Alternating Exotropia

A form of ocular misalignment where the visual axes diverge inappropriately. For example, medial rectus muscle weakness may produce this condition as the affected eye will deviate laterally upon attempted forward gaze. An exotropia occurs due to the relatively unopposed force exerted on the eye by the lateral rectus muscle, which pulls the eye in an outward direction.

Synonym
Primary Exotropia
Exotropia
Secondary Exotropia
Exophoria
Alternating Exotropia
Divergent Strabismus
Strabismus, Divergent
Monocular Exotropia
Exodeviation

Excerpt	Reference
"Exotropia is rarely reported in thyroid eye disease (TED)."	( Kim, MM; Kim, WJ; Moon, JS, 2018)
"Recurrent exotropia is common following surgery for monocular large angle constant sensory exotropia."	( Enyedi, LB; Glaser, TS; Pineles, S; Ploysangam, P; Umfress, AC; Velez, FG, 2023)

Excerpt	Reference
"Intermittent exotropia (IXT) is the most common type of strabismus in China, but the best treatment and optimal timing of intervention for IXT remain controversial, particularly for children with moderate IXT who manifest obvious exodeviation frequently but with only partial impairment of binocular single vision."	( Chen, J; Deng, D; Jin, L; Kang, Y; Li, J; Lin, X; Qiu, X; Shen, T; Wang, Z; Wu, H; Yan, J, 2023)

Timeframe	Studies, This Condition (%)	All Conditions %
pre-1990	8 (7.55)	23.3326
1990's	15 (14.15)	12.5806
2000's	28 (26.42)	18.1394
2010's	38 (35.85)	28.8240
2020's	17 (16.04)	9.53

Drug	Relationship Strength	Studies	Trials
thiamine	low	1	0
acetazolamide	low	1	0
amitriptyline	low	2	0
aspirin	low	1	0
bupivacaine	low	3	0
carbamazepine	low	1	0
cefuroxime	low	1	0
cyclobenzaprine	low	1	0
diclofenac	low	1	0
flunitrazepam	medium	1	1
hydroxyzine	low	1	0
ibuprofen	low	1	0
lidocaine	low	1	0
2-propanol	low	2	0
ketamine	low	1	0
lorazepam	low	1	0
methadone	low	2	0
ofloxacin	low	1	0
proxymetacaine	low	1	0
propofol	low	2	0
sevoflurane	low	1	0
tranexamic acid	low	1	0
prednisolone	low	1	0
dextroamphetamine	low	2	0
prednisone	low	1	0
pilocarpine	low	1	0
lysine	low	2	0
levodopa	low	1	0
arginine	low	1	0
methylprednisolone	low	2	0
propoxycaine	low	1	0
fluorometholone	low	1	0
4-hydroxybutyric acid	medium	1	1
docusate	low	1	0
erythromycin	low	1	0
floxacillin	low	1	0
enbucrilate	low	1	0
timolol	low	1	0
propiconazole	low	25	0
atracurium	low	1	0
fomesafen	low	1	0
biocytin	low	1	0
deoxyglucose	low	1	0
pentosidine	low	1	0
proline	low	1	0
atropine	low	3	0
inositol 3-phosphate	low	1	0
rocuronium	low	1	0
melphalan	low	1	0
benztropine	low	1	0
methimazole	low	1	0
freedom	low	1	0
phenylephrine hydrochloride	low	1	0
heroin	low	1	0
jaw	low	1	0
vendex	low	1	0
ro13-9904	low	2	0
exudates	low	1	0
eye	medium	28	1

Protein Targets (717)

