Page last updated: 2024-09-27

Angiolymphoid Hyperplasia with Eosinophilia

Solitary or multiple benign cutaneous nodules comprised of immature and mature vascular structures intermingled with endothelial cells and a varied infiltrate of eosinophils, histiocytes, lymphocytes, and mast cells.

Synonyms(3)

Synonym
Pseudopyogenic Granuloma
Angiolymphoid Hyperplasia with Eosinophilia
Granuloma, Pseudopyogenic

Research Excerpts

Overview

ExcerptReference
"Angiolymphoid hyperplasia with eosinophilia is an uncommon benign vascular proliferative lesion of unknown cause."( Bhatt, S; Cheney, ML; Googe, P; Hibberd, PL, 1993)
"Angiolymphoid hyperplasia with eosinophilia is a rare benign vascular lesion most commonly affecting the head and neck region."( Anjum, K; Dunnill, G; Fasanmade, A; Hughes, C; Thomas, S, 2010)
"Angiolymphoid hyperplasia with eosinophilia is a rare disease that can affect the ocular adnexal tissue."( Albert, DM; Azari, AA; Kanavi, MR; Lee, V; Lucarelli, M; Lundin, AM; Potter, HD, 2014)
"Angiolymphoid hyperplasia with eosinophilia is a rare, benign, vascular proliferation that presents as dome-shaped, light-pink-to-red-brown papules or subcutaneous masses that lack distinguishing surface changes."( Farhadian, JA; Meehan, SA; Shvartsbeyn, M; Urbanek, RW, 2015)
"Angiolymphoid hyperplasia with eosinophilia is a benign neoplasm that includes blood vessel proliferation and a dense eosinophilic inflammatory infiltrate."( Al-Soufi, L; Alshehabi, Z; Elshimali, Y; Hasan, AR; Youssef, A; Youssef, Y, 2018)
"Angiolymphoid hyperplasia with eosinophilia is an uncommon chronic inflammatory condition of unknown etiology."( Alfarhan, A; Alofi, MM; Alotaibi, HM; Maktabi, A, 2023)

Treatment

ExcerptReference
"Papular lesions of pseudopyogenic granuloma were examined before and during treatment with systemic corticosteroid using both light and electron microscopy."( Kimura, S, 1980)
"Painful paronychia and pseudopyogenic granuloma (PG) are common adverse drug reactions (ADRs) associated with the use of epidermal growth factor receptor tyrosine kinase inhibitors (EGFR-TKIs) to treat non-small cell lung cancer (NSCLC)."( Chen, CL; Chuang, CH; Liu, HL; Wei, PJ; Yang, CJ, 2023)

Research

Studies (193)

TimeframeStudies, This Condition (%)All Conditions %
pre-199017 (8.81)23.3326
1990's41 (21.24)12.5806
2000's56 (29.02)18.1394
2010's70 (36.27)28.8240
2020's9 (4.66)9.53
DrugIndicatedRelationship StrengthStudiesTrials
aminolevulinic acid0low10
choline0low10
salicylic acid0low220
creatine0low10
iodine0low10
nitrous oxide0low10
albendazole0low10
theophylline0low10
azathioprine0low20
cetirizine0low20
chlorambucil0low10
pentetic acid0low10
furosemide0low10
hydroxyurea0low10
indomethacin0low20
iohexol0low10
iopromide0low10
isoflurane0low10
khellin0low20
leflunomide0low20
loratadine0low10
pentoxifylline0low20
ono 10780low10
propranolol0low30
thalidomide0low30
prednisolone0low310
prednisone0low270
triamcinolone acetonide0low20
methylprednisolone0low40
framycetin0low10
isoxazoles0low20
dexamethasone 21-phosphate0low10
betamethasone0low10
methylprednisolone hemisuccinate0low10
technetium0low10
gadolinium0low10
silver nitrate0low10
triamcinolone0low30
timolol0low40
propiconazole0low60
imiquimod0low30
temoporfin0low10
capecitabine0low10
fluorodeoxyglucose f180low50
suplatast tosilate0low30
nicotine0low10
fibrinogen0low10
diprofos0low10
methotrexate0low10
puromycin0low10
inositol 3-phosphate0low10
tretinoin0low20
tacrolimus0low90
mycophenolic acid0low20
methylproamine0low10
bromochloroacetic acid0low10
polidocanol0low30
indomethacin farnesil0low10
etretinate0low10
isotretinoin0low10
phenylephrine hydrochloride0low10
acitretin0low10
clobetasol0low10
aluminum0low10
gadolinium dtpa0low10
jaw0low10
(9R)-9-chloro-11,17-dihydroxy-17-(2-hydroxy-1-oxoethyl)-10,13,16-trimethyl-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-3-one0low10
warfarin0low10
cyclosporine0low190
exudates0low10
eye0low10
concanavalin a0low10
phosphorus radioisotopes0low10

Protein Targets (792)

ProteinPotency MeasurementsInhibition MeasurementsActivation MeasurementsDrugs
IDH1110011
chromobox protein homolog 1120012
geminin270027
Chain A, JmjC domain-containing histone demethylation protein 3A1001
Luciferase120012
USP1 protein, partial120012
