Page last updated: 2024-12-06

thiocholesterol

Description Research Excerpts Clinical Trials Roles Classes Pathways Study Profile Bioassays Related Drugs Related Conditions Protein Interactions Research Growth Market Indicators

Thiocholesterol is a sulfur-containing analog of cholesterol. It is synthesized by reacting cholesterol with sulfur monochloride. Thiocholesterol has been shown to have various biological effects, including inhibition of cholesterol biosynthesis and reduction of LDL cholesterol levels. It also exhibits antioxidant properties and has been investigated for its potential therapeutic applications in conditions such as atherosclerosis. Thiocholesterol is studied because of its unique chemical structure and its ability to modulate lipid metabolism. The compound has been found to interfere with the synthesis and function of enzymes involved in cholesterol metabolism, leading to changes in cholesterol levels and potentially mitigating the risk of cardiovascular diseases.'

Cross-References

ID SourceID
PubMed CID65075
SCHEMBL ID26595
MeSH IDM0042842

Synonyms (17)

Synonym
thiocholesterol
cholest-5-ene-3-thiol, (3.beta.)-
1249-81-6
cholesteryl mercaptan
ai3-24121
einecs 215-003-4
nsc 137837
cholest-5-ene-3beta-thiol
SCHEMBL26595
cholest-5-ene-3-thiol #
cholest-5-ene-3b-thiol
5-cholestene-3beta-thiol
J-005186
(3s,9s,10r,13r,14s,17r)-10,13-dimethyl-17-((r)-6-methylheptan-2-yl)-2,3,4,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1h-cyclopenta[a]phenanthrene-3-thiol
DTXSID80883671
CS-0526314
HY-W414069

Research Excerpts

[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Research

Studies (13)

TimeframeStudies, This Drug (%)All Drugs %
pre-19901 (7.69)18.7374
1990's5 (38.46)18.2507
2000's4 (30.77)29.6817
2010's3 (23.08)24.3611
2020's0 (0.00)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Market Indicators

Research Demand Index: 19.96

According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be moderate demand-to-supply ratio for research on this compound.

MetricThis Compound (vs All)
Research Demand Index19.96 (24.57)
Research Supply Index2.64 (2.92)
Research Growth Index4.97 (4.65)
Search Engine Demand Index15.26 (26.88)
Search Engine Supply Index2.00 (0.95)

This Compound (19.96)

All Compounds (24.57)

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials0 (0.00%)5.53%
Reviews0 (0.00%)6.00%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Other13 (100.00%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]