| Protein | Potency Measurements | Inhibition Measurements | Activation Measurements | Drugs |
|---|
| Chain A, MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASE | 3 | 0 | 0 | 3 |
| Luciferase | 2 | 0 | 0 | 2 |
| RAR-related orphan receptor gamma | 3 | 0 | 0 | 3 |
| retinoid X nuclear receptor alpha | 2 | 0 | 0 | 2 |
| G | 1 | 0 | 0 | 1 |
| peroxisome proliferator activated receptor gamma | 2 | 0 | 0 | 2 |
| euchromatic histone-lysine N-methyltransferase 2 | 4 | 0 | 0 | 4 |
| thyroid stimulating hormone receptor | 1 | 0 | 0 | 1 |
| chromobox protein homolog 1 | 3 | 0 | 0 | 3 |
| parathyroid hormone/parathyroid hormone-related peptide receptor precursor | 1 | 0 | 0 | 1 |
| geminin | 3 | 0 | 0 | 3 |
| muscleblind-like protein 1 isoform 1 | 2 | 0 | 0 | 2 |
| Interferon beta | 1 | 0 | 0 | 1 |
| HLA class I histocompatibility antigen, B alpha chain | 1 | 0 | 0 | 1 |
| Guanine nucleotide-binding protein G | 2 | 0 | 0 | 2 |
| Inositol hexakisphosphate kinase 1 | 1 | 0 | 0 | 1 |
| cytochrome P450 2C9, partial | 1 | 0 | 0 | 1 |
| Chain A, TYROSYL-DNA PHOSPHODIESTERASE | 2 | 0 | 0 | 2 |
| Chain A, Phospholipase A2 isoform 3 | 0 | 0 | 1 | 1 |
| Chain A, HADH2 protein | 2 | 0 | 0 | 2 |
| Chain B, HADH2 protein | 2 | 0 | 0 | 2 |
| Chain A, 2-oxoglutarate Oxygenase | 1 | 0 | 0 | 1 |
| GTP-binding protein (rab7) | 0 | 0 | 1 | 1 |
| ras protein, partial | 0 | 0 | 1 | 1 |
| interleukin 8 | 1 | 0 | 0 | 1 |
| thioredoxin reductase | 2 | 0 | 0 | 2 |
| GLS protein | 2 | 0 | 0 | 2 |
| AR protein | 4 | 0 | 0 | 4 |
| aldehyde dehydrogenase 1 family, member A1 | 3 | 0 | 0 | 3 |
| thyroid stimulating hormone receptor | 3 | 0 | 0 | 3 |
| hypothetical protein, conserved | 1 | 0 | 0 | 1 |
| cytochrome P450 family 3 subfamily A polypeptide 4 | 1 | 0 | 0 | 1 |
| EWS/FLI fusion protein | 2 | 0 | 0 | 2 |
| glucocorticoid receptor [Homo sapiens] | 4 | 0 | 0 | 4 |
| retinoic acid nuclear receptor alpha variant 1 | 4 | 0 | 0 | 4 |
| estrogen-related nuclear receptor alpha | 5 | 0 | 0 | 5 |
| estrogen nuclear receptor alpha | 4 | 0 | 0 | 4 |
| cytochrome P450 2D6 | 1 | 0 | 0 | 1 |
| glucocerebrosidase | 2 | 0 | 0 | 2 |
| peroxisome proliferator-activated receptor delta | 2 | 0 | 0 | 2 |
| Rac1 protein | 0 | 0 | 1 | 1 |
| IDH1 | 2 | 0 | 0 | 2 |
| cell division cycle 42 (GTP binding protein, 25kDa), partial | 0 | 0 | 1 | 1 |
| Bloom syndrome protein isoform 1 | 2 | 0 | 0 | 2 |
| 15-hydroxyprostaglandin dehydrogenase [NAD(+)] isoform 1 | 2 | 0 | 0 | 2 |
| DNA polymerase iota isoform a (long) | 2 | 0 | 0 | 2 |
| DNA polymerase kappa isoform 1 | 1 | 0 | 0 | 1 |