TDP1 protein290029
Microtubule-associated protein tau9009
AR protein320032
aldehyde dehydrogenase 1 family, member A1140014
glucocorticoid receptor [Homo sapiens]250025
estrogen nuclear receptor alpha370037
peroxisome proliferator activated receptor gamma190019
euchromatic histone-lysine N-methyltransferase 2220022
cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a210021
vitamin D3 receptor isoform VDRA100010
thyroid hormone receptor beta isoform 2220022
flap endonuclease 13003
serine/threonine-protein kinase PLK12002
eyes absent homolog 2 isoform a1001
DNA polymerase eta isoform 13003
peripheral myelin protein 22170017
survival motor neuron protein isoform d120012
histone acetyltransferase KAT2A isoform 17007
ATP-binding cassette sub-family C member 3026026
Multidrug resistance-associated protein 4026027
Bile salt export pump0707
Bile salt export pump030030
Rap guanine nucleotide exchange factor 31001
Cellular tumor antigen p53260026
Rap guanine nucleotide exchange factor 42002
Chain A, Beta-lactamase7007
glp-1 receptor, partial8008
hypoxia-inducible factor 1 alpha subunit160016
RAR-related orphan receptor gamma290029
ATAD5 protein, partial110011
Fumarate hydratase7007
GLI family zinc finger 3240024
caspase 7, apoptosis-related cysteine protease4004
nuclear receptor subfamily 1, group I, member 3190019
progesterone receptor180018
retinoic acid nuclear receptor alpha variant 1210021
retinoid X nuclear receptor alpha210021
estrogen-related nuclear receptor alpha250025
farnesoid X nuclear receptor180018
pregnane X nuclear receptor230023
polyprotein7007
67.9K protein5005
vitamin D (1,25- dihydroxyvitamin D3) receptor180018
caspase-34004
aryl hydrocarbon receptor190019
v-jun sarcoma virus 17 oncogene homolog (avian)100010
nuclear receptor subfamily 1, group I, member 27007
Histone H2A.x8008
cellular tumor antigen p53 isoform a5005
15-hydroxyprostaglandin dehydrogenase [NAD(+)] isoform 15005
nuclear factor erythroid 2-related factor 2 isoform 2110011
transcriptional regulator ERG isoform 33003
histone deacetylase 9 isoform 34004
heat shock protein beta-1130013
mitogen-activated protein kinase 13003
urokinase-type plasminogen activator precursor6006
plasminogen precursor6006
urokinase plasminogen activator surface receptor precursor6006
Vif0001
muscleblind-like protein 1 isoform 16006
DNA dC->dU-editing enzyme APOBEC-3G isoform 11001
lamin isoform A-delta10160016
neuropeptide S receptor isoform A4004
Voltage-dependent calcium channel gamma-2 subunit160016
Interferon beta180018
Integrin beta-34004
Integrin alpha-IIb4004
Methionine aminopeptidase0101
Glutamate receptor 2161017
Fatty-acid amide hydrolase 10101
Inositol monophosphatase 16006
Canalicular multispecific organic anion transporter 1025025
ATPase family AAA domain-containing protein 5170017
Ataxin-2180018
bromodomain adjacent to zinc finger domain 2B7007
Gamma-aminobutyric acid receptor subunit rho-10101
Glutamate receptor 10101
Glutamate receptor 20101
Glutamate receptor 30101
Glutamate receptor ionotropic, kainate 30101
Solute carrier family 15 member 10101
Glutamate receptor 40101
Solute carrier family 15 member 10101
Solute carrier family 15 member 20101
Chain A, MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASE6006
Chain A, TYROSYL-DNA PHOSPHODIESTERASE5005
Chain A, Ferritin light chain6006
interleukin 84004
acetylcholinesterase9009
thioredoxin reductase160016
phosphopantetheinyl transferase7007
SMAD family member 2100010
SMAD family member 3100010
thioredoxin glutathione reductase5005
EWS/FLI fusion protein130013
G140014
P532002
peroxisome proliferator-activated receptor delta140014
arylsulfatase A110011
thyroid stimulating hormone receptor8008
activating transcription factor 6120012
Bloom syndrome protein isoform 1120012
peripheral myelin protein 22 isoform 1100010
hemoglobin subunit beta1001
nuclear factor erythroid 2-related factor 2 isoform 1260026
DNA polymerase iota isoform a (long)7007
cytochrome P450 3A4 isoform 19009
M-phase phosphoprotein 86006
muscarinic acetylcholine receptor M17007
Gamma-aminobutyric acid receptor subunit pi91212
HLA class I histocompatibility antigen, B alpha chain 140014
Gamma-aminobutyric acid receptor subunit beta-191212
Gamma-aminobutyric acid receptor subunit delta91212
