Protein | Potency Measurements | Inhibition Measurements | Activation Measurements | Drugs |
Chain A, Ferritin light chain | 3 | 0 | 0 | 3 |
glp-1 receptor, partial | 2 | 0 | 0 | 2 |
phosphopantetheinyl transferase | 3 | 0 | 0 | 3 |
hypoxia-inducible factor 1 alpha subunit | 6 | 0 | 0 | 6 |
RAR-related orphan receptor gamma | 14 | 0 | 0 | 14 |
SMAD family member 2 | 9 | 0 | 0 | 9 |
Fumarate hydratase | 3 | 0 | 0 | 3 |
SMAD family member 3 | 9 | 0 | 0 | 9 |
TDP1 protein | 17 | 0 | 0 | 17 |
GLI family zinc finger 3 | 18 | 0 | 0 | 18 |
Microtubule-associated protein tau | 4 | 0 | 0 | 4 |
AR protein | 22 | 0 | 0 | 22 |
Smad3 | 2 | 0 | 0 | 2 |
hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 2 | 0 | 0 | 2 |
estrogen receptor 2 (ER beta) | 12 | 0 | 0 | 12 |
nuclear receptor subfamily 1, group I, member 3 | 10 | 0 | 0 | 10 |
progesterone receptor | 17 | 0 | 0 | 17 |
cytochrome P450 family 3 subfamily A polypeptide 4 | 8 | 0 | 0 | 8 |
glucocorticoid receptor [Homo sapiens] | 21 | 0 | 0 | 21 |
retinoic acid nuclear receptor alpha variant 1 | 18 | 0 | 0 | 18 |
retinoid X nuclear receptor alpha | 15 | 0 | 0 | 15 |
estrogen-related nuclear receptor alpha | 16 | 0 | 0 | 16 |
farnesoid X nuclear receptor | 12 | 0 | 0 | 12 |
pregnane X nuclear receptor | 16 | 0 | 0 | 16 |
estrogen nuclear receptor alpha | 21 | 0 | 0 | 21 |
G | 7 | 0 | 0 | 7 |
cytochrome P450 2D6 | 3 | 0 | 0 | 3 |
polyprotein | 3 | 0 | 0 | 3 |
67.9K protein | 2 | 0 | 0 | 2 |
bromodomain adjacent to zinc finger domain 2B | 1 | 0 | 0 | 1 |
peroxisome proliferator-activated receptor delta | 10 | 0 | 0 | 10 |
peroxisome proliferator activated receptor gamma | 12 | 0 | 0 | 12 |
vitamin D (1,25- dihydroxyvitamin D3) receptor | 14 | 0 | 0 | 14 |
IDH1 | 4 | 0 | 0 | 4 |
cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a | 15 | 0 | 0 | 15 |
thyroid stimulating hormone receptor | 8 | 0 | 0 | 8 |
activating transcription factor 6 | 6 | 0 | 0 | 6 |
nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105), isoform CRA_a | 7 | 0 | 0 | 7 |
v-jun sarcoma virus 17 oncogene homolog (avian) | 10 | 0 | 0 | 10 |
Histone H2A.x | 8 | 0 | 0 | 8 |
Caspase-7 | 3 | 0 | 0 | 3 |
vitamin D3 receptor isoform VDRA | 4 | 0 | 0 | 4 |
nuclear factor erythroid 2-related factor 2 isoform 2 | 4 | 0 | 0 | 4 |
parathyroid hormone/parathyroid hormone-related peptide receptor precursor | 2 | 0 | 0 | 2 |
caspase-3 | 3 | 0 | 0 | 3 |
thyroid hormone receptor beta isoform 2 | 17 | 0 | 0 | 17 |
heat shock protein beta-1 | 7 | 0 | 0 | 7 |
