Page last updated: 2024-09-27

Absent Right Atrioventricular Connection

Absence of the orifice between the RIGHT ATRIUM and RIGHT VENTRICLE, with the presence of an atrial defect through which all the systemic venous return reaches the left heart. As a result, there is left ventricular hypertrophy (HYPERTROPHY, LEFT VENTRICULAR) because the right ventricle is absent or not functional.

Synonyms(4)

Synonym
Absent Right Atrioventricular Connection
Tricuspid Valve Atresia
Tricuspid Atresia
Atresia, Tricuspid

Research Excerpts

Research

Studies (26)

TimeframeStudies, This Condition (%)All Conditions %
pre-19900 (0.00)23.3326
1990's5 (19.23)12.5806
2000's6 (23.08)18.1394
2010's11 (42.31)28.8240
2020's4 (15.38)9.53
DrugIndicatedRelationship StrengthStudiesTrials
aminocaproic acid0low10
aspirin0medium21
flecainide0low10
furosemide0low10
isoproterenol0low10
ticlopidine0low10
tranexamic acid0low10
triiodothyronine0low10
meglumine0low10
clopidogrel0low10
xenon radioisotopes0low10
bosentan anhydrous0low10
elastin0low10
digoxin0low10
alprostadil0low10
arsenic0low10
macitentan0low10
warfarin0medium31

Protein Targets (380)

