Amniotic Band Syndrome

A disorder present in the newborn infant in which constriction rings or bands, causing soft tissue depressions, encircle digits, extremities, or limbs and sometimes the neck, thorax, or abdomen. They may be associated with intrauterine amputations.

Synonym
Annular Grooves
Amniotic Bands
Amniotic Band Syndrome
Streeter Syndrome
Amputation, Intrauterine
Ring Constrictions, Intrauterine

Excerpt	Reference
"Amniotic band syndrome is a sporadic condition that may result in constriction bands, amputation and multiple craniofacial, visceral and body wall defects."	( Briceño, F; Navarro, H; Ronderos-Dumit, D; Sanchez, N, 2006)
"Amniotic band syndrome is an uncommon congenital pathological condition that may lead to malformations and foetal-infant death."	( Agostini, E; Buccoliero, AM; Castiglione, F; Fiorini, P; Garbini, F; Lapi, E; Moncini, D; Taddei, GL, 2011)
"Pseudoamniotic band syndrome is a rare iatrogenic complication of twin-to-twin transfusion syndrome treated with foetoscopic procedures."	( Borman, H; Çöloğlu, H; Çöloğlu, Ö; Özkan, B; Uysal, AÇ; Yalçınkaya, C, 2014)
"The etiology of the amniotic band syndrome is unknown, and has been subject of debate since the time of Hippocrates."	( Bobadilla-Sandoval, N; Flisser, A; Romero-Valdovinos, M; Vadillo-Ortega, F, 2014)

Excerpt	Reference
"Patients with amniotic band syndrome affecting the limbs were evaluated in the period between 1997 and 2007."	( Daya, M; Makakole, M, 2011)

Excerpt	Reference
"Pseudoamniotic band syndrome is a rare iatrogenic complication of twin-to-twin transfusion syndrome treated with foetoscopic procedures."	( Borman, H; Çöloğlu, H; Çöloğlu, Ö; Özkan, B; Uysal, AÇ; Yalçınkaya, C, 2014)

Timeframe	Studies, This Condition (%)	All Conditions %
pre-1990	25 (28.74)	23.3326
1990's	14 (16.09)	12.5806
2000's	24 (27.59)	18.1394
2010's	19 (21.84)	28.8240
2020's	5 (5.75)	9.53

Drug	Relationship Strength	Studies
salicylic acid	low	7
hydrogen	low	1
acetaminophen	low	1
alendronate	low	1
valproic acid	low	1
2-propanol	low	2
khellin	low	1
methadone	low	1
propofol	low	1
succinylcholine	low	1
thalidomide	low	1
propiconazole	low	3
mifepristone	low	1
oxytocin	low	1
inositol 3-phosphate	low	1
isotretinoin	low	1
misoprostol	low	3
phenylephrine hydrochloride	low	2
morphine	low	1
cellulose	low	1
transforming growth factor beta	low	2
vitamin b 12	low	1
thromboplastin	low	1
acyclovir	low	1
eye	low	3

Protein Targets (486)

