Page last updated: 2024-09-27

Autoimmune Demyelinating Diseases, Central Nervous System

Conditions characterized by loss or dysfunction of myelin (see MYELIN SHEATH) in the brain, spinal cord, or optic nerves secondary to autoimmune mediated processes. This may take the form of a humoral or cellular immune response directed toward myelin or OLIGODENDROGLIA associated autoantigens.

Synonyms(18)

Synonym
Demyelinating Autoimmune Diseases, CNS
Spinal Cord Demyelinating Autoimmune Diseases
Brain Autoimmune Demyelinating Diseases
CNS Autoimmune Demyelinating Disorders
Demyelinating Autoimmune Diseases, Brain
Demyelinating Autoimmune Diseases, Central Nervous System
Autoimmune Demyelinating Diseases, Spinal Cord
Demyelinating Autoimmune Diseases, Cerebral
Demyelinating Autoimmune Diseases, Spinal Cord
Demyelinating Autoimmune Disorders, CNS
Demyelinating Disease, Autoimmune, CNS
CNS Demyelinating Autoimmune Diseases
Cerebral Demyelinating Diseases, Autoimmune
Autoimmune Demyelinating Diseases, CNS
Autoimmune Diseases, Demyelinating, Brain
Autoimmune Demyelinating Diseases, Cerebral
Autoimmune Demyelinating Disorders, CNS
Autoimmune Demyelinating Diseases, Central Nervous System

Research

Studies (79)

TimeframeStudies, This Condition (%)All Conditions %
pre-19900 (0.00)23.3326
1990's0 (0.00)12.5806
2000's37 (46.84)18.1394
2010's34 (43.04)28.8240
2020's8 (10.13)9.53
DrugIndicatedRelationship StrengthStudiesTrials
adenine0low10
choline0low10
nitrous oxide0low10
azathioprine0low10
berberine0low10
go 69760low10
ethidium0low10
pentoxifylline0low10
corticosterone0low10
prednisolone0low30
thyroxine0low10
prednisone0low30
aspartic acid0low10
carbostyril0low10
valine0low10
arginine0low10
methylprednisolone0low80
cuprizone0low50
citrulline0low10
cladribine0low10
vidarabine0low10
thallium chloride0low10
glutamic acid0low10
propiconazole0low10
fomesafen0low10
n-acetylaspartic acid0low10
fluorodeoxyglucose f180low10
fingolimod hydrochloride0low30
angiotensin ii0low10
lenalidomide0low10
mycophenolic acid0low30
lisofylline0low10
fludarabine0low10
tamoxifen0low10
krn 70000low10
myelin basic protein0low110
ex 5270low10
sphingosine0low10
vitamin k semiquinone radical0low10
lysophosphatidylcholines0low110
aluminum0low10
thallium0low10
pregabalin0low10
i(3)so3-galactosylceramide0low20
gadolinium dtpa0low10
pci 327650low10
glycolipids0low20
piperidines0low10
interleukin-80low10
minocycline0low10
laquinimod0low10
warfarin0low10
transforming growth factor beta0low20
vitamin b 120low10
myelin oligodendrocyte glycoprotein (35-55)0low60
exudates0low10
acyclovir0low40
neopterin0low10
valacyclovir0low10
eye0low10
gq1b ganglioside0low10

Protein Targets (908)

ProteinPotency MeasurementsInhibition MeasurementsActivation MeasurementsDrugs
Chain E, Purine nucleoside phosphorylase0101
Chain A, HADH2 protein5005
Chain B, HADH2 protein5005
Chain A, ATP-DEPENDENT DNA HELICASE Q12002
Chain A, Ferritin light chain8008
Thymidine kinase 0101
thioredoxin reductase100010
phosphopantetheinyl transferase8008
GLS protein4004
TDP1 protein190019
Smad35005
thyroid stimulating hormone receptor4004
EWS/FLI fusion protein150015
arylsulfatase A5005
euchromatic histone-lysine N-methyltransferase 2140014
activating transcription factor 65005
Histone H2A.x6006
Bloom syndrome protein isoform 15005
hemoglobin subunit beta2002
atrial natriuretic peptide receptor 1 precursor1001
ubiquitin carboxyl-terminal hydrolase 2 isoform a2002
lamin isoform A-delta10100010
Solute carrier family 22 member 1 0204
ATP-binding cassette sub-family C member 30909
Multidrug resistance-associated protein 40909
Solute carrier family 22 member 60001
Bile salt export pump0202
Bile salt export pump012012
Purine nucleoside phosphorylase0101
Thymidine kinase, cytosolic0002
POU domain, class 2, transcription factor 20001
Cytochrome P450 2C9 0506
Cytochrome P450 2J20303
Disintegrin and metalloproteinase domain-containing protein 172002
Purine nucleoside phosphorylase0011
Solute carrier family 22 member 60001
Thymidine kinase 0101
Solute carrier family 22 member 80002
Canalicular multispecific organic anion transporter 10909
Thymidine kinase0101
Chain A, MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASE7007
Chain A, MTA/SAH nucleosidase0101
Chain A, Ribosome-inactivating protein alpha-trichosanthin0011
Chain A, Ricin A chain0011
Chain A, Ribosome-inactivating protein 30011
Chain A, Phenylethanolamine N-methyltransferase0011
Chain A, Phenylethanolamine N-methyltransferase0011
Chain A, Phenylethanolamine N-methyltransferase0011
Chain A, Phenylethanolamine N-methyltransferase0011
Chain A, Phenylethanolamine N-methyltransferase0011
Chain A, Phenylethanolamine N-methyltransferase0011
Chain A, Phenylethanolamine N-methyltransferase0011
