Page last updated: 2024-12-08

triphenylselenonium chloride

Description Research Excerpts Clinical Trials Roles Classes Pathways Study Profile Bioassays Related Drugs Related Conditions Protein Interactions Research Growth Market Indicators

Description

triphenylselenonium chloride: possesses significant chemopreventive activity against chemically-induced mammary carcinogenesis [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

Cross-References

ID SourceID
PubMed CID145836
SCHEMBL ID1158021
MeSH IDM0244944

Synonyms (11)

Synonym
selenonium, triphenyl-, chloride
selenonium, chloride
nsc36783
triphenylselenonium chloride
6158-73-2
nsc-36783
triphenylselanium chloride
nsc 36783
triphenylselenoniumchloride
SCHEMBL1158021
DTXSID60977168

Research Excerpts

Effects

ExcerptReferenceRelevance
"Triphenylselenonium chloride has excellent tumor inhibitory activity but does not support the repletion of selenoenzymes in animals that have been deprived of a bioavailable form of selenium."( Chemoprevention with triphenylselenonium chloride in selenium-deficient rats.
Ganther, HE; Ip, C; Lisk, DJ,
)
1.17

Bioavailability

ExcerptReferenceRelevance
"The present study compared the effects of four lipophilic forms of selenium with regard to cancer chemopreventive activity, tissue selenium accumulation, and bioavailability for synthesis of a selenoprotein."( Activities of structurally-related lipophilic selenium compounds as cancer chemopreventive agents.
Ganther, HE; Ip, C; Lisk, DJ,
)
0.13
" We also measured the activities of liver glutathione peroxidase and thioredoxin reductase as markers of selenium bioavailability in these different treatment conditions."( Chemoprevention with triphenylselenonium chloride in selenium-deficient rats.
Ganther, HE; Ip, C; Lisk, DJ,
)
0.45
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Research

Studies (11)

TimeframeStudies, This Drug (%)All Drugs %
pre-19900 (0.00)18.7374
1990's1 (9.09)18.2507
2000's2 (18.18)29.6817
2010's7 (63.64)24.3611
2020's1 (9.09)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Market Indicators

Research Demand Index: 12.18

According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be weak demand-to-supply ratio for research on this compound.

MetricThis Compound (vs All)
Research Demand Index12.18 (24.57)
Research Supply Index2.77 (2.92)
Research Growth Index4.96 (4.65)
Search Engine Demand Index0.00 (26.88)
Search Engine Supply Index0.00 (0.95)

This Compound (12.18)

All Compounds (24.57)

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials0 (0.00%)5.53%
Reviews0 (0.00%)6.00%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Other15 (100.00%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]