tetracenomycin X: from Nocardia mediterranea; structure given in first source [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]
| ID Source | ID |
|---|---|
| PubMed CID | 129395 |
| CHEMBL ID | 3609771 |
| MeSH ID | M0166646 |
| Synonym |
|---|
| 8-methoxy-elloramycinone |
| tetracenomycin x |
| C12380 , |
| 121245-07-6 |
| NSC376682 , |
| AC1L2VJ6 , |
| methyl (6ar,7s,10ar)-6a,7,12-trihydroxy-3,8,10a-trimethoxy-1-methyl-6,10,11-trioxo-7h-tetracene-2-carboxylate |
| 2-naphthacenecarboxylic acid, 6,6a,7,10,10a,11-hexahydro-6a,7,12-trihydroxy-3,8,10a-trimethoxy-1-methyl-6,10,11-trioxo-, methyl ester, (6ar-(6aalpha,7alpha,10aalpha))- |
| foeniculoside x |
| CHEMBL3609771 |
| DTXSID90923734 |
| methyl 6a,7,12-trihydroxy-3,8,10a-trimethoxy-1-methyl-6,10,11-trioxo-6,6a,7,10,10a,11-hexahydrotetracene-2-carboxylate |
| OCW , |
| methyl (6~{a}~{r},7~{s},10~{a}~{r})-3,8,10~{a}-trimethoxy-1-methyl-6~{a},7,12-tris(oxidanyl)-6,10,11-tris(oxidanylidene)-7~{h}-tetracene-2-carboxylate |
| Excerpt | Reference | Relevance |
|---|---|---|
| "Tetracenomycin X (Tcm X) has been reported to have antitumour activity in various cancers, but there have not been any studies on its activity with respect to lung cancer to date. " | ( Tetracenomycin X Exerts Antitumour Activity in Lung Cancer Cells through the Downregulation of Cyclin D1. Chen, S; Gan, M; Li, Y; Liu, B; Qiao, X; Shang, Y; Wang, C, 2019) | 3.4 |
| Assay ID | Title | Year | Journal | Article |
|---|---|---|---|---|
| AID1243573 | Cytotoxicity against human MCF7 cells assessed as growth inhibition after 48 hrs by sulforhodamine B assay | 2015 | Journal of natural products, Sep-25, Volume: 78, Issue:9 | Saccharothrixones A-D, Tetracenomycin-Type Polyketides from the Marine-Derived Actinomycete Saccharothrix sp. 10-10. |
| AID1243574 | Cytotoxicity against human K562 cells assessed as growth inhibition after 48 hrs by sulforhodamine B assay | 2015 | Journal of natural products, Sep-25, Volume: 78, Issue:9 | Saccharothrixones A-D, Tetracenomycin-Type Polyketides from the Marine-Derived Actinomycete Saccharothrix sp. 10-10. |
| AID1243572 | Cytotoxicity against human HepG2 cells assessed as growth inhibition after 48 hrs by sulforhodamine B assay | 2015 | Journal of natural products, Sep-25, Volume: 78, Issue:9 | Saccharothrixones A-D, Tetracenomycin-Type Polyketides from the Marine-Derived Actinomycete Saccharothrix sp. 10-10. |
| [information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023] | ||||
| Timeframe | Studies, This Drug (%) | All Drugs % |
|---|---|---|
| pre-1990 | 1 (11.11) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (11.11) | 29.6817 |
| 2010's | 3 (33.33) | 24.3611 |
| 2020's | 4 (44.44) | 2.80 |
| [information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] | ||
According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be weak demand-to-supply ratio for research on this compound.
| This Compound (12.82) All Compounds (24.57) |
| Publication Type | This drug (%) | All Drugs (%) |
|---|---|---|
| Trials | 0 (0.00%) | 5.53% |
| Reviews | 0 (0.00%) | 6.00% |
| Case Studies | 0 (0.00%) | 4.05% |
| Observational | 0 (0.00%) | 0.25% |
| Other | 9 (100.00%) | 84.16% |
| [information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] | ||