Chain A, Phenylethanolamine N-methyltransferase0011
Chain A, Phenylethanolamine N-methyltransferase0011
Chain A, Phenylethanolamine N-methyltransferase0011
Chain A, Phenylethanolamine N-methyltransferase0011
Chain A, Phenylethanolamine N-methyltransferase0011
Chain A, Phenylethanolamine N-methyltransferase0011
RAR-related orphan receptor gamma9009
AR protein120012
nuclear receptor subfamily 1, group I, member 39009
cytochrome P450 family 3 subfamily A polypeptide 44004
glucocorticoid receptor [Homo sapiens]100010
estrogen-related nuclear receptor alpha130013
pregnane X nuclear receptor120012
estrogen nuclear receptor alpha170017
cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a110011
nuclear factor erythroid 2-related factor 2 isoform 29009
heat shock protein beta-14004
importin subunit beta-1 isoform 11001
snurportin-11001
tumor susceptibility gene 101 protein1001
GTP-binding nuclear protein Ran isoform 11001
Voltage-dependent calcium channel gamma-2 subunit6006
Cyclin-dependent kinase 10112
Heat shock protein HSP 90-beta0101
Glutamate receptor 263110
Xanthine dehydrogenase/oxidase0101
TAR DNA-binding protein 433003
Protein mono-ADP-ribosyltransferase PARP150202
Leucine-rich repeat serine/threonine-protein kinase 20202
ATPase family AAA domain-containing protein 58008
Ataxin-28008
glucocerebrosidase3003
DNA polymerase kappa isoform 15005
histone acetyltransferase KAT2A isoform 16006
Atrial natriuretic peptide receptor 30101
Type-1A angiotensin II receptor 0213
Type-1 angiotensin II receptor0011
Type-1B angiotensin II receptor0202
Type-1 angiotensin II receptor0224
Type-2 angiotensin II receptor0202
Type-2 angiotensin II receptor0202
Chain E, LYSINE, ARGININE, ORNITHINE-BINDING PROTEIN0011
Chain E, LYSINE, ARGININE, ORNITHINE-BINDING PROTEIN0011
Chain E, LYSINE, ARGININE, ORNITHINE-BINDING PROTEIN0011
NFKB1 protein, partial3003
alpha-galactosidase2002
cytochrome P450 2C19 precursor2002
chromobox protein homolog 16006
flap endonuclease 12002
DNA polymerase iota isoform a (long)7007
muscarinic acetylcholine receptor M14004
lethal factor (plasmid)4004
Cytochrome P450 3A40305
Nitric oxide synthase, endothelial0002
Nitric oxide synthase, brain0102
Nitric oxide synthase, brain 0102
Nitric oxide synthase, inducible0001
Nitric oxide synthase, inducible0013
Cationic amino acid transporter 30101
ATP-dependent phosphofructokinase3003
Chain A, TYROSYL-DNA PHOSPHODIESTERASE3003
aldehyde dehydrogenase 1 family, member A16006
Metabotropic glutamate receptor 60124
Excitatory amino acid transporter 40202
Glutamate transporter homolog0011
Carbonic anhydrase 10103
Carbonic anhydrase 20103
N(4)-(beta-N-acetylglucosaminyl)-L-asparaginase0101
5-hydroxytryptamine receptor 1D0001
Glutamate receptor ionotropic, NMDA 1 0314
Excitatory amino acid transporter 10304
Excitatory amino acid transporter 20304
Excitatory amino acid transporter 30304
Glutamate receptor ionotropic, NMDA 2A 0314
Glutamate receptor ionotropic, NMDA 2B0314
Glutamate receptor ionotropic, NMDA 2C0314
Metabotropic glutamate receptor 10124
Metabotropic glutamate receptor 20124
Carbonic anhydrase-like protein, putative0002
Glutamate receptor ionotropic, NMDA 2D0314
Glutamate receptor ionotropic, NMDA 3B0314
Carbonic anhydrase 40001
Glutamate receptor ionotropic, NMDA 3A0314
interleukin 81001
acetylcholinesterase4004
SMAD family member 24004
ATAD5 protein, partial3003
Fumarate hydratase7007
SMAD family member 34004
GLI family zinc finger 39009
Microtubule-associated protein tau5005
thioredoxin glutathione reductase4004
retinoic acid nuclear receptor alpha variant 18008
retinoid X nuclear receptor alpha7007
farnesoid X nuclear receptor6006
G5005
polyprotein7007
P531001
peroxisome proliferator-activated receptor delta6006
peroxisome proliferator activated receptor gamma7007
IDH17007
aryl hydrocarbon receptor5005
thyroid stimulating hormone receptor3003
v-jun sarcoma virus 17 oncogene homolog (avian)5005
peripheral myelin protein 22 isoform 12002
cellular tumor antigen p53 isoform a3003
thyroid hormone receptor beta isoform 2100010
nuclear factor erythroid 2-related factor 2 isoform 1100010
geminin110011
peripheral myelin protein 224004
survival motor neuron protein isoform d7007
cytochrome P450 3A4 isoform 15005
M-phase phosphoprotein 82002
muscleblind-like protein 1 isoform 13003
Gamma-aminobutyric acid receptor subunit pi5005
Interferon beta110011
HLA class I histocompatibility antigen, B alpha chain 5005
Cellular tumor antigen p53110011
Gamma-aminobutyric acid receptor subunit beta-15005
Gamma-aminobutyric acid receptor subunit delta5005
Gamma-aminobutyric acid receptor subunit gamma-25005
Gamma-aminobutyric acid receptor subunit alpha-55005
Gamma-aminobutyric acid receptor subunit alpha-35005
