Page last updated: 2024-09-27

Anemia, Diamond-Blackfan

A rare congenital hypoplastic anemia that usually presents early in infancy. The disease is characterized by a moderate to severe macrocytic anemia, occasional neutropenia or thrombocytosis, a normocellular bone marrow with erythroid hypoplasia, and an increased risk of developing leukemia. (Curr Opin Hematol 2000 Mar;7(2):85-94)

Synonyms(1)

Synonym
Anemia, Diamond-Blackfan

Research

Studies (114)

TimeframeStudies, This Condition (%)All Conditions %
pre-199010 (8.77)23.3326
1990's0 (0.00)12.5806
2000's36 (31.58)18.1394
2010's51 (44.74)28.8240
2020's17 (14.91)9.53
DrugIndicatedRelationship StrengthStudiesTrials
toluene0low10
aspirin0low10
busulfan0low40
carbamazepine0low10
deferiprone0low40
deferoxamine0low30
valproic acid0low20
metformin0low10
metoclopramide0medium42
activins0low10
pifithrin0low10
thalidomide0low30
thiotepa0low10
prednisolone0low90
prednisone0low70
sucrose0low10
galactose0low10
tyrosine0low10
leucine0medium81
arginine0low30
methylprednisolone0low10
quinazolines0low10
hydrazine0low20
acetylcysteine0low10
vidarabine0low20
transferrin0medium11
triazoles0low40
fluorodeoxyglucose f180low10
moxifloxacin0low10
deflazacort0low10
deferasirox0low50
lenalidomide0low30
cortisone0low20
leupeptins0low10
lithium chloride0low10
benzyloxycarbonylleucyl-leucyl-leucine aldehyde0low10
isomethyleugenol0low10
fludarabine0low20
ace-0110low20
ginsenosides0low10
4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1h-imidazol-2-yl)benzamide0low20
sirolimus0low10
lactacystin0low10
treosulfan0low10
ginsenoside rb10low10
ly-21572990low10
nutlin-3a0low10
losartan potassium0low60
sepharose0low10
sb 2901570low10
heme0low90
transforming growth factor beta0low10
cyclosporine0low60
dacarbazine0low10
amg5310low20

Protein Targets (1,001)

ProteinPotency MeasurementsInhibition MeasurementsActivation MeasurementsDrugs
Chain A, TYROSYL-DNA PHOSPHODIESTERASE6006
Chain A, HADH2 protein6006
Chain B, HADH2 protein6006
Chain A, 2-oxoglutarate Oxygenase7007
Chain A, TGF-beta receptor type-10101
Luciferase5005
USP1 protein, partial7007
TDP1 protein150015
aldehyde dehydrogenase 1 family, member A1110011
EWS/FLI fusion protein140014
cytochrome P450 2D6 isoform 12002
cytochrome P450 2C19 precursor3003
15-hydroxyprostaglandin dehydrogenase [NAD(+)] isoform 14004
mitogen-activated protein kinase 13003
tyrosine-protein kinase Yes1001
cytochrome P450 3A4 isoform 15005
histone acetyltransferase KAT2A isoform 14004
lethal factor (plasmid)6006
Serine/threonine-protein kinase PLK40033
Serine/threonine-protein kinase 250011
Gamma-aminobutyric acid receptor subunit pi5005
Citron Rho-interacting kinase0033
Serine/threonine-protein kinase RIO30011
Serine/threonine-protein kinase Chk10033
Aurora kinase A0033
Cyclin-G-associated kinase0033
Serine/threonine-protein kinase DCLK10011
Muscle, skeletal receptor tyrosine-protein kinase0011
Polyunsaturated fatty acid lipoxygenase ALOX15B1001
3-phosphoinositide-dependent protein kinase 10011
Death-associated protein kinase 30011
Receptor-interacting serine/threonine-protein kinase 20134
NUAK family SNF1-like kinase 10011
Tyrosine-protein kinase JAK20022
Ribosomal protein S6 kinase alpha-50033
Ribosomal protein S6 kinase alpha-40033
Serine/threonine-protein kinase 160033
Serine/threonine-protein kinase PAK 30011
Serine/threonine-protein kinase 17B0011
Serine/threonine-protein kinase 100033
Serine/threonine-protein kinase D30033
Cyclin-dependent kinase 140011
Mitogen-activated protein kinase kinase kinase kinase 40134
Serine/threonine-protein kinase LATS10033
Serine/threonine-protein kinase PAK 40033
Tyrosine-protein kinase ABL10045
Epidermal growth factor receptor0235
RAF proto-oncogene serine/threonine-protein kinase0011
Receptor tyrosine-protein kinase erbB-20011
High affinity nerve growth factor receptor0033
Insulin receptor0033
Tyrosine-protein kinase Lck0033
Tyrosine-protein kinase Fyn0033
Tyrosine-protein kinase Fes/Fps0033
Macrophage colony-stimulating factor 1 receptor0011
Tyrosine-protein kinase Yes0033
Tyrosine-protein kinase Lyn0033
Proto-oncogene tyrosine-protein kinase receptor Ret0033
Insulin-like growth factor 1 receptor0033
Hepatocyte growth factor receptor0033
Tyrosine-protein kinase HCK0033
Proto-oncogene tyrosine-protein kinase ROS0011
Platelet-derived growth factor receptor beta0033
Tyrosine-protein kinase Fgr0022
Mast/stem cell growth factor receptor Kit0011
Serine/threonine-protein kinase pim-10033
Fibroblast growth factor receptor 10033
Myosin light chain kinase, smooth muscle0011
Proto-oncogene tyrosine-protein kinase Src0033
Insulin receptor-related protein0011
Serine/threonine-protein kinase B-raf0033
Gamma-aminobutyric acid receptor subunit beta-15005
Phosphorylase b kinase gamma catalytic chain, liver/testis isoform0033
Platelet-derived growth factor receptor alpha0011
Tyrosine-protein kinase Fer0033
cAMP-dependent protein kinase catalytic subunit alpha0033
Vascular endothelial growth factor receptor 1 0011
Gamma-aminobutyric acid receptor subunit delta5005
