Page last updated: 2024-09-27

Accident Injury

Injuries resulting from events or circumstances that are unforeseen, unplanned, unanticipated, and without premeditation.

Synonyms(3)

Synonym
Accident Injury
Accidental Injury
Accidental Injuries

Research Excerpts

Research

Studies (24)

TimeframeStudies, This Condition (%)All Conditions %
pre-19900 (0.00)23.3326
1990's0 (0.00)12.5806
2000's0 (0.00)18.1394
2010's8 (33.33)28.8240
2020's16 (66.67)9.53
DrugIndicatedRelationship StrengthStudiesTrials
melatonin0low10
alprazolam0low10
caffeine0low10
cefuroxime0low10
chlorpyrifos0low10
clonazepam0low10
valproic acid0low10
donepezil0low10
lamotrigine0low10
adenosine monophosphate0low10
galantamine0low10
trolamine salicylate0low10
propiconazole0low20
atorvastatin0low10
rivastigmine0low10
sodium bicarbonate0low10
freedom0low10
humulene0low10
hydrocodone0low10
levetiracetam0low10
cangrelor0low10
palytoxin0low10
rome0low10
exudates0medium11

Protein Targets (391)

ProteinPotency MeasurementsInhibition MeasurementsActivation MeasurementsDrugs
Chain A, Glycogen Phosphorylase B0011
Chain B, Glycogen Phosphorylase B0011
Chain A, ADP-dependent glucokinase0101
Chain A, Ribonuclease pancreatic0101
Chain A, Ribonuclease pancreatic0101
Chain A, phosphodiesterase-nucleotide pyrophosphatase0101
Chain A, GLYCOGEN PHOSPHORYLASE B0011
Chain B, GLYCOGEN PHOSPHORYLASE B0011
Chain A, GLYCOGEN PHOSPHORYLASE B0011
RAR-related orphan receptor gamma7007
AR protein7007
regulator of G-protein signaling 42002
glucocorticoid receptor [Homo sapiens]6006
estrogen-related nuclear receptor alpha6006
euchromatic histone-lysine N-methyltransferase 26006
v-jun sarcoma virus 17 oncogene homolog (avian)3003
2'-deoxynucleoside 5'-phosphate N-hydrolase 10101
Mitogen-activated protein kinase kinase kinase 70011
2'-deoxynucleoside 5'-phosphate N-hydrolase 10101
5'-AMP-activated protein kinase subunit beta-20011
Transient receptor potential cation channel subfamily M member 20101
Alcohol dehydrogenase E chain0101
Alcohol dehydrogenase S chain0101
L-lactate dehydrogenase A chain0112
Adenylate kinase isoenzyme 10001
Fructose-1,6-bisphosphatase 10101
Alkaline phosphatase, tissue-nonspecific isozyme0001
Fructose-1,6-bisphosphatase 10101
2-dehydropantoate 2-reductase0112
Inosine-5'-monophosphate dehydrogenase0101
Cytochrome P450 2C9 0101
Proto-oncogene tyrosine-protein kinase Src0101
Amine oxidase [flavin-containing] B0303
5'-nucleotidase0001
Choline O-acetyltransferase0101
Adenylate kinase 2, mitochondrial0102
GTP:AMP phosphotransferase AK3, mitochondrial0001
Adenosine receptor A10125
Adenylate kinase isoenzyme 1 0102
P2Y purinoceptor 20011
P2Y purinoceptor 10011
P2Y purinoceptor 10011
5'-AMP-activated protein kinase subunit gamma-10022
5'-AMP-activated protein kinase catalytic subunit alpha-20011
Adenylate kinase 2, mitochondrial0001
Glycine--tRNA ligase0101
5'-AMP-activated protein kinase catalytic subunit alpha-10022
Adenosine deaminase-like protein0001
Protease 0112
P2Y purinoceptor 110011
Histamine H3 receptor0101
5'-AMP-activated protein kinase subunit gamma-30011
5'-AMP-activated protein kinase subunit gamma-20011
5'-AMP-activated protein kinase subunit beta-10022
ATP-dependent phosphofructokinase3003
TDP1 protein2002
pregnane X nuclear receptor6006
estrogen nuclear receptor alpha7007
peroxisome proliferator activated receptor gamma5005
cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a6006
15-hydroxyprostaglandin dehydrogenase [NAD(+)] isoform 12002
thyroid hormone receptor beta isoform 25005
nuclear receptor ROR-gamma isoform 13003
lamin isoform A-delta105005
Gamma-aminobutyric acid receptor subunit pi2204
Bromodomain-containing protein 40011
Gamma-aminobutyric acid receptor subunit alpha-10314
Gamma-aminobutyric acid receptor subunit beta-12204
Gamma-aminobutyric acid receptor subunit delta2204
Gamma-aminobutyric acid receptor subunit gamma-20303
Gamma-aminobutyric acid receptor subunit gamma-22204
Gamma-aminobutyric acid receptor subunit alpha-52204
