Page last updated: 2024-09-27

Aortic Arch Syndrome

Conditions resulting from abnormalities in the arteries branching from the ASCENDING AORTA, the curved portion of the aorta. These syndromes are results of occlusion or abnormal blood flow to the head-neck or arm region leading to neurological defects and weakness in an arm. These syndromes are associated with vascular malformations; ATHEROSCLEROSIS; TRAUMA; and blood clots.

Synonyms(2)

Synonym
Aortic Arch Syndromes
Aortic Arch Syndrome

Research Excerpts

Research

Studies (172)

TimeframeStudies, This Condition (%)All Conditions %
pre-1990129 (75.00)23.3326
1990's17 (9.88)12.5806
2000's17 (9.88)18.1394
2010's8 (4.65)28.8240
2020's1 (0.58)9.53
DrugIndicatedRelationship StrengthStudiesTrials
dimethyl sulfoxide0low10
dalteparin0low10
niacin0low10
nitrous oxide0low10
theophylline0low10
amlodipine0low10
antipyrine0low10
aspirin0medium32
azathioprine0low20
bisoprolol0low10
caffeine0low10
verapamil0low10
chlorambucil0low20
chloroquine0low10
chlorothiazide0low20
chlorthalidone0low10
clonidine0low10
pentetic acid0low10
erythrosine0low30
fentanyl0low10
furosemide0low10
2-propanol0low60
methyl parathion0low10
apnea0low10
nitroglycerin0low10
propranolol0medium11
krypton0low10
thalidomide0low10
prednisolone0low240
thyroxine0low20
prednisone0low250
estrone0low10
dehydroepiandrosterone0low10
chloramphenicol0low10
phenylephrine0low10
methoxamine0low20
methylprednisolone0low40
triethylene glycol0low10
iodohippuric acid0low10
ephedrine0low10
betamethasone0low20
n-pentyl nitrite0low20
technetium0low40
barium sulfate0low20
trolamine salicylate0low80
gallium citrate0low10
propiconazole0low20
captopril0low30
fomesafen0low10
xenon radioisotopes0low30
fluorodeoxyglucose f180low30
fibrinogen0low10
p-methoxy-n-methylphenethylamine0low10
thromboxanes0low10
methotrexate0low10
proline0low20
technetium tc 99m pentetate0low10
angiotensin ii0low30
atropine0low10
cortisone0low20
retinol0low10
cocaine0low10
digoxin0low10
17-ketosteroids0low20
thromboxane b20medium21
phenylephrine hydrochloride0low20
oxymorphone0low10
morphine0low10
barium0low10
thallium0low20
indium0low10
naltrexone0low10
gallium0low10
methylnaltrexone0low10
phosphorus0low10
pregnanediol0low10
gadolinium dtpa0low10
sodium ethylxanthate0low20
salicylates0low10
warfarin0low40
cyclosporine0low10
cyclic gmp0low10
eye0low80

Protein Targets (904)

ProteinPotency MeasurementsInhibition MeasurementsActivation MeasurementsDrugs
hypoxia-inducible factor 1 alpha subunit6006
RAR-related orphan receptor gamma230023
GLI family zinc finger 3270027
AR protein340034
aldehyde dehydrogenase 1 family, member A1160016
retinoic acid nuclear receptor alpha variant 1260026
retinoid X nuclear receptor alpha200020
estrogen nuclear receptor alpha350035
peroxisome proliferator-activated receptor delta140014
cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a150015
activating transcription factor 69009
v-jun sarcoma virus 17 oncogene homolog (avian)120012
Histone H2A.x7007
thyroid hormone receptor beta isoform a110011
heat shock protein beta-18008
nuclear factor erythroid 2-related factor 2 isoform 1260026
lamin isoform A-delta10210021
Voltage-dependent calcium channel gamma-2 subunit9009
Glutamate receptor 29009
Chain A, Heat Shock Protein 900011
Chain A, GLUTAMINE PHOSPHORIBOSYLPYROPHOSPHATE AMIDOTRANSFERASE0011
Chain B, GLUTAMINE PHOSPHORIBOSYLPYROPHOSPHATE AMIDOTRANSFERASE0011
Chain A, EOSINOPHIL-DERIVED NEUROTOXIN0101
Chain A, EOSINOPHIL-DERIVED NEUROTOXIN0101
Chain A, EOSINOPHIL-DERIVED NEUROTOXIN0101
Chain A, Myosin Ie Heavy Chain0011
Chain A, Preprotein translocase secA0011
Chain A, Ribonuclease pancreatic0101
Chain A, Ribonuclease pancreatic0101
Chain A, Ribonuclease pancreatic0101
Chain A, Ribonuclease pancreatic0101
Chain A, Ribonuclease pancreatic0101
Chain A, Phosphoribosylformylglycinamidine synthase0101
Chain A, nucleoside diphosphate kinase A0011
Chain B, nucleoside diphosphate kinase A0011
Chain D, DNA polymerase III subunit gamma0011
Chain D, DNA polymerase III subunit gamma0011
Chain A [Pyruvate dehydrogenase [lipoamide]] kinase isozyme 30011
Chain A [Pyruvate dehydrogenase [lipoamide]] kinase isozyme 30011
Chain A, Kinesin-like protein KIF110101
regulator of G-protein signaling 48008
HPr kinase/phosphorylase0011
Mitogen-activated protein kinase kinase kinase 70011
ATP-dependent molecular chaperone HSP820001
Heat shock protein HSP 90-alpha0113
Heat shock protein HSP 90-beta0113
2-dehydropantoate 2-reductase0112
Heat shock 70 kDa protein 1A 0112
Endoplasmic reticulum chaperone BiP0011
