Page last updated: 2024-09-27

Arthropathy, Neurogenic

Chronic progressive degeneration of the stress-bearing portion of a joint, with bizarre hypertrophic changes at the periphery. It is probably a complication of a variety of neurologic disorders, particularly TABES DORSALIS, involving loss of sensation, which leads to relaxation of supporting structures and chronic instability of the joint. (Dorland, 27th ed)

Synonyms(1)

Synonym
Arthropathy, Neurogenic

Research Excerpts

Overview

ExcerptReference
"Usually neurogenic arthropathy is associated with diabetes mellitus, syringomyelia or with infections."( Mäurer, M; Sommer, C, 1999)

Research

Studies (181)

TimeframeStudies, This Condition (%)All Conditions %
pre-199071 (39.23)23.3326
1990's28 (15.47)12.5806
2000's33 (18.23)18.1394
2010's46 (25.41)28.8240
2020's3 (1.66)9.53
DrugIndicatedRelationship StrengthStudiesTrials
histamine0low10
uric acid0low20
1,5-dihydroxyisoquinoline0low10
oxyquinoline0low10
alendronate0medium41
aspirin0low10
baclofen0low10
etidronate0medium11
hydroxychloroquine0low10
lidocaine0low10
indomethacin0low20
metronidazole0low10
ofloxacin0low10
pamidronate0medium61
thalidomide0low10
prednisolone0medium51
hydroxyproline0low30
prednisone0low20
penicillin g0low20
chloramphenicol0low10
carbostyril0low10
tyrosine0low10
colchicine0low10
oxacillin0low10
methylprednisolone0medium21
quinuclidines0low10
durapatite0low20
vancomycin0low10
tantalum0low20
technetium0low30
tricalcium phosphate0low30
calcium pyrophosphate0low50
trolamine salicylate0medium591
glutamic acid0low10
tobramycin0low10
substance p0low50
ribavirin0low10
pefloxacin0low10
fomesafen0low10
cephalosporin c0low20
fluorodeoxyglucose f180medium31
zoledronic acid0medium43
sr 1403330low10
rhenium-186 hedp0medium11
methotrexate0low20
cortisone0low20
3-nitrotyrosine0low10
noscapine0low10
clindamycin0low10
pyrophosphate0low50
capsaicin0low10
fusidic acid0low10
indium oxine0low10
nitinol0low10
osteoprotegerin0low70
bilirubin0low10
calcitriol0low10
thallium0low10
indium0low10
gallium0low10
cefepime0low10
gadolinium dtpa0low20
amoxicillin-potassium clavulanate combination0low10
seryl-leucyl-isoleucyl-glycyl--arginyl-leucinamide0low10
technetium tc 99m exametazime0low10
technetium tc 99m sestamibi0low10
ro13-99040low10
piperidines0low10
vasoactive intestinal peptide0low10
ascorbic acid0low10
technetium tc 99m sulfur colloid0low10
technetium tc 99m medronate0low100
exudates0low10

Protein Targets (874)

ProteinPotency MeasurementsInhibition MeasurementsActivation MeasurementsDrugs
Chain A, MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASE100010
Chain A, HADH2 protein8008
Chain B, HADH2 protein8008
Chain A, 2-oxoglutarate Oxygenase6006
Chain A, Ferritin light chain5005
acid sphingomyelinase3003
thioredoxin reductase110011
GLS protein9009
TDP1 protein180018
aldehyde dehydrogenase 1 family, member A1140014
IDH18008
euchromatic histone-lysine N-methyltransferase 2190019
Bloom syndrome protein isoform 15005
cytochrome P450 2C9 precursor5005
15-hydroxyprostaglandin dehydrogenase [NAD(+)] isoform 14004
flap endonuclease 17007
ras-related protein Rab-9A4004
peptidyl-prolyl cis-trans isomerase NIMA-interacting 14004
geminin170017
cytochrome P450 3A4 isoform 19009
lamin isoform A-delta10170017
Gamma-aminobutyric acid receptor subunit pi91010
Poly [ADP-ribose] polymerase 20101
Poly [ADP-ribose] polymerase 10101
Gamma-aminobutyric acid receptor subunit beta-191010
Gamma-aminobutyric acid receptor subunit delta91010
Gamma-aminobutyric acid receptor subunit gamma-291111
Gamma-aminobutyric acid receptor subunit alpha-591010
Gamma-aminobutyric acid receptor subunit alpha-391010
Gamma-aminobutyric acid receptor subunit gamma-191010
Gamma-aminobutyric acid receptor subunit alpha-291010
Gamma-aminobutyric acid receptor subunit alpha-491010
Gamma-aminobutyric acid receptor subunit gamma-391010
Gamma-aminobutyric acid receptor subunit alpha-691010
Histamine H2 receptor5016
Gamma-aminobutyric acid receptor subunit alpha-192112
Gamma-aminobutyric acid receptor subunit beta-391010
Gamma-aminobutyric acid receptor subunit beta-291111
Protein mono-ADP-ribosyltransferase PARP150101