Gamma-aminobutyric acid receptor subunit gamma-291212
Gamma-aminobutyric acid receptor subunit alpha-591212
Gamma-aminobutyric acid receptor subunit alpha-391212
Gamma-aminobutyric acid receptor subunit gamma-191212
Gamma-aminobutyric acid receptor subunit alpha-291212
Gamma-aminobutyric acid receptor subunit alpha-491212
Gamma-aminobutyric acid receptor subunit gamma-391212
Gamma-aminobutyric acid receptor subunit alpha-691212
Nuclear receptor ROR-gamma7119
Gamma-aminobutyric acid receptor subunit alpha-191212
Gamma-aminobutyric acid receptor subunit beta-391212
Gamma-aminobutyric acid receptor subunit beta-291212
GABA theta subunit91212
Inositol hexakisphosphate kinase 1140014
Gamma-aminobutyric acid receptor subunit epsilon91212
Protein-arginine deiminase type-40303
cytochrome P450 2C9, partial140014
pregnane X receptor4004
cytochrome P450 family 3 subfamily A polypeptide 4170017
thyroid hormone receptor beta isoform a9009
galanin receptor type 30101
Glucocorticoid receptor012219
Glycine receptor subunit alpha-1012012
Glycine receptor subunit beta012012
Glycine receptor subunit alpha-2012012
Glycine receptor subunit alpha-3012012
ORF730011
Liver carboxylesterase 10001
atrial natriuretic peptide receptor 2 precursor1001
Histamine H1 receptor0314
Angiopoietin-1 receptor0011
Potassium voltage-gated channel subfamily H member 20606
Multidrug and toxin extrusion protein 10303
Histamine H4 receptor0202
ATP-dependent phosphofructokinase100010
NFKB1 protein, partial5005
GALC protein4004
GLS protein5005
Thrombopoietin3003
hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)100010
thyroid stimulating hormone receptor5005
potassium voltage-gated channel subfamily H member 2 isoform d5005
FAD-linked sulfhydryl oxidase ALR0001
Carbonic anhydrase 120304
Carbonic anhydrase 10405
Carbonic anhydrase 20518
Cytochrome P450 2D60415
Spike glycoprotein110011
Carbonic anhydrase 90406
Solute carrier organic anion transporter family member 1B30405
Chain A, Acetylcholinesterase0011
Chain A, Acetylcholinesterase0011
Chain A, Acetylcholinesterase0011
Chain A, Acetylcholinesterase0011
Chain A, Acetylcholinesterase0011
Chain A, Acetylcholinesterase0011
Chain A, Acetylcholinesterase0011
Chain A, Putative Glycine Betaine-binding Abc Transporter Protein0011
Chain A, PUTATIVE GLYCINE BETAINE-BINDING ABC TRANSPORTER PROTEIN0011
Chain A, Glycine betaine/carnitine/choline-binding protein0011
Chain A, Glycine betaine/carnitine/choline-binding protein0011
Chain A, Glycine betaine/carnitine/choline-binding protein0011
Chain A, Glycine betaine/carnitine/choline-binding protein0011
Chain A, Choline-binding protein0011
Solute carrier family 22 member 10102
Solute carrier family 22 member 20001
Solute carrier family 22 member 1 0103
Solute carrier family 22 member 20101
Neuronal acetylcholine receptor subunit alpha-30326
Neuronal acetylcholine receptor subunit alpha-41428
Neuronal acetylcholine receptor subunit alpha-20326
Neuronal acetylcholine receptor subunit beta-21428
Neuronal acetylcholine receptor subunit beta-30326
Neuronal acetylcholine receptor subunit beta-40326
Neuronal acetylcholine receptor subunit alpha-50326
Acetylcholinesterase0303
Sodium- and chloride-dependent creatine transporter 10101
Choline O-acetyltransferase 0001
Neuronal acetylcholine receptor subunit alpha-60326
Neuronal acetylcholine receptor subunit alpha-90326
Neuronal acetylcholine receptor subunit alpha-70326
Solute carrier family 22 member 10203
High affinity choline transporter 10101
Neuronal acetylcholine receptor subunit alpha-100326
Solute carrier family 22 member 20203
Sodium- and chloride-dependent creatine transporter 10101
Proton-coupled amino acid transporter 10101
estrogen receptor 2 (ER beta)130013
cytochrome P450 2D6130013
nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105), isoform CRA_a110011
Menin0011
Lecithin retinol acyltransferase0101
30S ribosomal protein S60203
30S ribosomal protein S70203
50S ribosomal protein L150203
50S ribosomal protein L100203
50S ribosomal protein L110203
50S ribosomal protein L7/L120203
50S ribosomal protein L190203
50S ribosomal protein L10203
50S ribosomal protein L200203
50S ribosomal protein L270203
50S ribosomal protein L280203
50S ribosomal protein L290203
50S ribosomal protein L310203