ProteinPotency MeasurementsInhibition MeasurementsActivation MeasurementsDrugs
TDP1 protein6006
AR protein8008
glucocorticoid receptor [Homo sapiens]8008
estrogen nuclear receptor alpha9009
peroxisome proliferator activated receptor gamma5005
ATP-binding cassette sub-family C member 30404
Multidrug resistance-associated protein 40405
Bile salt export pump010010
Cellular tumor antigen p534004
Thromboxane-A synthase 0101
Prostaglandin E2 receptor EP3 subtype0101
Prostaglandin E2 receptor EP4 subtype0112
Prostaglandin E2 receptor EP1 subtype0101
Prostacyclin receptor0112
Nuclear receptor subfamily 4 group A member 20011
Solute carrier organic anion transporter family member 2A10102
Nuclear receptor subfamily 4 group A member 20011
Nuclear receptor subfamily 4 group A member 20011
Prostaglandin E2 receptor EP2 subtype0112
Canalicular multispecific organic anion transporter 10303
Solute carrier organic anion transporter family member 2A10001
Solute carrier organic anion transporter family member 2B10101
Solute carrier organic anion transporter family member 3A10001
Chain A, PLASMINOGEN0022
Chain A, PLASMINOGEN0022
Chain A, MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASE4004
Chain A, ATP-DEPENDENT DNA HELICASE Q12002
Chain A, Ferritin light chain2002
Chain A, Apolipoprotein0011
15-lipoxygenase, partial1001
ATAD5 protein, partial3003
aldehyde dehydrogenase 1 family, member A15005
regulator of G-protein signaling 43003
cytochrome P450 family 3 subfamily A polypeptide 48008
EWS/FLI fusion protein9009
nonstructural protein 12002
arylsulfatase A1001
euchromatic histone-lysine N-methyltransferase 24004
D(1A) dopamine receptor1001
chromobox protein homolog 15005
thyroid hormone receptor beta isoform a4004
peptidyl-prolyl cis-trans isomerase NIMA-interacting 11001
geminin6006
histone acetyltransferase KAT2A isoform 11001
lamin isoform A-delta106006
Rap guanine nucleotide exchange factor 31001
Plasminogen0426
Proton-coupled amino acid transporter 10101
Chain A, TYROSYL-DNA PHOSPHODIESTERASE1001
Chain A, Phospholipase A2 isoform 30011
Chain A, HADH2 protein2002
Chain B, HADH2 protein2002
Chain A, 2-oxoglutarate Oxygenase2002
GTP-binding protein (rab7)0011
ras protein, partial0011
interleukin 82002
thioredoxin reductase2002
GLS protein2002
thyroid stimulating hormone receptor1001
hypothetical protein, conserved1001
retinoic acid nuclear receptor alpha variant 16006
estrogen-related nuclear receptor alpha6006
cytochrome P450 2D64004
glucocerebrosidase2002
peroxisome proliferator-activated receptor delta2002
Rac1 protein0011
IDH12002
cell division cycle 42 (GTP binding protein, 25kDa), partial0011
Bloom syndrome protein isoform 11001
15-hydroxyprostaglandin dehydrogenase [NAD(+)] isoform 11001
DNA polymerase iota isoform a (long)2002
DNA polymerase kappa isoform 12002
muscarinic acetylcholine receptor M11001
lethal factor (plasmid)2002
Prostaglandin-H2 D-isomerase0101
Solute carrier family 22 member 60202
Prostaglandin G/H synthase 1 0101
Prostaglandin G/H synthase 2 0101
Epidermal growth factor receptor0101
Carbonic anhydrase 10304
Carbonic anhydrase 20304
Fatty acid-binding protein, liver0101
Integrin beta-31102
Myeloperoxidase0101
Prostaglandin G/H synthase 10101
Seed linoleate 13S-lipoxygenase-10101
Integrin alpha-IIb1102
Glutathione hydrolase 1 proenzyme0101
Prostaglandin G/H synthase 10202
Adenosine receptor A10101
Adenosine receptor A2a0101
Substance-P receptor0101
Prostaglandin G/H synthase 20202
Urotensin-2 receptor0101
4-aminobutyrate aminotransferase, mitochondrial0101
Nuclear receptor ROR-gamma2114
Ras-related protein Rab-2A0011
Gamma-aminobutyric acid receptor subunit alpha-11113
Prostaglandin G/H synthase 20101
Rho-associated protein kinase 20101
Nicotinate phosphoribosyltransferase0101
Solute carrier family 22 member 200101
Solute carrier family 22 member 60101
Sigma non-opioid intracellular receptor 10213
Sigma non-opioid intracellular receptor 10011
phosphopantetheinyl transferase2002
RAR-related orphan receptor gamma4004
GLI family zinc finger 34004
estrogen receptor 2 (ER beta)3003
progesterone receptor5005
pregnane X nuclear receptor5005
G2002
vitamin D (1,25- dihydroxyvitamin D3) receptor3003
activating transcription factor 64004
v-jun sarcoma virus 17 oncogene homolog (avian)3003
vitamin D3 receptor isoform VDRA2002
heat shock protein beta-12002
nuclear factor erythroid 2-related factor 2 isoform 15005
nuclear receptor ROR-gamma isoform 12002
Bile salt export pump0505
Nuclear receptor subfamily 1 group I member 20011
Interferon beta4004
HLA class I histocompatibility antigen, B alpha chain 2002
Endothelin receptor type B0202
Endothelin receptor type B0314
Endothelin-1 receptor0303
Endothelin-1 receptor0213
Endothelin receptor type B0011
Deoxyhypusine synthase0101
Sodium/bile acid cotransporter0303
Endothelin-1 receptor0101
Inositol hexakisphosphate kinase 12002
cytochrome P450 2C9, partial2002
parathyroid hormone/parathyroid hormone-related peptide receptor precursor3003
Cytochrome P450 2C80202