huntingtin isoform 2 | 1 | 0 | 0 | 1 |
nuclear factor erythroid 2-related factor 2 isoform 1 | 17 | 0 | 0 | 17 |
nuclear receptor ROR-gamma isoform 1 | 5 | 0 | 0 | 5 |
geminin | 15 | 0 | 0 | 15 |
survival motor neuron protein isoform d | 6 | 0 | 0 | 6 |
replicative DNA helicase | 0 | 0 | 0 | 1 |
recombinase A | 0 | 0 | 1 | 1 |
lamin isoform A-delta10 | 7 | 0 | 0 | 7 |
neuropeptide S receptor isoform A | 3 | 0 | 0 | 3 |
Voltage-dependent calcium channel gamma-2 subunit | 9 | 0 | 0 | 9 |
Interferon beta | 9 | 0 | 0 | 9 |
HLA class I histocompatibility antigen, B alpha chain | 7 | 0 | 0 | 7 |
Cellular tumor antigen p53 | 11 | 0 | 0 | 11 |
Glutamate receptor 2 | 9 | 0 | 0 | 9 |
Alpha-synuclein | 3 | 2 | 0 | 5 |
Spike glycoprotein | 4 | 0 | 0 | 4 |
Guanine nucleotide-binding protein G | 4 | 0 | 0 | 4 |
Inositol hexakisphosphate kinase 1 | 7 | 0 | 0 | 7 |
cytochrome P450 2C9, partial | 7 | 0 | 0 | 7 |
acetylcholinesterase | 3 | 0 | 0 | 3 |
pregnane X receptor | 6 | 0 | 0 | 6 |
arylsulfatase A | 2 | 0 | 0 | 2 |
euchromatic histone-lysine N-methyltransferase 2 | 5 | 0 | 0 | 5 |
nuclear receptor subfamily 1, group I, member 2 | 3 | 0 | 0 | 3 |
chromobox protein homolog 1 | 4 | 0 | 0 | 4 |
histone acetyltransferase KAT2A isoform 1 | 1 | 0 | 0 | 1 |
Glucocorticoid receptor | 0 | 17 | 2 | 20 |
Sex hormone-binding globulin | 0 | 1 | 12 | 13 |
Glycine receptor subunit alpha-1 | 0 | 16 | 0 | 16 |
Corticosteroid-binding globulin | 0 | 8 | 0 | 8 |
Adenosine receptor A3 | 0 | 4 | 0 | 4 |
Replicase polyprotein 1ab | 0 | 1 | 0 | 1 |
Androgen receptor | 0 | 15 | 1 | 16 |
Alpha-1B adrenergic receptor | 0 | 4 | 0 | 4 |
Glycine receptor subunit beta | 0 | 16 | 0 | 16 |
Glycine receptor subunit alpha-2 | 0 | 16 | 0 | 16 |
Glycine receptor subunit alpha-3 | 0 | 16 | 0 | 16 |
Mitogen-activated protein kinase 3 | 0 | 1 | 0 | 1 |
Alpha-1A adrenergic receptor | 0 | 4 | 0 | 4 |
Sodium-dependent dopamine transporter | 0 | 4 | 0 | 4 |
TAR DNA-binding protein 43 | 6 | 0 | 0 | 6 |
ATP-dependent phosphofructokinase | 2 | 0 | 0 | 2 |
thyroid hormone receptor beta isoform a | 4 | 0 | 0 | 4 |
Mineralocorticoid receptor | 0 | 3 | 2 | 5 |
Mineralocorticoid receptor | 0 | 2 | 0 | 2 |
Solute carrier organic anion transporter family member 1A1 | 0 | 1 | 0 | 2 |
Chain A, MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASE | 4 | 0 | 0 | 4 |
ATP-binding cassette sub-family C member 3 | 0 | 6 | 0 | 6 |
Multidrug resistance-associated protein 4 | 0 | 6 | 0 | 7 |
