| Protein | Potency Measurements | Inhibition Measurements | Activation Measurements | Drugs |
|---|
| Chain A, MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASE | 2 | 0 | 0 | 2 |
| Chain E, LYSINE, ARGININE, ORNITHINE-BINDING PROTEIN | 0 | 0 | 1 | 1 |
| Chain E, LYSINE, ARGININE, ORNITHINE-BINDING PROTEIN | 0 | 0 | 1 | 1 |
| Chain E, LYSINE, ARGININE, ORNITHINE-BINDING PROTEIN | 0 | 0 | 1 | 1 |
| thioredoxin reductase | 1 | 0 | 0 | 1 |
| phosphopantetheinyl transferase | 1 | 0 | 0 | 1 |
| NFKB1 protein, partial | 2 | 0 | 0 | 2 |
| GLS protein | 3 | 0 | 0 | 3 |
| thyroid stimulating hormone receptor | 2 | 0 | 0 | 2 |
| alpha-galactosidase | 1 | 0 | 0 | 1 |
| euchromatic histone-lysine N-methyltransferase 2 | 3 | 0 | 0 | 3 |
| cytochrome P450 2C19 precursor | 2 | 0 | 0 | 2 |
| chromobox protein homolog 1 | 2 | 0 | 0 | 2 |
| flap endonuclease 1 | 2 | 0 | 0 | 2 |
| DNA polymerase iota isoform a (long) | 3 | 0 | 0 | 3 |
| muscarinic acetylcholine receptor M1 | 2 | 0 | 0 | 2 |
| lethal factor (plasmid) | 1 | 0 | 0 | 1 |
| Cytochrome P450 3A4 | 0 | 0 | 0 | 1 |
| Nitric oxide synthase, endothelial | 0 | 0 | 0 | 2 |
| Nitric oxide synthase, brain | 0 | 0 | 0 | 1 |
| Nitric oxide synthase, brain | 0 | 0 | 0 | 1 |
| Nitric oxide synthase, inducible | 0 | 0 | 0 | 1 |
| Nitric oxide synthase, inducible | 0 | 0 | 1 | 3 |
| Cationic amino acid transporter 3 | 0 | 2 | 0 | 2 |
| ATP-dependent phosphofructokinase | 4 | 0 | 0 | 4 |
| histone acetyltransferase KAT2A isoform 1 | 2 | 0 | 0 | 2 |
| Angiotensin-converting enzyme | 0 | 0 | 0 | 1 |
| B2 bradykinin receptor | 0 | 1 | 0 | 1 |
| B2 bradykinin receptor | 0 | 2 | 1 | 5 |
| B1 bradykinin receptor | 0 | 1 | 0 | 1 |
| Olfactory receptor 51E2 | 0 | 0 | 1 | 1 |
| arylsulfatase A | 2 | 0 | 0 | 2 |
| atrial natriuretic peptide receptor 1 precursor | 1 | 0 | 0 | 1 |
| atrial natriuretic peptide receptor 2 precursor | 2 | 0 | 0 | 2 |
| ATP-binding cassette sub-family C member 3 | 0 | 3 | 0 | 3 |
| Multidrug resistance-associated protein 4 | 0 | 3 | 0 | 3 |
| Bile salt export pump | 0 | 4 | 0 | 4 |
| Histamine H1 receptor | 0 | 4 | 0 | 4 |
| MBT domain-containing protein 1 | 0 | 1 | 0 | 1 |
| Potassium voltage-gated channel subfamily H member 2 | 0 | 1 | 0 | 1 |
| Solute carrier family 22 member 1 | 0 | 1 | 0 | 1 |
| Lethal(3)malignant brain tumor-like protein 4 | 0 | 1 | 0 | 1 |
| Canalicular multispecific organic anion transporter 1 | 0 | 3 | 0 | 3 |
| Lethal(3)malignant brain tumor-like protein 3 | 0 | 1 | 0 | 1 |
| Ataxin-2 | 2 | 0 | 0 | 2 |
| Chloroquine resistance transporter | 0 | 1 | 0 | 1 |
| Solute carrier family 22 member 2 | 0 | 1 | 0 | 1 |
| Lethal(3)malignant brain tumor-like protein 1 | 0 | 1 | 0 | 1 |