Cytochrome P450 2B60303
Liver carboxylesterase 10001
Sodium-dependent serotonin transporter0202
Cytochrome P450 2C190303
Rap guanine nucleotide exchange factor 41001
P2Y purinoceptor 120101
Chain A, Beta-lactamase2002
Chain A, Cruzipain1001
PAX80001
SMAD family member 21001
PPM1D protein2002
SMAD family member 31001
STAT3, partial0101
thioredoxin glutathione reductase1001
Smad31001
nuclear receptor subfamily 1, group I, member 33003
retinoid X nuclear receptor alpha1001
farnesoid X nuclear receptor3003
67.9K protein1001
alpha-galactosidase1001
cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a2002
thyroid stimulating hormone receptor3003
nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105), isoform CRA_a3003
NPC intracellular cholesterol transporter 1 precursor1001
cellular tumor antigen p53 isoform a1001
tumor necrosis factor1001
nuclear factor erythroid 2-related factor 2 isoform 21001
thyroid hormone receptor beta isoform 26006
ras-related protein Rab-9A1001
signal transducer and activator of transcription 1-alpha/beta isoform alpha0101
Solute carrier organic anion transporter family member 1A40204
Voltage-dependent calcium channel gamma-2 subunit1001
Sodium/potassium-transporting ATPase subunit alpha-1 0202
Sodium/potassium-transporting ATPase subunit beta-10202
Sodium/potassium-transporting ATPase subunit alpha-20101
Sodium/potassium-transporting ATPase subunit alpha-3 0101
ATP-dependent translocase ABCB10101
Sodium/potassium-transporting ATPase subunit beta-1 0101
ATP-dependent translocase ABCB10102
Cytochrome P450 3A40101
Replicase polyprotein 1ab0101
Sodium/potassium-transporting ATPase subunit alpha-30101
Sodium/potassium-transporting ATPase subunit beta-20101
Glutamate receptor 21001
ATP-dependent translocase ABCB10101
Sodium/potassium-transporting ATPase subunit alpha-20202
Sodium/potassium-transporting ATPase subunit alpha-10101
Sodium/potassium-transporting ATPase subunit beta-30101
Sodium/potassium-transporting ATPase subunit gamma0101
Sodium/potassium-transporting ATPase subunit alpha-40101
Sodium/potassium-transporting ATPase subunit alpha-40101
Solute carrier organic anion transporter family member 4C10002
Solute carrier organic anion transporter family member 4C10002
ATPase family AAA domain-containing protein 51001
Ataxin-21001
Solute carrier organic anion transporter family member 1A40001
Solute carrier organic anion transporter family member 1B30102
Solute carrier organic anion transporter family member 1B10102
potassium voltage-gated channel subfamily H member 2 isoform d2002
Voltage-dependent L-type calcium channel subunit alpha-1F0101
Cytochrome P450 2C9 0404
Potassium voltage-gated channel subfamily A member 50101
Cytochrome P450 2J20303
Voltage-dependent L-type calcium channel subunit alpha-1D 0101
Potassium voltage-gated channel subfamily A member 10101
Potassium voltage-gated channel subfamily H member 20101
Voltage-dependent L-type calcium channel subunit alpha-1S0101
Voltage-dependent L-type calcium channel subunit alpha-1C0101
Sodium channel protein type 5 subunit alpha0101
Potassium voltage-gated channel subfamily D member 20101
aryl hydrocarbon receptor2002
thyrotropin-releasing hormone receptor1001
Carbonic anhydrase 120102
Albumin0112
Carbonic anhydrase 30101
Glucose-6-phosphate 1-dehydrogenase0101
Carbonic anhydrase 40102
Carbonic anhydrase 60102
Serum paraoxonase/arylesterase 10101
Corticosteroid 11-beta-dehydrogenase isozyme 10101
Carbonic anhydrase 5A, mitochondrial0102
Carbonic anhydrase 70102
Adenosine receptor A10101
Corticosteroid 11-beta-dehydrogenase isozyme 10101
6-phosphogluconate dehydrogenase, decarboxylating0101
Spike glycoprotein3003
Holo-[acyl-carrier-protein] synthase0101
Carbonic anhydrase 90102
Multidrug and toxin extrusion protein 10101
Carbonic anhydrase 130102
G-protein coupled receptor 350112
CDGSH iron-sulfur domain-containing protein 10202
Carbonic anhydrase 140102
Broad substrate specificity ATP-binding cassette transporter ABCG20101
Carbonic anhydrase 5B, mitochondrial0102
glp-1 receptor, partial3003
Microtubule-associated protein tau1001
NPYLR7B0011
Beta-1 adrenergic receptor 0012
Histone H2A.x1001
beta-2 adrenergic receptor1001
hexokinase-4 isoform 11001
glucokinase regulatory protein1001
serine/threonine-protein kinase mTOR isoform 11001
peripheral myelin protein 222002
Beta-2 adrenergic receptor0225
Beta-1 adrenergic receptor0213
Beta-2 adrenergic receptor0213
Polyunsaturated fatty acid lipoxygenase ALOX150101
Beta-3 adrenergic receptor0112
D(2) dopamine receptor0101
Alpha-1B adrenergic receptor0202
Beta-1 adrenergic receptor0214
Beta-2 adrenergic receptor0011
Alpha-2B adrenergic receptor0202
D(1A) dopamine receptor0101
D(4) dopamine receptor0101
Alpha-2C adrenergic receptor0202
Alpha-2A adrenergic receptor0202
Alpha-1D adrenergic receptor0202
Beta-adrenergic receptor kinase 10011
Alpha-1D adrenergic receptor0011
Beta-3 adrenergic receptor0011
Beta-3 adrenergic receptor0112
Vasopressin V1a receptor0011
Beta-1 adrenergic receptor0112
