Page last updated: 2024-09-27

Andersen Cardiodysrhythmic Periodic Paralysis

Synonyms(7)

Synonym
Andersen-Tawil Syndrome
Long QT Syndrome 7
Potassium-Sensitive Periodic Paralysis, Ventricular Ectopy, and Dysmorphic Features
Andersen Cardiodysrhythmic Periodic Paralysis
Andersen Cardiodysrythmic Periodic Paralysis
Andersen Tawil Syndrome
Periodic Paralysis, Potassium-Sensitive Cardiodysrhythmic Type

Research

Studies (38)

TimeframeStudies, This Condition (%)All Conditions %
pre-19900 (0.00)23.3326
1990's0 (0.00)12.5806
2000's9 (23.68)18.1394
2010's22 (57.89)28.8240
2020's7 (18.42)9.53
DrugIndicatedRelationship StrengthStudiesTrials
chlorine0low20
spermine0low10
phenytoin0low10
acetazolamide0low40
amiodarone0low10
atenolol0low10
bisoprolol0low10
verapamil0low20
cifenline0low10
dichlorphenamide0low10
flecainide0medium121
hydrochlorothiazide0low10
imipramine0low10
isoproterenol0low10
pinacidil0low10
potassium chloride0low10
methionine0low20
valine0low10
threonine0low10
pyridostigmine bromide0low10
hexylene glycol0low10
cesium chloride0low10
barium chloride0low10
ranolazine0low10
glycerophosphoinositol 4,5-bisphosphate0low10
cesium0low10
1-(3-sulfonatopropyl)-4-(beta)(2-(di-n-butylamino)-6-naphthylvinyl)pyridinium betaine0low10

Protein Targets (513)

ProteinPotency MeasurementsInhibition MeasurementsActivation MeasurementsDrugs
Chain A, TYROSYL-DNA PHOSPHODIESTERASE3003
Chain A, CARBONIC ANHYDRASE II0011
Chain A, CARBONIC ANHYDRASE II0011
Chain A, CARBONIC ANHYDRASE II0011
Chain A, Carbonic Anhydrase Ii0011
Chain A, Carbonic Anhydrase Ii0011
Chain A, Beta-lactamase3003
Chain A, Endochitinase0101
Chain A, Endochitinase0101
Chain A, Endochitinase0101
Chain A, Class Iii Chitinase Chia10101
Chain A, Carbonic anhydrase 130101
Chain A, Carbonic anhydrase II0101
Chain A, Carbonic anhydrase 20101
Chain A, Carbonic anhydrase 20101
Chain A, Carbonic anhydrase 20101
Chain A, Carbonic anhydrase 20101
Chain A, Carbonic anhydrase 20101
Chain A, Carbonic anhydrase 20101
Chain A, Carbonic anhydrase 20101
Chain A, Carbonic anhydrase 20101
Chain A, Carbonic anhydrase 20101
Chain A, Carbonic anhydrase0101
Chain B, Carbonic anhydrase0101
Chain A, Carbonic anhydrase 20101
Carbonic anhydrase 0002
Carbonic anhydrase 0303
thioredoxin reductase7007
GALC protein1001
GLI family zinc finger 36006
nuclear receptor subfamily 1, group I, member 36006
cytochrome P450 family 3 subfamily A polypeptide 44004
glucocorticoid receptor [Homo sapiens]6006
retinoic acid nuclear receptor alpha variant 16006
retinoid X nuclear receptor alpha3003
estrogen-related nuclear receptor alpha7007
Carbonic anhydrase 0303
Carbonic anhydrase 0202
arylsulfatase A6006
Carbonic anhydrase0202
euchromatic histone-lysine N-methyltransferase 2110011
Bloom syndrome protein isoform 13003
thyroid hormone receptor beta isoform a4004
nuclear factor erythroid 2-related factor 2 isoform 15005
geminin8008
peripheral myelin protein 225005
survival motor neuron protein isoform d3003
muscleblind-like protein 1 isoform 11001
Gamma-aminobutyric acid receptor subunit pi2215
ATP-binding cassette sub-family C member 30707
Multidrug resistance-associated protein 40707
Carbonic anhydrase0202
Solute carrier family 22 member 60202
Carbonic anhydrase 120519
Prolyl endopeptidase0202
Carbonic anhydrase-related protein 110102
Bile salt export pump012012
Glycogen phosphorylase, muscle form0202
Renin0202