GABA theta subunit91010
Gamma-aminobutyric acid receptor subunit epsilon91010
ATP-dependent phosphofructokinase7007
Chain A, Putative fructose-1,6-bisphosphate aldolase5005
Chain A, JmjC domain-containing histone demethylation protein 3A3003
phosphopantetheinyl transferase8008
bromodomain adjacent to zinc finger domain 2B5005
pyruvate kinase PKM isoform a1001
Glycoprotein hormones alpha chain1001
Guanine nucleotide-binding protein G4004
Tubulin--tyrosine ligase0202
Chain A, farnesyl pyrophosphate synthase0101
Geranylgeranyl pyrophosphate synthase0405
Farnesyl pyrophosphate synthase0606
Acetylcholinesterase0303
Hypoxanthine-guanine phosphoribosyltransferase0202
Farnesyl pyrophosphate synthase 0404
Farnesyl pyrophosphate synthase 0202
Chain A, TYROSYL-DNA PHOSPHODIESTERASE5005
acetylcholinesterase4004
hypoxia-inducible factor 1 alpha subunit7007
RAR-related orphan receptor gamma130013
SMAD family member 22002
ATAD5 protein, partial5005
Fumarate hydratase5005
USP1 protein, partial6006
NFKB1 protein, partial2002
PPM1D protein4004
SMAD family member 32002
Thrombopoietin3003
AR protein190019
caspase 7, apoptosis-related cysteine protease2002
hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)4004
thyroid stimulating hormone receptor7007
estrogen receptor 2 (ER beta)7007
nuclear receptor subfamily 1, group I, member 38008
progesterone receptor100010
EWS/FLI fusion protein110011
glucocorticoid receptor [Homo sapiens]110011
retinoic acid nuclear receptor alpha variant 1120012
retinoid X nuclear receptor alpha9009
estrogen-related nuclear receptor alpha150015
farnesoid X nuclear receptor100010
pregnane X nuclear receptor130013
estrogen nuclear receptor alpha210021
G5005
cytochrome P450 2D65005
polyprotein5005
peroxisome proliferator-activated receptor delta8008
peroxisome proliferator activated receptor gamma100010
caspase-32002
thyroid stimulating hormone receptor2002
v-jun sarcoma virus 17 oncogene homolog (avian)6006
Histone H2A.x6006
cytochrome P450 2D6 isoform 13003
cellular tumor antigen p53 isoform a3003
D(1A) dopamine receptor2002
chromobox protein homolog 1100010
thyroid hormone receptor beta isoform a5005
potassium voltage-gated channel subfamily H member 2 isoform d2002
thyroid hormone receptor beta isoform 2110011
heat shock protein beta-15005
huntingtin isoform 21001
mitogen-activated protein kinase 16006
serine/threonine-protein kinase mTOR isoform 12002
nuclear factor erythroid 2-related factor 2 isoform 1120012
urokinase-type plasminogen activator precursor3003
plasminogen precursor3003
urokinase plasminogen activator surface receptor precursor3003
nuclear receptor ROR-gamma isoform 17007
peripheral myelin protein 226006
survival motor neuron protein isoform d5005
muscarinic acetylcholine receptor M16006
lethal factor (plasmid)7007
Polyunsaturated fatty acid lipoxygenase ALOX15B1001
ATP-binding cassette sub-family C member 3018018
Multidrug resistance-associated protein 4018019
Voltage-dependent L-type calcium channel subunit alpha-1C0101
Solute carrier organic anion transporter family member 1A40101
Voltage-dependent L-type calcium channel subunit alpha-1F0303
5-hydroxytryptamine receptor 40202
Lysine-specific demethylase PHF20101
Bile salt export pump025025
Interferon beta8008
HLA class I histocompatibility antigen, B alpha chain 5005
Thyroid hormone receptor alpha0101
Receptor tyrosine-protein kinase erbB-20101
Cellular tumor antigen p53110011
Integrin beta-32114
Tyrosine-protein kinase Fyn0101
ATP-dependent translocase ABCB10202
Aldo-keto reductase family 1 member B10202
Muscarinic acetylcholine receptor M20404
Muscarinic acetylcholine receptor M40303
ATP-dependent translocase ABCB10416
Integrin alpha-IIb2114
Beta-1 adrenergic receptor0202
Muscarinic acetylcholine receptor M50303
Alpha-2A adrenergic receptor0404
Adenosine receptor A30303
Cytochrome P450 2C80101
Thyroid hormone receptor alpha0101
Thyroid hormone receptor beta0101
Muscarinic acetylcholine receptor M10303
Beta-3 adrenergic receptor0202
D(2) dopamine receptor0202
Androgen receptor0505
Alpha-1B adrenergic receptor0303
Lethal factor0101
Alpha-2B adrenergic receptor0314
Thyroid hormone receptor beta0101