50S ribosomal protein L31 type B0203
50S ribosomal protein L320203
50S ribosomal protein L330203
50S ribosomal protein L340203
50S ribosomal protein L350203
50S ribosomal protein L360203
30S ribosomal protein S100203
30S ribosomal protein S110203
30S ribosomal protein S120203
30S ribosomal protein S130203
30S ribosomal protein S160203
30S ribosomal protein S180203
30S ribosomal protein S190203
30S ribosomal protein S200203
30S ribosomal protein S20203
30S ribosomal protein S30203
30S ribosomal protein S40203
30S ribosomal protein S50203
30S ribosomal protein S80203
30S ribosomal protein S90203
50S ribosomal protein L130203
50S ribosomal protein L140203
50S ribosomal protein L160203
50S ribosomal protein L230203
30S ribosomal protein S150203
50S ribosomal protein L170203
50S ribosomal protein L210203
50S ribosomal protein L300203
50S ribosomal protein L60203
30S ribosomal protein S140203
30S ribosomal protein S170203
30S ribosomal protein S10203
50S ribosomal protein L180203
Lethal factor0101
50S ribosomal protein L20203
50S ribosomal protein L30203
50S ribosomal protein L240203
50S ribosomal protein L40203
50S ribosomal protein L220203
50S ribosomal protein L50203
30S ribosomal protein S210203
50S ribosomal protein L250203
50S ribosomal protein L36 20203
Protein Rev 0011
Aminoglycoside 3'-phosphotransferase 0001
Tyrosyl-DNA phosphodiesterase 10202
thyrotropin-releasing hormone receptor2002
Solute carrier family 22 member 60303
Albumin0336
Carbonic anhydrase 30202
Glucose-6-phosphate 1-dehydrogenase0202
Cytochrome P450 2C9 0617
Carbonic anhydrase 40304
Carbonic anhydrase 60203
Serum paraoxonase/arylesterase 10202
Corticosteroid 11-beta-dehydrogenase isozyme 10101
Carbonic anhydrase 5A, mitochondrial0304
Carbonic anhydrase 70203
Adenosine receptor A10202
Corticosteroid 11-beta-dehydrogenase isozyme 10101
Cytochrome P450 2J20404
6-phosphogluconate dehydrogenase, decarboxylating0202
Holo-[acyl-carrier-protein] synthase0101
Solute carrier organic anion transporter family member 2A10101
Sodium/bile acid cotransporter0202
Carbonic anhydrase 130203
G-protein coupled receptor 350112
CDGSH iron-sulfur domain-containing protein 10202
Carbonic anhydrase 140203
Broad substrate specificity ATP-binding cassette transporter ABCG20203
Carbonic anhydrase 5B, mitochondrial0203
Gamma-aminobutyric acid receptor subunit pi0101
Gamma-aminobutyric acid receptor subunit delta0101
Stromelysin-10022
Gamma-aminobutyric acid receptor subunit alpha-10101
Urease subunit alpha0101
Gamma-aminobutyric acid receptor subunit beta-10101
Gamma-aminobutyric acid receptor subunit gamma-20101
Ribonucleoside-diphosphate reductase large subunit0101
Gamma-aminobutyric acid receptor subunit beta-30101
Gamma-aminobutyric acid receptor subunit alpha-50101
Gamma-aminobutyric acid receptor subunit alpha-30101
Gamma-aminobutyric acid receptor subunit alpha-20101
Gamma-aminobutyric acid receptor subunit beta-20101
Gamma-aminobutyric acid receptor subunit alpha-40101
Urease subunit beta0101
Gamma-aminobutyric acid receptor subunit epsilon0101
Gamma-aminobutyric acid receptor subunit alpha-60101
Gamma-aminobutyric acid receptor subunit gamma-10101
Gamma-aminobutyric acid receptor subunit gamma-30101
Gamma-aminobutyric acid receptor subunit theta0101
DNA polymerase beta2002
Histamine H2 receptor0202
Alpha-1D adrenergic receptor0214
Adenosine receptor A2a0539
7,8-dihydro-8-oxoguanine triphosphatase0101
Toll-like receptor 80011
Toll-like receptor 70011
Chain A, membrane-associated prostaglandin E synthase-20101
Chain A, Putative fructose-1,6-bisphosphate aldolase3003
Chain A, 2-oxoglutarate Oxygenase8008
Chain A, Cruzipain4004
glucocerebrosidase1001
Parkin4004
heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)2002
cytochrome P450 2D6 isoform 14004
cytochrome P450 2C9 precursor3003
ras-related protein Rab-9A3003
serine/threonine-protein kinase mTOR isoform 13003
nuclear receptor ROR-gamma isoform 19009
DNA polymerase kappa isoform 14004
Prostaglandin-H2 D-isomerase0101
Prostaglandin E synthase0101
Prostaglandin G/H synthase 1 0102
Prostaglandin G/H synthase 2 0102
3',5'-cyclic-AMP phosphodiesterase 0101
Solute carrier organic anion transporter family member 2B1 0202
Cytochrome c oxidase subunit 20101
