Page last updated: 2024-09-27

Acute Idiopathic Blind Spot Enlargement Syndrome

A group of idiopathic multifocal posterior uveitis syndromes involving the CHOROID; RETINAL PIGMENT EPITHELIUM; and RETINA. They are characterized by multiple lesions of hypoautofluorescent dots in the FUNDUS OCULI and reduced VISUAL ACUITY. Several entities including BIRDSHOT CHORIORETINOPATHY are HLA-A ANTIGENS serotype A29 positive.

Synonyms(11)

Synonym
Serpiginous Choroiditis
APMPPE
Serpiginous Choroidopathy
Acute Idiopathic Blind Spot Enlargement Syndrome
Punctate Inner Choroidopathy
Multiple Evanescent White Dot Syndrome
MEWDS
Acute Posterior Multifocal Placoid Pigment Epitheliopathy
Acute Macular Neuroretinopathy
White Dot Syndromes
Diffuse Subretinal Fibrosis Uveitis

Research Excerpts

Overview

ExcerptReference
"The MMI findings of MEWDS are secondary to RPE reflectivity changes, suggesting its pivotal role."( Mantovani, A; Preziosa, C; Staurenghi, G; Zicarelli, F, 2020)
"Although multiple evanescent white dot syndrome is often self-limiting, to reduce the possibility of an inflammatory reaction, we preferred to administer prednisolone orally."( Lumbroso, B; Rispoli, M; Savastano, MC, 2019)

Treatment

ExcerptReference
"Although multiple evanescent white dot syndrome is often self-limiting, to reduce the possibility of an inflammatory reaction, we preferred to administer prednisolone orally."( Lumbroso, B; Rispoli, M; Savastano, MC, 2019)
"the case illustrates the association of MEWDS and choroidal neovascularization developing after COVID-19 infection in the setting of immunotherapy."( Browning, AC; Gallo, B; Pandit, RJ; Talks, JS, 2023)

Research

Studies (44)

TimeframeStudies, This Condition (%)All Conditions %
pre-19900 (0.00)23.3326
1990's0 (0.00)12.5806
2000's0 (0.00)18.1394
2010's15 (34.09)28.8240
2020's29 (65.91)9.53
DrugIndicatedRelationship StrengthStudiesTrials
azathioprine0low10
caffeine0low10
prednisolone0low60
prednisone0low100
penicillin g0low20
fluocinolone acetonide0low10
triamcinolone acetonide0low20
methylprednisolone0low30
pyrazines0low10
tacrolimus0low10
mycophenolic acid0low20
lactulose0low10
trametinib0low10
indocyanine green0low150
ro13-99040low10
dabrafenib0low10
gilteritinib0low10
eye0low20

Protein Targets (616)

