase	0	0	1	1
Structural maintenance of chromosomes protein 1A	0	0	1	1
Chromodomain-helicase-DNA-binding protein 4	0	0	1	1
Peroxisomal acyl-coenzyme A oxidase 1	0	0	1	1
Delta(24)-sterol reductase	0	0	1	1
Dual specificity testis-specific protein kinase 1	0	0	1	1
Myosin light chain kinase, smooth muscle	0	0	1	1
Serine/threonine-protein kinase STK11	0	0	1	1
Serine/threonine-protein kinase N1	0	0	1	1
Serine/threonine-protein kinase N2	0	0	1	1
Calcium/calmodulin-dependent protein kinase type IV	0	0	1	1
Mitogen-activated protein kinase kinase kinase 11	0	0	1	1
Discoidin domain-containing receptor 2	0	0	1	1
AP2-associated protein kinase 1	0	0	1	1
Myosin light chain kinase 3	0	0	1	1
Uncharacterized aarF domain-containing protein kinase 5	0	0	1	1
Programmed cell death protein 4	0	0	1	1
Putative heat shock protein HSP 90-beta 2	0	0	1	1
Serine/threonine-protein kinase MRCK alpha	0	0	1	1
Serine/threonine-protein kinase MRCK gamma	0	0	1	1
Acyl-CoA dehydrogenase family member 10	0	0	1	1
Serine/threonine-protein kinase N3	0	0	1	1
Serine/threonine-protein kinase ULK3	0	0	1	1
Uncharacterized protein FLJ45252	0	0	1	1
Acyl-CoA dehydrogenase family member 11	0	0	1	1
Serine/threonine-protein kinase/endoribonuclease IRE2	0	0	1	1
Serine/threonine-protein kinase MARK2	0	0	1	1
ATP-dependent RNA helicase DHX30	0	0	1	1
Serine/threonine-protein kinase TAO1	0	0	1	1
STE20-related kinase adapter protein alpha	0	0	1	1
Myosin-14	0	0	1	1
AarF domain-containing protein kinase 1	0	0	1	1
Mitogen-activated protein kinase kinase kinase kinase 3	0	0	1	1
MAP kinase-activated protein kinase 5	0	0	1	1
Regulatory-associated protein of mTOR	0	1	0	1
Misshapen-like kinase 1	0	0	1	1
Atypical kinase COQ8A, mitochondrial	0	0	1	1
Phosphatidylinositol 5-phosphate 4-kinase type-2 gamma	0	0	1	1
Mitogen-activated protein kinase 15	0	0	1	1
Serine/threonine-protein kinase Nek9	0	0	1	1
ATP-dependent RNA helicase DDX1	0	0	1	1
Mitogen-activated protein kinase kinase kinase kinase 1	0	0	1	1
Aurora kinase B	0	0	1	1
MAP/microtubule affinity-regulating kinase 4	0	0	1	1
Calcium/calmodulin-dependent protein kinase type 1G	0	0	1	1
Serine/threonine-protein kinase Nek1	0	0	1	1
PAS domain-containing serine/threonine-protein kinase	0	0	1	1
Calcium/calmodulin-dependent protein kinase kinase 2	0	0	1	1
EKC/KEOPS complex subunit TP53RK	0	0	1	1
Dual specificity testis-specific protein kinase 2	0	0	1	1
Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase	0	0	1	1
Mitogen-activated protein kinase kinase kinase 5	0	0	1	1
Mitogen-activated protein kinase kinase kinase 3	0	0	1	1
Eukaryotic translation initiation factor 2-alpha kinase 1	0	0	1	1
Target of rapamycin complex subunit LST8	0	1	0	1
Nucleolar GTP-binding protein 1	0	0	1	1
Serine/threonine-protein kinase D2	0	0	1	1
RNA cytidine acetyltransferase	0	0	1	1
Serine/threonine-protein kinase SIK2	0	0	1	1
STE20-like serine/threonine-protein kinase	0	0	1	1
Serine/threonine-protein kinase TAO3	0	0	1	1
dCTP pyrophosphatase 1	0	0	1	1
Dual specificity protein kinase CLK4	0	0	1	1
Casein kinase I isoform gamma-1	0	0	1	1
Serine/threonine-protein kinase mTOR	0	1	0	1
Phenylalanine--tRNA ligase beta subunit	0	0	1	1
Isoleucine--tRNA ligase, mitochondrial	0	0	1	1
