Page last updated: 2024-09-27

Acute Lung Injury, Transfusion-Related

A rare but serious transfusion-related reaction in which fluid builds up in the lungs unrelated to excessively high infusion rate and/or volume (TRANSFUSION-ASSOCIATED CIRCULATORY OVERLOAD). Signs of Transfusion-Related Acute Lung Injury include pulmonary secretions; hypotension; fever; DYSPNEA; TACHYPNEA; TACHYCARDIA; and CYANOSIS.

Synonyms(3)

Synonym
Acute Lung Injury, Transfusion-Related
TRALI
Transfusion-Related Acute Lung Injury

Research Excerpts

Treatment

ExcerptReference
"Methods Antibody-mediated TRALI was experimentally induced in mice by lipopolysaccharide priming followed by the administration of an anti-MHC I mAb."( de la Salle, H; El Mdawar, MB; Gachet, C; Hechler, B; Heim, V; Magnenat, S; MaƮtre, B, 2016)

Research

Studies (13)

TimeframeStudies, This Condition (%)All Conditions %
pre-19900 (0.00)23.3326
1990's0 (0.00)12.5806
2000's0 (0.00)18.1394
2010's2 (15.38)28.8240
2020's11 (84.62)9.53
DrugIndicatedRelationship StrengthStudiesTrials
aspirin0low10
hydroxychloroquine0low10
ticlopidine0low10
tyrosine0low10
clopidogrel0low10
tirofiban0low10
fibrinogen0low10
lopinavir0low10
ritonavir0low10
fibrin0low20
vu00997040low10
dasatinib0low10
sphingosine0low10
sphingosine 1-phosphate0low10
natriuretic peptide, brain0medium11
cyclosporine0low10

Protein Targets (842)

ProteinPotency MeasurementsInhibition MeasurementsActivation MeasurementsDrugs
Chain A, MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASE2002
Chain A, TYROSYL-DNA PHOSPHODIESTERASE1001
Chain A, Phospholipase A2 isoform 30011
Chain A, HADH2 protein1001
Chain B, HADH2 protein1001
Chain A, 2-oxoglutarate Oxygenase1001
GTP-binding protein (rab7)0011
ras protein, partial0011
interleukin 81001
thioredoxin reductase1001
GLS protein3003
AR protein5005
aldehyde dehydrogenase 1 family, member A14004
thyroid stimulating hormone receptor1001
hypothetical protein, conserved1001
cytochrome P450 family 3 subfamily A polypeptide 46006
EWS/FLI fusion protein7007
glucocorticoid receptor [Homo sapiens]5005
retinoic acid nuclear receptor alpha variant 14004
estrogen-related nuclear receptor alpha4004
estrogen nuclear receptor alpha6006
cytochrome P450 2D65005
glucocerebrosidase2002
peroxisome proliferator-activated receptor delta4004
Rac1 protein0011
IDH13003
cell division cycle 42 (GTP binding protein, 25kDa), partial0011
euchromatic histone-lysine N-methyltransferase 22002
Bloom syndrome protein isoform 12002
15-hydroxyprostaglandin dehydrogenase [NAD(+)] isoform 11001
DNA polymerase iota isoform a (long)4004
DNA polymerase kappa isoform 13003
muscarinic acetylcholine receptor M11001
lethal factor (plasmid)1001
Prostaglandin-H2 D-isomerase0101
ATP-binding cassette sub-family C member 30404
Multidrug resistance-associated protein 40404
Solute carrier family 22 member 60101
Prostaglandin G/H synthase 1 0101
Prostaglandin G/H synthase 2 0101
Bile salt export pump0505
Epidermal growth factor receptor0213
Carbonic anhydrase 10203
Carbonic anhydrase 20203
Fatty acid-binding protein, liver0101
Integrin beta-30214
Myeloperoxidase0101
Prostaglandin G/H synthase 10101
Seed linoleate 13S-lipoxygenase-10101
Integrin alpha-IIb0214
Glutathione hydrolase 1 proenzyme0101
Prostaglandin G/H synthase 10202
Adenosine receptor A10102
Adenosine receptor A2a0102
Substance-P receptor0101
Prostaglandin G/H synthase 20213
Urotensin-2 receptor0101
4-aminobutyrate aminotransferase, mitochondrial0101
Nuclear receptor ROR-gamma1001
Ras-related protein Rab-2A0011
Gamma-aminobutyric acid receptor subunit alpha-11102
Prostaglandin G/H synthase 20101
Rho-associated protein kinase 20101
Nicotinate phosphoribosyltransferase0101
Solute carrier family 22 member 200101
Solute carrier family 22 member 60101
Canalicular multispecific organic anion transporter 10404
Sigma non-opioid intracellular receptor 10314
Sigma non-opioid intracellular receptor 10011
nonstructural protein 11001
chromobox protein homolog 12002
parathyroid hormone/parathyroid hormone-related peptide receptor precursor2002
geminin4004
Cytochrome P450 2C80202
Cytochrome P450 2B60404
Liver carboxylesterase 10001
Sodium-dependent serotonin transporter0314
Cytochrome P450 2C190505
Rap guanine nucleotide exchange factor 41001
P2Y purinoceptor 120101
