Compounds > thiamphenicol glycinate acetylcysteinate
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thiamphenicol glycinate acetylcysteinate

Description

Cross-References

ID SourceID
PubMed CID3080935
MeSH IDM0092386

Synonyms (11)

Synonym
l-cysteine, n-acetyl-, ester with glycine 2-((dichloroacetyl)amino)-3-hydroxy-3-(4-(methylsulfonyl)phenyl)propyl ester, (r-(r*,r*))-
einecs 278-282-1
n-acetyl-l-cysteine, ester with (r-(r*,r*))-2-(dichloroacetamido)-3-hydroxy-3-(p-mesylphenyl)propyl glycinate
acetylcysteinate ester of thiamphenicol glycinate
thiamphenicol glycinate acetylcysteinate
fluimucil antibiotic (tn)
75639-30-4
D08582
[(2r,3r)-2-[(2,2-dichloroacetyl)amino]-3-hydroxy-3-(4-methylsulfonylphenyl)propyl] 2-amino-3-[[(2r)-1-methylsulfanyl-3-oxopropan-2-yl]amino]-3-oxopropanoate
DTXSID30997070
2,2-dichloro-n-{1-hydroxy-1-[4-(methanesulfonyl)phenyl]-3-[(3-{[1-(methylsulfanyl)-3-oxopropan-2-yl]imino}seryl)oxy]propan-2-yl}ethanimidic acid

Research

Studies (9)

TimeframeStudies, This Drug (%)All Drugs %
pre-19902 (22.22)18.7374
1990's2 (22.22)18.2507
2000's5 (55.56)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials4 (33.33%)5.53%
Reviews0 (0.00%)6.00%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Other8 (66.67%)84.16%
SubstanceStudiesClassesRolesFirst YearLast YearAverage AgeRelationship StrengthTrialspre-19901990's2000's2010'spost-2020
chloramphenicol
1
C-nitro compound;
carboxamide;
diol;
organochlorine compound		antibacterial drug;
antimicrobial agent;
Escherichia coli metabolite;
geroprotector;
Mycoplasma genitalium metabolite;
protein synthesis inhibitor		1999199925.0low001000
acetylcysteine
9
acetylcysteine;
L-cysteine derivative;
N-acetyl-L-amino acid		antidote to paracetamol poisoning;
antiinfective agent;
antioxidant;
antiviral drug;
ferroptosis inhibitor;
geroprotector;
human metabolite;
mucolytic;
radical scavenger;
vulnerary		1979200627.7high223400
erythromycin
2
cyclic ketone;
erythromycin		1999199925.0low002000
thiamphenicol
9
monocarboxylic acid amide;
sulfone		antimicrobial agent;
immunosuppressive agent		1979200627.7high223400
amoxicillin
2
penicillin allergen;
penicillin		antibacterial drug1999199925.0low002000
thiamphenicol glycinate
3
alpha-amino acid ester1979200230.0high110200
ConditionIndicatedStudiesFirst YearLast YearAverage AgeRelationship StrengthTrialspre-19901990's2000's2010'spost-2020
Acute Disease0
1
1980198044.0low010000
Bacterial Pneumonia0
1
1999199925.0low001000
Bronchitis0
1
2002200222.0low100100
Cough0
1
2002200222.0low100100
Group A Strep Infection0
1
1999199925.0low001000
Haemophilus Infections0
1
2000200024.0low001000
Infections, Respiratory0
3
1980200629.0medium111100
Pneumonia, Bacterial0
1
1999199925.0low001000
Respiratory Tract Diseases0
1
2001200123.0low000100
Respiratory Tract Infections0
3
1980200629.0medium111100
Streptococcal Infections0
1
1999199925.0low001000

Safety/Toxicity (1)

ArticleYear
Recent clinical evidence of the efficacy and safety of thiamphenicol glycinate acetylcysteinate and thiamphenicol glycinate.
Journal of chemotherapy (Florence, Italy), , Volume: 14, Issue:3		2002

Pharmacokinetics (1)

ArticleYear
Comparative effect of thiamphenicol glycinate, thiamphenicol glycinate N-acetylcysteinate, amoxicillin plus clavulanic acid, ceftriaxone and clarithromycin on pulmonary clearance of Haemophilus influenzae in an animal model.
Chemotherapy, , Volume: 46, Issue:4

Dosage (2)

ArticleYear
Aerosol antibiotic therapy in children with chronic upper airway infections: a potential alternative to surgery.
International journal of immunopathology and pharmacology, , Volume: 22, Issue:2
Recent clinical evidence of the efficacy and safety of thiamphenicol glycinate acetylcysteinate and thiamphenicol glycinate.
Journal of chemotherapy (Florence, Italy), , Volume: 14, Issue:3		2002