ProteinPotency MeasurementsInhibition MeasurementsActivation MeasurementsDrugs
Chain A, MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASE1001
Chain A, TYROSYL-DNA PHOSPHODIESTERASE2002
Chain A, Ferritin light chain2002
interleukin 81001
acetylcholinesterase3003
thioredoxin reductase1001
phosphopantetheinyl transferase2002
RAR-related orphan receptor gamma4004
SMAD family member 24004
ATAD5 protein, partial2002
Fumarate hydratase3003
SMAD family member 34004
TDP1 protein6006
GLI family zinc finger 37007
Microtubule-associated protein tau1001
AR protein9009
thioredoxin glutathione reductase2002
nuclear receptor subfamily 1, group I, member 34004
EWS/FLI fusion protein3003
glucocorticoid receptor [Homo sapiens]9009
retinoic acid nuclear receptor alpha variant 16006
retinoid X nuclear receptor alpha5005
estrogen-related nuclear receptor alpha9009
farnesoid X nuclear receptor3003
pregnane X nuclear receptor7007
estrogen nuclear receptor alpha9009
G3003
polyprotein3003
P531001
peroxisome proliferator-activated receptor delta3003
peroxisome proliferator activated receptor gamma3003
arylsulfatase A1001
IDH13003
euchromatic histone-lysine N-methyltransferase 24004
aryl hydrocarbon receptor4004
cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a8008
thyroid stimulating hormone receptor3003
activating transcription factor 62002
v-jun sarcoma virus 17 oncogene homolog (avian)4004
Histone H2A.x2002
Bloom syndrome protein isoform 11001
peripheral myelin protein 22 isoform 11001
hemoglobin subunit beta1001
cellular tumor antigen p53 isoform a1001
thyroid hormone receptor beta isoform 25005
heat shock protein beta-12002
nuclear factor erythroid 2-related factor 2 isoform 14004
DNA polymerase iota isoform a (long)2002
geminin6006
peripheral myelin protein 223003
survival motor neuron protein isoform d2002
cytochrome P450 3A4 isoform 12002
M-phase phosphoprotein 81001
muscleblind-like protein 1 isoform 12002
muscarinic acetylcholine receptor M12002
lamin isoform A-delta104004
Gamma-aminobutyric acid receptor subunit pi2002
ATP-binding cassette sub-family C member 30606
Multidrug resistance-associated protein 40606
Bile salt export pump0101
Voltage-dependent calcium channel gamma-2 subunit4004
Bile salt export pump0707
Interferon beta5005
HLA class I histocompatibility antigen, B alpha chain 3003
Cellular tumor antigen p537007
Gamma-aminobutyric acid receptor subunit beta-12002
Gamma-aminobutyric acid receptor subunit delta2002
Gamma-aminobutyric acid receptor subunit gamma-22002
Glutamate receptor 24105
Gamma-aminobutyric acid receptor subunit alpha-52002
Gamma-aminobutyric acid receptor subunit alpha-32002
Gamma-aminobutyric acid receptor subunit gamma-12002
Gamma-aminobutyric acid receptor subunit alpha-22002
Gamma-aminobutyric acid receptor subunit alpha-42002
Gamma-aminobutyric acid receptor subunit gamma-32002
Gamma-aminobutyric acid receptor subunit alpha-62002
Nuclear receptor ROR-gamma2002
Gamma-aminobutyric acid receptor subunit alpha-12002
Gamma-aminobutyric acid receptor subunit beta-32002
Gamma-aminobutyric acid receptor subunit beta-22002
GABA theta subunit2002
Inositol hexakisphosphate kinase 13003
Canalicular multispecific organic anion transporter 10606
ATPase family AAA domain-containing protein 57007
Ataxin-27007
Gamma-aminobutyric acid receptor subunit epsilon2002
Protein-arginine deiminase type-40101
cytochrome P450 2C9, partial3003
Chain A, Glycogen Phosphorylase0101
Chain A, Glycogen phosphorylase, liver form0011
Chain A, glycogen phosphorylase, liver form0011
Chain A, Glycogen phosphorylase, liver form0011
Chain A, Glycogen phosphorylase, liver form0011
Chain A, Chitinase0101
GLS protein1001
atrial natriuretic peptide receptor 1 precursor1001
chromobox protein homolog 12002
thyroid hormone receptor beta isoform a1001
DNA polymerase beta1001
nuclear receptor ROR-gamma isoform 14004
DNA polymerase kappa isoform 12002