Heat shock cognate 71 kDa protein0011
Pyruvate kinase PKM 0001
Pyruvate kinase PKLR 0001
Endoplasmin0001
Heat shock cognate 71 kDa protein0011
5'-nucleotidase0101
Mu-type opioid receptor09820
Delta-type opioid receptor09618
Kappa-type opioid receptor09518
Endoplasmin0112
P2Y purinoceptor 20011
Phosphatidylinositol 4-kinase alpha0202
P2X purinoceptor 10011
P2Y purinoceptor 10011
P2Y purinoceptor 10011
P2X purinoceptor 10011
P2X purinoceptor 40011
P2X purinoceptor 50011
P2X purinoceptor 60011
P2X purinoceptor 30011
Inositol monophosphatase 15005
Heat shock protein 75 kDa, mitochondrial0101
P2Y purinoceptor 60011
Phosphatidylinositol 4-kinase type 2-beta0202
P2Y purinoceptor 110011
Phosphatidylinositol 4-kinase type 2-alpha0202
P2Y purinoceptor 120011
Sensor protein kinase WalK0101
Phosphatidylinositol 4-kinase beta0202
P2X purinoceptor 20011
TDP1 protein270027
glucocorticoid receptor [Homo sapiens]250025
peroxisome proliferator activated receptor gamma190019
ATP-binding cassette sub-family C member 3021021
Multidrug resistance-associated protein 4021024
Bile salt export pump030030
Cellular tumor antigen p53170017
Thromboxane-A synthase 0202
Prostaglandin E2 receptor EP3 subtype0101
Prostaglandin E2 receptor EP4 subtype0112
Prostaglandin E2 receptor EP1 subtype0101
Prostacyclin receptor0112
Nuclear receptor subfamily 4 group A member 20022
Solute carrier organic anion transporter family member 2A10103
Nuclear receptor subfamily 4 group A member 20011
Nuclear receptor subfamily 4 group A member 20011
Prostaglandin E2 receptor EP2 subtype0112
Canalicular multispecific organic anion transporter 1020020
Solute carrier organic anion transporter family member 2A10002
Solute carrier organic anion transporter family member 2B10101
Solute carrier organic anion transporter family member 3A10001
Chain A, Ferritin light chain7007
acid sphingomyelinase2002
Smad33003
cytochrome P450 family 3 subfamily A polypeptide 4140014
G9009
cytochrome P450 2D69009
IDH19009
chromobox protein homolog 1130013
NEDD8-activating enzyme E1 regulatory subunit isoform a0101
NEDD8-conjugating enzyme Ubc120101
nuclear receptor ROR-gamma isoform 18008
geminin200020
histone acetyltransferase KAT2A isoform 16006
Voltage-dependent L-type calcium channel subunit alpha-1C0303
Potassium channel subfamily K member 20134
Interferon beta130013
HLA class I histocompatibility antigen, B alpha chain 9009
ATP-dependent translocase ABCB109118
Alpha-2A adrenergic receptor011517
Alpha-2C adrenergic receptor09414
Alpha-2B adrenergic receptor0516
Voltage-dependent L-type calcium channel subunit alpha-1C0202
Alpha-2C adrenergic receptor0516
Alpha-2A adrenergic receptor0516
Alpha-1D adrenergic receptor07211
Alpha-1A adrenergic receptor04410
Alpha-1B adrenergic receptor0338
5-hydroxytryptamine receptor 60617
Spike glycoprotein101112
Sodium-dependent dopamine transporter 0404
Voltage-dependent L-type calcium channel subunit alpha-1C0303
Potassium channel subfamily K member 2 0101
Inositol hexakisphosphate kinase 19009
cytochrome P450 2C9, partial9009
glucocerebrosidase3003
DNA polymerase kappa isoform 17007
Atrial natriuretic peptide receptor 30101
Type-1A angiotensin II receptor 0213
Type-1 angiotensin II receptor0011
Type-1B angiotensin II receptor0202
Type-1 angiotensin II receptor0336
Type-2 angiotensin II receptor0202
Type-2 angiotensin II receptor0202
ATAD5 protein, partial100010
USP1 protein, partial110011
nuclear receptor subfamily 1, group I, member 3180018
67.9K protein5005
nuclear factor erythroid 2-related factor 2 isoform 27007
Cytochrome P450 2C9 0819
Cytochrome P450 2J20505
Nicotinate phosphoribosyltransferase0303
thioredoxin reductase170017
Microtubule-associated protein tau8008
estrogen-related nuclear receptor alpha280028
arylsulfatase A130013
euchromatic histone-lysine N-methyltransferase 2220022
Bloom syndrome protein isoform 1120012
D(1A) dopamine receptor4004
neuropeptide S receptor isoform A2002
Chain A, MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASE100010
Chain A, TYROSYL-DNA PHOSPHODIESTERASE7007
Chain A, Phospholipase A2 isoform 30011
Chain A, HADH2 protein9009
Chain B, HADH2 protein9009
Chain A, 2-oxoglutarate Oxygenase8008
GTP-binding protein (rab7)0011
ras protein, partial0011
interleukin 86006
GLS protein100010
thyroid stimulating hormone receptor7007
hypothetical protein, conserved2002
EWS/FLI fusion protein130013
Rac1 protein0011
cell division cycle 42 (GTP binding protein, 25kDa), partial0011
15-hydroxyprostaglandin dehydrogenase [NAD(+)] isoform 13003
DNA polymerase iota isoform a (long)9009
