Adult Neuronal Ceroid Lipofuscinosis

This type is caused by mutation in the gene (CLN1or PPT1) encoding palmitoyl-protein thioesterase (THIOLESTER HYDROLASES), an enzyme involved in catabolism of lipid-modified proteins.

Synonym
Kufs Disease
Spielmeyer-Sjogren Disease
CLN3-Related Neuronal Ceroid-Lipofuscinosis
CLN4A
CLN4B
Neuronal Ceroid-Lipofuscinosis
Jansky-Bielschowsky Disease
Neuronal Ceroid Lipofuscinosis, Late-Infantile
Adult Neuronal Ceroid Lipofuscinosis
Neuronal Ceroid Lipofuscinosis, Late Infantile
Neuronal Ceroid Lipofuscinosis, Juvenile
Neuronal Ceroid Lipofuscinosis, Infantile
Neuronal Ceroid Lipofuscinosis, Adult Type
Vogt-Spielmeyer Disease
Vogt Spielmeyer Disease
Neuronal Ceroid Lipofuscinosis, Adult
Neuronal Ceroid Lipofuscinosis Juvenile Type
Neuronal Ceroid Lipofuscinosis
Ceroid-Lipofuscinosis, Neuronal
Ceroid Storage Disease
Ceroid Lipofuscinosis, Neuronal, Parry Type
Ceroid Lipofuscinosis, Neuronal, 4B, Autosomal Dominant
Spielmeyer-Vogt Disease
Santavuori-Haltia Disease
Ceroid Lipofuscinosis, Neuronal, 4A, Autosomal Recessive
Ceroid Lipofuscinosis, Neuronal, 3
Ceroid Lipofuscinosis, Neuronal 3, Juvenile
Juvenile Cerebroretinal Degeneration
Ceroid Lipofuscinosis, Neuronal 4
Infantile Neuronal Ceroid Lipofuscinosis
Juvenile Batten Disease
Kufs Type Neuronal Ceroid Lipofuscinosis
Kufs Disease, Autosomal Recessive
Kufs Disease, Autosomal Dominant
Kufs Disease Autosomal Recessive
Lipofuscinosis, Neuronal Ceroid
Lipofuscin Storage Disease
Kuf's Disease
Juvenile Neuronal Ceroid Lipofuscinosis
Amaurotic Idiocy, Adult Type
Batten Disease
Batten-Mayou Disease
Batten-Spielmeyer-Vogt Disease
Late-Infantile Neuronal Ceroid Lipofuscinosis

Excerpt	Reference
"Juvenile neuronal ceroid lipofuscinosis is a lysosomal storage disease that causes visual impairment, progressive mental deterioration, and eventually death."	( Davidson, BL; Derksen, TA; Haskell, RE, 1999)
"Juvenile Batten disease is a neurodegenerative disease caused by accelerated apoptotic death of photoreceptors and neurons attributable to defects in the CLN3 gene."	( Amalfitano, A; Boustany, RM; Chang, J; Guo, WX; Jansen, PJ; Persaud-Sawin, DA; Proia, AD; Rylova, SN, 2002)
"Ocularly, Batten disease is characterized by a rapid deterioration of vision, progressing to blindness within a few years."	( Wilkinson, ME, 2001)
"Batten disease is the most likely of the ceroid lipofuscinoses to be manifested in an ophthalmic practitioner's office before the diagnosis of the underlying condition."	( Wilkinson, ME, 2001)
"Infantile Batten disease is a severe neurodegenerative storage disorder caused by mutations in the human PPT1 (palmitoyl protein thioesterase 1) gene, which encodes a lysosomal hydrolase that removes fatty acids from lipid-modified proteins."	( Cho, SK; Hofmann, SL, 2004)
"Juvenile neuronal ceroid lipofuscinosis is an inherited pediatric neurodegenerative disorder, which occurs as a result of mutations in the CLN3 gene that is located on chromosome 16p12."	( Bennett, MJ; Narayan, SB; Pastor, JV; Rakheja, D, 2004)
"Pathologically, Batten disease is characterized by lysosomal storage of autofluorescent material in all tissue types."	( Brooks, AI; Chattopadhyay, S; Curran, TM; Kingsley, E; Pearce, DA; Serour, A, 2004)
"Juvenile Batten disease is a progressive neurodegenerative disorder of childhood that results from mutation in Cln3."	( Benedict, JW; Pearce, DA; Sommers, CA, 2007)
"Neuronal ceroid lipofuscinosis is a severe neurodegenerative lysosomal storage disorder."	( Le, NM; Parikh, S, 2012)
"Batten disease is an inherited disorder characterized by early onset neurodegeneration due to the mutation of the CLN3 gene."	( Heo, TH; Kim, JB; Kim, SJ; Lim, N, 2012)
"Batten disease is an inherited neurodegenerative disorder caused by a CLN3 gene mutation."	( Heo, TH; Kang, S; Kim, JB; Kim, SJ, 2013)
"Batten disease (juvenile neuronal ceroid lipofuscinosis) is a neurodegenerative disorder characterized by blindness, seizures, cognitive decline, and early death due to the inherited mutation of the CLN3 gene."	( Heo, TH; Kang, S; Kim, SJ, 2014)
"Infantile neuronal ceroid lipofuscinosis is a devastating neurodegenerative lysosomal storage disease caused by mutations in the gene (CLN1 or PPT1) encoding palmitoyl-protein thioesterase-1 (PPT1)."	( Baker, EH; Bianconi, S; Caruso, RC; Chandra, G; Griffin, KJ; Gropman, A; Khan, OI; Levin, SW; Liu, A; Miao, N; Mukherjee, AB; Quezado, ZM; Zein, WM; Zhang, Z, 2014)
"Abstract Juvenile Neuronal Ceroid Lipofuscinosis is a lysosomal storage disease characterized pathologically by intracellular accumulation of autofluorescent storage material and neurodegeneration."	( Augustine, EF; Mink, JW, 2016)
"Infantile neuronal ceroid lipofuscinosis is a devastating neurodegenerative storage disease caused by palmitoyl-protein thioesterase 1 deficiency, which impairs degradation of palmitoylated proteins (constituents of ceroid) by lysosomal hydrolases."	( Baker, EH; Levin, SW; Mukherjee, AB; Zhang, Z, 2017)
"Late-infantile neuronal ceroid lipofuscinosis is a fatal neurodegenerative disease of children caused by mutations resulting in loss of activity of the lysosomal protease, tripeptidyl peptidase 1 (TPP1)."	( El-Banna, M; Lobel, P; Nemtsova, Y; Sleat, DE; Wiseman, JA, 2018)
"The etiology of Batten disease is linked to mutations in 13 genes that encode distinct CLN proteins, whose functions have yet to be fully elucidated."	( Huber, RJ; Remtulla, AAN, 2023)

Excerpt	Reference
"Five patients with Juvenile and one with Infantile Neuronal Ceroid Lipofuscinosis were treated with antioxidants along with vitamins E, B2 and B6, but this treatment did not affect significantly the concentration of iron in the mononuclear cells."	( Heiskala, H; Johansson, E; Lindh, U; Santavuori, P; Westermarck, T, 1990)
"An 11-year-old girl with juvenile neuronal ceroid lipofuscinosis developed acute pancreatitis secondary to valproic acid treatment, which resolved after discontinuation of the medication and conservative treatment."	( Talwar, D, 1994)
"We present a patient with juvenile neuronal ceroid lipofuscinosis who developed a neuroleptic malignant syndrome when treated for hallucinations with a very low dose of risperidone, an atypical neuroleptic medication with usually few extrapyramidal side-effects."	( Buyse, GM; Proost, JE; Van Hove, JL; Vercammen, L, 2003)
"Currently there is no treatment for juvenile Batten disease, a fatal childhood neurodegenerative disorder caused by mutations in the CLN3 gene."	( Cooper, JD; Kovács, AD; Pearce, DA; Ramji, S; Saje, A; Wong, A, 2012)
"The treatment of Batten disease cells with NAC for 48 h attenuated activities of the urea cycle and of DNA repair, as indicated by the substantially decreased expression levels of carbamoyl phosphate synthetase 1, 8-oxoguanine DNA glycosylase 1 and DNA polymerase beta proteins compared with untreated Batten cells."	( Heo, TH; Kim, JB; Kim, SJ; Lim, N, 2012)
"CLN3 disease (Spielmeyer-Vogt-Sjogren-Batten disease) is a severe pediatric neurodegenerative disorder for which there is currently no effective treatment."	( An Haack, K; Bennett, MJ; Li, C; Narayan, SB; Tan, L; Warnock, A, 2013)
"Infantile neuronal ceroid lipofuscinosis (INCL) is a devastating childhood neurodegenerative lysosomal storage disease (LSD) that has no effective treatment."	( Chandra, G; Liu, A; Mukherjee, AB; Peng, S; Sarkar, C; Zhang, Z, 2013)
"Ten patients with infantile neuronal ceroid lipofuscinosis participating in a treatment/follow-up study underwent brain MR imaging that included high-resolution T1-weighted images."	( Baker, EH; Levin, SW; Mukherjee, AB; Zhang, Z, 2017)

Timeframe	Studies, This Condition (%)	All Conditions %
pre-1990	59 (15.61)	23.3326
1990's	99 (26.19)	12.5806
2000's	101 (26.72)	18.1394
2010's	95 (25.13)	28.8240
2020's	24 (6.35)	9.53

Drug	Relationship Strength	Studies	Trials
acetylcarnitine	low	1	0
alpha-hydroxyglutarate	low	1	0
gamma-aminobutyric acid	medium	11	1
acetic acid	low	1	0
adenine	low	2	0
carnitine	low	9	0
choline	low	4	0
methylmalonic acid	low	2	0
malic acid	low	1	0
creatine	low	4	0
lactic acid	low	1	0
glycerol	low	1	0
hydroxylamine	low	1	0
inositol	low	4	0
melatonin	medium	3	2
orotic acid	low	1	0
palmitic acid	low	3	0
pyridoxine	low	1	0
selenious acid	low	2	0
succinic acid	low	1	0
taurine	low	2	0
trimethyloxamine	low	1	0
uric acid	low	1	0
urea	low	2	0
1,10-phenanthroline	low	1	0
1-anilino-8-naphthalenesulfonate	low	2	0
amlodipine	low	2	0
bay-k-8644	low	1	0
verapamil	low	1	0
carisoprodol	low	1	0
chloroquine	low	3	0
citalopram	medium	1	1
clenbuterol	low	1	0
clofazimine	low	1	0
clonazepam	medium	1	1
deferoxamine	low	1	0
valproic acid	medium	6	1
erythrosine	low	1	0
ethosuximide	low	1	0
fenofibrate	low	3	0
fentanyl	medium	1	1
flumazenil	low	2	0
fluspirilene	low	1	0
gemfibrozil	low	5	0
gentamicin	low	2	0
hexadecanesulfonyl fluoride	low	1	0
hydroxychloroquine	low	1	0
lamotrigine	medium	3	2
2-(4-morpholinyl)-8-phenyl-4h-1-benzopyran-4-one	low	1	0
memantine	low	2	0
vitamin k 3	low	1	0
nicardipine	low	2	0
nifedipine	low	1	0
nimodipine	low	1	0
aminosalicylic acid	low	1	0
phenobarbital	medium	1	1
phenylmethylsulfonyl fluoride	low	1	0
piracetam	low	2	0
pirenzepine	medium	1	1
potassium chloride	low	1	0
propofol	low	1	0
risperidone	medium	2	1
s-methylisothiopseudouronium	low	1	0
zonisamide	low	1	0
corticosterone	low	1	0
prednisolone	medium	1	1
thymidine	low	2	0
dextroamphetamine	low	1	0
prednisone	low	1	0
serine	low	2	0
chloramphenicol	low	2	0
aspartic acid	low	6	0
glutamine	low	6	0
lysine	low	8	0
sucrose	low	1	0
adenosine diphosphate	low	2	0
levodopa	low	1	0
cysteamine	medium	4	1
adenosine monophosphate	low	2	0
leucine	low	1	0
methionine	low	6	0
cycloheximide	low	1	0
asparagine	low	2	0
threonine	low	2	0
tryptophan	low	1	0
arginine	low	7	0
methylamine	low	1	0
4-phenylenediamine	low	1	0
pyrroles	low	1	0
thiophenes	low	1	0
dodecyl sulfate	low	1	0
isoxazoles	low	1	0
oxazoles	low	1	0
thiazoles	low	1	0
hydrazine	low	1	0
flurothyl	low	1	0
citrulline	low	1	0
alpha-aminopyridine	low	4	0
medroxyprogesterone	low	1	0
dicyclohexylcarbodiimide	low	4	0
acetylcysteine	medium	5	1
citiolone	low	1	0
d-alpha tocopherol	low	12	0
tocopherols	low	1	0
fluorescein-5-isothiocyanate	low	1	0
mannose	low	7	0
manganese	low	2	0
osmium	low	1	0
tetradecanoylphorbol acetate	low	1	0
1-deoxynojirimycin	low	1	0
daunorubicin	low	1	0
phenyl acetate	low	2	0
cetylpyridinium chloride anhydrous	low	1	0
isothiuronium	low	1	0
transferrin	low	2	0
glutamic acid	low	13	0
s-adenosylmethionine	low	1	0
etoposide	low	3	0
bezafibrate	low	1	0
ng-nitroarginine methyl ester	low	1	0
propiconazole	low	1	0
fomesafen	low	1	0
flupirtine	low	3	0
fura-2	low	1	0
vanadates	low	1	0
thiazolyl blue	low	1	0
n-acetylaspartic acid	low	6	0
bromosuccinimide	low	1	0
1,7-phenanthroline	low	1	0
fluorodeoxyglucose f18	low	4	0
5-fluoroorotic acid	low	1	0
leupeptin	low	1	0
delta-tocopherol	low	1	0
mor-14	low	1	0
1-(4'-nitrophenyl)-2-aminopropane-1,3-diol	low	1	0
n-tert-butylhydroxylamine	low	3	0
cobalt	low	1	0
fingolimod hydrochloride	low	2	0
deoxyglucose	low	4	0
1-((3,5-dichloro)-2,6-dihydroxy-4-methoxyphenyl)-1-hexanone	low	12	0
e 64	low	1	0
alanyl-alanyl-phenylalanine chloromethyl ketone	low	1	0
proline	low	2	0
carbodiimides	low	1	0
biotin	low	1	0
angiotensin ii	low	1	0
taurochenodeoxycholic acid	low	1	0
bortezomib	low	2	0
leupeptins	low	1	0
lithium chloride	low	1	0
glycogen	low	3	0
n-acetylneuraminic acid	low	2	0
mannose-6-phosphate	low	3	0
glucosamine	low	2	0
mevalonic acid	low	1	0
trimethyllysine	low	4	0
linezolid	low	1	0
arachidonic acid	low	1	0
resveratrol	low	4	0
tacrolimus	medium	1	1
mycophenolic acid	medium	4	1
riboflavin	low	1	0
isomethyleugenol	low	7	0
stilbenes	low	4	0
sorbic acid	low	1	0
cannabidiol	low	1	0
palmitoyl coenzyme a	low	3	0
flunarizine	low	2	0
curcumin	low	1	0
fumonisin b1	low	1	0
tamoxifen	low	2	0
cholecystokinin pentapeptide	low	1	0
sodium dodecyl sulfate	low	1	0
alpha-chymotrypsin	low	1	0
myelin basic protein	low	3	0
sphingosine	low	2	0
luteolin	low	1	0
psychosine	low	1	0
hymecromone	low	1	0
alpha-linolenic acid	low	1	0
coenzyme q10	low	1	0
4-hydroxy-2-nonenal	low	5	0
levetiracetam	low	2	0
sirolimus	low	1	0
brefeldin a	low	1	0
fenretinide	low	1	0
casein kinase ii	low	1	0
cysteine	low	4	0
pepstatin	low	3	0
n-acetylsphingosine	low	1	0
selenium	low	7	0
tellurium	low	1	0
mevalonolactone	low	1	0
dolichols	low	25	0
bafilomycin a1	low	1	0
cdw17 antigen	low	1	0
i(3)so3-galactosylceramide	low	3	0
beta-escin	low	1	0
staurosporine	low	2	0
phosphocreatine	low	1	0
sincalide	low	1	0
egis-8332	low	1	0
ursodoxicoltaurine	low	1	0
g(m2) ganglioside	low	1	0
perampanel	low	1	0
g(m1) ganglioside	low	1	0
cystathionine	low	1	0
alpha-synuclein	low	6	0
oxadiazoles	low	2	0
ptc 124	low	2	0
losartan potassium	low	1	0
technetium tc 99m exametazime	medium	3	1
calcimycin	low	1	0
acid phosphatase	low	3	0
nad	low	2	0
cholecystokinin	low	1	0
oligonucleotides	low	2	0
phosphatidylcholines	low	4	0
dihydroceramide	low	1	0
ubiquinone	low	3	0
dolichol monophosphate	low	2	0
dolichol pyrophosphate	low	1	0
quetiapine fumarate	medium	1	1
pexidartinib	low	1	0
cysteamine-s-phosphate	low	2	0
ganglioside, gd1a	low	1	0
glycolipids	low	8	0
interleukin-8	low	1	0
ascorbic acid	low	4	0
minocycline	low	2	0
teriflunomide	low	2	0
ark 62-62	low	1	0
globotriaosylceramide	low	1	0
ganglioside gm1alpha	low	1	0
oligomycins	low	1	0
g(m3) ganglioside	low	2	0
benzyloxycarbonylvalyl-alanyl-aspartyl fluoromethyl ketone	low	1	0
lipofectamine	low	1	0
nusinersen	low	1	0
cyclic gmp	low	1	0
deoxyguanosine	low	1	0
guanine	low	1	0
3-methyladenine	low	1	0
olanzapine	medium	1	1
allopurinol	low	1	0
8-hydroxy-2'-deoxyguanosine	low	1	0
eye	low	14	0
concanavalin a	low	4	0
metallothionein	low	2	0
2',7'-bis(carboxyethyl)-5(6)-carboxyfluorescein	low	1	0