lethal factor (plasmid)2002
Potassium channel subfamily K member 20011
Glycogen phosphorylase, muscle form0101
Renin0101
Carbonic anhydrase 10101
Carbonic anhydrase 20101
Cholinesterase0101
Glycogen phosphorylase, liver form0101
Glycogen phosphorylase, muscle form0101
Replicase polyprotein 1ab0101
Adenosine receptor A30101
Replicase polyprotein 1ab0202
Amine oxidase [flavin-containing] A0101
Acetylcholinesterase0101
Adenosine receptor A10203
Amine oxidase [flavin-containing] B0202
cAMP-specific 3',5'-cyclic phosphodiesterase 4A0101
Adenosine receptor A30101
Adenosine receptor A2a0214
Adenosine receptor A2b0102
Adenosine receptor A2b0203
Adenosine receptor A10114
Adenosine receptor A2a0204
Vasopressin V2 receptor0001
Serine/threonine-protein kinase mTOR0202
Adenosine receptor A2a0101
Adenosine receptor A10101
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform 0101
DNA-dependent protein kinase catalytic subunit0101
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B0101
Adenylate cyclase type 10001
Chitotriosidase-10101
Serine-protein kinase ATM0101
Serine/threonine-protein kinase ATR0101
Adenosine receptor A2b0102
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C0101
Palmitoleoyl-protein carboxylesterase NOTUM0123
Endochitinase B10101
Muscarinic acetylcholine receptor0001
Phosphodiesterase 0101
Broad substrate specificity ATP-binding cassette transporter ABCG20202
Guanine deaminase0101
ATP-dependent phosphofructokinase2002
PPM1D protein3003
cytochrome P450 family 3 subfamily A polypeptide 44004
Bone morphogenetic protein receptor type-1B0033
Membrane-associated progesterone receptor component 10033
Cell division cycle 7-related protein kinase0022
Serine/threonine-protein kinase PLK40033
ATP-dependent RNA helicase DDX3X0033
Pirin0101
Pyridoxal kinase0033
Citron Rho-interacting kinase0033
Serine/threonine-protein kinase Chk10033
Aurora kinase A0033
Cyclin-G-associated kinase0033
Ephrin type-B receptor 60033
Peroxisomal acyl-coenzyme A oxidase 30033
Receptor-interacting serine/threonine-protein kinase 20134
Mitotic checkpoint serine/threonine-protein kinase BUB10033
Dynamin-like 120 kDa protein, mitochondrial0033
Tyrosine-protein kinase JAK20022
Eukaryotic translation initiation factor 5B0033
Rho-associated protein kinase 20033
Serine/threonine-protein kinase ULK10033
Serine/threonine-protein kinase/endoribonuclease IRE10033
Nuclear receptor subfamily 1 group I member 20033
Ribosomal protein S6 kinase alpha-50033
U5 small nuclear ribonucleoprotein 200 kDa helicase0033
Ribosomal protein S6 kinase alpha-40033
Serine/threonine-protein kinase 160033
Cyclin-dependent kinase-like 50033
Serine/threonine-protein kinase 100033
Serine/threonine-protein kinase D30033
Structural maintenance of chromosomes protein 20033
Mitogen-activated protein kinase kinase kinase 60033
Mitogen-activated protein kinase kinase kinase kinase 40033
Serine/threonine-protein kinase LATS10033
Serine/threonine-protein kinase PAK 40033
Tyrosine-protein kinase ABL10033
Epidermal growth factor receptor0033
GTPase KRas0101
RAF proto-oncogene serine/threonine-protein kinase0102
High affinity nerve growth factor receptor0033
Guanine nucleotide-binding protein G(i) subunit alpha-20033
ADP/ATP translocase 20033
Protein kinase C beta type0033
Insulin receptor0033
Tyrosine-protein kinase Lck0033
Tyrosine-protein kinase Fyn0033
Cyclin-dependent kinase 10134
Glycogen phosphorylase, liver form0033
Tyrosine-protein kinase Fes/Fps0033
Adenine phosphoribosyltransferase0022
Tyrosine-protein kinase Yes0033
Tyrosine-protein kinase Lyn0033
Proto-oncogene tyrosine-protein kinase receptor Ret0033
Insulin-like growth factor 1 receptor0033
Signal recognition particle receptor subunit alpha0033
Cytochrome c1, heme protein, mitochondrial0033
Hepatocyte growth factor receptor0033
Tyrosine-protein kinase HCK0033
Platelet-derived growth factor receptor beta0033