Protein	Potency Measurements	Inhibition Measurements	Activation Measurements	Drugs
hypoxia-inducible factor 1 alpha subunit	5	0	0	5
RAR-related orphan receptor gamma	9	0	0	9
GLI family zinc finger 3	13	0	0	13
AR protein	16	0	0	16
aldehyde dehydrogenase 1 family, member A1	7	0	0	7
retinoic acid nuclear receptor alpha variant 1	11	0	0	11
retinoid X nuclear receptor alpha	9	0	0	9
estrogen nuclear receptor alpha	18	0	0	18
peroxisome proliferator-activated receptor delta	4	0	0	4
cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a	9	0	0	9
activating transcription factor 6	2	0	0	2
v-jun sarcoma virus 17 oncogene homolog (avian)	5	0	0	5
Histone H2A.x	7	0	0	7
thyroid hormone receptor beta isoform a	4	0	0	4
heat shock protein beta-1	3	0	0	3
nuclear factor erythroid 2-related factor 2 isoform 1	10	0	0	10
lamin isoform A-delta10	15	0	0	15
Voltage-dependent calcium channel gamma-2 subunit	4	0	0	4
Glutamate receptor 2	4	0	0	4
Gamma-aminobutyric acid receptor subunit pi	6	6	2	14
Calcium/calmodulin-dependent protein kinase type II subunit alpha	0	2	0	2
Gamma-aminobutyric acid receptor subunit beta-1	6	6	2	14
Gamma-aminobutyric acid receptor subunit delta	6	6	2	14
Gamma-aminobutyric acid receptor subunit gamma-2	6	6	2	14
Gamma-aminobutyric acid receptor subunit alpha-5	6	6	2	14
Gamma-aminobutyric acid receptor subunit alpha-3	6	6	2	14
Gamma-aminobutyric acid receptor subunit gamma-1	6	6	2	14
Gamma-aminobutyric acid receptor subunit alpha-2	6	6	2	14
Gamma-aminobutyric acid receptor subunit alpha-4	6	6	2	14
Gamma-aminobutyric acid receptor subunit gamma-3	6	6	2	14
Gamma-aminobutyric acid receptor subunit alpha-6	6	6	2	14
Gamma-aminobutyric acid receptor subunit alpha-1	6	7	2	15
Gamma-aminobutyric acid receptor subunit beta-3	6	6	2	14
Gamma-aminobutyric acid receptor subunit beta-2	6	6	2	14
Tetraspanin	0	1	0	1
Proton-coupled amino acid transporter 1	0	2	0	2
GABA theta subunit	6	6	2	14
Gamma-aminobutyric acid receptor subunit epsilon	6	6	2	14
Calcium/calmodulin-dependent protein kinase type II subunit alpha	0	1	0	1
Chain A, TYROSYL-DNA PHOSPHODIESTERASE	6	0	0	6
Chain A, CARBONIC ANHYDRASE II	0	0	1	1
Chain A, CARBONIC ANHYDRASE II	0	0	1	1
Chain A, CARBONIC ANHYDRASE II	0	0	1	1
Chain A, Carbonic Anhydrase Ii	0	0	1	1
Chain A, Carbonic Anhydrase Ii	0	0	1	1
Chain A, Beta-lactamase	5	0	0	5
Chain A, Endochitinase	0	1	0	1
Chain A, Endochitinase	0	1	0	1
Chain A, Endochitinase	0	1	0	1
Chain A, Class Iii Chitinase Chia1	0	1	0	1
Chain A, Carbonic anhydrase 13	0	1	0	1
Chain A, Carbonic anhydrase II	0	1	0	1
Chain A, Carbonic anhydrase 2	0	1	0	1
Chain A, Carbonic anhydrase 2	0	1	0	1
Chain A, Carbonic anhydrase 2	0	1	0	1
Chain A, Carbonic anhydrase 2	0	1	0	1
Chain A, Carbonic anhydrase 2	0	1	0	1
Chain A, Carbonic anhydrase 2	0	1	0	1
Chain A, Carbonic anhydrase 2	0	1	0	1
Chain A, Carbonic anhydrase 2	0	1	0	1
Chain A, Carbonic anhydrase 2	0	1	0	1
Chain A, Carbonic anhydrase	0	1	0	1
Chain B, Carbonic anhydrase	0	1	0	1
Chain A, Carbonic anhydrase 2	0	1	0	1
Carbonic anhydrase	0	0	0	1
Carbonic anhydrase	0	1	0	1
thioredoxin reductase	12	0	0	12
GALC protein	2	0	0	2
nuclear receptor subfamily 1, group I, member 3	7	0	0	7
cytochrome P450 family 3 subfamily A polypeptide 4	13	0	0	13
glucocorticoid receptor [Homo sapiens]	13	0	0	13
estrogen-related nuclear receptor alpha	17	0	0	17
Carbonic anhydrase	0	1	0	1
Carbonic anhydrase	0	1	0	1
arylsulfatase A	7	0	0	7
Carbonic anhydrase	0	1	0	1
euchromatic histone-lysine N-methyltransferase 2	16	0	0	16
Bloom syndrome protein isoform 1	5	0	0	5
geminin	11	0	0	11
peripheral myelin protein 22	7	0	0	7
survival motor neuron protein isoform d	3	0	0	3
muscleblind-like protein 1 isoform 1	3	0	0	3
ATP-binding cassette sub-family C member 3	0	15	0	15
Multidrug resistance-associated protein 4	0	15	0	15
Carbonic anhydrase	0	1	0	1
Solute carrier family 22 member 6	0	3	0	3
Carbonic anhydrase 12	0	2	1	6
Prolyl endopeptidase	0	1	0	1
Carbonic anhydrase-related protein 11	0	1	0	2
Bile salt export pump	0	22	0	22
Glycogen phosphorylase, muscle form	0	1	0	1
Renin	0	2	0	2
Carbonic anhydrase 1	0	7	1	13
Carbonic anhydrase 2	0	7	1	12
