Page last updated: 2024-09-27

Accessory Atrioventricular Bundle

Extra impulse-conducting tissue in the heart that creates abnormal impulse-conducting connections between HEART ATRIA and HEART VENTRICLES.

Synonyms(18)

Synonym
Accessory Atrioventricular Pathways
Bundle of Kent
Accessory Conducting Pathway
Atriohisian Tract
Atriohisian Fibers
Accessory Conducting Pathways
Nodoventricular Pathway
Nodoventricular Accessory Pathway
Accessory Atrioventricular Pathway
Kent Bundle
Fasciculoventricular Accessory Pathway
James Fibers
Atrio-Hisian Bypass Tract
Mahaim Fiber
Concealed Accessory Pathway
Mahaim Fibers
Accessory Atrioventricular Bundle
Fasciculoventricular Pathway

Research Excerpts

Research

Studies (38)

TimeframeStudies, This Condition (%)All Conditions %
pre-19900 (0.00)23.3326
1990's0 (0.00)12.5806
2000's0 (0.00)18.1394
2010's33 (86.84)28.8240
2020's5 (13.16)9.53
DrugIndicatedRelationship StrengthStudiesTrials
antazoline0low10
verapamil0low10
flecainide0low20
ethidium0low10
isoproterenol0low70
propofol0low20
risperidone0low10
sevoflurane0low10
adenosine0medium181
nifekalant hydrochloride0low10
dihydroethidium0low10
atropine0low10
digoxin0low10
4-hydroxy-2-nonenal0low10
ubiquinone0low10
technetium tc 99m sestamibi0medium11
natriuretic peptide, brain0low20
pyrimidinones0low10

Protein Targets (453)

