Page last updated: 2024-09-28

Accelerated Idioventricular Rhythm

A type of automatic, not reentrant, ectopic ventricular rhythm with episodes lasting from a few seconds to a minute which usually occurs in patients with acute myocardial infarction or with DIGITALIS toxicity. The ventricular rate is faster than normal but slower than tachycardia, with an upper limit of 100 -120 beats per minute. Suppressive therapy is rarely necessary.

Synonyms(3)

Synonym
Slow Ventricular Tachycardia
Accelerated Idioventricular Rhythm
AIVR

Research Excerpts

Context

ExcerptReference
"Accelerated idioventricular rhythm has been documented in several cases involving the induction of general anesthesia; however, it has not previously been known to occur during reversal of neuromuscular blockade with neostigmine and glycopyrrolate."( Bartlett, HL; Rizner, JD; Shaw, RE, 2022)

Treatment

ExcerptReference
"Herein, we report a patient with accelerated idioventricular rhythm (AIVR) due to hyperkalemia, which was successfully treated with glucose-insulin (GI) infusion."( Erdogan, HI; Gul, EE; Nikus, KC; Soylu, A; Yıldırım, O, 2012)

Research

Studies (20)

TimeframeStudies, This Condition (%)All Conditions %
pre-19900 (0.00)23.3326
1990's3 (15.00)12.5806
2000's4 (20.00)18.1394
2010's9 (45.00)28.8240
2020's4 (20.00)9.53
DrugIndicatedRelationship StrengthStudiesTrials
glycine0low10
amiodarone0low30
verapamil0low10
lidocaine0low10
isoflurane0low10
isoproterenol0low10
ketamine0low10
methylphenidate0low10
neostigmine0low10
ofloxacin0low10
procainamide0low10
propofol0low10
propranolol0low10
xylazine0low10
tyrosine0low10
thiophenes0low10
1,4-butanediol0low10
glycopyrrolate0low10
timolol0low10
tirofiban0low10
levofloxacin0low10
dorzolamide0low10
sodium oxybate0low10
tridihexethyl0low10
jesaconitine0low10
aconitine0low10

Protein Targets (474)