Gamma-aminobutyric acid receptor subunit gamma-15005
Gamma-aminobutyric acid receptor subunit alpha-25005
Gamma-aminobutyric acid receptor subunit alpha-45005
Gamma-aminobutyric acid receptor subunit gamma-35005
Gamma-aminobutyric acid receptor subunit alpha-65005
Nuclear receptor ROR-gamma3003
Gamma-aminobutyric acid receptor subunit alpha-15005
Gamma-aminobutyric acid receptor subunit beta-35005
Gamma-aminobutyric acid receptor subunit beta-25005
GABA theta subunit5005
Inositol hexakisphosphate kinase 15005
Gamma-aminobutyric acid receptor subunit epsilon5005
Protein-arginine deiminase type-40303
cytochrome P450 2C9, partial5005
Chain A, Putative fructose-1,6-bisphosphate aldolase4004
PPM1D protein6006
hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)5005
cytochrome P450 2D6 isoform 12002
Telomerase reverse transcriptase0101
Acetylcholinesterase0101
Lysine-specific histone demethylase 1A0101
Neuraminidase0101
Neuraminidase0101
Cholinesterase0202
Tyrosine-protein phosphatase non-receptor type 10101
Acetylcholinesterase0303
Aldo-keto reductase family 1 member C30101
Prolyl endopeptidase0101
Aldo-keto reductase family 1 member C2 0101
Cholinesterase0101
Inositol monophosphatase 13003
Potassium voltage-gated channel subfamily H member 20505
Cytochrome P450 1B10202
Chain A, serum paraoxonase0101
nuclear receptor ROR-gamma isoform 16006
Carbonic anhydrase 120101
Carbonic anhydrase 30101
Neutrophil cytosol factor 10101
Carbonic anhydrase 40101
Carbonic anhydrase 60101
Carbonic anhydrase 5A, mitochondrial0101
Carbonic anhydrase 70101
Carbonic anhydrase 90101
Carbonic anhydrase 130101
Poly [ADP-ribose] polymerase tankyrase-20101
Carbonic anhydrase 140101
Carbonic anhydrase 5B, mitochondrial0101
Chain A, Acetylcholinesterase0011
Chain A, Acetylcholinesterase0011
Chain A, Acetylcholinesterase0011
Chain A, Acetylcholinesterase0011
Chain A, Acetylcholinesterase0011
Chain A, Acetylcholinesterase0011
Chain A, Acetylcholinesterase0011
Chain A, Putative Glycine Betaine-binding Abc Transporter Protein0011
Chain A, PUTATIVE GLYCINE BETAINE-BINDING ABC TRANSPORTER PROTEIN0011
Chain A, Glycine betaine/carnitine/choline-binding protein0011
Chain A, Glycine betaine/carnitine/choline-binding protein0011
Chain A, Glycine betaine/carnitine/choline-binding protein0011
Chain A, Glycine betaine/carnitine/choline-binding protein0011
Chain A, Choline-binding protein0011
Solute carrier family 22 member 10102
Solute carrier family 22 member 20102
Solute carrier family 22 member 20101
Neuronal acetylcholine receptor subunit alpha-30101
Neuronal acetylcholine receptor subunit alpha-40101
Neuronal acetylcholine receptor subunit alpha-20101
Neuronal acetylcholine receptor subunit beta-20101
Neuronal acetylcholine receptor subunit beta-30101
Neuronal acetylcholine receptor subunit beta-40101
Neuronal acetylcholine receptor subunit alpha-50101
Sodium- and chloride-dependent creatine transporter 10101
Choline O-acetyltransferase 0001
Neuronal acetylcholine receptor subunit alpha-60101
Neuronal acetylcholine receptor subunit alpha-90101
Neuronal acetylcholine receptor subunit alpha-70101
Solute carrier family 22 member 10304
High affinity choline transporter 10101
Neuronal acetylcholine receptor subunit alpha-100101
Solute carrier family 22 member 20304
N(G),N(G)-dimethylarginine dimethylaminohydrolase 10101
General amino-acid permease GAP10001
Chain A, BCL-2-RELATED PROTEIN A10011
glp-1 receptor, partial4004
67.9K protein8008
huntingtin isoform 21001
tyrosine-protein kinase Yes3003
urokinase-type plasminogen activator precursor4004
plasminogen precursor4004
urokinase plasminogen activator surface receptor precursor4004
relaxin receptor 1 isoform 12002
bcl-2-like protein 11 isoform 10011
cGMP-dependent 3',5'-cyclic phosphodiesterase0202
Integrin beta-32013
Integrin alpha-IIb2013
Deoxycytidine kinase0012
Adenosine receptor A30202
Rap guanine nucleotide exchange factor 42002
pregnane X receptor3003
GALC protein1001
Thrombopoietin1001
progesterone receptor9009
nonstructural protein 13003
vitamin D (1,25- dihydroxyvitamin D3) receptor5005
nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105), isoform CRA_a3003
thyroid hormone receptor beta isoform a6006
mitogen-activated protein kinase 12002
serine/threonine-protein kinase mTOR isoform 12002
Solute carrier family 22 member 30202
Solute carrier family 22 member 30101
Sex hormone-binding globulin0011
Corticosteroid-binding globulin0202
Mineralocorticoid receptor 0224
Androgen receptor0606
C-8 sterol isomerase0202
Solute carrier organic anion transporter family member 1A10101
3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase0314
Sigma non-opioid intracellular receptor 10303
vitamin D3 receptor isoform VDRA6006
Reverse transcriptase/RNaseH 0101
