| Protein | Potency Measurements | Inhibition Measurements | Activation Measurements | Drugs |
|---|
| Chain A, TYROSYL-DNA PHOSPHODIESTERASE | 4 | 0 | 0 | 4 |
| Chain A, Putative fructose-1,6-bisphosphate aldolase | 3 | 0 | 0 | 3 |
| Chain A, HADH2 protein | 3 | 0 | 0 | 3 |
| Chain B, HADH2 protein | 3 | 0 | 0 | 3 |
| Chain A, 2-oxoglutarate Oxygenase | 5 | 0 | 0 | 5 |
| Chain A, Cruzipain | 1 | 0 | 0 | 1 |
| phosphopantetheinyl transferase | 5 | 0 | 0 | 5 |
| USP1 protein, partial | 3 | 0 | 0 | 3 |
| Microtubule-associated protein tau | 3 | 0 | 0 | 3 |
| aldehyde dehydrogenase 1 family, member A1 | 3 | 0 | 0 | 3 |
| vitamin D3 receptor isoform VDRA | 2 | 0 | 0 | 2 |
| DNA polymerase kappa isoform 1 | 2 | 0 | 0 | 2 |
| caspase-1 isoform alpha precursor | 1 | 0 | 0 | 1 |
| lamin isoform A-delta10 | 5 | 0 | 0 | 5 |
| Caspase-7 | 1 | 0 | 0 | 1 |
| Inositol monophosphatase 1 | 3 | 0 | 0 | 3 |
| Solute carrier organic anion transporter family member 1B3 | 0 | 2 | 0 | 3 |
| Solute carrier organic anion transporter family member 1B1 | 0 | 2 | 0 | 3 |
| Chain A, MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASE | 3 | 0 | 0 | 3 |
| Chain A, Dihydrofolate reductase | 0 | 0 | 1 | 1 |
| Chain A, Ferritin light chain | 3 | 0 | 0 | 3 |
| acid sphingomyelinase | 1 | 0 | 0 | 1 |
| glp-1 receptor, partial | 2 | 0 | 0 | 2 |
| GLI family zinc finger 3 | 4 | 0 | 0 | 4 |
| AR protein | 4 | 0 | 0 | 4 |
| thyroid stimulating hormone receptor | 2 | 0 | 0 | 2 |
| retinoid X nuclear receptor alpha | 3 | 0 | 0 | 3 |
| estrogen-related nuclear receptor alpha | 2 | 0 | 0 | 2 |
| estrogen nuclear receptor alpha | 6 | 0 | 0 | 6 |
| glucocerebrosidase | 1 | 0 | 0 | 1 |
| vitamin D (1,25- dihydroxyvitamin D3) receptor | 1 | 0 | 0 | 1 |
| alpha-galactosidase | 1 | 0 | 0 | 1 |
| activating transcription factor 6 | 2 | 0 | 0 | 2 |
| lysosomal alpha-glucosidase preproprotein | 2 | 0 | 0 | 2 |
| 15-hydroxyprostaglandin dehydrogenase [NAD(+)] isoform 1 | 2 | 0 | 0 | 2 |
| nuclear factor erythroid 2-related factor 2 isoform 2 | 2 | 0 | 0 | 2 |
| DNA polymerase beta | 3 | 0 | 0 | 3 |
| Multidrug resistance-associated protein 4 | 0 | 4 | 0 | 5 |
| Bile salt export pump | 0 | 5 | 0 | 5 |
| Cellular tumor antigen p53 | 3 | 0 | 0 | 3 |
| Thymidylate synthase | 0 | 2 | 0 | 2 |
| Thymidylate synthase | 0 | 1 | 0 | 1 |
| Dihydrofolate reductase | 0 | 0 | 1 | 1 |
| Aldo-keto reductase family 1 member B1 | 0 | 1 | 0 | 1 |
| Alpha-synuclein | 2 | 0 | 0 | 2 |