Muscarinic acetylcholine receptor M30303
ATP-dependent translocase ABCB10202
Substance-K receptor0404
D(1A) dopamine receptor0202
D(4) dopamine receptor0202
Carnitine O-palmitoyltransferase 2, mitochondrial0101
Sodium-dependent noradrenaline transporter 0202
Histamine H2 receptor0325
Endothelin-1 receptor0202
5-hydroxytryptamine receptor 2A0202
5-hydroxytryptamine receptor 2C0202
Lysine-specific demethylase 5A0101
B2 bradykinin receptor0202
Sodium-dependent serotonin transporter0202
Melanocortin receptor 40202
C-8 sterol isomerase0101
Melanocortin receptor 50202
Mu-type opioid receptor0202
D(3) dopamine receptor0202
Sodium channel protein type 1 subunit alpha0101
Sodium channel protein type 4 subunit alpha0202
Squalene synthase0101
Delta-type opioid receptor0202
Kappa-type opioid receptor0202
5-hydroxytryptamine receptor 2B0202
C-C chemokine receptor type 20202
Melanocortin receptor 30202
Alpha-1A adrenergic receptor0303
D(1A) dopamine receptor1001
5-hydroxytryptamine receptor 60202
Carnitine O-palmitoyltransferase 1, liver isoform0101
C-C chemokine receptor type 40202
Spike glycoprotein6028
Sodium channel protein type 7 subunit alpha0101
Voltage-dependent L-type calcium channel subunit alpha-1D 0303
Sodium-dependent dopamine transporter 0202
Potassium voltage-gated channel subfamily H member 20505
Voltage-dependent L-type calcium channel subunit alpha-1S0303
Voltage-dependent L-type calcium channel subunit alpha-1C0303
Sodium channel protein type 5 subunit alpha0202
Squalene monooxygenase0101
3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase0101
Sodium channel protein type 9 subunit alpha0202
Lysine-specific demethylase 7A0101
Carnitine O-palmitoyltransferase 1, muscle isoform0101
Inositol hexakisphosphate kinase 15005
Canalicular multispecific organic anion transporter 1017017
Sodium channel protein type 2 subunit alpha0101
Ataxin-27007
Sigma non-opioid intracellular receptor 10314
NAD-dependent protein deacetylase sirtuin-3, mitochondrial0011
Sodium channel protein type 3 subunit alpha0202
Sodium channel protein type 11 subunit alpha0101
Histone lysine demethylase PHF80101
Sodium channel protein type 8 subunit alpha0101
Sodium channel protein type 10 subunit alpha0101
cytochrome P450 2C9, partial5005
Chain A, Hyaluronidase, phage associated0101
GLI family zinc finger 3130013
thioredoxin glutathione reductase4004
cytochrome P450 family 3 subfamily A polypeptide 49009
vitamin D (1,25- dihydroxyvitamin D3) receptor120012
nuclear factor erythroid 2-related factor 2 isoform 29009
lethal(3)malignant brain tumor-like protein 1 isoform I1001
Polyphenol oxidase 20102
Pancreatic alpha-amylase0202
Albumin0101
Urease0101
Prolyl 4-hydroxylase subunit alpha-10001
Tyrosinase0101
Hyaluronate lyase0101
Prolyl hydroxylase EGLN20001
Egl nine homolog 10001
Prolyl hydroxylase EGLN30001
Hypoxia-inducible factor 1-alpha inhibitor0001
Solute carrier family 23 member 10101
Chain A, Phospholipase A2 isoform 30011
GTP-binding protein (rab7)0011
ras protein, partial0011
interleukin 86006
hypothetical protein, conserved1001
glucocerebrosidase4004
Rac1 protein0011
cell division cycle 42 (GTP binding protein, 25kDa), partial0011
DNA polymerase iota isoform a (long)7007
DNA polymerase kappa isoform 16006
Prostaglandin-H2 D-isomerase0202
Solute carrier family 22 member 60303
Prostaglandin G/H synthase 1 0203
Prostaglandin G/H synthase 2 0203
Epidermal growth factor receptor0202
Carbonic anhydrase 10508
Carbonic anhydrase 205110
Fatty acid-binding protein, liver0202
Myeloperoxidase0101
Prostaglandin G/H synthase 10405
Seed linoleate 13S-lipoxygenase-10101
Glutathione hydrolase 1 proenzyme0101
Prostaglandin G/H synthase 10404
Adenosine receptor A10204
Adenosine receptor A2a0204
Substance-P receptor0404
Prostaglandin G/H synthase 20516
Urotensin-2 receptor0101
4-aminobutyrate aminotransferase, mitochondrial0101
Nuclear receptor ROR-gamma7007
Ras-related protein Rab-2A0011
Prostaglandin G/H synthase 20404
Rho-associated protein kinase 20202
Nicotinate phosphoribosyltransferase0202
Solute carrier family 22 member 200202
Solute carrier family 22 member 60202
Sigma non-opioid intracellular receptor 10011
regulator of G-protein signaling 44004