Bile salt export pump | 0 | 11 | 0 | 11 |
Aromatase | 0 | 5 | 0 | 8 |
Cytochrome P450 2C9 | 0 | 2 | 0 | 2 |
Amine oxidase [flavin-containing] A | 0 | 1 | 0 | 1 |
UDP-glucuronosyltransferase 1A4 | 0 | 1 | 0 | 2 |
Canalicular multispecific organic anion transporter 1 | 0 | 6 | 0 | 6 |
Chain A, HADH2 protein | 5 | 0 | 0 | 5 |
Chain B, HADH2 protein | 5 | 0 | 0 | 5 |
interleukin 8 | 5 | 0 | 0 | 5 |
aldehyde dehydrogenase 1 family, member A1 | 8 | 0 | 0 | 8 |
regulator of G-protein signaling 4 | 3 | 0 | 0 | 3 |
nonstructural protein 1 | 2 | 0 | 0 | 2 |
Bloom syndrome protein isoform 1 | 2 | 0 | 0 | 2 |
peripheral myelin protein 22 isoform 1 | 3 | 0 | 0 | 3 |
potassium voltage-gated channel subfamily H member 2 isoform d | 2 | 0 | 0 | 2 |
importin subunit beta-1 isoform 1 | 1 | 0 | 0 | 1 |
mitogen-activated protein kinase 1 | 2 | 0 | 0 | 2 |
nuclear factor NF-kappa-B p105 subunit isoform 1 | 1 | 0 | 0 | 1 |
snurportin-1 | 1 | 0 | 0 | 1 |
GTP-binding nuclear protein Ran isoform 1 | 1 | 0 | 0 | 1 |
DNA polymerase iota isoform a (long) | 4 | 0 | 0 | 4 |
peripheral myelin protein 22 | 6 | 0 | 0 | 6 |
muscleblind-like protein 1 isoform 1 | 2 | 0 | 0 | 2 |
Beta-glucuronidase | 0 | 2 | 0 | 2 |
Cholinesterase | 0 | 1 | 0 | 1 |
Gastrin/cholecystokinin type B receptor | 0 | 0 | 0 | 1 |
Testosterone 17-beta-dehydrogenase 3 | 0 | 2 | 0 | 2 |
Nuclear receptor ROR-gamma | 8 | 0 | 0 | 8 |
Chain A, TYROSYL-DNA PHOSPHODIESTERASE | 2 | 0 | 0 | 2 |
thioredoxin reductase | 3 | 0 | 0 | 3 |
ATAD5 protein, partial | 2 | 0 | 0 | 2 |
thioredoxin glutathione reductase | 2 | 0 | 0 | 2 |
EWS/FLI fusion protein | 2 | 0 | 0 | 2 |
P53 | 1 | 0 | 0 | 1 |
aryl hydrocarbon receptor | 3 | 0 | 0 | 3 |
hemoglobin subunit beta | 1 | 0 | 0 | 1 |
cellular tumor antigen p53 isoform a | 1 | 0 | 0 | 1 |
cytochrome P450 3A4 isoform 1 | 5 | 0 | 0 | 5 |
M-phase phosphoprotein 8 | 2 | 0 | 0 | 2 |
muscarinic acetylcholine receptor M1 | 2 | 0 | 0 | 2 |
Gamma-aminobutyric acid receptor subunit pi | 5 | 0 | 0 | 5 |
Bile salt export pump | 0 | 2 | 0 | 2 |
Gamma-aminobutyric acid receptor subunit beta-1 | 5 | 0 | 0 | 5 |
Gamma-aminobutyric acid receptor subunit delta | 5 | 0 | 0 | 5 |
Gamma-aminobutyric acid receptor subunit gamma-2 | 5 | 0 | 0 | 5 |
Gamma-aminobutyric acid receptor subunit alpha-5 | 5 | 0 | 0 | 5 |
Gamma-aminobutyric acid receptor subunit alpha-3 | 5 | 0 | 0 | 5 |
Gamma-aminobutyric acid receptor subunit gamma-1 | 5 | 0 | 0 | 5 |
Gamma-aminobutyric acid receptor subunit alpha-2 | 5 | 0 | 0 | 5 |