Leukotriene C4 synthase0011
acetylcholinesterase2002
RAR-related orphan receptor gamma2002
Fumarate hydratase3003
GALC protein1001
PPM1D protein1001
TDP1 protein6006
GLI family zinc finger 33003
Smad32002
caspase 7, apoptosis-related cysteine protease1001
estrogen receptor 2 (ER beta)3003
nuclear receptor subfamily 1, group I, member 33003
progesterone receptor4004
retinoid X nuclear receptor alpha3003
farnesoid X nuclear receptor3003
pregnane X nuclear receptor4004
polyprotein3003
67.9K protein3003
peroxisome proliferator activated receptor gamma3003
vitamin D (1,25- dihydroxyvitamin D3) receptor1001
caspase-31001
aryl hydrocarbon receptor2002
cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a3003
thyroid stimulating hormone receptor2002
nuclear receptor subfamily 1, group I, member 22002
Histone H2A.x1001
Spike glycoprotein0033
Replicase polyprotein 1ab0033
thyroid hormone receptor beta isoform 24004
huntingtin isoform 21001
serine/threonine-protein kinase mTOR isoform 11001
tyrosine-protein kinase Yes1001
nuclear factor erythroid 2-related factor 2 isoform 13003
peripheral myelin protein 222002
Bone morphogenetic protein receptor type-1B0011
Membrane-associated progesterone receptor component 10011
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform0112
Serine/threonine-protein kinase PLK40011
Serine/threonine-protein kinase 250011
ATP-dependent RNA helicase DDX3X0011
Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta0011
Pyridoxal kinase0011
Citron Rho-interacting kinase0011
Serine/threonine-protein kinase RIO30011
Dual specificity mitogen-activated protein kinase kinase 70011
Serine/threonine-protein kinase Chk10011
Inhibitor of nuclear factor kappa-B kinase subunit beta0112
Peripheral plasma membrane protein CASK0011
Aurora kinase A0112
Cyclin-G-associated kinase0011
Serine/threonine-protein kinase DCLK10011
Inhibitor of nuclear factor kappa-B kinase subunit alpha0112
Muscle, skeletal receptor tyrosine-protein kinase0011
Ephrin type-B receptor 60011
Peroxisomal acyl-coenzyme A oxidase 30011
Mitogen-activated protein kinase 130112
Transmembrane protease serine 20033
3-phosphoinositide-dependent protein kinase 10011
Mitogen-activated protein kinase kinase kinase 130011
Death-associated protein kinase 30011
Mitogen-activated protein kinase kinase kinase 70011
Receptor-interacting serine/threonine-protein kinase 20213
Mitotic checkpoint serine/threonine-protein kinase BUB10011
NUAK family SNF1-like kinase 10011
Dynamin-like 120 kDa protein, mitochondrial0011
Phosphatidylinositol 4-phosphate 5-kinase type-1 gamma0011
Tyrosine-protein kinase JAK20011
Voltage-dependent L-type calcium channel subunit alpha-1F0101
Eukaryotic translation initiation factor 5B0011
Rho-associated protein kinase 20011
Serine/threonine-protein kinase ULK10011
Serine/threonine-protein kinase/endoribonuclease IRE10011
Ribosomal protein S6 kinase alpha-50011
U5 small nuclear ribonucleoprotein 200 kDa helicase0011
Ribosomal protein S6 kinase alpha-40011
Serine/threonine-protein kinase 160011
Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit gamma0011
Serine/threonine-protein kinase PAK 30011
Cyclin-dependent kinase-like 50011
Voltage-dependent calcium channel gamma-2 subunit2002
Serine/threonine-protein kinase 17B0011
Serine/threonine-protein kinase 100011
Serine/threonine-protein kinase D30011
Cyclin-dependent kinase 140011
Structural maintenance of chromosomes protein 20011
Mitogen-activated protein kinase kinase kinase 60011
Serine/threonine-protein kinase OSR10011
Mitogen-activated protein kinase kinase kinase kinase 40011
Serine/threonine-protein kinase LATS10011
Serine/threonine-protein kinase PAK 40011
Serine/threonine-protein kinase Chk20011
Tyrosine-protein kinase ABL10326
Tyrosine-protein kinase ABL10101
Proto-oncogene tyrosine-protein kinase Src0112
Interferon beta5005
Transthyretin0011
RAF proto-oncogene serine/threonine-protein kinase0112
Receptor tyrosine-protein kinase erbB-20112
High affinity nerve growth factor receptor0011
Cellular tumor antigen p533003
Guanine nucleotide-binding protein G(i) subunit alpha-20011
ADP/ATP translocase 20011
Cytochrome P450 1A20203
Neuronal proto-oncogene tyrosine-protein kinase Src 0001
Protein kinase C beta type0011
Insulin receptor0112
Tyrosine-protein kinase Lck0314