67.9K protein5005
activating transcription factor 64004
histone acetyltransferase KAT2A isoform 15005
Gamma-aminobutyric acid type B receptor subunit 20213
Gamma-aminobutyric acid type B receptor subunit 20202
Gamma-aminobutyric acid type B receptor subunit 10213
Gamma-aminobutyric acid type B receptor subunit 10101
Chain A, Cruzipain2002
Microtubule-associated protein tau6006
vitamin D3 receptor isoform VDRA6006
caspase-1 isoform alpha precursor3003
Caspase-72002
Inositol monophosphatase 12002
Solute carrier organic anion transporter family member 1B30406
Solute carrier organic anion transporter family member 1B10405
Chain A, Vitamin D Nuclear Receptor0011
Chain A, Beta-lactamase5005
Vitamin D3 receptor0011
Vitamin D-binding protein0011
Cytochrome P450 1A20102
Cytochrome P450 3A40405
Androgen receptor0314
Cytochrome P450 2D60101
Vitamin D3 receptor0124
Cytochrome P450 2C9 0304
Vitamin D3 receptor0113
Retinoic acid receptor RXR-alpha0011
Cytochrome P450 2C190202
Kappa-type opioid receptor0013
Vitamin D3 receptor0011
1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial0011
Vitamin D3 receptor0112
Transporter0101
Vitamin D3 receptor A0022
15-lipoxygenase, partial2002
cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a7007
transient receptor potential cation channel subfamily V member 11001
Transient receptor potential cation channel subfamily V member 10213
Lysine-specific histone demethylase 1A0101
Voltage-dependent calcium channel gamma-2 subunit9009
NADH-ubiquinone oxidoreductase chain 10101
Polyunsaturated fatty acid 5-lipoxygenase0101
Glutamate receptor 292112
Cannabinoid receptor 10101
Cannabinoid receptor 2 0101
D(2) dopamine receptor0022
Potassium voltage-gated channel subfamily A member 10112
Corticotropin-releasing factor receptor 20101
Transient receptor potential cation channel subfamily V member 10214
Transient receptor potential cation channel subfamily V member 40011
Transient receptor potential cation channel subfamily V member 20011
Chain A, serum paraoxonase0101
Carbonic anhydrase 120204
Carbonic anhydrase 30103
Neutrophil cytosol factor 10101
Carbonic anhydrase 40103
Carbonic anhydrase 60103
Carbonic anhydrase 5A, mitochondrial0103
Carbonic anhydrase 70103
Carbonic anhydrase 90204
Carbonic anhydrase 130102
Poly [ADP-ribose] polymerase tankyrase-20101
Carbonic anhydrase 140204
Carbonic anhydrase 5B, mitochondrial0103
Beta-lactamase 0002
Beta-lactamase 0002
Beta-lactamase 0002
Beta-lactamase 0002
Beta-lactamase 0002
Beta-lactamase 0002
Beta-lactamase 0002
Metallo-beta-lactamase type 20002
Metallo-beta-lactamase VIM-11 0002
Metallo-beta-lactamase VIM-20002
Metallo-beta-lactamase VIM-19 0002
Beta-lactamase 0002
Beta-lactamase 0002
Metallo-beta-lactamase0002
Beta-lactamase 0002
Beta-lactamase0002
Solute carrier family 22 member 50101
Beta-lactamase0002
Beta-lactamase0002
Beta-lactamase SHV-10002
Beta-lactamase0002
Beta-lactamase0002
Solute carrier family 15 member 10303
Beta-lactamase TEM0103
Beta-lactamase0002
B2 metallo-beta-lactamase 0002
Solute carrier family 15 member 20303
Metallo-beta-lactamase VIM-130002
Beta-lactamase 0002
Metallo-beta-lactamase VIM-20002
Beta-lactamase 0002
Metallo-beta-lactamase0001
Solute carrier family 15 member 20303
Beta-lactamase 0002
Beta-lactamase 0002
Metallo-b-lactamase 0002
BlaVIM-1 0002
Beta-lactamase 0002
Beta-lactamase 0002
Beta-lactamase 0002
Beta-lactamase class B VIM-2 0002
Beta-lactamase VIM-1 0002
aryl hydrocarbon receptor6006
nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105), isoform CRA_a4004
streptokinase A precursor0044
Dihydroxyacetone phosphate acyltransferase0001
30S ribosomal protein S60101
30S ribosomal protein S70101
50S ribosomal protein L150101
50S ribosomal protein L100101
50S ribosomal protein L110101
50S ribosomal protein L7/L120101
50S ribosomal protein L190101
50S ribosomal protein L10101
50S ribosomal protein L200101
50S ribosomal protein L270101
50S ribosomal protein L280101
50S ribosomal protein L290101
50S ribosomal protein L310101
50S ribosomal protein L31 type B0101
50S ribosomal protein L320101
50S ribosomal protein L330101
50S ribosomal protein L340101
50S ribosomal protein L350101
