| Protein | Potency Measurements | Inhibition Measurements | Activation Measurements | Drugs |
|---|
| Chain A, MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASE | 3 | 0 | 0 | 3 |
| Chain A, TYROSYL-DNA PHOSPHODIESTERASE | 2 | 0 | 0 | 2 |
| Chain A, Ferritin light chain | 1 | 0 | 0 | 1 |
| interleukin 8 | 1 | 0 | 0 | 1 |
| acetylcholinesterase | 3 | 0 | 0 | 3 |
| thioredoxin reductase | 2 | 0 | 0 | 2 |
| phosphopantetheinyl transferase | 1 | 0 | 0 | 1 |
| RAR-related orphan receptor gamma | 7 | 0 | 0 | 7 |
| SMAD family member 2 | 3 | 0 | 0 | 3 |
| ATAD5 protein, partial | 1 | 0 | 0 | 1 |
| Fumarate hydratase | 1 | 0 | 0 | 1 |
| SMAD family member 3 | 3 | 0 | 0 | 3 |
| TDP1 protein | 7 | 0 | 0 | 7 |
| GLI family zinc finger 3 | 5 | 0 | 0 | 5 |
| Microtubule-associated protein tau | 1 | 0 | 0 | 1 |
| AR protein | 7 | 0 | 0 | 7 |
| thioredoxin glutathione reductase | 2 | 0 | 0 | 2 |
| nuclear receptor subfamily 1, group I, member 3 | 5 | 0 | 0 | 5 |
| EWS/FLI fusion protein | 2 | 0 | 0 | 2 |
| glucocorticoid receptor [Homo sapiens] | 7 | 0 | 0 | 7 |
| retinoic acid nuclear receptor alpha variant 1 | 4 | 0 | 0 | 4 |
| retinoid X nuclear receptor alpha | 5 | 0 | 0 | 5 |
| estrogen-related nuclear receptor alpha | 8 | 0 | 0 | 8 |
| farnesoid X nuclear receptor | 3 | 0 | 0 | 3 |
| pregnane X nuclear receptor | 7 | 0 | 0 | 7 |
| estrogen nuclear receptor alpha | 8 | 0 | 0 | 8 |
| G | 3 | 0 | 0 | 3 |
| polyprotein | 1 | 0 | 0 | 1 |
| P53 | 1 | 0 | 0 | 1 |
| peroxisome proliferator-activated receptor delta | 4 | 0 | 0 | 4 |
| peroxisome proliferator activated receptor gamma | 5 | 0 | 0 | 5 |
| arylsulfatase A | 1 | 0 | 0 | 1 |
| IDH1 | 2 | 0 | 0 | 2 |
| euchromatic histone-lysine N-methyltransferase 2 | 3 | 0 | 0 | 3 |
| aryl hydrocarbon receptor | 5 | 0 | 0 | 5 |
| cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a | 7 | 0 | 0 | 7 |
| thyroid stimulating hormone receptor | 2 | 0 | 0 | 2 |
| activating transcription factor 6 | 3 | 0 | 0 | 3 |
| v-jun sarcoma virus 17 oncogene homolog (avian) | 5 | 0 | 0 | 5 |
| Histone H2A.x | 3 | 0 | 0 | 3 |
| Bloom syndrome protein isoform 1 | 1 | 0 | 0 | 1 |
| peripheral myelin protein 22 isoform 1 | 1 | 0 | 0 | 1 |
| hemoglobin subunit beta | 1 | 0 | 0 | 1 |
| cellular tumor antigen p53 isoform a | 1 | 0 | 0 | 1 |
| thyroid hormone receptor beta isoform 2 | 6 | 0 | 0 | 6 |
| heat shock protein beta-1 | 2 | 0 | 0 | 2 |
| nuclear factor erythroid 2-related factor 2 isoform 1 | 6 | 0 | 0 | 6 |
| DNA polymerase iota isoform a (long) | 2 | 0 | 0 | 2 |
| geminin | 6 | 0 | 0 | 6 |
| peripheral myelin protein 22 | 3 | 0 | 0 | 3 |
| survival motor neuron protein isoform d | 2 | 0 | 0 | 2 |
| cytochrome P450 3A4 isoform 1 | 2 | 0 | 0 | 2 |
| M-phase phosphoprotein 8 | 1 | 0 | 0 | 1 |