Gamma-aminobutyric acid receptor subunit gamma-25005
Interferon-induced, double-stranded RNA-activated protein kinase0011
Casein kinase II subunit alpha'0033
Gamma-aminobutyric acid receptor subunit alpha-55005
Gamma-aminobutyric acid receptor subunit alpha-35005
Cyclin-dependent kinase 11B0011
Ephrin type-A receptor 10022
Fibroblast growth factor receptor 20011
Fibroblast growth factor receptor 40011
Fibroblast growth factor receptor 30011
cAMP-dependent protein kinase catalytic subunit beta0033
Tyrosine-protein kinase JAK10033
Gamma-aminobutyric acid receptor subunit gamma-15005
Gamma-aminobutyric acid receptor subunit alpha-25005
Protein kinase C eta type0011
Cyclin-dependent kinase 20044
Activin receptor type-2A0011
Mitogen-activated protein kinase 3 0033
MAP/microtubule affinity-regulating kinase 30033
Gamma-aminobutyric acid receptor subunit alpha-45005
Gamma-aminobutyric acid receptor subunit gamma-35005
Mitogen-activated protein kinase 10033
Ephrin type-A receptor 20033
Ephrin type-A receptor 30011
Ephrin type-A receptor 80011
Ephrin type-B receptor 20033
Leukocyte tyrosine kinase receptor0011
Non-receptor tyrosine-protein kinase TYK20033
Gamma-aminobutyric acid receptor subunit alpha-65005
Wee1-like protein kinase0033
Tyrosine-protein kinase receptor UFO0011
Mitogen-activated protein kinase 40011
RAC-alpha serine/threonine-protein kinase0033
RAC-beta serine/threonine-protein kinase0033
Dual specificity protein kinase TTK0033
Tyrosine-protein kinase receptor Tie-10011
Vascular endothelial growth factor receptor 30011
Vascular endothelial growth factor receptor 20112
Dual specificity mitogen-activated protein kinase kinase 20033
Receptor-type tyrosine-protein kinase FLT30033
Bone morphogenetic protein receptor type-1A0033
Activin receptor type-1B0134
TGF-beta receptor type-10347
Serine/threonine-protein kinase receptor R30022
TGF-beta receptor type-20235
Tyrosine-protein kinase CSK0033
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform0011
Tyrosine-protein kinase Tec0033
Tyrosine-protein kinase TXK0011
Tyrosine-protein kinase ABL20033
Tyrosine-protein kinase FRK0033
Tyrosine-protein kinase ZAP-700011
Tyrosine-protein kinase SYK0033
Mitogen-activated protein kinase 80033
Mitogen-activated protein kinase 90033
Dual specificity mitogen-activated protein kinase kinase 40011
Dual specificity mitogen-activated protein kinase kinase 30033
Histamine H2 receptor2002
Casein kinase I isoform delta0033
MAP kinase-activated protein kinase 20033
Cyclin-dependent kinase 80011
Casein kinase I isoform epsilon0033
Dual specificity protein kinase CLK10033
Dual specificity protein kinase CLK20033
Dual specificity protein kinase CLK30022
Glycogen synthase kinase-3 alpha0033
Glycogen synthase kinase-3 beta0145
Cyclin-dependent kinase 70033
Cyclin-dependent kinase 90033
Tyrosine-protein kinase Blk0011
Ribosomal protein S6 kinase alpha-30033
Cytoplasmic tyrosine-protein kinase BMX0011
cAMP-dependent protein kinase catalytic subunit PRKX0011
Serine/threonine-protein kinase Nek20033
Tyrosine-protein kinase JAK30011
Dual specificity mitogen-activated protein kinase kinase 60033
Serine/threonine-protein kinase PLK10033
Death-associated protein kinase 10112
LIM domain kinase 10033
LIM domain kinase 20033
Mitogen-activated protein kinase 120011
Mitogen-activated protein kinase 100033
5'-AMP-activated protein kinase catalytic subunit alpha-20022
Ephrin type-B receptor 30033
Ephrin type-A receptor 50033
Ephrin type-B receptor 40033
Ephrin type-B receptor 10011
Ephrin type-A receptor 40033
Serine/threonine-protein kinase SIK10011
Gamma-aminobutyric acid receptor subunit alpha-15106
Gamma-aminobutyric acid receptor subunit beta-35005
Gamma-aminobutyric acid receptor subunit beta-25005
Tubulin alpha-1A chain0011
Casein kinase II subunit alpha0011
Phosphatidylinositol 5-phosphate 4-kinase type-2 beta0011
SRSF protein kinase 20011
Casein kinase I isoform gamma-20033
Mitogen-activated protein kinase kinase kinase 90011
Inositol monophosphatase 12002
Cyclin-dependent kinase 30022
Cyclin-dependent-like kinase 5 0033
Cyclin-dependent kinase 160033
Cyclin-dependent kinase 170033
Protein kinase C epsilon type0011
Dual specificity mitogen-activated protein kinase kinase 10033
Angiopoietin-1 receptor0011
Mitogen-activated protein kinase kinase kinase 100011
Protein kinase C theta type0033
Activin receptor type-10033
Focal adhesion kinase 10033
Protein kinase C delta type0033
Tyrosine-protein kinase BTK0033
Tyrosine-protein kinase receptor TYRO30011
Cyclin-dependent kinase 180022
Activated CDC42 kinase 10033
Epithelial discoidin domain-containing receptor 10033
Tyrosine-protein kinase ITK/TSK0011
Myotonin-protein kinase0011
Tyrosine-protein kinase Mer0022
Serine/threonine-protein kinase 40033
5'-AMP-activated protein kinase catalytic subunit alpha-10033
Serine/threonine-protein kinase PAK 10011
Mitogen-activated protein kinase 70033
Serine/threonine-protein kinase PAK 20033
Serine/threonine-protein kinase 30033
cGMP-dependent protein kinase 20011
Non-receptor tyrosine-protein kinase TNK10033