| glp-1 receptor, partial | 1 | 0 | 0 | 1 |
| pregnane X receptor | 2 | 0 | 0 | 2 |
| hypoxia-inducible factor 1 alpha subunit | 1 | 0 | 0 | 1 |
| RAR-related orphan receptor gamma | 3 | 0 | 0 | 3 |
| SMAD family member 2 | 2 | 0 | 0 | 2 |
| SMAD family member 3 | 2 | 0 | 0 | 2 |
| TDP1 protein | 2 | 0 | 0 | 2 |
| GLI family zinc finger 3 | 2 | 0 | 0 | 2 |
| AR protein | 3 | 0 | 0 | 3 |
| estrogen receptor 2 (ER beta) | 2 | 0 | 0 | 2 |
| nuclear receptor subfamily 1, group I, member 3 | 2 | 0 | 0 | 2 |
| progesterone receptor | 2 | 0 | 0 | 2 |
| cytochrome P450 family 3 subfamily A polypeptide 4 | 3 | 0 | 0 | 3 |
| glucocorticoid receptor [Homo sapiens] | 2 | 0 | 0 | 2 |
| retinoic acid nuclear receptor alpha variant 1 | 3 | 0 | 0 | 3 |
| retinoid X nuclear receptor alpha | 2 | 0 | 0 | 2 |
| estrogen-related nuclear receptor alpha | 2 | 0 | 0 | 2 |
| farnesoid X nuclear receptor | 2 | 0 | 0 | 2 |
| pregnane X nuclear receptor | 2 | 0 | 0 | 2 |
| estrogen nuclear receptor alpha | 3 | 0 | 0 | 3 |
| G | 2 | 0 | 0 | 2 |
| cytochrome P450 2D6 | 2 | 0 | 0 | 2 |
| peroxisome proliferator-activated receptor delta | 2 | 0 | 0 | 2 |
| peroxisome proliferator activated receptor gamma | 2 | 0 | 0 | 2 |
| vitamin D (1,25- dihydroxyvitamin D3) receptor | 2 | 0 | 0 | 2 |
| cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a | 2 | 0 | 0 | 2 |
| thyroid stimulating hormone receptor | 2 | 0 | 0 | 2 |
| v-jun sarcoma virus 17 oncogene homolog (avian) | 2 | 0 | 0 | 2 |
| nuclear receptor subfamily 1, group I, member 2 | 2 | 0 | 0 | 2 |
| Histone H2A.x | 1 | 0 | 0 | 1 |
| parathyroid hormone/parathyroid hormone-related peptide receptor precursor | 1 | 0 | 0 | 1 |
| thyroid hormone receptor beta isoform 2 | 2 | 0 | 0 | 2 |
| heat shock protein beta-1 | 1 | 0 | 0 | 1 |
| nuclear factor erythroid 2-related factor 2 isoform 1 | 2 | 0 | 0 | 2 |
| geminin | 2 | 0 | 0 | 2 |
| peripheral myelin protein 22 | 2 | 0 | 0 | 2 |
| Voltage-dependent calcium channel gamma-2 subunit | 2 | 0 | 0 | 2 |
| Rap guanine nucleotide exchange factor 3 | 1 | 0 | 0 | 1 |
| Interferon beta | 2 | 0 | 0 | 2 |
| HLA class I histocompatibility antigen, B alpha chain | 2 | 0 | 0 | 2 |
| Estrogen receptor | 0 | 3 | 1 | 4 |
| Glucocorticoid receptor | 0 | 4 | 1 | 5 |
| Sex hormone-binding globulin | 0 | 0 | 2 | 2 |
| Cellular tumor antigen p53 | 2 | 0 | 0 | 2 |
| Cytochrome P450 1A2 | 0 | 1 | 0 | 1 |
| Glycine receptor subunit alpha-1 | 0 | 4 | 0 | 4 |
| Aldo-keto reductase family 1 member B1 | 0 | 4 | 0 | 4 |
| Alpha-2A adrenergic receptor | 0 | 4 | 0 | 4 |
| Adenosine receptor A3 | 0 | 2 | 0 | 2 |
| Cytochrome P450 2C9 | 0 | 1 | 0 | 1 |