| muscleblind-like protein 1 isoform 1 | 3 | 0 | 0 | 3 |
| muscarinic acetylcholine receptor M1 | 1 | 0 | 0 | 1 |
| lamin isoform A-delta10 | 4 | 0 | 0 | 4 |
| Gamma-aminobutyric acid receptor subunit pi | 2 | 0 | 1 | 3 |
| ATP-binding cassette sub-family C member 3 | 0 | 4 | 0 | 4 |
| Multidrug resistance-associated protein 4 | 0 | 4 | 0 | 4 |
| Bile salt export pump | 0 | 1 | 0 | 1 |
| Voltage-dependent calcium channel gamma-2 subunit | 4 | 0 | 0 | 4 |
| Bile salt export pump | 0 | 5 | 0 | 5 |
| Interferon beta | 4 | 0 | 0 | 4 |
| HLA class I histocompatibility antigen, B alpha chain | 3 | 0 | 0 | 3 |
| Cellular tumor antigen p53 | 7 | 0 | 0 | 7 |
| Gamma-aminobutyric acid receptor subunit beta-1 | 2 | 0 | 1 | 3 |
| Gamma-aminobutyric acid receptor subunit delta | 2 | 0 | 1 | 3 |
| Gamma-aminobutyric acid receptor subunit gamma-2 | 2 | 0 | 1 | 3 |
| Glutamate receptor 2 | 4 | 1 | 0 | 5 |
| Gamma-aminobutyric acid receptor subunit alpha-5 | 2 | 0 | 1 | 3 |
| Gamma-aminobutyric acid receptor subunit alpha-3 | 2 | 0 | 1 | 3 |
| Gamma-aminobutyric acid receptor subunit gamma-1 | 2 | 0 | 1 | 3 |
| Gamma-aminobutyric acid receptor subunit alpha-2 | 2 | 0 | 1 | 3 |
| Gamma-aminobutyric acid receptor subunit alpha-4 | 2 | 0 | 1 | 3 |
| Gamma-aminobutyric acid receptor subunit gamma-3 | 2 | 0 | 1 | 3 |
| Gamma-aminobutyric acid receptor subunit alpha-6 | 2 | 0 | 1 | 3 |
| Nuclear receptor ROR-gamma | 2 | 0 | 0 | 2 |
| Gamma-aminobutyric acid receptor subunit alpha-1 | 2 | 0 | 1 | 3 |
| Gamma-aminobutyric acid receptor subunit beta-3 | 2 | 0 | 1 | 3 |
| Gamma-aminobutyric acid receptor subunit beta-2 | 2 | 0 | 1 | 3 |
| GABA theta subunit | 2 | 0 | 1 | 3 |
| Inositol hexakisphosphate kinase 1 | 3 | 0 | 0 | 3 |
| Canalicular multispecific organic anion transporter 1 | 0 | 5 | 0 | 6 |
| ATPase family AAA domain-containing protein 5 | 5 | 0 | 0 | 5 |
| Ataxin-2 | 5 | 0 | 0 | 5 |
| Gamma-aminobutyric acid receptor subunit epsilon | 2 | 0 | 1 | 3 |
| Protein-arginine deiminase type-4 | 0 | 1 | 0 | 1 |
| cytochrome P450 2C9, partial | 3 | 0 | 0 | 3 |
| Vasopressin V2 receptor | 0 | 2 | 2 | 4 |
| Oxytocin receptor | 0 | 2 | 3 | 5 |
| Vasopressin V1a receptor | 0 | 3 | 2 | 5 |
| Vasopressin V1b receptor | 0 | 2 | 2 | 4 |
| Translocator protein | 0 | 1 | 0 | 1 |
| Vasopressin V2 receptor | 0 | 2 | 1 | 3 |
| glp-1 receptor, partial | 3 | 0 | 0 | 3 |
| hypoxia-inducible factor 1 alpha subunit | 3 | 0 | 0 | 3 |
| caspase 7, apoptosis-related cysteine protease | 1 | 0 | 0 | 1 |
| progesterone receptor | 6 | 0 | 0 | 6 |
| 67.9K protein | 2 | 0 | 0 | 2 |
| vitamin D (1,25- dihydroxyvitamin D3) receptor | 5 | 0 | 0 | 5 |
| caspase-3 | 1 | 0 | 0 | 1 |
| LMP1 [Human herpesvirus 4] | 0 | 0 | 0 | 1 |
| nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105), isoform CRA_a | 3 | 0 | 0 | 3 |