Carbonic anhydrase 2	0	2	0	2
Cytochrome P450 1A2	0	1	0	1
Carbonic anhydrase 3	0	2	1	6
Cathepsin B	0	1	0	1
Cytochrome P450 3A4	0	4	0	5
Steryl-sulfatase	0	1	0	1
5-hydroxytryptamine receptor 2C	0	2	1	3
Polyunsaturated fatty acid 5-lipoxygenase	0	1	0	1
Cytochrome P450 2C8	0	1	0	1
Cytochrome P450 2D6	0	2	0	2
Cytochrome P450 2A6	0	2	1	3
Cytochrome P450 2C9	0	7	0	8
5-hydroxytryptamine receptor 2A	0	2	1	3
Androgen receptor	0	6	0	6
Translocator protein	0	1	0	1
Cannabinoid receptor 1	0	1	0	1
Arachidonate 5-lipoxygenase-activating protein	0	1	0	1
Cytochrome P450 2B6	0	2	1	3
Carbonic anhydrase 4	0	2	1	5
Carbonic anhydrase 6	0	3	1	6
Carbonic anhydrase 5A, mitochondrial	0	1	0	1
Adenosine receptor A1	0	3	0	4
Serum paraoxonase/arylesterase 1	0	1	0	1
Dipeptidyl peptidase 4	0	0	0	1
Endochitinase	0	1	0	1
Adenosine receptor A2a	0	3	0	4
5-hydroxytryptamine receptor 2B	0	2	1	3
Sodium-dependent serotonin transporter	0	2	1	3
Delta-type opioid receptor	0	1	0	1
Cytochrome P450 2C19	0	1	0	1
Delta-type opioid receptor	0	1	0	1
Mu-type opioid receptor	0	1	0	1
Carbonic anhydrase 5A, mitochondrial	0	2	1	6
Carbonic anhydrase	0	1	0	2
Kappa-type opioid receptor	0	1	0	1
Carbonic anhydrase 7	0	2	1	5
Carbonic anhydrase	0	1	0	1
D(1A) dopamine receptor	2	1	0	3
Corticosteroid 11-beta-dehydrogenase isozyme 1	0	1	0	1
Carbonic anhydrase	0	1	0	2
D(2) dopamine receptor	0	1	0	1
Cholinesterase	0	2	0	2
Carbonic anhydrase	0	1	0	1
Mu-type opioid receptor	0	2	0	2
Fatty-acid amide hydrolase 1	0	4	0	4
Beta-carbonic anhydrase 1	0	1	0	1
Carbonic anhydrase 2	0	1	0	1
Glutamate receptor ionotropic, NMDA 2B	0	3	0	4
Squalene synthase	0	1	0	1
Neuronal acetylcholine receptor subunit alpha-7	0	1	0	1
Carbonic anhydrase 9	0	3	1	7
Carbonic anhydrase	0	1	0	1
Carbonic anhydrase, alpha family	0	1	0	1
Carbonic anhydrase	0	1	0	2
Carbonic anhydrase 3	0	1	0	1
Carbonic anhydrase	0	1	0	3
Carbonic anhydrase	0	1	0	3
Carbonic anhydrase	0	1	0	1
Sigma intracellular receptor 2	0	1	0	1
Delta carbonic anhydrase	0	1	0	1
Sigma non-opioid intracellular receptor 1	0	1	1	2
Renin	0	1	0	1
Carbonic anhydrase	0	1	0	2
Endochitinase A1	0	1	0	1
Multidrug resistance-associated protein 1	0	1	0	1
Carbonic anhydrase 13	0	2	1	4
Canalicular multispecific organic anion transporter 1	0	15	0	15
Carbonic anhydrase 4	0	3	0	3
Carbonic anhydrase 15	0	1	0	3
Acidic mammalian chitinase	0	1	0	1
Carbonic anhydrase 13	0	2	0	4
Carbonic anhydrase 7	0	1	0	1
Carbonic anhydrase	0	1	0	1
Carbonic anhydrase 14	0	2	1	6
Carbonic anhydrase	0	1	0	1
Carbonic anhydrase 2, isoform A	0	1	0	1
Carbonic anhydrase 5B, mitochondrial	0	2	1	6
Chain A, HADH2 protein	5	0	0	5
Chain B, HADH2 protein	5	0	0	5
USP1 protein, partial	9	0	0	9
NFKB1 protein, partial	4	0	0	4
GLS protein	10	0	0	10
cytochrome P450 2D6	8	0	0	8
cytochrome P450 2D6 isoform 1	5	0	0	5
D(1A) dopamine receptor	4	0	0	4
chromobox protein homolog 1	10	0	0	10
atrial natriuretic peptide receptor 2 precursor	2	0	0	2
serine/threonine-protein kinase mTOR isoform 1	2	0	0	2
muscarinic acetylcholine receptor M1	8	0	0	8
Solute carrier family 22 member 1	0	3	0	4
Polyunsaturated fatty acid lipoxygenase ALOX15B	4	0	0	4
Voltage-dependent L-type calcium channel subunit alpha-1F	0	2	0	2
5-hydroxytryptamine receptor 4	0	8	0	8
Albumin	0	0	3	3
High affinity nerve growth factor receptor	0	1	2	3
Aldo-keto reductase family 1 member B1	0	6	0	6
Muscarinic acetylcholine receptor M2	0	7	2	12
Muscarinic acetylcholine receptor M4	0	6	1	9
Muscarinic acetylcholine receptor M1	0	6	1	10
Muscarinic acetylcholine receptor M3	0	5	1	9
Muscarinic acetylcholine receptor M4	0	5	1	9
Muscarinic acetylcholine receptor M5	0	5	1	9
Muscarinic acetylcholine receptor M5	0	7	1	10
Alpha-2A adrenergic receptor	0	4	0	4
Muscarinic acetylcholine receptor M2	0	6	1	11
Muscarinic acetylcholine receptor M1	0	7	3	13
Angiotensin-converting enzyme	0	2	0	2
D(2) dopamine receptor	0	4	0	4
Alpha-2B adrenergic receptor	0	4	0	4
Alpha-2C adrenergic receptor	0	4	0	4
5-hydroxytryptamine receptor 1A	0	4	2	6
Muscarinic acetylcholine receptor M3	0	6	1	9
D(1A) dopamine receptor	0	2	0	2
D(1B) dopamine receptor	0	1	0	1