Protein Targets (2,107)

Protein	Potency Measurements	Inhibition Measurements	Activation Measurements	Drugs
Chain A, Beta-lactamase	15	0	0	15
Chain A, 2-oxoglutarate Oxygenase	21	0	0	21
glp-1 receptor, partial	14	0	0	14
thioredoxin reductase	38	0	0	38
lysosomal alpha-glucosidase preproprotein	11	0	0	11
muscleblind-like protein 1 isoform 1	10	0	0	10
Neuronal acetylcholine receptor subunit alpha-4	3	5	0	8
Neuronal acetylcholine receptor subunit beta-2	3	5	0	8
Chain B, pheromone binding protein	0	0	1	1
Chain A, pheromone binding protein	0	0	1	1
Chain A, JmjC domain-containing histone demethylation protein 3A	19	0	0	19
Chain A, RNA-directed RNA polymerase NS5	0	1	0	1
acid sphingomyelinase	5	0	0	5
USP1 protein, partial	33	0	0	33
TDP1 protein	60	0	0	60
vitamin D3 receptor isoform VDRA	26	0	0	26
importin subunit beta-1 isoform 1	13	0	0	13
flap endonuclease 1	21	0	0	21
serine/threonine-protein kinase PLK1	4	0	0	4
snurportin-1	13	0	0	13
peptidyl-prolyl cis-trans isomerase NIMA-interacting 1	12	0	0	12
GTP-binding nuclear protein Ran isoform 1	8	0	0	8
DNA polymerase eta isoform 1	6	0	0	6
DNA polymerase iota isoform a (long)	25	0	0	25
urokinase-type plasminogen activator precursor	14	0	0	14
plasminogen precursor	14	0	0	14
urokinase plasminogen activator surface receptor precursor	14	0	0	14
geminin	54	0	0	54
DNA polymerase kappa isoform 1	22	0	0	22
fibroblast growth factor 22 isoform 1 precursor	0	0	0	1
Mitogen-activated protein kinase 13	0	1	0	1
Beta-lactamase	0	2	0	2
Transthyretin	0	2	4	6
Fatty acid-binding protein, intestinal	0	4	2	6
Fatty acid-binding protein, adipocyte	0	4	3	7
Cyclin-A2	0	2	0	2
Cannabinoid receptor 1	0	3	2	5
Cyclin-dependent kinase 2	0	3	3	6
Choline O-acetyltransferase	0	2	0	2
Mitogen-activated protein kinase 12	0	1	0	1
Guanine nucleotide-binding protein G	11	0	0	11
Fatty acid-binding protein 5	0	3	2	5
Fatty acid-binding protein 5	0	0	2	2
Mitogen-activated protein kinase 11	0	1	2	3
Mitogen-activated protein kinase 14	0	2	2	4
Chain A, MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASE	30	0	0	30
glucocerebrosidase	13	0	0	13
Alpha-mannosidase	0	1	0	1
alpha-galactosidase	6	0	0	6
Trehalase	0	1	0	1
Trehalase	0	1	0	1
Maltase-glucoamylase, intestinal	0	2	0	2
Trehalase	0	2	0	2
Lysosomal acid glucosylceramidase	0	3	1	4
Alpha-galactosidase A	0	1	0	1
Alpha-glucosidase MAL62	0	1	0	1
Lactase-phlorizin hydrolase	0	1	0	1
Lysosomal alpha-glucosidase	0	3	0	3
Beta-glucosidase A	0	1	0	1
Sucrase-isomaltase, intestinal	0	1	0	1
Alpha-1B adrenergic receptor	0	14	0	14
Sucrase-isomaltase, intestinal	0	3	0	3
Alpha-1D adrenergic receptor	0	6	0	6
Beta-glucosidase	0	1	0	1
Protein-lysine 6-oxidase	0	3	0	3
Alpha-mannosidase 2	0	2	0	2
Glycogen debranching enzyme	0	1	0	1
Glycogen debranching enzyme	0	1	0	1
Alpha-glucosidase MAL32	0	1	0	1
Alpha-1A adrenergic receptor	0	15	0	15
Oligo-1,6-glucosidase IMA1	0	1	0	1
Alpha-glucosidase MAL12	0	3	0	3
Oxysterols receptor LXR-beta	0	1	0	1
Spike glycoprotein	21	1	6	28
Alpha-amylase	0	1	0	1
Trehalose synthase/amylase TreS	0	1	0	1
Lactase-phlorizin hydrolase	0	2	0	2
Oxysterols receptor LXR-alpha	0	1	0	1
Neutral alpha-glucosidase AB	0	2	0	2
Ceramide glucosyltransferase	0	1	0	1
Lysosomal acid glucosylceramidase	0	1	0	1
Probable maltase-glucoamylase 2	0	1	0	1
Beta-glucosidase	0	1	0	1
Lysosomal alpha-glucosidase	0	2	0	2
Cytosolic beta-glucosidase	0	1	0	1
Non-lysosomal glucosylceramidase	0	1	0	1
Putative alpha-glucosidase	0	1	0	1
Chain A, TYROSYL-DNA PHOSPHODIESTERASE	25	0	0	25
Chain A, Putative fructose-1,6-bisphosphate aldolase	9	0	0	9
Luciferase	23	0	0	23
endonuclease IV	8	0	0	8
acetylcholinesterase	21	0	0	21
15-lipoxygenase, partial	14	0	0	14
pregnane X receptor	11	0	0	11
phosphopantetheinyl transferase	30	0	0	30
hypoxia-inducible factor 1 alpha subunit	21	0	0	21
RAR-related orphan receptor gamma	45	0	0	45
ATAD5 protein, partial	25	0	0	25
Fumarate hydratase	12	0	0	12
NFKB1 protein, partial	13	0	0	13
GLI family zinc finger 3	45	0	0	45
Microtubule-associated protein tau	27	0	0	27
Thrombopoietin	8	0	0	8
AR protein	66	0	0	66
Smad3	17	0	0	17
hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)	18	0	0	18
thyroid stimulating hormone receptor	20	0	0	20
estrogen receptor 2 (ER beta)	27	0	0	27
nuclear receptor subfamily 1, group I, member 3	38	0	0	38
progesterone receptor	36	0	0	36
regulator of G-protein signaling 4	26	0	0	26
nonstructural protein 1	9	0	0	9
nonstructural protein 1	0	2	0	2
glucocorticoid receptor [Homo sapiens]	48	0	0	48
retinoic acid nuclear receptor alpha variant 1	51	0	0	51
retinoid X nuclear receptor alpha	36	0	0	36
estrogen-related nuclear receptor alpha	57	0	0	57
farnesoid X nuclear receptor	35	0	0	35
pregnane X nuclear receptor	42	0	0	42
estrogen nuclear receptor alpha	72	0	0	72
polyprotein	12	0	0	12
67.9K protein	19	0	0	19
Parkin	12	0	0	12
bromodomain adjacent to zinc finger domain 2B	15	0	0	15
peroxisome proliferator-activated receptor delta	32	0	0	32
peroxisome proliferator activated receptor gamma	37	0	0	37
vitamin D (1,25- dihydroxyvitamin D3) receptor	36	0	0	36
arylsulfatase A	25	0	0	25
heat shock protein 90	0	0	1	1
IDH1	18	0	0	18
euchromatic histone-lysine N-methyltransferase 2	64	0	0	64
TPA: protein transporter TIM10	0	2	0	2
TPA: protein transporter TIM23	0	1	0	1
aryl hydrocarbon receptor	25	0	0	25
cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a	38	0	0	38
v-jun sarcoma virus 17 oncogene homolog (avian)	25	0	0	25
Histone H2A.x	23	0	0	23
Caspase-7	8	0	0	8
cytochrome P450 2D6 isoform 1	14	0	0	14
peripheral myelin protein 22 isoform 1	15	0	0	15
cellular tumor antigen p53 isoform a	15	0	0	15
tumor necrosis factor	3	0	0	3
runt-related transcription factor 1 isoform AML1b	2	0	0	2
chromobox protein homolog 1	38	0	0	38
thyroid hormone receptor beta isoform a	20	0	0	20
nuclear factor erythroid 2-related factor 2 isoform 2	20	0	0	20
caspase-3	8	0	0	8
thyroid hormone receptor beta isoform 2	46	0	0	46
histone deacetylase 9 isoform 3	8	0	0	8
heat shock protein beta-1	26	0	0	26
core-binding factor subunit beta isoform 2	2	0	0	2
huntingtin isoform 2	10	0	0	10
serine/threonine-protein kinase mTOR isoform 1	14	0	0	14
heat shock protein HSP 90-alpha isoform 2	0	0	0	4
nuclear factor erythroid 2-related factor 2 isoform 1	46	0	0	46
nuclear receptor ROR-gamma isoform 1	27	0	0	27
survival motor neuron protein isoform d	22	0	0	22
cytochrome P450 3A4 isoform 1	26	0	0	26
exodeoxyribonuclease V subunit RecD	0	1	0	1
exodeoxyribonuclease V subunit RecB	0	1	0	1
exodeoxyribonuclease V subunit RecC	0	1	0	1
lamin isoform A-delta10	52	0	0	52
Gamma-aminobutyric acid receptor subunit pi	26	7	1	34
Galanin receptor type 2	0	1	0	1
Voltage-dependent calcium channel gamma-2 subunit	28	0	0	28
Carboxypeptidase A1	0	1	0	1
Thermolysin	0	1	0	1
Cellular tumor antigen p53	50	0	0	50
Amyloid-beta precursor protein	2	5	1	9
Integrin beta-3	12	0	1	13
Integrin alpha-IIb	12	0	1	13
Gamma-aminobutyric acid receptor subunit beta-1	26	7	1	34
Gamma-aminobutyric acid receptor subunit delta	26	7	1	34
Gamma-aminobutyric acid receptor subunit gamma-2	26	7	3	36
Glutamate receptor 2	28	3	2	33
Gamma-aminobutyric acid receptor subunit alpha-5	26	7	1	34
Gamma-aminobutyric acid receptor subunit alpha-3	26	7	1	34
Gamma-aminobutyric acid receptor subunit gamma-1	26	7	1	34
Gamma-aminobutyric acid receptor subunit alpha-2	26	7	1	34
Gamma-aminobutyric acid receptor subunit alpha-4	26	7	1	34
Gamma-aminobutyric acid receptor subunit gamma-3	26	7	1	34
Gamma-aminobutyric acid receptor subunit alpha-6	26	7	1	34
C-C chemokine receptor type 1	0	1	1	2
Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha	0	1	0	1
Protein farnesyltransferase subunit beta	0	1	0	1
D(1A) dopamine receptor	9	0	0	9
Nuclear receptor ROR-gamma	11	0	0	11
C-C chemokine receptor type 5	0	1	1	2
C-C chemokine receptor type 8	0	0	1	1
Gamma-aminobutyric acid receptor subunit alpha-1	26	7	3	36
Gamma-aminobutyric acid receptor subunit beta-3	26	7	1	34
Gamma-aminobutyric acid receptor subunit beta-2	26	7	3	36
TAR DNA-binding protein 43	15	0	0	15
Metallo-beta-lactamase VIM-13	0	1	0	1
GABA theta subunit	26	7	1	34
ATPase family AAA domain-containing protein 5	26	0	0	26
Ataxin-2	31	0	0	31
Gamma-aminobutyric acid receptor subunit epsilon	26	7	1	34
Snake venom metalloproteinase neuwiedase	0	1	0	1
Collagenase ColG	0	1	0	1
Beta-lactamase VIM-1	0	1	0	1
heat shock protein 90, putative	0	0	0	4
ATP-dependent phosphofructokinase	31	0	0	31
Chain A, Proto-oncogene serine/threonine-protein kinase Pim-1	0	1	0	1
Chain A, Proto-oncogene serine/threonine-protein kinase Pim-1	0	1	0	1
Chain A, HADH2 protein	18	0	0	18
Chain B, HADH2 protein	18	0	0	18
Chain A, Cruzipain	11	0	0	11
Chain A, Methyltransferase Wbdd	0	1	0	1
aldehyde dehydrogenase 1 family, member A1	28	0	0	28
EWS/FLI fusion protein	29	0	0	30
cytochrome P450 2C19 precursor	12	0	0	12
cytochrome P450 2C9 precursor	10	0	0	10
M-phase phosphoprotein 8	15	0	0	15
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform	0	1	0	2
cGMP-dependent 3',5'-cyclic phosphodiesterase	0	1	0	1
Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha	0	1	0	1
Serine/threonine-protein kinase PLK4	0	1	2	3
Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta	0	1	0	1
Polyunsaturated fatty acid lipoxygenase ALOX15B	12	0	0	12
Bromodomain-containing protein 4	0	1	0	1
5-hydroxytryptamine receptor 4	0	22	2	24
cGMP-specific 3',5'-cyclic phosphodiesterase	0	1	0	1
Cytochrome P450 1A2	0	8	0	9
Serine/threonine-protein kinase pim-1	0	2	2	4
Casein kinase II subunit alpha'	0	4	2	6
Proteinase-activated receptor 1	0	0	0	1
Bromodomain-containing protein 2	0	1	0	1
Phosphatidylinositol 3-kinase regulatory subunit alpha	0	1	0	2
5-hydroxytryptamine receptor 2A	0	16	0	16
5-hydroxytryptamine receptor 2C	0	23	0	23
Sodium-dependent serotonin transporter	0	4	1	5
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform	0	1	0	1
Type-1 angiotensin II receptor	0	1	0	1
5-hydroxytryptamine receptor 2B	0	19	0	19
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform	0	2	0	3
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform	0	1	0	1
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform	0	1	0	3
Serine/threonine-protein kinase mTOR	0	4	1	5
Serine/threonine-protein kinase mTOR	0	1	0	1
Histamine H2 receptor	17	0	0	17
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform	0	1	0	2
Glycogen synthase kinase-3 beta	0	4	3	7
Serine/threonine-protein kinase PLK1	0	2	1	3
Casein kinase II subunit beta	0	4	0	4
Casein kinase II subunit alpha	0	4	0	4
DNA-dependent protein kinase catalytic subunit	0	2	0	2
Mu-type opioid receptor	0	4	1	5
Serine-protein kinase ATM	0	1	0	1
cGMP-inhibited 3',5'-cyclic phosphodiesterase B	0	3	0	3
Serine/threonine-protein kinase ATR	0	1	0	1
cGMP-inhibited 3',5'-cyclic phosphodiesterase A	0	3	0	3
Bromodomain-containing protein 3	0	1	0	1
Serine/threonine-protein kinase pim-3	0	1	0	1
Phosphoinositide 3-kinase regulatory subunit 5	0	1	0	1
Serine/threonine-protein kinase PLK3	0	2	0	2
Serine/threonine-protein kinase PLK2	0	1	0	1
Chain A, DNA-3-methyladenine glycosylase I	0	0	1	1
Chain A, DNA-3-METHYLADENINE GLYCOSYLASE I	0	0	1	1
Chain A, Dna-3-methyladenine Glycosylase I	0	0	1	1
Transient receptor potential cation channel subfamily A member 1	0	2	3	5
cytochrome P450 family 3 subfamily A polypeptide 4	28	0	0	28
G	26	0	0	26
cytochrome P450 2D6	21	0	0	21
thyroid stimulating hormone receptor	23	0	0	23
nuclear receptor subfamily 1, group I, member 2	7	0	0	7
peripheral myelin protein 22	25	0	0	25
Interferon beta	37	0	0	37
HLA class I histocompatibility antigen, B alpha chain	26	0	0	26
Inositol hexakisphosphate kinase 1	26	0	0	26
cytochrome P450 2C9, partial	26	0	0	26
apical membrane antigen 1, AMA1	8	0	0	8
Janus kinase 2 (a protein tyrosine kinase)	0	1	0	1
transcriptional regulator ERG isoform 3	9	0	0	9
Chain A, Avidin	0	0	2	2
Chain A, Avidin	0	0	2	2
Chain B, Avidin	0	0	2	2
Free fatty acid receptor 3	0	0	1	1
Free fatty acid receptor 2	0	1	1	2
Tyrosine-protein kinase Lck	0	3	3	6
Tyrosine-protein kinase Fyn	0	3	3	6
Fibrinogen C domain-containing protein 1	0	1	0	1
Chain A, ATP-DEPENDENT DNA HELICASE Q1	11	0	0	11
dopamine D1 receptor	4	0	0	4
Bloom syndrome protein isoform 1	30	0	0	30
D(1A) dopamine receptor	16	0	0	16
muscarinic acetylcholine receptor M1	17	0	0	17
Histone deacetylase 3	0	6	0	6
Solute carrier family 22 member 6	0	1	0	1
Histone deacetylase 4	0	5	0	5
Histone deacetylase 1	0	8	0	8
Histone deacetylase 7	0	5	0	5
Histone deacetylase 2	0	7	0	7
Polyamine deacetylase HDAC10	0	5	0	5
Histone deacetylase 11	0	5	0	5
Histone deacetylase 8	0	8	0	8
Histone deacetylase 6	0	7	0	7
Histone deacetylase 9	0	5	0	5
Histone deacetylase 5	0	5	0	5
Chain A, MTA/SAH nucleosidase	0	1	0	1
Chain A, Ribosome-inactivating protein alpha-trichosanthin	0	0	1	1