| chromobox protein homolog 1 | 3 | 0 | 0 | 3 |
| nuclear factor erythroid 2-related factor 2 isoform 2 | 5 | 0 | 0 | 5 |
| nuclear receptor coactivator 1 isoform 1 [Homo sapiens] | 0 | 1 | 0 | 1 |
| urokinase-type plasminogen activator precursor | 2 | 0 | 0 | 2 |
| plasminogen precursor | 2 | 0 | 0 | 2 |
| urokinase plasminogen activator surface receptor precursor | 2 | 0 | 0 | 2 |
| transactivating tegument protein VP16 [Human herpesvirus 1] | 0 | 1 | 0 | 1 |
| nuclear receptor coactivator 3 isoform a | 0 | 1 | 0 | 1 |
| Prothrombin | 0 | 0 | 1 | 2 |
| Regulatory protein E2 | 0 | 0 | 1 | 1 |
| ATP-dependent translocase ABCB1 | 0 | 1 | 0 | 1 |
| ATP-dependent translocase ABCB1 | 0 | 2 | 0 | 3 |
| Cytochrome P450 3A4 | 0 | 1 | 0 | 1 |
| DNA topoisomerase 1 | 0 | 1 | 0 | 2 |
| DNA topoisomerase 2-alpha | 0 | 1 | 1 | 7 |
| Cytochrome P450 2C9 | 0 | 2 | 0 | 2 |
| Polyunsaturated fatty acid lipoxygenase ALOX15 | 0 | 1 | 0 | 1 |
| DNA topoisomerase 2 | 0 | 0 | 0 | 1 |
| ATP-dependent translocase ABCB1 | 0 | 1 | 0 | 1 |
| UDP-glucuronosyltransferase 1A1 | 0 | 1 | 0 | 3 |
| Serum paraoxonase/arylesterase 1 | 0 | 1 | 0 | 1 |
| Glutamate receptor ionotropic, NMDA 1 | 0 | 0 | 0 | 1 |
| Caspase-3 | 0 | 1 | 0 | 1 |
| Glutamate receptor ionotropic, NMDA 2A | 0 | 0 | 0 | 1 |
| Glutamate receptor ionotropic, NMDA 2B | 0 | 0 | 0 | 1 |
| Glutamate receptor ionotropic, NMDA 2C | 0 | 0 | 0 | 1 |
| DNA topoisomerase 2-alpha | 0 | 0 | 0 | 1 |
| DNA topoisomerase 2-beta | 0 | 1 | 1 | 8 |
| Glutamate receptor ionotropic, NMDA 2D | 0 | 0 | 0 | 1 |
| Tubulin beta-2B chain | 0 | 1 | 0 | 1 |
| Integrase | 0 | 1 | 0 | 1 |
| Similar to alpha-tubulin isoform 1 | 0 | 1 | 0 | 1 |
| Similar to alpha-tubulin isoform 1 | 0 | 1 | 0 | 1 |
| Glutamate receptor ionotropic, NMDA 3B | 0 | 0 | 0 | 1 |
| Solute carrier organic anion transporter family member 1B3 | 0 | 2 | 0 | 3 |
| Glutamate receptor ionotropic, NMDA 3A | 0 | 0 | 0 | 1 |
| PPM1D protein | 1 | 0 | 0 | 1 |
| hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 2 | 0 | 0 | 2 |
| nonstructural protein 1 | 1 | 0 | 0 | 1 |
| bromodomain adjacent to zinc finger domain 2B | 1 | 0 | 0 | 1 |
| nuclear receptor subfamily 1, group I, member 2 | 2 | 0 | 0 | 2 |
| Nuclear receptor subfamily 1 group I member 2 | 0 | 0 | 2 | 2 |
| Glucocorticoid receptor | 0 | 6 | 2 | 13 |
| Glycine receptor subunit alpha-1 | 0 | 6 | 0 | 6 |
| Androgen receptor | 0 | 3 | 0 | 3 |
| Glycine receptor subunit beta | 0 | 6 | 0 | 6 |
| Glycine receptor subunit alpha-2 | 0 | 6 | 0 | 6 |
| Glycine receptor subunit alpha-3 | 0 | 6 | 0 | 6 |
| Nuclear receptor subfamily 1 group I member 2 | 0 | 0 | 1 | 1 |
| ATP-dependent phosphofructokinase | 1 | 0 | 0 | 1 |
| Chain A, Inosine-5'-Monophosphate Dehydrogenase 2 | 0 | 1 | 0 | 1 |