Protein	Potency Measurements	Inhibition Measurements	Activation Measurements	Drugs
hypoxia-inducible factor 1 alpha subunit	2	0	0	2
RAR-related orphan receptor gamma	7	0	0	7
GLI family zinc finger 3	8	0	0	8
AR protein	7	0	0	7
aldehyde dehydrogenase 1 family, member A1	7	0	0	7
retinoic acid nuclear receptor alpha variant 1	7	0	0	7
retinoid X nuclear receptor alpha	7	0	0	7
estrogen nuclear receptor alpha	12	0	0	12
peroxisome proliferator-activated receptor delta	4	0	0	4
cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a	7	0	0	7
activating transcription factor 6	5	0	0	5
v-jun sarcoma virus 17 oncogene homolog (avian)	2	0	0	2
Histone H2A.x	4	0	0	4
thyroid hormone receptor beta isoform a	5	0	0	5
heat shock protein beta-1	4	0	0	4
nuclear factor erythroid 2-related factor 2 isoform 1	6	0	0	6
lamin isoform A-delta10	6	0	0	6
Voltage-dependent calcium channel gamma-2 subunit	5	0	0	5
Glutamate receptor 2	5	0	0	5
ATAD5 protein, partial	4	0	0	4
GLS protein	4	0	0	4
Microtubule-associated protein tau	3	0	0	3
Smad3	2	0	0	2
thyroid stimulating hormone receptor	3	0	0	3
nuclear receptor subfamily 1, group I, member 3	6	0	0	6
progesterone receptor	4	0	0	4
EWS/FLI fusion protein	4	0	0	4
estrogen-related nuclear receptor alpha	7	0	0	7
peroxisome proliferator activated receptor gamma	7	0	0	7
aryl hydrocarbon receptor	3	0	0	3
chromobox protein homolog 1	4	0	0	4
thyroid hormone receptor beta isoform 2	6	0	0	6
peripheral myelin protein 22	6	0	0	6
cytochrome P450 3A4 isoform 1	3	0	0	3
Gamma-aminobutyric acid receptor subunit pi	3	1	1	5
ATP-binding cassette sub-family C member 3	0	5	0	5
Multidrug resistance-associated protein 4	0	5	0	5
Solute carrier family 22 member 6	0	2	0	3
Carbonic anhydrase 12	0	2	0	2
UDP-glucuronosyltransferase 1A9	0	0	0	3
Bile salt export pump	0	4	0	4
Bile salt export pump	0	9	0	9
Cytochrome P450 2B1	0	0	0	1
Cytochrome P450 1A1	0	0	0	1
Carbonic anhydrase 1	0	4	0	4
Carbonic anhydrase 2	0	4	0	4
Myoglobin	0	1	0	1
Cytochrome P450 1A1	0	2	1	4
Cytochrome P450 1A2	0	2	0	3
Prostaglandin G/H synthase 1	0	3	0	3
Carbonic anhydrase 3	0	2	0	2
Cytochrome P450 3A4	0	7	1	8
Cytochrome P450 2D6	0	2	0	2
Cytochrome P450 2C9	0	4	0	4
Polyunsaturated fatty acid lipoxygenase ALOX15	0	3	0	3
Gamma-aminobutyric acid receptor subunit beta-1	3	1	1	5
Sulfotransferase 1A1	0	0	0	1
Gamma-aminobutyric acid receptor subunit delta	3	1	1	5
Gamma-aminobutyric acid receptor subunit gamma-2	3	1	1	5
UDP-glucuronosyltransferase 1-6	0	0	0	2
Gamma-aminobutyric acid receptor subunit alpha-5	3	1	1	5
Gamma-aminobutyric acid receptor subunit alpha-3	3	1	1	5
Arachidonate 5-lipoxygenase-activating protein	0	1	0	1
UDP-glucuronosyltransferase 1A1	0	0	0	1
Carbonic anhydrase 4	0	2	0	2
Prostaglandin G/H synthase 1	0	4	0	4
Carbonic anhydrase 6	0	2	0	2
Gamma-aminobutyric acid receptor subunit gamma-1	3	1	1	5
Gamma-aminobutyric acid receptor subunit alpha-2	3	1	1	5
Gamma-aminobutyric acid receptor subunit alpha-4	3	1	1	5