Histone deacetylase 30101
ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 10101
Histone deacetylase 40101
Histone deacetylase 10101
NAD-dependent protein deacetylase sirtuin-20202
Histone deacetylase 70101
Histone deacetylase 20101
Polyamine deacetylase HDAC100101
Histone deacetylase 11 0101
NAD-dependent protein deacetylase sirtuin-10204
Histone deacetylase 80101
NAD-dependent protein deacetylase sirtuin-3, mitochondrial0101
NAD-dependent protein deacylase sirtuin-5, mitochondrial0101
Histone deacetylase 60101
Histone deacetylase 90101
Histone deacetylase 50101
Sphingosine 1-phosphate receptor 10011
RCG53912, isoform CRA_a 0001
Sphingosine kinase 1 0001
Sphingosine kinase 20102
Sphingosine kinase 10102
Chain A, Beta-lactamase6006
corticotropin-releasing hormone receptor 20112
corticotropin releasing factor-binding protein0112
glycogen synthase kinase-3 beta isoform 10022
5'-nucleotidase0101
Adenosine deaminase 0002
Luciferase3003
hypoxia-inducible factor 1 alpha subunit4004
Chain A, GLUTAMATE RECEPTOR SUBUNIT 20101
Chain A, Glutamate Receptor Subunit 20101
Chain B, Glutamate Receptor Subunit 20101
Chain A, Slr1257 protein0011
Chain A, Glucosamine--fructose-6-phosphate aminotransferase [isomerizing]0101
regulator of G-protein signaling 44004
beta-2 adrenergic receptor1001
peptidyl-prolyl cis-trans isomerase NIMA-interacting 13003
Metabotropic glutamate receptor 80202
Glutamate receptor ionotropic, NMDA 2D0101
Glutamate receptor ionotropic, NMDA 3B0101
Glutathione reductase, mitochondrial0202
Bifunctional aspartokinase/homoserine dehydrogenase 10101
Prothrombin0011
ATP-citrate synthase 0101
Glutamate receptor 10314
Glutamate receptor 30314
Glutamate receptor 40314
Glutamate receptor ionotropic, kainate 10213
Metabotropic glutamate receptor 10112
Metabotropic glutamate receptor 20011
Metabotropic glutamate receptor 30011
Metabotropic glutamate receptor 40112
Metabotropic glutamate receptor 50011
Metabotropic glutamate receptor 60011
Metabotropic glutamate receptor 70011
Glutamate receptor ionotropic, kainate 10112
Metabotropic glutamate receptor 50113
Glutamate receptor ionotropic, kainate 20213
Glutamate receptor 10213
Glutamate receptor 20213
Glutamate receptor 30112
Glutamate receptor ionotropic, kainate 30202
Metabotropic glutamate receptor 80011
Glutamate receptor 40213
Excitatory amino acid transporter 3 0001
Glutamate racemase0001
Metabotropic glutamate receptor 80112
Fatty-acid amide hydrolase 10101
Glutamate receptor ionotropic, kainate 40202
Glutamate carboxypeptidase 20101
Glutamate receptor ionotropic, NMDA 10101
Glutamate receptor ionotropic, NMDA 2A0101
Glutamate receptor ionotropic, kainate 20112
Glutamate receptor ionotropic, kainate 30101
Glutamate receptor ionotropic, NMDA 2B0101
Metabotropic glutamate receptor 70113
Metabotropic glutamate receptor 30113
Metabotropic glutamate receptor 40113
Glutamate receptor ionotropic, NMDA 2C0101
Glutamate receptor ionotropic, kainate 50101
Glutamate receptor ionotropic, kainate 50202
Glutamate racemase0001
Prolyl 4-hydroxylase0101
Glutamate receptor ionotropic, NMDA 3A0101
Alpha-ketoglutarate-dependent dioxygenase FTO0101
Serine/threonine-protein kinase PLK40112
Protein kinase C gamma type0202
Protein kinase C beta type0213
Protein kinase C alpha type0213
Serine/threonine-protein kinase PLK10112
Protein kinase C delta type0213
Serine/threonine-protein kinase D10202
Serine/threonine-protein kinase PLK30101
Serine/threonine-protein kinase PLK20101
Cereblon isoform 40101
Bromodomain-containing protein 40101
Tyrosine-protein kinase ABL10012
Breakpoint cluster region protein0012
DNA-binding protein Ikaros0013
DNA damage-binding protein 10101
Protein cereblon0215
Zinc finger protein Aiolos0011
bromodomain adjacent to zinc finger domain 2B2002
nuclear receptor subfamily 1, group I, member 22002
Nuclear receptor subfamily 1 group I member 20022
Glucocorticoid receptor06213
Glycine receptor subunit alpha-10606
Glycine receptor subunit beta0606
Glycine receptor subunit alpha-20606
Glycine receptor subunit alpha-30606
Nuclear receptor subfamily 1 group I member 20011
Albumin0022
Stromelysin-10101
Matrilysin0101
Multidrug transporter MdfA0101
Matrix metalloproteinase-90101
Chain A, Inosine-5'-Monophosphate Dehydrogenase 20101
Chain A, 2-oxoglutarate Oxygenase2002
estrogen receptor 2 (ER beta)4004
15-hydroxyprostaglandin dehydrogenase [NAD(+)] isoform 11001
UDP-glucuronosyltransferase 1A90001
Inosine-5'-monophosphate dehydrogenase 20213
Inosine-5'-monophosphate dehydrogenase 1 0202
UDP-glucuronosyltransferase 1A1 0102
Sodium-dependent serotonin transporter0101
Peroxisome proliferator-activated receptor gamma0033
Alpha-synuclein2002
Inosine-5'-monophosphate dehydrogenase0102
UDP-glucuronosyltransferase 1A70001