Proto-oncogene tyrosine-protein kinase LCK 0202
Tyrosine-protein kinase Fyn0213
Cyclin-dependent kinase 10011
Glycogen phosphorylase, liver form0011
Tyrosine-protein kinase Fes/Fps0011
Macrophage colony-stimulating factor 1 receptor0213
Procathepsin L0033
Adenine phosphoribosyltransferase0011
Tyrosine-protein kinase Yes0112
Tyrosine-protein kinase Lyn0112
Proto-oncogene tyrosine-protein kinase receptor Ret0112
Insulin-like growth factor 1 receptor0112
Signal recognition particle receptor subunit alpha0011
Cytochrome c1, heme protein, mitochondrial0011
Hepatocyte growth factor receptor0011
Tyrosine-protein kinase HCK0213
Proto-oncogene tyrosine-protein kinase ROS0011
Platelet-derived growth factor receptor beta0213
Tyrosine-protein kinase Fgr0011
Quinolone resistance protein NorA0101
Wee1-like protein kinase 20011
Uncharacterized serine/threonine-protein kinase SBK30011
Replicase polyprotein 1a0033
Replicase polyprotein 1ab0033
Replicase polyprotein 1ab0235
Replicase polyprotein 1ab0437
Serine/threonine-protein kinase A-Raf0011
Cytochrome P450 2D60304
Mast/stem cell growth factor receptor Kit0112
Glycogen phosphorylase, brain form0011
Breakpoint cluster region protein0225
Serine/threonine-protein kinase pim-10011
Fibroblast growth factor receptor 10112
Cytochrome P450 2A60101
Cytochrome P450 2C9 0304
Myosin light chain kinase, smooth muscle0011
Cyclin-dependent kinase 40011
ADP/ATP translocase 30011
Inosine-5'-monophosphate dehydrogenase 20011
Angiotensin-converting enzyme 0101
Proto-oncogene tyrosine-protein kinase Src0314
cAMP-dependent protein kinase type II-alpha regulatory subunit0011
Insulin receptor-related protein0011
Serine/threonine-protein kinase B-raf0011
Potassium voltage-gated channel subfamily E member 10101
Phosphorylase b kinase gamma catalytic chain, liver/testis isoform0011
Ribosyldihydronicotinamide dehydrogenase [quinone]0011
Platelet-derived growth factor receptor alpha0213
Tyrosine-protein kinase Blk0101
Tyrosine-protein kinase Fer0011
Protein kinase C alpha type0112
cAMP-dependent protein kinase catalytic subunit alpha0011
Vascular endothelial growth factor receptor 1 0011
General transcription and DNA repair factor IIH helicase subunit XPD0011
Glutamate receptor 22002
Interferon-induced, double-stranded RNA-activated protein kinase0011
Casein kinase II subunit alpha'0011
Ras-related protein Rab-6A0011
Serine/threonine-protein kinase MAK0011
Cyclin-dependent kinase 11B0011
Ephrin type-A receptor 10011
Fibroblast growth factor receptor 20011
Receptor tyrosine-protein kinase erbB-30011
Multifunctional protein ADE20011
Fibroblast growth factor receptor 40011
Fibroblast growth factor receptor 30011
cAMP-dependent protein kinase catalytic subunit gamma0011
cAMP-dependent protein kinase catalytic subunit beta0011
Ferrochelatase, mitochondrial0011
Ribosomal protein S6 kinase beta-10011
Tyrosine-protein kinase JAK10011
Protein kinase C eta type0011
Cyclin-dependent kinase 20112
Beta-adrenergic receptor kinase 10011
Probable ATP-dependent RNA helicase DDX60011
Activin receptor type-2A0011
Mitogen-activated protein kinase 3 0011
MAP/microtubule affinity-regulating kinase 30011
Deoxycytidine kinase0011
Mitogen-activated protein kinase 10011
Ephrin type-A receptor 20112
Ephrin type-A receptor 30011
Ephrin type-A receptor 80011
Ephrin type-B receptor 20112
Leukocyte tyrosine kinase receptor0011
Non-receptor tyrosine-protein kinase TYK20011
UMP-CMP kinase 0011
Phosphatidylethanolamine-binding protein 10011
Wee1-like protein kinase0011
Heme oxygenase 20011
Tyrosine-protein kinase receptor UFO0011
Mitogen-activated protein kinase 40011
S-adenosylmethionine synthase isoform type-20011
DnaJ homolog subfamily A member 10011
RAC-alpha serine/threonine-protein kinase0112
RAC-beta serine/threonine-protein kinase0112
G protein-coupled receptor kinase 40011
Dual specificity protein kinase TTK0011
DNA replication licensing factor MCM40011
Tyrosine-protein kinase receptor Tie-10011
Vascular endothelial growth factor receptor 30011
Vascular endothelial growth factor receptor 20112
Dual specificity mitogen-activated protein kinase kinase 20112
Receptor-type tyrosine-protein kinase FLT30112
Bone morphogenetic protein receptor type-1A0011
Activin receptor type-1B0011
TGF-beta receptor type-10011
Serine/threonine-protein kinase receptor R30011