UDP-glucuronosyltransferase 1A4	0	1	0	2
Sodium-dependent noradrenaline transporter	0	8	1	9
Histamine H2 receptor	0	4	0	4
Alpha-1D adrenergic receptor	0	6	0	6
5-hydroxytryptamine receptor 2A	0	5	0	5
5-hydroxytryptamine receptor 2C	0	8	0	8
5-hydroxytryptamine receptor 1B	0	4	1	5
5-hydroxytryptamine receptor 1D	0	1	1	2
5-hydroxytryptamine receptor 1F	0	1	1	2
5-hydroxytryptamine receptor 6	0	1	1	2
Histamine H1 receptor	0	1	0	1
Sodium-dependent serotonin transporter	0	5	1	6
5-hydroxytryptamine receptor 7	0	1	1	2
5-hydroxytryptamine receptor 5A	0	1	1	2
5-hydroxytryptamine receptor 5B	0	1	1	2
Histamine H1 receptor	0	5	0	5
D(3) dopamine receptor	0	5	0	5
Sodium channel protein type 1 subunit alpha	0	1	0	1
Sodium channel protein type 4 subunit alpha	0	4	0	5
UDP-glucuronosyltransferase 1A3	0	0	0	3
5-hydroxytryptamine receptor 3A	0	1	1	2
5-hydroxytryptamine receptor 2B	0	6	0	6
Alpha-1A adrenergic receptor	0	2	0	2
Histamine H2 receptor	5	1	0	8
5-hydroxytryptamine receptor 6	0	4	0	4
5-hydroxytryptamine receptor 7	0	2	0	2
Voltage-dependent N-type calcium channel subunit alpha-1B	0	2	0	2
Sodium channel protein type 7 subunit alpha	0	1	0	1
Voltage-dependent L-type calcium channel subunit alpha-1D	0	2	0	2
Sodium-dependent dopamine transporter	0	6	1	7
Potassium voltage-gated channel subfamily H member 2	0	7	0	7
Voltage-dependent L-type calcium channel subunit alpha-1S	0	2	0	2
Voltage-dependent L-type calcium channel subunit alpha-1C	0	2	0	2
Sodium channel protein type 5 subunit alpha	0	2	0	2
Sodium channel protein type 9 subunit alpha	0	4	0	4
5-hydroxytryptamine receptor 4	0	1	1	2
Nuclear receptor subfamily 3 group C member 3	0	2	0	2
Sodium channel protein type 2 subunit alpha	0	1	0	1
Ataxin-2	6	0	0	6
Sigma non-opioid intracellular receptor 1	0	6	1	7
5-hydroxytryptamine receptor 3B	0	1	1	2
Sodium channel protein type 3 subunit alpha	0	2	0	2
Sodium channel protein type 11 subunit alpha	0	1	0	1
Sodium channel protein type 8 subunit alpha	0	1	0	1
Histamine H3 receptor	0	1	0	1
Sodium channel protein type 10 subunit alpha	0	1	0	1
Chain A, MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASE	7	0	0	7
Chain E, LYSINE, ARGININE, ORNITHINE-BINDING PROTEIN	0	0	1	1
Chain E, LYSINE, ARGININE, ORNITHINE-BINDING PROTEIN	0	0	1	1
Chain E, LYSINE, ARGININE, ORNITHINE-BINDING PROTEIN	0	0	1	1
phosphopantetheinyl transferase	6	0	0	6
thyroid stimulating hormone receptor	5	0	0	5
alpha-galactosidase	1	0	0	1
cytochrome P450 2C19 precursor	3	0	0	3
flap endonuclease 1	5	0	0	5
DNA polymerase iota isoform a (long)	5	0	0	5
lethal factor (plasmid)	4	0	0	4
Nitric oxide synthase, endothelial	0	0	0	2
Nitric oxide synthase, brain	0	0	0	1
Nitric oxide synthase, brain	0	0	0	1
Nitric oxide synthase, inducible	0	0	0	1
Nitric oxide synthase, inducible	0	0	1	3
Cationic amino acid transporter 3	0	2	0	2
ATP-dependent phosphofructokinase	6	0	0	6
Chain A, Phospholipase A2 isoform 3	0	0	1	1
Chain A, 2-oxoglutarate Oxygenase	5	0	0	5
GTP-binding protein (rab7)	0	0	1	1
ras protein, partial	0	0	1	1
interleukin 8	1	0	0	1
hypothetical protein, conserved	1	0	0	1
EWS/FLI fusion protein	6	0	0	6
glucocerebrosidase	2	0	0	2
Rac1 protein	0	0	1	1
IDH1	6	0	0	6
cell division cycle 42 (GTP binding protein, 25kDa), partial	0	0	1	1
15-hydroxyprostaglandin dehydrogenase [NAD(+)] isoform 1	3	0	0	3
DNA polymerase kappa isoform 1	5	0	0	5
Prostaglandin-H2 D-isomerase	0	1	0	1
Prostaglandin G/H synthase 1	0	3	0	3
Prostaglandin G/H synthase 2	0	2	0	2
Epidermal growth factor receptor	0	3	0	3
Fatty acid-binding protein, liver	0	5	0	5
Integrin beta-3	0	1	0	1
Myeloperoxidase	0	1	0	1
Prostaglandin G/H synthase 1	0	4	0	4
Seed linoleate 13S-lipoxygenase-1	0	1	0	1
Integrin alpha-IIb	0	1	0	1
Glutathione hydrolase 1 proenzyme	0	1	0	1
Prostaglandin G/H synthase 1	0	5	0	5
Substance-P receptor	0	2	0	2
Prostaglandin G/H synthase 2	0	5	0	5
Urotensin-2 receptor	0	1	0	1
4-aminobutyrate aminotransferase, mitochondrial	0	2	0	2
Nuclear receptor ROR-gamma	3	0	0	3
Ras-related protein Rab-2A	0	0	1	1
Prostaglandin G/H synthase 2	0	4	0	4
Rho-associated protein kinase 2	0	1	0	1
Nicotinate phosphoribosyltransferase	0	1	0	1
