Page last updated: 2024-11-12

tribromodiphenyl ether 28

Description Research Excerpts Clinical Trials Roles Classes Pathways Study Profile Bioassays Related Drugs Related Conditions Protein Interactions Research Growth Market Indicators

Description

4-bromophenyl 2,4-dibromophenyl ether : A polybromodiphenyl ether that is diphenyl ether in which the hydrogens at the 2, 4, and 4' positions have been replaced by bromines. [Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]

Cross-References

ID SourceID
PubMed CID12110098
CHEMBL ID217949
CHEBI ID138036
SCHEMBL ID7526745
MeSH IDM0527761

Synonyms (39)

Synonym
tribromodiphenyl ether 28
pbde-28
pbde 28
bde-28
2,4-dibromo-1-(4-bromophenoxy)benzene
2,4,4'-tribromodiphenyl ether
41318-75-6
bde28
4-bromophenyl 2,4-dibromophenyl ether
CHEBI:138036
2,4,4'-tribde
CHEMBL217949
2,4,4'-tribromodiphenylether
3xq4q434kf ,
unii-3xq4q434kf
benzene, 2,4-dibromo-1-(4-bromophenoxy)-
SCHEMBL7526745
DTXSID4052710
j151.979d ,
4-bromophenyl(2,4-dibromophenyl) ether
2,4,4'-tribromo(1,1'-oxybisbenzene)
1-(4-bromophenoxy)-2,4-dibromobenzene
2,4-dibromophenyl 4-bromophenyl ether
(4-bromophenoxy)-2,4-dibromobenzene
ether, p-bromophenyl 2,4-dibromophenyl
UPNBETHEXPIWQX-UHFFFAOYSA-N
pbde congener no. 28
bde no 28, analytical reference material
bde 28
2,4-dibromo-1-(4-bromophenoxy)benzene, 9ci
2,4,4-tribromodiphenyl ether
2,4-bibromophenyl 4-bromophenyl ether
Q27258186
methyl2-thiofuroate
pbde 28 50 microg/ml in nonane
pbde no. 28
EN300-11703280
2,4,4'-tribromodiphenyl ether solution
Z2049692236
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Drug Classes (1)

ClassDescription
polybromodiphenyl etherAn aromatic ether that is diphenyl ether carrying between 2 and 10 bromo substituents attached to the two benzene rings.
[compound class information is derived from Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]

Bioassays (2)

Assay IDTitleYearJournalArticle
AID274429Activity against human androgen receptor expressed in HepG2 cells assessed as renilla reporter gene activation in presence of 1 nM DHT at 1 uM after 40 hrs2006Journal of medicinal chemistry, Dec-14, Volume: 49, Issue:25
Identification of the brominated flame retardant 1,2-dibromo-4-(1,2-dibromoethyl)cyclohexane as an androgen agonist.
AID274424Displacement of androgen fluormone from androgen receptor at 100 uM2006Journal of medicinal chemistry, Dec-14, Volume: 49, Issue:25
Identification of the brominated flame retardant 1,2-dibromo-4-(1,2-dibromoethyl)cyclohexane as an androgen agonist.
[information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023]

Research

Studies (65)

TimeframeStudies, This Drug (%)All Drugs %
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (3.08)29.6817
2010's58 (89.23)24.3611
2020's5 (7.69)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Market Indicators

Research Demand Index: 12.06

According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be weak demand-to-supply ratio for research on this compound.

MetricThis Compound (vs All)
Research Demand Index12.06 (24.57)
Research Supply Index4.19 (2.92)
Research Growth Index6.25 (4.65)
Search Engine Demand Index0.00 (26.88)
Search Engine Supply Index0.00 (0.95)

This Compound (12.06)

All Compounds (24.57)

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials0 (0.00%)5.53%
Reviews0 (0.00%)6.00%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Other65 (100.00%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]