ProteinPotency MeasurementsInhibition MeasurementsActivation MeasurementsDrugs
Microtubule-associated protein tau3003
vitamin D3 receptor isoform VDRA3003
Transient receptor potential cation channel subfamily A member 10011
Chain A, MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASE4004
Chain A, Membrane lipoprotein tmpC0011
Chain A, Membrane lipoprotein tmpC0011
Chain A, Membrane lipoprotein tmpC0011
Chain A, Structure of PAE2307 in complex with adenosine0011
Chain B, Structure of PAE2307 in complex with adenosine0011
Chain A, ADENOSINE RECEPTOR A2A0101
Chain A, ADENOSINE RECEPTOR A2A0101
Chain A, tRNA (guanine-N(1)-)-methyltransferase0011
Chain A, Uncharacterized protein MJ08830011
AR protein6006
signal transducer and activator of transcription 6, interleukin-4 induced1001
regulator of G-protein signaling 45005
glucocorticoid receptor [Homo sapiens]6006
retinoid X nuclear receptor alpha4004
estrogen nuclear receptor alpha8008
NPYLR7B0022
arylsulfatase A1001
IDH12002
Histone H2A.x3003
glycogen synthase kinase-3 beta isoform 10011
mitogen-activated protein kinase 11001
flap endonuclease 12002
nuclear receptor ROR-gamma isoform 13003
peripheral myelin protein 223003
survival motor neuron protein isoform d2002
high affinity choline transporter 1 isoform a0101
Sodium/nucleoside cotransporter 10202
Calcium dependent protein kinase0101
Mitogen-activated protein kinase kinase kinase 70011
Sodium/nucleoside cotransporter 20202
Voltage-dependent calcium channel gamma-2 subunit3003
Rap guanine nucleotide exchange factor 31001
Purine nucleoside phosphorylase0101
Epidermal growth factor receptor0101
Phosphoglycerate kinase 1 0101
Adenosine deaminase0001
Avidin0011
Adenosine deaminase0001
Glyceraldehyde-3-phosphate dehydrogenase0202
Receptor tyrosine-protein kinase erbB-20101
Insulin receptor0001
Phosphoglycerate kinase 20101
Heat shock protein HSP 90-alpha0112
Platelet-derived growth factor receptor beta0001
Adenosine receptor A30225
Heat shock 70 kDa protein 1A 0101
Heat shock cognate 71 kDa protein0011
Fibroblast growth factor receptor 10001
Inosine-5'-monophosphate dehydrogenase 20101
Endoplasmin0112
Glutamate receptor 23003
Inosine-5'-monophosphate dehydrogenase 1 0101
Fibroblast growth factor receptor 20001
Fibroblast growth factor receptor 40001
Fibroblast growth factor receptor 30001
Streptavidin0011
Adenosylhomocysteinase0001
Adenosine receptor A10112
Adenosine receptor A30101
Adenosine receptor A2a0124
Adenosine receptor A2b0012
Adenosine receptor A2b0112
Adenylate kinase 2, mitochondrial0101
Adenosine receptor A10225
Adenosine receptor A2a0112
Adenylate kinase isoenzyme 1 0101
Phosphatidylinositol 4-kinase alpha0203
Adenosine receptor A10011
Adenosine kinase0001
Adenosine deaminase 0001
Equilibrative nucleoside transporter 20202
Phosphatidylinositol 4-kinase type 2-beta0203
Histone-lysine N-methyltransferase, H3 lysine-79 specific0101
Equilibrative nucleoside transporter 10202
Phosphatidylinositol 4-kinase type 2-alpha0203
Solute carrier family 28 member 30202
Adenosine kinase0102
Phosphatidylinositol 4-kinase beta0203
5-methylthioadenosine/S-adenosylhomocysteine deaminase0001
Adenosine transporter 10001
USP1 protein, partial2002
TDP1 protein8008
thyroid stimulating hormone receptor4004
cytochrome P450 2D6 isoform 12002
histone-lysine N-methyltransferase 2A isoform 2 precursor1001
lethal factor (plasmid)2002
lamin isoform A-delta106006
Bile salt export pump0808
Histamine H1 receptor0112
Inositol monophosphatase 11001
Chain A, 2-oxoglutarate Oxygenase1001
GLI family zinc finger 35005
nuclear receptor subfamily 1, group I, member 34004
pregnane X nuclear receptor5005
cystic fibrosis transmembrane conductance regulator0101
DNA polymerase beta1001
short transient receptor potential channel 6 isoform 10011
Solute carrier family 22 member 1 0404
ATP-binding cassette sub-family C member 30404
Multidrug resistance-associated protein 40404
5-hydroxytryptamine receptor 40808
Muscarinic acetylcholine receptor M20317
Muscarinic acetylcholine receptor M40316
Muscarinic acetylcholine receptor M10215
Muscarinic acetylcholine receptor M30215
Muscarinic acetylcholine receptor M40215
Muscarinic acetylcholine receptor M50215
Muscarinic acetylcholine receptor M50316
Muscarinic acetylcholine receptor M20216
Muscarinic acetylcholine receptor M10317
Muscarinic acetylcholine receptor M10001
Muscarinic acetylcholine receptor M30417
Alpha-1D adrenergic receptor0415
5-hydroxytryptamine receptor 2C0808
