| Protein | Potency Measurements | Inhibition Measurements | Activation Measurements | Drugs |
|---|
| Chain A, MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASE | 2 | 0 | 0 | 2 |
| Chain A, TYROSYL-DNA PHOSPHODIESTERASE | 2 | 0 | 0 | 2 |
| Chain A, Ferritin light chain | 2 | 0 | 0 | 2 |
| phosphopantetheinyl transferase | 3 | 0 | 0 | 3 |
| aldehyde dehydrogenase 1 family, member A1 | 4 | 0 | 0 | 4 |
| arylsulfatase A | 1 | 0 | 0 | 1 |
| euchromatic histone-lysine N-methyltransferase 2 | 3 | 0 | 0 | 3 |
| Bloom syndrome protein isoform 1 | 2 | 0 | 0 | 2 |
| cytochrome P450 2C19 precursor | 1 | 0 | 0 | 1 |
| lethal factor (plasmid) | 1 | 0 | 0 | 1 |
| lamin isoform A-delta10 | 1 | 0 | 0 | 1 |
| Metabotropic glutamate receptor 6 | 0 | 0 | 1 | 1 |
| Excitatory amino acid transporter 4 | 0 | 1 | 0 | 1 |
| Glutamate transporter homolog | 0 | 0 | 1 | 1 |
| Carbonic anhydrase 1 | 0 | 0 | 0 | 1 |
| Carbonic anhydrase 2 | 0 | 0 | 0 | 1 |
| N(4)-(beta-N-acetylglucosaminyl)-L-asparaginase | 0 | 1 | 0 | 1 |
| 5-hydroxytryptamine receptor 1D | 0 | 0 | 0 | 1 |
| Glutamate receptor ionotropic, NMDA 1 | 0 | 3 | 1 | 4 |
| Excitatory amino acid transporter 1 | 0 | 1 | 0 | 1 |
| Excitatory amino acid transporter 2 | 0 | 1 | 0 | 1 |
| Excitatory amino acid transporter 3 | 0 | 1 | 0 | 1 |
| Glutamate receptor ionotropic, NMDA 2A | 0 | 3 | 1 | 4 |
| Glutamate receptor ionotropic, NMDA 2B | 0 | 3 | 1 | 4 |
| Glutamate receptor ionotropic, NMDA 2C | 0 | 3 | 1 | 4 |
| Metabotropic glutamate receptor 1 | 0 | 0 | 1 | 1 |
| Metabotropic glutamate receptor 2 | 0 | 0 | 1 | 1 |
| Carbonic anhydrase-like protein, putative | 0 | 0 | 0 | 1 |
| Glutamate receptor ionotropic, NMDA 2D | 0 | 3 | 1 | 4 |
| Glutamate receptor ionotropic, NMDA 3B | 0 | 3 | 1 | 4 |
| Carbonic anhydrase 4 | 0 | 0 | 0 | 1 |
| Glutamate receptor ionotropic, NMDA 3A | 0 | 3 | 1 | 4 |
| Luciferase | 1 | 0 | 0 | 1 |
| thioredoxin reductase | 1 | 0 | 0 | 1 |
| RAR-related orphan receptor gamma | 3 | 0 | 0 | 3 |
| farnesoid X nuclear receptor | 3 | 0 | 0 | 3 |
| pregnane X nuclear receptor | 3 | 0 | 0 | 3 |
| estrogen nuclear receptor alpha | 3 | 0 | 0 | 3 |
| G | 2 | 0 | 0 | 2 |
| peroxisome proliferator-activated receptor delta | 2 | 0 | 0 | 2 |
| peroxisome proliferator activated receptor gamma | 2 | 0 | 0 | 2 |
| D(1A) dopamine receptor | 1 | 0 | 0 | 1 |
| chromobox protein homolog 1 | 1 | 0 | 0 | 1 |
| flap endonuclease 1 | 1 | 0 | 0 | 1 |
| survival motor neuron protein isoform d | 3 | 0 | 0 | 3 |
| Glutamate receptor ionotropic, NMDA 2D | 0 | 0 | 1 | 1 |
| Glutamate receptor ionotropic, NMDA 3B | 0 | 0 | 1 | 1 |
