| Protein | Potency Measurements | Inhibition Measurements | Activation Measurements | Drugs |
|---|
| Chain A, TYROSYL-DNA PHOSPHODIESTERASE | 3 | 0 | 0 | 3 |
| Chain A, Putative fructose-1,6-bisphosphate aldolase | 2 | 0 | 0 | 2 |
| Chain A, HADH2 protein | 3 | 0 | 0 | 3 |
| Chain B, HADH2 protein | 3 | 0 | 0 | 3 |
| Chain A, 2-oxoglutarate Oxygenase | 5 | 0 | 0 | 5 |
| Chain A, Cruzipain | 2 | 0 | 0 | 2 |
| phosphopantetheinyl transferase | 1 | 0 | 0 | 1 |
| USP1 protein, partial | 2 | 0 | 0 | 2 |
| Microtubule-associated protein tau | 1 | 0 | 0 | 1 |
| aldehyde dehydrogenase 1 family, member A1 | 5 | 0 | 0 | 5 |
| vitamin D3 receptor isoform VDRA | 1 | 0 | 0 | 1 |
| DNA polymerase kappa isoform 1 | 1 | 0 | 0 | 1 |
| caspase-1 isoform alpha precursor | 1 | 0 | 0 | 1 |
| lamin isoform A-delta10 | 8 | 0 | 0 | 8 |
| Caspase-7 | 1 | 0 | 0 | 1 |
| Inositol monophosphatase 1 | 1 | 0 | 0 | 1 |
| Solute carrier organic anion transporter family member 1B3 | 0 | 3 | 0 | 4 |
| Solute carrier organic anion transporter family member 1B1 | 0 | 3 | 0 | 4 |
| RAR-related orphan receptor gamma | 6 | 0 | 0 | 6 |
| AR protein | 8 | 0 | 0 | 8 |
| nuclear receptor subfamily 1, group I, member 3 | 5 | 0 | 0 | 5 |
| retinoic acid nuclear receptor alpha variant 1 | 5 | 0 | 0 | 5 |
| thyroid stimulating hormone receptor | 4 | 0 | 0 | 4 |
| nuclear factor erythroid 2-related factor 2 isoform 1 | 6 | 0 | 0 | 6 |
| Cellular tumor antigen p53 | 4 | 0 | 0 | 4 |
| Nuclear receptor ROR-gamma | 2 | 1 | 1 | 4 |
| TDP1 protein | 5 | 0 | 0 | 5 |
| apical membrane antigen 1, AMA1 | 1 | 0 | 0 | 1 |
| 67.9K protein | 2 | 0 | 0 | 2 |
| IDH1 | 3 | 0 | 0 | 3 |
| nuclear factor erythroid 2-related factor 2 isoform 2 | 2 | 0 | 0 | 2 |
| DNA polymerase iota isoform a (long) | 2 | 0 | 0 | 2 |
| urokinase-type plasminogen activator precursor | 1 | 0 | 0 | 1 |
| plasminogen precursor | 1 | 0 | 0 | 1 |
| urokinase plasminogen activator surface receptor precursor | 1 | 0 | 0 | 1 |
| geminin | 5 | 0 | 0 | 5 |
| Lysine-specific demethylase 4A | 0 | 1 | 0 | 1 |
| Guanine nucleotide-binding protein G | 1 | 0 | 0 | 1 |
| Hypoxia-inducible factor 1-alpha | 0 | 0 | 1 | 1 |
| Methylcytosine dioxygenase TET2 | 0 | 1 | 0 | 1 |
| Deoxyhypusine hydroxylase | 0 | 1 | 0 | 1 |
| SMAD family member 2 | 2 | 0 | 0 | 2 |
| ATAD5 protein, partial | 2 | 0 | 0 | 2 |
| SMAD family member 3 | 2 | 0 | 0 | 2 |
| GLI family zinc finger 3 | 6 | 0 | 0 | 6 |
| Thrombopoietin | 1 | 0 | 0 | 1 |
| caspase 7, apoptosis-related cysteine protease | 2 | 0 | 0 | 2 |
| thyroid stimulating hormone receptor | 2 | 0 | 0 | 2 |
| cytochrome P450 family 3 subfamily A polypeptide 4 | 2 | 0 | 0 | 2 |
| estrogen-related nuclear receptor alpha | 5 | 0 | 0 | 5 |
| pregnane X nuclear receptor | 4 | 0 | 0 | 4 |
| estrogen nuclear receptor alpha | 6 | 0 | 0 | 6 |