Tyrosine-protein kinase Fgr0022
Serine/threonine-protein kinase A-Raf0134
Glycogen phosphorylase, brain form0033
Breakpoint cluster region protein0033
Serine/threonine-protein kinase pim-10033
Fibroblast growth factor receptor 10033
DNA topoisomerase 2-alpha0033
Cyclin-dependent kinase 40033
ADP/ATP translocase 30033
Inosine-5'-monophosphate dehydrogenase 20235
Proto-oncogene tyrosine-protein kinase Src0033
cAMP-dependent protein kinase type II-alpha regulatory subunit0033
Serine/threonine-protein kinase B-raf0146
Phosphorylase b kinase gamma catalytic chain, liver/testis isoform0033
Ribosyldihydronicotinamide dehydrogenase [quinone]0033
Tyrosine-protein kinase Fer0033
Protein kinase C alpha type0033
cAMP-dependent protein kinase catalytic subunit alpha0033
General transcription and DNA repair factor IIH helicase subunit XPD0033
Casein kinase II subunit alpha'0033
Ras-related protein Rab-6A0033
Ephrin type-A receptor 10033
Multifunctional protein ADE20033
cAMP-dependent protein kinase catalytic subunit gamma0033
cAMP-dependent protein kinase catalytic subunit beta0033
Ferrochelatase, mitochondrial0033
Ribosomal protein S6 kinase beta-10033
Tyrosine-protein kinase JAK10033
Cyclin-dependent kinase 20134
Beta-adrenergic receptor kinase 10033
Probable ATP-dependent RNA helicase DDX60033
Mitogen-activated protein kinase 3 0033
MAP/microtubule affinity-regulating kinase 30033
Deoxycytidine kinase0033
Mitogen-activated protein kinase 10033
Ephrin type-A receptor 20033
Ephrin type-B receptor 20033
Non-receptor tyrosine-protein kinase TYK20033
UMP-CMP kinase 0022
Phosphatidylethanolamine-binding protein 10022
Wee1-like protein kinase0033
Heme oxygenase 20033
S-adenosylmethionine synthase isoform type-20033
DnaJ homolog subfamily A member 10033
RAC-alpha serine/threonine-protein kinase0033
RAC-beta serine/threonine-protein kinase0033
Dual specificity protein kinase TTK0033
DNA replication licensing factor MCM40033
Myosin-100022
Dual specificity mitogen-activated protein kinase kinase 20235
Receptor-type tyrosine-protein kinase FLT30235
Bone morphogenetic protein receptor type-1A0033
Activin receptor type-1B0033
TGF-beta receptor type-10134
Serine/threonine-protein kinase receptor R30022
TGF-beta receptor type-20033
Electron transfer flavoprotein subunit beta0033
Tyrosine-protein kinase CSK0033
Glycine--tRNA ligase0033
Protein kinase C iota type0033
Exosome RNA helicase MTR40033
Tyrosine-protein kinase Tec0033
Tyrosine-protein kinase ABL20033
Tyrosine-protein kinase FRK0033
Tyrosine-protein kinase SYK0033
26S proteasome regulatory subunit 6B0033
Mitogen-activated protein kinase 80033
Mitogen-activated protein kinase 90033
Dual specificity mitogen-activated protein kinase kinase 40022
Dual specificity mitogen-activated protein kinase kinase 30033
Phosphatidylinositol 5-phosphate 4-kinase type-2 alpha0033
Casein kinase I isoform alpha0033
Casein kinase I isoform delta0033
MAP kinase-activated protein kinase 20033
Elongation factor Tu, mitochondrial0033
Choline-phosphate cytidylyltransferase A0022
Cysteine--tRNA ligase, cytoplasmic0033
Casein kinase I isoform epsilon0033
Very long-chain specific acyl-CoA dehydrogenase, mitochondrial0033
Dual specificity protein kinase CLK10033
Dual specificity protein kinase CLK20022
Dual specificity protein kinase CLK30022
Glycogen synthase kinase-3 alpha0033
Glycogen synthase kinase-3 beta0033
Cyclin-dependent kinase 70134
Cyclin-dependent kinase 90033
Ras-related protein Rab-27A0033
Interleukin-1 receptor-associated kinase 10033
Ribosomal protein S6 kinase alpha-30033
Serine/threonine-protein kinase Nek20033
Serine/threonine-protein kinase Nek30033
Dual specificity mitogen-activated protein kinase kinase 60033
Serine/threonine-protein kinase PLK10022
LIM domain kinase 10033
LIM domain kinase 20033
Mitogen-activated protein kinase 100033
Tyrosine--tRNA ligase, cytoplasmic0033