Gamma-aminobutyric acid receptor subunit alpha-4 | 5 | 0 | 0 | 5 |
Gamma-aminobutyric acid receptor subunit gamma-3 | 5 | 0 | 0 | 5 |
Gamma-aminobutyric acid receptor subunit alpha-6 | 5 | 0 | 0 | 5 |
Gamma-aminobutyric acid receptor subunit alpha-1 | 5 | 0 | 0 | 5 |
Gamma-aminobutyric acid receptor subunit beta-3 | 5 | 0 | 0 | 5 |
Gamma-aminobutyric acid receptor subunit beta-2 | 5 | 0 | 0 | 5 |
GABA theta subunit | 5 | 0 | 0 | 5 |
ATPase family AAA domain-containing protein 5 | 3 | 0 | 0 | 3 |
Ataxin-2 | 3 | 0 | 0 | 3 |
Gamma-aminobutyric acid receptor subunit epsilon | 5 | 0 | 0 | 5 |
Protein-arginine deiminase type-4 | 0 | 1 | 0 | 1 |
endonuclease IV | 1 | 0 | 0 | 1 |
dopamine D1 receptor | 1 | 0 | 0 | 1 |
GLS protein | 1 | 0 | 0 | 1 |
atrial natriuretic peptide receptor 1 precursor | 1 | 0 | 0 | 1 |
flap endonuclease 1 | 1 | 0 | 0 | 1 |
Potassium voltage-gated channel subfamily A member 1 | 0 | 0 | 1 | 1 |
Multidrug and toxin extrusion protein 1 | 0 | 2 | 0 | 2 |
Beta-glucuronidase | 0 | 1 | 0 | 1 |
Glucose-6-phosphate 1-dehydrogenase | 0 | 3 | 0 | 3 |
G-protein coupled bile acid receptor 1 | 0 | 0 | 2 | 2 |
Glucose-6-phosphate 1-dehydrogenase | 0 | 1 | 0 | 1 |
NPC1-like intracellular cholesterol transporter 1 | 0 | 0 | 1 | 1 |
Chain A, Sex Hormone-Binding Globulin | 0 | 0 | 1 | 1 |
thyrotropin-releasing hormone receptor | 1 | 0 | 0 | 1 |
transcriptional regulator ERG isoform 3 | 3 | 0 | 0 | 3 |
Plasma kallikrein | 0 | 1 | 0 | 1 |
Progesterone receptor | 0 | 1 | 0 | 1 |
Progesterone receptor | 0 | 5 | 4 | 9 |
Glucocorticoid receptor | 0 | 1 | 0 | 1 |
Sex hormone-binding globulin | 0 | 1 | 0 | 1 |
Androgen receptor | 0 | 4 | 4 | 10 |
Androgen receptor | 0 | 1 | 2 | 3 |
Angiotensin-converting enzyme | 0 | 0 | 1 | 1 |
Cannabinoid receptor 2 | 0 | 1 | 0 | 1 |
Muscarinic acetylcholine receptor | 0 | 1 | 0 | 1 |
Neuropeptide FF receptor 2 | 0 | 0 | 0 | 1 |
ALK tyrosine kinase receptor | 0 | 1 | 0 | 1 |
Chain A, Cruzipain | 2 | 0 | 0 | 2 |
thyroid stimulating hormone receptor | 2 | 0 | 0 | 2 |
15-hydroxyprostaglandin dehydrogenase [NAD(+)] isoform 1 | 1 | 0 | 0 | 1 |
prostaglandin E2 receptor EP2 subtype | 1 | 0 | 0 | 1 |
Solute carrier family 22 member 2 | 0 | 1 | 0 | 2 |
Solute carrier family 22 member 1 | 0 | 0 | 0 | 1 |
Solute carrier organic anion transporter family member 1A5 | 0 | 0 | 0 | 1 |
Cytochrome P450 3A4 | 0 | 2 | 1 | 3 |
Prostaglandin E2 receptor EP3 subtype | 0 | 1 | 0 | 1 |
Prostaglandin E2 receptor EP4 subtype | 0 | 1 | 0 | 1 |