| G | 1 | 0 | 0 | 1 |
| cytochrome P450 2D6 | 1 | 0 | 0 | 1 |
| caspase-3 | 2 | 0 | 0 | 2 |
| euchromatic histone-lysine N-methyltransferase 2 | 4 | 0 | 0 | 4 |
| cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a | 3 | 0 | 0 | 3 |
| nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105), isoform CRA_a | 2 | 0 | 0 | 2 |
| v-jun sarcoma virus 17 oncogene homolog (avian) | 4 | 0 | 0 | 4 |
| Histone H2A.x | 3 | 0 | 0 | 3 |
| Caspase-7 | 2 | 0 | 0 | 2 |
| cytochrome P450 2D6 isoform 1 | 1 | 0 | 0 | 1 |
| cytochrome P450 2C9 precursor | 1 | 0 | 0 | 1 |
| D(1A) dopamine receptor | 1 | 0 | 0 | 1 |
| caspase-3 | 2 | 0 | 0 | 2 |
| thyroid hormone receptor beta isoform 2 | 4 | 0 | 0 | 4 |
| cytochrome P450 3A4 isoform 1 | 1 | 0 | 0 | 1 |
| muscarinic acetylcholine receptor M1 | 1 | 0 | 0 | 1 |
| Gamma-aminobutyric acid receptor subunit pi | 1 | 0 | 0 | 1 |
| Polyunsaturated fatty acid lipoxygenase ALOX15B | 2 | 0 | 0 | 2 |
| 5-hydroxytryptamine receptor 4 | 0 | 2 | 0 | 2 |
| Bile salt export pump | 0 | 5 | 0 | 5 |
| Interferon beta | 2 | 0 | 0 | 2 |
| HLA class I histocompatibility antigen, B alpha chain | 1 | 0 | 0 | 1 |
| Muscarinic acetylcholine receptor M2 | 0 | 2 | 0 | 2 |
| Muscarinic acetylcholine receptor M4 | 0 | 2 | 0 | 2 |
| Muscarinic acetylcholine receptor M5 | 0 | 2 | 0 | 2 |
| Muscarinic acetylcholine receptor M1 | 0 | 2 | 0 | 2 |
| Angiotensin-converting enzyme | 0 | 2 | 0 | 2 |
| Gamma-aminobutyric acid receptor subunit beta-1 | 1 | 0 | 0 | 1 |
| Gamma-aminobutyric acid receptor subunit delta | 1 | 0 | 0 | 1 |
| Gamma-aminobutyric acid receptor subunit gamma-2 | 1 | 0 | 0 | 1 |
| Gamma-aminobutyric acid receptor subunit alpha-5 | 1 | 0 | 0 | 1 |
| Gamma-aminobutyric acid receptor subunit alpha-3 | 1 | 0 | 0 | 1 |
| Muscarinic acetylcholine receptor M3 | 0 | 2 | 0 | 2 |
| Gamma-aminobutyric acid receptor subunit gamma-1 | 1 | 0 | 0 | 1 |
| Gamma-aminobutyric acid receptor subunit alpha-2 | 1 | 0 | 0 | 1 |
| Histamine H2 receptor | 0 | 2 | 0 | 2 |
| 5-hydroxytryptamine receptor 2A | 0 | 2 | 0 | 2 |
| 5-hydroxytryptamine receptor 2C | 0 | 2 | 0 | 2 |
| Gamma-aminobutyric acid receptor subunit alpha-4 | 1 | 0 | 0 | 1 |
| Gamma-aminobutyric acid receptor subunit gamma-3 | 1 | 0 | 0 | 1 |
| Gamma-aminobutyric acid receptor subunit alpha-6 | 1 | 0 | 0 | 1 |
| D(3) dopamine receptor | 0 | 2 | 0 | 2 |
| 5-hydroxytryptamine receptor 2B | 0 | 2 | 0 | 2 |
| Histamine H2 receptor | 2 | 0 | 0 | 2 |
| 5-hydroxytryptamine receptor 6 | 0 | 2 | 0 | 2 |
| Spike glycoprotein | 3 | 0 | 0 | 3 |
| Gamma-aminobutyric acid receptor subunit alpha-1 | 1 | 0 | 0 | 1 |
| Gamma-aminobutyric acid receptor subunit beta-3 | 1 | 0 | 0 | 1 |
| Gamma-aminobutyric acid receptor subunit beta-2 | 1 | 0 | 0 | 1 |
| Potassium voltage-gated channel subfamily H member 2 | 0 | 2 | 0 | 2 |