Receptor-interacting serine/threonine-protein kinase 10011
Calcium/calmodulin-dependent protein kinase type II subunit beta0011
Calcium/calmodulin-dependent protein kinase type II subunit gamma0033
Calcium/calmodulin-dependent protein kinase type II subunit delta0033
Activin receptor type-2B0033
Bone morphogenetic protein receptor type-20033
Protein-tyrosine kinase 60033
cGMP-dependent protein kinase 1 0033
Calcium/calmodulin-dependent protein kinase type 10011
Inhibitor of nuclear factor kappa-B kinase subunit epsilon0033
Protein-tyrosine kinase 2-beta0033
Maternal embryonic leucine zipper kinase0033
Serine/threonine-protein kinase D10011
Ribosomal protein S6 kinase alpha-20011
Ephrin type-A receptor 70022
Ribosomal protein S6 kinase alpha-10033
Dual specificity testis-specific protein kinase 10033
Myosin light chain kinase, smooth muscle0033
Mitogen-activated protein kinase 110033
Serine/threonine-protein kinase STK110033
NT-3 growth factor receptor0011
Serine/threonine-protein kinase N10033
Serine/threonine-protein kinase N20033
Mitogen-activated protein kinase 140134
Calcium/calmodulin-dependent protein kinase type IV0033
Mitogen-activated protein kinase kinase kinase 110033
BDNF/NT-3 growth factors receptor0011
Mitogen-activated protein kinase 60011
Phosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoform0011
Discoidin domain-containing receptor 20033
AP2-associated protein kinase 10033
Serine/threonine-protein kinase TNNI3K0011
Serine/threonine-protein kinase MRCK alpha0033
Serine/threonine-protein kinase MRCK gamma0033
Serine/threonine-protein kinase Nek50011
Serine/threonine-protein kinase MARK20033
Serine/threonine-protein kinase tousled-like 20011
Serine/threonine-protein kinase 32C0011
Serine/threonine-protein kinase pim-30011
Myosin light chain kinase family member 40011
Calcium/calmodulin-dependent protein kinase type 1D0011
Mitogen-activated protein kinase kinase kinase kinase 30033
MAP kinase-activated protein kinase 50033
Serine/threonine-protein kinase BRSK20011
Serine/threonine-protein kinase DCLK20011
Calcium/calmodulin-dependent protein kinase kinase 10011
Casein kinase I isoform alpha-like0011
Myosin-IIIa0011
Ankyrin repeat and protein kinase domain-containing protein 10011
Atypical kinase COQ8A, mitochondrial0033
Mitogen-activated protein kinase 150033
Serine/threonine-protein kinase Nek90033
Serine/threonine-protein kinase BRSK10011
Serine/threonine-protein kinase Nek70022
Myosin-IIIb0011
GABA theta subunit5005
Mitogen-activated protein kinase kinase kinase kinase 10033
Atypical kinase COQ8B, mitochondrial0011
Aurora kinase B0134
MAP/microtubule affinity-regulating kinase 40022
Calcium/calmodulin-dependent protein kinase type 1G0022
Serine/threonine-protein kinase Nek10033
Calcium/calmodulin-dependent protein kinase kinase 20033
SRSF protein kinase 10011
Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase0033
Mitogen-activated protein kinase kinase kinase 50033
Phosphatidylinositol 4-phosphate 5-kinase type-1 alpha0011
Serine/threonine-protein kinase RIO10011
MAP kinase-interacting serine/threonine-protein kinase 10011
Cyclin-dependent kinase 190011
Testis-specific serine/threonine-protein kinase 10011
Serine/threonine-protein kinase 330011
Serine/threonine-protein kinase D20033
Serine/threonine-protein kinase DCLK30011
Gamma-aminobutyric acid receptor subunit epsilon5005
NUAK family SNF1-like kinase 20022
Serine/threonine-protein kinase SIK20033
Myosin light chain kinase 2, skeletal/cardiac muscle0011
STE20-like serine/threonine-protein kinase 0033
Tyrosine-protein kinase Srms0011
Serine/threonine-protein kinase PLK30011
Dual specificity protein kinase CLK40033
MAP kinase-interacting serine/threonine-protein kinase 20011
Serine/threonine-protein kinase Nek60011
Casein kinase I isoform gamma-10033
Serine/threonine-protein kinase PAK 60022
Serine/threonine-protein kinase LATS20011
Serine/threonine-protein kinase 360011
BMP-2-inducible protein kinase0033
Serine/threonine-protein kinase 32B0011
Mitogen-activated protein kinase kinase kinase 200033
Serine/threonine-protein kinase MARK10011
Serine/threonine-protein kinase pim-20022
Serine/threonine-protein kinase PAK 50011
Serine/threonine-protein kinase 260033
eIF-2-alpha kinase GCN20011
Serine/threonine-protein kinase NLK0033
Serine/threonine-protein kinase 17A0011
Ephrin type-A receptor 60011
Death-associated protein kinase 20011
Ribosomal protein S6 kinase alpha-60033
TRAF2 and NCK-interacting protein kinase0033
Serine/threonine-protein kinase tousled-like 10011
ALK tyrosine kinase receptor0022
Cyclin-dependent kinase 11A0011
Aurora kinase C0011
Calcium/calmodulin-dependent protein kinase type II subunit alpha0011
RAC-gamma serine/threonine-protein kinase0033
Serine/threonine-protein kinase 38-like0011
Dual specificity tyrosine-phosphorylation-regulated kinase 1B0033
Mitogen-activated protein kinase kinase kinase kinase 50033
Serine/threonine-protein kinase MRCK beta0033
Interleukin-1 receptor-associated kinase 30033
Serine/threonine-protein kinase 240033