Gamma-aminobutyric acid receptor subunit gamma-3	3	1	1	5
Gamma-aminobutyric acid receptor subunit alpha-6	3	1	1	5
Carbonic anhydrase 5A, mitochondrial	0	2	0	2
Prostaglandin G/H synthase 2	0	1	0	2
Carbonic anhydrase 7	0	2	0	2
Nuclear receptor ROR-gamma	2	0	0	2
Cytochrome P450 2J2	0	2	0	2
Gamma-aminobutyric acid receptor subunit alpha-1	3	1	1	5
Gamma-aminobutyric acid receptor subunit beta-3	3	1	1	5
Gamma-aminobutyric acid receptor subunit beta-2	3	1	1	5
Carbonic anhydrase 9	0	2	0	2
GABA theta subunit	3	1	1	5
Canalicular multispecific organic anion transporter 1	0	5	0	5
Carbonic anhydrase 15	0	2	0	2
Carbonic anhydrase 13	0	2	0	2
Gamma-aminobutyric acid receptor subunit epsilon	3	1	1	5
Carbonic anhydrase 14	0	2	0	2
Carbonic anhydrase 5B, mitochondrial	0	2	0	2
toxin B	0	0	0	1
Chain E, Purine nucleoside phosphorylase	0	1	0	1
Chain A, HADH2 protein	1	0	0	1
Chain B, HADH2 protein	1	0	0	1
Chain A, ATP-DEPENDENT DNA HELICASE Q1	1	0	0	1
Chain A, Ferritin light chain	6	0	0	6
Thymidine kinase	0	1	0	1
thioredoxin reductase	6	0	0	6
phosphopantetheinyl transferase	2	0	0	2
TDP1 protein	9	0	0	9
arylsulfatase A	2	0	0	2
euchromatic histone-lysine N-methyltransferase 2	8	0	0	8
Bloom syndrome protein isoform 1	5	0	0	5
hemoglobin subunit beta	1	0	0	1
atrial natriuretic peptide receptor 1 precursor	1	0	0	1
ubiquitin carboxyl-terminal hydrolase 2 isoform a	1	0	0	1
Solute carrier family 22 member 1	0	1	0	2
Purine nucleoside phosphorylase	0	1	0	1
Thymidine kinase, cytosolic	0	0	0	1
POU domain, class 2, transcription factor 2	0	0	0	1
Disintegrin and metalloproteinase domain-containing protein 17	1	0	0	1
Purine nucleoside phosphorylase	0	0	1	1
Solute carrier family 22 member 6	0	1	0	2
Thymidine kinase	0	1	0	1
Solute carrier family 22 member 8	0	1	0	2
Thymidine kinase	0	1	0	1
Chain A, farnesyl pyrophosphate synthase	0	1	0	1
Geranylgeranyl pyrophosphate synthase	0	1	0	1
Farnesyl pyrophosphate synthase	0	2	0	2
Acetylcholinesterase	0	2	0	2
Hypoxanthine-guanine phosphoribosyltransferase	0	1	0	1
Farnesyl pyrophosphate synthase	0	1	0	1
Farnesyl pyrophosphate synthase	0	1	0	1
Chain A, CHIMERA OF IG KAPPA CHAIN: HUMAN CONSTANT REGION AND MOUSE VARIABLE REGION	0	0	1	1
Chain B, CHIMERA OF IG GAMMA-1 CHAIN: HUMAN CONSTANT REGION AND MOUSE VARIABLE REGION	0	0	1	1
Chain H, Fab M82G2, Heavy chain	0	0	1	1
Chain L, Fab M82G2, Light chain	0	0	1	1
Chain H, Fab M82g2, Heavy Chain	0	0	1	1
Chain L, Fab M82g2, Light Chain	0	0	1	1
Gamma-aminobutyric acid receptor subunit pi	0	1	0	1
Gamma-aminobutyric acid receptor subunit delta	0	1	0	1
Amyloid-beta precursor protein	0	1	0	1
Fatty acid-binding protein, heart	0	1	0	1
Muscarinic acetylcholine receptor M2	0	1	0	1
Muscarinic acetylcholine receptor M1	0	2	0	2
5-hydroxytryptamine receptor 2C	0	2	0	2
Tryptophan 5-hydroxylase 1	0	1	0	1
5-hydroxytryptamine receptor 2A	0	2	0	2
Gamma-aminobutyric acid receptor subunit alpha-1	0	2	1	3
Gamma-aminobutyric acid receptor subunit beta-1	0	1	1	2