50S ribosomal protein L360101
30S ribosomal protein S100101
30S ribosomal protein S110101
30S ribosomal protein S120101
30S ribosomal protein S130101
30S ribosomal protein S160101
30S ribosomal protein S180101
30S ribosomal protein S190101
30S ribosomal protein S200101
30S ribosomal protein S20101
30S ribosomal protein S30101
30S ribosomal protein S40101
30S ribosomal protein S50101
30S ribosomal protein S80101
30S ribosomal protein S90101
50S ribosomal protein L130101
50S ribosomal protein L140101
50S ribosomal protein L160101
50S ribosomal protein L230101
30S ribosomal protein S150101
50S ribosomal protein L170101
50S ribosomal protein L210101
50S ribosomal protein L300101
50S ribosomal protein L60101
30S ribosomal protein S140101
30S ribosomal protein S170101
30S ribosomal protein S10101
50S ribosomal protein L180101
50S ribosomal protein L20101
50S ribosomal protein L30101
50S ribosomal protein L240101
50S ribosomal protein L40101
50S ribosomal protein L220101
50S ribosomal protein L50101
30S ribosomal protein S210101
50S ribosomal protein L250101
50S ribosomal protein L36 20101
Methionine--tRNA ligase, mitochondrial0011
Protein-arginine deiminase type-40202
Luciferase5005
endonuclease IV2002
PAX80001
pregnane X receptor3003
Smad32002
nuclear receptor subfamily 1, group I, member 23003
nuclear receptor subfamily 0 group B member 10101
cytochrome P450 2C19 precursor2002
atrial natriuretic peptide receptor 2 precursor2002
steroidogenic factor 10101
muscleblind-like protein 1 isoform 14004
neuropeptide S receptor isoform A2002
Solute carrier family 22 member 30203
Tubulin alpha-1A chain0213
Tubulin beta chain0213
Plasma kallikrein0003
Tubulin beta-4A chain0247
Tubulin beta chain0247
Tubulin alpha-3C chain0247
Serine/threonine-protein kinase pim-10101
Tubulin alpha-1B chain0247
Tubulin alpha-4A chain0247
Tubulin beta-4B chain0247
Vesicular acetylcholine transporter0101
Tubulin beta-3 chain0247
Tubulin beta-2A chain0247
Tubulin polymerization-promoting protein0011
Tubulin beta-8 chain0247
Tubulin beta-2B chain0303
Tubulin alpha-3E chain0247
Tubulin alpha-1A chain0247
Similar to alpha-tubulin isoform 1 0202
Similar to alpha-tubulin isoform 1 0202
CREB-binding protein1001
ATPase family AAA domain-containing protein 55005
Tubulin alpha-1C chain0247
Tubulin beta-6 chain0247
Tubulin beta-2B chain0247
Tubulin beta-1 chain0247
dopamine D1 receptor2002
peripheral myelin protein 22 isoform 13003
atrial natriuretic peptide receptor 1 precursor1001
M-phase phosphoprotein 83003
Glucocorticoid receptor08215
Sex hormone-binding globulin0011
Glycine receptor subunit alpha-10808
Corticosteroid-binding globulin0202
Glycine receptor subunit beta0808
Glycine receptor subunit alpha-20808
Glycine receptor subunit alpha-30808
TAR DNA-binding protein 433003
Multidrug and toxin extrusion protein 10404
apical membrane antigen 1, AMA12002
Type IV secretion-like conjugative transfer relaxase protein TraI 0101
Chain A, Type Iii Chloramphenicol Acetyltransferase0101
Bile salt export pump0303
Albumin0145
Estrogen receptor0011
Estrogen receptor beta0011
Canalicular multispecific organic anion transporter 10203
Broad substrate specificity ATP-binding cassette transporter ABCG20102
large T antigen0101
Chain A, GLUTAMATE RECEPTOR SUBUNIT 20101
Chain A, Glutamate Receptor Subunit 20101
Chain B, Glutamate Receptor Subunit 20101
Chain A, Slr1257 protein0011
Chain A, Glucosamine--fructose-6-phosphate aminotransferase [isomerizing]0101
glp-1 receptor, partial1001
beta-2 adrenergic receptor1001
Metabotropic glutamate receptor 80202
Metabotropic glutamate receptor 60113
Glutamate receptor ionotropic, NMDA 2D0101
Excitatory amino acid transporter 40101
Glutamate receptor ionotropic, NMDA 3B0101
Glutathione reductase, mitochondrial0202
Bifunctional aspartokinase/homoserine dehydrogenase 10101
Prothrombin0011
ATP-citrate synthase 0101
Glutamate receptor 10213
Glutamate receptor 30213
Glutamate receptor 40213
Glutamate receptor ionotropic, kainate 10213
Metabotropic glutamate receptor 10112
Metabotropic glutamate receptor 20011
Metabotropic glutamate receptor 30011
Metabotropic glutamate receptor 40112
Metabotropic glutamate receptor 50123