Epidermal growth factor receptor0101
Phospholipase A2, major isoenzyme0101
Prostaglandin G/H synthase 10304
Procathepsin L0101
ATP-dependent translocase ABCB10404
Interleukin-80101
Androgen receptor0213
Polyunsaturated fatty acid 5-lipoxygenase0102
Aldo-keto reductase family 1 member B10202
Aldo-keto reductase family 1 member B10101
Aldo-keto reductase family 1 member C40101
Prostaglandin G/H synthase 10101
Prostaglandin G/H synthase 10202
Sodium-dependent dopamine transporter0101
Sodium- and chloride-dependent GABA transporter 10101
Thromboxane-A synthase 0101
Adenosine receptor A10304
Indoleamine 2,3-dioxygenase 10202
Caspase-10001
Nitric oxide synthase, inducible0101
Adenosine receptor A2a0204
Substance-P receptor0101
Prostaglandin E2 receptor EP3 subtype0101
Sodium- and chloride-dependent GABA transporter 20101
Sodium- and chloride-dependent GABA transporter 30101
Prostaglandin E2 receptor EP4 subtype0101
Multidrug resistance-associated protein 1 0102
Bifunctional epoxide hydrolase 20101
Prostaglandin G/H synthase 20415
Prostaglandin G/H synthase 2 0101
Prostaglandin E2 receptor EP1 subtype0101
Peroxisome proliferator-activated receptor gamma0022
Aldo-keto reductase family 1 member C30202
Histamine H2 receptor5005
Sodium- and chloride-dependent betaine transporter0101
C-X-C chemokine receptor type 30101
Aldo-keto reductase family 1 member C2 0101
Guanine nucleotide-binding protein G4004
Prostaglandin D2 receptor 0202
Solute carrier organic anion transporter family member 1A30102
Prostaglandin G/H synthase 20303
Lactoylglutathione lyase0101
Aldo-keto reductase family 1 member C10101
Prostaglandin G/H synthase 20102
Uracil nucleotide/cysteinyl leukotriene receptor0202
Solute carrier family 22 member 60203
Solute carrier family 22 member 70002
Sigma intracellular receptor 20101
Prostaglandin E2 receptor EP2 subtype0101
Rho-associated protein kinase 20101
Prostaglandin G/H synthase 1 0101
Nicotinate phosphoribosyltransferase0202
Solute carrier family 22 member 80203
Dehydrogenase/reductase SDR family member 90101
P2Y purinoceptor 120101
Cytosolic phospholipase A2 gamma0101
Prostaglandin D2 receptor 20112
Solute carrier organic anion transporter family member 1B10303
importin subunit beta-1 isoform 13003
snurportin-13003
GTP-binding nuclear protein Ran isoform 12002
Neuronal acetylcholine receptor subunit beta-20314
Neuronal acetylcholine receptor subunit alpha-70325
regulator of G-protein signaling 45005
Caspase-72002
parathyroid hormone/parathyroid hormone-related peptide receptor precursor2002
caspase-32002
peptidyl-prolyl cis-trans isomerase NIMA-interacting 13003
Ornithine decarboxylase0002
Adenosine receptor A30617
Retinoic acid receptor alpha0224
Alpha-1B adrenergic receptor0516
Alpha-2B adrenergic receptor0214
Retinoic acid receptor gamma0224
Retinoic acid receptor beta0224
Cellular retinoic acid-binding protein 20022
Mitogen-activated protein kinase 10202
Retinoic acid receptor RXR-alpha0224
Retinoic acid receptor RXR-beta0224
Retinoic acid receptor RXR-gamma0224
Cellular retinoic acid-binding protein 10203
5-hydroxytryptamine receptor 2B0819
Alpha-1A adrenergic receptor0516
Cellular retinoic acid-binding protein 10022
Mitogen-activated protein kinase 140101
Olfactory receptor 51E20101
Chymotrypsinogen A0101
cytochrome P450 2C19 precursor4004
Cytochrome P450 1A10202
Cytochrome P450 1A20516
Cytochrome P450 3A40516
Cytochrome P450 2C190314
Cytochrome P450 1B10101
matrix metalloproteinase 1, partial0011
PPM1D protein3003
nonstructural protein 16006
pyruvate kinase1001
NPC intracellular cholesterol transporter 1 precursor2002
huntingtin isoform 22002
Dihydroorotate dehydrogenase (quinone), mitochondrial0101
Aldo-keto reductase family 1 member B10202
Amine oxidase [flavin-containing] A0101
Endothelin receptor type B1001
Sodium-dependent noradrenaline transporter 0202
Endothelin-1 receptor1001
Sodium-dependent dopamine transporter 0202
Dihydroorotate dehydrogenase (quinone), mitochondrial0101
Dihydroorotate dehydrogenase (quinone), mitochondrial0101
15-lipoxygenase, partial3003
isocitrate dehydrogenase 1, partial1001
alpha-galactosidase2002
ubiquitin carboxyl-terminal hydrolase 2 isoform a2002
Polyunsaturated fatty acid lipoxygenase ALOX15B3003
Voltage-dependent L-type calcium channel subunit alpha-1F0101