Muscarinic acetylcholine receptor M40101
Histamine H2 receptor1013
5-hydroxytryptamine receptor 70303
Reverse transcriptase/RNaseH 0102
Muscarinic acetylcholine receptor0112
Canalicular multispecific organic anion transporter 10404
Chain A, Beta-lactamase1001
Chain A, ATP-DEPENDENT DNA HELICASE Q12002
Chain A, Cruzipain1001
interleukin 81001
PAX80001
RAR-related orphan receptor gamma2002
SMAD family member 21001
ATAD5 protein, partial1001
PPM1D protein1001
SMAD family member 31001
STAT3, partial0101
thioredoxin glutathione reductase1001
Smad33003
estrogen receptor 2 (ER beta)2002
progesterone receptor3003
retinoic acid nuclear receptor alpha variant 12002
estrogen-related nuclear receptor alpha5005
farnesoid X nuclear receptor2002
67.9K protein2002
peroxisome proliferator-activated receptor delta2002
peroxisome proliferator activated receptor gamma2002
vitamin D (1,25- dihydroxyvitamin D3) receptor2002
alpha-galactosidase1001
cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a2002
thyroid stimulating hormone receptor4004
activating transcription factor 64004
nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105), isoform CRA_a2002
v-jun sarcoma virus 17 oncogene homolog (avian)2002
NPC intracellular cholesterol transporter 1 precursor1001
cellular tumor antigen p53 isoform a1001
tumor necrosis factor1001
thyroid hormone receptor beta isoform a2002
nuclear factor erythroid 2-related factor 2 isoform 21001
parathyroid hormone/parathyroid hormone-related peptide receptor precursor2002
thyroid hormone receptor beta isoform 25005
ras-related protein Rab-9A1001
nuclear factor erythroid 2-related factor 2 isoform 13003
signal transducer and activator of transcription 1-alpha/beta isoform alpha0101
geminin3003
Solute carrier organic anion transporter family member 1A40102
Interferon beta3003
Cellular tumor antigen p533003
Sodium/potassium-transporting ATPase subunit alpha-1 0202
Sodium/potassium-transporting ATPase subunit beta-10202
Integrin beta-31001
Sodium/potassium-transporting ATPase subunit alpha-20101
Sodium/potassium-transporting ATPase subunit alpha-3 0101
ATP-dependent translocase ABCB10202
Sodium/potassium-transporting ATPase subunit beta-1 0101
ATP-dependent translocase ABCB104114
Integrin alpha-IIb1001
Cytochrome P450 3A40506
Replicase polyprotein 1ab0101
Sodium/potassium-transporting ATPase subunit alpha-30101
Sodium/potassium-transporting ATPase subunit beta-20101
ATP-dependent translocase ABCB10203
Sodium/potassium-transporting ATPase subunit alpha-20202
Sodium/potassium-transporting ATPase subunit alpha-10101
Nuclear receptor ROR-gamma1113
Sodium/potassium-transporting ATPase subunit beta-30101
Sodium/potassium-transporting ATPase subunit gamma0101
Sodium/potassium-transporting ATPase subunit alpha-40101
Sodium/potassium-transporting ATPase subunit alpha-40101
Solute carrier organic anion transporter family member 4C10001
Solute carrier organic anion transporter family member 4C10001
ATPase family AAA domain-containing protein 51001
Ataxin-22002
Solute carrier organic anion transporter family member 1A40001
Solute carrier organic anion transporter family member 1B30101
Solute carrier organic anion transporter family member 1B10303
Chain A, HTH-type transcriptional regulator qacR0011
Chain B, HTH-type transcriptional regulator qacR0011
Chain A, PROBABLE TRANSCRIPTIONAL REGULATORY PROTEIN (PROBABLY DEOR-FAMILY)0011
Chain B, PROBABLE TRANSCRIPTIONAL REGULATORY PROTEIN (PROBABLY DEOR-FAMILY)0011
thioredoxin reductase4004
GLS protein3003
cytochrome P450 family 3 subfamily A polypeptide 45005
cytochrome P450 2D65005
glucocerebrosidase2002
euchromatic histone-lysine N-methyltransferase 25005
D(1A) dopamine receptor2002
huntingtin isoform 22002
cytochrome P450 3A4 isoform 12002
histone acetyltransferase KAT2A isoform 12002
Gamma-aminobutyric acid receptor subunit pi2114
Polyunsaturated fatty acid lipoxygenase ALOX15B1001
Voltage-dependent L-type calcium channel subunit alpha-1C0202
Voltage-dependent L-type calcium channel subunit alpha-1F0404
Cytochrome P450 2C9 0303
Gamma-aminobutyric acid receptor subunit beta-12114
Gamma-aminobutyric acid receptor subunit delta2114
Gamma-aminobutyric acid receptor subunit gamma-22114
Gamma-aminobutyric acid receptor subunit alpha-52114
Gamma-aminobutyric acid receptor subunit alpha-32114
Voltage-dependent L-type calcium channel subunit alpha-1C0202
Gamma-aminobutyric acid receptor subunit gamma-12114
Gamma-aminobutyric acid receptor subunit alpha-22114