| Beta-3 adrenergic receptor | 0 | 2 | 0 | 2 |
| Androgen receptor | 0 | 4 | 0 | 4 |
| Alpha-1B adrenergic receptor | 0 | 2 | 0 | 2 |
| Alpha-2B adrenergic receptor | 0 | 4 | 0 | 4 |
| Alpha-2C adrenergic receptor | 0 | 2 | 0 | 2 |
| Glutamate receptor 2 | 2 | 0 | 0 | 2 |
| Muscarinic acetylcholine receptor M3 | 0 | 4 | 0 | 4 |
| Glycine receptor subunit beta | 0 | 4 | 0 | 4 |
| Substance-K receptor | 0 | 2 | 0 | 2 |
| D(1A) dopamine receptor | 0 | 2 | 0 | 2 |
| Glycine receptor subunit alpha-2 | 0 | 4 | 0 | 4 |
| Sodium-dependent noradrenaline transporter | 0 | 4 | 0 | 4 |
| Glycine receptor subunit alpha-3 | 0 | 4 | 0 | 4 |
| 5-hydroxytryptamine receptor 2A | 0 | 4 | 0 | 4 |
| Sodium-dependent serotonin transporter | 0 | 4 | 0 | 4 |
| Mu-type opioid receptor | 0 | 2 | 0 | 2 |
| D(3) dopamine receptor | 0 | 2 | 0 | 2 |
| Kappa-type opioid receptor | 0 | 2 | 0 | 2 |
| Alpha-1A adrenergic receptor | 0 | 2 | 0 | 2 |
| Cytochrome P450 2J2 | 0 | 2 | 0 | 2 |
| Spike glycoprotein | 2 | 0 | 0 | 2 |
| Sodium-dependent dopamine transporter | 0 | 4 | 0 | 4 |
| Inositol hexakisphosphate kinase 1 | 2 | 0 | 0 | 2 |
| ATPase family AAA domain-containing protein 5 | 1 | 0 | 0 | 1 |
| cytochrome P450 2C9, partial | 2 | 0 | 0 | 2 |
| DNA polymerase kappa isoform 1 | 1 | 0 | 0 | 1 |
| 5-hydroxytryptamine receptor 4 | 0 | 2 | 0 | 2 |
| Muscarinic acetylcholine receptor M2 | 0 | 2 | 0 | 2 |
| Muscarinic acetylcholine receptor M4 | 0 | 2 | 0 | 2 |
| Muscarinic acetylcholine receptor M5 | 0 | 2 | 0 | 2 |
| Muscarinic acetylcholine receptor M1 | 0 | 2 | 0 | 2 |
| Histamine H2 receptor | 0 | 4 | 0 | 4 |
| Alpha-1D adrenergic receptor | 0 | 2 | 0 | 2 |
| 5-hydroxytryptamine receptor 2C | 0 | 2 | 0 | 2 |
| Histamine H1 receptor | 0 | 0 | 0 | 1 |
| Histamine H2 receptor | 0 | 0 | 0 | 1 |
| Sigma non-opioid intracellular receptor 1 | 0 | 2 | 0 | 2 |
| Histamine H3 receptor | 0 | 0 | 0 | 1 |
| Chain A, Ribulose-1,5 bisphosphate carboxylase/oxygenase large subunit N-methyltransferase, chloroplast | 0 | 1 | 0 | 1 |
| Chain A, Ribulose-1,5 bisphosphate carboxylase/oxygenase large subunit N-methyltransferase, chloroplast | 0 | 1 | 0 | 1 |
| potassium voltage-gated channel subfamily H member 2 isoform d | 1 | 0 | 0 | 1 |
| Glutathione reductase, mitochondrial | 0 | 2 | 0 | 2 |
| Chain A, Beta-lactamase | 1 | 0 | 0 | 1 |
| Chain A, Cruzipain | 1 | 0 | 0 | 1 |
| interleukin 8 | 1 | 0 | 0 | 1 |
| ATAD5 protein, partial | 1 | 0 | 0 | 1 |
| aldehyde dehydrogenase 1 family, member A1 | 1 | 0 | 0 | 1 |
| PINK1 | 1 | 0 | 0 | 1 |
| nonstructural protein 1 | 1 | 0 | 0 | 1 |
| Parkin | 1 | 0 | 0 | 1 |
| IDH1 | 1 | 0 | 0 | 1 |
| nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105), isoform CRA_a | 1 | 0 | 0 | 1 |