Nuclear receptor subfamily 1 group I member 20033
Angiotensin-converting enzyme0202
Platelet-activating factor receptor0101
Disintegrin and metalloproteinase domain-containing protein 172002
Voltage-dependent L-type calcium channel subunit alpha-1D 0101
Voltage-dependent L-type calcium channel subunit alpha-1S0101
Voltage-dependent L-type calcium channel subunit alpha-1C0202
Nuclear receptor subfamily 3 group C member 3 0202
Bile acid receptor0112
Sodium-dependent neutral amino acid transporter B(0)AT20101
Potassium channel subfamily K member 90101
Chain B, DIHYDROFOLATE REDUCTASE0011
Chain B, DIHYDROFOLATE REDUCTASE0011
Chain B, DIHYDROFOLATE REDUCTASE0011
Chain A, HADH2 protein5005
Chain B, HADH2 protein5005
acid sphingomyelinase1001
dopamine D1 receptor2002
ClpP1001
Thymidylate synthase 0101
Thymidylate synthase 0101
polyunsaturated fatty acid lipoxygenase ALOX121001
nuclear receptor coactivator 1 isoform 1 [Homo sapiens]0101
transactivating tegument protein VP16 [Human herpesvirus 1]0101
caspase-1 isoform alpha precursor1001
nuclear receptor coactivator 3 isoform a0101
Toll-like receptor 40101
Fatty-acid amide hydrolase 10101
ATP-binding cassette sub-family C member 30102
Dihydrofolate reductase0203
Dihydrofolate reductase0203
Dihydrofolate reductase 0101
Dihydrofolate reductase0101
Dihydrofolate reductase0101
Dihydrofolate reductase0203
Thymidylate synthase0101
Tyrosine-protein kinase ABL10011
Thymidylate synthase0202
Bifunctional dihydrofolate reductase-thymidylate synthase0101
Thymidylate synthase0202
5-hydroxytryptamine receptor 2C0102
High mobility group protein B10022
Dihydrofolate reductase0101
Thymidylate synthase0101
Dihydrofolate reductase0224
Bifunctional dihydrofolate reductase-thymidylate synthase0101
Folate receptor beta0101
5-hydroxytryptamine receptor 2A0101
Cytochrome P450 11B1, mitochondrial 0101
Folate receptor alpha0101
Dihydrofolate reductase0202
Histidine decarboxylase0101
Trifunctional purine biosynthetic protein adenosine-30101
Cyclin-dependent kinase 20011
Bifunctional purine biosynthesis protein ATIC0202
Delta-type opioid receptor0202
Mu-type opioid receptor0202
Kappa-type opioid receptor0101
Reduced folate transporter0202
Folylpolyglutamate synthase, mitochondrial0103
Caspase-71001
Dihydrofolate reductase0101
Pteridine reductase 10101
Folylpolyglutamate synthase, mitochondrial0103
Bifunctional dihydrofolate reductase-thymidylate synthase0101
TAR DNA-binding protein 436006
Bifunctional dihydrofolate reductase-thymidylate synthase0101
Canalicular multispecific organic anion transporter 10203
Trifunctional purine biosynthetic protein adenosine-30101
Solute carrier family 22 member 200202
Dihydrofolate reductase 0101
Solute carrier family 22 member 60202
Dihydrofolate reductase0101
ATP-binding cassette sub-family C member 110001
Proton-coupled folate transporter0101
Multidrug resistance associated protein0102
Solute carrier family 22 member 110001
Androgen receptor0303
Nuclear receptor subfamily 1 group I member 20011
Chain A, Inosine-5'-Monophosphate Dehydrogenase 20101
lethal factor (plasmid)2002
UDP-glucuronosyltransferase 1A90001
Inosine-5'-monophosphate dehydrogenase 20202
Glutamate receptor 10101
Glutamate receptor 30101
Glutamate receptor 40101
Inosine-5'-monophosphate dehydrogenase 1 0202
UDP-glucuronosyltransferase 1A1 0001
Sodium-dependent serotonin transporter0101
Alpha-synuclein1102
Inosine-5'-monophosphate dehydrogenase0102
UDP-glucuronosyltransferase 1A70001
UDP-glucuronosyltransferase 1A100001
UDP-glucuronosyltransferase 1A80001
5-hydroxytryptamine receptor 3E0101
Smad32002
D(1A) dopamine receptor2002
Neuronal acetylcholine receptor subunit alpha-40213
Transient receptor potential cation channel subfamily A member 10011
5-hydroxytryptamine receptor 3B0101
Acetylcholine receptor subunit alpha0213
Acetylcholine receptor subunit alpha0213
Acetylcholine receptor subunit beta0213
Acetylcholine receptor subunit gamma0213
Acetylcholine receptor subunit delta0213
Acetylcholine receptor subunit gamma0213
Muscarinic acetylcholine receptor M10101
Muscarinic acetylcholine receptor M30101
Muscarinic acetylcholine receptor M40202
Muscarinic acetylcholine receptor M50101
Neuronal acetylcholine receptor subunit alpha-40101