UDP-glucuronosyltransferase 1A100001
UDP-glucuronosyltransferase 1A80001
transcriptional regulator ERG isoform 32002
Solute carrier family 22 member 200101
Solute carrier family 22 member 60101
Bone morphogenetic protein receptor type-1B0011
Cell division cycle 7-related protein kinase0011
ATP-dependent RNA helicase DDX3X0011
Pyridoxal kinase0011
Citron Rho-interacting kinase0011
Serine/threonine-protein kinase Chk10011
Aurora kinase A0011
Cyclin-G-associated kinase0011
Ephrin type-B receptor 60011
Peroxisomal acyl-coenzyme A oxidase 30011
Receptor-interacting serine/threonine-protein kinase 20011
Mitotic checkpoint serine/threonine-protein kinase BUB10011
Testosterone 17-beta-dehydrogenase 30101
Dynamin-like 120 kDa protein, mitochondrial0011
Putative nucleoside diphosphate kinase0011
Tyrosine-protein kinase JAK20202
Rho-associated protein kinase 20011
Serine/threonine-protein kinase ULK10011
Serine/threonine-protein kinase/endoribonuclease IRE10011
Ribosomal protein S6 kinase alpha-50011
U5 small nuclear ribonucleoprotein 200 kDa helicase0011
Ribosomal protein S6 kinase alpha-40011
Serine/threonine-protein kinase 160011
Serine/threonine-protein kinase 100011
Serine/threonine-protein kinase D30112
Structural maintenance of chromosomes protein 20011
Mitogen-activated protein kinase kinase kinase 60011
Mitogen-activated protein kinase kinase kinase kinase 40011
Serine/threonine-protein kinase LATS10011
Serine/threonine-protein kinase PAK 40011
Epidermal growth factor receptor0325
Receptor tyrosine-protein kinase erbB-20213
High affinity nerve growth factor receptor0011
Guanine nucleotide-binding protein G(i) subunit alpha-20011
ADP/ATP translocase 20011
Cytochrome P450 1A20101
Insulin receptor0011
Tyrosine-protein kinase Lck0213
Tyrosine-protein kinase Fyn0213
Glycogen phosphorylase, liver form0011
Tyrosine-protein kinase Fes/Fps0011
Macrophage colony-stimulating factor 1 receptor0101
Adenine phosphoribosyltransferase0011
Tyrosine-protein kinase Yes0112
Tyrosine-protein kinase Lyn0112
Proto-oncogene tyrosine-protein kinase receptor Ret0112
Insulin-like growth factor 1 receptor0011
Signal recognition particle receptor subunit alpha0011
Cytochrome c1, heme protein, mitochondrial0011
Hepatocyte growth factor receptor0011
Tyrosine-protein kinase HCK0112
Platelet-derived growth factor receptor beta0112
Tyrosine-protein kinase Fgr0101
Serine/threonine-protein kinase A-Raf0011
Cytochrome P450 2C80102
Cytochrome P450 2D60101
Glycogen phosphorylase, brain form0011
Serine/threonine-protein kinase pim-10011
Fibroblast growth factor receptor 10011
DNA topoisomerase 2-alpha0011
Cyclin-dependent kinase 40011
ADP/ATP translocase 30011
Proto-oncogene tyrosine-protein kinase Src0112
cAMP-dependent protein kinase type II-alpha regulatory subunit0011
Serine/threonine-protein kinase B-raf0011
Phosphorylase b kinase gamma catalytic chain, liver/testis isoform0011
Ribosyldihydronicotinamide dehydrogenase [quinone]0011
Tyrosine-protein kinase Fer0011
cAMP-dependent protein kinase catalytic subunit alpha0011
General transcription and DNA repair factor IIH helicase subunit XPD0011
Casein kinase II subunit alpha'0011
Ras-related protein Rab-6A0011
Cytochrome P450 2B60203
Ephrin type-A receptor 10011
Receptor tyrosine-protein kinase erbB-30101
Multifunctional protein ADE20011
Nucleoside diphosphate kinase B0011
cAMP-dependent protein kinase catalytic subunit gamma0011
cAMP-dependent protein kinase catalytic subunit beta0011
Ferrochelatase, mitochondrial0011
Ribosomal protein S6 kinase beta-10011
Tyrosine-protein kinase JAK10213
G1/S-specific cyclin-E10101
Cyclin-dependent kinase 20112
Beta-adrenergic receptor kinase 10011
Probable ATP-dependent RNA helicase DDX60011
Mitogen-activated protein kinase 3 0011
MAP/microtubule affinity-regulating kinase 30011
Mitogen-activated protein kinase 10011
Ephrin type-A receptor 20112
Ephrin type-B receptor 20011
Non-receptor tyrosine-protein kinase TYK20011
Phosphatidylethanolamine-binding protein 10011
Wee1-like protein kinase0011
Heme oxygenase 20011
S-adenosylmethionine synthase isoform type-20011
DnaJ homolog subfamily A member 10011
RAC-alpha serine/threonine-protein kinase0011
RAC-beta serine/threonine-protein kinase0011
Cytochrome P450 2C190102
Dual specificity protein kinase TTK0011
DNA replication licensing factor MCM40011
Myosin-100011
Dual specificity mitogen-activated protein kinase kinase 20112
Receptor-type tyrosine-protein kinase FLT30213
Bone morphogenetic protein receptor type-1A0011
Activin receptor type-1B0011
TGF-beta receptor type-10011
TGF-beta receptor type-20011
Tyrosine-protein kinase CSK0112
Glycine--tRNA ligase0011
Protein kinase C iota type0112
Exosome RNA helicase MTR40011
Tyrosine-protein kinase Tec0112