Chain A, Ricin A chain	0	0	1	1
Chain A, Ribosome-inactivating protein 3	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
tumor susceptibility gene 101 protein	4	0	0	4
Bile salt export pump	0	45	0	47
Cyclin-dependent kinase 1	0	2	2	4
Heat shock protein HSP 90-beta	0	2	1	4
Xanthine dehydrogenase/oxidase	0	5	0	5
Protein mono-ADP-ribosyltransferase PARP15	0	2	0	2
Leucine-rich repeat serine/threonine-protein kinase 2	0	2	0	2
Chain A, Heat Shock Protein 90	0	0	1	1
Chain A, GLUTAMINE PHOSPHORIBOSYLPYROPHOSPHATE AMIDOTRANSFERASE	0	0	1	1
Chain B, GLUTAMINE PHOSPHORIBOSYLPYROPHOSPHATE AMIDOTRANSFERASE	0	0	1	1
Chain A, EOSINOPHIL-DERIVED NEUROTOXIN	0	1	0	1
Chain A, EOSINOPHIL-DERIVED NEUROTOXIN	0	1	0	1
Chain A, EOSINOPHIL-DERIVED NEUROTOXIN	0	1	0	1
Chain A, Myosin Ie Heavy Chain	0	0	1	1
Chain A, Preprotein translocase secA	0	0	1	1
Chain A, Ribonuclease pancreatic	0	1	0	1
Chain A, Ribonuclease pancreatic	0	1	0	1
Chain A, Ribonuclease pancreatic	0	1	0	1
Chain A, Ribonuclease pancreatic	0	1	0	1
Chain A, Ribonuclease pancreatic	0	1	0	1
Chain A, Phosphoribosylformylglycinamidine synthase	0	1	0	1
Chain A, nucleoside diphosphate kinase A	0	0	1	1
Chain B, nucleoside diphosphate kinase A	0	0	1	1
Chain D, DNA polymerase III subunit gamma	0	0	1	1
Chain D, DNA polymerase III subunit gamma	0	0	1	1
Chain A [Pyruvate dehydrogenase [lipoamide]] kinase isozyme 3	0	0	1	1
Chain A [Pyruvate dehydrogenase [lipoamide]] kinase isozyme 3	0	0	1	1
Chain A, Kinesin-like protein KIF11	0	1	0	1
HPr kinase/phosphorylase	0	0	1	1
Mitogen-activated protein kinase kinase kinase 7	0	0	2	2
ATP-dependent molecular chaperone HSP82	0	0	0	1
Heat shock protein HSP 90-alpha	0	1	2	4
2-dehydropantoate 2-reductase	0	2	2	4
Heat shock 70 kDa protein 1A	0	1	1	2
Endoplasmic reticulum chaperone BiP	0	0	1	1
Heat shock cognate 71 kDa protein	0	0	1	1
Pyruvate kinase PKM	0	0	0	1
Pyruvate kinase PKLR	0	0	0	1
Endoplasmin	0	0	0	1
Heat shock cognate 71 kDa protein	0	0	1	1
5'-nucleotidase	0	1	0	1
Mu-type opioid receptor	0	8	2	10
Delta-type opioid receptor	0	6	2	8
Kappa-type opioid receptor	0	8	1	9
Endoplasmin	0	1	1	2
P2Y purinoceptor 2	0	0	2	2
Phosphatidylinositol 4-kinase alpha	0	3	0	3
P2X purinoceptor 1	0	0	1	1
P2Y purinoceptor 1	0	0	2	2
P2Y purinoceptor 1	0	0	2	2
P2X purinoceptor 1	0	0	1	1
P2X purinoceptor 4	0	0	1	1
P2X purinoceptor 5	0	0	1	1
P2X purinoceptor 6	0	0	1	1
P2X purinoceptor 3	0	1	1	2
Inositol monophosphatase 1	10	0	0	10
Heat shock protein 75 kDa, mitochondrial	0	1	0	1
P2Y purinoceptor 6	0	0	1	1
Phosphatidylinositol 4-kinase type 2-beta	0	3	0	3
P2Y purinoceptor 11	0	0	2	2
Phosphatidylinositol 4-kinase type 2-alpha	0	3	0	3
P2Y purinoceptor 12	0	0	1	1
Sensor protein kinase WalK	0	1	0	1
Phosphatidylinositol 4-kinase beta	0	3	0	3
P2X purinoceptor 2	0	0	1	1
Chain A, Glycogen Phosphorylase B	0	0	1	1
Chain B, Glycogen Phosphorylase B	0	0	1	1
Chain A, ADP-dependent glucokinase	0	1	0	1
Chain A, Ribonuclease pancreatic	0	1	0	1
Chain A, Ribonuclease pancreatic	0	1	0	1
Chain A, phosphodiesterase-nucleotide pyrophosphatase	0	1	0	1
Chain A, GLYCOGEN PHOSPHORYLASE B	0	0	1	1
Chain B, GLYCOGEN PHOSPHORYLASE B	0	0	1	1
Chain A, GLYCOGEN PHOSPHORYLASE B	0	0	1	1
2'-deoxynucleoside 5'-phosphate N-hydrolase 1	0	1	0	1
2'-deoxynucleoside 5'-phosphate N-hydrolase 1	0	1	0	1
5'-AMP-activated protein kinase subunit beta-2	0	0	1	1
Transient receptor potential cation channel subfamily M member 2	0	1	0	1
Alcohol dehydrogenase E chain	0	1	0	1
Alcohol dehydrogenase S chain	0	1	0	1
L-lactate dehydrogenase A chain	0	3	1	4
Adenylate kinase isoenzyme 1	0	0	0	1
Fructose-1,6-bisphosphatase 1	0	1	0	1
Alkaline phosphatase, tissue-nonspecific isozyme	0	2	0	3
Fructose-1,6-bisphosphatase 1	0	1	0	1
Inosine-5'-monophosphate dehydrogenase	0	1	0	1
Cytochrome P450 2C9	0	14	0	15
Proto-oncogene tyrosine-protein kinase Src	0	1	2	3
Amine oxidase [flavin-containing] B	0	4	0	4
5'-nucleotidase	0	0	0	1
Adenylate kinase 2, mitochondrial	0	1	0	2
GTP:AMP phosphotransferase AK3, mitochondrial	0	0	0	1
Adenosine receptor A1	0	4	1	5
Adenylate kinase isoenzyme 1	0	1	0	2
5'-AMP-activated protein kinase subunit gamma-1	0	0	4	4
5'-AMP-activated protein kinase catalytic subunit alpha-2	0	0	1	1
Adenylate kinase 2, mitochondrial	0	0	2	3
Glycine--tRNA ligase	0	1	0	1
5'-AMP-activated protein kinase catalytic subunit alpha-1	0	0	4	4
Adenosine deaminase-like protein	0	0	0	1
Protease	0	2	1	3
Histamine H3 receptor	0	1	0	1
5'-AMP-activated protein kinase subunit gamma-3	0	0	1	1
5'-AMP-activated protein kinase subunit gamma-2	0	0	3	3
5'-AMP-activated protein kinase subunit beta-1	0	0	2	2
interleukin 8	9	0	0	9
ras-related protein Rab-9A	13	0	0	13
ATP-binding cassette sub-family C member 3	0	31	0	31
Multidrug resistance-associated protein 4	0	32	0	33
Polyphenol oxidase 2	0	3	0	4
Hypoxanthine-guanine phosphoribosyltransferase	0	0	0	2
Xanthine dehydrogenase/oxidase [Includes: Xanthine dehydrogenase	0	1	0	1
Adenosine receptor A2a	0	3	1	4
Nuclear receptor ROR-gamma	0	1	0	1
Xanthine dehydrogenase/oxidase	0	4	1	7
Purine nucleoside phosphorylase	0	0	1	1
Canalicular multispecific organic anion transporter 1	0	30	0	31
Shiga toxin subunit A	0	2	0	2
Histamine H3 receptor	0	1	0	1
Botulinum neurotoxin type A	0	1	0	1
Neutrophil cytosol factor 1	0	1	0	1
Nitric oxide synthase, endothelial	0	3	0	3
Nitric oxide synthase, brain	0	4	0	5
Nitric oxide synthase, brain	0	2	0	3
Nitric oxide synthase, inducible	0	3	1	6
Kappa-type opioid receptor	0	4	1	5
Tyrosine-protein kinase	0	0	1	1
Methylcytosine dioxygenase TET2	0	2	1	3
WRN	3	0	0	3
SMAD family member 2	19	0	0	19
GLS protein	24	0	0	24
SMAD family member 3	19	0	0	19
thioredoxin glutathione reductase	11	0	0	11
activating transcription factor 6	27	0	0	27
nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105), isoform CRA_a	23	0	0	23
15-hydroxyprostaglandin dehydrogenase [NAD(+)] isoform 1	17	0	0	17
phospholipase A2 precursor	0	1	0	1
cysteine protease ATG4B isoform a	0	1	0	1
lethal(3)malignant brain tumor-like protein 1 isoform I	5	0	0	5
histone acetyltransferase KAT2A isoform 1	19	0	0	19
DNA dC->dU-editing enzyme APOBEC-3G isoform 1	5	1	0	6
DNA dC->dU-editing enzyme APOBEC-3F isoform a	2	0	0	2
Free fatty acid receptor 1	0	0	1	1
Prostaglandin G/H synthase 1	0	2	0	3
Nuclear receptor subfamily 1 group I member 2	0	0	6	6
Trypsin	0	3	0	3
Coagulation factor VII	0	2	0	2
Aromatase	0	5	0	5
Tissue factor	0	4	0	4
Prostaglandin G/H synthase 1	0	5	0	5
Peroxisome proliferator-activated receptor gamma	0	1	6	7
Prostaglandin G/H synthase 2	0	3	0	4
Free fatty acid receptor 4	0	0	1	1
microphthalmia-associated transcription factor isoform 9	0	1	0	1
Carbonic anhydrase 1	0	10	0	17
Carbonic anhydrase 2	0	11	2	20
Tyrosine-protein phosphatase non-receptor type 1	0	3	1	4
Chain A, Ferritin light chain	19	0	0	19
NEDD8-activating enzyme E1 regulatory subunit isoform a	0	1	0	1
NEDD8-conjugating enzyme Ubc12	0	1	0	1
Voltage-dependent L-type calcium channel subunit alpha-1C	0	6	0	6
Potassium channel subfamily K member 2	0	1	4	5
ATP-dependent translocase ABCB1	0	15	2	29
Alpha-2A adrenergic receptor	0	16	0	16
Alpha-2C adrenergic receptor	0	13	0	13
Alpha-2B adrenergic receptor	0	4	0	4
Voltage-dependent L-type calcium channel subunit alpha-1C	0	6	0	7
Alpha-2C adrenergic receptor	0	4	0	4
Alpha-2A adrenergic receptor	0	4	0	4
Alpha-1D adrenergic receptor	0	15	0	15
Alpha-1A adrenergic receptor	0	4	0	4
Alpha-1B adrenergic receptor	0	3	0	3
5-hydroxytryptamine receptor 6	0	10	0	10
Sodium-dependent dopamine transporter	0	13	1	14
Voltage-dependent L-type calcium channel subunit alpha-1C	0	10	0	11
Potassium channel subfamily K member 2	0	3	0	3
Atrial natriuretic peptide receptor 3	0	1	0	1
Type-1A angiotensin II receptor	0	3	1	4
Type-1 angiotensin II receptor	0	0	1	1
Type-1B angiotensin II receptor	0	4	0	4
Type-1 angiotensin II receptor	0	2	2	4
Type-2 angiotensin II receptor	0	3	0	3
Type-2 angiotensin II receptor	0	2	0	2
Chain A, ADIPOCYTE LIPID-BINDING PROTEIN	0	0	1	1
Chain A, SERUM ALBUMIN	0	0	1	1
Chain A, SERUM ALBUMIN	0	0	1	1
heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)	11	0	0	11
ubiquitin carboxyl-terminal hydrolase 2 isoform a	8	0	0	8
caspase-1 isoform alpha precursor	5	0	0	5
Fatty-acid amide hydrolase 1	0	4	0	4
60 kDa chaperonin	0	4	0	4
60 kDa heat shock protein, mitochondrial	0	4	0	4
Prostaglandin G/H synthase 2	0	4	1	6
Nuclear receptor subfamily 4 group A member 2	0	0	2	2
10 kDa heat shock protein, mitochondrial	0	4	0	4
Calmodulin	0	0	0	1
Disintegrin and metalloproteinase domain-containing protein 17	6	0	0	6
Solute carrier organic anion transporter family member 2A1	0	0	0	1
Thiosulfate sulfurtransferase	0	4	0	4
Lanosterol 14-alpha demethylase	0	1	0	1
60 kDa chaperonin	0	4	0	4
10 kDa chaperonin	0	4	0	4
Solute carrier organic anion transporter family member 1B3	0	5	0	6
Cytosolic phospholipase A2 gamma	0	1	0	1
Transient receptor potential cation channel subfamily V member 2	0	3	1	4
Solute carrier organic anion transporter family member 1B1	0	7	0	7
Chain E, LYSINE, ARGININE, ORNITHINE-BINDING PROTEIN	0	0	1	1
Chain E, LYSINE, ARGININE, ORNITHINE-BINDING PROTEIN	0	0	1	1
Chain E, LYSINE, ARGININE, ORNITHINE-BINDING PROTEIN	0	0	1	1
lethal factor (plasmid)	19	0	0	19
Cytochrome P450 3A4	0	17	0	19
Nitric oxide synthase, endothelial	0	1	0	3
Nitric oxide synthase, inducible	0	2	0	3
Cationic amino acid transporter 3	0	2	0	2
Chain A, Hyaluronidase, phage associated	0	1	0	1
Pancreatic alpha-amylase	0	2	0	2
Albumin	0	1	0	1
Urease	0	1	0	1
Prolyl 4-hydroxylase subunit alpha-1	0	0	0	1
Tyrosinase	0	5	0	5
Alpha-2B adrenergic receptor	0	13	1	14
Hyaluronate lyase	0	1	0	1
Prolyl hydroxylase EGLN2	0	0	0	1
Egl nine homolog 1	0	1	1	3
Prolyl hydroxylase EGLN3	0	0	0	1
Hypoxia-inducible factor 1-alpha inhibitor	0	0	0	1
Solute carrier family 23 member 1	0	1	0	1
Neutral amino acid transporter A	0	4	0	4
Neutral amino acid transporter B(0)	0	4	0	4
Carbonic anhydrase-like protein, putative	0	0	0	6
Amino acid transporter	0	4	0	4
Metabotropic glutamate receptor 6	0	1	2	4
Excitatory amino acid transporter 4	0	2	0	2
Glutamate transporter homolog	0	0	1	1
N(4)-(beta-N-acetylglucosaminyl)-L-asparaginase	0	2	0	2
5-hydroxytryptamine receptor 1D	0	0	0	1
Glutamate receptor ionotropic, NMDA 1	0	6	2	11
Excitatory amino acid transporter 1	0	3	0	4
Excitatory amino acid transporter 2	0	3	0	4
Excitatory amino acid transporter 3	0	3	0	4
Glutamate receptor ionotropic, NMDA 2A	0	5	2	10
Glutamate receptor ionotropic, NMDA 2B	0	5	2	10
Glutamate receptor ionotropic, NMDA 2C	0	5	2	10
Metabotropic glutamate receptor 1	0	1	2	4
Metabotropic glutamate receptor 2	0	1	2	4
Glutamate receptor ionotropic, NMDA 2D	0	5	2	10
Glutamate receptor ionotropic, NMDA 3B	0	5	2	10
Carbonic anhydrase 4	0	0	0	1
Glutamate receptor ionotropic, NMDA 3A	0	5	2	10
Gamma-aminobutyric acid type B receptor subunit 2	0	2	2	4
Gamma-aminobutyric acid type B receptor subunit 2	0	3	0	3
Gamma-aminobutyric acid type B receptor subunit 1	0	2	2	4
Gamma-aminobutyric acid type B receptor subunit 1	0	2	0	2
Adenosine receptor A3	0	11	0	11
V-type proton ATPase subunit S1	0	1	0	1
Vacuolar proton pump subunit B	0	1	0	1
DNA polymerase beta	5	0	0	5
neuropeptide S receptor isoform A	8	0	0	8
Voltage-dependent L-type calcium channel subunit alpha-1D	0	3	0	4
Voltage-dependent L-type calcium channel subunit alpha-1S	0	3	0	4
Transient receptor potential cation channel subfamily A member 1	0	0	4	4
Rap guanine nucleotide exchange factor 4	4	0	0	4
Glutamate receptor ionotropic, NMDA 2D	0	2	1	3
Glutamate receptor ionotropic, NMDA 3B	0	2	1	3
Bile salt export pump	0	6	0	8
Fatty acid-binding protein, liver	0	4	1	5
Muscarinic acetylcholine receptor M1	0	3	2	5
Muscarinic acetylcholine receptor M3	0	3	2	5
Muscarinic acetylcholine receptor M4	0	3	2	5
Muscarinic acetylcholine receptor M5	0	3	2	5
Muscarinic acetylcholine receptor M2	0	3	2	5
Peroxisome proliferator-activated receptor alpha	0	0	2	2
Peroxisome proliferator-activated receptor delta	0	0	1	1
Peroxisome proliferator-activated receptor gamma	0	0	3	3
Peroxisome proliferator-activated receptor delta	0	0	1	1
Glutamate receptor ionotropic, NMDA 1	0	3	1	4
Peroxisome proliferator-activated receptor alpha	2	1	4	7
Glutamate receptor ionotropic, NMDA 2A	0	3	1	4
Glutamate receptor ionotropic, NMDA 2B	0	3	1	4
Glutamate receptor ionotropic, NMDA 2C	0	2	1	3
Glutamate receptor ionotropic, NMDA 3A	0	2	1	3
Chain A, Avidin	0	0	1	1
Chain A, Protein (streptavidin)	0	0	1	1
Chain B, Protein (streptavidin)	0	0	1	1
Chain A, Streptavidin	0	0	1	1
Chain D, Streptavidin	0	0	1	1
Chain A, Streptavidin	0	0	1	1
Chain D, Streptavidin	0	0	1	1
Chain A, Streptavidin	0	0	1	1
Chain D, Streptavidin	0	0	1	1
Chain A, Streptavidin Complex With Biotin	0	0	1	1