Gamma-aminobutyric acid receptor subunit gamma-2	0	2	1	3
D	0	1	0	1
5-hydroxytryptamine receptor 1A	0	2	0	2
Alpha-2B adrenergic receptor	0	1	0	1
Alpha-2C adrenergic receptor	0	1	0	1
Alpha-2A adrenergic receptor	0	1	0	1
Liver carboxylesterase 1	0	1	0	2
Sodium-dependent noradrenaline transporter	0	4	0	4
Sodium-dependent dopamine transporter	0	2	0	2
cAMP-specific 3',5'-cyclic phosphodiesterase 4A	0	2	0	2
Gamma-aminobutyric acid receptor subunit beta-3	0	2	1	3
5-hydroxytryptamine receptor 1B	0	1	0	1
5-hydroxytryptamine receptor 1D	0	1	0	1
5-hydroxytryptamine receptor 1F	0	1	0	1
5-hydroxytryptamine receptor 2B	0	2	0	2
5-hydroxytryptamine receptor 6	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-5	0	1	1	2
Sodium-dependent serotonin transporter	0	2	0	2
Sodium-dependent serotonin transporter	0	3	0	4
5-hydroxytryptamine receptor 7	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-3	0	1	1	2
5-hydroxytryptamine receptor 5A	0	1	0	1
5-hydroxytryptamine receptor 5B	0	1	0	1
Glutamate receptor ionotropic, NMDA 1	0	1	0	1
5-hydroxytryptamine receptor 3A	0	1	0	1
Lysosomal Pro-X carboxypeptidase	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-2	0	1	1	2
Gamma-aminobutyric acid receptor subunit beta-2	0	1	1	2
Gamma-aminobutyric acid receptor subunit alpha-4	0	1	1	2
D(2) dopamine receptor	0	1	0	1
Gamma-aminobutyric acid receptor subunit epsilon	0	1	0	1
Glutamate receptor ionotropic, NMDA 2A	0	1	0	1
Glutamate receptor ionotropic, NMDA 2B	0	1	0	1
Glutamate receptor ionotropic, NMDA 2C	0	1	0	1
Sodium-dependent dopamine transporter	0	2	0	2
cAMP-specific 3',5'-cyclic phosphodiesterase 4B	0	2	0	2
cAMP-specific 3',5'-cyclic phosphodiesterase 4D	0	2	0	2
Potassium voltage-gated channel subfamily H member 2	0	4	0	4
Leukotriene B4 receptor 1	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-6	0	1	1	2
Sodium-dependent dopamine transporter	0	2	0	2
Glutamate receptor ionotropic, NMDA 2D	0	1	0	1
5-hydroxytryptamine receptor 4	0	1	0	1
Gamma-aminobutyric acid receptor subunit gamma-1	0	1	0	1
Glutamate receptor ionotropic, NMDA 3B	0	1	0	1
Sigma non-opioid intracellular receptor 1	0	5	0	5
Gamma-aminobutyric acid receptor subunit gamma-3	0	1	0	1
5-hydroxytryptamine receptor 3B	0	1	0	1
Leukotriene B4 receptor 2	0	1	0	1
Glutamate receptor ionotropic, NMDA 3A	0	1	0	1
Gamma-aminobutyric acid receptor subunit theta	0	1	0	1
Transporter	0	2	0	2
Chain A, Cruzipain	3	0	0	3
Luciferase	2	0	0	2
estrogen receptor 2 (ER beta)	3	0	0	3
regulator of G-protein signaling 4	2	0	0	2
glucocorticoid receptor [Homo sapiens]	6	0	0	6
farnesoid X nuclear receptor	6	0	0	6
pregnane X nuclear receptor	4	0	0	4
67.9K protein	1	0	0	1
Parkin	1	0	0	1
vitamin D (1,25- dihydroxyvitamin D3) receptor	2	0	0	2
thyroid stimulating hormone receptor	2	0	0	2
nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105), isoform CRA_a	2	0	0	2
Caspase-7	1	0	0	1
peripheral myelin protein 22 isoform 1	1	0	0	1
vitamin D3 receptor isoform VDRA	4	0	0	4