| Bile salt export pump | 0 | 1 | 0 | 1 |
| 5-hydroxytryptamine receptor 4 | 0 | 0 | 1 | 1 |
| Bile salt export pump | 0 | 2 | 0 | 2 |
| Interferon beta | 3 | 0 | 0 | 3 |
| HLA class I histocompatibility antigen, B alpha chain | 2 | 0 | 0 | 2 |
| Fatty acid-binding protein, liver | 0 | 1 | 0 | 1 |
| Muscarinic acetylcholine receptor M1 | 0 | 0 | 1 | 1 |
| Muscarinic acetylcholine receptor M3 | 0 | 0 | 1 | 1 |
| Muscarinic acetylcholine receptor M4 | 0 | 0 | 1 | 1 |
| Muscarinic acetylcholine receptor M5 | 0 | 0 | 1 | 1 |
| Muscarinic acetylcholine receptor M2 | 0 | 0 | 1 | 1 |
| Fatty acid-binding protein, intestinal | 0 | 1 | 0 | 1 |
| Peroxisome proliferator-activated receptor alpha | 0 | 0 | 1 | 1 |
| Peroxisome proliferator-activated receptor delta | 0 | 0 | 1 | 1 |
| Peroxisome proliferator-activated receptor gamma | 0 | 0 | 1 | 1 |
| Peroxisome proliferator-activated receptor gamma | 0 | 0 | 1 | 1 |
| Peroxisome proliferator-activated receptor delta | 0 | 0 | 1 | 1 |
| Glutamate receptor ionotropic, NMDA 1 | 0 | 0 | 1 | 1 |
| Peroxisome proliferator-activated receptor alpha | 0 | 0 | 1 | 1 |
| Glutamate receptor ionotropic, NMDA 2A | 0 | 0 | 1 | 1 |
| Glutamate receptor ionotropic, NMDA 2B | 0 | 0 | 1 | 1 |
| Glutamate receptor ionotropic, NMDA 2C | 0 | 0 | 1 | 1 |
| Glutamate receptor ionotropic, NMDA 3A | 0 | 0 | 1 | 1 |
| Inositol hexakisphosphate kinase 1 | 2 | 0 | 0 | 2 |
| cytochrome P450 2C9, partial | 2 | 0 | 0 | 2 |
| Chain A, Putative fructose-1,6-bisphosphate aldolase | 2 | 0 | 0 | 2 |
| Chain A, HADH2 protein | 1 | 0 | 0 | 1 |
| Chain B, HADH2 protein | 1 | 0 | 0 | 1 |
| Chain A, ATP-DEPENDENT DNA HELICASE Q1 | 1 | 0 | 0 | 1 |
| Chain A, Cruzipain | 1 | 0 | 0 | 1 |
| interleukin 8 | 1 | 0 | 0 | 1 |
| 15-lipoxygenase, partial | 1 | 0 | 0 | 1 |
| hypoxia-inducible factor 1 alpha subunit | 1 | 0 | 0 | 1 |
| USP1 protein, partial | 1 | 0 | 0 | 1 |
| TDP1 protein | 2 | 0 | 0 | 2 |
| GLI family zinc finger 3 | 2 | 0 | 0 | 2 |
| Microtubule-associated protein tau | 1 | 0 | 0 | 1 |
| AR protein | 3 | 0 | 0 | 3 |
| caspase 7, apoptosis-related cysteine protease | 1 | 0 | 0 | 1 |
| hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 1 | 0 | 0 | 1 |
| estrogen receptor 2 (ER beta) | 1 | 0 | 0 | 1 |
| nuclear receptor subfamily 1, group I, member 3 | 2 | 0 | 0 | 2 |
| progesterone receptor | 2 | 0 | 0 | 2 |
| cytochrome P450 family 3 subfamily A polypeptide 4 | 1 | 0 | 0 | 1 |
| glucocorticoid receptor [Homo sapiens] | 2 | 0 | 0 | 2 |
| retinoic acid nuclear receptor alpha variant 1 | 2 | 0 | 0 | 2 |