Carbonic anhydrase 108114
Carbonic anhydrase 209114
Carbonic anhydrase 20202
Cytochrome P450 1A20102
Carbonic anhydrase 30519
Cathepsin B0101
Cytochrome P450 3A40304
Steryl-sulfatase0101
5-hydroxytryptamine receptor 2C0404
Polyunsaturated fatty acid 5-lipoxygenase0101
Cytochrome P450 2C80303
Cytochrome P450 2D60202
Cytochrome P450 2A60101
Cytochrome P450 2C9 0707
5-hydroxytryptamine receptor 2A0404
Androgen receptor0303
Gamma-aminobutyric acid receptor subunit beta-12215
Translocator protein0101
Gamma-aminobutyric acid receptor subunit delta2215
Gamma-aminobutyric acid receptor subunit gamma-22215
Gamma-aminobutyric acid receptor subunit alpha-52215
Gamma-aminobutyric acid receptor subunit alpha-32215
Cannabinoid receptor 10303
Arachidonate 5-lipoxygenase-activating protein0101
Cytochrome P450 2B60101
Carbonic anhydrase 407110
Carbonic anhydrase 60518
Gamma-aminobutyric acid receptor subunit gamma-12215
Gamma-aminobutyric acid receptor subunit alpha-22215
Carbonic anhydrase 5A, mitochondrial0202
Adenosine receptor A10101
Serum paraoxonase/arylesterase 10101
Dipeptidyl peptidase 40002
Gamma-aminobutyric acid receptor subunit alpha-42215
Gamma-aminobutyric acid receptor subunit gamma-32215
Endochitinase0101
Gamma-aminobutyric acid receptor subunit alpha-62215
Adenosine receptor A2a0101
5-hydroxytryptamine receptor 2B0404
Sodium-dependent serotonin transporter0303
Delta-type opioid receptor0404
Cytochrome P450 2C190203
Delta-type opioid receptor0303
Mu-type opioid receptor0404
Carbonic anhydrase 5A, mitochondrial06110
Carbonic anhydrase0303
Kappa-type opioid receptor0202
Carbonic anhydrase 70518
Carbonic anhydrase0101
D(1A) dopamine receptor3104
Corticosteroid 11-beta-dehydrogenase isozyme 10101
Carbonic anhydrase0202
D(2) dopamine receptor0303
Gamma-aminobutyric acid receptor subunit alpha-12215
Gamma-aminobutyric acid receptor subunit beta-32215
Gamma-aminobutyric acid receptor subunit beta-22215
Cholinesterase0101
Carbonic anhydrase 0101
Mu-type opioid receptor0303
Fatty-acid amide hydrolase 10101
Beta-carbonic anhydrase 10202
Carbonic anhydrase 20202
Glutamate receptor ionotropic, NMDA 2B0325
Squalene synthase0101
Neuronal acetylcholine receptor subunit alpha-70101
Carbonic anhydrase 907111
Carbonic anhydrase0101
Carbonic anhydrase, alpha family 0303
Carbonic anhydrase 0202
Carbonic anhydrase 30101
Carbonic anhydrase0203
Carbonic anhydrase0203
Carbonic anhydrase 0303
Sigma intracellular receptor 20202
Delta carbonic anhydrase0303
Sigma non-opioid intracellular receptor 10101
Renin0101
Carbonic anhydrase 0202
Endochitinase A10101
Multidrug resistance-associated protein 10101
Carbonic anhydrase 130315
GABA theta subunit2215
Canalicular multispecific organic anion transporter 10707
Carbonic anhydrase 40404
Carbonic anhydrase 150405
Acidic mammalian chitinase0101
Carbonic anhydrase 130507
Carbonic anhydrase 70101
Gamma-aminobutyric acid receptor subunit epsilon2215
Carbonic anhydrase 0101
Carbonic anhydrase 140519
Carbonic anhydrase 0101
Carbonic anhydrase 2, isoform A 0101
Carbonic anhydrase 5B, mitochondrial0519
acetylcholinesterase3003
phosphopantetheinyl transferase3003
hypoxia-inducible factor 1 alpha subunit1001
RAR-related orphan receptor gamma3003
SMAD family member 21001
ATAD5 protein, partial3003
Fumarate hydratase1001
USP1 protein, partial3003
NFKB1 protein, partial1001
PPM1D protein1001
SMAD family member 31001
TDP1 protein8008