Voltage-dependent L-type calcium channel subunit alpha-1D0202
Gamma-aminobutyric acid receptor subunit alpha-42114
Gamma-aminobutyric acid receptor subunit gamma-32114
Gamma-aminobutyric acid receptor subunit alpha-62114
Sodium channel protein type 1 subunit alpha0101
Sodium channel protein type 4 subunit alpha0101
Cytochrome P450 2J20303
Spike glycoprotein4004
Gamma-aminobutyric acid receptor subunit alpha-12114
Gamma-aminobutyric acid receptor subunit beta-32114
Gamma-aminobutyric acid receptor subunit beta-22114
Sodium channel protein type 7 subunit alpha0101
Voltage-dependent L-type calcium channel subunit alpha-1D 0404
Voltage-dependent L-type calcium channel subunit alpha-1S0202
Potassium voltage-gated channel subfamily A member 10202
Potassium voltage-gated channel subfamily H member 20505
Voltage-dependent L-type calcium channel subunit alpha-1S0404
Voltage-dependent L-type calcium channel subunit alpha-1C0404
Sodium channel protein type 5 subunit alpha0404
Sodium channel protein type 9 subunit alpha0101
GABA theta subunit2114
Sodium channel protein type 2 subunit alpha0101
Gamma-aminobutyric acid receptor subunit epsilon2114
Sodium channel protein type 3 subunit alpha0101
Sodium channel protein type 11 subunit alpha0101
Broad substrate specificity ATP-binding cassette transporter ABCG20213
Sodium channel protein type 8 subunit alpha0101
Sodium channel protein type 10 subunit alpha0101
Chain A, Putative fructose-1,6-bisphosphate aldolase1001
aldehyde dehydrogenase 1 family, member A11001
Bloom syndrome protein isoform 12002
DNA polymerase iota isoform a (long)2002
DNA polymerase kappa isoform 11001
EWS/FLI fusion protein4004
potassium voltage-gated channel subfamily H member 2 isoform d4004
Potassium voltage-gated channel subfamily A member 50101
Potassium voltage-gated channel subfamily D member 20101
glp-1 receptor, partial2002
phosphopantetheinyl transferase1001
Beta-1 adrenergic receptor 0012
beta-2 adrenergic receptor1001
hexokinase-4 isoform 11001
chromobox protein homolog 11001
glucokinase regulatory protein1001
serine/threonine-protein kinase mTOR isoform 11001
Bile salt export pump0202
Beta-2 adrenergic receptor0225
Beta-1 adrenergic receptor0213
Beta-2 adrenergic receptor0213
Polyunsaturated fatty acid lipoxygenase ALOX150202
Beta-3 adrenergic receptor0112
D(2) dopamine receptor0303
Alpha-1B adrenergic receptor0303
Beta-1 adrenergic receptor0315
Beta-2 adrenergic receptor0011
Alpha-2B adrenergic receptor0303
D(1A) dopamine receptor0303
D(4) dopamine receptor0202
Alpha-2C adrenergic receptor0303
Alpha-2A adrenergic receptor0303
Alpha-1D adrenergic receptor0303
Beta-adrenergic receptor kinase 10011
Beta-3 adrenergic receptor0011
Beta-3 adrenergic receptor0112
Vasopressin V1a receptor0011
Beta-1 adrenergic receptor0112
Alpha-1A adrenergic receptor0213
Alpha-1B adrenergic receptor0112
Glutamate receptor ionotropic, NMDA 1 0011
D(3) dopamine receptor0505
Alpha-1A adrenergic receptor0303
D(1A) dopamine receptor1001
Beta-2 adrenergic receptor0101
Taste receptor type 2 member 380011
Taste receptor type 2 member 390011
Taste receptor type 2 member 400011
Taste receptor type 2 member 410011
Taste receptor type 2 member 430011
Taste receptor type 2 member 310011
Taste receptor type 2 member 450011
Taste receptor type 2 member 460011
Taste receptor type 2 member 300011
Taste receptor type 2 member 190011
Taste receptor type 2 member 200011
Taste receptor type 2 member 500011
Taste receptor type 2 member 600011
Oxytocin receptor0011
Glutamate receptor ionotropic, NMDA 2A 0011
Glutamate receptor ionotropic, NMDA 2B0011
Glutamate receptor ionotropic, NMDA 2C0011
Beta-2 adrenergic receptor 0112
Glutamate receptor ionotropic, NMDA 2D0011
Taste receptor type 2 member 420011
Beta-2 adrenergic receptor0022
Glutamate receptor ionotropic, NMDA 3B0011
Taste receptor type 2 member 160011
Taste receptor type 2 member 140011
Taste receptor type 2 member 130011
Taste receptor type 2 member 100011
Taste receptor type 2 member 90011
Taste receptor type 2 member 80011
Taste receptor type 2 member 70011
Taste receptor type 2 member 50011
Taste receptor type 2 member 40011
Taste receptor type 2 member 30011
Taste receptor type 2 member 10011
Glutamate receptor ionotropic, NMDA 3A0011
2,3-bisphosphoglycerate-independent phosphoglycerate mutase1001
ATP-dependent phosphofructokinase1001
Atrial natriuretic peptide receptor 10101
apical membrane antigen 1, AMA11001
Chain A, Ferritin light chain1001