Metabotropic glutamate receptor 60011
Metabotropic glutamate receptor 70011
Glutamate receptor ionotropic, NMDA 1 0215
Glutamate receptor ionotropic, kainate 10112
Metabotropic glutamate receptor 50113
Glutamate receptor ionotropic, kainate 20213
Glutamate receptor 10213
Glutamate receptor 20213
Glutamate receptor 30112
Glutamate receptor ionotropic, kainate 30202
Excitatory amino acid transporter 10203
Excitatory amino acid transporter 20203
Excitatory amino acid transporter 30203
Metabotropic glutamate receptor 80011
Glutamate receptor 40213
Excitatory amino acid transporter 3 0001
Glutamate racemase0001
Metabotropic glutamate receptor 80112
Fatty-acid amide hydrolase 10101
Glutamate receptor ionotropic, NMDA 2A 0215
Glutamate receptor ionotropic, NMDA 2B0215
Glutamate receptor ionotropic, NMDA 2C0215
Glutamate receptor ionotropic, kainate 40202
Glutamate carboxypeptidase 20101
Glutamate receptor ionotropic, NMDA 10101
Glutamate receptor ionotropic, NMDA 2A0101
Glutamate receptor ionotropic, kainate 20112
Glutamate receptor ionotropic, kainate 30101
Glutamate receptor ionotropic, NMDA 2B0101
Metabotropic glutamate receptor 10113
Metabotropic glutamate receptor 20113
Metabotropic glutamate receptor 70113
Metabotropic glutamate receptor 30113
Metabotropic glutamate receptor 40113
Glutamate receptor ionotropic, NMDA 2C0101
Glutamate receptor ionotropic, kainate 50101
Carbonic anhydrase-like protein, putative0003
Glutamate receptor ionotropic, NMDA 2D0215
Glutamate receptor ionotropic, kainate 50202
Glutamate racemase0001
Prolyl 4-hydroxylase0101
Glutamate receptor ionotropic, NMDA 3A0101
Glutamate receptor ionotropic, NMDA 3B0215
Alpha-ketoglutarate-dependent dioxygenase FTO0101
Glutamate receptor ionotropic, NMDA 3A0215
Chain A, CARBONIC ANHYDRASE II0011
Chain A, Protein (female-specific Histamine Binding Protein 2)0011
aryl hydrocarbon receptor nuclear translocator0001
GALC protein2002
transforming acidic coiled-coil-containing protein 30001
Solute carrier family 22 member 20102
Solute carrier family 22 member 1 0001
Macrophage migration inhibitory factor0202
5-hydroxytryptamine receptor 1D0001
Histamine H1 receptor0134
Histamine H1 receptor0213
Histamine H1 receptor0224
Carbonic anhydrase0103
Carbonic anhydrase0003
Histamine H3 receptor0101
Histamine N-methyltransferase 0101
Glutaminyl-peptide cyclotransferase0202
Carbonic anhydrase 0003
Carbonic anhydrase0003
Carbonic anhydrase0003
Solute carrier family 22 member 10102
Carbonic anhydrase 0003
Equilibrative nucleoside transporter 40001
Histamine H4 receptor0123
Histamine H4 receptor0123
Histamine H4 receptor 0101
Carbonic anhydrase 40001
Carbonic anhydrase 150002
Carbonic anhydrase 130001
Histamine H4 receptor0123
Histamine H3 receptor0101
Carboxylic ester hydrolase 0001
Solute carrier family 22 member 20102
Histamine H3 receptor0123
Genome polyprotein 0101
Spike glycoprotein0022
Replicase polyprotein 1ab0022
Transmembrane protease serine 20022
Procathepsin L0123
Replicase polyprotein 1a0022
Replicase polyprotein 1ab0022
Replicase polyprotein 1ab0123
Replicase polyprotein 1ab0123
Alpha-2C adrenergic receptor0101
Alpha-1D adrenergic receptor0202
Sigma intracellular receptor 20101
Cyclic GMP-AMP synthase0101
Angiotensin-converting enzyme 2 0022
Toll-like receptor 90101
Toll-like receptor 70101
Neutral amino acid transporter A0101
Asc-type amino acid transporter 10101
Neutral amino acid transporter B(0)0101
Proton-coupled amino acid transporter 10101
Amino acid transporter0101
Chain A, membrane-associated prostaglandin E synthase-20101
Parkin2002
heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)1001
Prostaglandin E synthase0101
3',5'-cyclic-AMP phosphodiesterase 0101
Solute carrier organic anion transporter family member 2B1 0202
Cytochrome c oxidase subunit 20101
Phospholipase A2, major isoenzyme0101
Neuronal acetylcholine receptor subunit alpha-40101
Interleukin-80101
Neuronal acetylcholine receptor subunit beta-20101
Polyunsaturated fatty acid 5-lipoxygenase0102
Aldo-keto reductase family 1 member B10101
Aldo-keto reductase family 1 member B10101
Aldo-keto reductase family 1 member C40101
Prostaglandin G/H synthase 10101