Solute carrier family 22 member 20	0	2	0	2
Solute carrier family 22 member 6	0	2	0	2
Sigma non-opioid intracellular receptor 1	0	0	2	2
NPYLR7B	0	0	1	1
Amine oxidase [flavin-containing] A	0	0	1	1
Small conductance calcium-activated potassium channel protein 3	0	1	1	2
pregnane X nuclear receptor	12	0	0	12
cystic fibrosis transmembrane conductance regulator	0	1	0	1
DNA polymerase beta	1	0	0	1
short transient receptor potential channel 6 isoform 1	0	0	1	1
Muscarinic acetylcholine receptor M1	0	0	1	2
Muscarinic acetylcholine receptor M4	0	1	0	1
Reverse transcriptase/RNaseH	0	0	0	1
Muscarinic acetylcholine receptor	0	1	1	2
TDP1 protein	14	0	0	14
Spike glycoprotein	0	0	2	2
Replicase polyprotein 1ab	0	0	2	2
potassium voltage-gated channel subfamily H member 2 isoform d	4	0	0	4
thyroid hormone receptor beta isoform 2	8	0	0	8
Transmembrane protease serine 2	0	0	2	2
Cellular tumor antigen p53	10	0	0	10
Procathepsin L	0	0	2	2
Replicase polyprotein 1a	0	0	2	2
Replicase polyprotein 1ab	0	0	2	2
Replicase polyprotein 1ab	0	0	2	2
Replicase polyprotein 1ab	0	0	2	2
Sodium-dependent dopamine transporter	0	1	1	2
Spike glycoprotein	7	0	2	9
Angiotensin-converting enzyme 2	0	0	2	2
Potassium channel subfamily K member 3	0	2	0	2
Potassium channel subfamily K member 3	0	1	0	1
Potassium channel subfamily K member 2	0	1	1	2
Potassium channel subfamily K member 9	0	1	0	1
acetylcholinesterase	2	0	0	2
nuclear factor erythroid 2-related factor 2 isoform 2	5	0	0	5
mitogen-activated protein kinase 1	2	0	0	2
Vpr	2	0	0	2
Bile salt export pump	0	4	0	4
Major prion protein	0	0	1	1
Sodium channel protein type 1 subunit alpha	0	2	0	2
Sodium channel protein type 2 subunit alpha	0	2	0	2
Sodium channel protein type 3 subunit alpha	0	2	0	2
UDP-glucuronosyltransferase 2B7	0	1	0	4
Cytochrome P450 2J2	0	5	0	5
Frizzled-8	0	0	1	1
P2X purinoceptor 4	0	1	0	1
15-lipoxygenase, partial	3	0	0	3
ATAD5 protein, partial	2	0	0	2
Fumarate hydratase	2	0	0	2
PPM1D protein	2	0	0	2
Thrombopoietin	1	0	0	1
polyprotein	2	0	0	2
cellular tumor antigen p53 isoform a	1	0	0	1
atrial natriuretic peptide receptor 1 precursor	2	0	0	2
Interferon beta	6	0	0	6
Inositol monophosphatase 1	1	0	0	1
Phenylethanolamine N-methyltransferase	0	1	0	1
Amine oxidase [flavin-containing] B	0	1	0	1
Amine oxidase [flavin-containing] A	0	2	0	2
Amine oxidase [flavin-containing] B	0	1	0	1
Amine oxidase [flavin-containing] B	0	1	0	1
Trace amine-associated receptor 1	0	0	1	1
Trace amine-associated receptor 1	0	0	1	1
Trace amine-associated receptor 1	0	0	1	1
Trace amine-associated receptor 1	0	0	1	1
Aldo-keto reductase family 1 member B10	0	1	0	1
UDP-glucuronosyltransferase 1A9	0	1	0	3
Transient receptor potential cation channel subfamily A member 1	0	0	1	1
Dihydrofolate reductase	0	2	0	2
Cytochrome c oxidase subunit 2	0	1	0	1
Transthyretin	0	0	1	3
Albumin	0	2	4	6
Interleukin-8	0	1	0	1
Fatty acid-binding protein, intestinal	0	2	0	2
Aldo-keto reductase family 1 member B1	0	1	0	1
UDP-glucuronosyltransferase 1-6	0	2	0	2
UDP-glucuronosyltransferase 1A1	0	2	0	2
Sodium- and chloride-dependent GABA transporter 1	0	3	0	3
C-X-C chemokine receptor type 1	0	1	0	1
Sodium- and chloride-dependent GABA transporter 2	0	3	0	3
Sodium- and chloride-dependent GABA transporter 3	0	3	0	3
Prostaglandin G/H synthase 2	0	2	0	3
UDP-glucuronosyltransferase 2B10	0	1	0	1
Sodium- and chloride-dependent betaine transporter	0	3	0	3
Prostaglandin G/H synthase 2	0	2	0	2
Solute carrier family 22 member 6	0	2	0	2
Prostaglandin G/H synthase 1	0	2	0	3
Multidrug and toxin extrusion protein 1	0	3	0	3
P2Y purinoceptor 12	0	1	0	1
UDP-glucuronosyltransferase 1A7	0	1	0	1
UDP-glucuronosyltransferase 1A10	0	1	0	1
Motilin receptor	0	0	1	1
acid sphingomyelinase	1	0	0	1
low molecular weight phosphotyrosine protein phosphatase isoform c	0	1	0	1
serine/threonine-protein kinase PLK1	1	0	0	1
streptokinase A precursor	0	0	2	2
Motilin receptor	0	1	1	2
Rap guanine nucleotide exchange factor 3	2	0	0	2
30S ribosomal protein S6	0	1	1	2
30S ribosomal protein S7	0	1	1	2
50S ribosomal protein L15	0	1	1	2
ATP-dependent translocase ABCB1	0	2	0	2