Chain D, Circularly Permuted Core-streptavidin E51/a46	0	0	1	1
Chain A, Core-streptavidin	0	0	1	1
Chain D, Core-streptavidin	0	0	1	1
Chain A, Core-streptavidin	0	0	1	1
Chain D, Core-streptavidin	0	0	1	1
Chain A, Core-streptavidin	0	0	1	1
Chain D, Core-streptavidin	0	0	1	1
Chain A, Core-streptavidin	0	0	1	1
Chain D, Core-streptavidin	0	0	1	1
Chain A, Avidin	0	0	1	1
Chain A, Streptavidin	0	0	1	1
Chain B, Streptavidin	0	0	1	1
Chain A, Streptavidin	0	0	1	1
Chain B, Streptavidin	0	0	1	1
green fluorescent protein, partial	0	1	0	1
insulin-degrading enzyme isoform 1	0	0	1	1
Streptavidin	0	0	1	1
Receptor-type tyrosine-protein phosphatase beta	0	0	0	1
Chain H, Proteasome component PUP1	0	1	0	1
Chain I, Proteasome component PUP3	0	1	0	1
Chain K, Proteasome component PRE2	0	1	0	1
Chain L, Proteasome component C5	0	1	0	1
Chain K, Proteasome component PRE2	0	1	0	1
Chain L, Proteasome component C5	0	1	0	1
Proteasome subunit beta type-11	0	1	0	1
PPM1D protein	10	0	0	10
caspase 7, apoptosis-related cysteine protease	15	0	0	15
caspase-3	15	0	0	15
26S proteasome non-ATPase regulatory subunit 11	0	1	0	1
26S proteasome non-ATPase regulatory subunit 12	0	1	0	1
26S proteasome non-ATPase regulatory subunit 14	0	1	0	1
Proteasome subunit alpha type-7	0	1	0	1
26S proteasome non-ATPase regulatory subunit 3	0	1	0	1
Carbonic anhydrase 12	0	6	0	9
Prothrombin	0	1	1	3
Chymotrypsinogen A	0	2	0	2
Carbonic anhydrase 3	0	4	0	6
Cathepsin B	0	6	0	6
Neutrophil elastase	0	6	0	6
Cathepsin G	0	2	0	2
Lysosomal protective protein	0	2	0	2
Chymotrypsinogen B	0	1	0	1
26S proteasome regulatory subunit 6A	0	1	0	1
Nuclear factor NF-kappa-B p105 subunit	0	3	0	3
Proteasome subunit beta type-1	0	1	0	2
Carbonic anhydrase 4	0	6	0	9
Carbonic anhydrase 6	0	4	0	7
Chymase	0	1	0	1
Proteasome subunit alpha type-1	0	1	0	1
Proteasome subunit alpha type-2	0	1	0	1
Proteasome subunit alpha type-3	0	1	0	1
Proteasome subunit alpha type-4	0	1	0	1
Proteasome subunit beta type-8	0	1	0	1
Proteasome subunit beta type-8	0	1	0	1
Proteasome subunit beta type-9	0	1	0	1
Proteasome subunit alpha type-5	0	1	0	1
Proteasome subunit beta type-4	0	1	0	1
Proteasome subunit beta type-6	0	1	0	1
Proteasome subunit beta type-5	0	4	0	5
Carbonic anhydrase 5A, mitochondrial	0	5	1	9
26S proteasome regulatory subunit 7	0	1	0	1
Lon protease homolog, mitochondrial	0	1	0	1
Proteasome subunit beta type-10	0	1	0	1
Carbonic anhydrase 7	0	5	0	8
26S proteasome regulatory subunit 6B	0	1	2	3
26S proteasome non-ATPase regulatory subunit 8	0	1	0	1
Proteasome subunit beta type-3	0	1	0	1
Proteasome subunit beta type-2	0	1	0	2
26S proteasome non-ATPase regulatory subunit 7	0	1	0	1
26S proteasome non-ATPase regulatory subunit 4	0	1	0	1
26S proteasome complex subunit SEM1	0	1	0	1
Proteasome subunit alpha type-6	0	1	1	2
26S proteasome regulatory subunit 4	0	1	0	1
26S proteasome regulatory subunit 8	0	1	0	1
26S proteasome regulatory subunit 10B	0	1	0	1
Beta-carbonic anhydrase 1	0	2	0	2
Nuclear factor NF-kappa-B p100 subunit	0	2	0	2
Transcription factor p65	0	2	0	2
26S proteasome non-ATPase regulatory subunit 2	0	1	0	1
26S proteasome non-ATPase regulatory subunit 6	0	1	0	1
Proteasomal ubiquitin receptor ADRM1	0	1	0	1
Carbonic anhydrase 9	0	7	1	11
ATP-dependent Clp protease proteolytic subunit	0	1	1	2
Carbonic anhydrase 13	0	4	0	4
NACHT, LRR and PYD domains-containing protein 3	0	1	0	1
Proteasome subunit alpha-type 8	0	1	0	1
Proteasome subunit beta type-7	0	1	0	1
26S proteasome non-ATPase regulatory subunit 1	0	1	0	1
Carbonic anhydrase 15	0	3	0	5
Carbonic anhydrase 14	0	4	0	7
26S proteasome non-ATPase regulatory subunit 13	0	1	0	1
Carbonic anhydrase 5B, mitochondrial	0	4	0	7
PAX8	0	0	0	1
NPC intracellular cholesterol transporter 1 precursor	10	0	0	10
major prion protein preproprotein Prp precursor	0	1	0	1
nuclear receptor subfamily 0 group B member 1	0	1	0	1
steroidogenic factor 1	0	1	0	1
ClpP	3	0	0	3
electroneutral potassium-chloride cotransporter KCC2	0	0	1	1
TSHR protein	1	0	0	1
LacZ protein (plasmid)	0	0	1	1
XBP1	0	2	0	2
serine-protein kinase ATM isoform a	3	0	0	3
hexokinase-4 isoform 1	4	0	0	4
type-1 angiotensin II receptor	0	1	0	1
parathyroid hormone/parathyroid hormone-related peptide receptor precursor	6	0	0	6
potassium voltage-gated channel subfamily H member 2 isoform d	24	0	0	24
glucokinase regulatory protein	4	0	0	4
mitogen-activated protein kinase 1	19	0	0	19
apelin receptor	0	2	0	2
DNA damage-inducible transcript 3 protein	0	2	0	2
Vpr	1	0	0	1
streptokinase A precursor	0	0	6	6
Rap guanine nucleotide exchange factor 3	7	0	0	7
Alpha-synuclein	6	3	1	10
HSP40, subfamily A [Plasmodium falciparum 3D7]	0	0	0	1
Acetylcholinesterase	0	7	0	7
Cytochrome P450 1A1	0	5	0	5
Cytochrome P450 2C11	0	2	0	2
5-hydroxytryptamine receptor 1A	0	2	4	6
Cytochrome P450 2D6	0	5	0	6
Cytochrome P450 2A6	0	2	0	2
Steroid 17-alpha-hydroxylase/17,20 lyase	0	1	0	1
Fatty acid-binding protein, liver	0	2	0	2
5-hydroxytryptamine receptor 2A	0	7	3	10
Cytochrome P450 2B6	0	2	0	2
Cytochrome P450 3A5	0	3	0	3
Cannabinoid receptor 1	0	7	1	10
D(1A) dopamine receptor	0	11	0	11
Cytochrome P450 3A7	0	1	0	1
Caspase-1	0	0	1	1
Cytochrome P450 2C19	0	7	0	8
Cannabinoid receptor 2	0	3	2	7
Cholinesterase	0	6	0	6
N-acylethanolamine-hydrolyzing acid amidase	0	1	0	1
Cytochrome P450 1B1	0	6	0	6
Heat sensitive channel TRPV3	0	1	1	2
Sigma intracellular receptor 2	0	3	0	3
Transient receptor potential cation channel subfamily V member 1	0	1	1	2
Transient receptor potential cation channel subfamily M member 8	0	1	0	1
Transient receptor potential cation channel subfamily V member 4	0	1	1	2
G-protein coupled receptor 55	0	1	2	3
Diacylglycerol lipase-alpha	0	1	0	1
Histamine H3 receptor	0	3	0	3
Solute carrier family 22 member 5	0	0	0	1
Solute carrier family 22 member 5	0	0	0	1
Solute carrier family 22 member 16	0	0	0	1
Solute carrier family 22 member 21	0	0	0	1
Solute carrier family 22 member 5	0	0	0	1
Chain A, Protein kinase CK2, alpha Subunit	0	1	0	1
Chain A, PROTEIN KINASE CK2, alpha SUBUNIT	0	1	0	1
Chain A, Protein Kinase Ck2, Alpha Subunit	0	1	0	1
Serine/threonine-protein kinase Sgk1	0	1	0	1
Ribosyldihydronicotinamide dehydrogenase [quinone]	0	6	4	10
Casein kinase II subunit alpha	0	1	0	1
Casein kinase II subunit beta	0	1	0	1
Cyclin-A1	0	1	0	1
Dual specificity mitogen-activated protein kinase kinase 1	0	1	2	3
Dual specificity tyrosine-phosphorylation-regulated kinase 1A	0	1	2	3
Ribosomal protein S6 kinase alpha-1	0	1	2	3
Casein kinase II subunit alpha 3	0	3	0	3
Single-stranded DNA cytosine deaminase	3	0	0	3
thyrotropin-releasing hormone receptor	6	0	0	6
Caspase-2	0	0	1	1
Dihydroxyacetone phosphate acyltransferase	0	0	0	1
30S ribosomal protein S6	0	2	0	2
30S ribosomal protein S7	0	2	0	2
50S ribosomal protein L15	0	2	0	2
50S ribosomal protein L10	0	2	0	2
50S ribosomal protein L11	0	2	0	2
50S ribosomal protein L7/L12	0	2	0	2
50S ribosomal protein L19	0	2	0	2
50S ribosomal protein L1	0	2	0	2
50S ribosomal protein L20	0	2	0	2
50S ribosomal protein L27	0	2	0	2
50S ribosomal protein L28	0	2	0	2
50S ribosomal protein L29	0	2	0	2
50S ribosomal protein L31	0	2	0	2
50S ribosomal protein L31 type B	0	2	0	2
50S ribosomal protein L32	0	2	0	2
50S ribosomal protein L33	0	2	0	2
50S ribosomal protein L34	0	2	0	2
50S ribosomal protein L35	0	2	0	2
50S ribosomal protein L36	0	2	0	2
30S ribosomal protein S10	0	2	0	2
30S ribosomal protein S11	0	2	0	2
30S ribosomal protein S12	0	2	0	2
30S ribosomal protein S13	0	2	0	2
30S ribosomal protein S16	0	2	0	2
30S ribosomal protein S18	0	2	0	2
30S ribosomal protein S19	0	2	0	2
30S ribosomal protein S20	0	2	0	2
30S ribosomal protein S2	0	2	0	2
30S ribosomal protein S3	0	2	0	2
30S ribosomal protein S4	0	2	0	2
30S ribosomal protein S5	0	2	0	2
30S ribosomal protein S8	0	2	0	2
30S ribosomal protein S9	0	2	0	2
50S ribosomal protein L13	0	2	0	2
50S ribosomal protein L14	0	2	0	2
50S ribosomal protein L16	0	2	0	2
50S ribosomal protein L23	0	2	0	2
30S ribosomal protein S15	0	2	0	2
50S ribosomal protein L17	0	2	0	2
50S ribosomal protein L21	0	2	0	2
50S ribosomal protein L30	0	2	0	2
50S ribosomal protein L6	0	2	0	2
30S ribosomal protein S14	0	2	0	2
30S ribosomal protein S17	0	2	0	2
30S ribosomal protein S1	0	2	0	2
50S ribosomal protein L18	0	2	0	2
50S ribosomal protein L2	0	2	0	2
50S ribosomal protein L3	0	2	0	2
50S ribosomal protein L24	0	2	0	2
50S ribosomal protein L4	0	2	0	2
50S ribosomal protein L22	0	2	0	2
50S ribosomal protein L5	0	2	0	2
30S ribosomal protein S21	0	2	0	2
50S ribosomal protein L25	0	2	0	2
50S ribosomal protein L36 2	0	2	0	2
Methionine--tRNA ligase, mitochondrial	0	0	1	1
glucose-6-phosphate dehydrogenase-6-phosphogluconolactonase	0	1	0	1
Spike glycoprotein	0	1	6	7
Replicase polyprotein 1ab	0	1	6	7
glucose-6-phosphate 1-dehydrogenase isoform b	0	1	0	1
Transmembrane protease serine 2	0	1	6	7
Dihydrofolate reductase	0	1	0	1
DNA ligase	0	1	0	1
Riboflavin-binding protein	0	1	2	3
Major prion protein	0	0	1	1
Histidine-rich protein PFHRP-II	0	1	0	2
Procathepsin L	0	5	6	11
Muscarinic acetylcholine receptor M2	0	11	0	12
Muscarinic acetylcholine receptor M4	0	13	0	14
Muscarinic acetylcholine receptor M5	0	13	0	14
Replicase polyprotein 1a	0	1	6	7
Replicase polyprotein 1ab	0	1	6	7
Replicase polyprotein 1ab	0	5	7	12
Spike glycoprotein	0	1	1	2
Replicase polyprotein 1ab	0	7	7	14
Muscarinic acetylcholine receptor M1	0	12	2	16
DNA ligase 1	0	1	0	1
Muscarinic acetylcholine receptor M3	0	14	0	15
Beta-secretase 1	0	2	0	2
Calcium-dependent protein kinase 1	0	0	1	1
MO15-related protein kinase Pfmrk	0	1	0	1
DNA ligase A	0	1	0	1
Potassium voltage-gated channel subfamily H member 2	0	21	0	21
Phosphoethanolamine N-methyltransferase	0	1	0	1
Sigma non-opioid intracellular receptor 1	0	13	0	13
Angiotensin-converting enzyme 2	0	1	6	7
Cysteine proteinase falcipain 2a	0	4	0	4
Cysteine proteinase falcipain 2a	0	1	0	1
Chain A, Acetylcholinesterase	0	0	1	1
Chain A, Acetylcholinesterase	0	0	1	1
Chain A, Acetylcholinesterase	0	0	1	1
Chain A, Acetylcholinesterase	0	0	1	1
Chain A, Acetylcholinesterase	0	0	1	1
Chain A, Acetylcholinesterase	0	0	1	1
Chain A, Acetylcholinesterase	0	0	1	1
Chain A, Putative Glycine Betaine-binding Abc Transporter Protein	0	0	1	1
Chain A, PUTATIVE GLYCINE BETAINE-BINDING ABC TRANSPORTER PROTEIN	0	0	1	1
Chain A, Glycine betaine/carnitine/choline-binding protein	0	0	1	1
Chain A, Glycine betaine/carnitine/choline-binding protein	0	0	1	1
Chain A, Glycine betaine/carnitine/choline-binding protein	0	0	1	1
Chain A, Glycine betaine/carnitine/choline-binding protein	0	0	1	1
Chain A, Choline-binding protein	0	0	1	1
Solute carrier family 22 member 1	0	1	0	2
Solute carrier family 22 member 2	0	2	0	4
Solute carrier family 22 member 1	0	7	0	8
Solute carrier family 22 member 2	0	1	0	1
Neuronal acetylcholine receptor subunit alpha-3	0	2	0	2
Neuronal acetylcholine receptor subunit alpha-2	0	1	0	1
Neuronal acetylcholine receptor subunit beta-3	0	1	0	1
Neuronal acetylcholine receptor subunit beta-4	0	2	0	2
Neuronal acetylcholine receptor subunit alpha-5	0	1	0	1
Acetylcholinesterase	0	8	0	8
Sodium- and chloride-dependent creatine transporter 1	0	1	0	1
Choline O-acetyltransferase	0	0	0	1
Neuronal acetylcholine receptor subunit alpha-6	0	2	0	2
Neuronal acetylcholine receptor subunit alpha-9	0	1	0	1
Neuronal acetylcholine receptor subunit alpha-7	0	2	0	2
Solute carrier family 22 member 1	0	3	0	4
High affinity choline transporter 1	0	1	0	1
Neuronal acetylcholine receptor subunit alpha-10	0	1	0	1
Solute carrier family 22 member 2	0	3	0	4
Sodium-dependent noradrenaline transporter	0	1	0	1
Aldo-keto reductase family 1 member B1	0	17	0	17
Tryptophan 5-hydroxylase 1	0	2	0	2
Angiotensin-converting enzyme	0	13	0	13
Aldo-keto reductase family 1 member B1	0	2	0	2
5-hydroxytryptamine receptor 1A	0	18	2	21
Aromatase	0	1	0	1
Sodium-dependent noradrenaline transporter	0	17	3	20
Sodium-dependent dopamine transporter	0	4	2	6
Sodium-dependent serotonin transporter	0	15	2	17
Histamine H1 receptor	0	11	1	12
5-hydroxytryptamine receptor 7	0	3	0	3
Sigma intracellular receptor 2	0	1	0	1
Sodium-dependent serotonin transporter	0	1	0	1
Sodium-dependent dopamine transporter	0	1	0	1
Nuclear receptor subfamily 3 group C member 3	0	11	0	11
Sigma non-opioid intracellular receptor 1	0	4	2	6
Transporter	0	5	0	5
N(G),N(G)-dimethylarginine dimethylaminohydrolase 1	0	1	0	1
General amino-acid permease GAP1	0	0	0	1
Beta-2 adrenergic receptor	0	2	1	3
Beta-1 adrenergic receptor	0	4	0	4
5-hydroxytryptamine receptor 1B	0	12	1	13
Delta-type opioid receptor	0	3	1	4
Beta-2 adrenergic receptor	0	0	1	3
Beta-2 adrenergic receptor	0	0	1	2
mitogen-activated protein kinase kinase kinase kinase 2 isoform 1	0	0	1	1
eyes absent homolog 2 isoform a	4	0	0	4
