| Protein | Potency Measurements | Inhibition Measurements | Activation Measurements | Drugs |
|---|
| hypoxia-inducible factor 1 alpha subunit | 2 | 0 | 0 | 2 |
| RAR-related orphan receptor gamma | 6 | 0 | 0 | 6 |
| GLI family zinc finger 3 | 5 | 0 | 0 | 5 |
| AR protein | 5 | 0 | 0 | 5 |
| aldehyde dehydrogenase 1 family, member A1 | 3 | 0 | 0 | 3 |
| retinoic acid nuclear receptor alpha variant 1 | 3 | 0 | 0 | 3 |
| retinoid X nuclear receptor alpha | 5 | 0 | 0 | 5 |
| estrogen nuclear receptor alpha | 5 | 0 | 0 | 5 |
| peroxisome proliferator-activated receptor delta | 2 | 0 | 0 | 2 |
| cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a | 2 | 0 | 0 | 2 |
| activating transcription factor 6 | 1 | 0 | 0 | 1 |
| v-jun sarcoma virus 17 oncogene homolog (avian) | 1 | 0 | 0 | 1 |
| Histone H2A.x | 2 | 0 | 0 | 2 |
| thyroid hormone receptor beta isoform a | 4 | 0 | 0 | 4 |
| heat shock protein beta-1 | 1 | 0 | 0 | 1 |
| nuclear factor erythroid 2-related factor 2 isoform 1 | 5 | 0 | 0 | 5 |
| lamin isoform A-delta10 | 3 | 0 | 0 | 3 |
| Voltage-dependent calcium channel gamma-2 subunit | 2 | 0 | 0 | 2 |
| Glutamate receptor 2 | 2 | 0 | 0 | 2 |
| Chain A, TYROSYL-DNA PHOSPHODIESTERASE | 1 | 0 | 0 | 1 |
| Chain A, CARBONIC ANHYDRASE II | 0 | 0 | 1 | 1 |
| Chain A, CARBONIC ANHYDRASE II | 0 | 0 | 1 | 1 |
| Chain A, CARBONIC ANHYDRASE II | 0 | 0 | 1 | 1 |
| Chain A, Carbonic Anhydrase Ii | 0 | 0 | 1 | 1 |
| Chain A, Carbonic Anhydrase Ii | 0 | 0 | 1 | 1 |
| Chain A, Beta-lactamase | 3 | 0 | 0 | 3 |
| Chain A, Endochitinase | 0 | 1 | 0 | 1 |
| Chain A, Endochitinase | 0 | 1 | 0 | 1 |
| Chain A, Endochitinase | 0 | 1 | 0 | 1 |
| Chain A, Class Iii Chitinase Chia1 | 0 | 1 | 0 | 1 |
| Chain A, Carbonic anhydrase 13 | 0 | 1 | 0 | 1 |
| Chain A, Carbonic anhydrase II | 0 | 1 | 0 | 1 |
| Chain A, Carbonic anhydrase 2 | 0 | 1 | 0 | 1 |
| Chain A, Carbonic anhydrase 2 | 0 | 1 | 0 | 1 |
| Chain A, Carbonic anhydrase 2 | 0 | 1 | 0 | 1 |
| Chain A, Carbonic anhydrase 2 | 0 | 1 | 0 | 1 |
| Chain A, Carbonic anhydrase 2 | 0 | 1 | 0 | 1 |
| Chain A, Carbonic anhydrase 2 | 0 | 1 | 0 | 1 |
| Chain A, Carbonic anhydrase 2 | 0 | 1 | 0 | 1 |
| Chain A, Carbonic anhydrase 2 | 0 | 1 | 0 | 1 |
| Chain A, Carbonic anhydrase 2 | 0 | 1 | 0 | 1 |
| Chain A, Carbonic anhydrase | 0 | 1 | 0 | 1 |
| Chain B, Carbonic anhydrase | 0 | 1 | 0 | 1 |
| Chain A, Carbonic anhydrase 2 | 0 | 1 | 0 | 1 |
| Carbonic anhydrase | 0 | 0 | 0 | 1 |
| Carbonic anhydrase | 0 | 1 | 0 | 1 |
| thioredoxin reductase | 4 | 0 | 0 | 4 |
| GALC protein | 2 | 0 | 0 | 2 |