Casein kinase I isoform gamma-30033
Mitogen-activated protein kinase kinase kinase 40033
Chain A, JmjC domain-containing histone demethylation protein 3A3003
Chain A, ATP-DEPENDENT DNA HELICASE Q11001
acetylcholinesterase6006
dopamine D1 receptor3003
15-lipoxygenase, partial4004
pregnane X receptor4004
phosphopantetheinyl transferase4004
RAR-related orphan receptor gamma9009
NFKB1 protein, partial2002
Microtubule-associated protein tau3003
Thrombopoietin1001
AR protein140014
regulator of G-protein signaling 43003
glucocorticoid receptor [Homo sapiens]140014
retinoic acid nuclear receptor alpha variant 1130013
retinoid X nuclear receptor alpha9009
farnesoid X nuclear receptor7007
estrogen nuclear receptor alpha180018
vitamin D (1,25- dihydroxyvitamin D3) receptor6006
arylsulfatase A3003
euchromatic histone-lysine N-methyltransferase 2120012
Bloom syndrome protein isoform 14004
D(1A) dopamine receptor3003
thyroid hormone receptor beta isoform a5005
thyroid hormone receptor beta isoform 27007
heat shock protein beta-14004
flap endonuclease 15005
geminin150015
peripheral myelin protein 224004
survival motor neuron protein isoform d7007
muscarinic acetylcholine receptor M16006
Histone deacetylase 30303
Solute carrier family 22 member 60202
Histone deacetylase 40303
Guanine nucleotide-binding protein G2002
Histone deacetylase 10404
Histone deacetylase 70303
Histone deacetylase 20303
Polyamine deacetylase HDAC100303
Histone deacetylase 11 0303
Ataxin-26006
Histone deacetylase 80303
Histone deacetylase 60303
Histone deacetylase 90303
Histone deacetylase 50303
ATP-dependent phosphofructokinase5005
hypoxia-inducible factor 1 alpha subunit7007
estrogen receptor 2 (ER beta)4004
progesterone receptor9009
cytochrome P450 family 3 subfamily A polypeptide 4100010
G4004
cytochrome P450 2D67007
peroxisome proliferator-activated receptor delta5005
peroxisome proliferator activated receptor gamma7007
nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105), isoform CRA_a6006
v-jun sarcoma virus 17 oncogene homolog (avian)6006
Histone H2A.x4004
nuclear factor erythroid 2-related factor 2 isoform 1100010
Solute carrier family 22 member 1 0404
Solute carrier organic anion transporter family member 2B1 0101
Interferon beta8008
HLA class I histocompatibility antigen, B alpha chain 4004
Replicase polyprotein 1ab0303
Replicase polyprotein 1ab0314
Thrombopoietin receptor0011
Potassium voltage-gated channel subfamily H member 20607
Sodium channel protein type 5 subunit alpha0303
Inositol hexakisphosphate kinase 14004
Solute carrier organic anion transporter family member 1B30102
Potassium voltage-gated channel subfamily D member 30202
Broad substrate specificity ATP-binding cassette transporter ABCG20203
Solute carrier organic anion transporter family member 1B10202
cytochrome P450 2C9, partial4004
Chain A, MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASE6006
Chain E, LYSINE, ARGININE, ORNITHINE-BINDING PROTEIN0011
Chain E, LYSINE, ARGININE, ORNITHINE-BINDING PROTEIN0011
Chain E, LYSINE, ARGININE, ORNITHINE-BINDING PROTEIN0011
thioredoxin reductase6006
GLS protein4004
thyroid stimulating hormone receptor8008
alpha-galactosidase2002
chromobox protein homolog 18008
DNA polymerase iota isoform a (long)5005
Cytochrome P450 3A40405
Nitric oxide synthase, endothelial0002
Nitric oxide synthase, brain0001
Nitric oxide synthase, brain 0001
Nitric oxide synthase, inducible0001
Nitric oxide synthase, inducible0013
Cationic amino acid transporter 30101
Chain A, Phospholipase A2 isoform 30011
GTP-binding protein (rab7)0011
ras protein, partial0011
interleukin 82002
hypothetical protein, conserved1001
estrogen-related nuclear receptor alpha140014
glucocerebrosidase2002
Rac1 protein0011
IDH17007
cell division cycle 42 (GTP binding protein, 25kDa), partial0011
DNA polymerase kappa isoform 13003
Prostaglandin-H2 D-isomerase0101
ATP-binding cassette sub-family C member 3014014
Multidrug resistance-associated protein 4014015
Prostaglandin G/H synthase 1 0101
Prostaglandin G/H synthase 2 0101
Bile salt export pump019019
Carbonic anhydrase 10203
Carbonic anhydrase 20326
Fatty acid-binding protein, liver0202
Integrin beta-32103
Myeloperoxidase0202
Prostaglandin G/H synthase 10202
Seed linoleate 13S-lipoxygenase-10101
Integrin alpha-IIb2103
Glutathione hydrolase 1 proenzyme0101
Prostaglandin G/H synthase 10202
Adenosine receptor A10102
Adenosine receptor A2a0102
Substance-P receptor0101
Prostaglandin G/H synthase 20303
Urotensin-2 receptor0101
4-aminobutyrate aminotransferase, mitochondrial0101
Nuclear receptor ROR-gamma3003
Ras-related protein Rab-2A0011
Prostaglandin G/H synthase 20202
Rho-associated protein kinase 20101
Nicotinate phosphoribosyltransferase0101
Solute carrier family 22 member 200202
Solute carrier family 22 member 60202
Canalicular multispecific organic anion transporter 1013013
Sigma non-opioid intracellular receptor 10011
Sigma non-opioid intracellular receptor 10011
Proteasome subunit beta type-110202
Fumarate hydratase3003
PPM1D protein3003
polyprotein3003