Thrombopoietin2002
AR protein8008
caspase 7, apoptosis-related cysteine protease1001
aldehyde dehydrogenase 1 family, member A14004
hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)1001
thyroid stimulating hormone receptor1001
estrogen receptor 2 (ER beta)1001
progesterone receptor2002
EWS/FLI fusion protein5005
farnesoid X nuclear receptor1001
pregnane X nuclear receptor3003
estrogen nuclear receptor alpha8008
G5005
cytochrome P450 2D65005
polyprotein1001
peroxisome proliferator-activated receptor delta2002
peroxisome proliferator activated receptor gamma5005
caspase-31001
thyroid stimulating hormone receptor3003
v-jun sarcoma virus 17 oncogene homolog (avian)3003
Histone H2A.x2002
cytochrome P450 2D6 isoform 12002
cellular tumor antigen p53 isoform a1001
cytochrome P450 2C9 precursor4004
D(1A) dopamine receptor3003
chromobox protein homolog 16006
potassium voltage-gated channel subfamily H member 2 isoform d4004
thyroid hormone receptor beta isoform 24004
heat shock protein beta-11001
huntingtin isoform 22002
mitogen-activated protein kinase 11001
flap endonuclease 12002
serine/threonine-protein kinase mTOR isoform 13003
peptidyl-prolyl cis-trans isomerase NIMA-interacting 12002
urokinase-type plasminogen activator precursor1001
plasminogen precursor1001
urokinase plasminogen activator surface receptor precursor1001
nuclear receptor ROR-gamma isoform 13003
cytochrome P450 3A4 isoform 12002
muscarinic acetylcholine receptor M14004
lethal factor (plasmid)1001
lamin isoform A-delta10110011
Polyunsaturated fatty acid lipoxygenase ALOX15B3003
Voltage-dependent L-type calcium channel subunit alpha-1C0404
Solute carrier organic anion transporter family member 1A40101
Voltage-dependent L-type calcium channel subunit alpha-1F0606
5-hydroxytryptamine receptor 40404
Lysine-specific demethylase PHF20101
Interferon beta5005
HLA class I histocompatibility antigen, B alpha chain 5005
Thyroid hormone receptor alpha0101
Receptor tyrosine-protein kinase erbB-20101
Cellular tumor antigen p532002
Integrin beta-31001
Tyrosine-protein kinase Fyn0101
ATP-dependent translocase ABCB10202
Aldo-keto reductase family 1 member B10202
Muscarinic acetylcholine receptor M20202
Muscarinic acetylcholine receptor M40202
ATP-dependent translocase ABCB104213
Integrin alpha-IIb1001
Beta-1 adrenergic receptor0639
Muscarinic acetylcholine receptor M50202
Alpha-2A adrenergic receptor0404
Adenosine receptor A30202
Thyroid hormone receptor alpha0101
Thyroid hormone receptor beta0101
Muscarinic acetylcholine receptor M10202
Beta-3 adrenergic receptor0336
D(2) dopamine receptor0505
Alpha-1B adrenergic receptor0606
Lethal factor0101
Alpha-2B adrenergic receptor0202
Thyroid hormone receptor beta0101
Muscarinic acetylcholine receptor M30202
ATP-dependent translocase ABCB10203
Substance-K receptor0202
D(1A) dopamine receptor0303
D(4) dopamine receptor0303
Carnitine O-palmitoyltransferase 2, mitochondrial0101
Sodium-dependent noradrenaline transporter 0404
Histamine H2 receptor0404
Endothelin-1 receptor0202
5-hydroxytryptamine receptor 2A0606
5-hydroxytryptamine receptor 2C0505
Lysine-specific demethylase 5A0101
B2 bradykinin receptor0202
Sodium-dependent serotonin transporter0606
Melanocortin receptor 40202
C-8 sterol isomerase0101
Melanocortin receptor 50202
Mu-type opioid receptor0202
D(3) dopamine receptor0505
Sodium channel protein type 1 subunit alpha0404