| Folylpolyglutamate synthase, mitochondrial | 0 | 0 | 0 | 1 |
| Solute carrier organic anion transporter family member 1A3 | 0 | 1 | 0 | 1 |
| Folylpolyglutamate synthase, mitochondrial | 0 | 0 | 0 | 1 |
| Multidrug resistance associated protein | 0 | 0 | 0 | 1 |
| N(G),N(G)-dimethylarginine dimethylaminohydrolase 1 | 0 | 1 | 0 | 1 |
| Smad3 | 2 | 0 | 0 | 2 |
| chromobox protein homolog 1 | 2 | 0 | 0 | 2 |
| ATP-binding cassette sub-family C member 3 | 0 | 4 | 0 | 4 |
| Type-1A angiotensin II receptor | 0 | 1 | 0 | 1 |
| Type-1B angiotensin II receptor | 0 | 2 | 0 | 2 |
| Type-2 angiotensin II receptor | 0 | 1 | 0 | 1 |
| cGMP-inhibited 3',5'-cyclic phosphodiesterase B | 0 | 1 | 0 | 1 |
| cGMP-inhibited 3',5'-cyclic phosphodiesterase A | 0 | 2 | 0 | 2 |
| 5-hydroxytryptamine receptor 1A | 0 | 1 | 0 | 1 |
| Type-1 angiotensin II receptor | 0 | 1 | 0 | 1 |
| TDP1 protein | 2 | 0 | 0 | 2 |
| glucocorticoid receptor [Homo sapiens] | 2 | 0 | 0 | 2 |
| euchromatic histone-lysine N-methyltransferase 2 | 4 | 0 | 0 | 4 |
| potassium voltage-gated channel subfamily H member 2 isoform d | 1 | 0 | 0 | 1 |
| thyroid hormone receptor beta isoform 2 | 3 | 0 | 0 | 3 |
| geminin | 5 | 0 | 0 | 5 |
| interleukin 8 | 1 | 0 | 0 | 1 |
| thioredoxin reductase | 2 | 0 | 0 | 2 |
| ClpP | 1 | 0 | 0 | 1 |
| RAR-related orphan receptor gamma | 2 | 0 | 0 | 2 |
| ATAD5 protein, partial | 3 | 0 | 0 | 3 |
| caspase 7, apoptosis-related cysteine protease | 2 | 0 | 0 | 2 |
| nuclear receptor subfamily 1, group I, member 3 | 2 | 0 | 0 | 2 |
| regulator of G-protein signaling 4 | 2 | 0 | 0 | 2 |
| EWS/FLI fusion protein | 2 | 0 | 0 | 2 |
| retinoic acid nuclear receptor alpha variant 1 | 2 | 0 | 0 | 2 |
| pregnane X nuclear receptor | 2 | 0 | 0 | 2 |
| caspase-3 | 2 | 0 | 0 | 2 |
| aryl hydrocarbon receptor | 2 | 0 | 0 | 2 |
| cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a | 3 | 0 | 0 | 3 |
| Bloom syndrome protein isoform 1 | 2 | 0 | 0 | 2 |
| cytochrome P450 2D6 isoform 1 | 1 | 0 | 0 | 1 |
| peripheral myelin protein 22 isoform 1 | 2 | 0 | 0 | 2 |
| ras-related protein Rab-9A | 1 | 0 | 0 | 1 |
| cytochrome P450 3A4 isoform 1 | 1 | 0 | 0 | 1 |
| M-phase phosphoprotein 8 | 1 | 0 | 0 | 1 |
| muscarinic acetylcholine receptor M1 | 2 | 0 | 0 | 2 |
| Gamma-aminobutyric acid receptor subunit pi | 1 | 0 | 0 | 1 |
| Cytochrome P450 1A1 | 0 | 1 | 0 | 1 |
| Cytochrome P450 1A2 | 0 | 1 | 0 | 1 |
| Myeloperoxidase | 0 | 1 | 0 | 1 |
| Cytochrome P450 1A2 | 0 | 1 | 0 | 1 |