vitamin D3 receptor isoform VDRA4004
Calpain-90101
Proteasome subunit alpha type-70202
Cathepsin B0101
Aromatase0101
Indoleamine 2,3-dioxygenase 10101
Calpain-2 catalytic subunit0101
Proteasome subunit beta type-10303
Proteasome subunit alpha type-10202
Proteasome subunit alpha type-20202
Proteasome subunit alpha type-30202
Proteasome subunit alpha type-40202
NF-kappa-B inhibitor alpha0011
Proteasome subunit beta type-80202
Proteasome subunit beta type-90202
Proteasome subunit alpha type-50202
Proteasome subunit beta type-40202
Proteasome subunit beta type-60202
Proteasome subunit beta type-50303
Proteasome subunit beta type-100202
Cathepsin K0101
Proteasome subunit beta type-30202
Proteasome subunit beta type-20303
Proteasome subunit alpha type-60202
Proteasome subunit alpha-type 80202
Proteasome subunit beta type-70202
Gamma-secretase subunit PEN-20101
apical membrane antigen 1, AMA13003
pregnane X nuclear receptor9009
aryl hydrocarbon receptor3003
ubiquitin carboxyl-terminal hydrolase 2 isoform a1001
lamin isoform A-delta109009
Matrix metalloproteinase-90202
Disintegrin and metalloproteinase domain-containing protein 171001
Chain A, Beta-lactamase2002
cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a100010
nuclear factor erythroid 2-related factor 2 isoform 27007
Vpr1001
Bile salt export pump0303
Albumin0022
Major prion protein0011
Cellular tumor antigen p53102012
Sodium channel protein type 1 subunit alpha0101
Sodium channel protein type 2 subunit alpha0101
Sodium channel protein type 3 subunit alpha0101
Cytochrome P450 2C9 0404
UDP-glucuronosyltransferase 2B70103
Cytochrome P450 2B60112
Sodium channel protein type 4 subunit alpha0102
Cytochrome P450 2J20202
Sodium channel protein type 9 subunit alpha0202
Frizzled-80011
P2X purinoceptor 40101
endonuclease IV1001
GLI family zinc finger 37007
peripheral myelin protein 22 isoform 11001
atrial natriuretic peptide receptor 1 precursor1001
M-phase phosphoprotein 82002
Glucocorticoid receptor08215
Sex hormone-binding globulin0011
Glycine receptor subunit alpha-10808
Corticosteroid-binding globulin0202
Glycine receptor subunit beta0808
Glycine receptor subunit alpha-20808
Glycine receptor subunit alpha-30808
Potassium voltage-gated channel subfamily A member 10011
TAR DNA-binding protein 432002
Multidrug and toxin extrusion protein 10303
thyroid stimulating hormone receptor3003
activating transcription factor 62002
Isocitrate lyase0101
SMAD family member 21001
SMAD family member 31001
nuclear receptor subfamily 1, group I, member 36006
Lysine-specific demethylase 6B0101
Lysine-specific demethylase 4A0314
Voltage-dependent calcium channel gamma-2 subunit3003
Glutamate receptor 23003
Lysine-specific demethylase 5A0101
Flavin reductase (NADPH)0011
Voltage-dependent L-type calcium channel subunit alpha-1C0202
Chain A, Putative fructose-1,6-bisphosphate aldolase1001
nonstructural protein 12002
bromodomain adjacent to zinc finger domain 2B2002
cytochrome P450 2C9 precursor1001
Lysine-specific demethylase 6A0101
Lysine-specific demethylase 5C0101
Spike glycoprotein3003
Lysine-specific demethylase 2B0101
Deoxyhypusine hydroxylase0202
Lysine-specific demethylase 2A0101
67.9K protein5005
urokinase-type plasminogen activator precursor3003
plasminogen precursor3003
urokinase plasminogen activator surface receptor precursor3003
Hypoxia-inducible factor 1-alpha0011
Methylcytosine dioxygenase TET20101
nuclear receptor subfamily 1, group I, member 23003
ATPase family AAA domain-containing protein 55005
Smad33003
hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)3003
corticotropin-releasing hormone receptor 20112
corticotropin releasing factor-binding protein0112
glycogen synthase kinase-3 beta isoform 10022
5'-nucleotidase0101
Adenosine receptor A30101
Adenosine deaminase 0002
importin subunit beta-1 isoform 12002
snurportin-12002
Beta-galactosidase0101
Lipopolysaccharide heptosyltransferase 10101
PA-I galactophilic lectin0011
Jacalin0011
DNA topoisomerase 10101
DNA topoisomerase 2-alpha0124
Kappa-type opioid receptor0101
5'-AMP-activated protein kinase subunit gamma-10033
5'-AMP-activated protein kinase subunit beta-10011
nuclear receptor ROR-gamma isoform 14004
Splicing factor 3B subunit 30101
Cereblon isoform 40303
Bromodomain-containing protein 40101
Breakpoint cluster region protein0023
DNA-binding protein Ikaros0014
DNA damage-binding protein 10213
Protein cereblon0429
Zinc finger protein Aiolos0011
Chain A, AMINOPEPTIDASE0101
Chain A, AMINOPEPTIDASE0101
Chain A, Leucine Aminopeptidase0101
Alkaline phosphatase, tissue-nonspecific isozyme0101
Intestinal-type alkaline phosphatase0101
Large neutral amino acids transporter small subunit 10202
Proton-coupled amino acid transporter 10102
Phospholipase A-2-activating protein0101
potassium voltage-gated channel subfamily H member 2 isoform d2002
inositol monophosphatase 11001
Cholecystokinin receptor type A1001
Gastrin/cholecystokinin type B receptor1001
Type-1A angiotensin II receptor 0101
Type-1B angiotensin II receptor0202
Type-2 angiotensin II receptor0101