TGF-beta receptor type-20011
Electron transfer flavoprotein subunit beta0011
Tyrosine-protein kinase CSK0112
Glycine--tRNA ligase0011
Protein kinase C iota type0011
Exosome RNA helicase MTR40011
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform0112
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform0112
Serine/threonine-protein kinase mTOR0112
Megakaryocyte-associated tyrosine-protein kinase0011
Tyrosine-protein kinase Tec0112
Tyrosine-protein kinase TXK0112
Tyrosine-protein kinase ABL20011
Tyrosine-protein kinase FRK0011
G protein-coupled receptor kinase 60011
Tyrosine-protein kinase ZAP-700011
Tyrosine-protein kinase SYK0112
26S proteasome regulatory subunit 6B0011
Mitogen-activated protein kinase 80011
Mitogen-activated protein kinase 90011
Dual specificity mitogen-activated protein kinase kinase 40011
Dual specificity mitogen-activated protein kinase kinase 30011
Casein kinase I isoform alpha0112
Casein kinase I isoform delta0011
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform 0112
MAP kinase-activated protein kinase 20112
Cyclin-dependent kinase 80011
Elongation factor Tu, mitochondrial0011
Choline-phosphate cytidylyltransferase A0011
Cysteine--tRNA ligase, cytoplasmic0011
Casein kinase I isoform epsilon0011
Very long-chain specific acyl-CoA dehydrogenase, mitochondrial0011
Dual specificity protein kinase CLK10011
Dual specificity protein kinase CLK20011
Dual specificity protein kinase CLK30011
Glycogen synthase kinase-3 alpha0011
Glycogen synthase kinase-3 beta0011
Cyclin-dependent kinase 70011
Cyclin-dependent kinase 90011
Ras-related protein Rab-27A0011
Tyrosine-protein kinase Blk0112
Interleukin-1 receptor-associated kinase 10011
Potassium voltage-gated channel subfamily KQT member 10101
Ribosomal protein S6 kinase alpha-30112
Cytoplasmic tyrosine-protein kinase BMX0011
cAMP-dependent protein kinase catalytic subunit PRKX0011
Serine/threonine-protein kinase Nek20011
Serine/threonine-protein kinase Nek30011
Serine/threonine-protein kinase Nek40011
Tyrosine-protein kinase JAK30011
Dual specificity mitogen-activated protein kinase kinase 60011
Serine/threonine-protein kinase PLK10011
Death-associated protein kinase 10011
LIM domain kinase 10112
LIM domain kinase 20112
Mitogen-activated protein kinase 120112
Mitogen-activated protein kinase 100011
Tyrosine--tRNA ligase, cytoplasmic0011
5'-AMP-activated protein kinase subunit gamma-10011
5'-AMP-activated protein kinase catalytic subunit alpha-20011
Ephrin type-B receptor 30011
Ephrin type-A receptor 50011
Ephrin type-B receptor 40112
Ephrin type-B receptor 10011
Ephrin type-A receptor 40011
Adenylate kinase 2, mitochondrial0011
Adenosine kinase0011
Hormonally up-regulated neu tumor-associated kinase0011
Serine/threonine-protein kinase SIK10213
Receptor-interacting serine/threonine-protein kinase 40011
Spike glycoprotein1034
Ras-related protein Rab-100011
Cell division control protein 2 homolog0011
Actin-related protein 30011
Actin-related protein 20011
Calcium-dependent protein kinase 10011
GTP-binding nuclear protein Ran0011
Tubulin alpha-1A chain0011
Casein kinase II subunit alpha0011
Phosphatidylinositol 5-phosphate 4-kinase type-2 beta0011
SRSF protein kinase 20011
Casein kinase I isoform gamma-20011
DNA-dependent protein kinase catalytic subunit0101
Mitogen-activated protein kinase kinase kinase 90011
Serine/threonine-protein kinase PknB0011
Cyclin-dependent kinase 30011
Cyclin-dependent kinase-like 10011
Cyclin-dependent kinase 60011
Cyclin-dependent-like kinase 5 0011
Cyclin-dependent kinase 160011
Cyclin-dependent kinase 170011
Myelin transcription factor 10101
Voltage-dependent L-type calcium channel subunit alpha-1D 0101
ATP-dependent 6-phosphofructokinase, platelet type0011
Protein kinase C epsilon type0011
Dual specificity mitogen-activated protein kinase kinase 10112
Angiopoietin-1 receptor0011
Mitogen-activated protein kinase kinase kinase 100011
DNA topoisomerase 2-beta0011
Protein kinase C theta type0011
Activin receptor type-10011
Macrophage-stimulating protein receptor0011
Focal adhesion kinase 10112
Protein kinase C zeta type0112
Protein kinase C delta type0112
Tyrosine-protein kinase BTK0213
Tyrosine-protein kinase receptor TYRO30011
Cyclin-dependent kinase 180011
Activated CDC42 kinase 10112