muscarinic acetylcholine receptor M19009
lethal factor (plasmid)6006
Prostaglandin-H2 D-isomerase0101
Solute carrier family 22 member 60202
Prostaglandin G/H synthase 1 0101
Prostaglandin G/H synthase 2 0101
Epidermal growth factor receptor0101
Carbonic anhydrase 10608
Carbonic anhydrase 207110
Fatty acid-binding protein, liver0202
Integrin beta-34105
Myeloperoxidase0202
Prostaglandin G/H synthase 10303
Seed linoleate 13S-lipoxygenase-10101
Integrin alpha-IIb4105
Glutathione hydrolase 1 proenzyme0101
Prostaglandin G/H synthase 10303
Adenosine receptor A10507
Adenosine receptor A2a0419
Substance-P receptor0101
Prostaglandin G/H synthase 20505
Urotensin-2 receptor0101
4-aminobutyrate aminotransferase, mitochondrial0101
Nuclear receptor ROR-gamma7119
Ras-related protein Rab-2A0011
Gamma-aminobutyric acid receptor subunit alpha-183112
Prostaglandin G/H synthase 20202
Rho-associated protein kinase 20101
Solute carrier family 22 member 200202
Solute carrier family 22 member 60202
Sigma non-opioid intracellular receptor 10819
Sigma non-opioid intracellular receptor 10112
pregnane X nuclear receptor240024
cystic fibrosis transmembrane conductance regulator0101
DNA polymerase beta3003
short transient receptor potential channel 6 isoform 10011
Solute carrier family 22 member 1 011013
5-hydroxytryptamine receptor 40808
Muscarinic acetylcholine receptor M20429
Muscarinic acetylcholine receptor M40316
Muscarinic acetylcholine receptor M10417
Muscarinic acetylcholine receptor M30316
Muscarinic acetylcholine receptor M40316
Muscarinic acetylcholine receptor M50316
Muscarinic acetylcholine receptor M50316
Muscarinic acetylcholine receptor M20317
Muscarinic acetylcholine receptor M10429
Muscarinic acetylcholine receptor M10001
Muscarinic acetylcholine receptor M30428
5-hydroxytryptamine receptor 2C0819
Muscarinic acetylcholine receptor M40101
Histamine H2 receptor4005
5-hydroxytryptamine receptor 70505
Reverse transcriptase/RNaseH 0001
Muscarinic acetylcholine receptor0113
acetylcholinesterase7007
phosphopantetheinyl transferase100010
SMAD family member 26006
Fumarate hydratase2002
SMAD family member 36006
thioredoxin glutathione reductase6006
farnesoid X nuclear receptor130013
polyprotein2002
P531001
aryl hydrocarbon receptor100010
thyroid stimulating hormone receptor8008
peripheral myelin protein 22 isoform 17007
hemoglobin subunit beta1001
cellular tumor antigen p53 isoform a5005
thyroid hormone receptor beta isoform 2190019
peripheral myelin protein 228008
survival motor neuron protein isoform d8008
cytochrome P450 3A4 isoform 18008
M-phase phosphoprotein 86006
muscleblind-like protein 1 isoform 15005
Gamma-aminobutyric acid receptor subunit pi82111
Bile salt export pump0505
Gamma-aminobutyric acid receptor subunit beta-182111
Gamma-aminobutyric acid receptor subunit delta82111
Gamma-aminobutyric acid receptor subunit gamma-282111
Gamma-aminobutyric acid receptor subunit alpha-582111
Gamma-aminobutyric acid receptor subunit alpha-382111
Gamma-aminobutyric acid receptor subunit gamma-182111
Gamma-aminobutyric acid receptor subunit alpha-282111
Gamma-aminobutyric acid receptor subunit alpha-482111
Gamma-aminobutyric acid receptor subunit gamma-382111
Gamma-aminobutyric acid receptor subunit alpha-682111
Gamma-aminobutyric acid receptor subunit beta-382111
Gamma-aminobutyric acid receptor subunit beta-282111
GABA theta subunit82111
ATPase family AAA domain-containing protein 58008
Ataxin-2120012
Gamma-aminobutyric acid receptor subunit epsilon82111
Protein-arginine deiminase type-40202
pregnane X receptor6006
progesterone receptor150015
vitamin D (1,25- dihydroxyvitamin D3) receptor200020
nuclear receptor subfamily 1, group I, member 23003
galanin receptor type 30101
Glucocorticoid receptor010217
Glycine receptor subunit alpha-1010010
Glycine receptor subunit beta010010
Glycine receptor subunit alpha-2010010
Glycine receptor subunit alpha-3010010
ORF730022
Beta-2 adrenergic receptor0538
Beta-1 adrenergic receptor0437
Beta-3 adrenergic receptor0235
Beta-1 adrenergic receptor0202
Chain A, Glycogen Phosphorylase0101
Chain A, Glycogen phosphorylase, liver form0011
Chain A, glycogen phosphorylase, liver form0011
Chain A, Glycogen phosphorylase, liver form0011
Chain A, Glycogen phosphorylase, liver form0011
Chain A, Chitinase0101
atrial natriuretic peptide receptor 1 precursor2002
Glycogen phosphorylase, muscle form0101
Renin0303
Cholinesterase0202
Glycogen phosphorylase, liver form0101
Glycogen phosphorylase, muscle form0101
Replicase polyprotein 1ab0314
Adenosine receptor A30314