| Nuclear receptor subfamily 3 group C member 3 | 0 | 2 | 0 | 2 |
| GABA theta subunit | 1 | 0 | 0 | 1 |
| Inositol hexakisphosphate kinase 1 | 1 | 0 | 0 | 1 |
| Ataxin-2 | 3 | 0 | 0 | 3 |
| Sigma non-opioid intracellular receptor 1 | 0 | 2 | 0 | 2 |
| Gamma-aminobutyric acid receptor subunit epsilon | 1 | 0 | 0 | 1 |
| cytochrome P450 2C9, partial | 1 | 0 | 0 | 1 |
| Chain A, MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASE | 1 | 0 | 0 | 1 |
| Chain A, Beta-lactamase | 1 | 0 | 0 | 1 |
| Chain A, ATP-DEPENDENT DNA HELICASE Q1 | 1 | 0 | 0 | 1 |
| interleukin 8 | 1 | 0 | 0 | 1 |
| PAX8 | 0 | 0 | 0 | 1 |
| PPM1D protein | 1 | 0 | 0 | 1 |
| STAT3, partial | 0 | 1 | 0 | 1 |
| thioredoxin glutathione reductase | 1 | 0 | 0 | 1 |
| Smad3 | 1 | 0 | 0 | 1 |
| estrogen receptor 2 (ER beta) | 3 | 0 | 0 | 3 |
| progesterone receptor | 2 | 0 | 0 | 2 |
| regulator of G-protein signaling 4 | 1 | 0 | 0 | 1 |
| glucocorticoid receptor [Homo sapiens] | 2 | 0 | 0 | 2 |
| retinoid X nuclear receptor alpha | 4 | 0 | 0 | 4 |
| farnesoid X nuclear receptor | 2 | 0 | 0 | 2 |
| peroxisome proliferator-activated receptor delta | 4 | 0 | 0 | 4 |
| peroxisome proliferator activated receptor gamma | 3 | 0 | 0 | 3 |
| vitamin D (1,25- dihydroxyvitamin D3) receptor | 2 | 0 | 0 | 2 |
| alpha-galactosidase | 1 | 0 | 0 | 1 |
| activating transcription factor 6 | 2 | 0 | 0 | 2 |
| NPC intracellular cholesterol transporter 1 precursor | 1 | 0 | 0 | 1 |
| cellular tumor antigen p53 isoform a | 1 | 0 | 0 | 1 |
| tumor necrosis factor | 1 | 0 | 0 | 1 |
| thyroid hormone receptor beta isoform a | 1 | 0 | 0 | 1 |
| parathyroid hormone/parathyroid hormone-related peptide receptor precursor | 1 | 0 | 0 | 1 |
| ras-related protein Rab-9A | 1 | 0 | 0 | 1 |
| signal transducer and activator of transcription 1-alpha/beta isoform alpha | 0 | 1 | 0 | 1 |
| nuclear receptor ROR-gamma isoform 1 | 1 | 0 | 0 | 1 |
| lethal factor (plasmid) | 2 | 0 | 0 | 2 |
| Solute carrier organic anion transporter family member 1A4 | 0 | 1 | 0 | 2 |
| Voltage-dependent calcium channel gamma-2 subunit | 1 | 0 | 0 | 1 |
| Sodium/potassium-transporting ATPase subunit alpha-1 | 0 | 2 | 0 | 2 |
| Sodium/potassium-transporting ATPase subunit beta-1 | 0 | 2 | 0 | 2 |
| Integrin beta-3 | 1 | 0 | 0 | 1 |
| Sodium/potassium-transporting ATPase subunit alpha-2 | 0 | 1 | 0 | 1 |
| Sodium/potassium-transporting ATPase subunit alpha-3 | 0 | 1 | 0 | 1 |
| ATP-dependent translocase ABCB1 | 0 | 1 | 0 | 1 |
| Sodium/potassium-transporting ATPase subunit beta-1 | 0 | 1 | 0 | 1 |
| ATP-dependent translocase ABCB1 | 0 | 1 | 0 | 2 |
| Integrin alpha-IIb | 1 | 0 | 0 | 1 |
| Cytochrome P450 3A4 | 0 | 1 | 0 | 1 |
| Replicase polyprotein 1ab | 0 | 1 | 0 | 1 |
| Sodium/potassium-transporting ATPase subunit alpha-3 | 0 | 1 | 0 | 1 |