Muscarinic acetylcholine receptor M20101
Acetylcholine receptor subunit beta0213
Cytochrome P450 2A60213
Translocator protein0101
Cytochrome P450 2A50101
Acetylcholine receptor subunit beta-like 20202
Neuronal acetylcholine receptor subunit alpha-50011
Neuronal acetylcholine receptor subunit beta-40213
Muscarinic acetylcholine receptor M40101
Neuronal acetylcholine receptor subunit alpha-30213
Delta-type opioid receptor0101
Neuronal acetylcholine receptor subunit alpha-40213
5-hydroxytryptamine receptor 3A0101
Neuronal acetylcholine receptor subunit alpha-70202
Acetylcholine-binding protein0112
Mu-type opioid receptor0101
Acetylcholine receptor subunit epsilon0011
Neuronal acetylcholine receptor subunit beta-30112
Acetylcholine receptor subunit delta0213
Neuronal acetylcholine receptor subunit alpha-20101
Neuronal acetylcholine receptor subunit alpha-60112
Cytochrome P450 2A130112
Neuronal acetylcholine receptor subunit alpha-50202
Liver carboxylesterase B-10101
5-hydroxytryptamine receptor 3D0101
Transient receptor potential cation channel subfamily A member 10011
Neuronal acetylcholine receptor subunit beta-30202
Neuronal acetylcholine receptor subunit beta-40202
Neuronal acetylcholine receptor subunit alpha-30202
Soluble acetylcholine receptor0101
5-hydroxytryptamine receptor 3C0101
Neuronal acetylcholine receptor subunit alpha-20202
Neuronal acetylcholine receptor subunit beta-20213
Neuronal acetylcholine receptor subunit alpha-60202
Integrin beta0011
Glycoprotein IIb0011
Transporter0113
Cruzipain0101
Cysteinyl leukotriene receptor 10101
Cysteinyl leukotriene receptor 20101
Cysteinyl leukotriene receptor 10101
endonuclease IV2002
vasopressin V1b receptor1001
relaxin receptor 1 isoform 11001
cGMP-dependent 3',5'-cyclic phosphodiesterase0202
High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8A0101
cGMP-specific 3',5'-cyclic phosphodiesterase0101
Tumor necrosis factor0101
Cholinesterase0101
cAMP-specific 3',5'-cyclic phosphodiesterase 4A0404
Adenosine receptor A2b0203
cAMP-specific 3',5'-cyclic phosphodiesterase 4B0404
cAMP-specific 3',5'-cyclic phosphodiesterase 4D0404
Chitotriosidase-10314
cGMP-inhibited 3',5'-cyclic phosphodiesterase A0202
Endochitinase B10314
beta-2 adrenergic receptor1001
lysosomal alpha-glucosidase preproprotein1001
mu-type opioid receptor isoform MOR-10011
Vpr1001
5-hydroxytryptamine receptor 2A0011
luciferase0001
Fatty acid-binding protein, liver0101
Estrogen receptor0202
Progesterone receptor0203
Glucocorticoid receptor0112
Glucocorticoid receptor0011
Corticosteroid-binding globulin0101
Mineralocorticoid receptor 0213
Glutamine synthetase0011
Histamine H1 receptor0011
Nociceptin receptor0011
Estrogen receptor beta0202
heat shock protein HSP 90-alpha isoform 20001
heat shock protein 90, putative0001
Beta-1 adrenergic receptor 0124
Voltage-dependent L-type calcium channel subunit alpha-1C0101
5-hydroxytryptamine receptor 40202
Beta-2 adrenergic receptor0415
Muscarinic acetylcholine receptor M20112
Beta-1 adrenergic receptor0415
5-hydroxytryptamine receptor 1A0202
Alpha-2A adrenergic receptor0124
Beta-2 adrenergic receptor0203
Cytochrome P450 2C80101
Muscarinic acetylcholine receptor M10112
Beta-3 adrenergic receptor0415
D(2) dopamine receptor0112
Beta-1 adrenergic receptor0315
Alpha-2C adrenergic receptor0124
D(3) dopamine receptor0202
5-hydroxytryptamine receptor 1A0528
Alpha-2B adrenergic receptor0011
Muscarinic acetylcholine receptor M30112
D(1A) dopamine receptor0112
Voltage-dependent L-type calcium channel subunit alpha-1C0101
Alpha-2C adrenergic receptor0011
Alpha-2A adrenergic receptor0011
Alpha-1D adrenergic receptor0213
Endothelin-1 receptor0112
Beta-3 adrenergic receptor0202
5-hydroxytryptamine receptor 1B0213
5-hydroxytryptamine receptor 2A0213
5-hydroxytryptamine receptor 2C0213
5-hydroxytryptamine receptor 1B0404
Neuromedin-K receptor0011
Type-1 angiotensin II receptor0112
Sodium-dependent serotonin transporter0202
Cholecystokinin receptor type A0112
5-hydroxytryptamine receptor 70112
Beta-1 adrenergic receptor0101
Alpha-1A adrenergic receptor0124
Alpha-1B adrenergic receptor0012
Mu-type opioid receptor0112
Vasopressin V1a receptor0112
Delta-type opioid receptor0112
Kappa-type opioid receptor0112
5-hydroxytryptamine receptor 60213
5-hydroxytryptamine receptor 70101