| muscarinic acetylcholine receptor M1 | 2 | 0 | 0 | 2 |
| lethal factor (plasmid) | 2 | 0 | 0 | 2 |
| Prostaglandin-H2 D-isomerase | 0 | 1 | 0 | 1 |
| ATP-binding cassette sub-family C member 3 | 0 | 2 | 0 | 2 |
| Multidrug resistance-associated protein 4 | 0 | 2 | 0 | 2 |
| Solute carrier family 22 member 6 | 0 | 1 | 0 | 1 |
| Prostaglandin G/H synthase 1 | 0 | 1 | 0 | 1 |
| Prostaglandin G/H synthase 2 | 0 | 1 | 0 | 1 |
| Bile salt export pump | 0 | 2 | 0 | 2 |
| Epidermal growth factor receptor | 0 | 1 | 0 | 1 |
| Carbonic anhydrase 1 | 0 | 2 | 0 | 2 |
| Carbonic anhydrase 2 | 0 | 2 | 0 | 2 |
| Fatty acid-binding protein, liver | 0 | 1 | 0 | 1 |
| Integrin beta-3 | 1 | 1 | 0 | 2 |
| Myeloperoxidase | 0 | 1 | 0 | 1 |
| Prostaglandin G/H synthase 1 | 0 | 1 | 0 | 1 |
| Seed linoleate 13S-lipoxygenase-1 | 0 | 1 | 0 | 1 |
| Integrin alpha-IIb | 1 | 1 | 0 | 2 |
| Glutathione hydrolase 1 proenzyme | 0 | 1 | 0 | 1 |
| Prostaglandin G/H synthase 1 | 0 | 3 | 0 | 3 |
| Adenosine receptor A1 | 0 | 1 | 0 | 1 |
| Adenosine receptor A2a | 0 | 1 | 0 | 1 |
| Substance-P receptor | 0 | 1 | 0 | 1 |
| Prostaglandin G/H synthase 2 | 0 | 2 | 0 | 2 |
| Urotensin-2 receptor | 0 | 1 | 0 | 1 |
| 4-aminobutyrate aminotransferase, mitochondrial | 0 | 1 | 0 | 1 |
| Nuclear receptor ROR-gamma | 2 | 0 | 0 | 2 |
| Ras-related protein Rab-2A | 0 | 0 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit alpha-1 | 1 | 1 | 0 | 2 |
| Prostaglandin G/H synthase 2 | 0 | 1 | 0 | 1 |
| Rho-associated protein kinase 2 | 0 | 1 | 0 | 1 |
| Nicotinate phosphoribosyltransferase | 0 | 1 | 0 | 1 |
| Solute carrier family 22 member 20 | 0 | 1 | 0 | 1 |
| Solute carrier family 22 member 6 | 0 | 1 | 0 | 1 |
| Canalicular multispecific organic anion transporter 1 | 0 | 2 | 0 | 2 |
| Sigma non-opioid intracellular receptor 1 | 0 | 0 | 1 | 1 |
| Sigma non-opioid intracellular receptor 1 | 0 | 0 | 1 | 1 |
| Chain A, Beta-lactamase | 2 | 0 | 0 | 2 |
| acetylcholinesterase | 1 | 0 | 0 | 1 |
| USP1 protein, partial | 1 | 0 | 0 | 1 |
| TDP1 protein | 4 | 0 | 0 | 4 |
| pregnane X nuclear receptor | 3 | 0 | 0 | 3 |
| cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a | 3 | 0 | 0 | 3 |
| thyroid hormone receptor beta isoform a | 2 | 0 | 0 | 2 |
| nuclear factor erythroid 2-related factor 2 isoform 2 | 2 | 0 | 0 | 2 |
| mitogen-activated protein kinase 1 | 2 | 0 | 0 | 2 |
| Vpr | 1 | 0 | 0 | 1 |
| lamin isoform A-delta10 | 1 | 0 | 0 | 1 |
| Bile salt export pump | 0 | 1 | 0 | 1 |
| Albumin | 0 | 0 | 1 | 1 |
| Major prion protein | 0 | 0 | 1 | 1 |
| Cellular tumor antigen p53 | 3 | 0 | 0 | 3 |