Replicase polyprotein 1ab0415
Amine oxidase [flavin-containing] A0303
Acetylcholinesterase0202
Amine oxidase [flavin-containing] B0404
cAMP-specific 3',5'-cyclic phosphodiesterase 4A0606
Adenosine receptor A30202
Adenosine receptor A2a05411
Adenosine receptor A2b0305
Adenosine receptor A2b0316
Adenosine receptor A10329
Vasopressin V2 receptor0002
Serine/threonine-protein kinase mTOR0202
Adenosine receptor A2a0202
Adenosine receptor A10303
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform 0202
DNA-dependent protein kinase catalytic subunit0101
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B0101
Adenylate cyclase type 10002
Chitotriosidase-10415
Serine-protein kinase ATM0101
Serine/threonine-protein kinase ATR0101
Adenosine receptor A2b0103
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C0101
Palmitoleoyl-protein carboxylesterase NOTUM0134
Endochitinase B10415
Phosphodiesterase 0101
Broad substrate specificity ATP-binding cassette transporter ABCG20416
Guanine deaminase0101
ATP-dependent phosphofructokinase120012
Chain A, angiotensin converting enzyme0101
Chain A, angiotensin converting enzyme0101
15-lipoxygenase, partial4004
Thrombopoietin3003
Metallo-beta-lactamase type 20112
transient receptor potential cation channel subfamily V member 11001
Prothrombin0101
Neprilysin0101
Neprilysin0101
Leukotriene A-4 hydrolase0213
EEF1AKMT4-ECE2 readthrough transcript protein0101
Angiotensin-converting enzyme 0314
Angiotensin-converting enzyme0203
Leukotriene A-4 hydrolase0101
Thymidine phosphorylase0011
Endothelin-converting enzyme 10101
Succinyl-diaminopimelate desuccinylase0202
Angiotensin-converting enzyme0202
Solute carrier family 15 member 10101
Beta-lactamase TEM0101
Mu-type opioid receptor08312
TAR DNA-binding protein 438008
Beta-lactamase 0203
Beta-lactamase 0202
Angiotensin-converting enzyme 2 0213
Beta-lactamase class B VIM-2 0112
Luciferase110011
NFKB1 protein, partial5005
GALC protein4004
caspase 7, apoptosis-related cysteine protease2002
hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)7007
bromodomain adjacent to zinc finger domain 2B5005
caspase-32002
vitamin D3 receptor isoform VDRA8008
potassium voltage-gated channel subfamily H member 2 isoform d5005
FAD-linked sulfhydryl oxidase ALR0001
urokinase-type plasminogen activator precursor2002
plasminogen precursor2002
urokinase plasminogen activator surface receptor precursor2002
Carbonic anhydrase 120305
Cytochrome P450 2D60304
Carbonic anhydrase 90305
Solute carrier organic anion transporter family member 1B30304
nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105), isoform CRA_a6006
streptokinase A precursor0011
Dihydroxyacetone phosphate acyltransferase0001
30S ribosomal protein S60101
30S ribosomal protein S70101
50S ribosomal protein L150101
Cytochrome P450 3A40819
50S ribosomal protein L100101
50S ribosomal protein L110101
50S ribosomal protein L7/L120101
50S ribosomal protein L190101
50S ribosomal protein L10101
50S ribosomal protein L200101
50S ribosomal protein L270101
50S ribosomal protein L280101
50S ribosomal protein L290101
50S ribosomal protein L310101
50S ribosomal protein L31 type B0101
50S ribosomal protein L320101
50S ribosomal protein L330101
50S ribosomal protein L340101
50S ribosomal protein L350101
50S ribosomal protein L360101
30S ribosomal protein S100101
30S ribosomal protein S110101
30S ribosomal protein S120101
30S ribosomal protein S130101
30S ribosomal protein S160101
30S ribosomal protein S180101
30S ribosomal protein S190101
30S ribosomal protein S200101
30S ribosomal protein S20101
30S ribosomal protein S30101
30S ribosomal protein S40101
30S ribosomal protein S50101
30S ribosomal protein S80101
30S ribosomal protein S90101
50S ribosomal protein L130101
50S ribosomal protein L140101
50S ribosomal protein L160101
50S ribosomal protein L230101
30S ribosomal protein S150101
50S ribosomal protein L170101
50S ribosomal protein L210101
50S ribosomal protein L300101
50S ribosomal protein L60101
30S ribosomal protein S140101
30S ribosomal protein S170101
30S ribosomal protein S10101
50S ribosomal protein L180101
50S ribosomal protein L20101
50S ribosomal protein L30101
50S ribosomal protein L240101
50S ribosomal protein L40101
50S ribosomal protein L220101
50S ribosomal protein L50101
30S ribosomal protein S210101
50S ribosomal protein L250101
50S ribosomal protein L36 20101
Methionine--tRNA ligase, mitochondrial0011
PPM1D protein4004
glucose-6-phosphate dehydrogenase-6-phosphogluconolactonase0101
Spike glycoprotein0112
Replicase polyprotein 1ab0112