| Sodium/potassium-transporting ATPase subunit beta-2 | 0 | 1 | 0 | 1 |
| Glutamate receptor 2 | 1 | 0 | 0 | 1 |
| ATP-dependent translocase ABCB1 | 0 | 1 | 0 | 1 |
| Sodium/potassium-transporting ATPase subunit alpha-2 | 0 | 2 | 0 | 2 |
| Sodium/potassium-transporting ATPase subunit alpha-1 | 0 | 1 | 0 | 1 |
| Sodium/potassium-transporting ATPase subunit beta-3 | 0 | 1 | 0 | 1 |
| Sodium/potassium-transporting ATPase subunit gamma | 0 | 1 | 0 | 1 |
| Sodium/potassium-transporting ATPase subunit alpha-4 | 0 | 1 | 0 | 1 |
| Sodium/potassium-transporting ATPase subunit alpha-4 | 0 | 1 | 0 | 1 |
| Solute carrier organic anion transporter family member 4C1 | 0 | 0 | 0 | 1 |
| Solute carrier organic anion transporter family member 4C1 | 0 | 0 | 0 | 1 |
| ATPase family AAA domain-containing protein 5 | 2 | 0 | 0 | 2 |
| Solute carrier organic anion transporter family member 1A4 | 0 | 0 | 0 | 1 |
| GLS protein | 1 | 0 | 0 | 1 |
| arylsulfatase A | 2 | 0 | 0 | 2 |
| flap endonuclease 1 | 2 | 0 | 0 | 2 |
| Gonadotropin-releasing hormone receptor | 0 | 1 | 0 | 1 |
| Gonadotropin-releasing hormone receptor | 0 | 2 | 0 | 2 |
| endonuclease IV | 1 | 0 | 0 | 1 |
| 15-lipoxygenase, partial | 1 | 0 | 0 | 1 |
| GALC protein | 2 | 0 | 0 | 2 |
| nonstructural protein 1 | 1 | 0 | 0 | 1 |
| Bloom syndrome protein isoform 1 | 2 | 0 | 0 | 2 |
| peripheral myelin protein 22 isoform 1 | 1 | 0 | 0 | 1 |
| cytochrome P450 2C19 precursor | 2 | 0 | 0 | 2 |
| potassium voltage-gated channel subfamily H member 2 isoform d | 1 | 0 | 0 | 1 |
| peripheral myelin protein 22 | 2 | 0 | 0 | 2 |
| M-phase phosphoprotein 8 | 1 | 0 | 0 | 1 |
| ATP-dependent phosphofructokinase | 1 | 0 | 0 | 1 |
| glp-1 receptor, partial | 1 | 0 | 0 | 1 |
| thioredoxin reductase | 2 | 0 | 0 | 2 |
| hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 1 | 0 | 0 | 1 |
| beta-2 adrenergic receptor | 1 | 0 | 0 | 1 |
| lysosomal alpha-glucosidase preproprotein | 1 | 0 | 0 | 1 |
| mu-type opioid receptor isoform MOR-1 | 0 | 0 | 1 | 1 |
| chromobox protein homolog 1 | 2 | 0 | 0 | 2 |
| Vpr | 1 | 0 | 0 | 1 |
| 5-hydroxytryptamine receptor 2A | 0 | 0 | 1 | 1 |
| Neuronal acetylcholine receptor subunit alpha-4 | 1 | 0 | 0 | 1 |
| Neuronal acetylcholine receptor subunit beta-2 | 1 | 0 | 0 | 1 |
| 15-hydroxyprostaglandin dehydrogenase [NAD(+)] isoform 1 | 2 | 0 | 0 | 2 |
| Pyridoxal kinase | 0 | 0 | 0 | 1 |
| Bile salt export pump | 0 | 2 | 0 | 2 |
| chaperonin-containing TCP-1 beta subunit homolog | 1 | 0 | 0 | 1 |
| survival motor neuron protein isoform d | 1 | 0 | 0 | 1 |
| histone acetyltransferase KAT2A isoform 1 | 1 | 0 | 0 | 1 |
| Estrogen receptor beta | 0 | 0 | 0 | 1 |
| Inhibitor of nuclear factor kappa-B kinase subunit beta | 0 | 0 | 0 | 1 |
| Solute carrier family 22 member 6 | 0 | 1 | 0 | 1 |