Epithelial discoidin domain-containing receptor 10314
Tyrosine-protein kinase ITK/TSK0112
Myotonin-protein kinase0011
Potassium voltage-gated channel subfamily H member 20303
Mitogen-activated protein kinase kinase kinase kinase 20011
Mitogen-activated protein kinase kinase kinase 120011
Tyrosine-protein kinase Mer0011
Serine/threonine-protein kinase 40011
5'-AMP-activated protein kinase catalytic subunit alpha-10011
Serine/threonine-protein kinase PAK 10011
Dual specificity mitogen-activated protein kinase kinase 50011
Mitogen-activated protein kinase 70011
Serine/threonine-protein kinase PAK 20011
Serine/threonine-protein kinase 30011
Mitogen-activated protein kinase kinase kinase 10011
cGMP-dependent protein kinase 20011
Integrin-linked protein kinase0011
Rho-associated protein kinase 10011
Non-receptor tyrosine-protein kinase TNK10011
Serine/threonine-protein kinase PRP4 homolog0011
Receptor-interacting serine/threonine-protein kinase 10011
Calcium/calmodulin-dependent protein kinase type II subunit beta0011
Calcium/calmodulin-dependent protein kinase type II subunit gamma0011
Calcium/calmodulin-dependent protein kinase type II subunit delta0011
Dual specificity tyrosine-phosphorylation-regulated kinase 1A0011
Voltage-dependent L-type calcium channel subunit alpha-1S0101
Activin receptor type-2B0011
Bone morphogenetic protein receptor type-20011
Protein-tyrosine kinase 60112
Voltage-dependent L-type calcium channel subunit alpha-1C0101
cGMP-dependent protein kinase 1 0011
Cyclin-dependent kinase 130011
Calcium/calmodulin-dependent protein kinase type 10011
Inhibitor of nuclear factor kappa-B kinase subunit epsilon0011
Protein-tyrosine kinase 2-beta0011
Sodium channel protein type 5 subunit alpha0101
Maternal embryonic leucine zipper kinase0011
Structural maintenance of chromosomes protein 1A0011
Chromodomain-helicase-DNA-binding protein 40011
Peroxisomal acyl-coenzyme A oxidase 10011
Serine/threonine-protein kinase D10011
Serine/threonine-protein kinase 380011
Receptor tyrosine-protein kinase erbB-40011
Ribosomal protein S6 kinase alpha-20011
Ephrin type-A receptor 70011
Delta(24)-sterol reductase0011
Ribosomal protein S6 kinase alpha-10112
Dual specificity testis-specific protein kinase 10011
Myosin light chain kinase, smooth muscle0011
Mitogen-activated protein kinase 110112
Serine/threonine-protein kinase STK110011
Rhodopsin kinase GRK10011
NT-3 growth factor receptor0011
Serine/threonine-protein kinase N10011
Serine/threonine-protein kinase N20011
Mitogen-activated protein kinase 140123
Calcium/calmodulin-dependent protein kinase type IV0011
Mitogen-activated protein kinase kinase kinase 110011
BDNF/NT-3 growth factors receptor0011
Mitogen-activated protein kinase 60011
Phosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoform0011
Discoidin domain-containing receptor 20213
AP2-associated protein kinase 10011
Myosin light chain kinase 30011
Uncharacterized aarF domain-containing protein kinase 50011
Serine/threonine-protein kinase SBK10011
Mitogen-activated protein kinase kinase kinase 190011
Putative heat shock protein HSP 90-beta 20011
Serine/threonine-protein kinase TNNI3K0011
Leucine-rich repeat serine/threonine-protein kinase 20011
Serine/threonine-protein kinase MRCK alpha0011
Serine/threonine-protein kinase MRCK gamma0011
Acyl-CoA dehydrogenase family member 100011
Serine/threonine-protein kinase Nek50011
Serine/threonine-protein kinase N30011
Breakpoint cluster region protein0101
Serine/threonine-protein kinase ULK30011
Dual serine/threonine and tyrosine protein kinase0011
Mitogen-activated protein kinase kinase kinase 150011
Uncharacterized protein FLJ452520011
Acyl-CoA dehydrogenase family member 110011
Serine/threonine-protein kinase/endoribonuclease IRE20011
Serine/threonine-protein kinase MARK20011
Serine/threonine-protein kinase TAO10011
STE20-related kinase adapter protein alpha0011
Myosin-140011
AarF domain-containing protein kinase 10011
Serine/threonine-protein kinase tousled-like 20011
Serine/threonine-protein kinase 32C0011
Serine/threonine-protein kinase pim-30011
ATP-dependent RNA helicase DDX420011
Serine/threonine-protein kinase VRK20011
Myosin light chain kinase family member 40011
Homeodomain-interacting protein kinase 10011
Calcium/calmodulin-dependent protein kinase type 1D0011