ProteinPotency MeasurementsInhibition MeasurementsActivation MeasurementsDrugs
USP1 protein, partial3003
GLI family zinc finger 35005
estrogen receptor 2 (ER beta)2002
retinoic acid nuclear receptor alpha variant 15005
thyroid hormone receptor beta isoform 24004
Chain A, TYROSYL-DNA PHOSPHODIESTERASE2002
acetylcholinesterase1001
phosphopantetheinyl transferase2002
hypoxia-inducible factor 1 alpha subunit1001
RAR-related orphan receptor gamma3003
SMAD family member 22002
ATAD5 protein, partial1001
Fumarate hydratase1001
NFKB1 protein, partial2002
PPM1D protein1001
SMAD family member 32002
TDP1 protein100010
Thrombopoietin1001
AR protein6006
caspase 7, apoptosis-related cysteine protease2002
aldehyde dehydrogenase 1 family, member A15005
hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)2002
thyroid stimulating hormone receptor4004
nuclear receptor subfamily 1, group I, member 33003
progesterone receptor3003
EWS/FLI fusion protein5005
glucocorticoid receptor [Homo sapiens]4004
retinoid X nuclear receptor alpha1001
estrogen-related nuclear receptor alpha3003
farnesoid X nuclear receptor2002
pregnane X nuclear receptor4004
estrogen nuclear receptor alpha8008
G3003
cytochrome P450 2D65005
polyprotein1001
peroxisome proliferator-activated receptor delta1001
peroxisome proliferator activated receptor gamma2002
caspase-32002
euchromatic histone-lysine N-methyltransferase 2100010
thyroid stimulating hormone receptor3003
v-jun sarcoma virus 17 oncogene homolog (avian)2002
Histone H2A.x3003
cytochrome P450 2D6 isoform 13003
cellular tumor antigen p53 isoform a1001
cytochrome P450 2C9 precursor1001
D(1A) dopamine receptor3003
chromobox protein homolog 15005
thyroid hormone receptor beta isoform a1001
potassium voltage-gated channel subfamily H member 2 isoform d2002
heat shock protein beta-12002
huntingtin isoform 22002
mitogen-activated protein kinase 13003
flap endonuclease 14004
serine/threonine-protein kinase mTOR isoform 12002
nuclear factor erythroid 2-related factor 2 isoform 13003
peptidyl-prolyl cis-trans isomerase NIMA-interacting 12002
urokinase-type plasminogen activator precursor1001
plasminogen precursor1001
urokinase plasminogen activator surface receptor precursor1001
nuclear receptor ROR-gamma isoform 12002
geminin5005
peripheral myelin protein 222002
survival motor neuron protein isoform d1001
cytochrome P450 3A4 isoform 15005
muscarinic acetylcholine receptor M17007
lethal factor (plasmid)1001
lamin isoform A-delta109009
Gamma-aminobutyric acid receptor subunit pi53311
Polyunsaturated fatty acid lipoxygenase ALOX15B1001
ATP-binding cassette sub-family C member 3010010
Multidrug resistance-associated protein 4010010
Voltage-dependent L-type calcium channel subunit alpha-1C0303
Solute carrier organic anion transporter family member 1A40101
Voltage-dependent L-type calcium channel subunit alpha-1F0303
5-hydroxytryptamine receptor 40808
Lysine-specific demethylase PHF20101
Bile salt export pump012012
Interferon beta3003
HLA class I histocompatibility antigen, B alpha chain 3003
Thyroid hormone receptor alpha0101
Receptor tyrosine-protein kinase erbB-20101
Cellular tumor antigen p535005
Integrin beta-31114
Tyrosine-protein kinase Fyn0101
ATP-dependent translocase ABCB10202
Aldo-keto reductase family 1 member B10404
Muscarinic acetylcholine receptor M20516
Muscarinic acetylcholine receptor M40303
ATP-dependent translocase ABCB106216
Integrin alpha-IIb1114
Beta-1 adrenergic receptor08210
Muscarinic acetylcholine receptor M50303
Alpha-2A adrenergic receptor0528
Adenosine receptor A30314
Cytochrome P450 2C80303
Thyroid hormone receptor alpha0101
Thyroid hormone receptor beta0101
Muscarinic acetylcholine receptor M10415
Beta-3 adrenergic receptor0729
D(2) dopamine receptor0415
Androgen receptor0303
Gamma-aminobutyric acid receptor subunit beta-153311
Alpha-1B adrenergic receptor0516
Lethal factor0101
Alpha-2B adrenergic receptor0214
Thyroid hormone receptor beta0101
Gamma-aminobutyric acid receptor subunit delta53311
Gamma-aminobutyric acid receptor subunit gamma-253311
Gamma-aminobutyric acid receptor subunit alpha-553311
Gamma-aminobutyric acid receptor subunit alpha-353311
Muscarinic acetylcholine receptor M30516
ATP-dependent translocase ABCB10203
Substance-K receptor0202
D(1A) dopamine receptor0415
D(4) dopamine receptor0303
Gamma-aminobutyric acid receptor subunit gamma-153311