Gamma-aminobutyric acid receptor subunit alpha-32204
Gamma-aminobutyric acid receptor subunit gamma-12204
Gamma-aminobutyric acid receptor subunit alpha-22204
Gamma-aminobutyric acid receptor subunit alpha-42204
Gamma-aminobutyric acid receptor subunit gamma-32204
Gamma-aminobutyric acid receptor subunit alpha-62204
Cholecystokinin receptor type A0202
Gamma-aminobutyric acid receptor subunit alpha-50314
Gamma-aminobutyric acid receptor subunit alpha-30314
Gamma-aminobutyric acid receptor subunit alpha-20314
Gamma-aminobutyric acid receptor subunit beta-20303
Gamma-aminobutyric acid receptor subunit alpha-12204
Gamma-aminobutyric acid receptor subunit beta-32204
Gamma-aminobutyric acid receptor subunit beta-22204
Cholecystokinin receptor type A0101
GABA theta subunit2204
ATPase family AAA domain-containing protein 53003
Ataxin-23003
Gamma-aminobutyric acid receptor subunit epsilon2204
Chain A, Cruzipain1001
SMAD family member 22002
SMAD family member 32002
GLI family zinc finger 35005
caspase 7, apoptosis-related cysteine protease2002
estrogen receptor 2 (ER beta)3003
nuclear receptor subfamily 1, group I, member 36006
retinoic acid nuclear receptor alpha variant 16006
retinoid X nuclear receptor alpha5005
peroxisome proliferator-activated receptor delta3003
vitamin D (1,25- dihydroxyvitamin D3) receptor2002
caspase-32002
Caspase-72002
vitamin D3 receptor isoform VDRA4004
thyroid hormone receptor beta isoform a5005
caspase-32002
nuclear factor erythroid 2-related factor 2 isoform 15005
geminin6006
Voltage-dependent calcium channel gamma-2 subunit4004
Solute carrier organic anion transporter family member 2B1 0001
3-hydroxy-3-methylglutaryl-coenzyme A reductase0202
Cellular tumor antigen p535005
ATP-dependent translocase ABCB10202
Insulin receptor 0101
Glutamate receptor 24004
Dipeptidyl peptidase 40101
Prostaglandin G/H synthase 20101
3-hydroxy-3-methylglutaryl-coenzyme A reductase 0101
Histone deacetylase 10303
Histone deacetylase 20303
Solute carrier organic anion transporter family member 1B30001
Histone deacetylase 60303
Broad substrate specificity ATP-binding cassette transporter ABCG20202
Solute carrier organic anion transporter family member 1B10102
Chain A, Glycogen Phosphorylase0101
Chain A, Glycogen phosphorylase, liver form0011
Chain A, glycogen phosphorylase, liver form0011
Chain A, Glycogen phosphorylase, liver form0011
Chain A, Glycogen phosphorylase, liver form0011
Chain A, Chitinase0101
phosphopantetheinyl transferase5005
GLS protein1001
farnesoid X nuclear receptor3003
thyroid stimulating hormone receptor2002
atrial natriuretic peptide receptor 1 precursor1001
chromobox protein homolog 14004
DNA polymerase beta1001
DNA polymerase kappa isoform 11001
muscarinic acetylcholine receptor M13003
lethal factor (plasmid)2002
ATP-binding cassette sub-family C member 30505
Multidrug resistance-associated protein 40505
Potassium channel subfamily K member 20011
Bile salt export pump0808
Glycogen phosphorylase, muscle form0101
Renin0101
Carbonic anhydrase 10202
Carbonic anhydrase 20202
Cholinesterase0707
Glycogen phosphorylase, liver form0101
Glycogen phosphorylase, muscle form0101
Replicase polyprotein 1ab0101
Adenosine receptor A30101
Replicase polyprotein 1ab0101
Amine oxidase [flavin-containing] A0202
Acetylcholinesterase07311
Adenosine receptor A10203
Amine oxidase [flavin-containing] B0303
cAMP-specific 3',5'-cyclic phosphodiesterase 4A0101
Adenosine receptor A30101
Adenosine receptor A2a0214
Adenosine receptor A2b0102
Adenosine receptor A2b0203
Adenosine receptor A2a0204
Vasopressin V2 receptor0001
Serine/threonine-protein kinase mTOR0101
Adenosine receptor A2a0101
Adenosine receptor A10101
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform 0101
DNA-dependent protein kinase catalytic subunit0101
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B0101
Adenylate cyclase type 10001
Chitotriosidase-10101
Serine-protein kinase ATM0101
Serine/threonine-protein kinase ATR0101
Adenosine receptor A2b0102