cGMP-inhibited 3',5'-cyclic phosphodiesterase B0101
cGMP-inhibited 3',5'-cyclic phosphodiesterase A0101
5-hydroxytryptamine receptor 1A0101
Type-1 angiotensin II receptor0101
Bone morphogenetic protein receptor type-1B0022
Membrane-associated progesterone receptor component 10011
ATP-dependent RNA helicase DDX3X0022
Pyridoxal kinase0022
Ephrin type-B receptor 60022
Peroxisomal acyl-coenzyme A oxidase 30022
Mitotic checkpoint serine/threonine-protein kinase BUB10022
Dynamin-like 120 kDa protein, mitochondrial0022
Rho-associated protein kinase 20022
Serine/threonine-protein kinase ULK10022
Serine/threonine-protein kinase/endoribonuclease IRE10022
U5 small nuclear ribonucleoprotein 200 kDa helicase0022
Structural maintenance of chromosomes protein 20022
Mitogen-activated protein kinase kinase kinase 60022
Guanine nucleotide-binding protein G(i) subunit alpha-20011
ADP/ATP translocase 20022
Protein kinase C beta type0022
Cyclin-dependent kinase 10022
Glycogen phosphorylase, liver form0022
Signal recognition particle receptor subunit alpha0022
Cytochrome c1, heme protein, mitochondrial0022
Serine/threonine-protein kinase A-Raf0022
Cytochrome P450 2D60404
Glycogen phosphorylase, brain form0022
Cyclin-dependent kinase 40022
ADP/ATP translocase 30022
Inosine-5'-monophosphate dehydrogenase 20022
cAMP-dependent protein kinase type II-alpha regulatory subunit0022
Ribosyldihydronicotinamide dehydrogenase [quinone]0022
Protein kinase C alpha type0022
General transcription and DNA repair factor IIH helicase subunit XPD0022
Ras-related protein Rab-6A0022
Multifunctional protein ADE20022
cAMP-dependent protein kinase catalytic subunit gamma0011
Ferrochelatase, mitochondrial0022
Ribosomal protein S6 kinase beta-10022
Beta-adrenergic receptor kinase 10022
Probable ATP-dependent RNA helicase DDX60022
Deoxycytidine kinase0022
Phosphatidylethanolamine-binding protein 10022
Heme oxygenase 20022
S-adenosylmethionine synthase isoform type-20022
DnaJ homolog subfamily A member 10022
DNA replication licensing factor MCM40022
Electron transfer flavoprotein subunit beta0022
Glycine--tRNA ligase0022
Protein kinase C iota type0022
Exosome RNA helicase MTR40022
G protein-coupled receptor kinase 60022
26S proteasome regulatory subunit 6B0022
Phosphatidylinositol 5-phosphate 4-kinase type-2 alpha0022
Casein kinase I isoform alpha0022
Elongation factor Tu, mitochondrial0022
Cysteine--tRNA ligase, cytoplasmic0022
Very long-chain specific acyl-CoA dehydrogenase, mitochondrial0022
Ras-related protein Rab-27A0022
Interleukin-1 receptor-associated kinase 10022
Serine/threonine-protein kinase Nek30022
Tyrosine--tRNA ligase, cytoplasmic0022
Adenylate kinase 2, mitochondrial0022
Adenosine kinase0022
Ras-related protein Rab-100022
Actin-related protein 30022
Actin-related protein 20022
D(2) dopamine receptor0303
GTP-binding nuclear protein Ran0022
Cyclin-dependent kinase 60022
ATP-dependent 6-phosphofructokinase, platelet type0022
DNA topoisomerase 2-beta0022
Macrophage-stimulating protein receptor0022
Mitogen-activated protein kinase kinase kinase kinase 20022
Dual specificity mitogen-activated protein kinase kinase 50022
Mitogen-activated protein kinase kinase kinase 10022
Integrin-linked protein kinase0022
Rho-associated protein kinase 10022
Serine/threonine-protein kinase ATR0011
Dual specificity tyrosine-phosphorylation-regulated kinase 1A0022
Cyclin-dependent kinase 130022
Structural maintenance of chromosomes protein 1A0022
Chromodomain-helicase-DNA-binding protein 40022
Peroxisomal acyl-coenzyme A oxidase 10022
Delta(24)-sterol reductase0022
Myosin light chain kinase 30022
Putative heat shock protein HSP 90-beta 20022
Rab-like protein 30011
TGF-beta receptor type-10101
Acyl-CoA dehydrogenase family member 100022
Serine/threonine-protein kinase ULK30022
Uncharacterized protein FLJ452520022
Acyl-CoA dehydrogenase family member 110022
Serine/threonine-protein kinase/endoribonuclease IRE20022
ATP-dependent RNA helicase DHX300022
Serine/threonine-protein kinase TAO10022
STE20-related kinase adapter protein alpha0022
Myosin-140022
AarF domain-containing protein kinase 10022
ATP-dependent RNA helicase DDX420011
Eukaryotic peptide chain release factor GTP-binding subunit ERF3B0011
Misshapen-like kinase 10022
Phosphatidylinositol 5-phosphate 4-kinase type-2 gamma0022
ATP-dependent RNA helicase DDX10022
PAS domain-containing serine/threonine-protein kinase0022
EKC/KEOPS complex subunit TP53RK0022
Dual specificity testis-specific protein kinase 20022
Mitogen-activated protein kinase kinase kinase 30022
Eukaryotic translation initiation factor 2-alpha kinase 10022
Nucleolar GTP-binding protein 10022
RNA cytidine acetyltransferase0022
Serine/threonine-protein kinase TAO30022
dCTP pyrophosphatase 10022
Phenylalanine--tRNA ligase beta subunit0022
Isoleucine--tRNA ligase, mitochondrial0022
Obg-like ATPase 10022
Midasin0022
Interleukin-1 receptor-associated kinase 40022
Cyclin-dependent kinase 120022
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 130011
Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial0022