parathyroid hormone/parathyroid hormone-related peptide receptor precursor	1	0	0	1
potassium voltage-gated channel subfamily H member 2 isoform d	3	0	0	3
caspase-3	1	0	0	1
serine/threonine-protein kinase mTOR isoform 1	2	0	0	2
serine/threonine-protein kinase PLK1	1	0	0	1
peptidyl-prolyl cis-trans isomerase NIMA-interacting 1	1	0	0	1
DNA polymerase eta isoform 1	1	0	0	1
DNA polymerase iota isoform a (long)	4	0	0	4
geminin	7	0	0	7
Ornithine decarboxylase	0	0	0	1
Cellular tumor antigen p53	9	0	0	9
Adenosine receptor A3	0	2	0	2
Retinoic acid receptor alpha	0	1	0	1
Alpha-1B adrenergic receptor	0	2	0	2
Alpha-2B adrenergic receptor	0	4	0	4
Retinoic acid receptor gamma	0	1	0	1
Retinoic acid receptor beta	0	1	0	1
Cellular retinoic acid-binding protein 2	0	0	1	1
Mitogen-activated protein kinase 1	0	1	0	1
Retinoic acid receptor RXR-alpha	0	1	0	1
Retinoic acid receptor RXR-beta	0	1	0	1
Retinoic acid receptor RXR-gamma	0	1	0	1
Cellular retinoic acid-binding protein 1	0	1	0	1
5-hydroxytryptamine receptor 2B	0	4	0	4
Alpha-1A adrenergic receptor	0	2	0	2
Cellular retinoic acid-binding protein 1	0	0	1	1
Mitogen-activated protein kinase 14	0	2	0	2
Rap guanine nucleotide exchange factor 4	1	0	0	1
Olfactory receptor 51E2	0	1	0	1
Chain A, MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASE	3	0	0	3
glp-1 receptor, partial	4	0	0	4
USP1 protein, partial	4	0	0	4
GALC protein	2	0	0	2
cytochrome P450 family 3 subfamily A polypeptide 4	5	0	0	5
G	4	0	0	4
cytochrome P450 2D6	4	0	0	4
cytochrome P450 2D6 isoform 1	1	0	0	1
cytochrome P450 2C19 precursor	1	0	0	1
15-hydroxyprostaglandin dehydrogenase [NAD(+)] isoform 1	3	0	0	3
importin subunit beta-1 isoform 1	1	0	0	1
mitogen-activated protein kinase 1	1	0	0	1
snurportin-1	1	0	0	1
GTP-binding nuclear protein Ran isoform 1	1	0	0	1
survival motor neuron protein isoform d	3	0	0	3
histone acetyltransferase KAT2A isoform 1	3	0	0	3
Interferon beta	4	0	0	4
HLA class I histocompatibility antigen, B alpha chain	4	0	0	4
Cytochrome P450 2C19	0	1	0	1
Cytochrome P450 1B1	0	1	0	1
Inositol hexakisphosphate kinase 1	4	0	0	4
cytochrome P450 2C9, partial	4	0	0	4
Voltage-dependent L-type calcium channel subunit alpha-1F	0	1	0	1
ATP-dependent translocase ABCB1	0	2	0	2
D(2) dopamine receptor	0	1	0	1
Cytochrome P450 2B6	0	1	0	1
D(4) dopamine receptor	0	1	0	1
Mu-type opioid receptor	0	6	1	8
D(3) dopamine receptor	0	1	0	1
Delta-type opioid receptor	0	3	1	5
Kappa-type opioid receptor	0	5	1	7
Voltage-dependent L-type calcium channel subunit alpha-1D	0	1	0	1
Voltage-dependent L-type calcium channel subunit alpha-1S	0	1	0	1
Voltage-dependent L-type calcium channel subunit alpha-1C	0	1	0	1
Mas-related G-protein coupled receptor member X2	0	0	2	2
Aldehyde oxidase 1	0	1	0	1
Chain A, TYROSYL-DNA PHOSPHODIESTERASE	2	0	0	2
Chain A, Beta-lactamase	2	0	0	2
Chain A, JmjC domain-containing histone demethylation protein 3A	1	0	0	1
Chain A, PROGESTERONE RECEPTOR	0	1	0	1