| Cholinesterase | 0 | 2 | 0 | 2 |
| Cytochrome P450 2C11 | 0 | 1 | 0 | 1 |
| Cytochrome P450 2D6 | 0 | 1 | 0 | 1 |
| Aromatase | 0 | 1 | 0 | 1 |
| Gamma-aminobutyric acid receptor subunit beta-1 | 1 | 0 | 0 | 1 |
| Ribosyldihydronicotinamide dehydrogenase [quinone] | 0 | 2 | 0 | 2 |
| Gamma-aminobutyric acid receptor subunit delta | 1 | 0 | 0 | 1 |
| Gamma-aminobutyric acid receptor subunit gamma-2 | 1 | 0 | 0 | 1 |
| Gamma-aminobutyric acid receptor subunit alpha-5 | 1 | 0 | 0 | 1 |
| Gamma-aminobutyric acid receptor subunit alpha-3 | 1 | 0 | 0 | 1 |
| Acetylcholinesterase | 0 | 2 | 0 | 2 |
| Metabotropic glutamate receptor 1 | 0 | 1 | 0 | 1 |
| Gamma-aminobutyric acid receptor subunit gamma-1 | 1 | 0 | 0 | 1 |
| Gamma-aminobutyric acid receptor subunit alpha-2 | 1 | 0 | 0 | 1 |
| Acetylcholinesterase | 0 | 1 | 0 | 1 |
| Gamma-aminobutyric acid receptor subunit alpha-4 | 1 | 0 | 0 | 1 |
| Gamma-aminobutyric acid receptor subunit gamma-3 | 1 | 0 | 0 | 1 |
| Gamma-aminobutyric acid receptor subunit alpha-6 | 1 | 0 | 0 | 1 |
| Mu-type opioid receptor | 0 | 1 | 0 | 1 |
| Nociceptin receptor | 0 | 1 | 0 | 1 |
| Alpha-1A adrenergic receptor | 0 | 2 | 0 | 2 |
| Melatonin receptor type 1A | 0 | 2 | 1 | 3 |
| Melatonin receptor type 1C | 0 | 0 | 1 | 1 |
| Melatonin receptor type 1A | 0 | 1 | 1 | 2 |
| Melatonin receptor type 1B | 0 | 2 | 1 | 3 |
| Melatonin receptor type 1C | 0 | 1 | 1 | 2 |
| Melatonin receptor type 1B | 0 | 1 | 1 | 2 |
| Nuclear receptor ROR-gamma | 1 | 0 | 0 | 1 |
| Gamma-aminobutyric acid receptor subunit alpha-1 | 1 | 0 | 0 | 1 |
| Gamma-aminobutyric acid receptor subunit beta-3 | 1 | 0 | 0 | 1 |
| Gamma-aminobutyric acid receptor subunit beta-2 | 1 | 0 | 0 | 1 |
| Nuclear factor erythroid 2-related factor 2 | 0 | 0 | 0 | 1 |
| Cytochrome P450 1B1 | 0 | 1 | 0 | 1 |
| Palmitoleoyl-protein carboxylesterase NOTUM | 0 | 1 | 0 | 1 |
| GABA theta subunit | 1 | 0 | 0 | 1 |
| Canalicular multispecific organic anion transporter 1 | 0 | 3 | 0 | 3 |
| Gamma-aminobutyric acid receptor subunit epsilon | 1 | 0 | 0 | 1 |
| Carboxylic ester hydrolase | 0 | 1 | 0 | 1 |
| Histamine H3 receptor | 0 | 1 | 0 | 1 |
| ATP-dependent phosphofructokinase | 2 | 0 | 0 | 2 |
| nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105), isoform CRA_a | 2 | 0 | 0 | 2 |
| histone acetyltransferase KAT2A isoform 1 | 2 | 0 | 0 | 2 |
| Solute carrier family 22 member 2 | 0 | 1 | 0 | 1 |
| Solute carrier family 22 member 1 | 0 | 1 | 0 | 1 |