glucose-6-phosphate 1-dehydrogenase isoform b0101
flap endonuclease 14004
Transmembrane protease serine 20112
Dihydrofolate reductase 0202
DNA ligase0101
Riboflavin-binding protein0011
Major prion protein0011
Amyloid-beta precursor protein0404
Histidine-rich protein PFHRP-II0102
Procathepsin L0112
Replicase polyprotein 1a0112
Replicase polyprotein 1ab0112
Spike glycoprotein0101
Ribosyldihydronicotinamide dehydrogenase [quinone]0101
Alpha-2B adrenergic receptor0629
DNA ligase 10101
Beta-secretase 10101
Calcium-dependent protein kinase 10011
MO15-related protein kinase Pfmrk 0101
DNA ligase A0101
Potassium voltage-gated channel subfamily H member 20707
Sigma intracellular receptor 20101
Phosphoethanolamine N-methyltransferase0101
Cysteine proteinase falcipain 2a 0101
Cysteine proteinase falcipain 2a 0101
Chain A, Beta-lactamase6006
nonstructural protein 16006
transcriptional regulator ERG isoform 33003
cystic fibrosis transmembrane conductance regulator ATP-binding cassette sub-family C member 70001
Carbonic anhydrase 30202
Carbonic anhydrase 40204
Carbonic anhydrase 60204
Carbonic anhydrase 5A, mitochondrial0204
Carbonic anhydrase 70204
Carbonic anhydrase 130204
Carbonic anhydrase 140204
Carbonic anhydrase 5B, mitochondrial0204
Chain A, Cruzipain4004
Beta-1 adrenergic receptor 0124
Alpha-1B adrenergic receptor 0022
cytochrome P450 2D6 isoform 12002
cytochrome P450 2C19 precursor2002
cytochrome P450 2C9 precursor2002
Membrane primary amine oxidase 0101
5-hydroxytryptamine receptor 3A0011
Solute carrier family 22 member 30203
5-hydroxytryptamine receptor 1A0303
Alpha-1B adrenergic receptor0314
Alpha-1A adrenergic receptor0123
D0202
D(3) dopamine receptor0303
5-hydroxytryptamine receptor 1A09111
Alpha-1D adrenergic receptor0314
D(1B) dopamine receptor0101
5-hydroxytryptamine receptor 1B0909
Alpha-2B adrenergic receptor0002
D(4) dopamine receptor0101
Delta-type opioid receptor08111
Alpha-1A adrenergic receptor0325
D(2) dopamine receptor0303
Alpha-2C adrenergic receptor0002
Alpha-2A adrenergic receptor0002
Alpha-2A adrenergic receptor0101
Nischarin0202
Solute carrier family 22 member 10101
Multidrug and toxin extrusion protein 10404
Nischarin0101
Chain A, CHIMERA OF IG KAPPA CHAIN: HUMAN CONSTANT REGION AND MOUSE VARIABLE REGION0011
Chain B, CHIMERA OF IG GAMMA-1 CHAIN: HUMAN CONSTANT REGION AND MOUSE VARIABLE REGION0011
Chain H, Fab M82G2, Heavy chain0011
Chain L, Fab M82G2, Light chain0011
Chain H, Fab M82g2, Heavy Chain0011
Chain L, Fab M82g2, Light Chain0011
Gamma-aminobutyric acid receptor subunit pi0101
Gamma-aminobutyric acid receptor subunit delta0101
Fatty acid-binding protein, heart0101
Muscarinic acetylcholine receptor M20112
5-hydroxytryptamine receptor 2C0304
Tryptophan 5-hydroxylase 10101
5-hydroxytryptamine receptor 2A0303
Gamma-aminobutyric acid receptor subunit alpha-10101
Gamma-aminobutyric acid receptor subunit beta-10101
Gamma-aminobutyric acid receptor subunit gamma-20101
Liver carboxylesterase 10001
Sodium-dependent noradrenaline transporter 0202
Sodium-dependent dopamine transporter0303
Gamma-aminobutyric acid receptor subunit beta-30101
5-hydroxytryptamine receptor 1D0101
5-hydroxytryptamine receptor 1F0101
5-hydroxytryptamine receptor 2B0202
5-hydroxytryptamine receptor 60101
Gamma-aminobutyric acid receptor subunit alpha-50101
Sodium-dependent serotonin transporter0808
Sodium-dependent serotonin transporter0304
5-hydroxytryptamine receptor 7 0101
Gamma-aminobutyric acid receptor subunit alpha-30101
5-hydroxytryptamine receptor 5A0101
5-hydroxytryptamine receptor 5B0101
Glutamate receptor ionotropic, NMDA 1 1203
5-hydroxytryptamine receptor 3A0101
Lysosomal Pro-X carboxypeptidase0101
Gamma-aminobutyric acid receptor subunit alpha-20101
Gamma-aminobutyric acid receptor subunit beta-20101
Gamma-aminobutyric acid receptor subunit alpha-40101
Gamma-aminobutyric acid receptor subunit epsilon0101
Glutamate receptor ionotropic, NMDA 2A 0101
Glutamate receptor ionotropic, NMDA 2B0101
Glutamate receptor ionotropic, NMDA 2C0101
cAMP-specific 3',5'-cyclic phosphodiesterase 4B0505
cAMP-specific 3',5'-cyclic phosphodiesterase 4D0505
Leukotriene B4 receptor 10101
Gamma-aminobutyric acid receptor subunit alpha-60101
Sodium-dependent dopamine transporter0202
Glutamate receptor ionotropic, NMDA 2D0101
5-hydroxytryptamine receptor 4 0101
Gamma-aminobutyric acid receptor subunit gamma-10101
Glutamate receptor ionotropic, NMDA 3B0101
Gamma-aminobutyric acid receptor subunit gamma-30101
5-hydroxytryptamine receptor 3B0101
Leukotriene B4 receptor 20101
Glutamate receptor ionotropic, NMDA 3A0101