Chain A, Ferritin light chain0011
Chain A, Ferritin light chain0011
Chain A, Ferritin light chain0011
Chain A, Ferritin light chain0011
Chain A, Ferritin light chain0011
Chain A, Ferritin light chain0011
Chain A, Ferritin light chain0011
caspase 7, apoptosis-related cysteine protease1001
hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)1001
G2002
caspase-31001
15-hydroxyprostaglandin dehydrogenase [NAD(+)] isoform 11001
heat shock protein beta-11001
muscarinic acetylcholine receptor M12002
Fatty-acid amide hydrolase 10101
UDP-glucuronosyltransferase 1A90001
Carbonic anhydrase 10101
Carbonic anhydrase 20101
HLA class I histocompatibility antigen, B alpha chain 2002
Aldo-keto reductase family 1 member B10202
Gamma-aminobutyric acid receptor subunit alpha-10001
Gamma-aminobutyric acid receptor subunit beta-10001
Gamma-aminobutyric acid receptor subunit alpha-20001
Gamma-aminobutyric acid receptor subunit alpha-30001
Gamma-aminobutyric acid receptor subunit alpha-10112
Gamma-aminobutyric acid receptor subunit beta-10011
Gamma-aminobutyric acid receptor subunit gamma-20112
Gamma-aminobutyric acid receptor subunit alpha-40001
Gamma-aminobutyric acid receptor subunit gamma-20001
Prostaglandin G/H synthase 10101
Sodium-dependent noradrenaline transporter 0202
Sodium- and chloride-dependent GABA transporter 10101
Gamma-aminobutyric acid receptor subunit beta-30112
Gamma-aminobutyric acid receptor subunit alpha-50011
Sodium- and chloride-dependent GABA transporter 20101
Sodium- and chloride-dependent GABA transporter 30101
Gamma-aminobutyric acid receptor subunit alpha-30011
5-hydroxytryptamine receptor 2B0606
Gamma-aminobutyric acid receptor subunit alpha-20011
Gamma-aminobutyric acid receptor subunit beta-20011
Sodium- and chloride-dependent betaine transporter0101
Gamma-aminobutyric acid receptor subunit alpha-40011
Fatty-acid amide hydrolase 10101
Gamma-aminobutyric acid receptor subunit alpha-60011
Inositol hexakisphosphate kinase 12002
UDP-glucuronosyltransferase 1A80001
cytochrome P450 2C9, partial2002
Chain A, JmjC domain-containing histone demethylation protein 3A1001
acetylcholinesterase1001
peripheral myelin protein 22 isoform 11001
cytochrome P450 2C19 precursor1001
transcriptional regulator ERG isoform 31001
Solute carrier family 22 member 20101
Albumin0011
5-hydroxytryptamine receptor 1A0123
5-hydroxytryptamine receptor 2C0202
Alpha-2A adrenergic receptor0404
Cytochrome P450 2D60101
Angiotensin-converting enzyme0202
5-hydroxytryptamine receptor 2A0202
Alpha-2B adrenergic receptor0202
Alpha-2C adrenergic receptor0202
D0101
D(3) dopamine receptor0101
5-hydroxytryptamine receptor 1A0404
Glycine receptor subunit alpha-10011
Sodium-dependent dopamine transporter0101
Histamine H2 receptor0404
5-hydroxytryptamine receptor 2A0404
5-hydroxytryptamine receptor 1B0404
5-hydroxytryptamine receptor 2B0202
Sodium-dependent serotonin transporter0404
5-hydroxytryptamine receptor 7 0101
5-hydroxytryptamine receptor 2C 0101
5-hydroxytryptamine receptor 70101
5-hydroxytryptamine receptor 2A0101
Histamine H1 receptor0202
5-hydroxytryptamine receptor 60101
3-hydroxy-3-methylglutaryl-coenzyme A reductase 0101
D(2) dopamine receptor0101
D(2) dopamine receptor0303
5-hydroxytryptamine receptor 2B0101
Transporter0101
5-hydroxytryptamine receptor 1A0101
Nuclear receptor subfamily 3 group C member 3 0202
Multidrug and toxin extrusion protein 20101
Multidrug and toxin extrusion protein 10101
Transporter0101
Histamine H3 receptor0101
Acetylcholinesterase0101
Acetylcholinesterase0101
Cholinesterase0101
Acyl-CoA desaturase 10101
Acetylcholine receptor subunit epsilon0101
Amine oxidase [flavin-containing] B0101
Amine oxidase [flavin-containing] A 0101
Acetylcholinesterase0202
Acetylcholinesterase0101
Acetylcholinesterase 0101
Sodium-dependent serotonin transporter0101
Delta-type opioid receptor0202
Cholinesterase0101
Acetylcholinesterase0101
Tyrosine-protein kinase SYK0101
Beta-secretase 10101
Cholinesterase0112
Cholinesterase0101
Carboxylic ester hydrolase 0101
Carboxylic ester hydrolase 0101
lysosomal alpha-glucosidase preproprotein1001
Albumin0011
Glycoprotein0101
Muscarinic acetylcholine receptor M20011
Cytochrome P450 2C80101
Catechol O-methyltransferase0101
Potassium voltage-gated channel subfamily A member 30101
Multidrug resistance-associated protein 1 0214
Mu-type opioid receptor0101
Kappa-type opioid receptor0101
Chloroquine resistance transporter0101
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]