5'-AMP-activated protein kinase subunit gamma-10033
Ephrin type-B receptor 30033
Ephrin type-A receptor 50033
Ephrin type-B receptor 40033
Ephrin type-A receptor 40033
Adenylate kinase 2, mitochondrial0033
Adenosine kinase0033
Ras-related protein Rab-100033
Actin-related protein 30033
Actin-related protein 20033
GTP-binding nuclear protein Ran0033
Casein kinase I isoform gamma-20033
Cyclin-dependent kinase 30033
Cyclin-dependent kinase 60033
Cyclin-dependent-like kinase 5 0033
Cyclin-dependent kinase 160033
Cyclin-dependent kinase 170033
Heat shock factor protein 10101
ATP-dependent 6-phosphofructokinase, platelet type0033
Dual specificity mitogen-activated protein kinase kinase 10235
DNA topoisomerase 2-beta0033
Protein kinase C theta type0022
Activin receptor type-10033
Macrophage-stimulating protein receptor0033
Focal adhesion kinase 10033
Protein kinase C zeta type0022
Protein kinase C delta type0033
Tyrosine-protein kinase BTK0033
Activated CDC42 kinase 10033
Epithelial discoidin domain-containing receptor 10033
Mitogen-activated protein kinase kinase kinase kinase 20033
Tyrosine-protein kinase Mer0011
Serine/threonine-protein kinase 40033
5'-AMP-activated protein kinase catalytic subunit alpha-10033
Dual specificity mitogen-activated protein kinase kinase 50033
Mitogen-activated protein kinase 70033
Serine/threonine-protein kinase PAK 20022
Serine/threonine-protein kinase 30033
Mitogen-activated protein kinase kinase kinase 10033
Integrin-linked protein kinase0033
Rho-associated protein kinase 10033
Non-receptor tyrosine-protein kinase TNK10033
Receptor-interacting serine/threonine-protein kinase 10101
Calcium/calmodulin-dependent protein kinase type II subunit gamma0033
Calcium/calmodulin-dependent protein kinase type II subunit delta0033
Dual specificity tyrosine-phosphorylation-regulated kinase 1A0033
Activin receptor type-2B0033
Bone morphogenetic protein receptor type-20033
Protein-tyrosine kinase 60033
cGMP-dependent protein kinase 1 0033
Cyclin-dependent kinase 130033
Inhibitor of nuclear factor kappa-B kinase subunit epsilon0033
Protein-tyrosine kinase 2-beta0033
Maternal embryonic leucine zipper kinase0033
Structural maintenance of chromosomes protein 1A0033
Chromodomain-helicase-DNA-binding protein 40033
Peroxisomal acyl-coenzyme A oxidase 10022
Cyclin-dependent kinase 100022
Ephrin type-A receptor 70033
Delta(24)-sterol reductase0033
Ribosomal protein S6 kinase alpha-10033
Dual specificity testis-specific protein kinase 10033
Myosin light chain kinase, smooth muscle0033
Mitogen-activated protein kinase 110033
Serine/threonine-protein kinase STK110033
Serine/threonine-protein kinase N10033
Serine/threonine-protein kinase N20033
Mitogen-activated protein kinase 140033
Calcium/calmodulin-dependent protein kinase type IV0033
Mitogen-activated protein kinase kinase kinase 110033
MAP kinase-activated protein kinase 30022
Discoidin domain-containing receptor 20033
AP2-associated protein kinase 10033
Myosin light chain kinase 30033
Uncharacterized aarF domain-containing protein kinase 50022
Putative heat shock protein HSP 90-beta 20033
Rab-like protein 30033
Serine/threonine-protein kinase MRCK alpha0033
Serine/threonine-protein kinase MRCK gamma0022
Acyl-CoA dehydrogenase family member 100033
Serine/threonine-protein kinase N30022
Serine/threonine-protein kinase ULK30033
Dual serine/threonine and tyrosine protein kinase0101
Uncharacterized protein FLJ452520033
Acyl-CoA dehydrogenase family member 110033
Serine/threonine-protein kinase/endoribonuclease IRE20033
Serine/threonine-protein kinase MARK20033
ATP-dependent RNA helicase DHX300033
Serine/threonine-protein kinase TAO10033
STE20-related kinase adapter protein alpha0033
Myosin-140033
AarF domain-containing protein kinase 10033
ATP-dependent RNA helicase DDX420022
Mitogen-activated protein kinase kinase kinase kinase 30033
MAP kinase-activated protein kinase 50033