Mitogen-activated protein kinase kinase kinase kinase 30011
Cyclin-dependent kinase-like 30011
MAP kinase-activated protein kinase 50011
Serine/threonine-protein kinase BRSK20011
Serine/threonine-protein kinase NIM10011
Eukaryotic peptide chain release factor GTP-binding subunit ERF3B0011
Serine/threonine-protein kinase ULK20011
Misshapen-like kinase 10011
Serine/threonine-protein kinase DCLK20011
Calcium/calmodulin-dependent protein kinase kinase 10011
Casein kinase I isoform alpha-like0011
Homeodomain-interacting protein kinase 40011
Myosin-IIIa0011
Ankyrin repeat and protein kinase domain-containing protein 10011
Serine/threonine-protein kinase Nek110011
Atypical kinase COQ8A, mitochondrial0011
Phosphatidylinositol 5-phosphate 4-kinase type-2 gamma0011
Mitogen-activated protein kinase 150011
Serine/threonine-protein kinase Nek90011
Serine/threonine-protein kinase BRSK10011
Serine/threonine-protein kinase 350011
Serine/threonine-protein kinase Nek70011
Rhodopsin kinase GRK70011
Serine/threonine-protein kinase 32A0011
Myosin-IIIb0011
ATP-dependent RNA helicase DDX10011
Dual specificity tyrosine-phosphorylation-regulated kinase 20011
Cyclin-dependent kinase-like 20011
Mitogen-activated protein kinase kinase kinase kinase 10011
Serine/threonine-protein kinase Sgk30011
Atypical kinase COQ8B, mitochondrial0011
Aurora kinase B0112
MAP/microtubule affinity-regulating kinase 40011
Calcium/calmodulin-dependent protein kinase type 1G0011
Serine/threonine-protein kinase Nek10011
Cyclin-dependent kinase 150011
ATPase family AAA domain-containing protein 53003
PAS domain-containing serine/threonine-protein kinase0011
Calcium/calmodulin-dependent protein kinase kinase 20011
EKC/KEOPS complex subunit TP53RK0011
Dual specificity testis-specific protein kinase 20011
SRSF protein kinase 10011
Protein cereblon0012
Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase0213
Mitogen-activated protein kinase kinase kinase 50011
Ataxin-23003
Phosphatidylinositol 4-phosphate 5-kinase type-1 alpha0011
Mitogen-activated protein kinase kinase kinase 30011
Eukaryotic translation initiation factor 2-alpha kinase 10011
Serine/threonine-protein kinase RIO10011
MAP kinase-interacting serine/threonine-protein kinase 10011
Serine/threonine-protein kinase RIO20011
Cyclin-dependent kinase 190011
Transient receptor potential cation channel subfamily M member 60011
Testis-specific serine/threonine-protein kinase 10011
Angiotensin-converting enzyme 2 0033
Serine/threonine-protein kinase 330011
Nucleolar GTP-binding protein 10011
Serine/threonine-protein kinase D20011
Serine/threonine-protein kinase DCLK30011
NUAK family SNF1-like kinase 20011
RNA cytidine acetyltransferase0011
Serine/threonine-protein kinase SIK20112
Myosin light chain kinase 2, skeletal/cardiac muscle0011
STE20-like serine/threonine-protein kinase 0011
Serine/threonine-protein kinase TAO30011
Homeodomain-interacting protein kinase 20011
Tyrosine-protein kinase Srms0011
Homeodomain-interacting protein kinase 30011
Serine/threonine-protein kinase PLK30011
dCTP pyrophosphatase 10011
Dual specificity protein kinase CLK40011
MAP kinase-interacting serine/threonine-protein kinase 20011
Serine/threonine-protein kinase Nek60011
Casein kinase I isoform gamma-10011
Serine/threonine-protein kinase PAK 60011
SNF-related serine/threonine-protein kinase0011
Serine/threonine-protein kinase LATS20011
Serine/threonine-protein kinase 360011
Phenylalanine--tRNA ligase beta subunit0011
Isoleucine--tRNA ligase, mitochondrial0011
BMP-2-inducible protein kinase0011
Obg-like ATPase 10011
Midasin0011
Interleukin-1 receptor-associated kinase 40011
Serine/threonine-protein kinase 32B0011
Mitogen-activated protein kinase kinase kinase 200011
Cyclin-dependent kinase 120011
Serine/threonine-protein kinase PLK20011
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 130011
Serine/threonine-protein kinase MARK10011
Serine/threonine-protein kinase pim-20011
Serine/threonine-protein kinase PAK 50011
Serine/threonine-protein kinase 260011
eIF-2-alpha kinase GCN20011
Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial0011
Serine/threonine-protein kinase NLK0011
Phosphatidylinositol 4-kinase beta0011
Serine/threonine-protein kinase 17A0011
STE20/SPS1-related proline-alanine-rich protein kinase0011
Ephrin type-A receptor 60011