Gamma-aminobutyric acid receptor subunit alpha-253311
Carnitine O-palmitoyltransferase 2, mitochondrial0101
Sodium-dependent noradrenaline transporter 0606
Histamine H2 receptor0404
Endothelin-1 receptor0314
5-hydroxytryptamine receptor 2A0617
5-hydroxytryptamine receptor 2C0819
Gamma-aminobutyric acid receptor subunit alpha-453311
Gamma-aminobutyric acid receptor subunit gamma-353311
Lysine-specific demethylase 5A0101
Gamma-aminobutyric acid receptor subunit alpha-653311
B2 bradykinin receptor0202
Sodium-dependent serotonin transporter0808
Melanocortin receptor 40202
C-8 sterol isomerase0101
Melanocortin receptor 50202
Mu-type opioid receptor0314
D(3) dopamine receptor0505
Sodium channel protein type 1 subunit alpha0101
Sodium channel protein type 4 subunit alpha0303
Squalene synthase0101
Delta-type opioid receptor0314
Kappa-type opioid receptor0314
5-hydroxytryptamine receptor 2B0819
C-C chemokine receptor type 20202
Melanocortin receptor 30202
Alpha-1A adrenergic receptor0516
Histamine H2 receptor1012
D(1A) dopamine receptor2002
5-hydroxytryptamine receptor 60415
Carnitine O-palmitoyltransferase 1, liver isoform0101
C-C chemokine receptor type 40202
Spike glycoprotein4004
Gamma-aminobutyric acid receptor subunit alpha-153311
Gamma-aminobutyric acid receptor subunit beta-353311
Gamma-aminobutyric acid receptor subunit beta-253311
Sodium channel protein type 7 subunit alpha0101
Voltage-dependent L-type calcium channel subunit alpha-1D 0303
Sodium-dependent dopamine transporter 0404
Potassium voltage-gated channel subfamily H member 20808
Voltage-dependent L-type calcium channel subunit alpha-1S0303
Voltage-dependent L-type calcium channel subunit alpha-1C0505
Sodium channel protein type 5 subunit alpha0404
Squalene monooxygenase0101
3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase0101
Sodium channel protein type 9 subunit alpha0202
Lysine-specific demethylase 7A0101
GABA theta subunit53311
Carnitine O-palmitoyltransferase 1, muscle isoform0101
Inositol hexakisphosphate kinase 13003
Canalicular multispecific organic anion transporter 1010010
Sodium channel protein type 2 subunit alpha0101
Ataxin-23003
Sigma non-opioid intracellular receptor 10404
Gamma-aminobutyric acid receptor subunit epsilon53311
NAD-dependent protein deacetylase sirtuin-3, mitochondrial0011
Sodium channel protein type 3 subunit alpha0202
Sodium channel protein type 11 subunit alpha0101
Histone lysine demethylase PHF80101
Sodium channel protein type 8 subunit alpha0101
Sodium channel protein type 10 subunit alpha0101
cytochrome P450 2C9, partial3003
ATP-dependent phosphofructokinase3003
Chain A, CARBONIC ANHYDRASE II0101
Chain A, CARBONIC ANHYDRASE II0101
Chain A, CARBONIC ANHYDRASE II0101
Carbonic anhydrase 0001
Carbonic anhydrase 0101
Carbonic anhydrase 0101
Carbonic anhydrase 0101
Carbonic anhydrase0101
Carbonic anhydrase0101
Carbonic anhydrase 120103
Carbonic anhydrase 10305
Carbonic anhydrase 20316
Carbonic anhydrase 30103
5-hydroxytryptamine receptor 2C0101
Androgen receptor0101
5-hydroxytryptamine receptor 2A0101
Carbonic anhydrase 40204
Carbonic anhydrase 60103
Carbonic anhydrase 5A, mitochondrial0101
5-hydroxytryptamine receptor 2B0101
Delta-type opioid receptor0202
Delta-type opioid receptor0101
Mu-type opioid receptor0202
Carbonic anhydrase 5A, mitochondrial0103
Carbonic anhydrase0102
Carbonic anhydrase 70103
Carbonic anhydrase0102
Carbonic anhydrase 0101
Mu-type opioid receptor0101
Beta-carbonic anhydrase 10101
Carbonic anhydrase 20101
Carbonic anhydrase 90204
Carbonic anhydrase, alpha family 0101
Carbonic anhydrase 0102
Carbonic anhydrase0102
Carbonic anhydrase0102
Carbonic anhydrase 0101
Delta carbonic anhydrase0101
Carbonic anhydrase 0102
Carbonic anhydrase 130101
Carbonic anhydrase 40202
Carbonic anhydrase 150102
Carbonic anhydrase 130102
Carbonic anhydrase 140103
Carbonic anhydrase 5B, mitochondrial0103
Glycine receptor subunit alpha-10011
Sodium- and chloride-dependent GABA transporter 20101
Sodium- and chloride-dependent GABA transporter 30101
Glutamate receptor ionotropic, NMDA 1 0427
Sodium- and chloride-dependent glycine transporter 10101
Glutamate receptor ionotropic, NMDA 2A 0427
Glutamate receptor ionotropic, NMDA 2B0427
Glutamate receptor ionotropic, NMDA 2C0427
Large neutral amino acids transporter small subunit 10202
Glutamate receptor ionotropic, NMDA 2D0427
Proton-coupled amino acid transporter 10101
