Page last updated: 2024-09-27

ALTE Apparent Life-Threatening Event

An event experienced by an infant or a child that is characterized by some combination of apnea, color change, change in muscle tone, choking, and gagging.

Synonyms(6)

Synonym
Apparent Life-Threatening Event
Idiopathic Apparent Life-Threatening Event
Brief, Resolved, Unexplained Event
Infantile Apparent Life-Threatening Event
BRUE Brief, Resolved, Unexplained Event
ALTE Apparent Life-Threatening Event

Research

Studies (8)

TimeframeStudies, This Condition (%)All Conditions %
pre-19900 (0.00)23.3326
1990's0 (0.00)12.5806
2000's0 (0.00)18.1394
2010's6 (75.00)28.8240
2020's2 (25.00)9.53
DrugIndicatedRelationship StrengthStudiesTrials
apnea0medium71
naloxone0low10

Protein Targets (46)

ProteinPotency MeasurementsInhibition MeasurementsActivation MeasurementsDrugs
thioredoxin reductase1001
ATAD5 protein, partial1001
TDP1 protein1001
Microtubule-associated protein tau1001
estrogen-related nuclear receptor alpha1001
arylsulfatase A1001
euchromatic histone-lysine N-methyltransferase 21001
Bloom syndrome protein isoform 11001
D(1A) dopamine receptor1001
lamin isoform A-delta101001
neuropeptide S receptor isoform A1001
RAR-related orphan receptor gamma1001
pregnane X nuclear receptor1001
estrogen nuclear receptor alpha1001
cytochrome P450 2D61001
ATP-binding cassette sub-family C member 30101
Multidrug resistance-associated protein 40101
Bile salt export pump0101
Muscarinic acetylcholine receptor M10101
Muscarinic acetylcholine receptor M30101
Muscarinic acetylcholine receptor M40101
Muscarinic acetylcholine receptor M50101
Cytochrome P450 2D60101
Muscarinic acetylcholine receptor M20101
Cytochrome P450 2C9 0101
Histidine decarboxylase0011
D(3) dopamine receptor0101
Adenosine receptor A10101
Delta-type opioid receptor0214
Delta-type opioid receptor0224
Kappa-type opioid receptor0102
Mu-type opioid receptor0224
Kappa-type opioid receptor0123
Mu-type opioid receptor0214
Delta-type opioid receptor0214
Kappa-type opioid receptor0213
Kappa-type opioid receptor0225
Mu-type opioid receptor0102
Cytochrome P450 2J20101
Mu-type opioid receptor0213
Sigma non-opioid intracellular receptor 10101
Beta-2 adrenergic receptor0101
Canalicular multispecific organic anion transporter 10101
Sigma non-opioid intracellular receptor 10101
UDP-glucuronosyltransferase 1A80001
Sigma non-opioid intracellular receptor 10101
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]