5'-AMP-activated protein kinase subunit gamma-20011
Serine/threonine-protein kinase TBK10011
Septin-90011
Death-associated protein kinase 20011
Potassium voltage-gated channel subfamily D member 30101
Ribosomal protein S6 kinase alpha-60011
TRAF2 and NCK-interacting protein kinase0011
Serine/threonine-protein kinase tousled-like 10011
Serine/threonine-protein kinase TAO20011
Long-chain-fatty-acid--CoA ligase 50011
ALK tyrosine kinase receptor0011
Broad substrate specificity ATP-binding cassette transporter ABCG20303
SRSF protein kinase 30011
Serine/threonine-protein kinase ICK0011
Cyclin-dependent kinase 11A0011
Aurora kinase C0011
Calcium/calmodulin-dependent protein kinase type II subunit alpha0011
RAC-gamma serine/threonine-protein kinase0112
Serine/threonine-protein kinase 38-like0011
Microtubule-associated serine/threonine-protein kinase 10011
Serine/threonine-protein kinase SIK30112
Mitogen-activated protein kinase kinase kinase 20011
Thyroid hormone receptor-associated protein 30011
Dual specificity tyrosine-phosphorylation-regulated kinase 1B0011
Mitogen-activated protein kinase kinase kinase kinase 50011
Receptor-interacting serine/threonine-protein kinase 30011
Serine/threonine-protein kinase MRCK beta0011
Interleukin-1 receptor-associated kinase 30011
Serine/threonine-protein kinase 240011
NF-kappa-B essential modulator0101
Casein kinase I isoform gamma-30011
Mitogen-activated protein kinase kinase kinase 40011
Genome polyprotein 0101
lamin isoform A-delta104004
Muscarinic acetylcholine receptor M20202
Muscarinic acetylcholine receptor M40101
Muscarinic acetylcholine receptor M50101
Alpha-2A adrenergic receptor0303
Muscarinic acetylcholine receptor M10101
Alpha-2B adrenergic receptor0303
Alpha-2C adrenergic receptor0303
Muscarinic acetylcholine receptor M30101
Alpha-1D adrenergic receptor0202
Sigma intracellular receptor 20101
Cyclic GMP-AMP synthase0101
Toll-like receptor 90101
Toll-like receptor 70101
Chain A, protease0101
Chain B, protease0101
Chain A, protease0011
Chain B, protease0011
Chain A, protease0011
Chain B, protease0011
Chain A, protease0011
Chain B, protease0011
Chain A, protease0011
Chain B, protease0011
Chain A, protease0011
Chain B, protease0011
Chain A, Protease0101
Chain B, Protease0101
Chain A, Protease0101
Chain B, Protease0101
Chain A, Protease0101
Chain B, Protease0101
Chain A, PROTEASE RETROPEPSIN0101
Chain B, PROTEASE RETROPEPSIN0101
Chain A, Protease Retropepsin0101
Chain B, Protease Retropepsin0101
Chain A, Protease Retropepsin0101
Chain B, Protease Retropepsin0101
SMAD family member 22002
USP1 protein, partial2002
SMAD family member 32002
G4004
potassium voltage-gated channel subfamily H member 2 isoform d3003
nuclear receptor ROR-gamma isoform 12002
HLA class I histocompatibility antigen, B alpha chain 4004
Albumin0004
Gag-Pol polyprotein0202
Gag-Pol polyprotein0202
Gag-Pol polyprotein0202
ATP-dependent translocase ABCB10202
Cytochrome P450 3A40305
Gag-Pol polyprotein0202
Alpha-1B adrenergic receptor0202
Alpha-1D adrenergic receptor0202
Gag-Pol polyprotein0202
Alpha-1A adrenergic receptor0202
Protease 0327
CAAX prenyl protease 1 homolog0101
Plasmepsin V 0202
Inositol hexakisphosphate kinase 14004
Protease 0437
cytochrome P450 2C9, partial4004
Atrial natriuretic peptide receptor 10101
Chain A, HIV-1 PROTEASE0101
Chain B, HIV-1 PROTEASE0101
Chain A, POL polyprotein0101
Chain B, POL polyprotein0101
Chain A, POL polyprotein0101
Chain B, POL polyprotein0101
Chain A, Beta-lactamase2002
Chain A, Ferritin light chain4004
Chain A, Cruzipain2002
Chain A, Endothiapepsin0101
Chain A, Endothiapepsin0101
Luciferase3003
Microtubule-associated protein tau3003
alpha-galactosidase2002
activating transcription factor 61001
vitamin D3 receptor isoform VDRA2002
mitogen-activated protein kinase 12002
histone acetyltransferase KAT2A isoform 11001
neuropeptide S receptor isoform A2002
Solute carrier family 22 member 20101
Solute carrier family 22 member 1 0101
Nuclear receptor subfamily 1 group I member 20011
Solute carrier family 22 member 30101
Solute carrier organic anion transporter family member 2B1 0202
Gag-Pol polyprotein0101
ATP-dependent translocase ABCB10101
Cytochrome P450 3A50101
ATP-dependent translocase ABCB10101
Substance-K receptor0202
UDP-glucuronosyltransferase 1A1 0101