| retinoid X nuclear receptor alpha | 2 | 0 | 0 | 2 |
| estrogen-related nuclear receptor alpha | 2 | 0 | 0 | 2 |
| vitamin D (1,25- dihydroxyvitamin D3) receptor | 2 | 0 | 0 | 2 |
| caspase-3 | 1 | 0 | 0 | 1 |
| RAD51 | 0 | 1 | 0 | 1 |
| aryl hydrocarbon receptor | 2 | 0 | 0 | 2 |
| cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a | 2 | 0 | 0 | 2 |
| activating transcription factor 6 | 1 | 0 | 0 | 1 |
| v-jun sarcoma virus 17 oncogene homolog (avian) | 1 | 0 | 0 | 1 |
| Histone H2A.x | 2 | 0 | 0 | 2 |
| Caspase-7 | 1 | 0 | 0 | 1 |
| vitamin D3 receptor isoform VDRA | 1 | 0 | 0 | 1 |
| thyroid hormone receptor beta isoform a | 1 | 0 | 0 | 1 |
| caspase-3 | 1 | 0 | 0 | 1 |
| thyroid hormone receptor beta isoform 2 | 1 | 0 | 0 | 1 |
| huntingtin isoform 2 | 1 | 0 | 0 | 1 |
| histone-lysine N-methyltransferase 2A isoform 2 precursor | 1 | 0 | 0 | 1 |
| nuclear factor erythroid 2-related factor 2 isoform 1 | 2 | 0 | 0 | 2 |
| nuclear receptor ROR-gamma isoform 1 | 1 | 0 | 0 | 1 |
| peripheral myelin protein 22 | 1 | 0 | 0 | 1 |
| cytochrome P450 3A4 isoform 1 | 1 | 0 | 0 | 1 |
| caspase-1 isoform alpha precursor | 1 | 0 | 0 | 1 |
| Gamma-aminobutyric acid receptor subunit pi | 1 | 0 | 0 | 1 |
| Voltage-dependent calcium channel gamma-2 subunit | 2 | 0 | 0 | 2 |
| Cellular tumor antigen p53 | 2 | 0 | 0 | 2 |
| ATP-dependent translocase ABCB1 | 0 | 0 | 0 | 1 |
| Gamma-aminobutyric acid receptor subunit beta-1 | 1 | 0 | 0 | 1 |
| Gamma-aminobutyric acid receptor subunit delta | 1 | 0 | 0 | 1 |
| Gamma-aminobutyric acid receptor subunit gamma-2 | 1 | 0 | 0 | 1 |
| Glutamate receptor 2 | 2 | 0 | 0 | 2 |
| Gamma-aminobutyric acid receptor subunit alpha-5 | 1 | 0 | 0 | 1 |
| Gamma-aminobutyric acid receptor subunit alpha-3 | 1 | 0 | 0 | 1 |
| Gamma-aminobutyric acid receptor subunit gamma-1 | 1 | 0 | 0 | 1 |
| Gamma-aminobutyric acid receptor subunit alpha-2 | 1 | 0 | 0 | 1 |
| Gamma-aminobutyric acid receptor subunit alpha-4 | 1 | 0 | 0 | 1 |
| Gamma-aminobutyric acid receptor subunit gamma-3 | 1 | 0 | 0 | 1 |
| Gamma-aminobutyric acid receptor subunit alpha-6 | 1 | 0 | 0 | 1 |
| Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1 | 0 | 1 | 0 | 1 |
| Nuclear receptor ROR-gamma | 1 | 0 | 0 | 1 |
| Caspase-7 | 1 | 0 | 0 | 1 |
| Spike glycoprotein | 2 | 0 | 0 | 2 |
| Gamma-aminobutyric acid receptor subunit alpha-1 | 1 | 0 | 0 | 1 |
| Growth factor receptor-bound protein 2 | 0 | 1 | 0 | 1 |
| Gamma-aminobutyric acid receptor subunit beta-3 | 1 | 0 | 0 | 1 |
| Gamma-aminobutyric acid receptor subunit beta-2 | 1 | 0 | 0 | 1 |
| Pantothenate synthetase | 0 | 1 | 0 | 1 |