Eukaryotic peptide chain release factor GTP-binding subunit ERF3B0022
Misshapen-like kinase 10022
Atypical kinase COQ8A, mitochondrial0033
Phosphatidylinositol 5-phosphate 4-kinase type-2 gamma0033
Mitogen-activated protein kinase 150033
Serine/threonine-protein kinase Nek90033
ATP-dependent RNA helicase DDX10022
Mitogen-activated protein kinase kinase kinase kinase 10033
Aurora kinase B0033
MAP/microtubule affinity-regulating kinase 40033
Serine/threonine-protein kinase Nek10033
PAS domain-containing serine/threonine-protein kinase0022
Calcium/calmodulin-dependent protein kinase kinase 20033
EKC/KEOPS complex subunit TP53RK0033
Dual specificity testis-specific protein kinase 20022
Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase0033
Mitogen-activated protein kinase kinase kinase 50033
Mitogen-activated protein kinase kinase kinase 30033
Eukaryotic translation initiation factor 2-alpha kinase 10033
Nucleolar GTP-binding protein 10033
Serine/threonine-protein kinase D20033
NUAK family SNF1-like kinase 20033
RNA cytidine acetyltransferase0033
Serine/threonine-protein kinase SIK20033
STE20-like serine/threonine-protein kinase 0033
Serine/threonine-protein kinase TAO30033
dCTP pyrophosphatase 10033
Dual specificity protein kinase CLK40033
Casein kinase I isoform gamma-10033
Serine/threonine-protein kinase PAK 60022
Phenylalanine--tRNA ligase beta subunit0033
Isoleucine--tRNA ligase, mitochondrial0022
BMP-2-inducible protein kinase0033
Obg-like ATPase 10022
Midasin0033
Interleukin-1 receptor-associated kinase 40033
Mitogen-activated protein kinase kinase kinase 200033
Cyclin-dependent kinase 120033
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 130033
Serine/threonine-protein kinase pim-20022
Serine/threonine-protein kinase 260033
Serine/threonine-protein kinase NLK0033
5'-AMP-activated protein kinase subunit gamma-20033
Serine/threonine-protein kinase TBK10033
Septin-90033
Ribosomal protein S6 kinase alpha-60033
TRAF2 and NCK-interacting protein kinase0033
Serine/threonine-protein kinase TAO20033
Serine/threonine-protein kinase ICK0033
RAC-gamma serine/threonine-protein kinase0033
Serine/threonine-protein kinase SIK30033
Mitogen-activated protein kinase kinase kinase 20033
Thyroid hormone receptor-associated protein 30033
Dual specificity tyrosine-phosphorylation-regulated kinase 1B0022
Mitogen-activated protein kinase kinase kinase kinase 50033
Receptor-interacting serine/threonine-protein kinase 30134
Serine/threonine-protein kinase MRCK beta0033
Interleukin-1 receptor-associated kinase 30033
Serine/threonine-protein kinase 240033
Casein kinase I isoform gamma-30033
Mitogen-activated protein kinase kinase kinase 40033
Chain A, 2-oxoglutarate Oxygenase2002
Smad31001
hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)4004
progesterone receptor6006
vitamin D (1,25- dihydroxyvitamin D3) receptor4004
nuclear receptor subfamily 1, group I, member 24004
mitogen-activated protein kinase 11001
urokinase-type plasminogen activator precursor2002
plasminogen precursor2002
urokinase plasminogen activator surface receptor precursor2002
Glucocorticoid receptor010217
Glycine receptor subunit alpha-1010010
Glycine receptor subunit beta010010
Glycine receptor subunit alpha-2010010
Glycine receptor subunit alpha-3010010
G2/mitotic-specific cyclin-B10101
Cannabinoid receptor 10101
G1/S-specific cyclin-E10101
Leukocyte tyrosine kinase receptor0102
Tyrosine-protein kinase receptor UFO0101
Transcription factor ETV60101
Cyclin-H0101
CDK-activating kinase assembly factor MAT10101
Ras-related C3 botulinum toxin substrate 10011
Serine/threonine-protein kinase 380011
Echinoderm microtubule-associated protein-like 40101
Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial0022
Long-chain-fatty-acid--CoA ligase 50011
ALK tyrosine kinase receptor0101
hypoxia-inducible factor 1 alpha subunit3003
nonstructural protein 11001