Sodium-dependent dopamine transporter0101
Sodium- and chloride-dependent GABA transporter 10101
Thromboxane-A synthase 0101
Serum paraoxonase/arylesterase 10101
Indoleamine 2,3-dioxygenase 10101
Caspase-10001
Nitric oxide synthase, inducible0101
Prostaglandin E2 receptor EP3 subtype0101
Sodium- and chloride-dependent GABA transporter 20101
Sodium- and chloride-dependent GABA transporter 30101
Prostaglandin E2 receptor EP4 subtype0101
Multidrug resistance-associated protein 1 0102
Bifunctional epoxide hydrolase 20101
Prostaglandin G/H synthase 2 0101
Prostaglandin E2 receptor EP1 subtype0101
Peroxisome proliferator-activated receptor gamma0011
Aldo-keto reductase family 1 member C30202
Sodium- and chloride-dependent betaine transporter0101
C-X-C chemokine receptor type 30101
Aldo-keto reductase family 1 member C2 0101
Prostaglandin D2 receptor 0202
Solute carrier organic anion transporter family member 1A30102
Lactoylglutathione lyase0101
Aldo-keto reductase family 1 member C10101
Prostaglandin G/H synthase 20102
Uracil nucleotide/cysteinyl leukotriene receptor0101
Solute carrier family 22 member 60103
Solute carrier family 22 member 70001
Sigma intracellular receptor 20101
Prostaglandin E2 receptor EP2 subtype0101
Prostaglandin G/H synthase 1 0101
Solute carrier family 22 member 80304
Dehydrogenase/reductase SDR family member 90101
P2Y purinoceptor 120101
Cytosolic phospholipase A2 gamma0101
Prostaglandin D2 receptor 20112
Potassium channel subfamily K member 30101
Potassium channel subfamily K member 20101
Sodium channel protein type 1 subunit alpha0101
Sodium channel protein type 2 subunit alpha0101
Sodium channel protein type 3 subunit alpha0101
Potassium voltage-gated channel subfamily A member 50101
Potassium voltage-gated channel subfamily D member 20101
Potassium channel subfamily K member 180101
Chain B, DIHYDROFOLATE REDUCTASE0011
Chain B, DIHYDROFOLATE REDUCTASE0011
Chain B, DIHYDROFOLATE REDUCTASE0011
ClpP1001
Thymidylate synthase 0101
alpha-galactosidase2002
Thymidylate synthase 0101
polyunsaturated fatty acid lipoxygenase ALOX121001
transcriptional regulator ERG isoform 31001
importin subunit beta-1 isoform 11001
DNA polymerase beta1001
nuclear receptor coactivator 1 isoform 1 [Homo sapiens]0101
snurportin-11001
DNA polymerase eta isoform 11001
transactivating tegument protein VP16 [Human herpesvirus 1]0101
nuclear receptor coactivator 3 isoform a0101
Toll-like receptor 40101
Fatty-acid amide hydrolase 10101
ATP-binding cassette sub-family C member 30102
Dihydrofolate reductase0203
Dihydrofolate reductase0203
Dihydrofolate reductase 0101
Dihydrofolate reductase0101
Dihydrofolate reductase0101
Dihydrofolate reductase0203
Thymidylate synthase0101
Tyrosine-protein kinase ABL10011
Thymidylate synthase0202
Bifunctional dihydrofolate reductase-thymidylate synthase0101
Thymidylate synthase0202
5-hydroxytryptamine receptor 2C0102
High mobility group protein B10011
Dihydrofolate reductase0101
Thymidylate synthase0101
Dihydrofolate reductase0224
Glucose-6-phosphate 1-dehydrogenase0101
Bifunctional dihydrofolate reductase-thymidylate synthase0101
Folate receptor beta0101
5-hydroxytryptamine receptor 2A0101
Cytochrome P450 11B1, mitochondrial 0101
Folate receptor alpha0101
Dihydrofolate reductase0202
Histidine decarboxylase0101
Trifunctional purine biosynthetic protein adenosine-30101
Cyclin-dependent kinase 20011
Bifunctional purine biosynthesis protein ATIC0202
Delta-type opioid receptor0101
Mu-type opioid receptor0101
Kappa-type opioid receptor0101
Reduced folate transporter0202
Folylpolyglutamate synthase, mitochondrial0103
6-phosphogluconate dehydrogenase, decarboxylating0101
Dihydrofolate reductase0101
Pteridine reductase 10101
Folylpolyglutamate synthase, mitochondrial0103
Bifunctional dihydrofolate reductase-thymidylate synthase0101
Bifunctional dihydrofolate reductase-thymidylate synthase0101
Trifunctional purine biosynthetic protein adenosine-30101
Dihydrofolate reductase 0101
Dihydrofolate reductase0101
ATP-binding cassette sub-family C member 110001
Proton-coupled folate transporter0101
Multidrug resistance associated protein0102
Solute carrier family 22 member 110001