Sodium channel protein type 4 subunit alpha0405
Squalene synthase0101
Delta-type opioid receptor0202
Kappa-type opioid receptor0202
5-hydroxytryptamine receptor 2B0404
C-C chemokine receptor type 20202
Melanocortin receptor 30202
Alpha-1A adrenergic receptor0606
Histamine H2 receptor6118
5-hydroxytryptamine receptor 60303
Carnitine O-palmitoyltransferase 1, liver isoform0101
C-C chemokine receptor type 40202
Spike glycoprotein9009
Sodium channel protein type 7 subunit alpha0303
Voltage-dependent L-type calcium channel subunit alpha-1D 0606
Sodium-dependent dopamine transporter 0303
Potassium voltage-gated channel subfamily H member 20707
Voltage-dependent L-type calcium channel subunit alpha-1S0606
Voltage-dependent L-type calcium channel subunit alpha-1C0606
Sodium channel protein type 5 subunit alpha0707
Squalene monooxygenase0101
3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase0101
Sodium channel protein type 9 subunit alpha0404
Lysine-specific demethylase 7A0101
Carnitine O-palmitoyltransferase 1, muscle isoform0101
Inositol hexakisphosphate kinase 15005
Sodium channel protein type 2 subunit alpha0404
Ataxin-24004
Sigma non-opioid intracellular receptor 10202
NAD-dependent protein deacetylase sirtuin-3, mitochondrial0011
Sodium channel protein type 3 subunit alpha0404
Sodium channel protein type 11 subunit alpha0303
Histone lysine demethylase PHF80101
Sodium channel protein type 8 subunit alpha0303
Sodium channel protein type 10 subunit alpha0303
cytochrome P450 2C9, partial5005
ATP-dependent phosphofructokinase6006
regulator of G-protein signaling 45005
Beta-1 adrenergic receptor 0023
DNA polymerase iota isoform a (long)1001
Fatty acid-binding protein, liver0101
Urease0101
Beta-2 adrenergic receptor05410
5-hydroxytryptamine receptor 1A0516
Alpha-1D adrenergic receptor0112
Alpha-1A adrenergic receptor0112
Alpha-1B adrenergic receptor0112
TAR DNA-binding protein 431001
Beta-2 adrenergic receptor0033
DNA polymerase kappa isoform 11001
Beta-1 adrenergic receptor0213
GLS protein4004
atrial natriuretic peptide receptor 2 precursor2002
Chain A, MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASE4004
Chain A, Carbonic anhydrase 20101
Chain A, Carbonic anhydrase 20101
Chain A, Carbonic anhydrase 20101
cystic fibrosis transmembrane conductance regulator ATP-binding cassette sub-family C member 70001
Potassium voltage-gated channel subfamily A member 50101
Cytochrome P450 2J20404
Potassium voltage-gated channel subfamily A member 10101
Potassium voltage-gated channel subfamily D member 20101
Hsf1 protein0011
peripheral myelin protein 22 isoform 13003
Voltage-dependent calcium channel gamma-2 subunit1001
Albumin0112
Glutamate receptor 21001
Guanine nucleotide-binding protein G1001
Microtubule-associated protein tau3003
Snq2p0001
activating transcription factor 64004
nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105), isoform CRA_a1001
Solute carrier family 22 member 20101
Solute carrier family 22 member 1 0303
Sodium-dependent noradrenaline transporter0101
Solute carrier family 22 member 30101
Major prion protein0011
Prostaglandin G/H synthase 10101
5-hydroxytryptamine receptor 1A0101
Muscarinic acetylcholine receptor M50101
Sphingomyelin phosphodiesterase0101
D0101
D(3) dopamine receptor0101
Alpha-2B adrenergic receptor0404
Alpha-2C adrenergic receptor0404
UDP-glucuronosyltransferase 1A40001