Alpha-1A adrenergic receptor0011
Alpha-1B adrenergic receptor0011
Glutamate receptor ionotropic, NMDA 1 0011
D(3) dopamine receptor0101
Alpha-1A adrenergic receptor0202
Histamine H2 receptor0011
D(1A) dopamine receptor1001
Beta-2 adrenergic receptor0101
Taste receptor type 2 member 380011
Taste receptor type 2 member 390011
Taste receptor type 2 member 400011
Taste receptor type 2 member 410011
Taste receptor type 2 member 430011
Taste receptor type 2 member 310011
Taste receptor type 2 member 450011
Taste receptor type 2 member 460011
Taste receptor type 2 member 300011
Taste receptor type 2 member 190011
Taste receptor type 2 member 200011
Taste receptor type 2 member 500011
Taste receptor type 2 member 600011
Oxytocin receptor0011
Glutamate receptor ionotropic, NMDA 2A 0011
Glutamate receptor ionotropic, NMDA 2B0011
Glutamate receptor ionotropic, NMDA 2C0011
Beta-2 adrenergic receptor 0112
Glutamate receptor ionotropic, NMDA 2D0011
Taste receptor type 2 member 420011
Beta-2 adrenergic receptor0022
Glutamate receptor ionotropic, NMDA 3B0011
Taste receptor type 2 member 160011
Taste receptor type 2 member 140011
Taste receptor type 2 member 130011
Taste receptor type 2 member 100011
Taste receptor type 2 member 90011
Taste receptor type 2 member 80011
Taste receptor type 2 member 70011
Taste receptor type 2 member 50011
Taste receptor type 2 member 40011
Taste receptor type 2 member 30011
Taste receptor type 2 member 10011
Glutamate receptor ionotropic, NMDA 3A0011
2,3-bisphosphoglycerate-independent phosphoglycerate mutase1001
ATP-dependent phosphofructokinase1001
Fumarate hydratase1001
polyprotein1001
Chain A, JmjC domain-containing histone demethylation protein 3A1001
Luciferase1001
acetylcholinesterase1001
cytochrome P450 2D6 isoform 11001
cytochrome P450 2C19 precursor1001
ubiquitin carboxyl-terminal hydrolase 2 isoform a1001
cytochrome P450 3A4 isoform 11001
Gamma-aminobutyric acid receptor subunit pi1012
Alpha-2A adrenergic receptor0202
Cytochrome P450 2D60101
Gamma-aminobutyric acid receptor subunit beta-11012
Alpha-2B adrenergic receptor0202
Gamma-aminobutyric acid receptor subunit delta1012
Gamma-aminobutyric acid receptor subunit gamma-21012
Alpha-2C adrenergic receptor0202
Gamma-aminobutyric acid receptor subunit alpha-51012
Gamma-aminobutyric acid receptor subunit alpha-31012
Gamma-aminobutyric acid receptor subunit gamma-11012
Gamma-aminobutyric acid receptor subunit alpha-21012
Gamma-aminobutyric acid receptor subunit alpha-41012
Gamma-aminobutyric acid receptor subunit gamma-31012
Gamma-aminobutyric acid receptor subunit alpha-61012
Gamma-aminobutyric acid receptor subunit beta-31012
Gamma-aminobutyric acid receptor subunit beta-21012
Disintegrin and metalloproteinase domain-containing protein 171001
GABA theta subunit1012
Gamma-aminobutyric acid receptor subunit epsilon1012
Urokinase-type plasminogen activator0101
Chain X, Thyroid hormone receptor beta-10011
Chain X, Thyroid hormone receptor beta-10011
USP1 protein, partial1001
apical membrane antigen 1, AMA11001
muscleblind-like protein 1 isoform 11001
neuropeptide S receptor isoform A1001
Gamma-aminobutyric acid receptor subunit pi0101
Gamma-aminobutyric acid receptor subunit delta0101
Solute carrier organic anion transporter family member 1A50001
Prothrombin0011
Transthyretin0001
Androgen receptor0101
Thyroid hormone receptor alpha0224
Thyroid hormone receptor beta0224
Proliferating cell nuclear antigen0101
Gamma-aminobutyric acid receptor subunit alpha-10101
Thyroid hormone receptor beta0101
Gamma-aminobutyric acid receptor subunit beta-10101
Gamma-aminobutyric acid receptor subunit gamma-20101
Gamma-aminobutyric acid receptor subunit beta-30101
Adenosine receptor A10202
Gamma-aminobutyric acid receptor subunit alpha-50101
Gamma-aminobutyric acid receptor subunit alpha-30101
Peroxisome proliferator-activated receptor gamma0022
Solute carrier organic anion transporter family member 1A20001
Gamma-aminobutyric acid receptor subunit alpha-20101
Gamma-aminobutyric acid receptor subunit beta-20101
Gamma-aminobutyric acid receptor subunit alpha-40101
Solute carrier organic anion transporter family member 1A30001
Gamma-aminobutyric acid receptor subunit epsilon0101
Gamma-aminobutyric acid receptor subunit alpha-60101
Sigma non-opioid intracellular receptor 10011
Gamma-aminobutyric acid receptor subunit gamma-10101
Solute carrier organic anion transporter family member 4A10001
Gamma-aminobutyric acid receptor subunit gamma-30101
Solute carrier organic anion transporter family member 1C10101
Gamma-aminobutyric acid receptor subunit theta0101
Chain A, Putative fructose-1,6-bisphosphate aldolase1001
Albumin0011
Proprotein convertase subtilisin/kexin type 70101
Vitamin K epoxide reductase complex subunit 1-like protein 10101
Vitamin K epoxide reductase complex subunit 10101
Protease 0101
Vitamin K epoxide reductase complex subunit 1-like protein 10101
Vitamin K epoxide reductase complex subunit 1 0202
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]