| Dihydrofolate reductase | 0 | 1 | 0 | 1 |
| Dipeptidyl peptidase 4 | 0 | 1 | 0 | 1 |
| Solute carrier family 22 member 1 | 0 | 0 | 0 | 1 |
| Multidrug and toxin extrusion protein 1 | 0 | 1 | 0 | 1 |
| Chain E, Fibrin beta chain | 0 | 1 | 0 | 1 |
| Chain A, JmjC domain-containing histone demethylation protein 3A | 1 | 0 | 0 | 1 |
| Chain A, ATP-DEPENDENT DNA HELICASE Q1 | 1 | 0 | 0 | 1 |
| Luciferase | 2 | 0 | 0 | 2 |
| T cell receptor, partial | 1 | 0 | 0 | 1 |
| acetylcholinesterase | 1 | 0 | 0 | 1 |
| luteinizing hormone receptor | 1 | 0 | 0 | 1 |
| integrase, partial | 0 | 1 | 0 | 1 |
| chaperonin-containing TCP-1 beta subunit homolog | 1 | 0 | 0 | 1 |
| lens epithelium-derived growth factor p75 | 0 | 1 | 0 | 1 |
| hypoxia-inducible factor 1 alpha subunit | 1 | 0 | 0 | 1 |
| Caspase 6, apoptosis-related cysteine peptidase | 0 | 0 | 0 | 1 |
| SMAD family member 2 | 1 | 0 | 0 | 1 |
| Fumarate hydratase | 1 | 0 | 0 | 1 |
| PPM1D protein | 1 | 0 | 0 | 1 |
| SMAD family member 3 | 1 | 0 | 0 | 1 |
| TSHR protein | 1 | 0 | 0 | 1 |
| Apoptotic peptidase activating factor 1 | 0 | 1 | 0 | 1 |
| thioredoxin glutathione reductase | 1 | 0 | 0 | 1 |
| estrogen receptor 2 (ER beta) | 1 | 0 | 0 | 1 |
| hypothetical protein, conserved | 1 | 0 | 0 | 1 |
| progesterone receptor | 1 | 0 | 0 | 1 |
| isocitrate dehydrogenase 1, partial | 1 | 0 | 0 | 1 |
| cytochrome P450 family 3 subfamily A polypeptide 4 | 1 | 0 | 0 | 1 |
| farnesoid X nuclear receptor | 1 | 0 | 0 | 1 |
| G | 1 | 0 | 0 | 1 |
| cytochrome P450 2D6 | 1 | 0 | 0 | 1 |
| polyprotein | 1 | 0 | 0 | 1 |
| luciferase | 1 | 0 | 0 | 1 |
| bromodomain adjacent to zinc finger domain 2B | 1 | 0 | 0 | 1 |
| peroxisome proliferator-activated receptor delta | 1 | 0 | 0 | 1 |
| peroxisome proliferator activated receptor gamma | 1 | 0 | 0 | 1 |
| IDH1 | 1 | 0 | 0 | 1 |
| thyroid stimulating hormone receptor | 1 | 0 | 0 | 1 |
| v-jun sarcoma virus 17 oncogene homolog (avian) | 1 | 0 | 0 | 1 |
| Histone H2A.x | 2 | 0 | 0 | 2 |
| serine-protein kinase ATM isoform a | 1 | 0 | 0 | 1 |
| neutrophil cytosol factor 1 | 0 | 1 | 0 | 1 |
| thyroid hormone receptor beta isoform a | 1 | 0 | 0 | 1 |
| parathyroid hormone/parathyroid hormone-related peptide receptor precursor | 1 | 0 | 0 | 1 |
| caspase-9 isoform alpha precursor | 0 | 1 | 0 | 1 |
| histone deacetylase 9 isoform 3 | 1 | 0 | 0 | 1 |
| heat shock protein beta-1 | 1 | 0 | 0 | 1 |
| huntingtin isoform 2 | 1 | 0 | 0 | 1 |