Tyrosine-protein kinase TXK0112
Tyrosine-protein kinase ABL20011
Tyrosine-protein kinase FRK0112
G protein-coupled receptor kinase 60011
Tyrosine-protein kinase SYK0112
26S proteasome regulatory subunit 6B0011
Mitogen-activated protein kinase 80011
Mitogen-activated protein kinase 90011
Dual specificity mitogen-activated protein kinase kinase 30011
Phosphatidylinositol 5-phosphate 4-kinase type-2 alpha0011
Casein kinase I isoform delta0011
MAP kinase-activated protein kinase 20011
Elongation factor Tu, mitochondrial0011
Choline-phosphate cytidylyltransferase A0011
Casein kinase I isoform epsilon0011
Very long-chain specific acyl-CoA dehydrogenase, mitochondrial0011
Dual specificity protein kinase CLK10011
Dual specificity protein kinase CLK20011
Glycogen synthase kinase-3 alpha0011
Glycogen synthase kinase-3 beta0011
Cyclin-dependent kinase 70011
Cyclin-dependent kinase 90011
Ras-related protein Rab-27A0011
Tyrosine-protein kinase Blk0112
Interleukin-1 receptor-associated kinase 10011
Ribosomal protein S6 kinase alpha-30011
Cytoplasmic tyrosine-protein kinase BMX0213
cAMP-dependent protein kinase catalytic subunit PRKX0011
Serine/threonine-protein kinase Nek20011
Serine/threonine-protein kinase Nek30011
Tyrosine-protein kinase JAK30112
Dual specificity mitogen-activated protein kinase kinase 60011
LIM domain kinase 10011
LIM domain kinase 20011
Mitogen-activated protein kinase 100011
Tyrosine--tRNA ligase, cytoplasmic0011
5'-AMP-activated protein kinase subunit gamma-10011
Ephrin type-B receptor 30011
Ephrin type-A receptor 50011
Ephrin type-B receptor 40011
Ephrin type-A receptor 40011
Adenylate kinase 2, mitochondrial0011
Adenosine kinase0011
Ras-related protein Rab-100011
Actin-related protein 30011
Actin-related protein 20011
GTP-binding nuclear protein Ran0011
Casein kinase I isoform gamma-20011
Cyclin-dependent kinase 30011
Cyclin-dependent kinase 60011
Cyclin-dependent-like kinase 5 0011
Cyclin-dependent kinase 160011
Cyclin-dependent kinase 170011
ATP-dependent 6-phosphofructokinase, platelet type0011
Dual specificity mitogen-activated protein kinase kinase 10011
DNA topoisomerase 2-beta0011
Protein kinase C theta type0112
Activin receptor type-10011
Macrophage-stimulating protein receptor0011
Focal adhesion kinase 10011
Tyrosine-protein kinase BTK0224
Activated CDC42 kinase 10011
Epithelial discoidin domain-containing receptor 10011
Tyrosine-protein kinase ITK/TSK0112
Mitogen-activated protein kinase kinase kinase kinase 20011
Tyrosine-protein kinase Mer0011
Serine/threonine-protein kinase 40011
5'-AMP-activated protein kinase catalytic subunit alpha-10011
Dual specificity mitogen-activated protein kinase kinase 50011
Mitogen-activated protein kinase 70011
Serine/threonine-protein kinase PAK 20011
Serine/threonine-protein kinase 30011
Mitogen-activated protein kinase kinase kinase 10011
Integrin-linked protein kinase0011
Rho-associated protein kinase 10011
Non-receptor tyrosine-protein kinase TNK10011
Calcium/calmodulin-dependent protein kinase type II subunit gamma0011
Calcium/calmodulin-dependent protein kinase type II subunit delta0011
Dual specificity tyrosine-phosphorylation-regulated kinase 1A0011
Activin receptor type-2B0011
Bone morphogenetic protein receptor type-20011
Protein-tyrosine kinase 60112
cGMP-dependent protein kinase 1 0011
Cyclin-dependent kinase 130011
Inhibitor of nuclear factor kappa-B kinase subunit epsilon0011
Protein-tyrosine kinase 2-beta0011
Maternal embryonic leucine zipper kinase0011
Structural maintenance of chromosomes protein 1A0011
Chromodomain-helicase-DNA-binding protein 40011
Serine/threonine-protein kinase 380011
Receptor tyrosine-protein kinase erbB-40112
Ephrin type-A receptor 70011
Delta(24)-sterol reductase0011
Ribosomal protein S6 kinase alpha-10112
Myosin light chain kinase, smooth muscle0011
Mitogen-activated protein kinase 110011
Serine/threonine-protein kinase STK110011
Serine/threonine-protein kinase N10011
Serine/threonine-protein kinase N20011
Mitogen-activated protein kinase 140011
Calcium/calmodulin-dependent protein kinase type IV0011
Mitogen-activated protein kinase kinase kinase 110011
MAP kinase-activated protein kinase 30011
Discoidin domain-containing receptor 20011
AP2-associated protein kinase 10011
Myosin light chain kinase 30011
Putative heat shock protein HSP 90-beta 20011
Rab-like protein 30011
Sigma intracellular receptor 20101
Serine/threonine-protein kinase MRCK alpha0011
Serine/threonine-protein kinase MRCK gamma0011
Acyl-CoA dehydrogenase family member 100011
Serine/threonine-protein kinase ULK30011
Uncharacterized protein FLJ452520011
Acyl-CoA dehydrogenase family member 110011
Serine/threonine-protein kinase/endoribonuclease IRE20011
Serine/threonine-protein kinase MARK20011