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C0101
Palmitoleoyl-protein carboxylesterase NOTUM0224
Endochitinase B10101
Muscarinic acetylcholine receptor0001
Canalicular multispecific organic anion transporter 10505
Phosphodiesterase 0101
Guanine deaminase0101
Ornithine decarboxylase0101
P2Y purinoceptor 120101
Chain A, TYROSYL-DNA PHOSPHODIESTERASE3003
Chain A, HADH2 protein2002
Chain B, HADH2 protein2002
Chain A, JmjC domain-containing histone demethylation protein 3A1001
acetylcholinesterase1001
15-lipoxygenase, partial1001
hypoxia-inducible factor 1 alpha subunit1001
USP1 protein, partial1001
Microtubule-associated protein tau1001
aldehyde dehydrogenase 1 family, member A13003
PINK11001
thyroid stimulating hormone receptor1001
progesterone receptor2002
Parkin1001
bromodomain adjacent to zinc finger domain 2B1001
aryl hydrocarbon receptor3003
activating transcription factor 61001
nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105), isoform CRA_a1001
Histone H2A.x1001
serine-protein kinase ATM isoform a1001
polyunsaturated fatty acid lipoxygenase ALOX121001
prostaglandin E2 receptor EP2 subtype0001
potassium voltage-gated channel subfamily H member 2 isoform d3003
heat shock protein beta-11001
mitogen-activated protein kinase 12002
serine/threonine-protein kinase PLK11001
lethal(3)malignant brain tumor-like protein 1 isoform I1001
cytochrome P450 3A4 isoform 12002
histone acetyltransferase KAT2A isoform 11001
Acetylcholinesterase 0101
Nuclear receptor ROR-gamma3003
Carboxylic ester hydrolase 0101
Rap guanine nucleotide exchange factor 41001
ORF730011
Gamma-aminobutyric acid receptor subunit pi0202
Gamma-aminobutyric acid receptor subunit delta0202
Gamma-aminobutyric acid receptor subunit alpha-10101
Gamma-aminobutyric acid receptor subunit beta-10101
Neuronal acetylcholine receptor subunit alpha-40101
Gamma-aminobutyric acid receptor subunit alpha-20101
Gamma-aminobutyric acid receptor subunit alpha-30101
Neuronal acetylcholine receptor subunit beta-20101
Gamma-aminobutyric acid receptor subunit beta-10202
Gamma-aminobutyric acid receptor subunit alpha-40101
Gamma-aminobutyric acid receptor subunit gamma-20101
Gamma-aminobutyric acid receptor subunit beta-30202
Translocator protein0101
Translocator protein0101
Gastrin/cholecystokinin type B receptor0101
Gamma-aminobutyric acid receptor subunit alpha-40202
Gamma-aminobutyric acid receptor subunit epsilon0202
Gamma-aminobutyric acid receptor subunit alpha-60202
Gamma-aminobutyric acid receptor subunit gamma-10202
Gamma-aminobutyric acid receptor subunit gamma-30202
Gamma-aminobutyric acid receptor subunit theta0202
peripheral myelin protein 222002
Acetylcholinesterase0505
Voltage-dependent L-type calcium channel subunit alpha-1F0101
Bile salt export pump0202
cGMP-specific 3',5'-cyclic phosphodiesterase0101
Acetylcholinesterase0404
Amyloid-beta precursor protein0101
Cytochrome P450 3A40303
5-hydroxytryptamine receptor 1A0101
Amine oxidase [flavin-containing] A 0202
Amine oxidase [flavin-containing] A 0101
Acetylcholinesterase0404
Liver carboxylesterase 10202
Acetylcholinesterase 0505
Sodium-dependent serotonin transporter0202
Choline O-acetyltransferase 0101
Acetylcholinesterase0303
Glycogen synthase kinase-3 beta0101
Beta-secretase 10202
Cholinesterase0516
Voltage-dependent L-type calcium channel subunit alpha-1D 0101
Cholinesterase0202
Acetylcholine receptor subunit epsilon0101
cAMP-specific 3',5'-cyclic phosphodiesterase 4D0101
Potassium voltage-gated channel subfamily H member 20202
Voltage-dependent L-type calcium channel subunit alpha-1S0101
Voltage-dependent L-type calcium channel subunit alpha-1C0202
Cytochrome P450 1B10202
Sigma non-opioid intracellular receptor 10202
Acyl-CoA:cholesterol acyltransferase 0101
Sigma non-opioid intracellular receptor 10101
Carboxylic ester hydrolase 0202
Carboxylic ester hydrolase 0606
Histamine H3 receptor0202
Chain A, ACETYLCHOLINESTERASE0101
Chain A, Acetylcholinesterase0101
Vascular endothelial growth factor receptor 1 0101