| Sodium channel protein type 1 subunit alpha | 0 | 1 | 0 | 1 |
| Sodium channel protein type 2 subunit alpha | 0 | 1 | 0 | 1 |
| Sodium channel protein type 3 subunit alpha | 0 | 1 | 0 | 1 |
| Cytochrome P450 2C9 | 0 | 1 | 0 | 1 |
| UDP-glucuronosyltransferase 2B7 | 0 | 0 | 0 | 1 |
| Cytochrome P450 2B6 | 0 | 0 | 1 | 1 |
| Sodium channel protein type 4 subunit alpha | 0 | 1 | 0 | 2 |
| Cytochrome P450 2J2 | 0 | 1 | 0 | 1 |
| Potassium voltage-gated channel subfamily H member 2 | 0 | 1 | 0 | 1 |
| Sodium channel protein type 9 subunit alpha | 0 | 2 | 0 | 2 |
| Frizzled-8 | 0 | 0 | 1 | 1 |
| P2X purinoceptor 4 | 0 | 1 | 0 | 1 |
| 15-lipoxygenase, partial | 1 | 0 | 0 | 1 |
| ATAD5 protein, partial | 1 | 0 | 0 | 1 |
| Microtubule-associated protein tau | 1 | 0 | 0 | 1 |
| Thrombopoietin | 1 | 0 | 0 | 1 |
| regulator of G-protein signaling 4 | 1 | 0 | 0 | 1 |
| nonstructural protein 1 | 2 | 0 | 0 | 2 |
| Parkin | 1 | 0 | 0 | 1 |
| arylsulfatase A | 1 | 0 | 0 | 1 |
| pyruvate kinase | 1 | 0 | 0 | 1 |
| heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 2 | 0 | 0 | 2 |
| cytochrome P450 2D6 isoform 1 | 1 | 0 | 0 | 1 |
| NPC intracellular cholesterol transporter 1 precursor | 1 | 0 | 0 | 1 |
| peripheral myelin protein 22 isoform 1 | 1 | 0 | 0 | 1 |
| cellular tumor antigen p53 isoform a | 1 | 0 | 0 | 1 |
| cytochrome P450 2C19 precursor | 1 | 0 | 0 | 1 |
| cytochrome P450 2C9 precursor | 1 | 0 | 0 | 1 |
| atrial natriuretic peptide receptor 2 precursor | 1 | 0 | 0 | 1 |
| ras-related protein Rab-9A | 1 | 0 | 0 | 1 |
| nuclear receptor ROR-gamma isoform 1 | 3 | 0 | 0 | 3 |
| survival motor neuron protein isoform d | 1 | 0 | 0 | 1 |
| cytochrome P450 3A4 isoform 1 | 1 | 0 | 0 | 1 |
| pyruvate kinase PKM isoform b | 1 | 0 | 0 | 1 |
| Gamma-aminobutyric acid receptor subunit pi | 1 | 0 | 0 | 1 |
| RAF proto-oncogene serine/threonine-protein kinase | 0 | 1 | 0 | 1 |
| Luciferin 4-monooxygenase | 0 | 1 | 0 | 1 |
| Ornithine decarboxylase | 1 | 0 | 0 | 1 |
| Gamma-aminobutyric acid receptor subunit beta-1 | 1 | 0 | 0 | 1 |
| Gamma-aminobutyric acid receptor subunit delta | 1 | 0 | 0 | 1 |
| Gamma-aminobutyric acid receptor subunit gamma-2 | 1 | 0 | 0 | 1 |
| Amine oxidase [flavin-containing] B | 0 | 1 | 0 | 1 |
| Gamma-aminobutyric acid receptor subunit alpha-5 | 1 | 0 | 0 | 1 |
| Gamma-aminobutyric acid receptor subunit alpha-3 | 1 | 0 | 0 | 1 |
| Gamma-aminobutyric acid receptor subunit gamma-1 | 1 | 0 | 0 | 1 |
| Gamma-aminobutyric acid receptor subunit alpha-2 | 1 | 0 | 0 | 1 |
| Mitogen-activated protein kinase 3 | 0 | 0 | 0 | 1 |
| Gamma-aminobutyric acid receptor subunit alpha-4 | 1 | 0 | 0 | 1 |