bromodomain adjacent to zinc finger domain 2B1001
nuclear factor erythroid 2-related factor 2 isoform 25005
Androgen receptor0303
Nuclear receptor subfamily 1 group I member 20011
Chain A, Inosine-5'-Monophosphate Dehydrogenase 20101
Chain A, HADH2 protein2002
Chain B, HADH2 protein2002
glp-1 receptor, partial1001
aldehyde dehydrogenase 1 family, member A12002
estrogen receptor 2 (ER beta)2002
67.9K protein1001
nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105), isoform CRA_a2002
15-hydroxyprostaglandin dehydrogenase [NAD(+)] isoform 11001
UDP-glucuronosyltransferase 1A90001
Glutamate receptor 10101
Glutamate receptor 30101
Glutamate receptor 40101
Inosine-5'-monophosphate dehydrogenase 1 0202
UDP-glucuronosyltransferase 1A1 0001
Sodium-dependent serotonin transporter0101
Peroxisome proliferator-activated receptor gamma0011
Alpha-synuclein1001
TAR DNA-binding protein 432002
Inosine-5'-monophosphate dehydrogenase0102
UDP-glucuronosyltransferase 1A70001
UDP-glucuronosyltransferase 1A100001
UDP-glucuronosyltransferase 1A80001
Beta-lactamase 0001
Beta-lactamase 0001
Beta-lactamase 0001
Beta-lactamase 0001
Beta-lactamase 0001
Beta-lactamase 0001
Beta-lactamase 0001
Beta-lactamase 0001
Beta-lactamase 0001
Metallo-beta-lactamase type 20001
Metallo-beta-lactamase VIM-11 0001
Beta-lactamase 0001
Metallo-beta-lactamase VIM-20001
Beta-lactamase 0001
Metallo-beta-lactamase VIM-19 0001
Beta-lactamase 0001
Beta-lactamase 0001
Metallo-beta-lactamase0001
Beta-lactamase 0001
streptokinase A precursor0011
Solute carrier family 22 member 60101
Beta-lactamase0001
Solute carrier family 22 member 80102
Beta-lactamase0001
Beta-lactamase 10001
Beta-lactamase0001
Beta-lactamase SHV-10001
Beta-lactamase SHV-10001
Beta-lactamase OXA-100001
Beta-lactamase0001
Beta-lactamase0001
Kappa-type opioid receptor0001
Solute carrier family 15 member 10101
Beta-lactamase TEM0102
Guanine nucleotide-binding protein G1001
Beta-lactamase0001
B2 metallo-beta-lactamase 0001
Solute carrier family 15 member 20101
Metallo-beta-lactamase VIM-130001
Beta-lactamase 0001
Beta-lactamase 0001
Efflux transporter 0001
Beta-lactamase 0001
Metallo-beta-lactamase VIM-20001
Beta-lactamase Toho-10001
Beta-lactamase 0001
Beta-lactamase 0001
Class D beta-lactamase0001
Beta-lactamase 0001
Solute carrier family 15 member 20101
Beta-lactamase 0001
Beta-lactamase 0001
Beta-lactamase 0001
Beta-lactamase 0001
Metallo-b-lactamase 0001
Beta-lactamase IMP-1 0001
BlaVIM-1 0001
Beta-lactamase 0001
Beta-lactamase 0001
Solute carrier family 22 member 80101
Beta-lactamase 0001
Carbapenem-hydrolyzing beta-lactamase KPC0001
Beta-lactamase class B VIM-2 0001
Beta-lactamase 0001
Solute carrier family 22 member 80102
Beta-lactamase VIM-1 0001
luciferase0001
Fatty acid-binding protein, liver0101
Estrogen receptor0202
Progesterone receptor0203
Glucocorticoid receptor0112
Glucocorticoid receptor0011
Corticosteroid-binding globulin0101
Mineralocorticoid receptor 0213
Androgen receptor0202
Cytochrome P450 2C9 0101
Glutamine synthetase0011
Histamine H1 receptor0011
Prostaglandin G/H synthase 20101
Nociceptin receptor0011
Cytochrome P450 2J20101
Estrogen receptor beta0202
pregnane X receptor1001
vitamin D3 receptor isoform VDRA1001
USP1 protein, partial1001
Cytochrome P450 3A40101
UDP-glucuronosyltransferase 2B70001
Cytochrome P450 3A50101
UDP-glucuronosyltransferase 1A40001
Spike glycoprotein2002
Peptidyl-prolyl cis-trans isomerase FKBP1A0213
Peptidyl-prolyl cis-trans isomerase FKBP1B0011
Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform0101
Peptidyl-prolyl cis-trans isomerase FKBP50101
Splicing factor 3B subunit 30101
Solute carrier organic anion transporter family member 1B10101
ATP-dependent translocase ABCB10011
G protein-coupled receptor kinase 60011
Cyclin-dependent kinase 180011
Chain A, Beta-lactamase1001
cytochrome P450 2D61001
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]