5'-AMP-activated protein kinase subunit gamma-20022
Serine/threonine-protein kinase TBK10022
Septin-90022
Serine/threonine-protein kinase TAO20022
Long-chain-fatty-acid--CoA ligase 50011
Serine/threonine-protein kinase ICK0022
Serine/threonine-protein kinase SIK30022
Mitogen-activated protein kinase kinase kinase 20022
Receptor-interacting serine/threonine-protein kinase 30022
Chain A, Ferritin light chain2002
Solute carrier family 22 member 20202
Dihydrofolate reductase0304
Dipeptidyl peptidase 40202
Solute carrier family 22 member 10001
Chain B, DIHYDROFOLATE REDUCTASE0011
Chain B, DIHYDROFOLATE REDUCTASE0011
Chain B, DIHYDROFOLATE REDUCTASE0011
acid sphingomyelinase1001
ClpP1001
ATAD5 protein, partial2002
Thymidylate synthase 0101
Thymidylate synthase 0101
cellular tumor antigen p53 isoform a2002
polyunsaturated fatty acid lipoxygenase ALOX122002
transcriptional regulator ERG isoform 31001
DNA polymerase beta1001
nuclear receptor coactivator 1 isoform 1 [Homo sapiens]0101
peptidyl-prolyl cis-trans isomerase NIMA-interacting 11001
DNA polymerase eta isoform 11001
transactivating tegument protein VP16 [Human herpesvirus 1]0101
muscleblind-like protein 1 isoform 12002
caspase-1 isoform alpha precursor1001
nuclear receptor coactivator 3 isoform a0101
Toll-like receptor 40101
Fatty-acid amide hydrolase 10101
ATP-binding cassette sub-family C member 30102
Dihydrofolate reductase0203
Dihydrofolate reductase 0101
Dihydrofolate reductase0101
Dihydrofolate reductase0101
Dihydrofolate reductase0203
Thymidylate synthase0101
Thymidylate synthase0202
Bifunctional dihydrofolate reductase-thymidylate synthase0101
Thymidylate synthase0202
5-hydroxytryptamine receptor 2C0203
High mobility group protein B10011
Dihydrofolate reductase0101
Thymidylate synthase0101
Dihydrofolate reductase0224
Glucose-6-phosphate 1-dehydrogenase0101
Bifunctional dihydrofolate reductase-thymidylate synthase0101
Folate receptor beta0101
5-hydroxytryptamine receptor 2A0202
Cytochrome P450 11B1, mitochondrial 0101
Folate receptor alpha0101
Dihydrofolate reductase0202
Histidine decarboxylase0101
Trifunctional purine biosynthetic protein adenosine-30101
Bifunctional purine biosynthesis protein ATIC0202
Multidrug resistance-associated protein 1 0001
Delta-type opioid receptor0101
Mu-type opioid receptor0101
Kappa-type opioid receptor0101
Reduced folate transporter0202
Folylpolyglutamate synthase, mitochondrial0103
6-phosphogluconate dehydrogenase, decarboxylating0202
Caspase-71001
Solute carrier organic anion transporter family member 1A30001
Dihydrofolate reductase0101
Pteridine reductase 10101
Folylpolyglutamate synthase, mitochondrial0103
Bifunctional dihydrofolate reductase-thymidylate synthase0101
Bifunctional dihydrofolate reductase-thymidylate synthase0101
Solute carrier family 22 member 60001
Canalicular multispecific organic anion transporter 10102
Trifunctional purine biosynthetic protein adenosine-30101
Dihydrofolate reductase 0101
Solute carrier family 22 member 80001
Dihydrofolate reductase0101
ATP-binding cassette sub-family C member 110001
Proton-coupled folate transporter0101
Multidrug resistance associated protein0102
Solute carrier family 22 member 110001
Protein-arginine deiminase type-40101
Nuclear receptor subfamily 1 group I member 20022
Androgen receptor0303
Nuclear receptor subfamily 1 group I member 20011
5-hydroxytryptamine receptor 3E0011
5-hydroxytryptamine receptor 40404
5-hydroxytryptamine receptor 3B0011
Alpha-2A adrenergic receptor0404
D(2) dopamine receptor0202
Alpha-1B adrenergic receptor0101
D0101
D(3) dopamine receptor0101
5-hydroxytryptamine receptor 1A0101
Alpha-2B adrenergic receptor0101
D(2) dopamine receptor0101
Alpha-2C adrenergic receptor0101
Acetylcholinesterase0202
Alpha-2A adrenergic receptor0101
Alpha-1D adrenergic receptor0101
5-hydroxytryptamine receptor 3A0101
D(1B) dopamine receptor0101
5-hydroxytryptamine receptor 2A0404
5-hydroxytryptamine receptor 2C0404
5-hydroxytryptamine receptor 1B0101
5-hydroxytryptamine receptor 1D0101
D(4) dopamine receptor0101
5-hydroxytryptamine receptor 1F0101
5-hydroxytryptamine receptor 2B0101
D(3) dopamine receptor0404
5-hydroxytryptamine receptor 3A0202
5-hydroxytryptamine receptor 2B0202
Alpha-1A adrenergic receptor0101
5-hydroxytryptamine receptor 3A0011
5-hydroxytryptamine receptor 70101
Lactoperoxidase0101
5-hydroxytryptamine receptor 4 0102
5-hydroxytryptamine receptor 3D0011
5-hydroxytryptamine receptor 3C0011
5-hydroxytryptamine receptor 3B0101
5-hydroxytryptamine receptor 3B0202
Voltage-dependent L-type calcium channel subunit alpha-1C0101
Voltage-dependent L-type calcium channel subunit alpha-1F0101
DNA gyrase subunit B0101
DNA gyrase subunit A0102
DNA gyrase subunit B0102
DNA topoisomerase 4 subunit A0101
DNA gyrase subunit B0101
Potassium voltage-gated channel subfamily E member 10101
DNA gyrase subunit A0101
Voltage-dependent L-type calcium channel subunit alpha-1C0101
Potassium voltage-gated channel subfamily KQT member 10101
DNA gyrase subunit B0102
DNA gyrase subunit A0102