Beta-2 adrenergic receptor0101
Sodium channel protein type 5 subunit alpha0101
Beta-2 adrenergic receptor0124
Sigma non-opioid intracellular receptor 10202
Nuclear receptor subfamily 2 group E member 10022
Aminopeptidase N0101
Aminopeptidase N0101
Puromycin-sensitive aminopeptidase0101
chaperonin-containing TCP-1 beta subunit homolog1001
Estrogen receptor beta0001
Inhibitor of nuclear factor kappa-B kinase subunit beta0001
Polyphenol oxidase 20102
5'-AMP-activated protein kinase subunit beta-20001
Polymerase acidic protein0011
Tyrosine-protein phosphatase YopH0101
Prolyl 4-hydroxylase subunit alpha-10101
Tyrosine-protein phosphatase non-receptor type 10103
Estrogen receptor0001
Cystathionine gamma-lyase0101
5'-AMP-activated protein kinase subunit gamma-10001
5'-AMP-activated protein kinase catalytic subunit alpha-20001
Xanthine dehydrogenase/oxidase0101
5'-AMP-activated protein kinase catalytic subunit alpha-10001
Carbonic anhydrase0101
Ubiquitin-like domain-containing CTD phosphatase 10101
Carbonic anhydrase 150101
5'-AMP-activated protein kinase subunit gamma-30001
5'-AMP-activated protein kinase subunit gamma-20001
5'-AMP-activated protein kinase subunit beta-10001
UDP-glucuronosyltransferase 2B70001
Cytochrome P450 3A50101
UDP-glucuronosyltransferase 1A40001
Serine/threonine-protein kinase mTOR0101
Peptidyl-prolyl cis-trans isomerase FKBP1A0213
Peptidyl-prolyl cis-trans isomerase FKBP1B0011
Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform0101
Peptidyl-prolyl cis-trans isomerase FKBP50101
Splicing factor 3B subunit 30101
Cereblon isoform 40202
cAMP-specific 3',5'-cyclic phosphodiesterase 4C0303
DNA-binding protein Ikaros0001
DNA damage-binding protein 10112
Protein cereblon0214
Chain A, Pyridoxal kinase0101
Chain A, Pyridoxal Kinase0101
Phosphodiesterase 0202
Potassium channel subfamily K member 20011
Renin0101
Alkaline phosphatase, tissue-nonspecific isozyme0202
Intestinal-type alkaline phosphatase0101
Replicase polyprotein 1ab0101
Replicase polyprotein 1ab0101
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A 0101
cAMP-specific 3',5'-cyclic phosphodiesterase 4D 0101
cAMP-specific 3',5'-cyclic phosphodiesterase 4C0101
cAMP-specific 3',5'-cyclic phosphodiesterase 4B0101
Thyroid hormone receptor beta0101
Adenosine receptor A10202
Adenosine receptor A30101
Adenosine receptor A2b0102
Adenosine receptor A10215
Vasopressin V2 receptor0001
Adenosine receptor A2a0101
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform 0101
Adenosine receptor A10101
cAMP-specific 3',5'-cyclic phosphodiesterase 4A0101
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A0101
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B0101
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B0101
Adenylate cyclase type 10001
cGMP-inhibited 3',5'-cyclic phosphodiesterase B0101
High affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A0101
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C0101
Sigma non-opioid intracellular receptor 10101
Adenosine receptor A2b0001
Palmitoleoyl-protein carboxylesterase NOTUM0011
Phospholipase A-2-activating protein0101
Chain A, Nuclear Receptor ROR-beta0101
Chain A, ATP-DEPENDENT DNA HELICASE Q11001
Amyloid-beta precursor protein0101
Ornithine decarboxylase0001
60 kDa chaperonin0101
Retinoic acid receptor alpha0227
60 kDa heat shock protein, mitochondrial0101
Retinoic acid receptor beta0227
Retinoic acid receptor gamma 0227
Alpha-1A adrenergic receptor0101
Retinoic acid receptor RXR-alpha0224
Retinoic acid receptor RXR-beta0224
Nuclear receptor ROR-alpha0101
Retinoic acid receptor RXR-gamma0224
10 kDa heat shock protein, mitochondrial0101
Peptidyl-prolyl cis-trans isomerase NIMA-interacting 10213
Thiosulfate sulfurtransferase0101
60 kDa chaperonin 0101
10 kDa chaperonin 0101
Indoleamine 2,3-dioxygenase 20101
Nuclear receptor ROR-beta0101
procathepsin L isoform 1 preproprotein0101
Albumin0011
Proprotein convertase subtilisin/kexin type 70101
Vitamin K epoxide reductase complex subunit 1-like protein 10101
Vitamin K epoxide reductase complex subunit 10101
Protease 0101
Vitamin K epoxide reductase complex subunit 1-like protein 10101
Vitamin K epoxide reductase complex subunit 1 0202
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]