Page last updated: 2024-11-13

thailanstatin b

Description Research Excerpts Clinical Trials Roles Classes Pathways Study Profile Bioassays Related Drugs Related Conditions Protein Interactions Research Growth Market Indicators

Cross-References

ID SourceID
PubMed CID71665769
CHEMBL ID2333560
SCHEMBL ID15676287
MeSH IDM0585971

Synonyms (5)

Synonym
CHEMBL2333560
thailanstatin b ,
SCHEMBL15676287
EX-A5053
1426953-23-2
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Bioassays (14)

Assay IDTitleYearJournalArticle
AID1177561Cytotoxicity against human MDA-MB-468 cells after 4 days by MTS/cell proliferation assay2014Journal of natural products, Aug-22, Volume: 77, Issue:8
Cytotoxic Spliceostatins from Burkholderia sp. and Their Semisynthetic Analogues.
AID736711Antiproliferative activity against human SKOV3 cells assessed as growth inhibition measured after 48 hrs by MTT assay2013Journal of natural products, Apr-26, Volume: 76, Issue:4
Genomics-guided discovery of thailanstatins A, B, and C As pre-mRNA splicing inhibitors and antiproliferative agents from Burkholderia thailandensis MSMB43.
AID1177559Cytotoxicity against human BT474 cells after 4 days by MTS/cell proliferation assay2014Journal of natural products, Aug-22, Volume: 77, Issue:8
Cytotoxic Spliceostatins from Burkholderia sp. and Their Semisynthetic Analogues.
AID1177557Cytotoxicity against human NCI-H1975 cells after 4 days by MTS/cell proliferation assay2014Journal of natural products, Aug-22, Volume: 77, Issue:8
Cytotoxic Spliceostatins from Burkholderia sp. and Their Semisynthetic Analogues.
AID1895049Cytotoxicity against HEK293T cells assessed as inhibition in cell growth2021Journal of natural products, 05-28, Volume: 84, Issue:5
Spliceostatins and Derivatives: Chemical Syntheses and Biological Properties of Potent Splicing Inhibitors.
AID1895044Cytotoxicity against human MES-SA/Dx5 cells assessed as inhibition in cell growth2021Journal of natural products, 05-28, Volume: 84, Issue:5
Spliceostatins and Derivatives: Chemical Syntheses and Biological Properties of Potent Splicing Inhibitors.
AID736714Antiproliferative activity against human DU145 cells assessed as growth inhibition measured after 48 hrs by MTT assay2013Journal of natural products, Apr-26, Volume: 76, Issue:4
Genomics-guided discovery of thailanstatins A, B, and C As pre-mRNA splicing inhibitors and antiproliferative agents from Burkholderia thailandensis MSMB43.
AID1177558Cytotoxicity against human NCI-N87 cells after 4 days by MTS/cell proliferation assay2014Journal of natural products, Aug-22, Volume: 77, Issue:8
Cytotoxic Spliceostatins from Burkholderia sp. and Their Semisynthetic Analogues.
AID736717Stability of the compound in phosphate buffer at pH 7.4 at 37 degC by HPLC2013Journal of natural products, Apr-26, Volume: 76, Issue:4
Genomics-guided discovery of thailanstatins A, B, and C As pre-mRNA splicing inhibitors and antiproliferative agents from Burkholderia thailandensis MSMB43.
AID736713Antiproliferative activity against human NCI-H232A cells assessed as growth inhibition measured after 48 hrs by MTT assay2013Journal of natural products, Apr-26, Volume: 76, Issue:4
Genomics-guided discovery of thailanstatins A, B, and C As pre-mRNA splicing inhibitors and antiproliferative agents from Burkholderia thailandensis MSMB43.
AID1895048Cytotoxicity against human MES-SA cells assessed as inhibition in cell growth2021Journal of natural products, 05-28, Volume: 84, Issue:5
Spliceostatins and Derivatives: Chemical Syntheses and Biological Properties of Potent Splicing Inhibitors.
AID736715Inhibition of Pre-mRNA splicing in human HEK293 cells using p32-labeled CDC14-15 pre-mRNA by exonjunction complex (EJC) immunoprecipitation assay2013Journal of natural products, Apr-26, Volume: 76, Issue:4
Genomics-guided discovery of thailanstatins A, B, and C As pre-mRNA splicing inhibitors and antiproliferative agents from Burkholderia thailandensis MSMB43.
AID736712Antiproliferative activity against human MDA-MB-231 cells assessed as growth inhibition measured after 48 hrs by MTT assay2013Journal of natural products, Apr-26, Volume: 76, Issue:4
Genomics-guided discovery of thailanstatins A, B, and C As pre-mRNA splicing inhibitors and antiproliferative agents from Burkholderia thailandensis MSMB43.
AID1177560Cytotoxicity against human MDA-MB-DYT2 cells after 4 days by MTS/cell proliferation assay2014Journal of natural products, Aug-22, Volume: 77, Issue:8
Cytotoxic Spliceostatins from Burkholderia sp. and Their Semisynthetic Analogues.
[information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023]

Research

Studies (5)

TimeframeStudies, This Drug (%)All Drugs %
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's4 (80.00)24.3611
2020's1 (20.00)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Market Indicators

Research Demand Index: 12.80

According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be weak demand-to-supply ratio for research on this compound.

MetricThis Compound (vs All)
Research Demand Index12.80 (24.57)
Research Supply Index1.79 (2.92)
Research Growth Index4.59 (4.65)
Search Engine Demand Index0.00 (26.88)
Search Engine Supply Index0.00 (0.95)

This Compound (12.80)

All Compounds (24.57)

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials0 (0.00%)5.53%
Reviews1 (20.00%)6.00%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Other4 (80.00%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]