ATP-dependent translocase ABCB1	0	3	0	3
60 kDa chaperonin	0	1	0	1
50S ribosomal protein L10	0	1	1	2
50S ribosomal protein L11	0	1	1	2
50S ribosomal protein L7/L12	0	1	1	2
50S ribosomal protein L19	0	1	1	2
50S ribosomal protein L1	0	1	1	2
50S ribosomal protein L20	0	1	1	2
50S ribosomal protein L27	0	1	1	2
50S ribosomal protein L28	0	1	1	2
50S ribosomal protein L29	0	1	1	2
50S ribosomal protein L31	0	1	1	2
50S ribosomal protein L31 type B	0	1	1	2
50S ribosomal protein L32	0	1	1	2
50S ribosomal protein L33	0	1	1	2
50S ribosomal protein L34	0	1	1	2
50S ribosomal protein L35	0	1	1	2
50S ribosomal protein L36	0	1	1	2
30S ribosomal protein S10	0	1	1	2
30S ribosomal protein S11	0	1	1	2
30S ribosomal protein S12	0	1	1	2
30S ribosomal protein S13	0	1	1	2
30S ribosomal protein S16	0	1	1	2
30S ribosomal protein S18	0	1	1	2
30S ribosomal protein S19	0	1	1	2
30S ribosomal protein S20	0	1	1	2
30S ribosomal protein S2	0	1	1	2
30S ribosomal protein S3	0	1	1	2
30S ribosomal protein S4	0	1	1	2
30S ribosomal protein S5	0	1	1	2
30S ribosomal protein S8	0	1	1	2
30S ribosomal protein S9	0	1	1	2
50S ribosomal protein L13	0	1	1	2
50S ribosomal protein L14	0	1	1	2
50S ribosomal protein L16	0	1	1	2
50S ribosomal protein L23	0	1	1	2
30S ribosomal protein S15	0	1	1	2
50S ribosomal protein L17	0	1	1	2
50S ribosomal protein L21	0	1	1	2
50S ribosomal protein L30	0	1	1	2
50S ribosomal protein L6	0	1	1	2
30S ribosomal protein S14	0	1	1	2
30S ribosomal protein S17	0	1	1	2
30S ribosomal protein S1	0	1	1	2
50S ribosomal protein L18	0	1	1	2
60 kDa heat shock protein, mitochondrial	0	1	0	1
Chitinase B	0	1	0	1
ATP-dependent translocase ABCB1	0	2	0	2
Low molecular weight phosphotyrosine protein phosphatase	0	1	0	1
50S ribosomal protein L2	0	1	1	2
50S ribosomal protein L3	0	1	1	2
50S ribosomal protein L24	0	1	1	2
50S ribosomal protein L4	0	1	1	2
50S ribosomal protein L22	0	1	1	2
10 kDa heat shock protein, mitochondrial	0	1	0	1
50S ribosomal protein L5	0	1	1	2
30S ribosomal protein S21	0	1	1	2
50S ribosomal protein L25	0	1	1	2
Cytochrome P450 1B1	0	1	0	1
Thiosulfate sulfurtransferase	0	1	0	1
Lanosterol 14-alpha demethylase	0	2	0	2
50S ribosomal protein L36 2	0	1	1	2
60 kDa chaperonin	0	1	0	1
10 kDa chaperonin	0	1	0	1
Solute carrier family 15 member 1	0	2	0	2
Gamma-aminobutyric acid receptor subunit pi	0	1	0	1
Gamma-aminobutyric acid receptor subunit delta	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-1	0	3	3	6
Gamma-aminobutyric acid receptor subunit beta-1	0	1	1	2
Gamma-aminobutyric acid receptor subunit gamma-2	0	3	2	5
Gamma-aminobutyric acid receptor subunit beta-3	0	3	1	4
Translocator protein	0	2	0	2
Cholecystokinin receptor type A	0	1	0	1
Gastrin/cholecystokinin type B receptor	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-5	0	2	2	4
Gamma-aminobutyric acid receptor subunit alpha-3	0	2	1	3
Gamma-aminobutyric acid receptor subunit alpha-2	0	2	1	3
Gamma-aminobutyric acid receptor subunit beta-2	0	2	2	4
Gamma-aminobutyric acid receptor subunit alpha-4	0	1	1	2
Gamma-aminobutyric acid receptor subunit epsilon	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-6	0	2	1	3
Gamma-aminobutyric acid receptor subunit gamma-1	0	1	0	1
Gamma-aminobutyric acid receptor subunit gamma-3	0	1	0	1
Gamma-aminobutyric acid receptor subunit theta	0	1	0	1
hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)	7	0	0	7
progesterone receptor	9	0	0	9
G	4	0	0	4
nuclear receptor subfamily 1, group I, member 2	3	0	0	3
lysosomal alpha-glucosidase preproprotein	2	0	0	2
huntingtin isoform 2	1	0	0	1
peptidyl-prolyl cis-trans isomerase NIMA-interacting 1	3	0	0	3
nuclear receptor ROR-gamma isoform 1	4	0	0	4
Nuclear receptor subfamily 1 group I member 2	0	0	2	2
HLA class I histocompatibility antigen, B alpha chain	4	0	0	4
Glucocorticoid receptor	0	8	2	15
Glycine receptor subunit alpha-1	0	8	0	8
Neuronal acetylcholine receptor subunit alpha-4	2	0	0	2
Neuronal acetylcholine receptor subunit beta-2	2	0	0	2
Glycine receptor subunit beta	0	8	0	8
Glycine receptor subunit alpha-2	0	8	0	8
Glycine receptor subunit alpha-3	0	8	0	8
TAR DNA-binding protein 43	4	0	0	4