Prostaglandin E2 receptor EP1 subtype | 0 | 2 | 1 | 3 |
Prostaglandin E2 receptor EP1 subtype | 0 | 1 | 0 | 1 |
Prostaglandin E2 receptor EP4 subtype | 0 | 2 | 1 | 3 |
Prostaglandin F2-alpha receptor | 0 | 0 | 1 | 1 |
Prostaglandin E2 receptor EP4 subtype | 0 | 1 | 1 | 2 |
Prostaglandin E2 receptor EP3 subtype | 0 | 2 | 1 | 3 |
Prostaglandin E2 receptor EP2 subtype | 0 | 2 | 1 | 3 |
Prostacyclin receptor | 0 | 2 | 1 | 3 |
Solute carrier organic anion transporter family member 2A1 | 0 | 0 | 0 | 1 |
Solute carrier family 22 member 6 | 0 | 0 | 0 | 1 |
Solute carrier family 22 member 7 | 0 | 0 | 0 | 1 |
Prostaglandin E2 receptor EP2 subtype | 0 | 1 | 0 | 1 |
Prostaglandin E2 receptor EP2 subtype | 0 | 1 | 1 | 2 |
Solute carrier family 22 member 20 | 0 | 1 | 0 | 1 |
Solute carrier family 22 member 8 | 0 | 0 | 0 | 1 |
Solute carrier family 22 member 6 | 0 | 1 | 0 | 1 |
Solute carrier family 22 member 7 | 0 | 0 | 0 | 1 |
Solute carrier organic anion transporter family member 2A1 | 0 | 0 | 0 | 1 |
Solute carrier family 22 member 11 | 0 | 0 | 0 | 1 |
Solute carrier organic anion transporter family member 1B2 | 0 | 0 | 0 | 1 |
Solute carrier family 22 member 7 | 0 | 0 | 0 | 1 |
Estrogen receptor | 0 | 7 | 2 | 9 |
Polyunsaturated fatty acid lipoxygenase ALOX15 | 0 | 2 | 0 | 2 |
UDP-glucuronosyltransferase 2B7 | 0 | 0 | 0 | 2 |
Sodium-dependent serotonin transporter | 0 | 6 | 0 | 6 |
Lanosterol 14-alpha demethylase | 0 | 0 | 1 | 1 |
Olfactory receptor 51E2 | 0 | 0 | 1 | 1 |
UDP-glucuronosyltransferase 1A10 | 0 | 0 | 0 | 1 |
Luciferase | 3 | 0 | 0 | 3 |
USP1 protein, partial | 2 | 0 | 0 | 2 |
PPM1D protein | 2 | 0 | 0 | 2 |
caspase 7, apoptosis-related cysteine protease | 1 | 0 | 0 | 1 |
caspase-3 | 1 | 0 | 0 | 1 |
lysosomal alpha-glucosidase preproprotein | 1 | 0 | 0 | 1 |
urokinase-type plasminogen activator precursor | 2 | 0 | 0 | 2 |
plasminogen precursor | 2 | 0 | 0 | 2 |
urokinase plasminogen activator surface receptor precursor | 2 | 0 | 0 | 2 |
Vpr | 1 | 0 | 0 | 1 |
Cytochrome P450 2B1 | 0 | 1 | 0 | 1 |
Aldo-keto reductase family 1 member B1 | 0 | 2 | 0 | 2 |
Neuronal acetylcholine receptor subunit alpha-4 | 1 | 0 | 0 | 1 |
Neuronal acetylcholine receptor subunit beta-2 | 1 | 0 | 0 | 1 |
Cytochrome P450 2B6 | 0 | 1 | 0 | 1 |
UDP-glucuronosyltransferase 1A1 | 0 | 1 | 0 | 2 |
Sodium-dependent noradrenaline transporter | 0 | 2 | 0 | 2 |
3-oxo-5-alpha-steroid 4-dehydrogenase 1 | 0 | 1 | 0 | 1 |
Adenosine receptor A2a | 0 | 2 | 0 | 2 |