Gamma-aminobutyric acid receptor subunit theta0101
Transporter0202
endonuclease IV4004
dopamine D1 receptor5005
Sex hormone-binding globulin0033
Corticosteroid-binding globulin0404
Potassium voltage-gated channel subfamily A member 10011
Phosphodiesterase 0303
Multidrug resistance-associated protein 50001
cGMP-inhibited 3',5'-cyclic phosphodiesterase B0202
cGMP-inhibited 3',5'-cyclic phosphodiesterase A0303
estrogen receptor 2 (ER beta)110011
Beta-glucuronidase0101
Beta-glucuronidase0101
Glucose-6-phosphate 1-dehydrogenase0404
Alpha-synuclein1203
G-protein coupled bile acid receptor 10011
Glucose-6-phosphate 1-dehydrogenase 0101
NPC1-like intracellular cholesterol transporter 10011
Chain A, ATP-DEPENDENT DNA HELICASE Q12002
PAX80001
STAT3, partial0101
alpha-galactosidase2002
NPC intracellular cholesterol transporter 1 precursor2002
tumor necrosis factor1001
parathyroid hormone/parathyroid hormone-related peptide receptor precursor5005
ras-related protein Rab-9A3003
signal transducer and activator of transcription 1-alpha/beta isoform alpha0101
Solute carrier organic anion transporter family member 1A40103
Sodium/potassium-transporting ATPase subunit alpha-1 0202
Sodium/potassium-transporting ATPase subunit beta-10202
Sodium/potassium-transporting ATPase subunit alpha-20101
Sodium/potassium-transporting ATPase subunit alpha-3 0101
ATP-dependent translocase ABCB10404
Sodium/potassium-transporting ATPase subunit beta-1 0101
Sodium/potassium-transporting ATPase subunit alpha-30101
Sodium/potassium-transporting ATPase subunit beta-20101
ATP-dependent translocase ABCB10405
Sodium/potassium-transporting ATPase subunit alpha-20202
Sodium/potassium-transporting ATPase subunit alpha-10101
Sodium/potassium-transporting ATPase subunit beta-30101
Sodium/potassium-transporting ATPase subunit gamma0101
Sodium/potassium-transporting ATPase subunit alpha-40101
Sodium/potassium-transporting ATPase subunit alpha-40101
Solute carrier organic anion transporter family member 4C10102
Solute carrier organic anion transporter family member 4C10001
Solute carrier organic anion transporter family member 1A40001
Solute carrier organic anion transporter family member 1B10304
Cereblon isoform 40404
Insulin-like growth factor-binding protein 50011
Choline O-acetyltransferase 0101
Protein cereblon0416
Adenylate cyclase 0101
Tyrosine-protein kinase Lck0101
Tyrosine-protein kinase Fyn0101
D(2) dopamine receptor0415
D(1A) dopamine receptor0314
5-hydroxytryptamine receptor 1D0101
5-hydroxytryptamine receptor 1B0314
5-hydroxytryptamine receptor 2A0617
D(3) dopamine receptor0505
5-hydroxytryptamine receptor 2B0819
5-hydroxytryptamine receptor 5A0101
Chain A, Putative fructose-1,6-bisphosphate aldolase4004
Genome polyprotein 0112
chaperonin-containing TCP-1 beta subunit homolog1001
thyrotropin-releasing hormone receptor3003
ubiquitin carboxyl-terminal hydrolase 2 isoform a3003
eyes absent homolog 2 isoform a1001
lethal(3)malignant brain tumor-like protein 1 isoform I1001
relaxin receptor 1 isoform 12002
Flavin reductase (NADPH)0011
large T antigen0101
hexokinase-4 isoform 11001
glucokinase regulatory protein1001
Rap guanine nucleotide exchange factor 32002
Estrogen receptor0416
Steryl-sulfatase0101
Aromatase0101
Polyunsaturated fatty acid lipoxygenase ALOX150202
17-beta-hydroxysteroid dehydrogenase type 10203
Androgen receptor0505
Mu-type opioid receptor09517
Solute carrier organic anion transporter family member 1A10101
Cytochrome P450 1B10101
Estrogen receptor beta0315
Ghrelin O-acyltransferase0101
Nuclear receptor subfamily 1 group I member 20033
D(4) dopamine receptor0101
Delta-type opioid receptor08312
Kappa-type opioid receptor07311
Histamine H1 receptor0101
Kappa-type opioid receptor09010
Mu-type opioid receptor06211
Sigma non-opioid intracellular receptor 10303
Albumin0134
Serum paraoxonase/arylesterase 10101
Corticosteroid 11-beta-dehydrogenase isozyme 10101
Corticosteroid 11-beta-dehydrogenase isozyme 10101
6-phosphogluconate dehydrogenase, decarboxylating0202
Holo-[acyl-carrier-protein] synthase0101
Sodium/bile acid cotransporter0202
G-protein coupled receptor 350112
CDGSH iron-sulfur domain-containing protein 10202
Parkin2002
pyruvate kinase1001
pyruvate kinase PKM isoform b1001
N-glycosylase/DNA lyase0101
Ornithine decarboxylase1001
Aspartate aminotransferase, cytoplasmic0101
Lactoperoxidase0101
Single-stranded DNA cytosine deaminase1001
Peptidylglycine alpha-amidating monooxygenase0001
Chain B, DIHYDROFOLATE REDUCTASE0011
Chain B, DIHYDROFOLATE REDUCTASE0011