Alpha-2A adrenergic receptor0404
Alpha-1D adrenergic receptor0404
Sodium-dependent dopamine transporter0101
D(1B) dopamine receptor0101
5-hydroxytryptamine receptor 1B0303
5-hydroxytryptamine receptor 1D0101
D(4) dopamine receptor0101
5-hydroxytryptamine receptor 1F0101
5-hydroxytryptamine receptor 60101
Histamine H1 receptor0101
5-hydroxytryptamine receptor 7 0101
Pleiotropic ABC efflux transporter of multiple drugs0102
5-hydroxytryptamine receptor 2C 0101
5-hydroxytryptamine receptor 70101
5-hydroxytryptamine receptor 5A0101
5-hydroxytryptamine receptor 5B0101
Histamine H1 receptor0202
Glutamate receptor ionotropic, NMDA 1 0224
UDP-glucuronosyltransferase 1A30001
5-hydroxytryptamine receptor 3A0101
5-hydroxytryptamine receptor 70202
D(2) dopamine receptor0101
Glutamate receptor ionotropic, NMDA 2A 0213
Glutamate receptor ionotropic, NMDA 2C0213
Voltage-dependent N-type calcium channel subunit alpha-1B0101
Envelope glycoprotein0011
Sodium-dependent serotonin transporter0101
Sodium-dependent dopamine transporter0101
Glutamate receptor ionotropic, NMDA 2D0213
5-hydroxytryptamine receptor 4 0101
Solute carrier family 22 member 10101
Multidrug and toxin extrusion protein 20101
Glutamate receptor ionotropic, NMDA 3B0213
Multidrug and toxin extrusion protein 10101
5-hydroxytryptamine receptor 3B0101
Sigma non-opioid intracellular receptor 10101
Solute carrier family 22 member 20101
Glutamate receptor ionotropic, NMDA 3A0213
Transporter0202
glp-1 receptor, partial3003
NPYLR7B0011
beta-2 adrenergic receptor1001
hexokinase-4 isoform 11001
vitamin D3 receptor isoform VDRA1001
glucokinase regulatory protein1001
Bile salt export pump0303
Beta-2 adrenergic receptor0213
Polyunsaturated fatty acid lipoxygenase ALOX150101
Beta-1 adrenergic receptor0214
Beta-2 adrenergic receptor0011
Beta-adrenergic receptor kinase 10011
Beta-3 adrenergic receptor0011
Beta-3 adrenergic receptor0112
Vasopressin V1a receptor0011
Beta-2 adrenergic receptor0101
Taste receptor type 2 member 380011
Taste receptor type 2 member 390011
Taste receptor type 2 member 400011
Taste receptor type 2 member 410011
Taste receptor type 2 member 430011
Taste receptor type 2 member 310022
Taste receptor type 2 member 450011
Taste receptor type 2 member 460011
Taste receptor type 2 member 300011
Taste receptor type 2 member 190011
Taste receptor type 2 member 200011
Taste receptor type 2 member 500011
Taste receptor type 2 member 600022
Oxytocin receptor0011
Beta-2 adrenergic receptor 0112
Taste receptor type 2 member 420011
Taste receptor type 2 member 160011
Taste receptor type 2 member 140022
Taste receptor type 2 member 130022
Taste receptor type 2 member 100011
Taste receptor type 2 member 90022
Taste receptor type 2 member 80011
Taste receptor type 2 member 70011
Taste receptor type 2 member 50011
Taste receptor type 2 member 40022
Taste receptor type 2 member 30011
Taste receptor type 2 member 10011
2,3-bisphosphoglycerate-independent phosphoglycerate mutase1001
Chain A, Methionyl-tRNA synthetase0011
Chain A, Methionyl-tRNA synthetase0011
Chain A, Aminopeptidase0101
Chain A, Methionine aminopeptidase0101
S-ribosylhomocysteine lyase0101
Adenylate cyclase type 50001
S-adenosylmethionine synthase isoform type-10001
S-adenosylmethionine synthase isoform type-20001
Fatty acid synthase0101
Large neutral amino acids transporter small subunit 10202
Chain A, Putative fructose-1,6-bisphosphate aldolase1001