mitogen-activated protein kinase kinase kinase 3 isoform 1	0	0	1	1
Estrogen receptor	0	0	4	5
Cruzipain	0	4	0	4
C-terminal-binding protein 1	2	0	0	2
Estrogen receptor beta	0	0	4	5
Broad substrate specificity ATP-binding cassette transporter ABCG2	0	11	1	13
Gamma-aminobutyric acid receptor subunit pi	0	4	0	4
Gamma-aminobutyric acid receptor subunit delta	0	4	0	4
Gamma-aminobutyric acid receptor subunit alpha-1	0	3	0	4
Gamma-aminobutyric acid receptor subunit beta-1	0	3	0	4
Gamma-aminobutyric acid receptor subunit alpha-2	0	3	0	4
Gamma-aminobutyric acid receptor subunit alpha-3	0	3	0	4
Gamma-aminobutyric acid receptor subunit alpha-1	0	5	3	8
Gamma-aminobutyric acid receptor subunit beta-1	0	4	2	6
Gamma-aminobutyric acid receptor subunit gamma-2	0	5	3	8
Gamma-aminobutyric acid receptor subunit alpha-4	0	3	0	4
Gamma-aminobutyric acid receptor subunit gamma-2	0	3	0	4
Gamma-aminobutyric acid receptor subunit beta-3	0	5	3	8
Translocator protein	0	1	0	1
Translocator protein	0	1	0	1
Cholecystokinin receptor type A	1	3	0	4
Gastrin/cholecystokinin type B receptor	1	2	1	4
Gamma-aminobutyric acid receptor subunit alpha-5	0	4	3	7
Gamma-aminobutyric acid receptor subunit alpha-3	0	4	3	7
Gamma-aminobutyric acid receptor subunit alpha-2	0	4	2	6
Gamma-aminobutyric acid receptor subunit beta-2	0	4	2	6
Gamma-aminobutyric acid receptor subunit alpha-4	0	4	2	6
Gamma-aminobutyric acid receptor subunit epsilon	0	4	0	4
Gamma-aminobutyric acid receptor subunit alpha-6	0	4	2	6
Gamma-aminobutyric acid receptor subunit gamma-1	0	4	0	4
Gamma-aminobutyric acid receptor subunit gamma-3	0	4	0	4
Gamma-aminobutyric acid receptor subunit theta	0	4	0	4
GALC protein	7	0	0	7
Solute carrier family 22 member 3	0	1	0	1
Solute carrier family 22 member 3	0	1	0	1
Sex hormone-binding globulin	0	0	1	1
Corticosteroid-binding globulin	0	2	0	2
Mineralocorticoid receptor	0	2	2	4
Androgen receptor	0	6	0	6
C-8 sterol isomerase	0	2	0	2
Solute carrier organic anion transporter family member 1A1	0	1	0	3
3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase	0	3	1	4
Sodium- and chloride-dependent creatine transporter 1	0	1	0	1
Proton-coupled amino acid transporter 1	0	6	0	7
Chain A, Breast cancer type 1 susceptibility protein	3	0	0	3
Nrf2	1	0	0	1
alkaline phosphatase, intestinal	0	1	0	1
PINK1	2	0	0	2
toll-like receptor 9	0	1	0	1
alkaline phosphatase, tissue-nonspecific isozyme isoform 1 preproprotein	0	1	0	1
hemoglobin subunit beta	2	0	0	2
polyunsaturated fatty acid lipoxygenase ALOX12	3	0	0	3
perilipin-5	0	3	0	3
intestinal alkaline phosphatase precursor	0	1	0	1
perilipin-1	0	3	0	3
pyruvate kinase PKM isoform a	2	0	0	2
nuclear factor NF-kappa-B p105 subunit isoform 1	4	0	1	5
histone-lysine N-methyltransferase 2A isoform 2 precursor	6	0	0	6
1-acylglycerol-3-phosphate O-acyltransferase ABHD5 isoform a	0	3	0	3
alkaline phosphatase, germ cell type preproprotein	0	1	0	1
hypothetical protein SA1422	0	1	0	1
Prostaglandin E synthase	0	1	0	1
Lysine-specific histone demethylase 1A	0	2	0	2
D-amino-acid oxidase	0	1	0	1
Phospholipase A2	0	1	1	2
Sarcoplasmic/endoplasmic reticulum calcium ATPase 1	0	3	0	3
Neuronal proto-oncogene tyrosine-protein kinase Src	0	1	0	1
Prostaglandin G/H synthase 1	0	3	1	4
Cholinesterase	0	3	0	3
Heme oxygenase 1	0	1	0	1
Glutathione S-transferase P	0	2	0	2
Polyunsaturated fatty acid 5-lipoxygenase	0	7	0	7
Microtubule-associated protein tau	0	1	0	2
Sarcoplasmic/endoplasmic reticulum calcium ATPase 2	0	1	0	1
Aminopeptidase N	0	1	0	1
Aminopeptidase N	0	1	0	1
Sarcoplasmic/endoplasmic reticulum calcium ATPase 2	0	2	0	2
Glycogen synthase kinase-3 beta	0	2	0	2
Amine oxidase [flavin-containing] A	0	10	0	10
Heme oxygenase 2	0	1	0	1
Amine oxidase [flavin-containing] B	0	10	0	10
17-beta-hydroxysteroid dehydrogenase type 2	0	1	0	1
Caspase-7	4	0	0	4
Lactoylglutathione lyase	0	2	0	2
Histone acetyltransferase p300	0	1	0	1
Serine/threonine-protein kinase PAK 1	0	2	0	2
5-hydroxytryptamine receptor 4	0	0	1	1
Sodium/bile acid cotransporter	0	0	1	1
Nuclear factor erythroid 2-related factor 2	0	0	2	4
Thioredoxin reductase 1, cytoplasmic	0	1	0	1
Thioredoxin reductase 3	0	1	0	1
Sortase A	0	1	0	1
CREB-binding protein	0	1	0	1
Sarcoplasmic/endoplasmic reticulum calcium ATPase 3	0	2	0	2
Cysteine protease	0	3	0	3
NACHT, LRR and PYD domains-containing protein 3	0	1	0	1
Thioredoxin reductase 2, mitochondrial	0	1	0	1
CDGSH iron-sulfur domain-containing protein 1	0	4	0	4
Lymphocyte antigen 96	0	0	1	1
Beta lactamase (plasmid)	0	1	0	1
Phosphodiesterase	0	1	0	1
Multidrug resistance-associated protein 5	0	0	0	1
P53	4	0	0	4
RPL19A	0	0	1	1
transactivating tegument protein VP16 [Human herpesvirus 1]	0	2	0	2
COUP transcription factor 2 isoform a	0	1	0	1
Glucose transporter	0	1	0	1
Hexose transporter 1	0	1	0	1
Solute carrier family 2, facilitated glucose transporter member 1	0	1	0	1
Eukaryotic initiation factor 4A-I	0	1	0	1
Peptidyl-prolyl cis-trans isomerase FKBP1A	0	6	2	8
Peptidyl-prolyl cis-trans isomerase FKBP3	0	1	0	1
Peptidyl-prolyl cis-trans isomerase FKBP4	0	1	0	1
Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1	0	1	0	1
Hypoxia-inducible factor 1-alpha	0	1	1	2
Endothelial PAS domain-containing protein 1	0	1	0	1
Peptidyl-prolyl cis-trans isomerase FKBP14	0	1	0	1
Peptidyl-prolyl cis-trans isomerase NIMA-interacting 4	0	1	0	1
Histone-lysine N-methyltransferase EHMT2	0	1	0	1
Glutaminyl-peptide cyclotransferase	0	1	0	1
Histone-lysine N-methyltransferase EHMT1	0	1	0	1
Alpha-tocopherol transfer protein	0	0	1	1
NADH-ubiquinone oxidoreductase chain 4	0	0	0	1
72 kDa type IV collagenase	0	2	0	2
DNA topoisomerase 2-alpha	0	1	3	10
Carbonyl reductase [NADPH] 1	0	0	0	1
Glutamate receptor 1	1	3	2	6
Glutamate receptor 3	1	3	2	6
Glutamate receptor 4	1	3	2	6
Platelet-activating factor receptor	1	0	0	2
Multidrug resistance-associated protein 1	0	4	1	7
Reverse transcriptase/RNaseH	0	1	0	1
Lysine-specific demethylase 4A	0	1	0	1
Deoxyhypusine hydroxylase	0	1	0	1
Thymidine kinase, cytosolic	0	3	0	6
Deoxycytidine kinase	0	0	2	3
AAA family ATPase	0	0	0	1
Sterol O-acyltransferase 1	0	2	0	2
5-hydroxytryptamine receptor 2C	0	5	1	6
Phenylethanolamine N-methyltransferase	0	1	0	1
5-hydroxytryptamine receptor 1D	0	0	1	1
5-hydroxytryptamine receptor 1F	0	0	1	1
5-hydroxytryptamine receptor 2B	0	5	1	6
5-hydroxytryptamine receptor 6	0	0	1	1
5-hydroxytryptamine receptor 7	0	1	1	2
5-hydroxytryptamine receptor 5A	0	0	1	1
5-hydroxytryptamine receptor 5B	0	0	1	1
5-hydroxytryptamine receptor 3A	0	0	1	1
Amine oxidase [flavin-containing] B	0	1	0	1
5-hydroxytryptamine receptor 4	0	0	1	1
Trace amine-associated receptor 1	0	0	1	1
Trace amine-associated receptor 1	0	0	1	1
Trace amine-associated receptor 1	0	0	1	1
Trace amine-associated receptor 1	0	0	1	1
5-hydroxytryptamine receptor 3B	0	0	1	1
Transient receptor potential cation channel subfamily A member 1	0	1	1	3
Glycine receptor subunit alpha-1	0	0	3	3
D(3) dopamine receptor	0	15	1	16
Cannabinoid receptor 1	0	2	0	2
Cannabinoid receptor 2	0	1	2	3
N-arachidonyl glycine receptor	0	0	1	1
Lysophosphatidylserine lipase ABHD12	0	1	0	1
Monoglyceride lipase	0	1	0	1
Monoacylglycerol lipase ABHD6	0	1	0	1
Cannabinoid receptor 2	0	2	0	2
Calpain-9	0	1	0	1
Papain	0	3	0	3
Calpain-1 catalytic subunit	0	1	0	1
Pro-cathepsin H	0	3	0	3
Fatty acid synthase	0	1	0	1
Cathepsin S	0	1	0	1
Calpain-1 catalytic subunit	0	2	0	2
Dipeptidyl peptidase 1	0	1	0	1
Liver carboxylesterase	0	1	0	1
Cysteine protease falcipain-3	0	2	0	2
Cysteine protease falcipain-3	0	1	0	1
Genome polyprotein	0	3	1	4
chaperonin-containing TCP-1 beta subunit homolog	2	0	0	2
hypothetical protein, conserved	2	0	0	2
relaxin receptor 1 isoform 1	1	0	0	1
Flavin reductase (NADPH)	0	0	2	2
large T antigen	0	3	1	4
Voltage-dependent T-type calcium channel subunit alpha-1I	0	2	1	3
LMP1 [Human herpesvirus 4]	0	0	0	1
nuclear receptor coactivator 1 isoform 1 [Homo sapiens]	0	1	0	1
nuclear receptor coactivator 3 isoform a	0	1	0	1
Regulatory protein E2	0	0	1	1
ATP-dependent translocase ABCB1	0	3	0	3
DNA topoisomerase 1	0	1	0	2
Polyunsaturated fatty acid lipoxygenase ALOX15	0	5	0	5
DNA topoisomerase 2	0	0	0	1
ATP-dependent translocase ABCB1	0	3	0	4
UDP-glucuronosyltransferase 1A1	0	1	0	3
Serum paraoxonase/arylesterase 1	0	1	0	1
Caspase-3	0	1	0	1
DNA topoisomerase 2-alpha	0	0	0	1
DNA topoisomerase 2-beta	0	1	3	10
Tubulin beta-2B chain	0	2	0	2
Integrase	0	2	0	2
Similar to alpha-tubulin isoform 1	0	2	0	2
Similar to alpha-tubulin isoform 1	0	2	0	2
Fatty acid-binding protein, liver	0	1	0	1
Beta-3 adrenergic receptor	0	4	0	4
Peroxisome proliferator-activated receptor alpha	0	0	1	1
BRCA1	3	0	0	3
Glycoprotein hormones alpha chain	1	0	0	1
Retinol-binding protein 4	0	0	2	2
Prosaposin	0	0	1	1
Retinoic acid receptor gamma	0	1	0	1
Alpha-1A adrenergic receptor	0	1	0	1
Retinoic acid receptor RXR-alpha	0	1	0	1
Retinoic acid receptor RXR-beta	0	1	0	1
Indoleamine 2,3-dioxygenase 1	0	2	0	2
Retinoic acid receptor RXR-gamma	0	1	0	1
Indoleamine 2,3-dioxygenase 2	0	2	0	2
D(2) dopamine receptor	0	11	0	11
D(4) dopamine receptor	0	8	0	8
Delta-type opioid receptor	0	5	0	5
Mu-type opioid receptor	0	5	2	7
Kappa-type opioid receptor	0	1	0	1
Mu-type opioid receptor	0	1	0	1
Sigma non-opioid intracellular receptor 1	0	4	0	4
Sphingosine 1-phosphate receptor 1	0	0	1	1
RCG53912, isoform CRA_a	0	0	0	1
Sphingosine kinase 1	0	0	0	1
Sphingosine kinase 2	0	1	0	2
Sphingosine kinase 1	0	1	0	2
Voltage-dependent T-type calcium channel subunit alpha-1G	0	1	1	2
Voltage-dependent T-type calcium channel subunit alpha-1H	0	1	1	2
Sodium channel protein type 1 subunit alpha	0	2	0	2
Sodium channel protein type 2 subunit alpha	0	3	0	3
Sodium channel protein type 3 subunit alpha	0	2	0	2
Cytochrome P450 2J2	0	8	0	8
Voltage-dependent L-type calcium channel subunit beta-1	0	1	0	1
Voltage-dependent calcium channel subunit alpha-2/delta-1	0	1	0	1
D(2) dopamine receptor	0	9	0	9
Voltage-dependent N-type calcium channel subunit alpha-1B	0	2	0	2
Voltage-dependent N-type calcium channel subunit alpha-1B	0	1	0	1
Prostaglandin D2 receptor 2	0	1	0	1
atrial natriuretic peptide receptor 1 precursor	4	0	0	4
Potassium voltage-gated channel subfamily KQT member 3	0	0	1	2
Potassium voltage-gated channel subfamily KQT member 2	0	0	1	2
Serine hydroxymethyltransferase, mitochondrial	0	1	0	1
Potassium voltage-gated channel subfamily KQT member 4	0	0	0	1
Potassium voltage-gated channel subfamily KQT member 5	0	0	0	1
phosphoglycerate kinase	3	0	0	3
alternatively spliced Trp4	0	0	1	1
replicative DNA helicase	0	0	0	1
recombinase A	0	0	1	1
Nociceptin receptor	0	1	0	1
Gamma-aminobutyric acid	0	0	1	1
Gamma-aminobutyric acid receptor subunit rho-3	0	0	1	1
Hsf1 protein	0	0	2	3
Gamma-aminobutyric acid receptor subunit alpha-6	0	0	1	1
Gamma-aminobutyric acid receptor subunit gamma-2	0	0	1	1
Gamma-aminobutyric acid receptor subunit delta	0	0	1	1
Sodium- and chloride-dependent GABA transporter 1	0	2	0	2
Gamma-aminobutyric acid receptor subunit rho-1	0	0	2	2
Gamma-aminobutyric acid receptor subunit alpha-2	0	0	1	1
Gamma-aminobutyric acid receptor subunit alpha-3	0	0	1	1
Gamma-aminobutyric acid receptor subunit gamma-3	0	0	1	1
Gamma-aminobutyric acid receptor subunit rho-2	0	0	1	1
Sodium- and chloride-dependent GABA transporter 1	0	1	0	1
Sodium- and chloride-dependent taurine transporter	0	2	0	2
Sodium- and chloride-dependent GABA transporter 2	0	2	0	2
Sodium- and chloride-dependent GABA transporter 3	0	2	0	2
Sodium- and chloride-dependent GABA transporter 1	0	1	0	1
Sodium- and chloride-dependent GABA transporter 2	0	1	0	1
Sodium- and chloride-dependent GABA transporter 3	0	1	0	1
Sodium- and chloride-dependent betaine transporter	0	2	0	2
Sodium- and chloride-dependent betaine transporter	0	1	0	1
Sodium- and chloride-dependent GABA transporter 3	0	1	0	1
Gamma-aminobutyric acid receptor subunit beta-1	0	0	1	1
Gamma-aminobutyric acid receptor subunit alpha-1	0	0	1	1
Gamma-aminobutyric acid receptor subunit beta-3	0	0	1	1
4-aminobutyrate aminotransferase, mitochondrial	0	0	0	1
4-aminobutyrate aminotransferase, mitochondrial	0	0	0	1
Sterol O-acyltransferase 1	0	0	1	1
Gamma-aminobutyric acid receptor subunit alpha-5	0	0	1	1
Gamma-aminobutyric acid receptor subunit pi	0	0	1	1
Gamma-aminobutyric acid receptor subunit alpha-4	0	0	1	1
Platelet glycoprotein VI	0	0	1	1
Gamma-aminobutyric acid receptor subunit theta	0	0	1	1
Sodium- and chloride-dependent GABA transporter 2	0	1	0	1
Gamma-aminobutyric acid receptor subunit gamma-1	0	0	1	1
Cytochrome P450 2C8	0	2	0	2
Guanylate cyclase soluble subunit alpha-1	0	0	1	1
Guanylate cyclase soluble subunit beta-1	0	0	1	1
Chain A, GLUTAMATE RECEPTOR SUBUNIT 2	0	1	0	1
Chain A, Glutamate Receptor Subunit 2	0	1	0	1
Chain B, Glutamate Receptor Subunit 2	0	1	0	1