BMP-2-inducible protein kinase	0	0	1	1
Obg-like ATPase 1	0	0	1	1
Midasin	0	0	1	1
Interleukin-1 receptor-associated kinase 4	0	0	1	1
Mitogen-activated protein kinase kinase kinase 20	0	0	1	1
Cyclin-dependent kinase 12	0	0	1	1
Serine/threonine-protein kinase 26	0	0	1	1
Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial	0	0	1	1
Serine/threonine-protein kinase NLK	0	0	1	1
5'-AMP-activated protein kinase subunit gamma-2	0	0	1	1
Serine/threonine-protein kinase TBK1	0	0	1	1
Septin-9	0	0	1	1
Ribosomal protein S6 kinase alpha-6	0	0	1	1
TRAF2 and NCK-interacting protein kinase	0	0	1	1
Serine/threonine-protein kinase TAO2	0	0	1	1
Serine/threonine-protein kinase ICK	0	0	1	1
RAC-gamma serine/threonine-protein kinase	0	0	1	1
Serine/threonine-protein kinase SIK3	0	0	1	1
Mitogen-activated protein kinase kinase kinase 2	0	0	1	1
Thyroid hormone receptor-associated protein 3	0	0	1	1
Dual specificity tyrosine-phosphorylation-regulated kinase 1B	0	0	1	1
Mitogen-activated protein kinase kinase kinase kinase 5	0	0	1	1
Receptor-interacting serine/threonine-protein kinase 3	0	0	1	1
Serine/threonine-protein kinase MRCK beta	0	0	1	1
Interleukin-1 receptor-associated kinase 3	0	0	1	1
Serine/threonine-protein kinase 24	0	0	1	1
Casein kinase I isoform gamma-3	0	0	1	1
Mitogen-activated protein kinase kinase kinase 4	0	0	1	1
Chain A, Ribosomal protein S6 kinase alpha-1	0	1	0	1
Chain X, Tyrosine-protein kinase Lyn	0	1	0	1
Chain A, Dual specificity protein kinase TTK	0	0	1	1
Chain A, Dual specificity protein kinase TTK	0	0	1	1
Cytochrome P450 14alpha-demethylase	0	0	1	1
Sterol 14-alpha demethylase	0	1	0	1
Carnitine O-palmitoyltransferase 1, muscle isoform	0	1	0	1
Synaptic vesicular amine transporter	0	2	1	3
Synaptic vesicular amine transporter	0	1	0	1
Thymidine phosphorylase	0	1	0	1
Chain A, Carbonic anhydrase 1	0	1	0	1
Carbonic anhydrase	0	0	0	1
Carbonic anhydrase	0	1	0	1
Carbonic anhydrase	0	1	0	1
Carbonic anhydrase	0	1	0	1
Carbonic anhydrase	0	1	0	1
Carbonic anhydrase	0	1	0	1
Prolyl endopeptidase	0	1	0	1
Carbonic anhydrase-related protein 11	0	0	0	1
Sodium channel protein type 2 subunit alpha	0	1	0	1
Cytochrome P450 2C8	0	1	0	1
Arachidonate 5-lipoxygenase-activating protein	0	1	0	1
Carbonic anhydrase 5A, mitochondrial	0	1	0	1
Carbonic anhydrase 2	0	1	0	1
Carbonic anhydrase	0	1	0	1
Beta-carbonic anhydrase 1	0	1	0	1
Carbonic anhydrase 2	0	1	0	1
Carbonic anhydrase, alpha family	0	1	0	1
Carbonic anhydrase	0	1	0	1
Delta carbonic anhydrase	0	1	0	1
Chain A, CHORISMATE MUTASE	0	1	0	1
Chain A, TYROSYL-tRNA SYNTHETASE	0	0	1	1
Tubulin--tyrosine ligase	0	1	0	1
Taste receptor type 2 member 14	0	0	0	1
Urease subunit alpha	0	1	0	1
Urease subunit beta	0	1	0	1
Olfactory receptor 51E2	0	0	1	1
Carbonic anhydrase	0	1	0	1
Chain A, Arginase 1	0	1	0	1
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]

Autosomal Dominant Hereditary Spastic Paraplegia

Synonyms(36)

Research Excerpts

Overview

Treatment

Research

Studies (199)

Protein Targets (1,403)

Autosomal Dominant Hereditary Spastic Paraplegia

Synonyms(36)

Research Excerpts

Overview

Treatment

Research

Studies (199)

Drugs Studied (144)

Protein Targets (1,403)