| Gamma-aminobutyric acid receptor subunit gamma-3 | 1 | 0 | 0 | 1 |
| Mitogen-activated protein kinase 1 | 0 | 1 | 0 | 1 |
| Gamma-aminobutyric acid receptor subunit alpha-6 | 1 | 0 | 0 | 1 |
| Dual specificity mitogen-activated protein kinase kinase 2 | 0 | 1 | 0 | 1 |
| Histamine H2 receptor | 2 | 0 | 0 | 2 |
| Gamma-aminobutyric acid receptor subunit beta-3 | 1 | 0 | 0 | 1 |
| Gamma-aminobutyric acid receptor subunit beta-2 | 1 | 0 | 0 | 1 |
| Dual specificity mitogen-activated protein kinase kinase 1 | 0 | 1 | 0 | 1 |
| Dual specificity mitogen-activated protein kinase kinase 1 | 0 | 1 | 0 | 1 |
| GABA theta subunit | 1 | 0 | 0 | 1 |
| Ataxin-2 | 2 | 0 | 0 | 2 |
| Gamma-aminobutyric acid receptor subunit epsilon | 1 | 0 | 0 | 1 |
| ATP-dependent phosphofructokinase | 1 | 0 | 0 | 1 |
| pregnane X receptor | 2 | 0 | 0 | 2 |
| GLI family zinc finger 3 | 2 | 0 | 0 | 2 |
| thioredoxin glutathione reductase | 1 | 0 | 0 | 1 |
| hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 1 | 0 | 0 | 1 |
| estrogen receptor 2 (ER beta) | 2 | 0 | 0 | 2 |
| nuclear receptor subfamily 1, group I, member 3 | 2 | 0 | 0 | 2 |
| progesterone receptor | 2 | 0 | 0 | 2 |
| vitamin D (1,25- dihydroxyvitamin D3) receptor | 1 | 0 | 0 | 1 |
| v-jun sarcoma virus 17 oncogene homolog (avian) | 1 | 0 | 0 | 1 |
| vitamin D3 receptor isoform VDRA | 2 | 0 | 0 | 2 |
| thyroid hormone receptor beta isoform 2 | 2 | 0 | 0 | 2 |
| nuclear factor erythroid 2-related factor 2 isoform 1 | 2 | 0 | 0 | 2 |
| Glucocorticoid receptor | 0 | 2 | 1 | 3 |
| Glycine receptor subunit alpha-1 | 0 | 2 | 0 | 2 |
| Glycine receptor subunit beta | 0 | 2 | 0 | 2 |
| Glycine receptor subunit alpha-2 | 0 | 2 | 0 | 2 |
| Glycine receptor subunit alpha-3 | 0 | 2 | 0 | 2 |
| Chain A, Ferritin light chain | 1 | 0 | 0 | 1 |
| glp-1 receptor, partial | 1 | 0 | 0 | 1 |
| phosphopantetheinyl transferase | 1 | 0 | 0 | 1 |
| SMAD family member 2 | 1 | 0 | 0 | 1 |
| SMAD family member 3 | 1 | 0 | 0 | 1 |
| farnesoid X nuclear receptor | 1 | 0 | 0 | 1 |
| aryl hydrocarbon receptor | 1 | 0 | 0 | 1 |
| heat shock protein HSP 90-alpha isoform 2 | 0 | 0 | 0 | 1 |
| Polyunsaturated fatty acid lipoxygenase ALOX15B | 1 | 0 | 0 | 1 |
| Voltage-dependent calcium channel gamma-2 subunit | 1 | 0 | 0 | 1 |
| Cytochrome P450 3A4 | 0 | 1 | 0 | 1 |
| Glutamate receptor 2 | 1 | 0 | 0 | 1 |
| TAR DNA-binding protein 43 | 1 | 0 | 0 | 1 |
| ATPase family AAA domain-containing protein 5 | 1 | 0 | 0 | 1 |
| heat shock protein 90, putative | 0 | 0 | 0 | 1 |
| [prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023] |