| Chain A, HADH2 protein | 2 | 0 | 0 | 2 |
| Chain B, HADH2 protein | 2 | 0 | 0 | 2 |
| Chain A, 2-oxoglutarate Oxygenase | 1 | 0 | 0 | 1 |
| aldehyde dehydrogenase 1 family, member A1 | 2 | 0 | 0 | 2 |
| estrogen receptor 2 (ER beta) | 2 | 0 | 0 | 2 |
| 15-hydroxyprostaglandin dehydrogenase [NAD(+)] isoform 1 | 1 | 0 | 0 | 1 |
| lethal factor (plasmid) | 1 | 0 | 0 | 1 |
| UDP-glucuronosyltransferase 1A9 | 0 | 0 | 0 | 1 |
| Inosine-5'-monophosphate dehydrogenase 2 | 0 | 2 | 0 | 2 |
| Glutamate receptor 1 | 0 | 1 | 0 | 1 |
| Glutamate receptor 3 | 0 | 1 | 0 | 1 |
| Glutamate receptor 4 | 0 | 1 | 0 | 1 |
| Inosine-5'-monophosphate dehydrogenase 1 | 0 | 2 | 0 | 2 |
| Sodium-dependent serotonin transporter | 0 | 1 | 0 | 1 |
| Peroxisome proliferator-activated receptor gamma | 0 | 0 | 5 | 5 |
| Alpha-synuclein | 1 | 0 | 0 | 1 |
| TAR DNA-binding protein 43 | 1 | 0 | 0 | 1 |
| Inosine-5'-monophosphate dehydrogenase | 0 | 1 | 0 | 2 |
| UDP-glucuronosyltransferase 1A7 | 0 | 0 | 0 | 1 |
| UDP-glucuronosyltransferase 1A10 | 0 | 0 | 0 | 1 |
| UDP-glucuronosyltransferase 1A8 | 0 | 0 | 0 | 1 |
| Sodium channel protein type 1 subunit alpha | 0 | 1 | 0 | 1 |
| Sodium channel protein type 2 subunit alpha | 0 | 1 | 0 | 1 |
| Sodium channel protein type 3 subunit alpha | 0 | 1 | 0 | 1 |
| Vasopressin V1a receptor | 0 | 1 | 0 | 1 |
| Vasopressin V1b receptor | 0 | 1 | 0 | 1 |
| Oxytocin receptor | 0 | 1 | 0 | 1 |
| Oxytocin receptor | 0 | 0 | 1 | 1 |
| Potassium voltage-gated channel subfamily H member 2 | 0 | 1 | 0 | 1 |
| luciferase | 0 | 0 | 0 | 1 |
| cytochrome P450 family 3 subfamily A polypeptide 4 | 3 | 0 | 0 | 3 |
| Fatty acid-binding protein, liver | 0 | 1 | 0 | 1 |
| Estrogen receptor | 0 | 2 | 0 | 2 |
| Progesterone receptor | 0 | 2 | 0 | 3 |
| Glucocorticoid receptor | 0 | 1 | 1 | 2 |
| Glucocorticoid receptor | 0 | 0 | 1 | 1 |
| Corticosteroid-binding globulin | 0 | 1 | 0 | 1 |
| Mineralocorticoid receptor | 0 | 2 | 1 | 3 |
| Androgen receptor | 0 | 3 | 0 | 3 |
| Glutamine synthetase | 0 | 0 | 1 | 1 |
| Histamine H1 receptor | 0 | 0 | 1 | 1 |
| Prostaglandin G/H synthase 2 | 0 | 1 | 0 | 1 |
| Nociceptin receptor | 0 | 0 | 1 | 1 |
| Cytochrome P450 2J2 | 0 | 1 | 0 | 1 |
| Estrogen receptor beta | 0 | 2 | 0 | 2 |
| pregnane X receptor | 1 | 0 | 0 | 1 |
| vitamin D3 receptor isoform VDRA | 1 | 0 | 0 | 1 |
| nuclear receptor ROR-gamma isoform 1 | 1 | 0 | 0 | 1 |
| flap endonuclease 1 | 1 | 0 | 0 | 1 |
| Chain X, Thyroid hormone receptor beta-1 | 0 | 0 | 2 | 2 |
| Chain X, Thyroid hormone receptor beta-1 | 0 | 0 | 2 | 2 |
| USP1 protein, partial | 2 | 0 | 0 | 2 |
| apical membrane antigen 1, AMA1 | 2 | 0 | 0 | 2 |
| thyroid hormone receptor beta isoform a | 2 | 0 | 0 | 2 |
| serine/threonine-protein kinase PLK1 | 1 | 0 | 0 | 1 |
| peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 | 1 | 0 | 0 | 1 |
| DNA polymerase eta isoform 1 | 1 | 0 | 0 | 1 |
| DNA polymerase kappa isoform 1 | 1 | 0 | 0 | 1 |
| Solute carrier organic anion transporter family member 1A4 | 0 | 1 | 0 | 3 |
| Solute carrier organic anion transporter family member 1A5 | 0 | 0 | 0 | 2 |
| Rap guanine nucleotide exchange factor 3 | 1 | 0 | 0 | 1 |
| Transthyretin | 0 | 1 | 0 | 3 |
| Thyroid hormone receptor alpha | 0 | 2 | 3 | 5 |
| Thyroid hormone receptor beta | 0 | 2 | 3 | 5 |
| Proliferating cell nuclear antigen | 0 | 2 | 0 | 2 |
| Retinoic acid receptor RXR-alpha | 0 | 0 | 2 | 2 |
| Malate dehydrogenase, mitochondrial | 0 | 1 | 0 | 1 |
| Solute carrier organic anion transporter family member 1A2 | 0 | 0 | 0 | 2 |
| Solute carrier organic anion transporter family member 1A3 | 0 | 0 | 0 | 2 |
| Solute carrier organic anion transporter family member 4C1 | 0 | 1 | 0 | 2 |
| Monocarboxylate transporter 8 | 0 | 0 | 0 | 1 |
| Bile acid receptor | 0 | 1 | 0 | 1 |
| Solute carrier organic anion transporter family member 1C1 | 0 | 0 | 0 | 1 |
| Solute carrier organic anion transporter family member 1B1 | 0 | 0 | 0 | 2 |
| glucocerebrosidase | 1 | 0 | 0 | 1 |
| neuropeptide S receptor isoform A | 1 | 0 | 0 | 1 |
| Gamma-aminobutyric acid receptor subunit pi | 0 | 1 | 0 | 1 |
| Gamma-aminobutyric acid receptor subunit delta | 0 | 1 | 0 | 1 |
| Gamma-aminobutyric acid receptor subunit alpha-1 | 0 | 1 | 0 | 1 |
| Thyroid hormone receptor beta | 0 | 1 | 0 | 1 |
| Gamma-aminobutyric acid receptor subunit beta-1 | 0 | 1 | 0 | 1 |
| Gamma-aminobutyric acid receptor subunit gamma-2 | 0 | 1 | 0 | 1 |
| Gamma-aminobutyric acid receptor subunit beta-3 | 0 | 1 | 0 | 1 |
| Adenosine receptor A1 | 0 | 2 | 0 | 2 |
| Gamma-aminobutyric acid receptor subunit alpha-5 | 0 | 1 | 0 | 1 |
| Gamma-aminobutyric acid receptor subunit alpha-3 | 0 | 1 | 0 | 1 |
| Gamma-aminobutyric acid receptor subunit alpha-2 | 0 | 1 | 0 | 1 |
| Gamma-aminobutyric acid receptor subunit beta-2 | 0 | 1 | 0 | 1 |
| Gamma-aminobutyric acid receptor subunit alpha-4 | 0 | 1 | 0 | 1 |
| Gamma-aminobutyric acid receptor subunit epsilon | 0 | 1 | 0 | 1 |
| Gamma-aminobutyric acid receptor subunit alpha-6 | 0 | 1 | 0 | 1 |
| Sigma non-opioid intracellular receptor 1 | 0 | 0 | 1 | 1 |
| Solute carrier organic anion transporter family member 4C1 | 0 | 0 | 0 | 1 |
| Gamma-aminobutyric acid receptor subunit gamma-1 | 0 | 1 | 0 | 1 |
| Solute carrier organic anion transporter family member 4A1 | 0 | 0 | 0 | 1 |
| Gamma-aminobutyric acid receptor subunit gamma-3 | 0 | 1 | 0 | 1 |
| Solute carrier organic anion transporter family member 1C1 | 0 | 1 | 0 | 1 |
| Gamma-aminobutyric acid receptor subunit theta | 0 | 1 | 0 | 1 |
| [prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023] |