Glucocorticoid receptor	0	1	0	1
dopamine D1 receptor	1	0	0	1
pregnane X receptor	3	0	0	3
SMAD family member 2	2	0	0	2
Fumarate hydratase	1	0	0	1
SMAD family member 3	2	0	0	2
apical membrane antigen 1, AMA1	1	0	0	1
hypothetical protein, conserved	1	0	0	1
nonstructural protein 1	2	0	0	2
polyprotein	1	0	0	1
bromodomain adjacent to zinc finger domain 2B	1	0	0	1
nuclear receptor subfamily 1, group I, member 2	1	0	0	1
D(1A) dopamine receptor	3	0	0	3
nuclear factor erythroid 2-related factor 2 isoform 2	1	0	0	1
huntingtin isoform 2	1	0	0	1
atrial natriuretic peptide receptor 2 precursor	1	0	0	1
urokinase-type plasminogen activator precursor	1	0	0	1
plasminogen precursor	1	0	0	1
urokinase plasminogen activator surface receptor precursor	1	0	0	1
nuclear receptor ROR-gamma isoform 1	4	0	0	4
M-phase phosphoprotein 8	1	0	0	1
neuropeptide S receptor isoform A	2	0	0	2
Estrogen receptor	1	2	1	4
Glucocorticoid receptor	1	2	2	7
Tyrosine-protein kinase Fyn	0	1	0	1
Progesterone receptor	0	2	1	5
Tegument protein VP16	0	0	1	1
Glucocorticoid receptor	0	1	1	3
Glucocorticoid receptor	0	1	0	1
Glycine receptor subunit alpha-1	0	2	0	2
Mineralocorticoid receptor	1	2	1	5
Coagulation factor VII	0	1	0	1
Androgen receptor	1	2	1	4
Cytochrome P450 2C8	0	1	0	1
Thyroid hormone receptor alpha	0	1	0	1
Thyroid hormone receptor beta	0	1	0	1
Steroid 17-alpha-hydroxylase/17,20 lyase	0	1	0	1
Tissue factor	0	2	0	2
Androgen receptor	0	2	0	2
Glycine receptor subunit beta	0	2	0	2
ATP-dependent translocase ABCB1	0	1	1	2
Glycine receptor subunit alpha-2	0	2	0	2
Glycine receptor subunit alpha-3	0	2	0	2
Adenosine receptor A1	0	0	1	1
Adenosine receptor A2a	0	0	1	1
Substance-P receptor	0	1	0	1
D(1A) dopamine receptor	1	0	0	1
Guanine nucleotide-binding protein G	2	0	0	2
Progesterone receptor	0	0	1	1
Estrogen receptor beta	1	2	1	4
ATPase family AAA domain-containing protein 5	5	0	0	5
Ataxin-2	5	0	0	5
Glucocorticoid receptor	0	1	0	1
ATP-dependent phosphofructokinase	1	0	0	1
thioredoxin glutathione reductase	1	0	0	1
DNA polymerase beta	1	0	0	1
Opioid receptor, delta 1b	0	1	0	1
Acetylcholinesterase	0	1	0	1
Opioid receptor homologue	0	1	0	1
ATP-dependent translocase ABCB1	0	1	0	1
Acyl-CoA desaturase 1	0	1	0	1
Muscarinic acetylcholine receptor M3	0	1	0	1
Muscarinic acetylcholine receptor M4	0	1	0	1
Muscarinic acetylcholine receptor M5	0	1	0	1
Alpha-2A adrenergic receptor	0	0	1	1
Muscarinic acetylcholine receptor M2	0	1	0	1
Translocator protein	0	0	1	1
Histidine decarboxylase	0	0	1	1
Proteinase-activated receptor 1	0	1	1	2
Delta-type opioid receptor	0	1	0	2
Delta-type opioid receptor	0	2	1	4
Kappa-type opioid receptor	0	2	1	4
Mu-type opioid receptor	0	2	1	6
Kappa-type opioid receptor	0	2	1	4
UDP-glucuronosyltransferase 1A3	0	0	0	1
Kappa-type opioid receptor	0	2	0	2
Mu-type opioid receptor	0	2	1	5
Nociceptin receptor	0	1	0	1
5-hydroxytryptamine receptor 7	0	1	0	1
Mu-type opioid receptor	0	1	0	1
Mu-type opioid receptor	0	2	0	2