| pyruvate kinase PKM isoform a | 1 | 0 | 0 | 1 |
| mitogen-activated protein kinase 1 | 1 | 0 | 0 | 1 |
| flap endonuclease 1 | 1 | 0 | 0 | 1 |
| caspase-3 isoform a preproprotein | 0 | 1 | 0 | 1 |
| protein AF-9 isoform a | 0 | 0 | 0 | 1 |
| histone-lysine N-methyltransferase 2A isoform 2 precursor | 1 | 0 | 0 | 1 |
| nuclear factor erythroid 2-related factor 2 isoform 1 | 1 | 0 | 0 | 1 |
| peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 | 1 | 0 | 0 | 1 |
| DNA polymerase eta isoform 1 | 1 | 0 | 0 | 1 |
| DNA polymerase iota isoform a (long) | 3 | 0 | 0 | 3 |
| urokinase-type plasminogen activator precursor | 1 | 0 | 0 | 1 |
| plasminogen precursor | 1 | 0 | 0 | 1 |
| urokinase plasminogen activator surface receptor precursor | 1 | 0 | 0 | 1 |
| Vpr | 1 | 0 | 0 | 1 |
| survival motor neuron protein isoform d | 2 | 0 | 0 | 2 |
| muscleblind-like protein 1 isoform 1 | 1 | 0 | 0 | 1 |
| replicative DNA helicase | 0 | 0 | 0 | 1 |
| recombinase A | 0 | 0 | 1 | 1 |
| POsterior Segregation | 0 | 0 | 1 | 1 |
| DNA repair protein RAD52 homolog isoform a | 0 | 0 | 0 | 1 |
| neuropeptide S receptor isoform A | 1 | 0 | 0 | 1 |
| Glutathione reductase | 0 | 1 | 0 | 1 |
| Voltage-dependent calcium channel gamma-2 subunit | 1 | 0 | 0 | 1 |
| Glutathione reductase, mitochondrial | 0 | 1 | 0 | 2 |
| Glycoprotein hormones alpha chain | 1 | 0 | 0 | 1 |
| Interferon beta | 1 | 0 | 0 | 1 |
| HLA class I histocompatibility antigen, B alpha chain | 1 | 0 | 0 | 1 |
| Albumin | 0 | 0 | 0 | 1 |
| Amyloid-beta precursor protein | 0 | 1 | 0 | 1 |
| Dihydrolipoyl dehydrogenase, mitochondrial | 0 | 1 | 0 | 2 |
| Microtubule-associated protein tau | 0 | 1 | 1 | 2 |
| Alpha-1B adrenergic receptor | 0 | 1 | 0 | 1 |
| Glutamate receptor 2 | 1 | 0 | 0 | 1 |
| Amine oxidase [flavin-containing] A | 0 | 1 | 0 | 1 |
| Alpha-1D adrenergic receptor | 0 | 1 | 0 | 1 |
| Sodium-dependent noradrenaline transporter | 0 | 0 | 1 | 1 |
| Cruzipain | 0 | 1 | 0 | 1 |
| Spike glycoprotein | 2 | 0 | 0 | 2 |
| Guanine nucleotide-binding protein G | 1 | 0 | 0 | 1 |
| TAR DNA-binding protein 43 | 1 | 0 | 0 | 1 |
| Thioredoxin reductase 1, cytoplasmic | 0 | 1 | 0 | 2 |
| Dihydrolipoyl dehydrogenase | 0 | 1 | 0 | 2 |
| Inositol hexakisphosphate kinase 1 | 1 | 0 | 0 | 1 |
| ATPase family AAA domain-containing protein 5 | 1 | 0 | 0 | 1 |
| Ataxin-2 | 1 | 0 | 0 | 1 |
| Zinc finger protein mex-5 | 0 | 0 | 1 | 1 |
| cytochrome P450 2C9, partial | 1 | 0 | 0 | 1 |
| phosphoglycerate kinase | 1 | 0 | 0 | 1 |