Glutamate receptor ionotropic, NMDA 3B0427
Serine racemase0101
Olfactory receptor 51E20011
Glutamate receptor ionotropic, NMDA 3A0427
Sodium- and chloride-dependent glycine transporter 20101
vitamin D3 receptor isoform VDRA2002
Chain A, HADH2 protein2002
Chain B, HADH2 protein2002
Chain A, Cruzipain1001
vitamin D (1,25- dihydroxyvitamin D3) receptor3003
Voltage-dependent calcium channel gamma-2 subunit1001
Albumin0134
Glutamate receptor 21001
Neuronal acetylcholine receptor subunit beta-20101
Neuronal acetylcholine receptor subunit alpha-70101
glp-1 receptor, partial2002
thioredoxin reductase7007
GLS protein4004
Microtubule-associated protein tau2002
regulator of G-protein signaling 44004
cytochrome P450 family 3 subfamily A polypeptide 44004
NPYLR7B0011
Beta-1 adrenergic receptor 0136
activating transcription factor 63003
beta-2 adrenergic receptor1001
hexokinase-4 isoform 11001
glucokinase regulatory protein1001
Bile salt export pump0404
Beta-2 adrenergic receptor06310
Beta-2 adrenergic receptor0416
Polyunsaturated fatty acid lipoxygenase ALOX150202
Beta-1 adrenergic receptor0529
Beta-2 adrenergic receptor0011
Alpha-2B adrenergic receptor0213
Alpha-2C adrenergic receptor0213
Alpha-2A adrenergic receptor0213
Alpha-1D adrenergic receptor0314
Beta-adrenergic receptor kinase 10011
Alpha-1D adrenergic receptor0023
Beta-3 adrenergic receptor0011
Beta-3 adrenergic receptor0314
Vasopressin V1a receptor0011
Beta-1 adrenergic receptor0213
Alpha-1A adrenergic receptor0135
Alpha-1B adrenergic receptor0023
Beta-2 adrenergic receptor0202
Taste receptor type 2 member 380011
Taste receptor type 2 member 390011
Taste receptor type 2 member 400011
Taste receptor type 2 member 410011
Taste receptor type 2 member 430011
Taste receptor type 2 member 310011
Taste receptor type 2 member 450011
Taste receptor type 2 member 460011
Taste receptor type 2 member 300011
Taste receptor type 2 member 190011
Taste receptor type 2 member 200011
Taste receptor type 2 member 500011
Taste receptor type 2 member 600011
Oxytocin receptor0011
Beta-2 adrenergic receptor 0112
Taste receptor type 2 member 420011
Beta-2 adrenergic receptor0146
Taste receptor type 2 member 160011
Taste receptor type 2 member 140012
Taste receptor type 2 member 130011
Taste receptor type 2 member 100011
Taste receptor type 2 member 90011
Taste receptor type 2 member 80011
Taste receptor type 2 member 70011
Taste receptor type 2 member 50011
Taste receptor type 2 member 40011
Taste receptor type 2 member 30011
Taste receptor type 2 member 10011
2,3-bisphosphoglycerate-independent phosphoglycerate mutase1001
Chain A, MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASE4004
Glutamate receptor ionotropic, NMDA 2D0101
Acetylcholinesterase0202
Glutamate receptor ionotropic, NMDA 3B0101
Rap guanine nucleotide exchange factor 31001
Cholinesterase0202
Glutamate receptor ionotropic, NMDA 10202
Glutamate receptor ionotropic, NMDA 2A0202
Glutamate receptor ionotropic, NMDA 2B0202
Glutamate receptor ionotropic, NMDA 2C0101
Glutamate receptor ionotropic, NMDA 3A0101
Chain A, JmjC domain-containing histone demethylation protein 3A1001
Chain A, 2-oxoglutarate Oxygenase2002
Replicase polyprotein 1ab0101
CAAX prenyl protease 2 isoform 20001
DNA polymerase beta1001
histone acetyltransferase KAT2A isoform 12002
streptokinase A precursor0022
Tubulin beta-4A chain0101
Tubulin beta chain0101
Tubulin alpha-3C chain0101
Tubulin alpha-1B chain0101
Tubulin alpha-4A chain0101
Tubulin beta-4B chain0101
Fatty-acid amide hydrolase 10202
DNA gyrase subunit A0203
DNA primase0101
Tubulin beta-3 chain0101
Tubulin beta-2A chain0101
Tubulin beta-8 chain0101
Tubulin alpha-3E chain0101
Tubulin alpha-1A chain0101
Multidrug and toxin extrusion protein 10202
Tubulin alpha-1C chain0101
Tubulin beta-6 chain0101
Tubulin beta-2B chain0101
Tubulin beta-1 chain0101
Chain A, Beta-lactamase1001
IDH11001
Potassium channel subfamily K member 30101
Potassium channel subfamily K member 20101
Sodium channel protein type 1 subunit alpha0101
Sodium channel protein type 2 subunit alpha0101
Sodium channel protein type 3 subunit alpha0101
Potassium voltage-gated channel subfamily A member 50101
Potassium voltage-gated channel subfamily D member 20101
Potassium channel subfamily K member 180101
Sodium-dependent dopamine transporter0101
arylsulfatase A5005
Cholinesterase0202
Acetylcholinesterase0404
Chain A, Ferritin light chain2002