| nuclear receptor subfamily 1, group I, member 3 | 2 | 0 | 0 | 2 |
| cytochrome P450 family 3 subfamily A polypeptide 4 | 2 | 0 | 0 | 2 |
| glucocorticoid receptor [Homo sapiens] | 3 | 0 | 0 | 3 |
| estrogen-related nuclear receptor alpha | 5 | 0 | 0 | 5 |
| Carbonic anhydrase | 0 | 1 | 0 | 1 |
| Carbonic anhydrase | 0 | 1 | 0 | 1 |
| arylsulfatase A | 2 | 0 | 0 | 2 |
| Carbonic anhydrase | 0 | 1 | 0 | 1 |
| euchromatic histone-lysine N-methyltransferase 2 | 5 | 0 | 0 | 5 |
| Bloom syndrome protein isoform 1 | 3 | 0 | 0 | 3 |
| geminin | 4 | 0 | 0 | 4 |
| peripheral myelin protein 22 | 2 | 0 | 0 | 2 |
| survival motor neuron protein isoform d | 1 | 0 | 0 | 1 |
| muscleblind-like protein 1 isoform 1 | 1 | 0 | 0 | 1 |
| Gamma-aminobutyric acid receptor subunit pi | 1 | 1 | 0 | 2 |
| ATP-binding cassette sub-family C member 3 | 0 | 2 | 0 | 2 |
| Multidrug resistance-associated protein 4 | 0 | 2 | 0 | 2 |
| Carbonic anhydrase | 0 | 1 | 0 | 1 |
| Solute carrier family 22 member 6 | 0 | 1 | 0 | 1 |
| Carbonic anhydrase 12 | 0 | 2 | 1 | 5 |
| Prolyl endopeptidase | 0 | 1 | 0 | 1 |
| Carbonic anhydrase-related protein 11 | 0 | 1 | 0 | 2 |
| Bile salt export pump | 0 | 4 | 0 | 4 |
| Glycogen phosphorylase, muscle form | 0 | 1 | 0 | 1 |
| Renin | 0 | 2 | 0 | 2 |
| Carbonic anhydrase 1 | 0 | 2 | 1 | 7 |
| Carbonic anhydrase 2 | 0 | 2 | 1 | 6 |
| Carbonic anhydrase 2 | 0 | 2 | 0 | 2 |
| Cytochrome P450 1A2 | 0 | 1 | 0 | 1 |
| Carbonic anhydrase 3 | 0 | 2 | 1 | 5 |
| Cathepsin B | 0 | 1 | 0 | 1 |
| Cytochrome P450 3A4 | 0 | 2 | 0 | 2 |
| Steryl-sulfatase | 0 | 1 | 0 | 1 |
| 5-hydroxytryptamine receptor 2C | 0 | 1 | 0 | 1 |
| Polyunsaturated fatty acid 5-lipoxygenase | 0 | 1 | 0 | 1 |
| Cytochrome P450 2C8 | 0 | 1 | 0 | 1 |
| Cytochrome P450 2D6 | 0 | 1 | 0 | 1 |
| Cytochrome P450 2A6 | 0 | 1 | 0 | 1 |
| Cytochrome P450 2C9 | 0 | 1 | 0 | 1 |
| 5-hydroxytryptamine receptor 2A | 0 | 1 | 0 | 1 |
| Androgen receptor | 0 | 1 | 0 | 1 |
| Gamma-aminobutyric acid receptor subunit beta-1 | 1 | 1 | 0 | 2 |
| Translocator protein | 0 | 1 | 0 | 1 |
| Gamma-aminobutyric acid receptor subunit delta | 1 | 1 | 0 | 2 |
| Gamma-aminobutyric acid receptor subunit gamma-2 | 1 | 1 | 0 | 2 |
| Gamma-aminobutyric acid receptor subunit alpha-5 | 1 | 1 | 0 | 2 |
| Gamma-aminobutyric acid receptor subunit alpha-3 | 1 | 1 | 0 | 2 |
| Cannabinoid receptor 1 | 0 | 1 | 0 | 1 |
| Arachidonate 5-lipoxygenase-activating protein | 0 | 1 | 0 | 1 |
| Cytochrome P450 2B6 | 0 | 1 | 0 | 1 |
| Carbonic anhydrase 4 | 0 | 2 | 1 | 4 |
| Carbonic anhydrase 6 | 0 | 2 | 1 | 4 |
