Compounds > triarachidonin
Page last updated: 2024-12-11

triarachidonin

Description Research Excerpts Clinical Trials Roles Classes Pathways Study Profile Bioassays Related Drugs Related Conditions Protein Interactions Research Growth

Cross-References

ID SourceID
PubMed CID9545801
CHEBI ID147308
SCHEMBL ID1502514
MeSH IDM0155749

Synonyms (23)

Synonym
23314-57-0
tg(20:4/20:4/20:4)
LMGL03011840
tg(20:4(5z,8z,11z,14z)/20:4(5z,8z,11z,14z)/20:4(5z,8z,11z,14z))
1,2,3-tri-(5z,8z,11z,14z-eicosatetraenoyl)-glycerol
triarachidonin
1,2,3-tri-(5z,8z,11z,14z-icosatetraenoyl)-glycerol
tag(20:4n6/20:4n6/20:4n6)
CHEBI:147308
tag(20:4(5z,8z,11z,14z),20:4(5z,8z,11z,14z),20:4(5z,8z,11z,14z))
SCHEMBL1502514
1,2,3-tri-[(cis,cis,cis,cis)-5,8,11,14-eicosatetraenoyl]-glycerol
tg(20:4w6/20:4w6/20:4w6)
tracylglycerol(20:4w6/20:4w6/20:4w6)
tag(20:4w6/20:4w6/20:4w6)
tg(20:4n6/20:4n6/20:4n6)
1-arachidonoyl-2-arachidonoyl-3-arachidonoyl-glycerol
tri-5(z),8(z),11z(),14(z)-eicosatetraenonin
tracylglycerol(20:4n6/20:4n6/20:4n6)
2,3-bis[[(5z,8z,11z,14z)-icosa-5,8,11,14-tetraenoyl]oxy]propyl (5z,8z,11z,14z)-icosa-5,8,11,14-tetraenoate
CS-0134307
PD044126
HY-131423

Research Excerpts

Toxicity

ExcerptReferenceRelevance
" Trilinolenin (18:3; omega-3) was toxic only after prolonged incubation."( Toxicity of polyunsaturated fatty acid esters for human monocyte-macrophages: the anomalous behaviour of cholesteryl linolenate.
Carpenter, KL; Hardwick, SJ; Hird, R; Law, NS; Marchant, CE; Mitchinson, MJ; Van Der Veen, C, 1997)		0.3
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Drug Classes (1)

ClassDescription
triacylglycerol 60:12A triglyceride in which the three acyl groups contain a total of 60 carbons and 12 double bonds.
[compound class information is derived from Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]

Pathways (1)

PathwayProteinsCompounds
De Novo Triacylglycerol Biosynthesis TG(20:4(5Z,8Z,11Z,14Z)/20:4(5Z,8Z,11Z,14Z)/20:4(5Z,8Z,11Z,14Z))513

Research

Studies (5)