Chain B, DIHYDROFOLATE REDUCTASE0011
ClpP1001
Thymidylate synthase 0101
Thymidylate synthase 0101
polyunsaturated fatty acid lipoxygenase ALOX121001
importin subunit beta-1 isoform 11001
nuclear receptor coactivator 1 isoform 1 [Homo sapiens]0101
snurportin-11001
peptidyl-prolyl cis-trans isomerase NIMA-interacting 12002
DNA polymerase eta isoform 12002
transactivating tegument protein VP16 [Human herpesvirus 1]0101
caspase-1 isoform alpha precursor1001
nuclear receptor coactivator 3 isoform a0101
Toll-like receptor 40101
Fatty-acid amide hydrolase 10101
ATP-binding cassette sub-family C member 30102
Dihydrofolate reductase0203
Dihydrofolate reductase0203
Dihydrofolate reductase0101
Dihydrofolate reductase0101
Dihydrofolate reductase0203
Thymidylate synthase0101
Tyrosine-protein kinase ABL10011
Thymidylate synthase0202
Bifunctional dihydrofolate reductase-thymidylate synthase0101
Thymidylate synthase0202
High mobility group protein B10011
Dihydrofolate reductase0101
Thymidylate synthase0101
Dihydrofolate reductase0224
Bifunctional dihydrofolate reductase-thymidylate synthase0101
Folate receptor beta0101
Cytochrome P450 11B1, mitochondrial 0101
Folate receptor alpha0101
Dihydrofolate reductase0202
Histidine decarboxylase0134
Trifunctional purine biosynthetic protein adenosine-30101
Cyclin-dependent kinase 20011
Bifunctional purine biosynthesis protein ATIC0202
Multidrug resistance-associated protein 1 0215
Reduced folate transporter0202
Folylpolyglutamate synthase, mitochondrial0103
Caspase-71001
Solute carrier organic anion transporter family member 1A30002
Dihydrofolate reductase0101
Pteridine reductase 10101
Folylpolyglutamate synthase, mitochondrial0103
Bifunctional dihydrofolate reductase-thymidylate synthase0101
Bifunctional dihydrofolate reductase-thymidylate synthase0101
Solute carrier family 22 member 60001
Canalicular multispecific organic anion transporter 10102
Trifunctional purine biosynthetic protein adenosine-30101
Dihydrofolate reductase 0101
Solute carrier family 22 member 80102
Dihydrofolate reductase0101
ATP-binding cassette sub-family C member 110001
Proton-coupled folate transporter0101
Multidrug resistance associated protein0102
Solute carrier family 22 member 110001
heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)2002
mitogen-activated protein kinase 13003
nuclear factor NF-kappa-B p105 subunit isoform 11001
Nuclear receptor subfamily 1 group I member 20011
Opioid receptor, delta 1b 0101
Acetylcholinesterase0101
Opioid receptor homologue0101
Acyl-CoA desaturase 10101
Translocator protein0011
Proteinase-activated receptor 10112
Kappa-type opioid receptor0427
UDP-glucuronosyltransferase 1A30001
Nociceptin receptor0101
Mu-type opioid receptor0101
Beta-2 adrenergic receptor0214
Mas-related G-protein coupled receptor member X20011
Mu-type opioid receptor0101
5-hydroxytryptamine receptor 3E0101
5-hydroxytryptamine receptor 3B0101
UDP-glucuronosyltransferase 1A1 0102
Nociceptin receptor0101
5-hydroxytryptamine receptor 3A0101
5-hydroxytryptamine receptor 3D0101
5-hydroxytryptamine receptor 3C0101
UDP-glucuronosyltransferase 1A80001
Chain A, JmjC domain-containing histone demethylation protein 3A1001
glp-1 receptor, partial6006
lysosomal alpha-glucosidase preproprotein3003
Polyphenol oxidase 20101
Neuronal acetylcholine receptor subunit alpha-42002
Cholesteryl ester transfer protein0101
Neuronal acetylcholine receptor subunit beta-22002
D-amino-acid oxidase0101
Xanthine dehydrogenase/oxidase0101
Hydroxycarboxylic acid receptor 30011
Nicotinamidase0101
Hydroxycarboxylic acid receptor 20011
Hydroxycarboxylic acid receptor 20213
D-aspartate oxidase0101
Hydroxycarboxylic acid receptor 20112
Polyunsaturated fatty acid lipoxygenase ALOX15B2002
vasopressin V1b receptor1001
cGMP-dependent 3',5'-cyclic phosphodiesterase0202
High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8A0101
cGMP-specific 3',5'-cyclic phosphodiesterase0101
Tumor necrosis factor0101
Disintegrin and metalloproteinase domain-containing protein 172002
Estrogen receptor 10101
fMet-Leu-Phe receptor0101
Prostaglandin G/H synthase 2 0101
Prostaglandin G/H synthase 1 0101
Cyclooxygenase-2 0101
POU domain, class 2, transcription factor 10001
Beta-1 adrenergic receptor0315
Alpha-1B adrenergic receptor0101
beta-2 adrenergic receptor1001
mu-type opioid receptor isoform MOR-10011
Vpr1001
5-hydroxytryptamine receptor 2A0011
luciferase0001
Progesterone receptor0203
Glucocorticoid receptor0112
Glucocorticoid receptor0011
Mineralocorticoid receptor 0213
Androgen receptor0202
Glutamine synthetase0011