nonstructural protein 12002
Nuclear receptor subfamily 1 group I member 20011
Nuclear receptor subfamily 1 group I member 20011
Thioredoxin reductase 0101
Flavodoxin0001
Lanosterol 14-alpha demethylase0101
Tubulin beta 8B0011
DNA dC->dU-editing enzyme APOBEC-3G isoform 12002
arylsulfatase A3003
STE240001
parathyroid hormone/parathyroid hormone-related peptide receptor precursor1001
CAAX prenyl protease0001
Trypsin0001
DNA gyrase subunit A0102
DNA gyrase subunit B0102
DNA gyrase subunit B0102
DNA gyrase subunit A0102
Solute carrier family 22 member 80203
Beta-lactamase OXA-70001
Class D beta-lactamase0002
MecA 0101
Chain A, Bacterial leucyl aminopeptidase0101
90-kda heat shock protein beta HSP90 beta, partial0101
thyrotropin-releasing hormone receptor1001
Caspase-71001
caspase-31001
heat shock protein HSP 90-alpha isoform 20101
26S proteasome non-ATPase regulatory subunit 140101
Thermolysin0203
Cholinesterase0101
72 kDa type IV collagenase0202
Botulinum neurotoxin type A 0101
Indoleamine 2,3-dioxygenase 10101
Catechol O-methyltransferase0101
Catechol O-methyltransferase0101
Alpha-synuclein1001
Methionine aminopeptidase 20101
Methionine aminopeptidase 10101
Histone deacetylase 80011
Beta-lactamase 0001
Beta-lactamase 0001
Beta-lactamase 0001
Beta-lactamase 0001
Beta-lactamase 10001
Beta-lactamase SHV-10001
Beta-lactamase OXA-100001
Beta-lactamase 0001
Beta-lactamase 0001
Efflux transporter 0001
Beta-lactamase Toho-10001
Beta-lactamase 0001
Beta-lactamase 0001
Beta-lactamase 0001
Beta-lactamase 0001
Beta-lactamase IMP-1 0001
Carbapenem-hydrolyzing beta-lactamase KPC0001
Beta-lactamase 0001
Solute carrier family 22 member 80102
luciferase0001
Estrogen receptor0202
Progesterone receptor0203
Glucocorticoid receptor0112
Glucocorticoid receptor0011
Mineralocorticoid receptor 0213
Glutamine synthetase0011
Nociceptin receptor0011
Cytochrome P450 2J20101
Estrogen receptor beta0202
Chain A, dATP pyrophosphohydrolase0101
Chain A, Adenylate cyclase type 50101
Chain B, Adenylate cyclase type 20101
NS5 0011
glycogen synthase kinase-3 beta isoform 10011
Rap guanine nucleotide exchange factor 31001
Polymerase basic protein 20011
RNA-directed RNA polymerase catalytic subunit0011
Polymerase acidic protein0011
Adenosylhomocysteinase0002
Adenosine receptor A2a0101
Adenosine receptor A10101
Adenosine receptor A10101
Genome polyprotein0011
Proteinase-activated receptor 20011
Substance-P receptor0202
Neuromedin-K receptor0011
Substance-K receptor0112
Substance-P receptor0213
Neuromedin-K receptor0112
Substance-K receptor0101
Substance-K receptor0101
Growth hormone secretagogue receptor type 10011
Mas-related G-protein coupled receptor member X20011
Cereblon isoform 40202
cAMP-specific 3',5'-cyclic phosphodiesterase 4A0101
cAMP-specific 3',5'-cyclic phosphodiesterase 4B0101
cAMP-specific 3',5'-cyclic phosphodiesterase 4C0101
cAMP-specific 3',5'-cyclic phosphodiesterase 4D0101
DNA-binding protein Ikaros0001
DNA damage-binding protein 10112
Protein cereblon0214
Protein Rev 0011
Chain A, CHORISMATE MUTASE0101
Chain A, TYROSYL-tRNA SYNTHETASE0011
Large neutral amino acids transporter small subunit 10101
SLC16A10 protein0001
Monocarboxylate transporter 100001
Taste receptor type 2 member 140001
Chain A, Glycogen phosphorylase, liver form0011
Chain A, glycogen phosphorylase, liver form0011
Chain A, Glycogen phosphorylase, liver form0011
Chain A, Glycogen phosphorylase, liver form0011
Solute carrier family 2, facilitated glucose transporter member 90112
Guanine deaminase0101
60 kDa heat shock protein, mitochondrial0101
Alpha-2B adrenergic receptor0101
Alpha-2C adrenergic receptor0101
Alpha-2A adrenergic receptor0101
Alpha-1D adrenergic receptor0101
Sodium-dependent serotonin transporter0101
10 kDa heat shock protein, mitochondrial0101
D-alanyl-D-alanine dipeptidase0101
Thiosulfate sulfurtransferase0101
60 kDa chaperonin 0101
10 kDa chaperonin 0101
Transporter0101
Butyrophilin subfamily 3 member A10012
Matrix metalloproteinase-90101
Neutrophil collagenase0101
Farnesyl diphosphate synthase0101
Matrix metalloproteinase-140101
Geranylgeranyl pyrophosphate synthase0202
H0101
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]