| Gamma-aminobutyric acid receptor subunit gamma-1 | 1 | 1 | 0 | 2 |
| Gamma-aminobutyric acid receptor subunit alpha-2 | 1 | 1 | 0 | 2 |
| Carbonic anhydrase 5A, mitochondrial | 0 | 1 | 0 | 1 |
| Adenosine receptor A1 | 0 | 1 | 0 | 1 |
| Serum paraoxonase/arylesterase 1 | 0 | 1 | 0 | 1 |
| Dipeptidyl peptidase 4 | 0 | 0 | 0 | 1 |
| Gamma-aminobutyric acid receptor subunit alpha-4 | 1 | 1 | 0 | 2 |
| Gamma-aminobutyric acid receptor subunit gamma-3 | 1 | 1 | 0 | 2 |
| Endochitinase | 0 | 1 | 0 | 1 |
| Gamma-aminobutyric acid receptor subunit alpha-6 | 1 | 1 | 0 | 2 |
| Adenosine receptor A2a | 0 | 1 | 0 | 1 |
| 5-hydroxytryptamine receptor 2B | 0 | 1 | 0 | 1 |
| Sodium-dependent serotonin transporter | 0 | 1 | 0 | 1 |
| Delta-type opioid receptor | 0 | 1 | 0 | 1 |
| Cytochrome P450 2C19 | 0 | 1 | 0 | 1 |
| Delta-type opioid receptor | 0 | 1 | 0 | 1 |
| Mu-type opioid receptor | 0 | 1 | 0 | 1 |
| Carbonic anhydrase 5A, mitochondrial | 0 | 2 | 1 | 5 |
| Carbonic anhydrase | 0 | 1 | 0 | 1 |
| Kappa-type opioid receptor | 0 | 1 | 0 | 1 |
| Carbonic anhydrase 7 | 0 | 2 | 1 | 4 |
| Carbonic anhydrase | 0 | 1 | 0 | 1 |
| D(1A) dopamine receptor | 0 | 1 | 0 | 1 |
| Corticosteroid 11-beta-dehydrogenase isozyme 1 | 0 | 1 | 0 | 1 |
| Carbonic anhydrase | 0 | 1 | 0 | 1 |
| D(2) dopamine receptor | 0 | 1 | 0 | 1 |
| Gamma-aminobutyric acid receptor subunit alpha-1 | 1 | 1 | 0 | 2 |
| Gamma-aminobutyric acid receptor subunit beta-3 | 1 | 1 | 0 | 2 |
| Gamma-aminobutyric acid receptor subunit beta-2 | 1 | 1 | 0 | 2 |
| Cholinesterase | 0 | 1 | 0 | 1 |
| Carbonic anhydrase | 0 | 1 | 0 | 1 |
| Mu-type opioid receptor | 0 | 1 | 0 | 1 |
| Fatty-acid amide hydrolase 1 | 0 | 1 | 0 | 1 |
| Beta-carbonic anhydrase 1 | 0 | 1 | 0 | 1 |
| Carbonic anhydrase 2 | 0 | 1 | 0 | 1 |
| Glutamate receptor ionotropic, NMDA 2B | 0 | 1 | 0 | 1 |
| Squalene synthase | 0 | 1 | 0 | 1 |
| Neuronal acetylcholine receptor subunit alpha-7 | 0 | 1 | 0 | 1 |
| Carbonic anhydrase 9 | 0 | 2 | 1 | 5 |
| Carbonic anhydrase | 0 | 1 | 0 | 1 |
| Carbonic anhydrase, alpha family | 0 | 1 | 0 | 1 |
| Carbonic anhydrase | 0 | 1 | 0 | 1 |
| Carbonic anhydrase 3 | 0 | 1 | 0 | 1 |
| Carbonic anhydrase | 0 | 1 | 0 | 2 |
| Carbonic anhydrase | 0 | 1 | 0 | 2 |
| Carbonic anhydrase | 0 | 1 | 0 | 1 |
| Sigma intracellular receptor 2 | 0 | 1 | 0 | 1 |
| Delta carbonic anhydrase | 0 | 1 | 0 | 1 |
| Sigma non-opioid intracellular receptor 1 | 0 | 1 | 0 | 1 |
| Renin | 0 | 1 | 0 | 1 |
| Carbonic anhydrase | 0 | 1 | 0 | 1 |
| Endochitinase A1 | 0 | 1 | 0 | 1 |
| Multidrug resistance-associated protein 1 | 0 | 1 | 0 | 1 |