TimeframeStudies, This Drug (%)All Drugs %
pre-19901 (20.00)18.7374
1990's4 (80.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials0 (0.00%)5.53%
Reviews0 (0.00%)6.00%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Other5 (100.00%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]
SubstanceRelationship StrengthStudiesTrialsClassesRoles
1-anilino-8-naphthalenesulfonate
1-anilino-8-naphthalenesulfonate: RN given refers to parent cpd. 8-anilinonaphthalene-1-sulfonic acid : A naphthalenesulfonic acid that is naphthalene-1-sulfonic acid substituted by a phenylamino group at position 8.		2.6730aminonaphthalene;
naphthalenesulfonic acid		fluorescent probe
5,8,11,14-eicosatetraynoic acid
5,8,11,14-Eicosatetraynoic Acid: A 20-carbon unsaturated fatty acid containing 4 alkyne bonds. It inhibits the enzymatic conversion of arachidonic acid to prostaglandins E(2) and F(2a).		3.0850long-chain fatty acid
egtazic acid
Egtazic Acid: A chelating agent relatively more specific for calcium and less toxic than EDETIC ACID.. ethylene glycol bis(2-aminoethyl)tetraacetic acid : A diether that is ethylene glycol in which the hydrogens of the hydroxy groups have been replaced by 2-[bis(carboxymethyl)amino]ethyl group respectively.		2.3820diether;
tertiary amino compound;
tetracarboxylic acid		chelator
bradykinin
[no description available]		1.9710oligopeptidehuman blood serum metabolite;
vasodilator agent
arachidonic acid
icosa-5,8,11,14-tetraenoic acid : Any icosatetraenoic acid with the double bonds at positions 5, 8, 11 and 14.. arachidonate : A long-chain fatty acid anion resulting from the removal of a proton from the carboxy group of arachidonic acid.		1.9710icosa-5,8,11,14-tetraenoic acid;
long-chain fatty acid;
omega-6 fatty acid		Daphnia galeata metabolite;
EC 3.1.1.1 (carboxylesterase) inhibitor;
human metabolite;
mouse metabolite
D-fructopyranose
[no description available]		1.9910cyclic hemiketal;
D-fructose;
fructopyranose		sweetening agent
dinoprostone
prostaglandin E2 : Prostaglandin F2alpha in which the hydroxy group at position 9 has been oxidised to the corresponding ketone. Prostaglandin E2 is the most common and most biologically potent of mammalian prostaglandins.		2.6730prostaglandins Ehuman metabolite;
mouse metabolite;
oxytocic
dinoprost
Dinoprost: A naturally occurring prostaglandin that has oxytocic, luteolytic, and abortifacient activities. Due to its vasocontractile properties, the compound has a variety of other biological actions.. prostaglandin F2alpha : A prostaglandins Falpha that is prosta-5,13-dien-1-oic acid substituted by hydroxy groups at positions 9, 11 and 15. It is a naturally occurring prostaglandin used to induce labor.		1.9710monocarboxylic acid;
prostaglandins Falpha		human metabolite;
mouse metabolite
alprostadil
[no description available]		1.9710prostaglandins Eanticoagulant;
human metabolite;
platelet aggregation inhibitor;
vasodilator agent
alpha-linolenic acid
linolenic acid : A two-membered subclass of octadecatrienoic acid comprising the (9Z,12Z,15Z)- and (6Z,9Z,12Z)-isomers. Linolenic acids are nutrients essential to the formation of prostaglandins and are also used in making paints and synthetic resins.. linolenate : A polyunsaturated fatty acid anion obtained by deprotonation of the carboxy group of either alpha- or gamma-linolenic acid.		2.3920linolenic acid;
omega-3 fatty acid		micronutrient;
mouse metabolite;
nutraceutical
trilinolein
trilinolein: RN given refers to (Z,Z)-isomer. 1,2,3-trilinoleoylglycerol : A triglyceride formed by acylation of the three hydroxy groups of glycerol with linoleic acid.		1.99101,2-diacyl-3-linoleoylglycerol;
1,3-diacyl-2-linoleoylglycerol;
linoleoyl containing 1,2,3-triacyl-sn-glycerol;
TG(18:2/18:2/18:2);
triglyceride		mouse metabolite
trilinolenin
trilinolenin: RN refers to (cis,cis,cis)-isomer. 1,2,3-trilinolenoylglycerol : A triglyceride formed by acylation of the three hydroxy groups of glycerol with linolenic acid.		2.3920triacylglycerol 54:9
triolein
Triolein: (Z)-9-Octadecenoic acid 1,2,3-propanetriyl ester.. triolein : A triglyceride formed by esterification of the three hydroxy groups of glycerol with oleic acid. Triolein is one of the two components of Lorenzo's oil.		1.9910triglycerideCaenorhabditis elegans metabolite;
plant metabolite
ConditionIndicatedRelationship StrengthStudiesTrials
Alloxan Diabetes
[description not available]		01.9910