Chain A, Slr1257 protein	0	0	1	1
Chain A, Glucosamine--fructose-6-phosphate aminotransferase [isomerizing]	0	1	0	1
beta-2 adrenergic receptor	2	0	0	2
Metabotropic glutamate receptor 8	0	2	0	2
Glutathione reductase, mitochondrial	0	7	0	8
Bifunctional aspartokinase/homoserine dehydrogenase 1	0	1	0	1
ATP-citrate synthase	0	1	0	1
Glutamate receptor ionotropic, kainate 1	0	2	1	3
Metabotropic glutamate receptor 1	0	2	1	3
Metabotropic glutamate receptor 2	0	0	1	1
Metabotropic glutamate receptor 3	0	0	1	1
Metabotropic glutamate receptor 4	0	1	1	2
Metabotropic glutamate receptor 5	0	0	1	1
Metabotropic glutamate receptor 6	0	0	1	1
Metabotropic glutamate receptor 7	0	0	1	1
Glutamate receptor ionotropic, kainate 1	0	1	1	2
Metabotropic glutamate receptor 5	0	1	1	3
Glutamate receptor ionotropic, kainate 2	0	2	1	3
Glutamate receptor 1	0	3	1	4
Glutamate receptor 2	0	2	1	3
Glutamate receptor 3	0	1	1	2
Glutamate receptor ionotropic, kainate 3	0	2	0	2
Metabotropic glutamate receptor 8	0	0	1	1
Glutamate receptor 4	0	2	1	3
Excitatory amino acid transporter 3	0	0	0	1
Glutamate racemase	0	0	0	1
Metabotropic glutamate receptor 8	0	1	1	2
Fatty-acid amide hydrolase 1	0	4	0	4
Glutamate receptor ionotropic, kainate 4	0	2	0	2
Glutamate carboxypeptidase 2	0	1	0	1
Glutamate receptor ionotropic, kainate 2	0	1	1	2
Glutamate receptor ionotropic, kainate 3	0	1	0	1
Metabotropic glutamate receptor 7	0	1	1	3
Metabotropic glutamate receptor 3	0	1	1	3
Metabotropic glutamate receptor 4	0	1	1	3
Glutamate receptor ionotropic, kainate 5	0	1	0	1
Glutamate receptor ionotropic, kainate 5	0	2	0	2
Glutamate racemase	0	0	0	1
Prolyl 4-hydroxylase	0	2	0	2
Alpha-ketoglutarate-dependent dioxygenase FTO	0	2	0	2
Chain A, Glutamine Binding Protein	0	0	1	1
Asc-type amino acid transporter 1	0	1	0	1
Chain B, EUKARYOTIC TRANSLATION INITIATION FACTOR 4E	0	0	1	1
Purine nucleoside phosphorylase	0	2	0	2
Ricin	0	1	0	1
2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase	0	0	1	1
Purine nucleoside phosphorylase	0	0	1	2
Guanine deaminase	0	1	0	2
Cyclic GMP-AMP synthase	0	1	0	1
Toll-like receptor 9	0	1	0	1
Toll-like receptor 7	0	1	0	1
Aldo-keto reductase family 1 member B1	0	2	0	2
Genome polyprotein	0	1	0	1
Testosterone 17-beta-dehydrogenase 3	0	1	0	1
Small conductance calcium-activated potassium channel protein 3	0	1	0	1
Sorbitol dehydrogenase	0	1	0	1
Induced myeloid leukemia cell differentiation protein Mcl-1	0	2	0	2
Oleandomycin glycosyltransferase	0	0	0	1
Chain B, Pulmonary surfactant-associated protein D	0	1	0	1
Chain A, Pulmonary surfactant-associated protein D	0	1	0	1
Sodium/myo-inositol cotransporter 2	0	1	0	1
Dihydrofolate reductase	0	2	0	2
Potassium voltage-gated channel subfamily E member 1	0	1	0	1
Sodium channel protein type 4 subunit alpha	0	2	0	3
Potassium voltage-gated channel subfamily KQT member 1	0	1	0	1
Sodium channel protein type 5 subunit alpha	0	5	0	5
Sodium channel protein type 9 subunit alpha	0	2	0	2
Sodium channel protein type 2 subunit alpha	0	3	0	3
Sodium channel protein type 3 subunit alpha	0	3	0	3
Sodium channel protein type 10 subunit alpha	0	2	0	2
Chain A, AMINOPEPTIDASE	0	1	0	1
Chain A, AMINOPEPTIDASE	0	1	0	1
Chain A, Leucine Aminopeptidase	0	1	0	1
Intestinal-type alkaline phosphatase	0	2	0	2
Large neutral amino acids transporter small subunit 1	0	4	0	4
Phospholipase A-2-activating protein	0	2	0	2
Cathepsin B	0	1	0	1
Prothrombin	0	1	0	1
Plasminogen	0	1	0	1
Cationic trypsin	0	2	0	2
Plasma kallikrein	0	1	0	3
Serine protease hepsin	0	1	0	1
Plasminogen	0	1	0	1
Trypsin-1	0	1	0	1
Trypsin-2	0	1	0	1
Cathepsin B	0	1	0	1
Trypsin-3	0	1	0	1
Cathepsin K	0	1	0	1
Hepatocyte growth factor activator	0	1	0	1
Transmembrane protease serine 6	0	1	0	1
Cysteine protease	0	2	0	2
Suppressor of tumorigenicity 14 protein	0	1	0	1
Synaptic vesicle glycoprotein 2A	0	2	0	2
integrase, partial	0	2	0	2
lens epithelium-derived growth factor p75	0	2	0	2
pyruvate kinase	2	0	0	2
Epidermal growth factor receptor	0	4	2	6
Adenosine receptor A1	0	1	0	2
Adenosine receptor A2a	0	3	0	4
Carbonic anhydrase	0	0	0	2
Solute carrier family 15 member 1	0	1	0	1
Carbonic anhydrase	0	1	0	3
SLC16A10 protein	0	0	0	2
Carbonic anhydrase	0	1	0	3
Carbonic anhydrase	0	0	0	2
Carbonic anhydrase	0	1	0	3
Carbonic anhydrase	0	1	0	3
Monocarboxylate transporter 10	0	0	0	2
Carbonic anhydrase 13	0	0	0	3
Voltage-dependent L-type calcium channel subunit alpha-1F	0	7	0	7
DNA gyrase subunit A	0	1	0	1
DNA gyrase subunit B	0	1	0	1
Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial	0	1	0	1
Voltage-dependent L-type calcium channel subunit alpha-1D	0	7	0	7
Voltage-dependent L-type calcium channel subunit alpha-1S	0	7	0	7
Dual specificity tyrosine-phosphorylation-regulated kinase 1A	0	1	0	1
Renin	0	1	0	1
inositol monophosphatase 1	1	0	0	1
5-hydroxytryptamine receptor 1A	0	2	0	2
Type-1 angiotensin II receptor	0	1	0	1
Chain A, Transthyretin	0	0	1	1
Chain A, Transthyretin	0	0	1	1
Chain A, Transthyretin	0	0	1	1
Chain A, Transthyretin	0	0	1	1
Chain B, Transthyretin	0	0	1	1
Chain A, Transthyretin	0	0	1	1
Chain B, Transthyretin	0	0	1	1
Chain A, Casein kinase II subunit alpha	0	1	0	1
Chain A, Casein kinase II subunit alpha	0	1	0	1
Chain A, Casein Kinase Ii Subunit Alpha	0	1	0	1
histidine kinase	0	1	0	1
cystic fibrosis transmembrane conductance regulator ATP-binding cassette sub-family C member 7	0	0	0	1
Neuraminidase	0	2	0	2
galactokinase	1	0	0	1
glycogen synthase kinase-3 beta isoform 1	0	0	1	1
POsterior Segregation	0	0	2	2
Aldo-keto reductase family 1 member B10	0	1	0	1
G2/mitotic-specific cyclin-B2	0	1	0	1
Poly [ADP-ribose] polymerase tankyrase-1	0	1	0	1
Interstitial collagenase	0	1	0	1
Glucocorticoid receptor	0	6	2	14
Chemotaxis protein CheA	0	1	0	1
Tyrosine-protein kinase Yes	0	1	2	3
Seed linoleate 13S-lipoxygenase-1	0	2	0	4
Stromelysin-1	0	3	0	3
Poly [ADP-ribose] polymerase 1	0	1	0	1
Enoyl-[acyl-carrier-protein] reductase [NADH] FabI	0	1	0	1
Alpha-amylase 1A	0	1	0	1
Androgen receptor	0	2	0	3
Sialidase	0	1	0	1
Fatty acid synthase	0	1	0	1
G2/mitotic-specific cyclin-B1	0	1	0	1
Matrix metalloproteinase-9	0	2	0	2
Urease subunit alpha	0	2	0	2
G2/mitotic-specific cyclin-B	0	1	0	1
Polyunsaturated fatty acid lipoxygenase ALOX15	0	1	0	1
Dipeptidyl peptidase 4	0	2	0	2
Cytosol aminopeptidase	0	1	0	1
ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1	0	2	0	2
Substance-P receptor	0	2	0	2
Receptor-type tyrosine-protein kinase FLT3	0	2	2	4
Macrophage metalloelastase	0	1	0	1
Homeobox protein Nkx-2.5	0	1	0	1
Tyrosine-protein kinase SYK	0	1	3	4
Collagenase 3	0	2	0	2
1-deoxy-D-xylulose 5-phosphate reductoisomerase	0	1	0	1
Fatty acid synthase	0	2	0	2
Glycogen synthase kinase-3 alpha	0	1	2	3
Death-associated protein kinase 1	0	1	0	1
Mitogen-activated protein kinase 10	0	1	2	3
Urease subunit beta	0	2	0	2
Cyclin-dependent kinase 6	0	1	2	3
Cyclin-dependent-like kinase 5	0	1	2	3
Cyclin homolog	0	1	0	1
Transcription factor GATA-4	0	1	0	1
Cyclin-dependent kinase 5 activator 1	0	1	0	1
Carbonic anhydrase 3	0	2	0	2
Substance-K receptor	0	1	0	1
Protein polybromo-1	0	0	1	1
Inositol polyphosphate multikinase	0	1	0	1
Histone-lysine N-methyltransferase SETD7	0	1	0	1
G2/mitotic-specific cyclin-B3	0	1	0	1
Enoyl-acyl-carrier protein reductase	0	2	0	2
3-oxoacyl-acyl-carrier protein reductase	0	2	0	2
Beta-hydroxyacyl-ACP dehydratase precursor (Fatty acid synthesis protein)	0	2	0	2
Aurora kinase B	0	2	2	4
MAP kinase-interacting serine/threonine-protein kinase 1	0	1	0	1
Cyclin-dependent kinase 1	0	1	0	1
Poly [ADP-ribose] polymerase tankyrase-2	0	1	0	1
MAP kinase-interacting serine/threonine-protein kinase 2	0	1	0	1
G-protein coupled receptor 35	0	1	1	2
NADPH oxidase 4	0	1	0	1
Dipeptidyl peptidase 3	0	1	0	1
Inositol hexakisphosphate kinase 2	0	1	0	1
Short transient receptor potential channel 5	0	1	0	1
DNA topoisomerase 1	0	1	0	1
Zinc finger protein mex-5	0	0	2	2
Sialidase-2	0	2	0	2
M1-family alanyl aminopeptidase	0	1	0	1
Chain A, Ribulose-1,5 bisphosphate carboxylase/oxygenase large subunit N-methyltransferase, chloroplast	0	1	0	1
Chain A, Ribulose-1,5 bisphosphate carboxylase/oxygenase large subunit N-methyltransferase, chloroplast	0	1	0	1
Methyl-accepting chemotaxis protein NahY	0	0	2	2
Alpha-mannosidase 2C1	0	1	0	1
Fucose-binding lectin PA-IIL	0	1	0	1
CD209 antigen	0	1	0	1
Glycine receptor subunit alpha-1	0	6	0	6
Glycine receptor subunit beta	0	6	0	6
Glycine receptor subunit alpha-2	0	6	0	6
Glycine receptor subunit alpha-3	0	6	0	6
Cytochrome P450 1A2	0	1	0	1
Myeloperoxidase	0	2	0	2
Acetylcholinesterase	0	1	0	1
Nociceptin receptor	0	1	0	1
Melatonin receptor type 1A	0	2	1	3
Melatonin receptor type 1C	0	0	1	1
Melatonin receptor type 1A	0	1	1	2
Melatonin receptor type 1B	0	2	1	3
Melatonin receptor type 1C	0	1	1	2
Melatonin receptor type 1B	0	1	1	2
Palmitoleoyl-protein carboxylesterase NOTUM	0	1	0	1
Carboxylic ester hydrolase	0	1	0	1
Chain A, Methionyl-tRNA synthetase	0	0	1	1
Chain A, Methionyl-tRNA synthetase	0	0	1	1
Chain A, Aminopeptidase	0	1	0	1
Chain A, Methionine aminopeptidase	0	1	0	1
S-ribosylhomocysteine lyase	0	1	0	1
Adenylate cyclase type 5	0	0	0	1
S-adenosylmethionine synthase isoform type-1	0	0	0	1
S-adenosylmethionine synthase isoform type-2	0	0	0	1
Gag-Pol polyprotein	0	1	0	1
Serine racemase	0	1	0	1
Albumin	0	1	2	3
Matrilysin	0	1	0	1
Multidrug transporter MdfA	0	1	0	1
Protein-arginine deiminase type-4	0	2	0	2
Chain A, Inosine-5'-Monophosphate Dehydrogenase 2	0	1	0	1
UDP-glucuronosyltransferase 1A9	0	0	0	3
Inosine-5'-monophosphate dehydrogenase 2	0	2	2	4
Inosine-5'-monophosphate dehydrogenase 1	0	2	0	2
Inosine-5'-monophosphate dehydrogenase	0	1	0	2
UDP-glucuronosyltransferase 1A7	0	0	0	1
UDP-glucuronosyltransferase 1A10	0	0	0	1
UDP-glucuronosyltransferase 1A8	0	0	0	2
Solute carrier family 22 member 20	0	1	0	1
Solute carrier family 22 member 6	0	1	0	1
Sialidase-4	0	1	0	1
Sialidase-1	0	1	0	1
Sialidase-3	0	1	0	1
Chain B, Exotoxin A	0	0	1	1
Chain B, Exotoxin A	0	0	1	1
Chain B, Exotoxin A	0	0	1	1
atrial natriuretic peptide receptor 2 precursor	4	0	0	4
Equilibrative nucleoside transporter 1	0	1	0	1
B2 bradykinin receptor	0	1	0	1
Quinolone resistance protein NorA	0	1	0	1
Adenosine receptor A3	0	1	0	1
Malate dehydrogenase, cytoplasmic	0	1	0	1
Phospholipase A2, membrane associated	0	0	0	1
Potassium voltage-gated channel subfamily A member 5	0	1	0	1
3-oxo-5-alpha-steroid 4-dehydrogenase 1	0	1	0	1
Thromboxane-A synthase	0	2	0	2
3-oxo-5-alpha-steroid 4-dehydrogenase 2	0	1	0	1
Sodium channel protein type 1 subunit alpha	0	2	0	2
C-C chemokine receptor type 2	0	2	0	2
Sodium channel protein type 7 subunit alpha	0	1	0	1
Voltage-dependent L-type calcium channel subunit alpha-1C	0	1	0	1
Voltage-dependent L-type calcium channel subunit alpha-1S	0	1	0	1
Potassium voltage-gated channel subfamily A member 1	0	1	0	1
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C	0	2	0	2
Leukotriene B4 receptor 1	0	0	0	1
Myosin light chain kinase, smooth muscle	0	1	2	3
Voltage-dependent L-type calcium channel subunit alpha-1D	0	1	0	1
Voltage-dependent L-type calcium channel subunit alpha-1F	0	1	0	1
Leukotriene B4 receptor 2	0	0	0	1
Sodium channel protein type 11 subunit alpha	0	1	0	1
Sodium channel protein type 8 subunit alpha	0	1	0	1
Voltage-dependent L-type calcium channel subunit beta-4	0	1	0	1
Voltage-dependent P/Q-type calcium channel subunit alpha-1A	0	1	0	1
Voltage-dependent calcium channel gamma-3 subunit	0	1	0	1
Voltage-dependent L-type calcium channel subunit beta-3	0	1	0	1
Voltage-dependent calcium channel subunit alpha-2/delta-1	0	1	0	1
Voltage-dependent calcium channel gamma-7 subunit	0	1	0	1
Voltage-dependent L-type calcium channel subunit beta-1	0	1	0	1
Voltage-dependent calcium channel gamma-1 subunit	0	1	0	1
Voltage-dependent L-type calcium channel subunit beta-2	0	1	0	1
cAMP-specific 3',5'-cyclic phosphodiesterase 4D	0	1	0	1
Voltage-dependent R-type calcium channel subunit alpha-1E	0	1	0	1
Voltage-dependent calcium channel subunit alpha-2/delta-4	0	1	0	1
Voltage-dependent calcium channel subunit alpha-2/delta-3	0	1	0	1
Voltage-dependent calcium channel gamma-8 subunit	0	1	0	1
Bile acid receptor	0	1	1	2
Voltage-dependent calcium channel gamma-6 subunit	0	1	0	1
Voltage-dependent calcium channel subunit alpha-2/delta-2	0	1	0	1
Voltage-dependent calcium channel gamma-4 subunit	0	1	0	1
Voltage-dependent calcium channel gamma-5 subunit	0	1	0	1
Voltage-dependent calcium channel gamma-2 subunit	0	1	0	1
5-hydroxytryptamine receptor 3E	0	1	0	1
FAD-linked sulfhydryl oxidase ALR	0	0	0	2
5-hydroxytryptamine receptor 3B	0	1	0	1
Glucose-6-phosphate 1-dehydrogenase	0	2	0	2
D	0	3	0	3
D(3) dopamine receptor	0	3	0	3
UDP-glucuronosyltransferase 1A4	0	0	0	3
D(4) dopamine receptor	0	2	0	2
Histamine H1 receptor	0	2	1	3