| Carbonic anhydrase 13 | 0 | 2 | 1 | 4 |
| GABA theta subunit | 1 | 1 | 0 | 2 |
| Canalicular multispecific organic anion transporter 1 | 0 | 2 | 0 | 2 |
| Carbonic anhydrase 4 | 0 | 2 | 0 | 2 |
| Carbonic anhydrase 15 | 0 | 1 | 0 | 2 |
| Acidic mammalian chitinase | 0 | 1 | 0 | 1 |
| Carbonic anhydrase 13 | 0 | 2 | 0 | 3 |
| Carbonic anhydrase 7 | 0 | 1 | 0 | 1 |
| Gamma-aminobutyric acid receptor subunit epsilon | 1 | 1 | 0 | 2 |
| Carbonic anhydrase | 0 | 1 | 0 | 1 |
| Carbonic anhydrase 14 | 0 | 2 | 1 | 5 |
| Carbonic anhydrase | 0 | 1 | 0 | 1 |
| Carbonic anhydrase 2, isoform A | 0 | 1 | 0 | 1 |
| Carbonic anhydrase 5B, mitochondrial | 0 | 2 | 1 | 5 |
| Luciferase | 1 | 0 | 0 | 1 |
| progesterone receptor | 2 | 0 | 0 | 2 |
| pregnane X nuclear receptor | 2 | 0 | 0 | 2 |
| peroxisome proliferator activated receptor gamma | 3 | 0 | 0 | 3 |
| vitamin D (1,25- dihydroxyvitamin D3) receptor | 3 | 0 | 0 | 3 |
| ATAD5 protein, partial | 1 | 0 | 0 | 1 |
| Chymotrypsinogen A | 0 | 1 | 0 | 1 |
| ATP-dependent phosphofructokinase | 1 | 0 | 0 | 1 |
| Chain A, MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASE | 2 | 0 | 0 | 2 |
| GLS protein | 1 | 0 | 0 | 1 |
| TDP1 protein | 4 | 0 | 0 | 4 |
| Microtubule-associated protein tau | 1 | 0 | 0 | 1 |
| IDH1 | 2 | 0 | 0 | 2 |
| chromobox protein homolog 1 | 3 | 0 | 0 | 3 |
| mitogen-activated protein kinase 1 | 1 | 0 | 0 | 1 |
| flap endonuclease 1 | 1 | 0 | 0 | 1 |
| cytochrome P450 3A4 isoform 1 | 1 | 0 | 0 | 1 |
| muscarinic acetylcholine receptor M1 | 2 | 0 | 0 | 2 |
| Potassium channel subfamily K member 3 | 0 | 1 | 0 | 1 |
| Potassium channel subfamily K member 2 | 0 | 1 | 0 | 1 |
| Sodium channel protein type 1 subunit alpha | 0 | 1 | 0 | 1 |
| Sodium channel protein type 2 subunit alpha | 0 | 1 | 0 | 1 |
| Sodium channel protein type 3 subunit alpha | 0 | 1 | 0 | 1 |
| Potassium voltage-gated channel subfamily A member 5 | 0 | 1 | 0 | 1 |
| Sodium channel protein type 4 subunit alpha | 0 | 1 | 0 | 1 |
| Potassium voltage-gated channel subfamily H member 2 | 0 | 1 | 0 | 1 |
| Sodium channel protein type 5 subunit alpha | 0 | 1 | 0 | 1 |
| Sodium channel protein type 9 subunit alpha | 0 | 1 | 0 | 1 |
| Potassium voltage-gated channel subfamily D member 2 | 0 | 1 | 0 | 1 |
| Potassium channel subfamily K member 18 | 0 | 1 | 0 | 1 |
| Multidrug and toxin extrusion protein 1 | 0 | 1 | 0 | 1 |
| Sodium channel protein type 3 subunit alpha | 0 | 1 | 0 | 1 |
| Chain A, 2-oxoglutarate Oxygenase | 1 | 0 | 0 | 1 |
| glp-1 receptor, partial | 2 | 0 | 0 | 2 |
| hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 1 | 0 | 0 | 1 |
| thyroid stimulating hormone receptor | 1 | 0 | 0 | 1 |
| beta-2 adrenergic receptor | 1 | 0 | 0 | 1 |
| lysosomal alpha-glucosidase preproprotein | 1 | 0 | 0 | 1 |
| mu-type opioid receptor isoform MOR-1 | 0 | 0 | 1 | 1 |
| Vpr | 1 | 0 | 0 | 1 |
| 5-hydroxytryptamine receptor 2A | 0 | 0 | 1 | 1 |
| Cellular tumor antigen p53 | 2 | 0 | 0 | 2 |
| Neuronal acetylcholine receptor subunit alpha-4 | 1 | 0 | 0 | 1 |
| Neuronal acetylcholine receptor subunit beta-2 | 1 | 0 | 0 | 1 |
| Spike glycoprotein | 1 | 0 | 0 | 1 |
| thyroid stimulating hormone receptor | 1 | 0 | 0 | 1 |
| cytochrome P450 2D6 isoform 1 | 1 | 0 | 0 | 1 |
| histone acetyltransferase KAT2A isoform 1 | 1 | 0 | 0 | 1 |
| Chain A, Ferritin light chain | 1 | 0 | 0 | 1 |
| pregnane X receptor | 1 | 0 | 0 | 1 |
| phosphopantetheinyl transferase | 1 | 0 | 0 | 1 |
| SMAD family member 2 | 1 | 0 | 0 | 1 |
| SMAD family member 3 | 1 | 0 | 0 | 1 |
| estrogen receptor 2 (ER beta) | 1 | 0 | 0 | 1 |
| nonstructural protein 1 | 1 | 0 | 0 | 1 |
| farnesoid X nuclear receptor | 2 | 0 | 0 | 2 |
| heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 1 | 0 | 0 | 1 |
| aryl hydrocarbon receptor | 1 | 0 | 0 | 1 |
| vitamin D3 receptor isoform VDRA | 1 | 0 | 0 | 1 |
| thyroid hormone receptor beta isoform 2 | 1 | 0 | 0 | 1 |
| heat shock protein HSP 90-alpha isoform 2 | 0 | 0 | 0 | 1 |
| DNA polymerase iota isoform a (long) | 1 | 0 | 0 | 1 |
| nuclear receptor ROR-gamma isoform 1 | 1 | 0 | 0 | 1 |
| Polyunsaturated fatty acid lipoxygenase ALOX15B | 1 | 0 | 0 | 1 |
| Histamine H2 receptor | 1 | 0 | 0 | 1 |
| Guanine nucleotide-binding protein G | 1 | 0 | 0 | 1 |
| TAR DNA-binding protein 43 | 1 | 0 | 0 | 1 |
| ATPase family AAA domain-containing protein 5 | 1 | 0 | 0 | 1 |
| Ataxin-2 | 1 | 0 | 0 | 1 |
| heat shock protein 90, putative | 0 | 0 | 0 | 1 |
| Cereblon isoform 4 | 0 | 2 | 0 | 2 |
| EWS/FLI fusion protein | 1 | 0 | 0 | 1 |
| cytochrome P450 2D6 | 1 | 0 | 0 | 1 |
| Prostaglandin G/H synthase 1 | 0 | 1 | 0 | 1 |
| cAMP-specific 3',5'-cyclic phosphodiesterase 4A | 0 | 1 | 0 | 1 |
| Prostaglandin G/H synthase 2 | 0 | 1 | 0 | 1 |
| cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 0 | 1 | 0 | 1 |
| cAMP-specific 3',5'-cyclic phosphodiesterase 4C | 0 | 1 | 0 | 1 |
| cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 0 | 1 | 0 | 1 |
| DNA-binding protein Ikaros | 0 | 0 | 0 | 1 |
| DNA damage-binding protein 1 | 0 | 1 | 1 | 2 |
| Protein cereblon | 0 | 2 | 1 | 4 |
| [prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023] |