Mu-type opioid receptor | 0 | 2 | 0 | 2 |
Kappa-type opioid receptor | 0 | 2 | 0 | 2 |
Sulfotransferase 1A1 | 0 | 2 | 1 | 4 |
Aldehyde oxidase | 0 | 1 | 0 | 1 |
Nuclear receptor subfamily 1 group I member 3 | 0 | 1 | 0 | 1 |
Multidrug and toxin extrusion protein 2 | 0 | 1 | 0 | 1 |
Estrogen receptor beta | 0 | 2 | 2 | 4 |
GALC protein | 1 | 0 | 0 | 1 |
Gonadotropin-releasing hormone receptor | 0 | 1 | 0 | 1 |
Gonadotropin-releasing hormone receptor | 0 | 2 | 0 | 2 |
Chain A, Beta-lactamase | 3 | 0 | 0 | 3 |
PINK1 | 1 | 0 | 0 | 1 |
Parkin | 1 | 0 | 0 | 1 |
Histamine H2 receptor | 0 | 2 | 0 | 2 |
5-hydroxytryptamine receptor 1B | 0 | 1 | 0 | 1 |
Aldo-keto reductase family 1 member C3 | 0 | 1 | 0 | 1 |
Aldo-keto reductase family 1 member C2 | 0 | 1 | 0 | 1 |
Aldo-keto reductase family 1 member C1 | 0 | 1 | 0 | 1 |
Chain A, JmjC domain-containing histone demethylation protein 3A | 1 | 0 | 0 | 1 |
Polyphenol oxidase 2 | 0 | 2 | 0 | 3 |
Dopamine beta-hydroxylase | 0 | 2 | 0 | 2 |
Lactoperoxidase | 0 | 1 | 0 | 1 |
Lanosterol 14-alpha demethylase | 0 | 2 | 0 | 2 |
glucocerebrosidase | 1 | 0 | 0 | 1 |
Estrogen receptor | 0 | 0 | 1 | 1 |
Estrogen receptor beta | 0 | 0 | 1 | 1 |
DNA polymerase kappa isoform 1 | 1 | 0 | 0 | 1 |
Nuclear receptor subfamily 1 group I member 2 | 0 | 0 | 1 | 1 |
Cytochrome P450 3A5 | 0 | 1 | 0 | 1 |
Serine/threonine-protein kinase mTOR | 0 | 1 | 0 | 1 |
Peptidyl-prolyl cis-trans isomerase FKBP1A | 0 | 2 | 1 | 3 |
Peptidyl-prolyl cis-trans isomerase FKBP1B | 0 | 0 | 1 | 1 |
Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform | 0 | 1 | 0 | 1 |
Peptidyl-prolyl cis-trans isomerase FKBP5 | 0 | 1 | 0 | 1 |
Splicing factor 3B subunit 3 | 0 | 1 | 0 | 1 |
Broad substrate specificity ATP-binding cassette transporter ABCG2 | 0 | 1 | 0 | 1 |
Solute carrier organic anion transporter family member 1B1 | 0 | 1 | 0 | 1 |
Chain A, Putative fructose-1,6-bisphosphate aldolase | 1 | 0 | 0 | 1 |
Chain A, 2-oxoglutarate Oxygenase | 1 | 0 | 0 | 1 |
Albumin | 0 | 0 | 1 | 1 |
Albumin | 0 | 0 | 1 | 1 |
Proprotein convertase subtilisin/kexin type 7 | 0 | 1 | 0 | 1 |
Vitamin K epoxide reductase complex subunit 1-like protein 1 | 0 | 1 | 0 | 1 |
Vitamin K epoxide reductase complex subunit 1 | 0 | 1 | 0 | 1 |
Protease | 0 | 1 | 0 | 1 |
Vitamin K epoxide reductase complex subunit 1-like protein 1 | 0 | 1 | 0 | 1 |
Vitamin K epoxide reductase complex subunit 1 | 0 | 2 | 0 | 2 |
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023] |