ATP-dependent RNA helicase DHX300011
Serine/threonine-protein kinase TAO10011
STE20-related kinase adapter protein alpha0011
Myosin-140011
AarF domain-containing protein kinase 10011
ATP-dependent RNA helicase DDX420011
Mitogen-activated protein kinase kinase kinase kinase 30011
MAP kinase-activated protein kinase 50011
Misshapen-like kinase 10011
Atypical kinase COQ8A, mitochondrial0011
Phosphatidylinositol 5-phosphate 4-kinase type-2 gamma0011
Mitogen-activated protein kinase 150011
Serine/threonine-protein kinase Nek90011
Serine/threonine-protein kinase Nek70011
ATP-dependent RNA helicase DDX10011
Nuclear receptor subfamily 4 group A member 30101
Mitogen-activated protein kinase kinase kinase kinase 10011
Aurora kinase B0011
MAP/microtubule affinity-regulating kinase 40011
Calcium/calmodulin-dependent protein kinase type 1G0011
Serine/threonine-protein kinase Nek10011
PAS domain-containing serine/threonine-protein kinase0011
Calcium/calmodulin-dependent protein kinase kinase 20011
EKC/KEOPS complex subunit TP53RK0011
Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase0011
Mitogen-activated protein kinase kinase kinase 50011
Mitogen-activated protein kinase kinase kinase 30011
Eukaryotic translation initiation factor 2-alpha kinase 10011
Peroxiredoxin-like 2A0101
Nucleolar GTP-binding protein 10011
Serine/threonine-protein kinase D20011
NUAK family SNF1-like kinase 20011
RNA cytidine acetyltransferase0011
Serine/threonine-protein kinase SIK20011
STE20-like serine/threonine-protein kinase 0011
Serine/threonine-protein kinase TAO30011
dCTP pyrophosphatase 10011
Dual specificity protein kinase CLK40011
Platelet glycoprotein VI0101
Casein kinase I isoform gamma-10011
Serine/threonine-protein kinase PAK 60011
Phenylalanine--tRNA ligase beta subunit0011
BMP-2-inducible protein kinase0011
Obg-like ATPase 10011
Midasin0011
Interleukin-1 receptor-associated kinase 40011
Mitogen-activated protein kinase kinase kinase 200011
Cyclin-dependent kinase 120011
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 130011
Serine/threonine-protein kinase 260011
Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial0011
Serine/threonine-protein kinase NLK0011
5'-AMP-activated protein kinase subunit gamma-20011
Serine/threonine-protein kinase TBK10011
Septin-90011
Ribosomal protein S6 kinase alpha-60011
TRAF2 and NCK-interacting protein kinase0011
Serine/threonine-protein kinase TAO20011
Serine/threonine-protein kinase ICK0011
RAC-gamma serine/threonine-protein kinase0011
Serine/threonine-protein kinase SIK30011
Mitogen-activated protein kinase kinase kinase 20011
Thyroid hormone receptor-associated protein 30011
Dual specificity tyrosine-phosphorylation-regulated kinase 1B0011
Mitogen-activated protein kinase kinase kinase kinase 50011
Receptor-interacting serine/threonine-protein kinase 30011
Serine/threonine-protein kinase MRCK beta0011
Interleukin-1 receptor-associated kinase 30011
Serine/threonine-protein kinase 240011
Casein kinase I isoform gamma-30011
Mitogen-activated protein kinase kinase kinase 40011
endonuclease IV2002
dopamine D1 receptor1001
vasopressin V1b receptor1001
High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8A0101
cGMP-specific 3',5'-cyclic phosphodiesterase0101
Tumor necrosis factor0101
cAMP-specific 3',5'-cyclic phosphodiesterase 4A0101
Adenosine receptor A2b0101
Spike glycoprotein1012
cAMP-specific 3',5'-cyclic phosphodiesterase 4B0101
cAMP-specific 3',5'-cyclic phosphodiesterase 4D0101
Chitotriosidase-10213
cGMP-inhibited 3',5'-cyclic phosphodiesterase A0101
Endochitinase B10213
luciferase0001
Fatty acid-binding protein, liver0101
Estrogen receptor0416
Progesterone receptor0304
Glucocorticoid receptor0112
Glucocorticoid receptor0011
Androgen receptor0202
Glutamine synthetase0011
Histamine H1 receptor0022
Prostaglandin G/H synthase 20101
Nociceptin receptor0011
Estrogen receptor beta0415
Sodium-dependent noradrenaline transporter 0404
Voltage-dependent calcium channel subunit alpha-2/delta-10102
Voltage-dependent calcium channel subunit alpha-2/delta-20101
heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)1001
heat shock protein HSP 90-alpha isoform 20001
Polyunsaturated fatty acid lipoxygenase ALOX15B2002
Histamine H2 receptor2002
Guanine nucleotide-binding protein G1001
heat shock protein 90, putative0001
Chain A, Cruzipain1001
acid sphingomyelinase1001
USP1 protein, partial4004
apical membrane antigen 1, AMA13003
potassium voltage-gated channel subfamily H member 2 isoform d1001
C-X-C chemokine receptor type 5 isoform 10101
DNA polymerase beta1001
ubiquitin-conjugating enzyme E2 N0202
C-C chemokine receptor type 60101
apelin receptor0101
DNA polymerase eta isoform 12002
bcl-2-related protein A10101
streptokinase A precursor0022