5-hydroxytryptamine receptor 7	0	3	0	3
5-hydroxytryptamine receptor 3A	0	1	0	1
3-hydroxy-3-methylglutaryl-coenzyme A reductase	0	2	0	2
Transporter	0	2	0	2
5-hydroxytryptamine receptor 3D	0	1	0	1
5-hydroxytryptamine receptor 3C	0	1	0	1
Solute carrier family 2, facilitated glucose transporter member 9	0	2	2	4
Chain A, Fatty acid-binding protein, adipocyte	0	1	0	1
Toll-like receptor 2	0	1	0	1
Olfactory receptor 51E2	0	0	2	2
Chain A, CATHEPSIN D	0	1	0	1
Chain B, CATHEPSIN D	0	1	0	1
Chain A, PLASMEPSIN II	0	1	0	1
Chain E, ENDOTHIAPEPSIN	0	1	0	1
Chain E, RHIZOPUSPEPSIN	0	1	0	1
Chain E, ENDOTHIAPEPSIN	0	1	0	1
Chain E, ENDOTHIAPEPSIN	0	1	0	1
Chain E, RHIZOPUSPEPSIN	0	1	0	1
Chain E, RHIZOPUSPEPSIN	0	1	0	1
Pepsin A	0	2	0	2
Renin	0	2	0	2
Cathepsin D	0	3	0	4
Candidapepsin-2	0	1	0	1
Pepsin A-5	0	1	0	1
Gag-Pro polyprotein	0	1	0	1
Gag-Pol polyprotein	0	1	0	1
Cathepsin E	0	1	0	1
Plasmepsin-1	0	1	0	1
Plasmepsin-2	0	1	0	1
Cathepsin D	0	3	0	3
Disintegrin and metalloproteinase domain-containing protein 9	0	1	0	1
Plasmepsin 4	0	1	0	1
Chymotrypsin-C	0	1	0	1
Protease	0	2	0	2
Bone morphogenetic protein receptor type-1B	0	0	2	2
Membrane-associated progesterone receptor component 1	0	0	1	1
Cell division cycle 7-related protein kinase	0	0	2	2
ATP-dependent RNA helicase DDX3X	0	0	2	2
Pyridoxal kinase	0	0	2	3
Citron Rho-interacting kinase	0	0	2	2
Serine/threonine-protein kinase Chk1	0	0	2	2
Aurora kinase A	0	0	2	2
Cyclin-G-associated kinase	0	0	2	2
Ephrin type-B receptor 6	0	0	2	2
Peroxisomal acyl-coenzyme A oxidase 3	0	0	2	2
Receptor-interacting serine/threonine-protein kinase 2	0	0	2	2
Mitotic checkpoint serine/threonine-protein kinase BUB1	0	0	2	2
Dynamin-like 120 kDa protein, mitochondrial	0	0	2	2
Rho-associated protein kinase 2	0	0	2	2
Serine/threonine-protein kinase ULK1	0	0	2	2
Serine/threonine-protein kinase/endoribonuclease IRE1	0	0	2	2
Ribosomal protein S6 kinase alpha-5	0	0	2	2
U5 small nuclear ribonucleoprotein 200 kDa helicase	0	0	2	2
Ribosomal protein S6 kinase alpha-4	0	0	2	2
Serine/threonine-protein kinase 16	0	0	2	2
Serine/threonine-protein kinase 10	0	0	2	2
Serine/threonine-protein kinase D3	0	1	3	4
Structural maintenance of chromosomes protein 2	0	0	2	2
Mitogen-activated protein kinase kinase kinase 6	0	0	2	2
Mitogen-activated protein kinase kinase kinase kinase 4	0	0	2	2
Serine/threonine-protein kinase LATS1	0	0	2	2
Serine/threonine-protein kinase PAK 4	0	0	2	2
Tyrosine-protein kinase ABL1	0	1	2	4
High affinity nerve growth factor receptor	0	0	2	2
Guanine nucleotide-binding protein G(i) subunit alpha-2	0	0	1	1
ADP/ATP translocase 2	0	0	2	2
Protein kinase C beta type	0	2	3	5
Insulin receptor	0	0	2	2
Glycogen phosphorylase, liver form	0	0	2	2
Tyrosine-protein kinase Fes/Fps	0	0	2	2
Macrophage colony-stimulating factor 1 receptor	0	1	0	1
Tyrosine-protein kinase Lyn	0	0	2	2
Proto-oncogene tyrosine-protein kinase receptor Ret	0	0	2	2
Insulin-like growth factor 1 receptor	0	0	2	2
Signal recognition particle receptor subunit alpha	0	0	2	2
Cytochrome c1, heme protein, mitochondrial	0	0	2	2
Hepatocyte growth factor receptor	0	1	2	3
Tyrosine-protein kinase HCK	0	0	2	2
Macrophage colony-stimulating factor 1 receptor	0	1	0	1
Platelet-derived growth factor receptor beta	0	1	2	3
Serine/threonine-protein kinase A-Raf	0	0	2	2
Mast/stem cell growth factor receptor Kit	0	1	0	1
Glycogen phosphorylase, brain form	0	0	2	2
Breakpoint cluster region protein	0	1	2	4
Fibroblast growth factor receptor 1	0	0	2	2
Cyclin-dependent kinase 4	0	0	2	2
ADP/ATP translocase 3	0	0	2	2
cAMP-dependent protein kinase type II-alpha regulatory subunit	0	0	2	2
Serine/threonine-protein kinase B-raf	0	0	2	2
Phosphorylase b kinase gamma catalytic chain, liver/testis isoform	0	0	2	2
Platelet-derived growth factor receptor alpha	0	1	0	1
Tyrosine-protein kinase Fer	0	0	2	2
Protein kinase C alpha type	0	3	4	7
cAMP-dependent protein kinase catalytic subunit alpha	0	0	2	2
General transcription and DNA repair factor IIH helicase subunit XPD	0	0	2	2
Ras-related protein Rab-6A	0	0	2	2
Ephrin type-A receptor 1	0	0	2	2
Multifunctional protein ADE2	0	0	2	2
cAMP-dependent protein kinase catalytic subunit gamma	0	0	1	1
cAMP-dependent protein kinase catalytic subunit beta	0	0	2	2
Ferrochelatase, mitochondrial	0	0	2	2
Ribosomal protein S6 kinase beta-1	0	0	2	2
Tyrosine-protein kinase JAK1	0	0	2	2
Beta-adrenergic receptor kinase 1	0	0	2	2
Probable ATP-dependent RNA helicase DDX6	0	0	2	2
Mitogen-activated protein kinase 3	0	0	2	2
MAP/microtubule affinity-regulating kinase 3	0	0	2	2
Mitogen-activated protein kinase 1	0	0	2	2
Ephrin type-A receptor 2	0	0	2	2
Ephrin type-B receptor 2	0	0	2	2
Non-receptor tyrosine-protein kinase TYK2	0	0	2	2
Wee1-like protein kinase	0	0	2	2
Heme oxygenase 2	0	0	2	2
DnaJ homolog subfamily A member 1	0	0	2	2
RAC-alpha serine/threonine-protein kinase	0	0	2	2
RAC-beta serine/threonine-protein kinase	0	0	2	2
Dual specificity protein kinase TTK	0	0	2	2
DNA replication licensing factor MCM4	0	0	2	2
Myosin-10	0	0	2	2
Vascular endothelial growth factor receptor 2	0	1	0	1
Dual specificity mitogen-activated protein kinase kinase 2	0	0	2	2
Bone morphogenetic protein receptor type-1A	0	0	2	2
Activin receptor type-1B	0	0	2	2
TGF-beta receptor type-1	0	0	2	2
TGF-beta receptor type-2	0	0	2	2
Tyrosine-protein kinase CSK	0	0	2	2
Glycine--tRNA ligase	0	0	2	2
Protein kinase C iota type	0	1	3	4
Exosome RNA helicase MTR4	0	0	2	2
Tyrosine-protein kinase Tec	0	0	2	2
Tyrosine-protein kinase ABL2	0	0	2	2
Tyrosine-protein kinase FRK	0	0	2	2
G protein-coupled receptor kinase 6	0	0	2	2
Mitogen-activated protein kinase 8	0	0	2	2
Mitogen-activated protein kinase 9	0	0	2	2
Dual specificity mitogen-activated protein kinase kinase 3	0	0	2	2
Phosphatidylinositol 5-phosphate 4-kinase type-2 alpha	0	0	2	2
Casein kinase I isoform alpha	0	0	2	2
Casein kinase I isoform delta	0	0	2	2
MAP kinase-activated protein kinase 2	0	0	2	2
Elongation factor Tu, mitochondrial	0	0	2	2
Cysteine--tRNA ligase, cytoplasmic	0	0	2	2
Casein kinase I isoform epsilon	0	0	2	2
Very long-chain specific acyl-CoA dehydrogenase, mitochondrial	0	0	2	2
Dual specificity protein kinase CLK1	0	0	2	2
Dual specificity protein kinase CLK2	0	0	2	2
Cyclin-dependent kinase 7	0	0	2	2
Cyclin-dependent kinase 9	0	0	2	2
Ras-related protein Rab-27A	0	0	2	2
Interleukin-1 receptor-associated kinase 1	0	0	2	2
Ribosomal protein S6 kinase alpha-3	0	0	2	2
Serine/threonine-protein kinase Nek2	0	0	2	2
Serine/threonine-protein kinase Nek3	0	0	2	2
Dual specificity mitogen-activated protein kinase kinase 6	0	0	2	2
LIM domain kinase 1	0	0	2	2
LIM domain kinase 2	0	0	2	2
Tyrosine--tRNA ligase, cytoplasmic	0	0	2	2
Ephrin type-B receptor 3	0	0	2	2
Ephrin type-A receptor 5	0	0	2	2
Ephrin type-B receptor 4	0	0	2	2
Ephrin type-A receptor 4	0	0	2	2
Adenosine kinase	0	0	2	2
Ras-related protein Rab-10	0	0	2	2
Actin-related protein 3	0	0	2	2
Actin-related protein 2	0	0	2	2
GTP-binding nuclear protein Ran	0	0	2	2
Casein kinase I isoform gamma-2	0	0	2	2
Cyclin-dependent kinase 3	0	0	1	1
Cyclin-dependent kinase 16	0	0	2	2
Cyclin-dependent kinase 17	0	0	2	2
Protein kinase C theta type	0	1	3	4
Activin receptor type-1	0	0	2	2
Macrophage-stimulating protein receptor	0	0	2	2
Focal adhesion kinase 1	0	0	2	2
Protein kinase C delta type	0	2	3	5
Tyrosine-protein kinase BTK	0	0	2	2
Activated CDC42 kinase 1	0	0	2	2
Epithelial discoidin domain-containing receptor 1	0	0	2	2
Mitogen-activated protein kinase kinase kinase kinase 2	0	0	2	2
Tyrosine-protein kinase Mer	0	0	2	2
Serine/threonine-protein kinase 4	0	0	2	2
Dual specificity mitogen-activated protein kinase kinase 5	0	0	2	2
Mitogen-activated protein kinase 7	0	0	2	2
Serine/threonine-protein kinase 3	0	0	2	2
Mitogen-activated protein kinase kinase kinase 1	0	0	2	2
Integrin-linked protein kinase	0	0	2	2
Rho-associated protein kinase 1	0	0	2	2
Non-receptor tyrosine-protein kinase TNK1	0	0	2	2
Calcium/calmodulin-dependent protein kinase type II subunit gamma	0	0	2	2
Calcium/calmodulin-dependent protein kinase type II subunit delta	0	0	2	2
Activin receptor type-2B	0	0	2	2
Bone morphogenetic protein receptor type-2	0	0	2	2
Protein-tyrosine kinase 6	0	0	2	2
cGMP-dependent protein kinase 1	0	0	2	2
Cyclin-dependent kinase 13	0	0	2	2
Inhibitor of nuclear factor kappa-B kinase subunit epsilon	0	0	2	2
Protein-tyrosine kinase 2-beta	0	0	2	2
Maternal embryonic leucine zipper kinase	0	0	2	2
Structural maintenance of chromosomes protein 1A	0	0	2	2
Chromodomain-helicase-DNA-binding protein 4	0	0	2	2
Peroxisomal acyl-coenzyme A oxidase 1	0	0	2	2
Ephrin type-A receptor 7	0	0	1	1
Delta(24)-sterol reductase	0	0	2	2
Dual specificity testis-specific protein kinase 1	0	0	2	2
Serine/threonine-protein kinase STK11	0	0	2	2
Serine/threonine-protein kinase N1	0	0	2	2
Serine/threonine-protein kinase N2	0	0	2	2
Calcium/calmodulin-dependent protein kinase type IV	0	0	2	2
Mitogen-activated protein kinase kinase kinase 11	0	0	2	2
MAP kinase-activated protein kinase 3	0	0	1	1
Discoidin domain-containing receptor 2	0	0	2	2
AP2-associated protein kinase 1	0	0	2	2
Myosin light chain kinase 3	0	0	2	2
Putative heat shock protein HSP 90-beta 2	0	0	2	2
Rab-like protein 3	0	0	1	1
Serine/threonine-protein kinase MRCK alpha	0	0	2	2
Serine/threonine-protein kinase MRCK gamma	0	0	2	2
Acyl-CoA dehydrogenase family member 10	0	0	2	2
Serine/threonine-protein kinase ULK3	0	0	2	2
Uncharacterized protein FLJ45252	0	0	2	2
Acyl-CoA dehydrogenase family member 11	0	0	2	2
Serine/threonine-protein kinase/endoribonuclease IRE2	0	0	2	2
Serine/threonine-protein kinase MARK2	0	0	2	2
ATP-dependent RNA helicase DHX30	0	0	2	2
Serine/threonine-protein kinase TAO1	0	0	2	2
STE20-related kinase adapter protein alpha	0	0	2	2
AarF domain-containing protein kinase 1	0	0	2	2
ATP-dependent RNA helicase DDX42	0	0	1	1
Mitogen-activated protein kinase kinase kinase kinase 3	0	0	2	2
MAP kinase-activated protein kinase 5	0	0	2	2
Atypical kinase COQ8A, mitochondrial	0	0	2	2
Phosphatidylinositol 5-phosphate 4-kinase type-2 gamma	0	0	2	2
Mitogen-activated protein kinase 15	0	0	2	2
Serine/threonine-protein kinase Nek9	0	0	2	2
ATP-dependent RNA helicase DDX1	0	0	2	2
Mitogen-activated protein kinase kinase kinase kinase 1	0	0	2	2
MAP/microtubule affinity-regulating kinase 4	0	0	2	2
Serine/threonine-protein kinase Nek1	0	0	2	2
PAS domain-containing serine/threonine-protein kinase	0	0	2	2
Calcium/calmodulin-dependent protein kinase kinase 2	0	0	2	2
EKC/KEOPS complex subunit TP53RK	0	0	2	2
Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase	0	0	2	2
Mitogen-activated protein kinase kinase kinase 5	0	0	2	2
Mitogen-activated protein kinase kinase kinase 3	0	0	2	2
Eukaryotic translation initiation factor 2-alpha kinase 1	0	0	2	2
Nucleolar GTP-binding protein 1	0	0	2	2
Serine/threonine-protein kinase D2	0	0	2	2
NUAK family SNF1-like kinase 2	0	0	1	1
RNA cytidine acetyltransferase	0	0	2	2
Serine/threonine-protein kinase SIK2	0	0	2	2
STE20-like serine/threonine-protein kinase	0	0	2	2
Serine/threonine-protein kinase TAO3	0	0	2	2
dCTP pyrophosphatase 1	0	0	2	2
Dual specificity protein kinase CLK4	0	0	2	2
Casein kinase I isoform gamma-1	0	0	2	2
Phenylalanine--tRNA ligase beta subunit	0	0	2	2
BMP-2-inducible protein kinase	0	0	2	2
Midasin	0	0	2	2
Interleukin-1 receptor-associated kinase 4	0	0	2	2
Mitogen-activated protein kinase kinase kinase 20	0	0	2	2
Cyclin-dependent kinase 12	0	0	2	2
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13	0	0	1	1
Serine/threonine-protein kinase pim-2	0	0	1	1
Serine/threonine-protein kinase 26	0	0	2	2
Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial	0	0	2	2
Serine/threonine-protein kinase NLK	0	0	2	2
Serine/threonine-protein kinase TBK1	0	0	2	2
Septin-9	0	0	2	2
Ribosomal protein S6 kinase alpha-6	0	0	2	2
TRAF2 and NCK-interacting protein kinase	0	0	2	2
Serine/threonine-protein kinase TAO2	0	0	2	2
Long-chain-fatty-acid--CoA ligase 5	0	0	1	1
ALK tyrosine kinase receptor	0	0	1	1
Serine/threonine-protein kinase ICK	0	0	2	2
RAC-gamma serine/threonine-protein kinase	0	0	2	2
Serine/threonine-protein kinase 38-like	0	0	1	1
Serine/threonine-protein kinase SIK3	0	0	2	2
Mitogen-activated protein kinase kinase kinase 2	0	0	2	2
Mitogen-activated protein kinase kinase kinase kinase 5	0	0	2	2
Receptor-interacting serine/threonine-protein kinase 3	0	0	2	2
Serine/threonine-protein kinase MRCK beta	0	0	2	2
Interleukin-1 receptor-associated kinase 3	0	0	2	2
Serine/threonine-protein kinase 24	0	0	2	2
Casein kinase I isoform gamma-3	0	0	2	2
Mitogen-activated protein kinase kinase kinase 4	0	0	2	2
Myeloblastin	0	1	0	1
Muscarinic acetylcholine receptor M1	0	1	0	1
Muscarinic acetylcholine receptor DM1	0	1	0	1