Voltage-dependent L-type calcium channel subunit alpha-1D 0101
Voltage-dependent L-type calcium channel subunit alpha-1S0101
Protein Mdm40202
Apoptosis regulator Bcl-20112
E3 ubiquitin-protein ligase Mdm20101
Delta-type opioid receptor0011
Cytochrome P450 2C190303
E3 ubiquitin-protein ligase Mdm20101
E3 ubiquitin-protein ligase Mdm21214
Induced myeloid leukemia cell differentiation protein Mcl-10101
Peptidyl-prolyl cis-trans isomerase D0101
Mu-type opioid receptor0011
Protein arginine N-methyltransferase 50101
Protein tyrosine phosphatase type IVA 30101
Solute carrier family 22 member 30101
Coagulation factor X0101
Plasminogen0101
Urokinase-type plasminogen activator0101
Protein S100-B0112
Glyceraldehyde-3-phosphate dehydrogenase0101
Protein S100-B0011
Cytochrome P450 1A20101
Trypsin-10101
Aldo-keto reductase family 1 member B10303
Acrosin0101
Muscarinic acetylcholine receptor M20202
Muscarinic acetylcholine receptor M40202
Muscarinic acetylcholine receptor M50202
60 kDa heat shock protein, mitochondrial0101
Angiotensin-converting enzyme0202
Amiloride-sensitive amine oxidase [copper-containing]0101
Amine oxidase [flavin-containing] A0101
Diamine acetyltransferase 10101
Sodium-dependent noradrenaline transporter 0202
10 kDa heat shock protein, mitochondrial0101
Sodium-dependent dopamine transporter 0202
Glutamate receptor ionotropic, NMDA 10101
Glutamate receptor ionotropic, NMDA 2A0101
Protein tyrosine phosphatase type IVA 20101
60 kDa chaperonin 0101
Nuclear receptor subfamily 3 group C member 3 0202
10 kDa chaperonin 0101
Multidrug and toxin extrusion protein 20101
Protein tyrosine phosphatase type IVA 10101
Protein arginine N-methyltransferase 10101
Suppressor of tumorigenicity 14 protein0101
luciferase1001
Luciferin 4-monooxygenase0101
luciferase0001
Estrogen receptor0202
Progesterone receptor0203
Glucocorticoid receptor0112
Glucocorticoid receptor0011
Mineralocorticoid receptor 0213
Androgen receptor0202
Glutamine synthetase0011
Histamine H1 receptor0022
Nociceptin receptor0011
Estrogen receptor beta0202
thioredoxin glutathione reductase1001
Cell division cycle 7-related protein kinase0011
Eukaryotic translation initiation factor 5B0011
Cyclin-dependent kinase-like 50011
Sarcoplasmic/endoplasmic reticulum calcium ATPase 10101
Eukaryotic translation initiation factor 4E0011
Adenine phosphoribosyltransferase0011
ATP-dependent translocase ABCB10101
Peptidyl-prolyl cis-trans isomerase FKBP1A0101
UMP-CMP kinase 0011
Myosin-100011
Alpha-synuclein1001
Serine/threonine-protein kinase mTOR0112
Choline-phosphate cytidylyltransferase A0011
Peptidyl-prolyl cis-trans isomerase FKBP1A0213
Peptidyl-prolyl cis-trans isomerase FKBP1B0011
Protein kinase C zeta type0011
Peptidyl-prolyl cis-trans isomerase FKBP50101
Uncharacterized aarF domain-containing protein kinase 50011
Programmed cell death protein 40011
Serine/threonine-protein kinase N30011
Regulatory-associated protein of mTOR0101
Target of rapamycin complex subunit LST80101
Serine/threonine-protein kinase mTOR 0101
Thyroid hormone receptor-associated protein 30011
Chain A, MALTOPORIN0011
Chain B, MALTOPORIN0011
Carbonic anhydrase 90113
cAMP-specific 3',5'-cyclic phosphodiesterase 4A0101
cAMP-specific 3',5'-cyclic phosphodiesterase 4B0101
cAMP-specific 3',5'-cyclic phosphodiesterase 4C0101
cAMP-specific 3',5'-cyclic phosphodiesterase 4D0101
GALC protein1001
hemoglobin subunit beta1001
serine/threonine-protein kinase PLK11001
Cytochrome P450 2B10101
Endolysin0011
Chain A, CHORISMATE MUTASE0101
Chain A, TYROSYL-tRNA SYNTHETASE0011
Polyphenol oxidase 20001
Carbonic anhydrase 120001
Plasma kallikrein0001
Carbonic anhydrase 30001
Carbonic anhydrase 40001
Carbonic anhydrase 60001
Carbonic anhydrase 5A, mitochondrial0001
Glutamate receptor ionotropic, NMDA 1 0001
Carbonic anhydrase0001
Carbonic anhydrase 70001
Carbonic anhydrase0001
Glutamate receptor ionotropic, NMDA 2A 0001
Glutamate receptor ionotropic, NMDA 2B0001
Glutamate receptor ionotropic, NMDA 2C0001
SLC16A10 protein0001
Carbonic anhydrase 0001
Carbonic anhydrase-like protein, putative0001
Carbonic anhydrase0001
Carbonic anhydrase0001
Glutamate receptor ionotropic, NMDA 2D0001
Carbonic anhydrase 0001
Tubulin--tyrosine ligase0101
Glutamate receptor ionotropic, NMDA 3B0001
Monocarboxylate transporter 100001
Carbonic anhydrase 150001
Taste receptor type 2 member 140001
Glutamate receptor ionotropic, NMDA 3A0001
Carbonic anhydrase 140001
Carbonic anhydrase 5B, mitochondrial0001
Cocaine esterase0101
UDP-glucuronosyltransferase 1A90001
Cytochrome P450 2A60101
Tissue factor0101
Aldo-keto reductase family 1 member A10101
UDP-glucuronosyltransferase 1-60001
Liver carboxylesterase 10101
Aldo-keto reductase family 1 member A10101
Aldo-keto reductase family 1 member A10101
Aldo-keto reductase family 1 member B70101
Sigma non-opioid intracellular receptor 10101
NAD-dependent protein deacylase sirtuin-5, mitochondrial0101
Thymidine kinase, cytosolic0001
Adenosylhomocysteinase0101
RNA-directed RNA polymerase 0112
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]