STE240001
15-hydroxyprostaglandin dehydrogenase [NAD(+)] isoform 12002
nuclear factor erythroid 2-related factor 2 isoform 21001
parathyroid hormone/parathyroid hormone-related peptide receptor precursor1001
CAAX prenyl protease0001
Trypsin0001
DNA gyrase subunit A0102
DNA gyrase subunit B0102
DNA gyrase subunit B0102
cytochrome P450 2C19 precursor1001
Solute carrier family 22 member 10101
Solute carrier family 22 member 20101
Solute carrier family 22 member 1 0405
Sterol O-acyltransferase 10101
Solute carrier family 22 member 20101
Solute carrier family 22 member 30101
Acetylcholinesterase 0101
DNA (cytosine-5)-methyltransferase 10101
Sterol O-acyltransferase 10101
Solute carrier family 22 member 10202
Solute carrier family 22 member 20202
Solute carrier family 22 member 40101
DNA (cytosine-5)-methyltransferase 3-like0101
DNA (cytosine-5)-methyltransferase 3A0101
Chain A, Ferritin light chain0011
Chain A, Ferritin light chain0011
Chain A, Ferritin light chain0011
Chain A, Ferritin light chain0011
Chain A, Ferritin light chain0011
Chain A, Ferritin light chain0011
Chain A, Ferritin light chain0011
cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a3003
nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105), isoform CRA_a3003
Bloom syndrome protein isoform 11001
DNA polymerase iota isoform a (long)1001
Fatty-acid amide hydrolase 10101
UDP-glucuronosyltransferase 1A90001
Gamma-aminobutyric acid receptor subunit alpha-10001
Gamma-aminobutyric acid receptor subunit beta-10001
Gamma-aminobutyric acid receptor subunit alpha-20001
Gamma-aminobutyric acid receptor subunit alpha-30001
Gamma-aminobutyric acid receptor subunit alpha-10112
Gamma-aminobutyric acid receptor subunit beta-10011
Gamma-aminobutyric acid receptor subunit gamma-20112
Gamma-aminobutyric acid receptor subunit alpha-40001
Gamma-aminobutyric acid receptor subunit gamma-20001
Prostaglandin G/H synthase 10101
Sodium- and chloride-dependent GABA transporter 10101
Gamma-aminobutyric acid receptor subunit beta-30112
Gamma-aminobutyric acid receptor subunit alpha-50011
Sodium- and chloride-dependent GABA transporter 20101
Sodium- and chloride-dependent GABA transporter 30101
Gamma-aminobutyric acid receptor subunit alpha-30011
Gamma-aminobutyric acid receptor subunit alpha-20011
Gamma-aminobutyric acid receptor subunit beta-20011
Sodium- and chloride-dependent betaine transporter0101
Gamma-aminobutyric acid receptor subunit alpha-40011
Gamma-aminobutyric acid receptor subunit alpha-60011
UDP-glucuronosyltransferase 1A80001
Cytochrome P450 1A20101
Cytochrome P450 3A40202
5-hydroxytryptamine receptor 1A0101
Cytochrome P450 2D60202
Cytochrome P450 2C9 0202
Alpha-2C adrenergic receptor0124
D(3) dopamine receptor0101
5-hydroxytryptamine receptor 1A0629
Voltage-dependent L-type calcium channel subunit alpha-1C0101
5-hydroxytryptamine receptor 1B0213
5-hydroxytryptamine receptor 1B0606
Adenosine receptor A2a0112
Neuromedin-K receptor0011
Type-1 angiotensin II receptor0112
Cholecystokinin receptor type A0112
Cytochrome P450 2C190101
5-hydroxytryptamine receptor 70112
Vasopressin V1a receptor0112
5-hydroxytryptamine receptor 70202
Cytochrome P450 2J20202
Sodium/bile acid cotransporter0101
Nuclear receptor subfamily 2 group E member 10022
Free fatty acid receptor 30011
Integrin subunit alpha 2b0101
Integrin beta-10101
Integrin alpha-V 0101
Integrin alpha-50101
Integrin beta-3 0101
Chain A, CHORISMATE MUTASE0101
Chain A, TYROSYL-tRNA SYNTHETASE0011
Polyphenol oxidase 20001
Plasma kallikrein0001
Adenosine receptor A10001
Adenosine receptor A2a0001
SLC16A10 protein0001
Carbonic anhydrase-like protein, putative0001
Tubulin--tyrosine ligase0101
Monocarboxylate transporter 100001
glucocerebrosidase1001
lysosomal alpha-glucosidase preproprotein1001
Glycoprotein0101
Muscarinic acetylcholine receptor M20011
Catechol O-methyltransferase0101
Potassium voltage-gated channel subfamily A member 30101
Multidrug resistance-associated protein 1 0214
Kappa-type opioid receptor0101
D(2) dopamine receptor0101
Chloroquine resistance transporter0101
Broad substrate specificity ATP-binding cassette transporter ABCG20112
Solute carrier organic anion transporter family member 1B10202
bromodomain adjacent to zinc finger domain 2B1001
atrial natriuretic peptide receptor 1 precursor1001
ras-related protein Rab-9A1001
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]