Muscarinic acetylcholine receptor M4	0	1	0	1
Muscarinic acetylcholine receptor	0	1	0	1
Muscarinic acetylcholine receptor M5	0	1	0	1
Muscarinic acetylcholine receptor M3	0	1	0	1
Muscarinic acetylcholine receptor M2	0	1	0	1
Taste receptor type 2 member 31	0	0	1	1
Taste receptor type 2 member 60	0	0	1	1
Sodium/potassium/calcium exchanger 4	0	1	1	2
Taste receptor type 2 member 14	0	0	1	1
Taste receptor type 2 member 13	0	0	1	1
Taste receptor type 2 member 9	0	0	1	1
Taste receptor type 2 member 4	0	0	1	1
Sodium/potassium/calcium exchanger 2	0	1	1	2
luciferase	0	0	0	1
Estrogen receptor	0	5	1	7
Progesterone receptor	0	3	0	4
Glucocorticoid receptor	0	1	1	2
Glucocorticoid receptor	0	0	1	1
Glutamine synthetase	0	0	1	1
Nociceptin receptor	0	0	1	1
Estrogen receptor beta	0	4	1	5
Glutamate 5-kinase	0	0	0	1
Angiotensin-converting enzyme	0	1	0	1
Chain A, Ferritin light chain	0	0	1	1
Chain A, Ferritin light chain	0	0	1	1
Chain A, Ferritin light chain	0	0	1	1
Chain A, Ferritin light chain	0	0	1	1
Chain A, Ferritin light chain	0	0	1	1
Chain A, Ferritin light chain	0	0	1	1
Chain A, Ferritin light chain	0	0	1	1
Chain A, Troponin C, slow skeletal and cardiac muscles	0	0	1	1
Chain A, Leukotriene A-4 hydrolase	0	1	0	1
Chain A, Leukotriene A-4 hydrolase	0	1	0	1
Chain A, Leukotriene A-4 hydrolase	0	1	0	1
Chain A, Leukotriene A-4 hydrolase	0	1	0	1
Chain A, Leukotriene A-4 hydrolase	0	1	0	1
Chain A, Leukotriene A-4 hydrolase	0	1	0	1
Chain A, Leukotriene A-4 hydrolase	0	1	0	1
Chain A, Leukotriene A-4 hydrolase	0	1	0	1
Chain A, Leukotriene A-4 hydrolase	0	1	0	1
Chain A, Leukotriene A-4 hydrolase	0	1	0	1
Chain A, Leukotriene A-4 hydrolase	0	1	0	1
Chain A, Leukotriene A-4 hydrolase	0	1	0	1
Chain A, Leukotriene A-4 hydrolase	0	1	0	1
Chain A, Leukotriene A-4 hydrolase	0	1	0	1
Chain A, Leukotriene A-4 hydrolase	0	1	0	1
Chain A, Leukotriene A-4 hydrolase	0	1	0	1
Chain A, Leukotriene A-4 hydrolase	0	1	0	1
M18 aspartyl aminopeptidase	0	1	0	1
cathepsin L1	0	1	0	1
Vif	0	1	0	1
transcription factor p65 isoform 1	0	0	1	1
serine/threonine-protein kinase 33 isoform a	0	0	1	1
Aryl hydrocarbon receptor	0	1	0	1
Estrogen receptor beta	0	0	1	1
Myc proto-oncogene protein	0	1	0	2
Luciferin 4-monooxygenase	0	1	1	2
DNA polymerase alpha catalytic subunit	0	1	0	1
Leukotriene A-4 hydrolase	0	1	0	1
Tyrosinase	0	3	0	3
Ornithine decarboxylase	0	1	0	1
Estrogen receptor	0	0	1	1
Endothelin receptor type B	1	0	0	1
Endothelin-1 receptor	1	0	0	1
Squalene synthase	0	1	0	1
cAMP-specific 3',5'-cyclic phosphodiesterase 4B	0	0	0	1
Bcl-2-like protein 1	0	1	0	1
N1L	0	1	0	1
NAD(P)H dehydrogenase [quinone] 1	0	0	0	3
NAD-dependent protein deacetylase sirtuin-2	0	0	1	1
NAD-dependent protein deacetylase sirtuin-1	0	0	1	3
Prenyltransferase homolog	0	0	0	1
NAD-dependent protein deacetylase sirtuin-3, mitochondrial	0	0	1	1
Chain A, 6,7-Dimethyl-8-ribityllumazine Synthase	0	0	1	1
Chain B, 6,7-Dimethyl-8-ribityllumazine Synthase	0	0	1	1
Chain H, Immunoglobulin Igg1 Heavy chain	0	0	1	1
Chain L, Immunoglobulin Igg1 Lambda Light Chain	0	0	1	1
Chain A, DODECIN	0	0	1	1
Chain A, DODECIN	0	0	1	1
Chain C, DODECIN	0	0	1	1
Chain E, DODECIN	0	0	1	1
NPYLR7B	0	0	1	1
Albumin	0	0	2	2
Beta-1 adrenergic receptor	0	2	0	2
Histamine H2 receptor	0	8	0	8
5-hydroxytryptamine receptor 2C	0	1	0	1
5-hydroxytryptamine receptor 2A	0	1	0	1
D(2) dopamine receptor	0	1	0	1
5-hydroxytryptamine receptor 2B	0	1	0	1
Multidrug and toxin extrusion protein 2	0	1	0	1
Multidrug and toxin extrusion protein 1	0	1	0	1
Met repressor	0	0	2	2
Protein arginine N-methyltransferase 5	0	0	1	1
Histone H3K27 methylase	0	0	0	1
Phenylethanolamine N-methyltransferase	0	0	1	2
S-adenosylmethionine decarboxylase proenzyme	0	1	0	2
Protein-L-isoaspartate(D-aspartate) O-methyltransferase	0	1	0	1
Catechol O-methyltransferase	0	0	0	1
Protein arginine N-methyltransferase 1	0	1	0	1
Methylosome protein 50	0	0	1	1
Pyruvate kinase PKM	0	1	1	2
Cholecystokinin receptor type A	0	1	0	1
Cholecystokinin receptor type A	0	2	2	4
Gastrin/cholecystokinin type B receptor	0	2	2	4
Gastrin/cholecystokinin type B receptor	0	2	0	2
Cholecystokinin receptor type A	0	2	0	2
Solute carrier organic anion transporter family member 1B2	0	0	0	1
Tyrosine-protein kinase JAK2	0	0	1	1
Eukaryotic translation initiation factor 5B	0	0	1	1
Cyclin-dependent kinase-like 5	0	0	1	1
Eukaryotic translation initiation factor 4E	0	0	1	1
Adenine phosphoribosyltransferase	0	0	1	1
Tyrosine-protein kinase Fgr	0	0	1	1
Peptidyl-prolyl cis-trans isomerase FKBP1A	0	1	0	1
UMP-CMP kinase	0	0	1	1
Phosphatidylethanolamine-binding protein 1	0	0	1	1
S-adenosylmethionine synthase isoform type-2	0	0	1	1
Serine/threonine-protein kinase receptor R3	0	0	1	1
Electron transfer flavoprotein subunit beta	0	0	1	1
Choline-phosphate cytidylyltransferase A	0	0	1	1
Dual specificity protein kinase CLK3	0	0	1	1
Peptidyl-prolyl cis-trans isomerase FKBP1B	0	0	2	2
ATP-dependent 6-phosphofructokinase, platelet type	0	0	1	1
Protein kinase C zeta type	0	1	2	3
Cyclin-dependent kinase 18	0	0	1	1
Serine/threonine-protein kinase PAK 2	0	0	1	1
Peptidyl-prolyl cis-trans isomerase FKBP5	0	2	0	2
Uncharacterized aarF domain-containing protein kinase 5	0	0	1	1
Programmed cell death protein 4	0	0	1	1
Serine/threonine-protein kinase N3	0	0	1	1
Myosin-14	0	0	1	1
Regulatory-associated protein of mTOR	0	1	0	1
Misshapen-like kinase 1	0	0	1	1
Calcium/calmodulin-dependent protein kinase type 1G	0	0	1	1
Dual specificity testis-specific protein kinase 2	0	0	1	1
Target of rapamycin complex subunit LST8	0	1	0	1
Serine/threonine-protein kinase mTOR	0	1	0	1
Isoleucine--tRNA ligase, mitochondrial	0	0	1	1
Obg-like ATPase 1	0	0	1	1
Thyroid hormone receptor-associated protein 3	0	0	1	1
Dual specificity tyrosine-phosphorylation-regulated kinase 1B	0	0	1	1
Bifunctional epoxide hydrolase 2	0	1	0	1
C-X-C chemokine receptor type 5 isoform 1	0	1	0	1
ubiquitin-conjugating enzyme E2 N	0	2	0	2
C-C chemokine receptor type 6	0	1	0	1
bcl-2-related protein A1	0	1	0	1
Endoglycoceramidase II	0	0	0	1
Protein kinase C alpha type	0	2	0	2
Protein kinase C delta type	0	2	0	2
Protein kinase C epsilon type	0	2	0	2
Protein kinase C zeta type	0	2	0	2
cAMP-dependent protein kinase catalytic subunit alpha	0	1	0	1
Protein kinase C gamma type	0	2	0	2
Protein kinase C beta type	0	2	0	2
Protein kinase C eta type	0	2	0	2
Protein kinase C theta type	0	2	0	2
Chain A, Ribosomal protein S6 kinase alpha-1	0	1	0	1
Chain X, Tyrosine-protein kinase Lyn	0	1	0	1
Chain A, Dual specificity protein kinase TTK	0	0	1	1
Chain A, Dual specificity protein kinase TTK	0	0	1	1
Chain A, Protein (aspartate Aminotransferase)	0	0	1	1
Chain A, Aspartate Aminotransferase	0	0	1	1
Lysine-specific demethylase 4E	0	1	0	1
Delta-aminolevulinic acid dehydratase	0	1	0	1
NADP-dependent malic enzyme, mitochondrial	0	0	0	1
Solute carrier family 13 member 3	0	1	0	1
Chain A, MALTOPORIN	0	0	1	1
Chain B, MALTOPORIN	0	0	1	1
UDP-glucuronosyltransferase 2B7	0	1	0	3
Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform	0	2	0	2
Splicing factor 3B subunit 3	0	1	0	1
Chain A, CES1 protein	0	1	0	1
DNA polymerase III, partial	1	0	0	1
interferon gamma precursor	0	0	0	1
Receptor tyrosine-protein kinase erbB-2	0	1	0	1
Protein kinase C gamma type	0	2	1	3
Steroid hormone receptor ERR1	0	1	0	1
Transcriptional activator protein LuxR	0	1	0	1
Substance-K receptor	0	2	0	2
Protein kinase C eta type	0	1	1	2
Substance-P receptor	0	2	0	2
B2 bradykinin receptor	0	2	0	2
Melanocortin receptor 4	0	2	0	2
Melanocortin receptor 5	0	2	0	2
Melanocortin receptor 3	0	2	0	2
Estrogen-related receptor gamma	0	1	0	1
Phospholipase D1	0	1	0	1
Protein kinase C epsilon type	0	2	1	3
Platelet-activating factor acetylhydrolase	0	1	0	2
Phospholipase D1	0	1	0	1
Serine/threonine-protein kinase D1	0	1	1	2
Emopamil-binding protein-like	0	1	0	1
7-dehydrocholesterol reductase	0	1	1	2
Solute carrier organic anion transporter family member 1A4	0	0	0	2
Solute carrier organic anion transporter family member 1A5	0	0	0	2
Sodium/bile acid cotransporter	0	0	0	2
Ileal sodium/bile acid cotransporter	0	2	0	2
G-protein coupled bile acid receptor 1	0	0	2	2
Bile salt export pump	0	0	0	1
Dihydroorotate dehydrogenase	0	1	0	1
Dihydroorotate dehydrogenase (quinone), mitochondrial	0	1	0	1
Dihydrofolate reductase	0	3	0	3
Dihydroorotate dehydrogenase (quinone), mitochondrial	0	2	1	3
Stromal interaction molecule 1	0	1	0	1
Dihydroorotate dehydrogenase	0	2	0	2
Dihydroorotate dehydrogenase (quinone), mitochondrial	0	1	0	1
Calcium release-activated calcium channel protein 1	0	1	0	1
Ras guanyl-releasing protein 3	0	0	1	1
Snq2p	0	0	0	1
D(1B) dopamine receptor	0	1	0	1
Histamine H1 receptor	0	1	0	1
Pleiotropic ABC efflux transporter of multiple drugs	0	1	0	2
Aldehyde oxidase	0	1	0	3
Mucosa-associated lymphoid tissue lymphoma translocation protein 1	0	1	0	1
Thymidine kinase	0	1	0	2
Thymidine kinase	0	1	0	2
Thymidylate synthase	0	0	0	1
Thymidine phosphorylase	0	0	0	1
Thymidine phosphorylase	0	0	0	1
Thymidylate kinase	0	1	0	1
Thymidine kinase, cytosolic	0	0	0	2
Thymidine kinase	0	0	0	1
Thymidylate kinase	0	1	0	1
Thymidine kinase	0	1	0	2
Thymidine kinase	0	0	0	1
Thymidine kinase	0	0	0	1
Chain A, Trp Rna-binding Attenuation Protein	0	0	1	1
Chain K, Trp Rna-binding Attenuation Protein	0	0	1	1
Chain B, tryptophanyl-tRNA synthetase	0	0	1	1
Chain C, Tryptophanyl-tRNA synthetase II	0	0	1	1
Indoleamine 2,3-dioxygenase 1	0	2	0	3
Tryptophan 2,3-dioxygenase	0	1	0	2
Uracil nucleotide/cysteinyl leukotriene receptor	0	1	0	1
Tryprostatin B synthase	0	0	0	1
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase	0	0	1	1
Chain A, Glycogen phosphorylase, liver form	0	0	1	1
Chain A, glycogen phosphorylase, liver form	0	0	1	1
Chain A, Glycogen phosphorylase, liver form	0	0	1	1
Chain A, Glycogen phosphorylase, liver form	0	0	1	1
Solute carrier family 22 member 6	0	0	0	1
Solute carrier family 22 member 8	0	1	0	1
Solute carrier organic anion transporter family member 1A2	0	0	0	1
Ectonucleotide pyrophosphatase/phosphodiesterase family member 2	0	1	0	1
Cocaine esterase	0	1	0	1
Aldo-keto reductase family 1 member A1	0	1	0	1
UDP-glucuronosyltransferase 1-6	0	0	0	1
Liver carboxylesterase 1	0	1	0	1
Aldo-keto reductase family 1 member A1	0	1	0	1
Aldo-keto reductase family 1 member A1	0	1	0	1
Aldo-keto reductase family 1 member B7	0	1	0	1
NAD-dependent protein deacylase sirtuin-5, mitochondrial	0	1	0	1
Receptor-type tyrosine-protein phosphatase F	0	1	0	1
Tyrosine-protein phosphatase non-receptor type 2	0	1	0	1
Tyrosine-protein phosphatase non-receptor type 6	0	1	0	1
Tyrosine-protein phosphatase non-receptor type 11	0	1	0	1
Glycoprotein	0	1	0	1
Muscarinic acetylcholine receptor M2	0	0	1	1
Catechol O-methyltransferase	0	1	0	1
Potassium voltage-gated channel subfamily A member 3	0	1	0	1
Chloroquine resistance transporter	0	1	0	1
Aldehyde oxidase 1	0	1	0	1
fructose-bisphosphate aldolase A	1	0	0	1
glyceraldehyde-3-phosphate dehydrogenase isoform 1	1	0	0	1
Glutathione reductase	0	0	0	1
Aldehyde oxidase 1	0	1	0	1
Dihydrolipoyl dehydrogenase, mitochondrial	0	0	0	1
Ubiquitin carboxyl-terminal hydrolase isozyme L1	0	1	0	1
Ubiquitin carboxyl-terminal hydrolase isozyme L3	0	1	0	1
NAD	0	0	0	2
Protein-glutamine gamma-glutamyltransferase 2	0	1	0	1
Dual specificity protein phosphatase 1	0	1	0	1
Trypanothione reductase	0	1	0	3
M-phase inducer phosphatase 1	0	1	0	1
M-phase inducer phosphatase 2	0	1	0	1
M-phase inducer phosphatase 3	0	1	0	1
Tyrosine-protein kinase JAK3	0	1	0	1
Aldehyde oxidase 1	0	1	0	1
DNA gyrase subunit B	0	1	0	1
DNA gyrase subunit A	0	1	0	1
Receptor-type tyrosine-protein phosphatase eta	0	1	0	1
Receptor protein-tyrosine kinase	0	1	0	1
Aldehyde oxidase 1	0	1	0	1
Dual specificity protein phosphatase 6	0	1	0	1
Ubiquitin carboxyl-terminal hydrolase isozyme L3	0	1	0	1
Ubiquitin carboxyl-terminal hydrolase isozyme L1	0	1	0	1
Aldehyde oxidase 1	0	1	0	1
Carbonic anhydrase	0	0	0	1
Carbonic anhydrase	0	1	0	1
Carbonic anhydrase	0	1	0	1
Carbonic anhydrase	0	1	0	1
Carbonic anhydrase	0	1	0	1
Carbonic anhydrase	0	1	0	1
Prolyl endopeptidase	0	1	0	1
Carbonic anhydrase 2	0	1	0	1
Translocator protein	0	1	0	1
Arachidonate 5-lipoxygenase-activating protein	0	1	0	1
Carbonic anhydrase	0	1	0	1
Carbonic anhydrase 2	0	1	0	1
Carbonic anhydrase, alpha family	0	1	0	1
Carbonic anhydrase	0	1	0	1
Delta carbonic anhydrase	0	1	0	1
Amine oxidase [flavin-containing]	0	1	0	1
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]

Adult Neuronal Ceroid Lipofuscinosis

Synonyms(44)

Research Excerpts

Overview

Treatment

Research

Studies (378)

Protein Targets (2,107)

Adult Neuronal Ceroid Lipofuscinosis

Synonyms(44)

Research Excerpts

Overview

Treatment

Research

Studies (378)

Drugs Studied (279)

Protein Targets (2,107)