Gamma-aminobutyric acid 0101
endonuclease IV2002
vitamin D (1,25- dihydroxyvitamin D3) receptor1001
cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a1001
atrial natriuretic peptide receptor 1 precursor1001
parathyroid hormone/parathyroid hormone-related peptide receptor precursor2002
transcriptional regulator ERG isoform 31001
Gamma-aminobutyric acid receptor subunit pi0101
Gamma-aminobutyric acid receptor subunit delta0101
Dihydrofolate reductase 0101
Sodium channel protein type 2 subunit alpha0101
Gamma-aminobutyric acid receptor subunit alpha-10101
Aldo-keto reductase family 1 member B10101
Gamma-aminobutyric acid receptor subunit alpha-60101
Gamma-aminobutyric acid receptor subunit beta-10101
Gamma-aminobutyric acid receptor subunit gamma-20101
Gamma-aminobutyric acid receptor subunit gamma-20101
Gamma-aminobutyric acid receptor subunit delta0101
Gamma-aminobutyric acid receptor subunit alpha-20101
Gamma-aminobutyric acid receptor subunit alpha-30101
Gamma-aminobutyric acid receptor subunit gamma-30101
Gamma-aminobutyric acid receptor subunit beta-30101
Gamma-aminobutyric acid receptor subunit alpha-50101
Gamma-aminobutyric acid receptor subunit alpha-30101
Gamma-aminobutyric acid receptor subunit alpha-20101
Gamma-aminobutyric acid receptor subunit beta-20101
Gamma-aminobutyric acid receptor subunit alpha-40101
Gamma-aminobutyric acid receptor subunit beta-10101
Gamma-aminobutyric acid receptor subunit alpha-10101
Gamma-aminobutyric acid receptor subunit beta-30101
Gamma-aminobutyric acid receptor subunit epsilon0101
Inositol monophosphatase 11001
Gamma-aminobutyric acid receptor subunit alpha-60101
Gamma-aminobutyric acid receptor subunit alpha-50101
Gamma-aminobutyric acid receptor subunit gamma-10101
Gamma-aminobutyric acid receptor subunit pi0101
Gamma-aminobutyric acid receptor subunit gamma-30101
Gamma-aminobutyric acid receptor subunit alpha-40101
Gamma-aminobutyric acid receptor subunit theta0101
Gamma-aminobutyric acid receptor subunit gamma-10101
Gamma-aminobutyric acid receptor subunit theta0101
alpha-galactosidase2002
nuclear factor erythroid 2-related factor 2 isoform 21001
Vpr1001
M-phase phosphoprotein 82002
neuropeptide S receptor isoform A1001
ATP-binding cassette sub-family C member 90011
Rap guanine nucleotide exchange factor 41001
Sodium/potassium/calcium exchanger 40112
Sodium/potassium/calcium exchanger 20112
Acetylcholinesterase0101
Voltage-gated sodium channel Nav1.5 cardiac isoform 0101
Chain A, HADH2 protein1001
Chain B, HADH2 protein1001
Chain A, ATP-DEPENDENT DNA HELICASE Q11001
dopamine D1 receptor1001
15-lipoxygenase, partial1001
cytochrome P450 2C19 precursor1001
DNA topoisomerase 2-alpha0101
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A 0101
Caspase-20011
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B0101
Glutamate receptor ionotropic, NMDA 2B0011
Chain A, Arginase 10101
glucocerebrosidase1001
lysosomal alpha-glucosidase preproprotein1001
Glycoprotein0101
Muscarinic acetylcholine receptor M20011
Catechol O-methyltransferase0101
Potassium voltage-gated channel subfamily A member 30101
Multidrug resistance-associated protein 1 0214
Chloroquine resistance transporter0101
Broad substrate specificity ATP-binding cassette transporter ABCG20112
Solute carrier organic anion transporter family member 1B10202
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]