Endoglycoceramidase II 0001
Protein kinase C alpha type0202
Estrogen receptor0023
Protein kinase C delta type0202
Protein kinase C epsilon type0202
Protein kinase C zeta type0202
cAMP-dependent protein kinase catalytic subunit alpha 0101
Protein kinase C gamma type0202
Protein kinase C beta type0202
Estrogen receptor beta0023
Protein kinase C eta type0202
Protein kinase C theta type0202
Chain A, CES1 protein0101
Chain A, JmjC domain-containing histone demethylation protein 3A1001
DNA polymerase III, partial1001
caspase 7, apoptosis-related cysteine protease1001
caspase-31001
thyrotropin-releasing hormone receptor1001
Caspase-71001
Spike glycoprotein0011
Replicase polyprotein 1ab0011
NPC intracellular cholesterol transporter 1 precursor1001
interferon gamma precursor0001
D(1A) dopamine receptor1001
caspase-31001
ras-related protein Rab-9A1001
Transmembrane protease serine 20011
5-hydroxytryptamine receptor 40202
Lysosomal acid glucosylceramidase0011
Procathepsin L0011
Aldo-keto reductase family 1 member B10202
Muscarinic acetylcholine receptor M20202
Muscarinic acetylcholine receptor M40202
ATP-dependent translocase ABCB10213
Beta-1 adrenergic receptor0202
Muscarinic acetylcholine receptor M50202
Alpha-2A adrenergic receptor0202
Polyunsaturated fatty acid 5-lipoxygenase0101
Replicase polyprotein 1a0011
Replicase polyprotein 1ab0011
Replicase polyprotein 1ab0011
Adenosine receptor A30202
Replicase polyprotein 1ab0011
Muscarinic acetylcholine receptor M10202
Steroid hormone receptor ERR10101
Transcriptional activator protein LuxR0101
Angiotensin-converting enzyme0202
Beta-3 adrenergic receptor0202
D(2) dopamine receptor0202
Alpha-1B adrenergic receptor0202
Alpha-2B adrenergic receptor0202
5-hydroxytryptamine receptor 1A0202
Muscarinic acetylcholine receptor M30202
Substance-K receptor0202
D(1A) dopamine receptor0202
D(4) dopamine receptor0202
UDP-glucuronosyltransferase 1A40001
Prostaglandin G/H synthase 10101
Thromboxane-A synthase 0101
Protein kinase C eta type0101
Histamine H2 receptor0202
Alpha-1D adrenergic receptor0202
Substance-P receptor0202
5-hydroxytryptamine receptor 2A0202
5-hydroxytryptamine receptor 2C0202
5-hydroxytryptamine receptor 1B0202
Adenosine receptor A2a0202
B2 bradykinin receptor0202
Adenosine receptor A10202
Sodium-dependent serotonin transporter0202
Melanocortin receptor 40202
Melanocortin receptor 50202
Mu-type opioid receptor0202
D(3) dopamine receptor0202
Delta-type opioid receptor0202
Kappa-type opioid receptor0202
5-hydroxytryptamine receptor 2B0202
Melanocortin receptor 30202
Alpha-1A adrenergic receptor0202
D(1A) dopamine receptor1001
5-hydroxytryptamine receptor 60202
Estrogen-related receptor gamma0101
Phospholipase D1 0101
Sodium-dependent dopamine transporter 0202
Protein kinase C epsilon type0101
Protein kinase C zeta type0101
Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform0101
Platelet-activating factor acetylhydrolase0101
Phospholipase D10101
Nuclear receptor subfamily 3 group C member 3 0202
Emopamil-binding protein-like0101
Angiotensin-converting enzyme 2 0011
7-dehydrocholesterol reductase0112
Chain X, Thyroid hormone receptor beta-10011
Chain X, Thyroid hormone receptor beta-10011
serine/threonine-protein kinase PLK11001
Solute carrier organic anion transporter family member 1A40001
Solute carrier organic anion transporter family member 1A50001
Rap guanine nucleotide exchange factor 32002
Transthyretin0102
Thyroid hormone receptor alpha0011
Thyroid hormone receptor beta0011
Proliferating cell nuclear antigen0101
Retinoic acid receptor RXR-alpha0022
Malate dehydrogenase, mitochondrial0101
Solute carrier organic anion transporter family member 1A20001
Solute carrier organic anion transporter family member 1A30001
Solute carrier organic anion transporter family member 4C10101
Monocarboxylate transporter 80001
Bile acid receptor0101
Solute carrier organic anion transporter family member 1C10001
Solute carrier organic anion transporter family member 1B10001
Solute carrier family 15 member 10203
Solute carrier family 15 member 10101
Solute carrier family 15 member 20101
Valacyclovir hydrolase0001
Chain A, Arginase 10101
Large neutral amino acids transporter small subunit 10101
Dipeptidyl peptidase 40101
Adenosylhomocysteinase0101
RNA-directed RNA polymerase 0112
parathyroid hormone/parathyroid hormone-related peptide receptor precursor1001
Albumin0011
Proprotein convertase subtilisin/kexin type 70101
Vitamin K epoxide reductase complex subunit 1-like protein 10101
Vitamin K epoxide reductase complex subunit 10101
Protease 0101
Vitamin K epoxide reductase complex subunit 1-like protein 10101
Vitamin K epoxide reductase complex subunit 1 0202
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]