| nuclear factor erythroid 2-related factor 2 isoform 2 | 1 | 0 | 0 | 1 |
| transcriptional regulator ERG isoform 3 | 1 | 0 | 0 | 1 |
| cytochrome P450 3A4 isoform 1 | 1 | 0 | 0 | 1 |
| lamin isoform A-delta10 | 3 | 0 | 0 | 3 |
| neuropeptide S receptor isoform A | 1 | 0 | 0 | 1 |
| Gamma-aminobutyric acid receptor subunit pi | 1 | 0 | 0 | 1 |
| Progesterone receptor | 0 | 2 | 1 | 3 |
| Mineralocorticoid receptor | 0 | 1 | 0 | 1 |
| Androgen receptor | 0 | 2 | 2 | 4 |
| Gamma-aminobutyric acid receptor subunit beta-1 | 1 | 0 | 0 | 1 |
| Gamma-aminobutyric acid receptor subunit delta | 1 | 0 | 0 | 1 |
| Gamma-aminobutyric acid receptor subunit gamma-2 | 1 | 0 | 0 | 1 |
| Androgen receptor | 0 | 0 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit alpha-5 | 1 | 0 | 0 | 1 |
| Gamma-aminobutyric acid receptor subunit alpha-3 | 1 | 0 | 0 | 1 |
| Gamma-aminobutyric acid receptor subunit gamma-1 | 1 | 0 | 0 | 1 |
| Gamma-aminobutyric acid receptor subunit alpha-2 | 1 | 0 | 0 | 1 |
| Gamma-aminobutyric acid receptor subunit alpha-4 | 1 | 0 | 0 | 1 |
| Gamma-aminobutyric acid receptor subunit gamma-3 | 1 | 0 | 0 | 1 |
| 5-hydroxytryptamine receptor 1B | 0 | 1 | 0 | 1 |
| Gamma-aminobutyric acid receptor subunit alpha-6 | 1 | 0 | 0 | 1 |
| Alpha-synuclein | 1 | 0 | 0 | 1 |
| Aldo-keto reductase family 1 member C3 | 0 | 1 | 0 | 1 |
| Nuclear receptor ROR-gamma | 1 | 0 | 0 | 1 |
| Aldo-keto reductase family 1 member C2 | 0 | 1 | 0 | 1 |
| Gamma-aminobutyric acid receptor subunit alpha-1 | 1 | 0 | 0 | 1 |
| Gamma-aminobutyric acid receptor subunit beta-3 | 1 | 0 | 0 | 1 |
| Guanine nucleotide-binding protein G | 1 | 0 | 0 | 1 |
| Gamma-aminobutyric acid receptor subunit beta-2 | 1 | 0 | 0 | 1 |
| Aldo-keto reductase family 1 member C1 | 0 | 1 | 0 | 1 |
| GABA theta subunit | 1 | 0 | 0 | 1 |
| Estrogen receptor beta | 0 | 1 | 1 | 2 |
| Gamma-aminobutyric acid receptor subunit epsilon | 1 | 0 | 0 | 1 |
| Chain A, HADH2 protein | 1 | 0 | 0 | 1 |
| Chain B, HADH2 protein | 1 | 0 | 0 | 1 |
| acetylcholinesterase | 1 | 0 | 0 | 1 |
| USP1 protein, partial | 1 | 0 | 0 | 1 |
| hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 1 | 0 | 0 | 1 |
| Carbonic anhydrase 1 | 0 | 1 | 0 | 1 |
| Carbonic anhydrase 2 | 0 | 1 | 0 | 1 |
| Histamine H4 receptor | 0 | 1 | 0 | 1 |
| activating transcription factor 6 | 1 | 0 | 0 | 1 |
| Chain A, PLASMINOGEN | 0 | 0 | 1 | 1 |
| Chain A, PLASMINOGEN | 0 | 0 | 1 | 1 |
| EWS/FLI fusion protein | 1 | 0 | 0 | 1 |
| Plasminogen | 0 | 2 | 1 | 3 |
| Urokinase-type plasminogen activator | 0 | 1 | 0 | 1 |
| [prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023] |