Delta-type opioid receptor0202
Vascular endothelial growth factor receptor 30101
Vascular endothelial growth factor receptor 20101
Kappa-type opioid receptor0101
Prolyl endopeptidase0101
Small conductance calcium-activated potassium channel protein 30101
Solute carrier family 22 member 1 0101
Mu-type opioid receptor0101
Kappa-type opioid receptor0101
Mas-related G-protein coupled receptor member X20011
Chain A, MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASE1001
thioredoxin reductase2002
GALC protein1001
EWS/FLI fusion protein4004
cytochrome P450 2D61001
Bloom syndrome protein isoform 12002
cytochrome P450 2D6 isoform 12002
peripheral myelin protein 22 isoform 12002
D(1A) dopamine receptor1001
nuclear factor erythroid 2-related factor 2 isoform 21001
Sodium channel protein type 1 subunit alpha0101
Sodium channel protein type 2 subunit alpha0101
Sodium channel protein type 3 subunit alpha0101
Dihydrofolate reductase0202
Potassium voltage-gated channel subfamily E member 10101
Sodium channel protein type 4 subunit alpha0102
Potassium voltage-gated channel subfamily KQT member 10101
Sodium channel protein type 5 subunit alpha0101
Sodium channel protein type 9 subunit alpha0101
Sodium channel protein type 2 subunit alpha0101
Sodium channel protein type 3 subunit alpha0101
Sigma non-opioid intracellular receptor 10101
Sodium channel protein type 10 subunit alpha0101
chaperonin-containing TCP-1 beta subunit homolog1001
flap endonuclease 11001
Synaptic vesicle glycoprotein 2A0101
Chain A, 2-oxoglutarate Oxygenase1001
interleukin 81001
ClpP1001
ATAD5 protein, partial1001
ras-related protein Rab-9A1001
M-phase phosphoprotein 81001
Cytochrome P450 1A10101
Cytochrome P450 1A2 0101
Myeloperoxidase0101
Cytochrome P450 1A20101
Cytochrome P450 2C11 0101
Cytochrome P450 2D60101
Aromatase0101
Ribosyldihydronicotinamide dehydrogenase [quinone]0202
Metabotropic glutamate receptor 10101
Mu-type opioid receptor0202
Nociceptin receptor0101
Alpha-1A adrenergic receptor0101
Melatonin receptor type 1A0213
Melatonin receptor type 1C0011
Melatonin receptor type 1A0112
Melatonin receptor type 1B0213
Melatonin receptor type 1C0112
Melatonin receptor type 1B0112
Nuclear factor erythroid 2-related factor 20001
Chain A, Beta-lactamase1001
Chain A, Ferritin light chain1001
glp-1 receptor, partial1001
pregnane X receptor2002
nonstructural protein 11001
heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)1001
heat shock protein HSP 90-alpha isoform 20001
DNA polymerase iota isoform a (long)1001
Polyunsaturated fatty acid lipoxygenase ALOX15B1001
Histamine H2 receptor1001
Guanine nucleotide-binding protein G1001
TAR DNA-binding protein 431001
heat shock protein 90, putative0001
Acyl-CoA desaturase 10101
Acetylcholine receptor subunit epsilon0101
Sodium-dependent serotonin transporter0101
Cholinesterase0101
Tyrosine-protein kinase SYK0101
Sphingosine kinase 20202
Sphingosine kinase 10101
Carbonic anhydrase 0101
Carbonic anhydrase 40101
Carbonic anhydrase 5A, mitochondrial0101
Carbonic anhydrase0101
Carbonic anhydrase 90101
Carbonic anhydrase 0101
Carbonic anhydrase 5B, mitochondrial0101
Chain A, PLASMINOGEN0011
Chain A, PLASMINOGEN0011
Plasminogen0213
Urokinase-type plasminogen activator0101
Luciferase1001
Cocaine esterase0101
Histone deacetylase 30202
UDP-glucuronosyltransferase 1A90001
Aldo-keto reductase family 1 member B10101
Cytochrome P450 2A60101
Tissue factor0101
Aldo-keto reductase family 1 member A10101
UDP-glucuronosyltransferase 2B70102
UDP-glucuronosyltransferase 1-60001
Aldo-keto reductase family 1 member A10101
Histone deacetylase 40202
Aldo-keto reductase family 1 member A10101
Aldo-keto reductase family 1 member B70101
Histone deacetylase 70202
Polyamine deacetylase HDAC100202
Histone deacetylase 11 0202
Histone deacetylase 80202
NAD-dependent protein deacylase sirtuin-5, mitochondrial0101
Histone deacetylase 90202
Histone deacetylase 50202
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]