Inositol hexakisphosphate kinase 1	4	0	0	4
Nuclear receptor subfamily 1 group I member 2	0	0	2	2
cytochrome P450 2C9, partial	4	0	0	4
Luciferase	5	0	0	5
peroxisome proliferator activated receptor gamma	6	0	0	6
vitamin D (1,25- dihydroxyvitamin D3) receptor	6	0	0	6
Liver carboxylesterase 1	0	0	0	1
Alpha-1B adrenergic receptor	0	1	0	1
Alpha-1D adrenergic receptor	0	1	0	1
Histamine H4 receptor	0	1	0	1
nonstructural protein 1	3	0	0	3
67.9K protein	1	0	0	1
aryl hydrocarbon receptor	4	0	0	4
transcriptional regulator ERG isoform 3	1	0	0	1
importin subunit beta-1 isoform 1	3	0	0	3
snurportin-1	3	0	0	3
Acid-sensing ion channel 3	0	1	0	1
Solute carrier organic anion transporter family member 1A4	0	1	0	1
Albumin	0	1	0	1
Cholinesterase	0	1	0	1
Polyunsaturated fatty acid 5-lipoxygenase	0	1	0	2
Acetylcholinesterase	0	1	0	1
Prostaglandin G/H synthase 1	0	1	0	1
Caspase-1	0	1	0	1
Aldo-keto reductase family 1 member C3	0	1	0	1
Caspase-3	0	1	0	1
Solute carrier organic anion transporter family member 1A1	0	1	0	1
Caspase-4	0	1	0	1
Caspase-5	0	1	0	1
Caspase-9	0	1	0	1
Acid-sensing ion channel 1	0	1	0	1
Solute carrier family 22 member 8	0	1	0	1
Dehydrogenase/reductase SDR family member 9	0	1	0	1
Chymotrypsinogen A	0	1	0	1
Glutamate receptor ionotropic, NMDA 2D	0	1	0	1
Acetylcholinesterase	0	1	0	1
Glutamate receptor ionotropic, NMDA 3B	0	1	0	1
Glutamate receptor ionotropic, NMDA 1	0	3	0	4
Glutamate receptor ionotropic, NMDA 2A	0	2	0	3
Glutamate receptor ionotropic, NMDA 2C	0	2	0	3
Glutamate receptor ionotropic, NMDA 1	0	2	0	2
Glutamate receptor ionotropic, NMDA 2A	0	2	0	2
Glutamate receptor ionotropic, NMDA 2B	0	2	0	2
Glutamate receptor ionotropic, NMDA 2C	0	1	0	1
Glutamate receptor ionotropic, NMDA 2D	0	2	0	3
Glutamate receptor ionotropic, NMDA 3A	0	1	0	1
Glutamate receptor ionotropic, NMDA 3B	0	2	0	3
Glutamate receptor ionotropic, NMDA 3A	0	2	0	3
Chain A, Lectin	0	0	1	1
Chain A, Lectin	0	0	1	1
Chain A, Lectin	0	0	1	1
Chain A, Lectin	0	0	1	1
Chain A, ERYTHRINA CRISTA-GALLI LECTIN	0	0	1	1
Chain A, ERYTHRINA CRISTA-GALLI LECTIN	0	0	1	1
Chain A, cellulase	0	0	1	1
Chain A, cellulase	0	0	1	1
Chain A, Galectin-3	0	0	1	1
Chain A, Anti-tumor lectin	0	1	0	1
Galectin-3	0	1	0	1
Galectin-9	0	0	1	1
Galectin-8	0	0	1	1
Beta-galactoside-binding lectin	0	1	0	1
Galectin-1	0	1	1	3
Galectin-3	0	1	1	2
Galectin-3	0	1	1	3
Galectin-7	0	0	1	1
Alpha 1,4 galactosyltransferase	0	0	0	1
Chain A, JmjC domain-containing histone demethylation protein 3A	2	0	0	2
Chain A, ATP-DEPENDENT DNA HELICASE Q1	1	0	0	1
dopamine D1 receptor	1	0	0	1
WRN	1	0	0	1
integrase, partial	0	1	0	1
lens epithelium-derived growth factor p75	0	1	0	1
apical membrane antigen 1, AMA1	1	0	0	1
pyruvate kinase	1	0	0	1
hexokinase-4 isoform 1	1	0	0	1
glucokinase regulatory protein	1	0	0	1
ubiquitin carboxyl-terminal hydrolase 2 isoform a	1	0	0	1
DNA polymerase eta isoform 1	1	0	0	1
M-phase phosphoprotein 8	1	0	0	1
Polyphenol oxidase 2	0	2	0	4
Plasma kallikrein	0	0	0	1
Tyrosine-protein kinase Lck	0	1	0	1
Tyrosine-protein kinase Fyn	0	1	0	1
Polyunsaturated fatty acid lipoxygenase ALOX15	0	2	0	2
Tyrosinase	0	1	0	1
Large neutral amino acids transporter small subunit 1	0	1	0	1
SLC16A10 protein	0	0	0	1
Carbonic anhydrase-like protein, putative	0	0	0	1
Monocarboxylate transporter 10	0	0	0	1
phosphoglycerate kinase	1	0	0	1
Microtubule-associated protein tau	1	0	0	1
cytochrome P450 3A4 isoform 1	6	0	0	6
Potassium voltage-gated channel subfamily A member 5	0	1	0	1
Potassium voltage-gated channel subfamily D member 2	0	1	0	1
Potassium channel subfamily K member 18	0	1	0	1
Chain A, Ribulose-1,5 bisphosphate carboxylase/oxygenase large subunit N-methyltransferase, chloroplast	0	1	0	1
Chain A, Ribulose-1,5 bisphosphate carboxylase/oxygenase large subunit N-methyltransferase, chloroplast	0	1	0	1
Glutathione reductase, mitochondrial	0	2	0	2
glp-1 receptor, partial	3	0	0	3
thioredoxin glutathione reductase	2	0	0	2
Smad3	1	0	0	1
caspase 7, apoptosis-related cysteine protease	2	0	0	2
estrogen receptor 2 (ER beta)	4	0	0	4
farnesoid X nuclear receptor	4	0	0	4
caspase-3	2	0	0	2
Caspase-7	1	0	0	1
caspase-3	1	0	0	1
