Compounds > trifluoromethanesulfonanilide
Page last updated: 2024-12-06

trifluoromethanesulfonanilide

Description Research Excerpts Clinical Trials Roles Classes Pathways Study Profile Bioassays Related Drugs Related Conditions Protein Interactions Research Growth Market Indicators

Cross-References

ID SourceID
PubMed CID68012
CHEMBL ID286402
SCHEMBL ID216185
MeSH IDM0102348

Synonyms (39)

Synonym
HMS1784H08
456-64-4
methanesulfonanilide, 1,1,1-trifluoro-
brn 2214142
n-phenyltriflamide
n-phenyl-1,1,1-trifluoromethanesulfonamide
trifluoromethanesulfonanilide
methanesulfonamide, n-phenyl-1,1,1-trifluoro-
CHEMBL286402
1,1,1-trifluoro-n-phenylmethanesulfonamide
AKOS003622726
4-12-00-01061 (beilstein handbook reference)
n-phenyltrifluoromethanesulfonamide
1,1,1-trifluoromethanesulfonanilide
phenyltriflamide
SCHEMBL216185
AM80898
methanesulfonamide, 1,1,1-trifluoro-n-phenyl-
T2985
n-phenyltrifluoromethane sulphonamide
n-phenyl trifluoromethanesulfonamide
n-phenyltrifluoromethane-sulfonamide
phnhtf
phenyl triflamide
c,c,c-trifluoro-n-phenylmethanesulfonamide
n-phenyltrifluoromethane sulfonamide
n-phenyltrifluoro-methanesulfonamide
n-phenyl(trifluoromethanesulfonamide)
FD13132
n-phenyl(trifluoromethane)sulfonamide
mfcd00521820
DTXSID20196570
DS-8107
BB 0304059
SB79856
CS-0156098
n-[(trifluoromethyl)sulfonyl]aniline
SY027422
EN300-117227
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Bioassays (4)

Assay IDTitleYearJournalArticle
AID588519A screen for compounds that inhibit viral RNA polymerase binding and polymerization activities2011Antiviral research, Sep, Volume: 91, Issue:3
High-throughput screening identification of poliovirus RNA-dependent RNA polymerase inhibitors.
AID540299A screen for compounds that inhibit the MenB enzyme of Mycobacterium tuberculosis2010Bioorganic & medicinal chemistry letters, Nov-01, Volume: 20, Issue:21
Synthesis and SAR studies of 1,4-benzoxazine MenB inhibitors: novel antibacterial agents against Mycobacterium tuberculosis.
AID23101Acidity of compound was determined1981Journal of medicinal chemistry, Nov, Volume: 24, Issue:11
Acidic epinephrine analogues derived from 1H, 3H-2,1,3-benzothiadiazole 2,2-dioxide and from trifluoromethanesulfonanilide. A new synthesis of 1H,3H-2,1,3-benzothiadiazole 2,2-dioxide.
AID23676Partition coefficient (logP)1981Journal of medicinal chemistry, Nov, Volume: 24, Issue:11
Acidic epinephrine analogues derived from 1H, 3H-2,1,3-benzothiadiazole 2,2-dioxide and from trifluoromethanesulfonanilide. A new synthesis of 1H,3H-2,1,3-benzothiadiazole 2,2-dioxide.
[information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023]

Research

Studies (5)

TimeframeStudies, This Drug (%)All Drugs %
pre-19901 (20.00)18.7374
1990's0 (0.00)18.2507
2000's1 (20.00)29.6817
2010's3 (60.00)24.3611
2020's0 (0.00)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Market Indicators

Research Demand Index: 12.30

According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be weak demand-to-supply ratio for research on this compound.

MetricThis Compound (vs All)
Research Demand Index12.30 (24.57)
Research Supply Index1.79 (2.92)
Research Growth Index4.09 (4.65)
Search Engine Demand Index0.00 (26.88)
Search Engine Supply Index0.00 (0.95)

This Compound (12.30)

All Compounds (24.57)

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials0 (0.00%)5.53%
Reviews0 (0.00%)6.00%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Other5 (100.00%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]
SubstanceRelationship StrengthStudiesTrialsClassesRoles
naphthalene
[no description available]		1.9610naphthalenes;
ortho-fused bicyclic arene		apoptosis inhibitor;
carcinogenic agent;
environmental contaminant;
mouse metabolite;
plant metabolite;
volatile oil component
phenol
[no description available]		1.9610phenolsantiseptic drug;
disinfectant;
human xenobiotic metabolite;
mouse metabolite
resorcinol
resorcinol: RN given refers to parent cpd; structure in Merck Index, 9th ed, #7951. resorcinol : A benzenediol that is benzene dihydroxylated at positions 1 and 3.		1.9610benzenediol;
phenolic donor;
resorcinols		erythropoietin inhibitor;
sensitiser
ConditionIndicatedRelationship StrengthStudiesTrials
Encephalitis, Polio
[description not available]		02.0610
Poliomyelitis
An acute infectious disease of humans, particularly children, caused by any of three serotypes of human poliovirus (POLIOVIRUS). Usually the infection is limited to the gastrointestinal tract and nasopharynx, and is often asymptomatic. The central nervous system, primarily the spinal cord, may be affected, leading to rapidly progressive paralysis, coarse FASCICULATION and hyporeflexia. Motor neurons are primarily affected. Encephalitis may also occur. The virus replicates in the nervous system, and may cause significant neuronal loss, most notably in the spinal cord. A rare related condition, nonpoliovirus poliomyelitis, may result from infections with nonpoliovirus enteroviruses. (From Adams et al., Principles of Neurology, 6th ed, pp764-5)		02.0610