Histamine H1 receptor0011
Nociceptin receptor0011
Glutamate 5-kinase0001
Neutral amino acid transporter A0101
Neutral amino acid transporter B(0)0101
Proton-coupled amino acid transporter 10101
Amino acid transporter0101
heat shock protein HSP 90-alpha isoform 20001
Guanine nucleotide-binding protein G2002
heat shock protein 90, putative0001
Cytochrome P450 1A20101
Beta-2 adrenergic receptor0203
Cytochrome P450 2C80202
Endothelin-1 receptor0112
Beta-3 adrenergic receptor0202
Neuromedin-K receptor0011
Cholecystokinin receptor type A0112
Cytochrome P450 2C190101
5-hydroxytryptamine receptor 70112
Vasopressin V1a receptor0112
Beta-2 adrenergic receptor0101
Sodium channel protein type 5 subunit alpha0202
Nuclear receptor subfamily 2 group E member 10022
Chain A, PLASMA RETINOL-BINDING PROTEIN PRECURSOR0011
Retinol-binding protein 40011
Beta-lactoglobulin0011
Chain A, Lysr-type Regulatory Protein0011
Chain A, Lysr-type Regulatory Protein0011
Chain A, Lysr-type Regulatory Protein0011
Chain A, 146aa long hypothetical transcriptional regulator0011
Chain A, Anthranilate phosphoribosyltransferase0101
Chain A, Anthranilate phosphoribosyltransferase0101
Chain A, Anthranilate phosphoribosyltransferase0101
Chain B, Anthranilate phosphoribosyltransferase0101
Chain C, Anthranilate phosphoribosyltransferase0101
Chain A, Anthranilate phosphoribosyltransferase0101
Anthranilate phosphoribosyltransferase0101
Caspase-71001
caspase-31001
cAMP-specific 3',5'-cyclic phosphodiesterase 4C0303
DNA-binding protein Ikaros0001
DNA damage-binding protein 10112
Chain A, Pyridoxal kinase0101
Chain A, Pyridoxal Kinase0101
Alkaline phosphatase, tissue-nonspecific isozyme0202
Intestinal-type alkaline phosphatase0101
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A 0101
cAMP-specific 3',5'-cyclic phosphodiesterase 4D 0101
cAMP-specific 3',5'-cyclic phosphodiesterase 4C0101
cAMP-specific 3',5'-cyclic phosphodiesterase 4B0101
Thyroid hormone receptor beta0101
Adenosine receptor A10202
Adenosine receptor A10101
cAMP-specific 3',5'-cyclic phosphodiesterase 4A0101
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A0101
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B0101
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B0101
High affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A0101
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C0101
Phospholipase A-2-activating protein0101
Gamma-aminobutyric acid receptor subunit alpha-10001
Gamma-aminobutyric acid receptor subunit beta-10001
Gamma-aminobutyric acid receptor subunit alpha-20001
Gamma-aminobutyric acid receptor subunit alpha-30001
Gamma-aminobutyric acid receptor subunit alpha-40001
Gamma-aminobutyric acid receptor subunit gamma-20001
Sodium- and chloride-dependent GABA transporter 10101
Sodium- and chloride-dependent GABA transporter 20101
Sodium- and chloride-dependent GABA transporter 30101
Sodium- and chloride-dependent betaine transporter0101
Fatty-acid amide hydrolase 10101
Chain X, Thyroid hormone receptor beta-10011
Chain X, Thyroid hormone receptor beta-10011
apical membrane antigen 1, AMA11001
serine/threonine-protein kinase PLK11001
Solute carrier organic anion transporter family member 1A50001
Transthyretin0102
Thyroid hormone receptor alpha0011
Thyroid hormone receptor beta0011
Proliferating cell nuclear antigen0101
Retinoic acid receptor RXR-alpha0022
Peroxisome proliferator-activated receptor gamma0022
Malate dehydrogenase, mitochondrial0101
Solute carrier organic anion transporter family member 1A20001
Monocarboxylate transporter 80001
Bile acid receptor0101
Solute carrier organic anion transporter family member 1C10001
huntingtin isoform 21001
Voltage-dependent L-type calcium channel subunit alpha-1F0101
Glycoprotein0101
Catechol O-methyltransferase0101
Potassium voltage-gated channel subfamily A member 30101
Histamine H2 receptor0202
Voltage-dependent L-type calcium channel subunit alpha-1D 0101
Voltage-dependent L-type calcium channel subunit alpha-1S0101
Chloroquine resistance transporter0101
Albumin0011
Proprotein convertase subtilisin/kexin type 70101
Vitamin K epoxide reductase complex subunit 1-like protein 10101
Vitamin K epoxide reductase complex subunit 10101
Protease 0101
Vitamin K epoxide reductase complex subunit 1-like protein 10101
Vitamin K epoxide reductase complex subunit 1 0202
Retinal dehydrogenase 20011
Retinal dehydrogenase 20101
Retinal dehydrogenase 10101
Aldehyde dehydrogenase, mitochondrial0101
Aldehyde dehydrogenase family 1 member A30101
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]