urokinase-type plasminogen activator precursor	1	0	0	1
plasminogen precursor	1	0	0	1
urokinase plasminogen activator surface receptor precursor	1	0	0	1
Large neutral amino acids transporter small subunit 1	0	1	0	1
ATPase family AAA domain-containing protein 5	4	0	0	4
D(4) dopamine receptor	0	1	0	1
Mu-type opioid receptor	0	2	0	2
Delta-type opioid receptor	0	1	0	1
Kappa-type opioid receptor	0	1	0	1
Mas-related G-protein coupled receptor member X2	0	0	1	1
Aldehyde oxidase 1	0	1	0	1
Dopamine beta-hydroxylase	0	2	0	2
Lactoperoxidase	0	1	0	1
bromodomain adjacent to zinc finger domain 2B	1	0	0	1
Chain A, Ferritin light chain	4	0	0	4
STE24	0	0	0	1
parathyroid hormone/parathyroid hormone-related peptide receptor precursor	1	0	0	1
CAAX prenyl protease	0	0	0	1
histone acetyltransferase KAT2A isoform 1	3	0	0	3
Trypsin	0	0	0	1
DNA gyrase subunit A	0	1	0	2
DNA gyrase subunit B	0	1	0	2
DNA gyrase subunit B	0	1	0	2
DNA gyrase subunit A	0	1	0	2
thyroid stimulating hormone receptor	1	0	0	1
beta-2 adrenergic receptor	1	0	0	1
mu-type opioid receptor isoform MOR-1	0	0	1	1
5-hydroxytryptamine receptor 2A	0	0	1	1
regulator of G-protein signaling 4	2	0	0	2
cytochrome P450 2C9 precursor	1	0	0	1
Muscarinic acetylcholine receptor DM1	0	1	0	1
Cytochrome P450 2A13	0	1	1	2
luciferase	0	0	0	1
Estrogen receptor	0	2	0	2
Progesterone receptor	0	2	0	3
Glucocorticoid receptor	0	1	1	2
Glucocorticoid receptor	0	0	1	1
Corticosteroid-binding globulin	0	1	0	1
Mineralocorticoid receptor	0	2	1	3
Androgen receptor	0	2	0	2
Glutamine synthetase	0	0	1	1
Histamine H1 receptor	0	0	1	1
Nociceptin receptor	0	0	1	1
Estrogen receptor beta	0	2	0	2
pregnane X receptor	2	0	0	2
vitamin D3 receptor isoform VDRA	3	0	0	3
Glutamate 5-kinase	0	0	0	1
Angiotensin-converting enzyme	0	1	0	1
Neutral amino acid transporter A	0	1	0	1
Neutral amino acid transporter B(0)	0	1	0	1
Amino acid transporter	0	1	0	1
SMAD family member 2	1	0	0	1
SMAD family member 3	1	0	0	1
heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)	1	0	0	1
heat shock protein HSP 90-alpha isoform 2	0	0	0	1
Guanine nucleotide-binding protein G	1	0	0	1
heat shock protein 90, putative	0	0	0	1
Chain A, Ferritin light chain	0	0	1	1
Chain A, Ferritin light chain	0	0	1	1
Chain A, Ferritin light chain	0	0	1	1
Chain A, Ferritin light chain	0	0	1	1
Chain A, Ferritin light chain	0	0	1	1
Chain A, Ferritin light chain	0	0	1	1
Chain A, Ferritin light chain	0	0	1	1
nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105), isoform CRA_a	2	0	0	2
Fatty-acid amide hydrolase 1	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-1	0	0	0	2
Gamma-aminobutyric acid receptor subunit beta-1	0	0	0	2
Gamma-aminobutyric acid receptor subunit alpha-2	0	0	0	2
Gamma-aminobutyric acid receptor subunit alpha-3	0	0	0	2
Gamma-aminobutyric acid receptor subunit alpha-4	0	0	0	2
Gamma-aminobutyric acid receptor subunit gamma-2	0	0	0	2
UDP-glucuronosyltransferase 1A8	0	0	0	1
Chain A, Acetylcholinesterase	0	0	1	1
Chain A, Acetylcholinesterase	0	0	1	1
Chain A, Acetylcholinesterase	0	0	1	1
Chain A, Acetylcholinesterase	0	0	1	1
Chain A, Acetylcholinesterase	0	0	1	1
Chain A, Acetylcholinesterase	0	0	1	1
Chain A, Acetylcholinesterase	0	0	1	1
Acetylcholinesterase	0	1	0	1
Chain A, ykoF	0	0	1	1
Chain B, ykoF	0	0	1	1
Chain A, ThiT	0	0	1	1
Thiamine transporter ThiT	0	0	1	1
Transketolase	0	0	1	1
Thiamine-binding periplasmic protein	0	0	1	1
Solute carrier family 22 member 1	0	1	0	1
Solute carrier family 22 member 2	0	1	0	1
Beta-1 adrenergic receptor	0	0	1	1
Beta-2 adrenergic receptor	0	2	0	2
Beta-1 adrenergic receptor	0	2	0	2
Beta-3 adrenergic receptor	0	2	0	2
Beta-1 adrenergic receptor	0	1	0	1
Beta-2 adrenergic receptor	0	0	1	1
Chain A, PLASMINOGEN	0	0	1	1
Chain A, PLASMINOGEN	0	0	1	1
Plasminogen	0	2	1	3
Urokinase-type plasminogen activator	0	1	0	1
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]

Synonyms(9)

Research Excerpts

Overview

Treatment

Research

Studies (106)

Protein Targets (717)

Alternating Exotropia

Synonyms(9)

Research Excerpts

Overview

Treatment

Research

Studies (106)

Drugs Studied (67)

Protein Targets (717)