Thromboxane-A synthase 0101
Mu-type opioid receptor0202
Vasopressin V1a receptor0202
Kappa-type opioid receptor0202
Thromboxane-A synthase0001
Sodium/bile acid cotransporter0101
Multidrug and toxin extrusion protein 20101
Multidrug and toxin extrusion protein 10101
Solute carrier organic anion transporter family member 1B30202
Solute carrier organic anion transporter family member 1B10202
acid sphingomyelinase1001
endonuclease IV1001
phosphopantetheinyl transferase1001
ATAD5 protein, partial2002
apical membrane antigen 1, AMA11001
thyroid hormone receptor beta isoform a1001
C-X-C chemokine receptor type 5 isoform 10101
DNA polymerase beta1001
ubiquitin-conjugating enzyme E2 N0101
C-C chemokine receptor type 60101
apelin receptor0101
DNA polymerase eta isoform 11001
bcl-2-related protein A10101
streptokinase A precursor0011
Endoglycoceramidase II 0001
Protein kinase C alpha type0101
Estrogen receptor0011
Protein kinase C delta type0101
Protein kinase C epsilon type0101
Protein kinase C zeta type0101
cAMP-dependent protein kinase catalytic subunit alpha 0101
Protein kinase C gamma type0101
Protein kinase C beta type0101
Estrogen receptor beta0011
Protein kinase C eta type0101
Sphingosine kinase 20101
Sphingosine kinase 10101
Protein kinase C theta type0101
Sphingosine 1-phosphate receptor 20112
Sphingosine 1-phosphate receptor 40112
Sphingosine 1-phosphate receptor 10112
Sphingosine 1-phosphate receptor 30112
Sphingosine 1-phosphate receptor 50112
Chain A, JmjC domain-containing histone demethylation protein 3A1001
glp-1 receptor, partial2002
nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105), isoform CRA_a1001
v-jun sarcoma virus 17 oncogene homolog (avian)1001
cytochrome P450 2D6 isoform 11001
cytochrome P450 2C19 precursor1001
heat shock protein beta-11001
ubiquitin carboxyl-terminal hydrolase 2 isoform a1001
cytochrome P450 3A4 isoform 11001
Gamma-aminobutyric acid receptor subunit pi1001
Bile salt export pump0101
Gamma-aminobutyric acid receptor subunit beta-11001
Gamma-aminobutyric acid receptor subunit delta1001
Gamma-aminobutyric acid receptor subunit gamma-21001
Gamma-aminobutyric acid receptor subunit alpha-51001
Gamma-aminobutyric acid receptor subunit alpha-31001
Gamma-aminobutyric acid receptor subunit gamma-11001
Gamma-aminobutyric acid receptor subunit alpha-21001
Gamma-aminobutyric acid receptor subunit alpha-41001
Gamma-aminobutyric acid receptor subunit gamma-31001
Gamma-aminobutyric acid receptor subunit alpha-61001
Cytochrome P450 2J20101
Gamma-aminobutyric acid receptor subunit beta-31001
Gamma-aminobutyric acid receptor subunit beta-21001
Disintegrin and metalloproteinase domain-containing protein 171001
GABA theta subunit1001
Gamma-aminobutyric acid receptor subunit epsilon1001
Integrin subunit alpha 2b0101
Integrin beta-10101
Integrin alpha-V 0101
Integrin alpha-50101
Integrin beta-3 0101
Chain A, CHORISMATE MUTASE0101
Chain A, TYROSYL-tRNA SYNTHETASE0011
Polyphenol oxidase 20001
Carbonic anhydrase 120001
Plasma kallikrein0001
Carbonic anhydrase 30001
Carbonic anhydrase 40001
Carbonic anhydrase 60001
Carbonic anhydrase 5A, mitochondrial0001
Glutamate receptor ionotropic, NMDA 1 0001
Carbonic anhydrase0001
Carbonic anhydrase 70001
Carbonic anhydrase0001
Glutamate receptor ionotropic, NMDA 2A 0001
Glutamate receptor ionotropic, NMDA 2B0001
Glutamate receptor ionotropic, NMDA 2C0001
Large neutral amino acids transporter small subunit 10101
SLC16A10 protein0001
Carbonic anhydrase 90001
Carbonic anhydrase 0001
Carbonic anhydrase-like protein, putative0001
Carbonic anhydrase0001
Carbonic anhydrase0001
Glutamate receptor ionotropic, NMDA 2D0001
Carbonic anhydrase 0001
Tubulin--tyrosine ligase0101
Glutamate receptor ionotropic, NMDA 3B0001
Monocarboxylate transporter 100001
Carbonic anhydrase 150001
Taste receptor type 2 member 140001
Glutamate receptor ionotropic, NMDA 3A0001
Carbonic anhydrase 140001
Carbonic anhydrase 5B, mitochondrial0001
nuclear factor erythroid 2-related factor 2 isoform 21001
importin subunit beta-1 isoform 11001
proteinase-activated receptor 4 preproprotein0101
snurportin-11001
survival motor neuron protein isoform d1001
Proteinase-activated receptor 10101
TAR DNA-binding protein 431001
Proteinase-activated receptor 40101
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]