verbenachalcone: a dimeric dihydrochalcone with potentiating activity on nerve growth factor-action from Verbena littoralis; structure in first source [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]
| Flora | Rank | Flora Definition | Family | Family Definition |
|---|---|---|---|---|
| Verbena | genus | A plant genus of the family VERBENACEAE. Members contain verbenachalcone (dimeric dihydrochalcone), iridoids, and phenylethanoids.[MeSH] | Verbenaceae | A plant family of the order Lamiales, subclass Asteridae, class Magnoliopsida. The leaves are opposite or whorled. The flowers are aggregated in spikes, clusters, or racemes.[MeSH] |
| ID Source | ID |
|---|---|
| PubMed CID | 10098909 |
| CHEMBL ID | 519611 |
| MeSH ID | M0396728 |
| Synonym |
|---|
| verbenachalcone |
| CHEMBL519611 |
| 1-(2,4-dihydroxyphenyl)-3-[3-[4-[3-(2,4-dihydroxyphenyl)-3-oxopropyl]-2-methoxyphenoxy]-4-hydroxyphenyl]propan-1-one |
| Assay ID | Title | Year | Journal | Article |
|---|---|---|---|---|
| AID361178 | Induction of neurite outgrowth in rat PC12D cells at 1 to 30 uM in absence of nerve growth factor by microscopy | 2001 | Journal of natural products, Jun, Volume: 64, Issue:6 | Verbenachalcone, a novel dimeric dihydrochalcone with potentiating activity on nerve growth factor-action from Verbena littoralis. |
| AID361179 | Enhancement of nerve growth factor-stimulated neurite outgrowth in rat PC12D cells at > 10 uM by microscopy | 2001 | Journal of natural products, Jun, Volume: 64, Issue:6 | Verbenachalcone, a novel dimeric dihydrochalcone with potentiating activity on nerve growth factor-action from Verbena littoralis. |
| [information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023] | ||||
| Timeframe | Studies, This Drug (%) | All Drugs % |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 4 (80.00) | 29.6817 |
| 2010's | 1 (20.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| [information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] | ||
According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be weak demand-to-supply ratio for research on this compound.
| This Compound (12.50) All Compounds (24.57) |
| Publication Type | This drug (%) | All Drugs (%) |
|---|---|---|
| Trials | 0 (0.00%) | 5.53% |
| Reviews | 0 (0.00%) | 6.00% |
| Case Studies | 0 (0.00%) | 4.05% |
| Observational | 0 (0.00%) | 0.25% |
| Other | 5 (100.00%) | 84.16% |
| [information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] | ||