| Polyphenol oxidase 2 | 0 | 1 | 0 | 2 |
| Carbonic anhydrase 12 | 0 | 1 | 0 | 1 |
| 5'-AMP-activated protein kinase subunit beta-2 | 0 | 0 | 0 | 1 |
| Carbonic anhydrase 1 | 0 | 2 | 0 | 2 |
| Carbonic anhydrase 2 | 0 | 2 | 0 | 2 |
| Albumin | 0 | 1 | 0 | 1 |
| Polymerase acidic protein | 0 | 0 | 1 | 1 |
| Carbonic anhydrase 3 | 0 | 1 | 0 | 1 |
| Stromelysin-1 | 0 | 0 | 1 | 1 |
| Tyrosine-protein phosphatase YopH | 0 | 1 | 0 | 1 |
| High mobility group protein B1 | 0 | 0 | 1 | 1 |
| Aldo-keto reductase family 1 member B1 | 0 | 1 | 0 | 1 |
| Prolyl 4-hydroxylase subunit alpha-1 | 0 | 1 | 0 | 1 |
| Tyrosine-protein phosphatase non-receptor type 1 | 0 | 1 | 0 | 3 |
| Estrogen receptor | 0 | 0 | 0 | 1 |
| Acetylcholinesterase | 0 | 1 | 0 | 1 |
| Carbonic anhydrase 4 | 0 | 1 | 0 | 1 |
| Prostaglandin G/H synthase 1 | 0 | 1 | 0 | 1 |
| Carbonic anhydrase 6 | 0 | 1 | 0 | 1 |
| Cystathionine gamma-lyase | 0 | 1 | 0 | 1 |
| Carbonic anhydrase 5A, mitochondrial | 0 | 1 | 0 | 1 |
| Prostaglandin G/H synthase 2 | 0 | 1 | 0 | 1 |
| Carbonic anhydrase 7 | 0 | 1 | 0 | 1 |
| 5'-AMP-activated protein kinase subunit gamma-1 | 0 | 0 | 0 | 1 |
| 5'-AMP-activated protein kinase catalytic subunit alpha-2 | 0 | 0 | 0 | 1 |
| Xanthine dehydrogenase/oxidase | 0 | 1 | 0 | 1 |
| 5'-AMP-activated protein kinase catalytic subunit alpha-1 | 0 | 0 | 0 | 1 |
| Carbonic anhydrase 9 | 0 | 1 | 0 | 1 |
| Carbonic anhydrase | 0 | 1 | 0 | 1 |
| Solute carrier family 22 member 6 | 0 | 1 | 0 | 1 |
| Solute carrier family 22 member 7 | 0 | 0 | 0 | 1 |
| Nicotinate phosphoribosyltransferase | 0 | 1 | 0 | 1 |
| Solute carrier family 22 member 20 | 0 | 1 | 0 | 1 |
| Solute carrier family 22 member 8 | 0 | 1 | 0 | 1 |
| Solute carrier family 22 member 6 | 0 | 1 | 0 | 1 |
| Ubiquitin-like domain-containing CTD phosphatase 1 | 0 | 1 | 0 | 1 |
| Carbonic anhydrase 15 | 0 | 1 | 0 | 1 |
| Carbonic anhydrase 13 | 0 | 1 | 0 | 1 |
| 5'-AMP-activated protein kinase subunit gamma-3 | 0 | 0 | 0 | 1 |
| 5'-AMP-activated protein kinase subunit gamma-2 | 0 | 0 | 0 | 1 |
| Carbonic anhydrase 14 | 0 | 1 | 0 | 1 |
| Carbonic anhydrase 5B, mitochondrial | 0 | 1 | 0 | 1 |
| 5'-AMP-activated protein kinase subunit beta-1 | 0 | 0 | 0 | 1 |
| Luciferase | 1 | 0 | 0 | 1 |
| hypoxia-inducible factor 1 alpha subunit | 1 | 0 | 0 | 1 |
| heat shock protein beta-1 | 1 | 0 | 0 | 1 |
| Chain A, PLASMINOGEN | 0 | 0 | 1 | 1 |
| Chain A, PLASMINOGEN | 0 | 0 | 1 | 1 |
| EWS/FLI fusion protein | 1 | 0 | 0 | 1 |
| Plasminogen | 0 | 2 | 1 | 3 |
| Urokinase-type plasminogen activator | 0 | 1 | 0 | 1 |
| Rap guanine nucleotide exchange factor 3 | 1 | 0 | 0 | 1 |
| Urease subunit alpha | 0 | 1 | 0 | 1 |
| Urease subunit beta | 0 | 1 | 0 | 1 |
| Olfactory receptor 51E2 | 0 | 0 | 1 | 1 |
| [prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023] |