Compounds > ximoprofen
Page last updated: 2024-12-06

ximoprofen

Description Research Excerpts Clinical Trials Roles Classes Pathways Study Profile Bioassays Related Drugs Related Conditions Protein Interactions Research Growth

Description

ximoprofen : A monocarboxylic acid that is 2-phenylpropionic acid in which the phenyl group is substituted at the para position by a 3-(hydroxyimino)cyclohexyl group. [Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]

Cross-References

ID SourceID
PubMed CID5464206
SCHEMBL ID152468
MeSH IDM0171619

Synonyms (6)

Synonym
ximoprofen
56187-89-4
2-[4-[(3e)-3-hydroxyiminocyclohexyl]phenyl]propanoic acid
SCHEMBL152468
DTXSID40874686
13832jl; xifam

Research Excerpts

Bioavailability

ExcerptReferenceRelevance
" An oral dose was well absorbed in all three species as indicated by urinary excretion of 80%, 86% and 94% dose respectively in 5 days: excreted in the faeces were 14%, 2% and 2% dose respectively."( The metabolic fate of 14C-ximoprofen in rats, baboons and humans.
Chasseaud, LF; Hawkins, DR; Legeai, J; Mayo, BC; Taylor, IW, 1990)		0.28
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Research

Studies (7)

TimeframeStudies, This Drug (%)All Drugs %
pre-19902 (28.57)18.7374
1990's5 (71.43)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials2 (28.57%)5.53%
Reviews0 (0.00%)6.00%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Other5 (71.43%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]
ConditionIndicatedRelationship StrengthStudiesTrials
Ankylosing Spondylarthritis
[description not available]		04.3322
Spondylitis, Ankylosing
A chronic inflammatory condition affecting the axial joints, such as the SACROILIAC JOINT and other intervertebral or costovertebral joints. It occurs predominantly in young males and is characterized by pain and stiffness of joints (ANKYLOSIS) with inflammation at tendon insertions.		04.3322
Rheumatism
[description not available]		01.9710
Aging
The gradual irreversible changes in structure and function of an organism that occur as a result of the passage of time.		01.9710
Rheumatic Diseases
Disorders of connective tissue, especially the joints and related structures, characterized by inflammation, degeneration, or metabolic derangement.		01.9710
Liver Dysfunction
[description not available]		01.9710
Kidney Diseases
Pathological processes of the KIDNEY or its component tissues.		01.9710
Liver Diseases
Pathological processes of the LIVER.		01.9710