virantmycin

Description

Virantmycin is a naturally occurring antibiotic produced by the bacterium Streptomyces virantus. It exhibits potent antiviral activity against a broad spectrum of viruses, including influenza A and B, herpes simplex virus, and cytomegalovirus. The compound's mechanism of action involves inhibiting the synthesis of viral proteins, specifically by targeting the viral RNA polymerase. Virantmycin's unique structure, composed of a 2-amino-5-hydroxybenzoic acid moiety linked to a spirocyclic ring system, has attracted considerable interest in synthetic chemistry. Efforts to synthesize virantmycin have led to the development of novel synthetic methods and the exploration of structural modifications for improved antiviral activity. Its complex structure and promising antiviral activity make it an attractive target for drug development. Studies on virantmycin focus on understanding its mode of action, exploring its potential as a therapeutic agent against viral infections, and investigating its synthetic accessibility for potential drug optimization.'

virantmycin: has potent antifungal activity & potent inhibitory activity against DNA & RNA viruses; from Streptomyces nitrosporeus No. AM-2722; structure in 2nd source [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]