Trimethyl-(3-(trimethoxysilyl)propyl)ammonium is a quaternary ammonium salt with a trimethoxysilyl group attached to the propyl chain. It is commonly used as a coupling agent in the synthesis of hybrid organic-inorganic materials. The silyl group can react with hydroxyl groups on the surface of inorganic materials, such as silica or metal oxides, while the ammonium group can interact with organic molecules. This allows for the formation of robust and stable interfaces between organic and inorganic phases. The compound is often studied in the context of its application in various fields, including materials science, nanotechnology, and biomedicine. For instance, it has been investigated for its potential in the development of advanced coatings, adhesives, and drug delivery systems. The synthesis of trimethyl-(3-(trimethoxysilyl)propyl)ammonium typically involves the reaction of trimethylamine with (3-chloropropyl)trimethoxysilane. The compound is often used in solution form and its reactivity is influenced by factors such as pH, temperature, and the presence of catalysts.'
trimethyl-(3-(trimethoxysilyl)propyl)ammonium: used to modify glass fiber supports for gas-liquid phase sequencing of peptides [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]
| ID Source | ID |
|---|---|
| PubMed CID | 94462 |
| SCHEMBL ID | 120655 |
| MeSH ID | M0143498 |
| Synonym |
|---|
| (3-trimethoxysilylpropyl)trimethylammonium chloride |
| 35141-36-7 |
| n,n,n-trimethyl-3-(trimethoxysilyl)propan-1-aminium chloride |
| trimethyl-3-(trimethoxysilyl)propylammonium chloride |
| n-trimethoxysilylpropyl-n,n,n-trimethylammonium chloride 50% in methanol |
| S18450 |
| T2796 |
| trimethyl[3-(trimethoxysilyl)propyl]ammonium chloride |
| trimethyl-(3-(trimethoxysilyl)propyl)ammonium |
| 1-propanaminium, n,n,n-trimethyl-3-(trimethoxysilyl)-, chloride |
| 1-propanaminium, n,n,n-trimethyl-3-(trimethoxysilyl)-, chloride (1:1) |
| n-(3-trimethoxysilylpropyl)trimethylammonium chloride |
| einecs 252-393-5 |
| n-trimethoxysilylpropyl-n,n,n-trimethylammonium |
| AKOS015961045 |
| FT-0629607 |
| n-trimethoxysilylpropyl-n,n,n-trimethylammonium chloride |
| SCHEMBL120655 |
| n-(3-trimethoxysilylpropyl)-n,n,n-trimethylammonium chloride |
| n-trimethoxysilylpropyl-n,n,n-trimethylammonium chloride, 50% in methanol |
| DTXSID20872847 |
| mfcd00054225 |
| trimethyl[3-(trimethoxysilyl)propyl]azanium chloride |
| 3-(trimethoxysilyl)propyl-n,n,n-trimethylammonium-15n chloride, 98 atom % 15n, 97% (cp) |
| trimethyl[3-(trimethoxysilyl)propyl]ammonium chloride (ca. 50% in methanol) |
| trimethyl[3-(trimethoxysilyl)propyl]ammonium chloride, (ca. 50 percent in methanol) |
| trimethyl(3-trimethoxysilylpropyl)azanium;chloride |
| ntrimethoxysilylpropyln,n,ntrimethylammoniumchloride50% in methanol |
| n-[3-(trimethoxysilyl)propyl]-n,n,n-trimethylammonium chloride, 50% in methanol |
| n-(trimethoxysilylpropyl)trimethylammonium chloride, 50% in meth |
| n-trimethoxysilylpropyl-n,n,n-trimethylammoniumchloride,50%inmethanol |
| Timeframe | Studies, This Drug (%) | All Drugs % |
|---|---|---|
| pre-1990 | 1 (14.29) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 5 (71.43) | 29.6817 |
| 2010's | 1 (14.29) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| [information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] | ||
According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be weak demand-to-supply ratio for research on this compound.
| This Compound (11.96) All Compounds (24.57) |
| Publication Type | This drug (%) | All Drugs (%) |
|---|---|---|
| Trials | 0 (0.00%) | 5.53% |
| Reviews | 0 (0.00%) | 6.00% |
| Case Studies | 0 (0.00%) | 4.05% |
| Observational | 0 (0.00%) | 0.25% |
| Other | 7 (100.00%) | 84.16% |
| [information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] | ||