Beta-2 adrenergic receptor	0	1	0	1
Mu-type opioid receptor	0	1	0	1
Sodium channel protein type 1 subunit alpha	0	1	0	1
Sodium channel protein type 2 subunit alpha	0	1	0	1
Sodium channel protein type 3 subunit alpha	0	1	0	1
Vasopressin V2 receptor	0	1	1	2
Oxytocin receptor	0	2	2	4
Vasopressin V1a receptor	0	1	0	1
Vasopressin V1a receptor	0	2	1	3
Vasopressin V1b receptor	0	1	1	2
Vasopressin V1b receptor	0	1	0	1
Oxytocin receptor	0	1	0	1
Oxytocin receptor	0	0	1	1
Vasopressin V2 receptor	0	1	0	1
Chain A, 2-oxoglutarate Oxygenase	2	0	0	2
hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)	2	0	0	2
IDH1	1	0	0	1
beta-2 adrenergic receptor	1	0	0	1
lysosomal alpha-glucosidase preproprotein	1	0	0	1
mu-type opioid receptor isoform MOR-1	0	0	1	1
Vpr	1	0	0	1
5-hydroxytryptamine receptor 2A	0	0	1	1
Neuronal acetylcholine receptor subunit alpha-4	1	0	0	1
Neuronal acetylcholine receptor subunit beta-2	1	0	0	1
Spike glycoprotein	2	0	0	2
heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)	1	0	0	1
heat shock protein HSP 90-alpha isoform 2	0	0	0	1
Polyunsaturated fatty acid lipoxygenase ALOX15B	1	0	0	1
Histamine H2 receptor	1	0	0	1
TAR DNA-binding protein 43	1	0	0	1
heat shock protein 90, putative	0	0	0	1
Chain A, Ferritin light chain	0	0	1	1
Chain A, Ferritin light chain	0	0	1	1
Chain A, Ferritin light chain	0	0	1	1
Chain A, Ferritin light chain	0	0	1	1
Chain A, Ferritin light chain	0	0	1	1
Chain A, Ferritin light chain	0	0	1	1
Chain A, Ferritin light chain	0	0	1	1
caspase 7, apoptosis-related cysteine protease	1	0	0	1
caspase-3	1	0	0	1
muscarinic acetylcholine receptor M1	1	0	0	1
Fatty-acid amide hydrolase 1	0	1	0	1
5-hydroxytryptamine receptor 4	0	2	0	2
Aldo-keto reductase family 1 member B1	0	3	0	3
Gamma-aminobutyric acid receptor subunit alpha-1	0	0	0	1
Gamma-aminobutyric acid receptor subunit beta-1	0	0	0	1
Gamma-aminobutyric acid receptor subunit alpha-2	0	0	0	1
Gamma-aminobutyric acid receptor subunit alpha-3	0	0	0	1
Gamma-aminobutyric acid receptor subunit alpha-4	0	0	0	1
Gamma-aminobutyric acid receptor subunit gamma-2	0	0	0	1
Sodium- and chloride-dependent GABA transporter 1	0	1	0	1
5-hydroxytryptamine receptor 2C	0	2	0	2
Sodium- and chloride-dependent GABA transporter 2	0	1	0	1
Sodium- and chloride-dependent GABA transporter 3	0	1	0	1
Sodium- and chloride-dependent betaine transporter	0	1	0	1
Fatty-acid amide hydrolase 1	0	1	0	1
UDP-glucuronosyltransferase 1A8	0	0	0	1
chaperonin-containing TCP-1 beta subunit homolog	1	0	0	1
Estrogen receptor beta	0	0	0	1
Inhibitor of nuclear factor kappa-B kinase subunit beta	0	0	0	1
Polyphenol oxidase 2	0	1	0	2
5'-AMP-activated protein kinase subunit beta-2	0	0	0	1
Albumin	0	1	0	1
Polymerase acidic protein	0	0	1	1
Stromelysin-1	0	0	1	1
Tyrosine-protein phosphatase YopH	0	1	0	1
High mobility group protein B1	0	0	1	1
Aldo-keto reductase family 1 member B1	0	1	0	1
Prolyl 4-hydroxylase subunit alpha-1	0	1	0	1
Tyrosine-protein phosphatase non-receptor type 1	0	1	0	3