| Discoidin domain-containing receptor 2 | 0 | 1 | 0 | 1 |
| Growth factor receptor-bound protein 2 | 0 | 1 | 0 | 1 |
| Reverse transcriptase/RNaseH | 0 | 1 | 0 | 1 |
| GABA theta subunit | 1 | 0 | 0 | 1 |
| Peptide-N(4)-(N-acetyl-beta-glucosaminyl)asparagine amidase | 0 | 0 | 1 | 1 |
| ATPase family AAA domain-containing protein 5 | 2 | 0 | 0 | 2 |
| Ataxin-2 | 2 | 0 | 0 | 2 |
| Gamma-aminobutyric acid receptor subunit epsilon | 1 | 0 | 0 | 1 |
| Glycine receptor subunit alpha-1 | 0 | 0 | 1 | 1 |
| Sodium- and chloride-dependent GABA transporter 2 | 0 | 1 | 0 | 1 |
| Sodium- and chloride-dependent GABA transporter 3 | 0 | 1 | 0 | 1 |
| Sodium- and chloride-dependent glycine transporter 1 | 0 | 1 | 0 | 1 |
| Large neutral amino acids transporter small subunit 1 | 0 | 1 | 0 | 1 |
| Proton-coupled amino acid transporter 1 | 0 | 1 | 0 | 1 |
| Serine racemase | 0 | 1 | 0 | 1 |
| Olfactory receptor 51E2 | 0 | 0 | 1 | 1 |
| Sodium- and chloride-dependent glycine transporter 2 | 0 | 1 | 0 | 1 |
| Chain A, Beta-lactamase | 1 | 0 | 0 | 1 |
| Chain A, JmjC domain-containing histone demethylation protein 3A | 1 | 0 | 0 | 1 |
| Chain A, 2-oxoglutarate Oxygenase | 1 | 0 | 0 | 1 |
| Fumarate hydratase | 1 | 0 | 0 | 1 |
| thioredoxin glutathione reductase | 1 | 0 | 0 | 1 |
| apical membrane antigen 1, AMA1 | 1 | 0 | 0 | 1 |
| EWS/FLI fusion protein | 1 | 0 | 0 | 1 |
| cytochrome P450 2D6 | 1 | 0 | 0 | 1 |
| polyprotein | 1 | 0 | 0 | 1 |
| bromodomain adjacent to zinc finger domain 2B | 1 | 0 | 0 | 1 |
| IDH1 | 1 | 0 | 0 | 1 |
| thyroid stimulating hormone receptor | 1 | 0 | 0 | 1 |
| hemoglobin subunit beta | 1 | 0 | 0 | 1 |
| cellular tumor antigen p53 isoform a | 1 | 0 | 0 | 1 |
| 15-hydroxyprostaglandin dehydrogenase [NAD(+)] isoform 1 | 1 | 0 | 0 | 1 |
| transcriptional regulator ERG isoform 3 | 1 | 0 | 0 | 1 |
| urokinase-type plasminogen activator precursor | 1 | 0 | 0 | 1 |
| plasminogen precursor | 1 | 0 | 0 | 1 |
| urokinase plasminogen activator surface receptor precursor | 1 | 0 | 0 | 1 |
| histone acetyltransferase KAT2A isoform 1 | 1 | 0 | 0 | 1 |
| UDP-glucose 6-dehydrogenase | 0 | 1 | 0 | 1 |
| Solute carrier family 22 member 8 | 0 | 0 | 0 | 1 |
| Hypoxanthine-guanine phosphoribosyltransferase | 0 | 0 | 0 | 1 |
| Integrin beta-3 | 1 | 0 | 0 | 1 |
| Integrin alpha-IIb | 1 | 0 | 0 | 1 |
| UDP-glucose 6-dehydrogenase | 0 | 1 | 0 | 1 |
| Prostaglandin G/H synthase 1 | 0 | 1 | 0 | 1 |
| Purine nucleoside phosphorylase | 0 | 0 | 1 | 1 |
| UDP-glucuronosyltransferase 1A1 | 0 | 1 | 0 | 1 |
| [prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023] |