| endonuclease IV | 1 | 0 | 0 | 1 |
| dopamine D1 receptor | 1 | 0 | 0 | 1 |
| NFKB1 protein, partial | 1 | 0 | 0 | 1 |
| arylsulfatase A | 1 | 0 | 0 | 1 |
| vasopressin V1b receptor | 1 | 0 | 0 | 1 |
| ubiquitin carboxyl-terminal hydrolase 2 isoform a | 1 | 0 | 0 | 1 |
| relaxin receptor 1 isoform 1 | 1 | 0 | 0 | 1 |
| cGMP-dependent 3',5'-cyclic phosphodiesterase | 0 | 1 | 0 | 1 |
| High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8A | 0 | 1 | 0 | 1 |
| cGMP-specific 3',5'-cyclic phosphodiesterase | 0 | 1 | 0 | 1 |
| Tumor necrosis factor | 0 | 1 | 0 | 1 |
| cAMP-specific 3',5'-cyclic phosphodiesterase 4A | 0 | 1 | 0 | 1 |
| Adenosine receptor A2b | 0 | 1 | 0 | 1 |
| Disintegrin and metalloproteinase domain-containing protein 17 | 1 | 0 | 0 | 1 |
| cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 0 | 1 | 0 | 1 |
| cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 0 | 1 | 0 | 1 |
| Chitotriosidase-1 | 0 | 2 | 1 | 3 |
| Endochitinase B1 | 0 | 2 | 1 | 3 |
| Chain A, Protocatechuate 3,4-dioxygenase alpha chain | 0 | 0 | 1 | 1 |
| Chain B, Protocatechuate 3,4-dioxygenase beta chain | 0 | 0 | 1 | 1 |
| GLS protein | 1 | 0 | 0 | 1 |
| M18 aspartyl aminopeptidase | 0 | 1 | 0 | 1 |
| cathepsin L1 | 0 | 1 | 0 | 1 |
| lethal(3)malignant brain tumor-like protein 1 isoform I | 1 | 0 | 0 | 1 |
| Polyphenol oxidase 2 | 0 | 1 | 0 | 1 |
| Carbonic anhydrase 12 | 0 | 1 | 0 | 1 |
| Rap guanine nucleotide exchange factor 3 | 1 | 0 | 0 | 1 |
| Carbonic anhydrase 1 | 0 | 1 | 0 | 1 |
| Carbonic anhydrase 2 | 0 | 1 | 0 | 1 |
| 3-dehydroquinate synthase | 0 | 1 | 0 | 1 |
| 72 kDa type IV collagenase | 0 | 1 | 0 | 1 |
| Matrilysin | 0 | 1 | 0 | 1 |
| Prolyl 4-hydroxylase subunit alpha-1 | 0 | 1 | 0 | 1 |
| Carbonic anhydrase 4 | 0 | 1 | 0 | 1 |
| Carbonic anhydrase 6 | 0 | 1 | 0 | 1 |
| Carbonic anhydrase 7 | 0 | 1 | 0 | 1 |
| 4-galactosyl-N-acetylglucosaminide 3-alpha-L-fucosyltransferase FUT6 | 0 | 1 | 0 | 1 |
| Alpha-glucosidase MAL12 | 0 | 1 | 0 | 1 |
| Anthrax toxin receptor 2 | 0 | 1 | 0 | 1 |
| Xanthine dehydrogenase/oxidase | 0 | 1 | 0 | 1 |
| Alpha-(1,3)-fucosyltransferase 7 | 0 | 1 | 0 | 1 |
| CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 1 | 0 | 1 | 0 | 1 |
| Carbonic anhydrase 9 | 0 | 1 | 0 | 1 |
| Carbonic anhydrase | 0 | 1 | 0 | 1 |
| Dihydroorotate dehydrogenase | 0 | 1 | 0 | 1 |
| Carbonic anhydrase 14 | 0 | 1 | 0 | 1 |
| [prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023] |