Estrogen receptor	0	0	0	1
Cystathionine gamma-lyase	0	1	0	1
5'-AMP-activated protein kinase subunit gamma-1	0	0	0	1
5'-AMP-activated protein kinase catalytic subunit alpha-2	0	0	0	1
Xanthine dehydrogenase/oxidase	0	1	0	1
5'-AMP-activated protein kinase catalytic subunit alpha-1	0	0	0	1
Carbonic anhydrase	0	1	0	1
Solute carrier family 22 member 7	0	0	0	1
Nicotinate phosphoribosyltransferase	0	1	0	1
Solute carrier family 22 member 20	0	1	0	1
Solute carrier family 22 member 6	0	1	0	1
Ubiquitin-like domain-containing CTD phosphatase 1	0	1	0	1
5'-AMP-activated protein kinase subunit gamma-3	0	0	0	1
5'-AMP-activated protein kinase subunit gamma-2	0	0	0	1
5'-AMP-activated protein kinase subunit beta-1	0	0	0	1
Chain A, Acetylcholinesterase	0	0	1	1
Chain A, Acetylcholinesterase	0	0	1	1
Chain A, Acetylcholinesterase	0	0	1	1
Chain A, Acetylcholinesterase	0	0	1	1
Chain A, Acetylcholinesterase	0	0	1	1
Chain A, Acetylcholinesterase	0	0	1	1
Chain A, Acetylcholinesterase	0	0	1	1
Acetylcholinesterase	0	1	0	1
DNA polymerase kappa isoform 1	1	0	0	1
Nuclear receptor subfamily 1 group I member 2	0	0	1	1
UDP-glucuronosyltransferase 2B7	0	1	0	3
Cytochrome P450 3A5	0	1	0	1
UDP-glucuronosyltransferase 1A4	0	0	0	1
Serine/threonine-protein kinase mTOR	0	1	0	1
Peptidyl-prolyl cis-trans isomerase FKBP1A	0	2	1	3
Peptidyl-prolyl cis-trans isomerase FKBP1B	0	0	1	1
Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform	0	1	0	1
Peptidyl-prolyl cis-trans isomerase FKBP5	0	1	0	1
Splicing factor 3B subunit 3	0	1	0	1
Broad substrate specificity ATP-binding cassette transporter ABCG2	0	1	0	1
Solute carrier organic anion transporter family member 1B1	0	1	0	1
Cereblon isoform 4	0	2	0	2
Prostaglandin G/H synthase 2	0	1	0	1
cAMP-specific 3',5'-cyclic phosphodiesterase 4C	0	1	0	1
DNA-binding protein Ikaros	0	0	0	1
DNA damage-binding protein 1	0	1	1	2
Protein cereblon	0	2	1	4
Cocaine esterase	0	1	0	1
Histone deacetylase 3	0	2	0	2
Cytochrome P450 2A6	0	1	0	1
Aldo-keto reductase family 1 member A1	0	1	0	1
Aldo-keto reductase family 1 member A1	0	1	0	1
Histone deacetylase 4	0	2	0	2
Histone deacetylase 1	0	2	0	2
Aldo-keto reductase family 1 member A1	0	1	0	1
Aldo-keto reductase family 1 member B7	0	1	0	1
Sigma non-opioid intracellular receptor 1	0	1	0	1
Histone deacetylase 7	0	2	0	2
Histone deacetylase 2	0	2	0	2
Polyamine deacetylase HDAC10	0	2	0	2
Histone deacetylase 11	0	2	0	2
Histone deacetylase 8	0	2	0	2
NAD-dependent protein deacylase sirtuin-5, mitochondrial	0	1	0	1
Histone deacetylase 6	0	2	0	2
Histone deacetylase 9	0	2	0	2
Histone deacetylase 5	0	2	0	2
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]

Synonyms(6)

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Treatment

Research

Studies (87)

Protein Targets (486)

Amniotic Band Syndrome

Synonyms(6)

Research Excerpts

Overview

Actions

Treatment

Research

Studies (87)

Drugs Studied (30)

Protein Targets (486)